Search Results
Results 501 - 550 of 2093
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Robbers-Visser Daniëlle - - 2008
PURPOSE: To assess pulmonary artery (PA) size, flow variables, and wall shear stress (WSS) in patients after Fontan operation at a young age. MATERIALS AND METHODS: Flow in the branch PA was obtained with phase contrast velocity-encoded cardiovascular magnetic resonance imaging in 14 patients before and after low-dose dobutamine stress ...
Lindley Richard I - - 2008
BACKGROUND: The heterogeneity of the pathology of stroke has been a major difficulty in assessing new treatments for acute stroke, and contributes to the complexity of stroke medicine. Some underlying mechanisms are poorly understood, such as small vessel (lacunar) disease. New technology such as advanced brain imaging has transformed our ...
Richet Hervé - - 2008
The aim of this study was to assess whether non-specific clinical signs or biological results can identify patients with a high probability of infective endocarditis (IE) to improve outcome. All patients tested for IE were included in a cohort and classified according to the modified Duke criteria. Patients with rejected ...
Dursun N - - 2009
AIM: The purpose of this study was to show if constraint induced movement therapy (CIMT) is effective in a Turkish stroke patient population and whether the effectiveness could be measured by a different evaluation tool, i.e. Kocaeli Functional Evaluation Test (KFET). METHODS: Twenty-five patients with subacute or chronic stroke were ...
Dursun N - - 2008
AIM: The purpose of this study was to show if constraint induced movement therapy (CIMT) is effective in a Turkish stroke patient population and whether the effectiveness could be measured by a different evaluation tool, i.e. Kocaeli Functional Evaluation Test (KFET). METHODS: Twenty-five patients with subacute or chronic stroke were ...
Staszewski J - - 2009
OBJECTIVE: Our aim was to compare the course of IS due to ptAF and pxAF. METHODS: A prospective, single-center study was conducted in patients with AF and acute IS with 6-month follow-up. RESULTS: We included 178 patients: 70 (39%) with pxAF and 108 (61%) with ptAF. Compared with patients with ...
De Silva Deidre Anne - - 2009
Inflammation, a vascular risk factor, is more pronounced among ethnic South Asians compared to ethnic Chinese in the general population. We compared serum erythrocyte sedimentation rate (ESR) levels between ethnic South Asian and Chinese acute ischemic stroke patients, and further investigated if metabolic syndrome or central obesity could account for ...
Kwon Do-Young - - 2008
The significant association between heart rate variability (HRV) and the outcomes of stroke has led to a particular interest in alterations of HRV in stroke patients. To date, several clinical variables have been associated with alterations of HRV in stroke patients. The present study adds the new information that carotid ...
Bicakci Sebnem - - 2008
To evaluate the effects of corrected QT dispersion (QTcd) on patients` prognosis with early stage non-lacunar ischemic stroke, regardless of location of the lesion. In this non-randomized prospective study, stroke patients were evaluated in the intensive care unit of Cukurova University Hospital, School of Medicine, Adana, Turkey, from 2002-2003. Neurologic ...
Zubkov Alexander Y - - 2008
OBJECTIVE: Computed tomographic angiography (CTA) was invented more than 20 years ago, but only gained acceptance recently, thanks to advancements in the computer technology. It can demonstrate areas of arterial stenosis or occlusion with accuracy nearly that of digital subtraction angiography (DSA). It is also able to clearly illustrate calcification, ...
Beridze M - - 2008
To address the issues of immunological tolerance to ischemia injury in the brain we have researched ischemic stroke patients with and without prodromal transitional ischemic attacks (TIAs) for several blood acute phase reactants involved in inflammatory reactions in respect to initial infarct size, clinical course of disease and functional outcome ...
Hummel Friedhelm C - - 2008
Stroke is the leading cause of disability in the adult population of western industrialized countries. Despite significant improvements of acute stroke care, two thirds of stroke survivors have to cope with persisting neurologic deficits. Adjuvant brain stimulation is a novel approach to improving the treatment of residual deficits after stroke. ...
Sarkar Purnima Dey - - 2008
Stroke is the leading cause of mortality and long term disability among adults in industrialized countries. Oxidative stress is an independent risk actor by inducing production of oxygen free radicals in ischemic stroke. Because a relationship may be associated between ox-ldl and paraoxanase, the aim of this study was to ...
