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Results 551 - 600 of 2118
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Gladstone David J - - 2009
BACKGROUND AND PURPOSE: Warfarin is the most effective stroke prevention medication for high-risk individuals with atrial fibrillation, yet it is often underused. This study examined the magnitude of this problem in a large contemporary, prospective stroke registry. METHODS: We analyzed data from the Registry of the Canadian Stroke Network, a ...
Greer David M - - 2008
BACKGROUND AND PURPOSE: Many studies associate fever with poor outcome in patients with neurological injury, but this relationship is blurred by divergence in populations and outcome measures. We sought to incorporate all recent scholarship addressing fever in brain-injured patients into a comprehensive meta-analysis to evaluate disparate clinical findings. METHODS: We ...
Széplaki Gábor - - 2009
OBJECTIVE: According to data from animal models, complement activation plays a major role in the brain injury after acute ischemic stroke. Scarce findings are, however, available on the detection of complement activation products in stroke patients. METHODS: We have measured plasma levels of the five complement activation products (C1rC1sC1inh, C4d, ...
Haapaniemi E - - 2009
D-dimer (DD) is a fibrin degradation product present in negligible amounts in healthy individuals, but in thrombotic/fibrinolytic conditions substantially increases in plasma. Over the last two decades numerous studies have explored whether DD measurements would help stroke clinicians. An easy, reliable, and inexpensive test for stroke diagnosis, determination of stroke ...
Cowen R - - 2008
INTRODUCTION: The objective was to assess the management, and short- and longer-term outcome of patients presenting with an acute blue finger. PATIENTS AND METHODS: This was a retrospective, case-note review and prospective follow-up by telephone and general practitioner enquiry. All patients who presented with sudden onset blue discolouration of a ...
Martins Herlon Saraiva - - 2010
Although Aspergillus is widespread, clinically significant disease is rare in immunocompetent patients. We present a case of an otherwise healthy individual who developed cerebral vasculitis and stroke symptoms from Aspergillus, to raise awareness of this entity.
Pérennou D A DA Clinique de Médecine Physique et Réadaptation, Hôpital Nord-CHU Grenoble, Université Grenoble 1 degrees, Unité de Rééducation Neurologique du Grau du Roi, CHU Nîmes, France. - - 2008
The relationships between perception of verticality by different sensory modalities, lateropulsion and pushing behaviour and lesion location were investigated in 86 patients with a first stroke. Participants sat restrained in a drum-like framework facing along the axis of rotation. They gave estimates of their subjective postural vertical by signalling the ...
Alexandrov Andrei V - - 2008
Atherothrombosis is responsible for most acute ischemic manifestations of atherosclerotic disease, including stroke. Individuals with evidence of atherothrombotic disease in one vascular bed have a significant risk of recurrence and show increased vulnerability over time for other manifestations elsewhere in the vasculature. Ischemic event rates for asymptomatic patients with multiple ...
Hacke Werner - - 2008
Controversy exists over whether chronic antiplatelet therapy in patients with acute ischemic stroke is a contraindication to treatment with tissue plasminogen activator (tPA). Antiplatelets impair thrombocyte function and might, therefore, increase the risk of symptomatic intracerebral hemorrhage (SICH) after intravenous thrombolysis. This Practice Point commentary discusses a recent study by ...
Pruissen D M O - - 2008
BACKGROUND: Several genetic variants involved in hemostasis have been associated with ischemic stroke or myocardial infarction (MI). Stroke patients who carry a prothrombotic genotype may also be at increased risk for subsequent vascular events. PATIENTS AND METHODS: We included 887 patients with non-disabling cerebral ischemia of arterial origin, who were ...
Pilz Stefan - - 2008
BACKGROUND AND PURPOSE: Vitamin D deficiency is common among the elderly and may contribute to cerebrovascular diseases. We aimed to elucidate whether low vitamin D levels are predictive for fatal stroke. METHODS: The LUdwigshafen RIsk and Cardiovascular Health (LURIC) study includes 3316 patients who were referred to coronary angiography at ...
Hallevi Hen - - 2008
BACKGROUND: Most patients with cardioembolic stroke require long-term anticoagulation. Still, uncertainty exists regarding the best mode of starting long-term anticoagulation. Design, Setting, and Patients We conducted a retrospective review of all patients with cardioembolic stroke admitted to our center from April 1, 2004, to June 30, 2006, and not treated ...
