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Jeon Byoung Seung - - 2013
Clostridium sp. BS-1 produces hexanoic acid as a metabolite using galactitol and enhanced hexanoic acid production was obtained by in situ extractive fermentation with Clostridium sp. BS-1 under an optimized medium composition. For medium optimization, five ingredients were selected as variables, and among them yeast extract, tryptone, and sodium butyrate ...
Duchowicz Pablo R - - 2013
Quantitative structure-property relationships (QSPRs) were applied to the aminograms obtained by HPLC in our laboratories for Torrontés and Merlot wines. Dragon theoretical descriptors were derived for a set of optimized amino acid structures with the purpose of establishing QSPR models. The statistical Replacement Method was used for designing the best ...
Meena Laxman S - - 2013
Abstract Tuberculostearic acid (l0-methylstearic acid, TSA) is a major constituent of mycobacterial membrane phospholipids and its biosynthesis involves direct methylation of oleic acid esterified as a component of phospholipids. Methyltransferases of mycobacteria were long proposed to be involved in the synthesis of methyl-branched short chain fatty acids, but direct experimental ...
Parsons Thomas B - - 2013
The first synthesis of kottamide E, a marine natural product containing a 5,6-dibromindole linked via a (Z)-enamide to an unusual 1,2-dithiolane-containing amino acid, is reported.
Udut V V - - 2013
Phospholipid hepatoprotectors essentiale, eplir, and their combinations with succinic acid decreased the relative content of apoptotic lymphocytes and granulocytes in the blood, content of TNF-α, total and indirect bilirubin, and activities of transaminases and alkaline phosphatase and increase the content of IL-10 in rats with experimental intoxication induced by isoniazid ...
Wardhani Dyah H - - 2013
Fermentation by using Aspergillus oryzae has been reported to increase antioxidant activity of soybeans significantly. The effectiveness of the extract from fermented soybeans was studied in 3 model foods with different complexities, i.e., linoleic acid emulsion, sunflower oil emulsions and bulk sunflower oil. For the emulsion systems, oxidation at two ...
Khalkar Sharmishtha - - 2013
Anhydride copolymers were synthesized from acrylic acid and fatty alcohols (C12- C18, C18:1). These n-alkyl acrylates were treated with maleic anhydride in presence of hydrogen peroxide in second step, to form anhydride copolymer. The anhydride copolymer further reacted to n-butylamine to form poly (n-acrylate-co-nbutylmalemide). The compounds were used as pour ...
Ferreira Luciana Garros - - 2013
The rationale of the present review is to analize the activity of Rosmarinus officinalis in the the cardiovascular system A MEDLINE database search (from January 1970 to December 2011) using only rosmarinic acid as searched term. The references search revealed 509 references about rosmarinic acid in 40 years (the first ...
Mar Win Win - - 2013
Propylsulfonic acid-functionalized mesoporous silica SBA-15 has been synthesized via one-step strategy at 130°C based on the co-condensation of TEOS and MPTMS in the presence of Pluronic 123 polymer and H2O2 in HCl aqueous solution. The synthesized solid exhibited hydrothermal stability in boiling water without significant change in textural properties. The ...
Suárez-Díaz Edna - - 2013
This paper builds upon Hans-Jörg Rheinberger ideas on the oscillation and intercalation of epistemic things and technical objects in experimental systems, to give a fine-grained analysis of what here is called the problems of "adaptation" between our material and cognitive tools and the phenomena of the material world. To do ...
Chang Chin-Feng - - 2013
The objectives of this work were to isolate and characterize the polyhydroxyalkanoate (PHA) producing bacteria in enriched piggery sludge and make methyl esters from PHA for industrial applications. The strain ECAe24 isolated from piggery sludge with the highest PHA production was selected to produce PHA and then methyl ester by ...
Kasaai Mohammad Reza - - 2013
Fragmentation of chitosan in aqueous solution by hydrochloric acid was investigated. The kinetics of fragmentation, the number of chain scissions, and polydispersity of the fragments were followed by viscometry and size exclusion chromatography. The chemical structure and the degree of N-acetylation (DA) of the original chitosan and its fragments were ...
de Freitas Alves Claudiney C Laboratório de ImunoFarmacologia Experimental (LIFE), Departamento de Clínica Médica, Instituto de Ciências da Saúde, Universidade Federal do Triângulo Mineiro (UFTM), Rua Manoel Carlos 162, 38025-380 Uberaba, MG, - - 2013
Asthma is a disease of airway inflammation characterized by airway hyperresponsiveness, eosinophilic inflammation, and hypersecretion of mucus. Ellagic acid, a compound derived from medicinal plants and fruits, has shown anti-inflammatory activity in several experimental disease models. We used the classical experimental model, in BALB/c mice, of sensibilization with ovalbumin to ...
