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Gündüz Ayşegül A Department of Neurology, Cerrahpasa School of Medicine, Istanbul University. Electronic address: - - 2014
Abnormal enhancement of polysynaptic brainstem reflexes has been previously reported in patients with spinal cord injury (SCI). We aimed to investigate trigemino-cervical reflex (TCR) in SCI since it may reflect alterations in the connections of trigeminal proprioceptive system and cervical motoneurons. Consecutive 14 patients with SCI and 16 healthy subjects ...
van Wanrooij R L J RL Department of Gastroenterology and Hepatology, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands, - - 2014
Different strategies have been developed to identify those refractory celiac disease (RCD) patients who are at risk to develop an enteropathy associated T-cell lymphoma (EATL). Flow cytometric analysis of intra-epithelial lymphocytes (IEL) with an aberrant phenotype is considered the golden standard but is not widely available. Immunohistochemistry (IHC) and T-cell ...
Kızıltan Meral E ME Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, Istanbul, - - 2014
Our aim was to investigate the extent and pattern of involved pathways using brainstem and spinal reflexes by comparing primary progressive freezing of gait (PPFOG) progressive supranuclear palsy (PSP) with FOG. Seven patients with PPFOG and age and sex matched seven PSP patients and 16 healthy subjects were included in ...
Zou H-Y HY Clinical Laboratory Diagnostics Center, Urumqi General Hospital of Lanzhou Military Command Area, Urumqi, China - - 2014
The aim of this study was to investigate the characteristics and polymorphisms of the T-cell receptor BV complementarity-determining region 3 (TCR BV CDR3) gene in peripheral blood mononuclear cells (PBMCs) from patients with uveitis to provide an experimental basis for studying the pathogenesis of this disease. RT-PCR amplification of 26 ...
Segal Lee S LS Division of Pediatric Orthopaedics, Phoenix Children's Hospital, 1919 East Thomas Road, Phoenix, AZ 85016 - - 2013
Patients with lipomyelomeningocele (LMMC) represent a unique population within the spectrum of spinal dysraphism. The natural history of LMMC remains poorly defined. The description and prevalence of the presenting orthopaedic clinical signs and symptoms for LMMC have been infrequent and often documented only in general terms. The goal of this ...
Morgan Richard A RA Surgery Branch, National Cancer Institute, Bethesda, MD 20892, USA. - - 2013
Nine cancer patients were treated with adoptive cell therapy using autologous anti-MAGE-A3 T-cell receptors (TCR)-engineered T cells. Five patients experienced clinical regression of their cancers including 2 on-going responders. Beginning 1-2 days postinfusion, 3 patients (#'s 5, 7, and 8) experienced mental status changes, and 2 patients (5 and 8) ...
Tisell Anders - - 2013
In Multiple Sclerosis (MS) the relationship between disease process in normal-appearing white matter (NAWM) and the development of white matter lesions is not well understood. In this study we used single voxel proton 'Quantitative Magnetic Resonance Spectroscopy' (qMRS) to characterize the NAWM and thalamus both in atypical 'Clinically Definite MS' ...
Zycinska K - - 2013
Autoimmune disease such as systemic lupus erythematosus or rheumatoid arthritis are connected with higher risk of atherosclerosis and cardiovascular complications and mortality. This results from inflammatory damage to the vessel wall by vasculitis. The aim of the present study was to evaluate whether patients with Wegener's granulomatosis (WG) and pulmonary ...
Veselinovic M - - 2012
Background: Cardiovascular (CV) morbidity and mortality are increased in patients with rheumatoid arthritis (RA). Our study aim was to determine the relationship between carotid artery intima-media wall thickness (IMT) and flow-mediated endothelium-dependent vasodilatation (FMD) in a patients with RA, in context with clinical and laboratory measurements. Patients and methods: Fifty-two ...