Davenport, Sally
This paper presents the preliminary short and medium term outcomes from two chronic stroke subjects who used the SaeboFlex dynamic hand orthosis as part of their later stage rehabilitation.
Piper Cornelia - - 2008
BACKGROUND AND AIMS OF THE STUDY: In patients carrying mechanical valve prostheses it is assumed that cardioembolic strokes account for 70 - 90 % of clinically diagnosed thromboembolic complications. The etiology of stroke especially in older patients with mechanical heart valves may thus be multiple and not prosthetic valve-related in ...
Campos Tania Fernandes - - 2008
Various studies have been performed using the Social Rhythm Metric (SRM), though none has been developed with stroke patients. Stroke is a pathology that provokes a strong physical and social impact caused by an abnormality in cerebral circulation. Consequently, we performed two studies to validate the SRM and translate it ...
Haque M M - - 2008
The study was a cross sectional study conducted among 48 stroke patients in Medicine & Neuromedicine department of Mymensingh Medical College & Hospital. The objective of the study was to reveal the risk factors and other relevant information & immediate outcome of stroke patients. The sample size was 48 who ...
Mishina Masahiro - - 2008
Free radicals are known to activate coagulation and inhibit fibrinolysis. Edaravone, a free radical scavenger, protects vascular endothelial cells and neurons during acute brain ischemia in in vitro models. Hemorrhagic transformation and treatment outcomes were retrospectively examined in 76 patients with acute cardiogenic embolism treated with edaravone in addition to ...
Semplicini A - - 2008
BACKGROUND AND AIMS: Thrombolytic therapy with intravenous recombinant tissue plasminogen activator (rt-PA) improves outcome in patients with ischaemic stroke treated within 3 h of symptom onset, but its extended implementation is limited. A pilot study was designed to verify whether evaluation of patients with acute ischaemic stroke and their treatment ...
Prokopenko S V - - 2008
A specially developed proprioceptive correction costume was used for the restoration of motor functions in the proximal parts of the upper limb in central paralysis syndrome in patients in the late recovery and residual post-stroke states. The costume is a logical continuation of the Adeli and Gravistat proprioceptive correction systems, ...
Weimar C - - 2008
BACKGROUND: Risk stratification can contribute to individualised optimal secondary prevention in patients with cerebrovascular disease. OBJECTIVE: To prospectively investigate the prediction of the Essen Stroke Risk Score (ESRS) and a pathological Ankle Brachial Index (ABI) in consecutive patients hospitalised with acute ischaemic stroke or transient ischaemic attack (TIA) in 85 ...
Mehdi Nematbakhsh; Department of ...
BACKGROUND: The role of Nitric Oxide (NO) and its metabolites in stroke has been examined clinically and experimentally. The relationship between plasma NO level and Lesion Size (LS) or clinical severity of stroke is still under investigation. In this clinical study, the serum level of Nitrite (NI); the last metabolite ...
Peters Nils - - 2008
BACKGROUND: Mutations in the Notch3 gene are the cause of CADASIL, a hereditary small vessel disease leading to stroke and vascular dementia. The disease is characterized by ultrastructural granular deposits within small arterial vessels and degeneration of vascular smooth muscle cells. Yet, little is known about endothelial function in CADASIL. ...
Delgado-Mederos R - - 2008
OBJECTIVE: To evaluate the impact of early blood pressure (BP) changes on diffusion-weighted imaging (DWI) lesion evolution and clinical outcome in patients with stroke treated with IV tissue plasminogen activator (tPA). METHODS: We prospectively evaluated 80 patients with stroke with a documented middle cerebral artery occlusion treated with IV tPA. ...
Newman-Toker David E - - 2008
OBJECTIVE: To test the diagnostic accuracy of the horizontal head impulse test (h-HIT) of vestibulo-ocular reflex (VOR) function in distinguishing acute peripheral vestibulopathy (APV) from stroke. Most patients with acute vertigo, nausea/vomiting, and unsteady gait have benign APV (vestibular neuritis or labyrinthitis) as a cause. However, some harbor life-threatening brainstem ...
Montaner Joan - - 2008
BACKGROUND AND PURPOSE: Because there is no biologic marker offering precise information about stroke etiology, many patients receive a diagnosis of undetermined stroke even after all available diagnostic tests are done, precluding correct treatment. METHODS: To examine the diagnostic value of a panel of biochemical markers to differentiate stroke etiologies, ...