Cárdenas-Rodríguez Noemí N Laboratory of Neurochemistry, National Institute of Pediatrics, 04530 DF, - - 2013
It is estimated that at least 100 million people worldwide will suffer from epilepsy at some point in their lives. This neurological disorder induces brain death due to the excessive liberation of glutamate, which activates the postsynaptic N-methyl-D-aspartic acid (NMDA) receptors, which in turn cause the reuptake of intracellular calcium ...
Arshad Muhammad Sajid MS National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan. - - 2013
Lipid peroxidation is the cause of declining the meat quality. Natural antioxidants plays a vital role in enhancing the stability and quality of meat. The supplementation of natural antioxidants in feed decreases lipid peroxidation and improves the stability of meat. The present research was conducted to determine the effect of ...
Wang Lin L Computational Biophysics and bioinformatics, Department of Physics, Clemson University, Clemson, SC 29634, - - 2013
Many molecular events are associated with small or large conformational changes occurring in the corresponding proteins. Modeling such changes is a challenge and requires significant amount of computing time. From point of view of electrostatics, these changes can be viewed as a reorganization of local charges and dipoles in response ...
Orange François - - 2012
Identification of the earliest traces of life is made difficult by the scarcity of the preserved microbial remains and by the alteration and potential contamination of the organic matter (OM) content of rocks. These factors can confuse interpretations of the biogenicity and syngenicity of fossilised structures and organic molecules found ...
Alonso Rocío - - 2012
Hispánico cheese, manufactured from a mixture of cow and ewe milk, is representative of cheese varieties made using milk from more than one animal species in Mediterranean countries. The shortage of ewe milk production in autumn hinders the uniformity of Hispánico cheese composition throughout the year. To surmount this inconvenience ...
Pulido Angeles - - 2012
The ketonic decarboxylation of carboxylic acids has been carried out experimentally and studied theoretically by DFT calculations. In the experiments, monoclinic zirconia was identified as a good catalyst, giving high activity and high selectivity when compared with other potential catalysts, such as silica, alumina, or ceria. It was also shown ...
Watanabe Masanori - - 2012
A newly isolated lactic acid producing bacterium Lactobacillus rhamnosus M-23, from a rice washing drainage storage tank was found to produce l-(+)-lactic acid from a non-sterilized mixture of rice washing drainage and rice bran without any additions of nutrients under the simultaneous saccharification and fermentation (SSF) process. The maximum lactate ...
Zhao Yue - - 2012
Surfactin in methanol solution with acid would be spontaneously esterified into the mono- or dimethyl ester surfactin even at a temperature as low as 4 °C because there were two free carboxyl groups in the peptide loop of surfactin. Using trifluoroacetic acid as the catalyst, the esterification and the contents change ...
Zhang D S - - 2012
SPORL (Sulfite Pretreatment to Overcome Recalcitrance of Lignocellulose) pretreatment was applied to switchgrass and optimized through an experimental design using Response Surface Methodology within the range of temperature (163-197°C), time (3-37min), sulfuric acid dosage (0.8-4.2% on switchgrass), and sodium sulfite dosage (0.6-7.4% on switchgrass). Performance of SPORL was compared with ...
Olaifa Folashade - - 2012
Experiments were performed to investigate the effect of ascorbic acid in reducing haemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season. Six experimental donkeys administered orally with ascorbic acid (200 mg/kg), and six control donkeys, not administered with ascorbic acid, were subjected to packing. Blood samples were collected from ...
Wang Xianxiang - - 2012
A simple fluorescence sensor for sensitive turn-off detection of ascorbic acid (AA) was developed by using protein-modified Au nanoclusters in aqueous media. The sensing mechanism is originated from the oxidation state change of Au nanoclusters controlled by AA. Under optimal experimental conditions, a good linear relationship between the relative fluorescence ...
He Rui - - 2012
Functional screening based on the antibacterial activity of a metagenomic library of the Japanese marine sponge, Discodermia calyx, afforded three β-hydroxyl fatty acids: 3-hydroxypalmitic acid, 3-hydroxylauric acid and 3-hydroxymyristic acid, heterologously expressed in an antibacterial clone, pDC113. 3-Hydroxypalmitic acid showed moderate antibacterial activity against Bacillus cereus and Candida albicans. A ...
Diamantis Vasileios - - 2012
Biohydrogen production from a simulated fruit wastewater (soluble COD = 3.17 ± 0.10 g L(-1)) was carried out in a continuous stirred tank reactor (CSTR) of 2 L operational volume without biomass inoculation, heat pre-treatment or pH adjustment, resulting in a low operational pH (3.75 ± 0.09). The hydraulic retention time (HRT) varied from 15 to 5 h. A strong ...
