Search Results
Results 601 - 650 of 2097
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Reaume Kristen T - - 2008
OBJECTIVE: To review the literature assessing dual antiplatelet therapy with aspirin and clopidogrel and subsequently provide evidence-based recommendations for appropriate indications and length of therapy. DATA SOURCES: An English-language MEDLINE search (1950-December 2007) was conducted using the search terms antiplatelet, aspirin, thienopyridine, and clopidogrel to identify articles assessing dual antiplatelet ...
Koz Cem - - 2008
BACKGROUND: Transient ischemic attack (TIA) is presumed to be of cardiovascular origin. The aim of the study was to evaluate the electrocardiographic, echocardiographic, and clinical signs for predicting TIA recurrence. METHODS: A total of 100 consecutive patients presenting with a first episode of TIA without atrial fibrillation, previous stroke, and ...
Warnecke T - - 2008
BACKGROUND: Aspiration is a common complication in acute stroke patients and is strongly associated with a poor outcome. Due to an insufficient sensitivity and specificity of clinical bedside tests, further refinements are needed to improve the accuracy of clinical aspiration screening in acute stroke. OBJECTIVE: To assess the ability of ...
Lourenção Maria Inês Paes - - 2008
The objective of this study was to determine the effect that electromyographic biofeedback (EMG-BFB), used in conjunction with occupational therapy (OT) and functional electrical stimulation (FES), has on spasticity, range of motion, and upper extremity function in hemiplegic patients. A total of 59 patients treated at a university-based rehabilitation centre ...
Cokar Ozlem - - 2008
The aim of this study was to compare risk factors and concomitant potential cardioembolic sources detected by transthoracic (TTE) and transoesophageal echocardiography (TEE) in patients with lacunar and nonlacunar infarcts. Clinical data of 139 patients with a first episode of ischemic stroke who underwent both TTE and TEE were analysed. ...
Oliveira Carolina Camargo de - - 2008
The aim of this study was to characterize a group of patients (n=8) with sickle cell disease (SCD) and ischemic stroke concerning the clinical, neurological, imaging and progressive aspects. Data were collected from records and completed with an interview of patients and their parents. In this study there were 8 ...
Fulk George D - - 2008
BACKGROUND AND PURPOSE: Gait speed is commonly used to assess walking ability in persons with stroke. Previous research related to the psychometric properties of gait speed has been conducted primarily with individuals who were able to walk independently and/or were in the later stages of recovery after stroke. The purpose ...
Heilman Kenneth M - - 2008
BACKGROUND/OBJECTIVES: Patients with apraxic agraphia cannot correctly form the letters needed to write words but can correctly spell words orally. Apraxic agraphia (AA) is often associated with ideomotor apraxia and most commonly induced by stroke, but can be associated with degenerative diseases. In degenerative diseases, asymmetrical apraxic agraphia (AAA) has ...
Kobayashi Adam A II Klinika Neurologii, Instytut Psychiatrii i Neurologii, w Warszawie. - - 2008
High blood pressure is frequent in patients with acute stroke. It frequently returns back to normal values within the first days after onset. It is not yet established whether it requires treatment or not. The Efficacy of Nitric Oxide in Stroke (ENOS) trial aims to assess the efficacy of transdermal ...
Olawale, O A; ;
Background: Assessment of treatment efficacy through outcomes evaluation is an established practice in stroke rehabilitation. The evaluation of motor recovery is a cornerstone of the assessment of patients with stroke; and an integral component of stroke rehabilitation. Objective: The purpose of this study was to evaluate the recovery of motor ...
Burlina Alessandro P - - 2008
Fabry disease is an X-linked lysosomal deficiency of alpha-galactosidase A that results in cellular accumulation of galactoconjugates, mainly globotriaosylceramide, particularly in blood vessels. Neuroradiological findings include ischemic stroke, white matter lesions, vascular abnormalities (vertebrobasilar dolichoectasia and vessel tortuosity), and posterior thalamus involvement (the so called pulvinar sign). The purpose of ...
Palomeras E - - 2008
Delay in arrival to the emergency room (ER) may negatively influence outcome of stroke patients. We aim to analyze factors that influence extra-hospital delay in stroke patients. Two hundred and ninety-two consecutive stroke patients admitted in the ER were prospectively studied. Analysis was made to identify variables associated with <1- ...