Jung San - - 2012
In spite of higher incidence of stroke in end-stage renal disease (ESRD) patients compared to general population, the risk factor for stroke which is specific to ESRD is not fully understood. The ESRD patients who develop stroke may have certain additional risk factors compared to ESRD patients without stroke. We ...
Yazdandoust Shima - - 2012
Serum small dense low-density lipoprotein (sd-LDL) concentrations were measured in patients with angiographically defined coronary artery disease (CAD) and compared to concentrations in healthy subjects. Five hundred and seventy patients with stable CAD were divided into CAD- and CAD+ based on angiography. Patients in whom stenosis was <50 % in diameter ...
Yuasa-Kawase Miyako - - 2012
Aim: Remnant lipoproteins are atherogenic and are accumulated in patients with type III hyperlipidemia (HL). Although type III HL is diagnosed by phenotyping apolipoprotein (apo) E, this procedure is time-consuming and inconvenient for routine clinical use. Clinical indices for screening type III HL in untreated HL patients have been proposed; ...
do Sameiro Faria Maria - - 2012
Abstract Objective. The aim of this study was to evaluate the association of tissue-type plasminogen activator (t-PA) levels with clinical data of patients under haemodialysis (HD) and with several variables potentially related to endothelial function and dysfunction. Material and methods. In a cross-sectional study involving 189 Portuguese HD patients, circulating ...
Ribeiro Camila Ferrari - - 2012
Nailfold capillaroscopy is a useful technique for evaluating changes in microcirculation. To investigate changes at nailfold capillaroscopy in psoriatic patients compared with controls. Nailfold capillaroscopy was performed in 46 psoriatic patients and 50 controls to assess microscopic morphological changes, capillary density and the presence of areas with devascularization. Patients with ...
Watanabe Renato - - 2012
Coronary artery calcification (CAC) and low bone density are coexisting deleterious conditions commonly shared by chronic kidney disease (CKD) patients. In the present study, we aimed to investigate whether the progression of CAC was associated with overtime reduction in bone density in non-dialyzed CKD patients. Methods: This is a prospective ...
Pereira Ivânio Alves IA Universidade do Sul de Santa Catarina, Florianópolis, SC, Brazil. - - 2012
To elaborate recommendations of the Rheumatoid Arthritis Committee of the Brazilian Society of Rheumatology (SBR) to manage comorbidities in rheumatoid arthritis (RA). To review the literature and the opinions of the SBR RA Committee experts. 1) Early diagnosis and proper treatment of comorbidities are recommended; 2) The specific treatment of ...
Haussen Diogo C - - 2012
BACKGROUND AND PURPOSE: Statins have been associated with increased risk of intracerebral hemorrhage (ICH), particularly in elderly patients with previous ICH. Recurrent ICH in the elderly is often related to cerebral amyloid angiopathy. Therefore, we investigated whether statin use is associated with increased prevalence and severity of microbleeds (MB), particularly ...
Charitos Efstratios I - - 2012
BACKGROUND: Intermittent rhythm monitoring (IRM) to detect atrial fibrillation (AF) recurrence is employed to evaluate the success of therapeutic interventions. In a large population of continuously monitored (CM) patients, we investigated the sensitivity of various frequency and duration IRM strategies on the detection of AF recurrence, the dynamics behind AF ...
Pereg David - - 2012
Peripheral arterial disease (PAD) is a strong risk factor for cardiovascular morbidity and mortality. Therefore, target low-density lipoprotein (LDL) cholesterol level in patients with PAD is ≤70 mg/dl, similar to patients with coronary artery disease (CAD). However, despite their high cardiovascular risk, patients with PAD less frequently achieve LDL cholesterol ...
Opolski Grzegorz - - 2012
INTRODUCTION Diabetes mellitus (DM) and coronary artery disease (CAD) are associated with increased cardiovascular risk.  OBJECTIVES To compare management of high-risk patients with DM and patients with CAD in Poland.  PATIENTS AND METHODS Randomly selected primary care offices enrolled patients aged ≥ 55 years, with DM and no documented CAD (n=210), or with ...