Khella Sami L - - 2008
Patients with chronic kidney disease (CKD) are predisposed to stroke, especially as the estimated glomerular filtration rate decreases. This update reviews the pathologic mechanisms particular to this stroke population. The treatment for primary and secondary prevention of stroke is reviewed with respect to antiplatelet agents, anticoagulants, surgery, and carotid stenting. ...
Steiner Sabine - - 2009
INTRODUCTION: Carotid stenting (CS) has become a therapeutic alternative to endarterectomy in selected patients. Periinterventional plaque thromboembolism leading to neurological ischemic events remain the major risk of the procedure. We prospectively studied the potential role of thrombophilic conditions including anticardiolipin antibodies (ACA, IgG and IgM isotype), lupus anticoagulants, activated protein ...
Udby Blicher Jakob - - 2009
INTRODUCTION: The contribution of hyperreflexia to impairment after stroke is debated. Spinal motoneuron excitability in healthy subjects and stroke patients with and without spasticity was compared. METHODS: Twenty-four patients with single stroke more than 6 months ago and 18 gender-matched healthy volunteers were included. Spasticity was assessed according to the ...
Hsieh Yu-Wei - - 2008
BACKGROUND: The minimal clinically important difference (MCID) of the Stroke Rehabilitation Assessment of Movement (STREAM) measure is unknown, which limits the application and interpretation of change scores. OBJECTIVE: To estimate the MCID of the 3 subscales (ie, lower extremity, upper extremity, and mobility subscales) of the STREAM using the method ...
Terruzzi Alessandro - - 2008
OBJECTIVE: We have sought to relate C-reactive protein (CRP), a peripheral marker of inflammation frequently elevated in stroke patients, with aetiology and prognosis of acute cerebral infarction. PATIENTS AND METHODS: Patients were included after a first-ever CT/MR documented cerebral infarction. CRP was measured from blood samples taken within the 6th ...
Simmons Lucy - - 2008
BACKGROUND: Motor imagery may enhance motor recovery after stroke. OBJECTIVES: To estimate the proportion of patients able to perform motor imagery, the feasibility of delivery of motor imagery training (MIT), and the effects of MIT on motor recovery in an exploratory study. METHODS: An immediate pretreatment and posttreatment single-group design ...
Bondanelli M - - 2008
Stroke is one of the main causes of death and disability in the adult population. Changes in pituitary hormone secretion may be observed during the acute phase of stroke, representing part of the adaptive response to injury. However, reduced pituitary hormone secretion, caused by pituitary and/or hypothalamus damage, may also ...
Heil Jason W - - 2008
Intravenous tissue plasminogen activator (t-PA) is currently approved by the US Food and Drug Administration (FDA) for the treatment of ischemic stroke in patients > 18 years of age who present within 3 hours of stroke onset and meet certain criteria. We report a case of a 16-year-old, previously healthy ...
Shakarishvili R - - 2008
Investigations aimed at studying of peripheral blood levels of free nitric oxide (NO) and proinflammatory cytokines IL-1beta, IL- 6 and TNF-alpha in correlation with initial ischemic lesion size and neurological dynamics during a month of acute brain ischemia. Forty two patients aged 60-75 (26 male) have been investigated. Initial neurological ...
Tan Teng-Yeow - - 2008
PURPOSE: Microembolic signals (MES) can be detected in a variety of clinical situations using conventional transcranial Doppler (TCD) sonography. We studied the prevalence of positive MESs in acute stroke patients with intracranial artery stenosis using power M-mode Doppler (PMD) sonography and also tested the feasibility of this new technique. METHOD: ...
Kostálová Milena - - 2008
PRIMARY OBJECTIVE: To assess the criterion and construct validity and inter-rater reliability of the Czech version of the Mississippi Aphasia Screening Test (MASTcz). RESEARCH DESIGN: Prospective evaluation of consecutive inpatients admitted to the stroke unit of a university hospital within 60 days of onset of a unilateral left hemispheric ischaemic ...
Lee Gha-Hyun - - 2008
Microbleeds (MBs), proposed as a biomarker for microangiopathy, have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear. We describe two patients who developed warfarin-induced ICH at the site of MBs documented ...