Finsterer Josef - - 2008
Little is known about frequency, morphology, and causes of stroke in patients with left-ventricular hypertrabeculation/noncompaction (LVHT). Aim of this study was to find out how many LVHT-patients suffer from stroke, which abnormalities are found on cerebral imaging, and if stroke LVHT-patients differ from non-stroke LVHT-patients with regard to cardiac and ...
Tzvetanov P - - 2008
OBJECTIVE: To investigate whether elastin-derived peptides (EDP) are detectable in the cerebrospinal fluid (CSF) of healthy controls and of patients with acute brain ischemia and if so to assess possible trends in EDP levels in different groups of ischemic stroke patients (small-vessel disease vs. other ischemic strokes; first-ever vs. recurrent ...
Telman G - - 2008
BACKGROUND: There are data in the literature indicating that the number of microembolic signals (MES) in patients with patent foramen ovale (PFO) is directly related to stroke incidence and recurrence. We thus hypothesized that the amount of artificially induced microembolic signals monitored by contrast transcranial Doppler (cTCD) would be greater ...
Micheli Sara - - 2008
OBJECTIVE: Small-vessel disease is the most frequent cause of lacunar stroke. The aims of this study were to evaluate: 1) alternative causes of lacunar stroke other than small-vessel disease; 2) functional outcome of lacunar strokes due to small vessel disease compared to lacunar strokes due to alternative causes. METHODS: Consecutive ...
Porebska Agata - - 2008
OBJECTIVES: The purpose of the present study was to evaluate whether blood flow in the middle cerebral arteries (MCAs) in patients with atrial fibrillation (AF) during acute ischemic stroke is disturbed, as well as to assess if potential disturbances result from arrhythmia rather than a consequence of an embolus within ...
Nassief Abdullah - - 2008
BACKGROUND AND PURPOSE: Statins are widely used to reduce the risk of stroke in patients with coronary artery disease (CAD), but less so in patients without CAD. We reviewed recent trials for new evidence for the reduction in risk of stroke. SUMMARY OF REVIEW: In patients with CAD, moderate-intensity statin ...
Hjort Niels - - 2008
BACKGROUND AND PURPOSE: Blood-brain barrier disruption may be a predictor of hemorrhagic transformation (HT) in ischemic stroke. We hypothesize that parenchymal enhancement (PE) on postcontrast T1-weighted MRI predicts and localizes subsequent HT. METHODS: In a prospective study, 33 tPA-treated stroke patients were imaged by perfusion-weighted imaging, T1 and FLAIR before ...
Komori Takahiro - - 2008
Stroke is sometimes seen in patients with congestive heart failure (CHF). The factors that best predict incident stroke in hospitalized CHF patients are not well known. We performed this pilot study to explore the clinical markers of incident stroke in CHF patients. We studied 111 hospitalized patients with CHF (mean ...
Tsai Tung-Yao - - 2008
Painless aortic dissection with only focal neurological symptoms and signs can be a great challenge to the emergency physician. Inadvertently and erroneous treatment of stroke may threaten patient's life. We present a patient with painless aortic dissection (DeBakey I), which was initially misdiagnosed as brainstem stroke with catastrophic anticoagulant use. ...
Caty Gilles D - - 2008
OBJECTIVE: To develop a questionnaire (ABILOCO), based on the Rasch measurement model, that can assess locomotion ability in adult stroke patients (International Classification of Functioning, Disability and Health activity domain). DESIGN: Prospective study and questionnaire development. SETTING: A faculty hospital. PARTICIPANTS: Adult stroke patients (N=100) (age, 64+/-15y). The time since ...
von Büdingen Hans-Christian - - 2008
OBJECTIVE: To examine the influence of admission serum cholesterol levels (SCL) on severity of initial neurological deficit, neurological outcome at month 3 and neurological recovery in patients with acute first-ever ischemic stroke. METHODS: Prospectively collected data from 889 consecutive patients with first-ever acute ischemic stroke were retrospectively analysed. Patients who ...
Gupta Vishal - - 2008
BACKGROUND: Patent foramen ovale (PFO) is a well-recognized risk factor for ischemic strokes. The true prevalence of PFO among stroke patients is still under debate. Transesophageal echocardiography (TEE) is the "gold standard" in diagnosing PFO but the physiology requires right-to-left atrial shunting. In this report, we evaluate the prevalence of ...