Pawlak Krystyna - - 2012
OBJECTIVE: To investigate the role of autoantibodies against oxidized LDL (oxLDL-Ab) in clearing of oxLDL from circulation in dialyzed uremic patients, as well as the significance of this process in the carotid atherosclerosis and cardiovascular complications. METHODS: oxLDL, oxLDL-Ab and intima-media thickness (IMT) were measured in 132 uremic patients on ...
Darchini-Maragheh Emadodin - - 2012
Delayed neurotoxic complications of chemical warfare agents (CWA) such as sulphur mustard (SM) and tabun in human beings have not been reported in detail. We thus aimed to investigate possible neurotoxic complications of these agents in Iranian veterans 22-27 years after exposure. Following coordination with the veteran foundation and obtaining ...
Lai Hoang M - - 2012
To investigate differences between outpatients with progressive and nonprogressive coronary artery disease (CAD) measured by coronary angiography. Chart reviews were performed in patients in an outpatient cardiology practice having ≥ 2 coronary angiographies ≥ 1 year apart. Progressive CAD was defined as 1) new non-obstructive or obstructive CAD in a ...
Kharrat Ines - - 2012
Background: Chronic kidney failure is associated with dyslipidemia and accelerated atherosclerosis. Aim: To study lipidic metabolism alterations in patients with chronic kidney failure on hemodialysis. Methods: The study interested 45 hemodialysis patients with a mean age of 49.04 ±15.92 years old and 45 healthy controls. A blood sample was collected ...
Knowlton N N Oklahoma Medical Research Foundation, Oklahoma City, OK, USA. - - 2012
The purpose of this study was to explore whether nontraditional risk factors, such as apolipoprotein C-III (Apo C-III) and its corresponding Apo B lipoprotein (Lp) subclasses, contribute to the risk of cardiovascular disease in rheumatoid arthritis (RA) patients. Apolipoprotein and lipoproteins were measured in 152 RA patients by immunoturbidimetric procedures, ...
Peralta Lígia - - 2012
Trichotillomania (TTM) is an impulse-control disorder, in which patients chronically pull hair from the scalp and/or other sites. We herein report a 8-year-old male patient who developed TTM in the classical tonsure pattern ("Friar Tuck" sign). The diagnosis was confirmed by trichoscopy, which showed decreased hair density, broken hairs with ...
Zagura Maksim - - 2012
Arterial stiffness is an independent predictor of vascular morbidity and mortality in patients with atherosclerosis. Angiographic score (ASc) reflects severity of atherosclerosis in patients with peripheral arterial disease (PAD). Osteopontin (OPN) and oxidized low-density lipoprotein (oxLDL) are involved in the pathogenesis of atherosclerosis. The aim of the present study was ...
Tajika Kenichiro - - 2012
Background: The association between elevated malondialdehyde-modified low-density lipoprotein (MDA-LDL) and plaque instability in patients with coronary artery disease (CAD) is suspected but not established. The aim of the present study was therefore to investigate the association between serum MDA-LDL and plaque characteristics on angioscopy. Methods and Results: A total of 37 consecutive ...
Zeng Ting - - 2012
OBJECTIVES: To investigate the prevalence of autoantibodies against ATP-binding cassette transporter A1 (ABCA1) in SLE patients, and evaluate the association between anti-ABCA1 autoantibodies and atherosclerosis in SLE. DESIGN AND METHOD: The sera of 75 SLE patients and 75 healthy controls were tested by immunoblotting. Then, we examined the effect of ...
Bentsen H - - 2012
BACKGROUND: Polyunsaturated fatty acids (PUFAs) are bimodally distributed in acute schizophrenia, suggesting two endophenotypes. We intended to characterize these endophenotypes clinically. Our a priori hypothesis was that low PUFA patients have more negative symptoms. PATIENTS AND METHODS: Patients (aged 18-39) with schizophrenia, schizoaffective or schizophreniform disorders were recruited at hospital ...