Gladstone David J - - 2009
BACKGROUND AND PURPOSE: Warfarin is the most effective stroke prevention medication for high-risk individuals with atrial fibrillation, yet it is often underused. This study examined the magnitude of this problem in a large contemporary, prospective stroke registry. METHODS: We analyzed data from the Registry of the Canadian Stroke Network, a ...
Greer David M - - 2008
BACKGROUND AND PURPOSE: Many studies associate fever with poor outcome in patients with neurological injury, but this relationship is blurred by divergence in populations and outcome measures. We sought to incorporate all recent scholarship addressing fever in brain-injured patients into a comprehensive meta-analysis to evaluate disparate clinical findings. METHODS: We ...
Széplaki Gábor - - 2009
OBJECTIVE: According to data from animal models, complement activation plays a major role in the brain injury after acute ischemic stroke. Scarce findings are, however, available on the detection of complement activation products in stroke patients. METHODS: We have measured plasma levels of the five complement activation products (C1rC1sC1inh, C4d, ...
Haapaniemi E - - 2009
D-dimer (DD) is a fibrin degradation product present in negligible amounts in healthy individuals, but in thrombotic/fibrinolytic conditions substantially increases in plasma. Over the last two decades numerous studies have explored whether DD measurements would help stroke clinicians. An easy, reliable, and inexpensive test for stroke diagnosis, determination of stroke ...
Cowen R - - 2008
INTRODUCTION: The objective was to assess the management, and short- and longer-term outcome of patients presenting with an acute blue finger. PATIENTS AND METHODS: This was a retrospective, case-note review and prospective follow-up by telephone and general practitioner enquiry. All patients who presented with sudden onset blue discolouration of a ...
Martins Herlon Saraiva - - 2010
Although Aspergillus is widespread, clinically significant disease is rare in immunocompetent patients. We present a case of an otherwise healthy individual who developed cerebral vasculitis and stroke symptoms from Aspergillus, to raise awareness of this entity.
Pérennou D A DA Clinique de Médecine Physique et Réadaptation, Hôpital Nord-CHU Grenoble, Université Grenoble 1 degrees, Unité de Rééducation Neurologique du Grau du Roi, CHU Nîmes, France. - - 2008
The relationships between perception of verticality by different sensory modalities, lateropulsion and pushing behaviour and lesion location were investigated in 86 patients with a first stroke. Participants sat restrained in a drum-like framework facing along the axis of rotation. They gave estimates of their subjective postural vertical by signalling the ...
Alexandrov Andrei V - - 2008
Atherothrombosis is responsible for most acute ischemic manifestations of atherosclerotic disease, including stroke. Individuals with evidence of atherothrombotic disease in one vascular bed have a significant risk of recurrence and show increased vulnerability over time for other manifestations elsewhere in the vasculature. Ischemic event rates for asymptomatic patients with multiple ...
Hacke Werner - - 2008
Controversy exists over whether chronic antiplatelet therapy in patients with acute ischemic stroke is a contraindication to treatment with tissue plasminogen activator (tPA). Antiplatelets impair thrombocyte function and might, therefore, increase the risk of symptomatic intracerebral hemorrhage (SICH) after intravenous thrombolysis. This Practice Point commentary discusses a recent study by ...
Pruissen D M O - - 2008
BACKGROUND: Several genetic variants involved in hemostasis have been associated with ischemic stroke or myocardial infarction (MI). Stroke patients who carry a prothrombotic genotype may also be at increased risk for subsequent vascular events. PATIENTS AND METHODS: We included 887 patients with non-disabling cerebral ischemia of arterial origin, who were ...
Pilz Stefan - - 2008
BACKGROUND AND PURPOSE: Vitamin D deficiency is common among the elderly and may contribute to cerebrovascular diseases. We aimed to elucidate whether low vitamin D levels are predictive for fatal stroke. METHODS: The LUdwigshafen RIsk and Cardiovascular Health (LURIC) study includes 3316 patients who were referred to coronary angiography at ...
Hallevi Hen - - 2008
BACKGROUND: Most patients with cardioembolic stroke require long-term anticoagulation. Still, uncertainty exists regarding the best mode of starting long-term anticoagulation. Design, Setting, and Patients We conducted a retrospective review of all patients with cardioembolic stroke admitted to our center from April 1, 2004, to June 30, 2006, and not treated ...
Davenport, Sally
This paper presents the preliminary short and medium term outcomes from two chronic stroke subjects who used the SaeboFlex dynamic hand orthosis as part of their later stage rehabilitation.