Kimura Kazumi - - 2008
BACKGROUND AND PURPOSE: MRI is useful for detecting early ischemic lesions before administration of tissue plasminogen activator in patients with hyperacute ischemic stroke. However, it is unclear whether early ischemic change seen on diffusion-weighted imaging (DWI) can be used to predict patient outcomes. METHODS: Consecutive patients with anterior circulation ischemic ...
Dani Krishna A - - 2008
BACKGROUND AND PURPOSE: European directives and legislation in some countries forbid inclusion of subjects incapable of consent in research if recruitment of patients capable of consent will yield similar results. We compared brain lesion volumes in stroke patients deemed to have capacity to consent with those defined as incapacitated. METHODS: ...
Force M - - 2008
OBJECTIVE: To evaluate the association of atrial septal abnormalities--patent foramen ovale (PFO), atrial septal aneurysm (ASA), or the combination of both (PFO+ASA)--with cryptogenic stroke or transient ischemic attack (TIA) in older patients. METHODS: We examined the prevalences of PFO, ASA, and PFO+ASA in 132 consecutive patients aged 55 years or ...
Biller José - - 2008
Patients with a history of ischemic stroke or transient ischemic attack (TIA) are at risk for recurrent ischemic events in the same or different vascular bed. Due to the central role of platelets in the spectrum of ischemic events in all vascular beds, antiplatelet therapy is a critical component of ...
Hokari Masaaki - - 2009
BACKGROUND: Reduced cerebral blood flow and cerebrovascular reactivity to acetazolamide (type 3 ischemia) is believed as an independent predictor for subsequent ischemic stroke in patients with occlusive carotid artery diseases. However, recent studies have shown that type 3 patients can be divided into 2 pathophysiologically different subgroups as follows: those ...
Park Hyung-Soon - - 2008
A portable teleassessment system was designed for remote evaluation of elbow impairments in patients with neurological disorders. A master device and a slave device were used to drive a mannequin arm and the patient's arm, respectively. The elbow flexion angle and torque were measured at both the master and slave ...
McCarron M O - - 2008
The frequency of adherence to the UK Driver and Vehicle Licensing Authority (DVLA) guidelines for patients referred to a neurovascular clinic is not known. Of 166 consecutive patients, 95 (57.2%) had a group 1 licence and 71 (42.7%) drove within a month of the event. Fifty of 85 (59%) transient ...
Masiero Stefano - - 2008
The aim of the study was to estimate the frequency of pneumonia and to determine the risk factors for this complication in poststroke patients with oropharyngeal dysphagia (OD). We prospectively followed up 67 patients (mean age 72.9+/-12.2 years) in the first 6 months after stroke, during which time we recorded ...
Terai Minako - - 2008
Increased arterial stiffness and impaired vasodilator response have been associated with cardiovascular events in high-risk patients. However, whether arterial changes predict the occurrence of hypertensive complications is still unclear. Therefore, we designed a hospital-based cohort study to examine the prognostic impact of arterial functional changes on stroke and cardiovascular diseases ...
Dharmasaroja Pornpatr - - 2008
BACKGROUND: Aspirin resistance has been defined as inability of aspirin to protect individuals from thrombotic complications or to produce an anticipated effect from laboratory tests of platelet function. Most reported information comes from Western patients with coronary artery disease and aspirin resistance is defined by laboratory criteria. The purpose of ...
Saeki Satoru - - 2008
The use of robotic-aided therapy in a patient with residual damage from a previous stroke was an attempt to improve function in a moderate to severe hemiparetic arm. Cortical activities associated with motor recovery are not well documented and require investigation. A chronic stroke patient with a severely affected arm ...
Huang Kuo-Lun - - 2008
OBJECTIVE: To determine the relationship between atherosclerosis and the short-term outcome following an acute ischemic stroke. METHODS: Quantitative measurements of ankle brachial index (ABI), color-coded carotid duplex (CCD), electrocardiography (ECG), and other cardiovascular risk factors were performed for acute ischemic stroke patients. Prevalent cardiovascular disease (PCVD) was defined when there ...
Song Hwa-Suk - - 2008
Elevation of serum cardiac troponin T (cTnT) is regarded as a specific marker of acute coronary syndrome. Serum cTnT can be increased in patients with acute ischemic stroke, but its clinical implications remain unclear. The aim of this study was to identify the relationships between elevated cTnT and stroke severity, ...