Nahab Fadi - - 2008
There are limited data on the prevalence and prognosis of asymptomatic intracranial stenosis (AIS). Baseline cerebral angiograms and MR angiograms were used to determine AIS (50% to 99%) coexistent to symptomatic intracranial stenosis for patients enrolled in the Warfarin-Aspirin Symptomatic Intracranial Disease study. Coexisting AIS were detected in 18.9% (n=14/74) ...
Koren-Morag Nira - - 2008
BACKGROUND: Patients with coronary heart disease (CHD) are at increased risk of stroke. We investigated in a large cohort of patients with CHD the relationship between functional status, as assessed by the New York Heart Association (NYHA) classification, and incident ischemic stroke. METHODS: We followed up 15,524 patients with documented ...
Chiyonobu Tomohiro - - 2008
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is most commonly associated with a mitochondrial DNA A to G point mutation at nucleotide 3243 (A3243G) and individuals with the disorder present a wide range of multisystemic symptoms. Seizures in MELAS patients are often intractable and require multiple antiepileptic drugs. ...
Guercini F - - 2008
Strokes that remain without a definite cause even after extensive work-up are classified as cryptogenic. These constitute about 30-40% of all strokes. Stroke aetiology may remain undetermined for the following reasons: (i) the cause of stroke is transitory or reversible and the diagnostic work-out is not therefore performed at the ...
Strandberg Marjatta - - 2008
BACKGROUND AND PURPOSE: In this present study, we tried to find out if there is a subgroup of patients that should not undergo transoesophageal echocardiography (TEE) after an ischaemic stroke or transient ischaemic attack (TIA). METHODS: A total of 441 consecutive unselected patients with ischaemic stroke or TIA suitable for ...
Rallidis Loukianos S - - 2009
BACKGROUND: There is increasing evidence that cellular adhesion molecules (CAMs) play an important role in the pathophysiology of acute ischaemic stroke. We examined the prognostic value of soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) on in-hospital mortality in patients with ischaemic stroke. METHODS: We recruited ...
Lee S-H - - 2008
OBJECTIVES: Cerebral microbleeds (MBs) are known to be indicative of bleeding-prone microangiopathy and may predict incident intracerebral haemorrhage. However, there is controversy concerning the causal relationship between the presence of MBs and haemorrhagic transformation (HTf) after ischaemic stroke. METHODS: Of the 1034 patients with acute ischaemic stroke who were consecutively ...
Celik Turgay - - 2008
In the current study, DeltaQT dispersion (DeltaQTD) was found to be a new predictor of neurologic change which may be potentially useful in prediction of functional recovery in patients with acute cerebrovascular accident treated with thrombolytic treatment. We believe that DeltaQTD might be a new prognostic determiner in patients with ...
Rothwell P M - - 2008
Carotid bifurcation stenosis is an important cause of ischaemic stroke, particularly in patients with recent transient ischaemic attack or minor stroke. Large randomised trials of endarterectomy have shown that surgery reduces the risk of stroke in patients with > or =50% recently symptomatic carotid stenosis, but more recent research has ...
Nogueira Raul G - - 2008
INTRODUCTION: The use of coronary balloons in the cerebral vasculature is limited due to their poor trackability and increased risk of vessel injury. We report our experience using more compliant elastomer balloons for thrombus resistant to intraarterial (IA) pharmacological and mechanical thrombolysis in acute stroke. METHODS: We retrospectively analyzed 12 ...
Vergouwen Mervyn D I - - 2008
BACKGROUND AND PURPOSE: The recently published Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study showed that statins exert a marginally beneficial effect on stroke prevention in patients with a history of cerebrovascular disease. Interestingly, the magnitude of the beneficial effect shown in this study is smaller than in ...
Poli Daniela - - 2009
BACKGROUND: In atrial fibrillation (AF) patients stroke is nearly twice as likely to be fatal as non-AF patients and functional deficits are more likely to be severe among survivors. The incidence of stroke among AF patients is greatly reduced by oral anticoagulant treatment (OAT). However, fluctuation of anticoagulation levels is ...
Sarkar Suman
Cerebrovascular manifestations are uncommon presentations of scorpion sting in the Indian subcontinent. A prospective study was carried out on 42 patients with scorpion sting in the intensive care unit (ICU) of the Institute of Medical Sciences, Banaras Hindu University, Varanasi-05, INDIA, during the period of May 2005 to October 2007. ...