Utriainen Karri T - - 2012
Patients needing surgery for peripheral arterial disease (PAD) represent a severe form of atherosclerosis with an overall five-year mortality of 30 % after revascularisation. The aetiology for poor postoperative clinical outcome in these high-risk patients is not fully established. Obstructive sleep apnoea (OSA) is associated with atherosclerosis and is an ...
Eleftheriadis Theodoros - - 2012
Perilipin-1 surrounds lipid droplets in both adipocytes and in atheroma plaque foam cells and controls access of lipases to the lipid core. In hemodialysis (HD) patients, dyslipidemia, malnutrition, inflammation and atherosclerosis are common. Thirty-six HD patients and 28 healthy volunteers were enrolled into the study. Ten HD patients suffered from ...
Lopez-Huertas Eduardo - - 2012
Metabolic syndrome (MS) is characterised by accumulation of CVD risk factors. The use of very long chain n-3 polyunsaturated fatty acids (VLC n3 PUFA) could potentially benefit MS by reducing risk factors. To better understand the possible VLC n3 PUFA benefits, the literature was systematically reviewed for randomised controlled trials ...
Machal Jan - - 2012
The impact of ApoE polymorphism on angiographic parameters was assessed in patients referred for coronary angiography. Elective coronary angiography was performed in 671 subjects (525 men, 146 women, mean age 60 ± 10 years) with symptoms of ischemic heart disease. The patients were divided into: no CAD group (smooth coronary ...
Jung Ka Won - - 2012
The coexistence of carotid atherosclerosis in ischemic stroke patients with small-vessel disease (SVD) or intracranial large-vessel disease (ICLVD) was investigated using carotid duplex ultrasonography, and whether its coexistence affected the clinical prognosis was determined. Ischemic stroke patients with SVD or ICLVD were enrolled (n=103). Risk factors, demographic data, and National ...
Motawi Tarek - - 2012
This study aimed to investigate the association of both intercellular adhesion molecule-1 (ICAM-1) and endothelial cell adhesion molecule (E-selectin) polymorphisms using PCR technique and their role in the pathogenesis of atherosclerosis. The study enrolled 285 individuals, classified into 4 groups: 63 cerebrovascular atherosclerotic patients, 75 cardiovascular patients, 72 peripheral atherosclerotic ...
Scardina Giuseppe Alessandro GA Department of Surgery and Oncology, Section of Oral Sciences, University of Palermo, Palermo, Italy. - - 2012
Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The ...
Asamiya Y - - 2012
BACKGROUND AND AIMS: Serum malondialdehyde-modified low-density lipoprotein (MDA-LDL) and MDA-LDL/LDL-cholesterol (LDL-c) ratio are risk factors for arteriosclerosis and cardiovascular disease (CVD). However, no information is available on these parameters or their associations with coronary artery calcification (CAC) in haemodialysis (HD) patients. METHODS AND RESULTS: Fifty-seven HD patients and 26 control ...
Tektaş Ayşegül Korkmaz - - 2012
Lipoprotein-associated phospholipase A2 (Lp-PLA2) and arginase are recently described inflammatory biomarkers associated with cardiovascular disease. In this study, we aimed to investigate the possible effects of serum Lp-PLA2 mass levels on arginase/nitric oxide (NO) pathway as a cardiovascular risk marker in hemodialysis (HD) patients. Forty-three HD patients and 15 healthy ...
Matsuo Yoshiki - - 2012
AIMS: The importance of oxidized low-density lipoprotein (oxLDL) has been implicated in the process of plaque rupture. However, few previous studies demonstrated the relationship between plaque morphology and oxLDL. We evaluated the relationship between coronary plaque vulnerability assessed by optical coherence tomography (OCT) and circulating malondialdehyde-modified low-density lipoprotein (MDA-LDL). METHODS ...