Schepers Vera P M VP Center of Excellence for Rehabilitation Medicine Utrecht, Rehabilitation Center De Hoogstraat, Rembrandtkade 10, Utrecht, The Netherlands. - - 2008
To determine whether there is a difference between patients with a cerebral infarction and those with an intracerebral haemorrhage with respect to the development of independence in activities of daily living over the first year post-stroke. Patients after first-ever stroke who were admitted to an inpatient rehabilitation programme were included. ...
Lee Sang-Hak - - 2008
BACKGROUND: Although several risk factors for stroke have been reported in patients with atrial fibrillation (AF), the relation of LV diastolic dysfunction to stroke is still uncertain in these patients. We evaluated the relationship between tissue Doppler-derived index, E/E', as well as other clinical and echocardiographic parameters and ischemic stroke ...
Hjalmarsen Audhild A Department of Medicine, Pulmonary Division, University Hospital of North Norway, N 9038 Tromsø, Norway. - - 2008
oxygen levels are decreased in older people especially in the supine position, and during sleep. Geriatric inpatients often suffer from stroke and heart disease. Respiratory control may be substantially affected. the aim of this study was to examine oxygen levels during night in inpatients on geriatric medical wards to find ...
Allport Louise E - - 2008
We report our management of a patient presenting with concomitant cortical stroke and pulmonary embolism. Stroke symptoms and respiratory distress were present for 2 h at the time of initial assessment. The patient was treated with intravenous tissue plasminogen activator (tPA). Intravenous unfractionated heparin was given 24 h after treatment ...
Nardi Katiuscia - - 2008
BACKGROUND: Several studies were carried out to investigate the occurrence of headache attributed to acute stroke in patients with a lifetime history of migraine. METHODS: In a case-control series of 96 acute stroke patients with a lifetime history of migraine (M+) and 96 stroke patients without (M-), ischemic stroke patients ...
Mori Nobuyuki - - 2008
Moyamoya disease (MMD) is a rare disorder of unknown etiology in which terminal portions of the internal carotid arteries become steno-occlusive, with fine collateral "moyamoya vessels" formed secondarily, resulting in serial ischemic strokes throughout its clinical course. Whole-brain histogram (WBH) of diffusion tensor imaging (WBH-DTI) is an analytical tool whose ...
Bazan Hernan A - - 2008
Recent reports from single institutions have confirmed the efficacy of carotid endarterectomy (CEA) performed in the urgent or emergent setting, although with higher perioperative mortality and morbidity. We determined the results of urgently performed CEA in academic and community hospitals and whether patient or hospital factors affected outcome. The records ...
Mok Vincent C - - 2008
OBJECTIVE: (1) To determine and compare the rates of cognitive change using global and executive psychometric measures between lacunar stroke patients and matched controls and; (2) to identify features associated with cognitive changes in patients. METHODS: Sixty-one lacunar stroke patients and 35 demographically-matched controls were followed-up for 28.6 months (range ...
Vukovic Mile - - 2008
In this study we investigated the recovery patterns of language and cognitive functions in patients with post-traumatic language processing deficits and in patients with aphasia following a stroke. The correlation of specific language functions and cognitive functions was analyzed in the acute phase and 6 months later. Significant recovery of ...
Xue Jing - - 2008
The ability to rapidly and accurately evaluate the location and extent of hyperacute brain ischemia is of major clinical importance. Herein, we aimed to develop imaging criteria to classify the ischemic lesion by computed tomography (CT) perfusion (CTP) and CT angiography (CTA) in hyperacute ischemic stroke patient. Non-contrast-enhanced CT, CTP ...
Rojas Juan Ignacio - - 2008
BACKGROUND: Transesophageal echocardiography (TEE) constitutes a valuable tool in patients with stroke and cardiac embolization, but its indication is controversial in lacunar stroke. The purpose of this study was to assess the findings of TEE in lacunar stroke. METHODS: Initial symptoms, brain computed tomography or magnetic resonance imaging, and TEE ...
Smajlović Dzevdet - - 2008
Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke despite progression in medical science. The aim of the study was to analyze the frequency, risk factors, localization and 30-day prognosis in patients with intracerebral hemorrhage. We analyzed 352 patients with intracerebral hemorrhage (ICH) hospitalized at the ...
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