Panda Siva S - - 2012
Unprotected S-acylated cysteine isopeptides containing α-, β- or γ-amino acid units have been synthesized and their conversion to native hexapeptides by S- to the N- terminus ligations involving 17-, 18- and 19-membered cyclic transition states have been demonstrated both experimentally and computationally to be more favorable than intermolecular cross-ligations. © ...
Li Yinping - - 2012
A novel fluorescence assay system for glucose was developed with thioglycollic acid (TGA)-capped CdTe quantum dots (QDs) as probes. The luminescence quantum yield of the TGA-capped CdTe QDs was highly sensitive to H(2) O(2) and pH. In the presence of glucose oxidase, glucose is oxidized to yield, gluconic acid and ...
Durán Raúl V - - 2012
The cellular response to amino acids is controlled at the molecular level by TORC1. While many of the elements that participate in TORC1 signaling are known, we still have no clear idea how cells sense amino acids. Two recent studies found that leucyl-tRNA synthetase (LRS) is a leucine sensor for ...
Sloboda Natacha - - 2012
To analyze age-related interactions between obesity, its associated metabolic disorders, and macrocirculation, we studied large artery stiffness and fatty acid responsiveness in lean and obese Zucker rats, aged 25 (adult) and 80 weeks (very old). Systolic arterial pressure was higher in old obese than in old lean rats (178 ± ...
Boddaert Thomas - - 2012
(1)H NMR studies quantify the abilities of achiral amino acids to communicate a left-handed screw-sense preference from one helical Aib(4) domain to another: certain quaternary amino acids (e.g. Ac(6)c) act as effective conductors of conformational preference while others (e.g. diphenylglycine) acts as insulators.
Banz William J - - 2012
We have previously reported that the synthetic estrogen, (+)-Z-bisdehydrodoisynolic Acid [(+)-Z-BDDA], attenuated weight gain and cardiovascular risk in obese rodents. To determine if these antiobesity effects were attributed to changes in basal metabolism, we assessed indirect calorimetry and metabolic profile in female obese Zucker (OZR) rats provided (+)-Z-BDDA (0.0002% food ...
Zagórska Agnieszka - - 2012
Affinities of arylpiperazinylalkyl derivatives of imidazo[2,1-f]purine-2,4-dione and imidazolidine-2,4-dione for serotonin transporter and their acid-base properties were evaluated. The dissociation constant (pK(a)) of compounds 1-22 were determinated by potentiometric titration and calculated using pKalc 3.1 module of the Pallas system. The data from experimental methods and computational calculations were compared and ...
Dinç Saliha S Çumra Vocational High School, Selçuk University, Konya, 42500 - - 2014
The effects of zero-trans chemically interesterified (in-es) and non-interesterified (non-in-es) cottonseed (CO), hazelnut (HO) and olive oil (OO) and their blends (25, 50 and 75%) with palm oil (PO) were studied in the production of cookies. All the experimental shortenings had zero-trans fatty acids (TFA) while the shortening contained 14.20% ...
Kucki Melanie - - 2012
The incorporation of rhodamine dyes in the cell wall of diatoms Coscinodiscus granii and Coscinodiscus wailesii for the production of luminescent hybrid nanostructures is investigated. By systematic variation of the substitution pattern of the rhodamine core, we found that carbonic acids are considerably better suited than esters because of their ...
May David - - 2011
Topical metronidazole and azelaic acid are equally effective for the papulopustular lesions of acne rosacea, although metronidazole is better tolerated. Oral doxycycline, tetracycline, and metronidazole are also effective, but not enough evidence exists to determine whether one is more effective than another or more effective than topical therapy.
Kuratsu Masahiro - - 2010
We performed analyses of the phenotypic and genotypic relationships focusing on biosyntheses of amino acids, purine/pyrimidines, and cofactors in three Lactobacillus strains. We found that Lactobacillus fermentum IFO 3956 perhaps synthesized para-aminobenzoate (PABA), an intermediate of folic acid biosynthesis, by an alternative pathway.
Garanin Evgeny M - - 2010
Upon heating in a dry atmosphere, benzenehexasulfonic acid forms three cyclic anhydrides. Mono- and dianhydride do not hydrolyze readily due their flatter structures compared to the hydrolysis products. The trianhydride appears more to be reactive toward hydrolysis. In solutions, the mono- and dianhydride undergo ring-shift tautomerization, which is in the ...