Piper Cornelia - - 2008
BACKGROUND AND AIMS OF THE STUDY: In patients carrying mechanical valve prostheses it is assumed that cardioembolic strokes account for 70 - 90 % of clinically diagnosed thromboembolic complications. The etiology of stroke especially in older patients with mechanical heart valves may thus be multiple and not prosthetic valve-related in ...
Campos Tania Fernandes - - 2008
Various studies have been performed using the Social Rhythm Metric (SRM), though none has been developed with stroke patients. Stroke is a pathology that provokes a strong physical and social impact caused by an abnormality in cerebral circulation. Consequently, we performed two studies to validate the SRM and translate it ...
Haque M M - - 2008
The study was a cross sectional study conducted among 48 stroke patients in Medicine & Neuromedicine department of Mymensingh Medical College & Hospital. The objective of the study was to reveal the risk factors and other relevant information & immediate outcome of stroke patients. The sample size was 48 who ...
Mishina Masahiro - - 2008
Free radicals are known to activate coagulation and inhibit fibrinolysis. Edaravone, a free radical scavenger, protects vascular endothelial cells and neurons during acute brain ischemia in in vitro models. Hemorrhagic transformation and treatment outcomes were retrospectively examined in 76 patients with acute cardiogenic embolism treated with edaravone in addition to ...
Semplicini A - - 2008
BACKGROUND AND AIMS: Thrombolytic therapy with intravenous recombinant tissue plasminogen activator (rt-PA) improves outcome in patients with ischaemic stroke treated within 3 h of symptom onset, but its extended implementation is limited. A pilot study was designed to verify whether evaluation of patients with acute ischaemic stroke and their treatment ...
Prokopenko S V - - 2008
A specially developed proprioceptive correction costume was used for the restoration of motor functions in the proximal parts of the upper limb in central paralysis syndrome in patients in the late recovery and residual post-stroke states. The costume is a logical continuation of the Adeli and Gravistat proprioceptive correction systems, ...
Weimar C - - 2008
BACKGROUND: Risk stratification can contribute to individualised optimal secondary prevention in patients with cerebrovascular disease. OBJECTIVE: To prospectively investigate the prediction of the Essen Stroke Risk Score (ESRS) and a pathological Ankle Brachial Index (ABI) in consecutive patients hospitalised with acute ischaemic stroke or transient ischaemic attack (TIA) in 85 ...
Mehdi Nematbakhsh; Department of ...
BACKGROUND: The role of Nitric Oxide (NO) and its metabolites in stroke has been examined clinically and experimentally. The relationship between plasma NO level and Lesion Size (LS) or clinical severity of stroke is still under investigation. In this clinical study, the serum level of Nitrite (NI); the last metabolite ...
Peters Nils - - 2008
BACKGROUND: Mutations in the Notch3 gene are the cause of CADASIL, a hereditary small vessel disease leading to stroke and vascular dementia. The disease is characterized by ultrastructural granular deposits within small arterial vessels and degeneration of vascular smooth muscle cells. Yet, little is known about endothelial function in CADASIL. ...
Delgado-Mederos R - - 2008
OBJECTIVE: To evaluate the impact of early blood pressure (BP) changes on diffusion-weighted imaging (DWI) lesion evolution and clinical outcome in patients with stroke treated with IV tissue plasminogen activator (tPA). METHODS: We prospectively evaluated 80 patients with stroke with a documented middle cerebral artery occlusion treated with IV tPA. ...
Newman-Toker David E - - 2008
OBJECTIVE: To test the diagnostic accuracy of the horizontal head impulse test (h-HIT) of vestibulo-ocular reflex (VOR) function in distinguishing acute peripheral vestibulopathy (APV) from stroke. Most patients with acute vertigo, nausea/vomiting, and unsteady gait have benign APV (vestibular neuritis or labyrinthitis) as a cause. However, some harbor life-threatening brainstem ...
Montaner Joan - - 2008
BACKGROUND AND PURPOSE: Because there is no biologic marker offering precise information about stroke etiology, many patients receive a diagnosis of undetermined stroke even after all available diagnostic tests are done, precluding correct treatment. METHODS: To examine the diagnostic value of a panel of biochemical markers to differentiate stroke etiologies, ...
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