Chestnut Caitilin - - 2008
OBJECTIVE: To determine whether ipsilesional motor skills, which have been related to independent functioning, are present chronically after unilateral stroke and are more common in people with apraxia than in those without apraxia. DESIGN: Observational cohort comparing the performance of an able-bodied control group, stroke patients with left- or right-hemisphere ...
Liaw Lih-Jiun - - 2008
PURPOSE: To examine the relative reliability and absolute reliability of the Berg Balance Scale (BBS) and the Postural Assessment Scale for Stroke Patients (PASS) in chronic stroke patients. METHOD: A total of 52 mild to moderate stroke patients, who had a stroke more than 6 months previously, participated in the ...
Kalowska E - - 2008
BACKGROUND AND PURPOSE: Neurological deterioration following acute stroke is common and associated with increased morbidity and mortality. The underlying pathophysiological mechanisms are not fully understood, and it is difficult to predict which patients are at risk of deterioration. Our study aimed to assess if acute MRI findings could be used ...
Poppert Holger - - 2008
INTRODUCTION: A number of studies has addressed the possible association between patent foramen ovale (PFO) and stroke. However, the role of PFO in the pathogenesis of cerebral ischemia has remained controversial and most studies did not analyze patient subgroups stratified for gender, age and origin of stroke. METHODS: To address ...
Poppe Alexandre Y - - 2008
Ischaemic stroke is a devastating disease in the elderly with 30-50% 90-day mortality. Thrombolysis for stroke is potentially life saving and disability sparing in this group but the number of elderly patients studied in clinical trials, particularly those aged > or = 80 years, has been small. Indeed, < 50 ...
Dubow Jordan - - 2008
INTRODUCTION: This article describes two patients with major ischemic stroke symptoms who had extremely small areas of acute brain infarction, suggestive of acute intrahemispheric diaschisis. Both patients were using narcotic analgesics during their stroke, and in both cases the clinical deficits improved dramatically with naloxone. DISCUSSION: We postulate that the ...
Cojocaru Inimioara Mihaela - - 2008
Prothrombin (PT) is a target for antibodies with lupus anticoagulant (LA) activity. Anti-prothrombin antibodies (aPT) were recently identified as antibodies directed toward a phospholipid-binding protein. aPT are a new serologic marker of antiphospholipid syndrome. The objective was to detect aPT in a group of 46 patients with acute ischemic stroke ...
Inatomi Y - - 2008
OBJECTIVES: We investigated the incidence, clinical characteristics, outcome and factors associated with aphasia and early improvement in acute ischemic stroke. METHODS: We consecutively studied 855 patients with acute ischemic stroke who were admitted to our hospital within 48 h after onset and who were not comatose on admission. Assessment of ...
Paolucci Stefano - - 2008
BACKGROUND: This study was designed to quantify the probability of recovery of mobility in admission nonwalking stroke survivors. METHODS: We evaluated 437 of 500 consecutive patients admitted for sequelae of first ischemic stroke within the first month. We performed several logistic regressions using mobility status at discharge (independence in stair ...
Takeuchi Naoyuki - - 2008
We present a case report of a 56-yr-old chronic stroke patient with right hemiparesis who was treated with repetitive transcranial magnetic stimulation (rTMS) therapy. Before stroke, the patient had suffered an accident that led to paralysis and contracture of the left upper limb, and, subsequently, he was forced to use ...
Passero Stefano G - - 2008
OBJECTIVE: The long-term prognosis of patients with vertebrobasilar dolichoectasia (VBD) is unknown. The purpose of this study was to explore the natural history of VBD, evaluate its progression, and examine factors that may influence the clinical course of this condition. METHODS: We conducted a prospective clinical and imaging follow-up study ...
Ito Hirono - - 2008
We studied whether some variables differ between patients with right and left hemispheric ischemic stroke. A total of 383 cases were obtained from our department-based records between April 2003 and March 2006. Age distribution, sex, intracranial localization of anterior (carotid artery distribution) or posterior (vertebrobasilar artery distribution) circulation, mechanism subtypes ...
Gebruers N - - 2008
BACKGROUND: This study aimed to investigate the use of actigraphy (accelerometry) to measure disuse of the impaired arm in acute stroke patients. We correlated the National Institute of Health Stroke Scale (NIHSS) and the Fugl-Meyer Assessment arm section (FMA) findings with actigraphic data as a measure of validity. METHODS: Thirty-nine ...
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