Gajera H P - - 2010
Biscuits prepared with different levels of hydrogenated fat (vanaspati) and peanut (Arachis hypogaea L.) butter (PB) (100:00, 75:25, 50;50, 25;75, 00:100) were evaluated for their fatty acid composition and textural property. Saturated fatty acids like myristic, palmitic, stearic acids were higher in control biscuits (100% vanaspati), which decreased with increasing ...
von Vietinghoff Sibylle - - 2010
Mycophenolic acid is a commonly used immunosuppressant after organ transplantation and in autoimmune diseases; however, myelosuppression is a major complication despite its largely favorable side-effect profile. Mycophenolic acid targets inosine monophosphate dehydrogenase, which is essential for T-cell proliferation. The T-cell cytokine interleukin-17 (IL-17 or IL-17A) and its receptor maintain normal ...
Young Cora J - - 2010
Perfluorocarboxylic acids (PFCAs) can be found from the hydrolysis of perfluoroacyl fluorides and chlorides, which can be produced in three separate ways in the atmosphere. Alternatively, PFCAs can be formed directly in the gas phase through reaction of perfluoroacyl peroxy radicals or perfluorinated aldehyde hydrates. All five mechanisms have been ...
Hiemstra Thomas F - - 2010
Despite advances in the treatment of vasculitis, modern therapies fail to induce or maintain remission in a significant proportion of patients. Mycophenolic acid is increasingly used to treat vasculitis syndromes. Here, we consider relevant pharmacokinetic and pharmacodynamic properties of mycophenolate, with emphasis on the impact of renal impairment, and we ...
Rupprecht Korbinian - - 2009
The influence of pantoprazole 40 mg twice daily on the bioavailability of a single dose of mycophenolate mofetil 1000 mg or enteric-coated mycophenolate sodium is investigated in healthy volunteers. The plasma concentrations of mycophenolic acid and of the inactive metabolite mycophenolic acid glucuronide are measured by high-performance liquid chromatography. The ...
Bell Stephen G - - 2010
CYP199A4 (RPB3613) from Rhodopseudomonas palustris HaA2 is a heme monooxygenase that catalyzes the hydroxylation of para-substituted benzoic acids. Monooxygenase activity of CYP199A4 can be reconstituted in a Class I electron transfer chain with an associated [2Fe-2S] ferredoxin, HaPux, (RPB3614) and the flavin-dependent reductase, HaPuR, (RPB3656) that is not associated with ...
Arslan-Alaton Idil - - 2009
H2O2/UV-C treatment of four commercially important aryl sulfonates (naphthalene sulfonic acids H-acid, K-acid, J-acid and benzene sulfonic acid Para base) in aqueous solutions was investigated. Photodegradation kinetics was followed in terms of changes brought about in the parent compound concentration via high performance liquid chromatography, as well as abatement of ...
Hahn V - - 2009
Unprotected L-phenylalanine was derivatized by an innovative enzymatic method by means of laccases from Pycnoporus cinnabarinus and Myceliophthora thermophila. During the incubation of L-phenylalanine with para-hydroquinones using laccase as biocatalyst, one or two main products were formed. Dependent on the substitution grade of the hydroquinones mono- and diaminated products were ...
Peneva Kalina - - 2008
Fluorescent probes are essential for the exploration of protein function, detection of molecular interactions, and conformational changes. The nitrilotriacetic acid derivatives of different chromophores were successfully used for site-selective noncovalent fluorescence labeling of histidine-tagged proteins. All of them, however, suffer from the same drawback--loss of the fluorescence upon binding of ...
Saadoun A - - 2008
Meat yields, proximate compositions, fatty acids compositions and technological parameters are reviewed for species which might be further developed as indigenous sources of meat in South America. These include the alpaca (Lama pacos), capybara (Hydrochoerus hydrochaeris), guanaco (Lama guanicoe), llama (Lama glama), nutria (Myocastor coypus), collared peccary (Tayassu tajacu), greater ...
Ogoshi Tomoki - - 2008
Condensation of 1,4-dimethoxybenzene (DMB) with paraformaldehyde in the presence of BF3.O(C2H5)2 gave novel para-bridged pentacyclic pillar DMB (DMpillar[5]arene). Moreover, para-bridged pentacyclic hydroquinone (pillar[5]arene) was prepared. Pillar[5]arene formed 1:1 host-guest complexes with dialkyl viologen and alkyl pyridinium derivatives. However, pillar[5]arene did not form complexes with the diadamantyl viologen derivative since a ...
Qureshi Ansa - - 2008
Myfortic is a new formulation of mycophenolic acid (MPA) utilizing enteric coated mycophenolate sodium (EC-MPS) that may have fewer gastrointestinal side effects.
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