Niccoli Giampaolo - - 2012
OBJECTIVE: Low density lipoproteins (LDL) with an electronegative charge [LDL(-)] may cause endothelial injury. We assessed the association between serum LDL(-) levels and coronary artery disease (CAD) severity. METHODS: We prospectively enrolled patients with CAD angiographic evidence [stable angina (SA) or non-ST-elevation-acute coronary syndrome (NSTE-ACS)], or with normal coronary arteries ...
Cooper Dennis L - - 2012
Background: Granulocyte Colony-Stimulating Factor (G-CSF) alone or in conjunction with chemotherapy is commonly used to mobilize hematopoietic progenitor cells (HPC) into peripheral blood for progenitor cell harvest for autologous HPC transplantation. However, in up to 30% of patients, HPC are not effectively mobilized. In this study, we report the efficacy ...
Miyaki Akira - - 2012
PURPOSE: We aimed at investigating the efficacy of multidetector computed tomography (MDCT) angiogram reconstructed using the maximum intensity projection (MIP) technique for the assessment of perigastric vascular anatomy before laparoscopy-assisted gastrectomy (LAG) for gastric cancer. METHODS: Seventy-one patients who underwent LAG were enrolled in the study. Contrast-enhanced scans of the ...
Eren Zehra - - 2012
Introduction. Human paraoxonase 1 (PON1) is an enzyme related with high-density lipoprotein cholesterol. The link between genetic polymorphisms of PON1 and hyperlipidemia and increased lipid oxidation may explain these complications in the course of glomerular diseases. In this study, we aimed to investigate PON1 192 and PON1 55 polymorphisms in ...
Kataoka Yu - - 2012
The purpose of this study was to determine atheroma progression in patients with spotty calcification. Although extensively calcified atherosclerotic lesions have been proposed to be clinically quiescent, the presence of spotty calcification within plaque has been reported to be associated with an increased incidence of ischemic cardiovascular events. The relationship ...
Tayyebi-Khosroshahi Hamid - - 2012
C-reactive protein (CRP), a strong independent risk marker of cardiovascular disease (CVD), and tumor necrosis factor-alfa (TNF-α), a known pro-inflammatory cytokine, are elevated and have damaging effects in patients with chronic renal failure (CRF). Omega-3 fatty acids play an important modulatory role in inflammatory responses. The aim of this study ...
Camacho-Alonso Fabio - - 2012
The aim of this study was to analyze fungiform papillae density in patients with burning mouth syndrome (BMS) and xerostomia. In this cross-sectional clinical study, sixty patients were included (20 with BMS, 20 with xerostomia and 20 healthy controls). The fungiform papillae density was analyzed over a small region on ...
Sinha Nakul N Sahara India Medical Institute, Lucknow, Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. - - 2012
The aims of the study were to ascertain difference in lipid levels of 'Young' onset of coronary artery disease (CAD) (≤ 45 years) vs. 'Not so Young' onset of CAD (≥ 55 years) among north Indians and also to investigate determinants of 'dyslipidaemia' in CAD patients. This was a prospective, ...
Schröder J - - 2012
BACKGROUND: The aim of this study was to investigate factors influencing mortality after percutaneous coronary intervention (PCI) in patients aged ≥ 75 years compared to younger patients. PATIENTS AND METHODS: A total of 1,809 coronary heart disease (CHD) patients after PCI with stent implantation in our hospital were assessed. Kaplan-Meier analyses with ...
Beniczky Simona Alexandra - - 2012
There is considerable evidence suggesting, that older antiepileptic drugs (AEDs) and some of the newer ones decrease bone mineral density (BMD). However, there is only limited and conflicting data concerning the effect of levetiracetam on BMD. In this cross-sectional study we analysed data from 168 adult consecutive outpatients treated with ...
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