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Wu Ya Y Key Laboratory of Applied Surface and Colloid Chemistry, MOE, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062 (P.R. China), Fax: - - 2014
A binary acid system has been developed that features an air-stable organometallic precursor, titanocene dichloride, and simple organic cooperative Brønsted acids, which allowed for mild and highly efficient Mannich reactions of both aryl and alkyl ketones with excellent yields and satisfactory diastereoselectivity. Mechanistic studies, including (1) H NMR titration, X-ray structure ...
Grosskinsky Dominik K DK University of Copenhagen, Dpt. of Plant and Environmental Sciences, Copenhagen Plant Science Centre, Taastrup, Denmark ; - - 2014
Phytohormones are known as essential regulators of plant defenses, with ethylene, jasmonic and salicylic acid as central immunity backbone, while other phytohormones have been demonstrated to interact with this. Only recently, a function of the classic phytohormone cytokinin in plant immunity has been described in Arabidopsis, rice and tobacco. Although ...
Vereshchagina Y V YV Institute of Biology and Soil Science, Far Eastern Branch of the Russian Academy of Sciences, 159 Stoletija Str., Vladivostok, 690022, - - 2014
Caffeoylquinic acids are found in artichokes, and they are currently considered important therapeutic or preventive agents for treating Alzheimer's disease and diabetes. We transformed artichoke [the cultivated cardoon or Cynara cardunculus var. altilis DC (Asteraceae)] with the rolC gene, which is a known inducer of secondary metabolism. High-performance liquid chromatography ...
Cengiz Fatma Pelin FP Kars State Hospital , Kars , Turkey - - 2014
Abstract Objective: Although there are several methods to treat Verruca plana, warts do not respond well to the common therapeutic options. In this study, we compared the safety and efficacy of 10% trichloroacetic acid, 25% trichloroacetic acid, and cryotherapy for the treatment of warts caused by Verruca plana. Methods: Ten ...
Crapeau Myriam M Universite Libre de Bruxelles (ULB), - - 2014
Gap1, the yeast general amino acid permease, is a convenient model for studying how the intracellular traffic of membrane transporters is regulated. Present at the plasma membrane under poor nitrogen supply conditions, it undergoes ubiquitylation, endocytosis, and degradation upon activation of the TORC1 kinase complex in response to an increase ...
Won Eun-Ji EJ Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 440-746, South - - 2014
Ultraviolet (UV) radiation can become an ecological problem due to its deleterious impact on organisms. To evaluate the effects of UV radiation on the reproductive physiology and macromolecules in marine zooplankton, several doses of UV radiation were used to treat the copepod Paracyclopina nana, and we analyzed in vivo endpoints ...
Fernandes Fabrício F A FF Programa de Pós-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas - Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, - - 2014
Serotherapy against snakebite is often unavailable in some regions over Brazil, where people make use of plants from folk medicine to deal with ophidic accidents. About 10% of Combretum species have some ethnopharmacological use, including treatment of snakebites. We evaluated the ability of the extract of Combretum leprosum and its ...
Ma Dongyun D National Engineering Research Center for Wheat, Henan Agricultural University, Zhengzhou, Henan, China, 450002; Key Laboratory of Physiology, Ecology and Genetic Improve of Food Crops in Henan Province, Zhengzhou, Henan, China, - - 2014
Understanding the variance of antioxidant in wheat grain responses to irrigation and nitrogen (N) fertilizer management will improve the nutrient quality of wheat grain. Four N rates (0, 180, 240, and 300 kg ha(-1) ) combined with irrigation times (I0 , no irrigation; I1 , jointing time irrigation; I2 , jointing + flowering time ...
Samimi Mansooreh M Department of Gynecology and Obstetrics, School of Medicine, Kashan University of Medical Sciences, Kashan, - - 2014
We are aware of no study that examined the effects of omega-3 fatty acid supplementation on insulin metabolism and lipid profiles in gestational diabetes (GDM). This study was designed to assess the effects of omega-3 fatty acid supplementation on insulin concentrations and lipid profiles among pregnant women with GDM. This ...
Kumar Manoj - - 2014
Density functional theory calculations predict that the gas-phase decomposition of carbonic acid, a high energy, 1,3-hydrogen atom transfer reaction, can be catalyzed by a monocarboxylic acid or a dicarboxylic acid, including carbonic acid itself. Carboxylic acids are found to be more effective catalysts than water. Among the carboxylic acids, the ...
Freund-Levi Yvonne Y Divisions of Clinical Geriatrics, Karolinska Institutet, Karolinska University Hospital at Huddinge, Stockholm, - - 2014
Background: Oxidative stress and inflammation are two key mechanisms suggested to be involved in the pathogenesis of Alzheimer's disease (AD). Omega-3 fatty acids (ω-3 FAs) found in fish and fish oil have several biological properties that may be beneficial in AD. However, they may also auto-oxidize and induce in vivo ...
Könczöl Arpád A Compound Profiling Laboratory, Gedeon Richter Plc., H-1475 Budapest, - - 2014
Oxybaphus nyctagineus (Michx.) Sweet has traditionally been used by several Native American tribes predominantly as a topical anti-inflammatory and analgesic agent. To evaluate the antioxidant, analgesic and anti-inflammatory activity of the extracts prepared from the aerial parts of O. nyctagineus and to characterize the major chemical constituents of the bioactive ...
Genovese Salvatore S Dipartimento di Farmacia, Università "G. d'Annunzio" Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, (CH), Italy, - - 2014
4'-Geranyloxyferulic (GOFA) and boropinic acid have been discovered during the last decade as interesting phytochemicals having valuable pharmacological effects as cancer chemopreventive, anti-inflammatory, neuroprotective, and anti-Helicobacter pylori agents. A reverse-phase HPLC-UV/Vis method for the separation and quantification of the title oxyprenylated ferulic acid derivatives in extracts obtained from peels of ...
Scheringer Martin M Institute for Chemical and Bioengineering, ETH Zürich, 8093 Zürich, Switzerland. Electronic address: - - 2014
In this discussion paper, the transition from long-chain poly- and perfluorinated alkyl substances (PFASs) to fluorinated alternatives is addressed. Long-chain PFASs include perfluoroalkyl carboxylic acids (PFCAs) with 7 or more perfluorinated carbons, perfluoroalkyl sulfonic acids (PFSAs) with 6 or more perfluorinated carbons, and their precursors. Because long-chain PFASs have been ...
Bellido Carolina C Department of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, - - 2014
ABE fermentation by Clostridium beijerinckii of steam-exploded and ozonated wheat straw hydrolysates was investigated. In steam-exploded hydrolysates, highest yields of 0.40g/g ABE yield and 127.71gABE/kg wheat straw were achieved when the whole slurry from the pretreatment was used. In ozonated hydrolysates, 0.32g/g ABE yield and 79.65gABE/kg wheat straw were obtained ...
Hassanzadeh Salman S Department of Fibre and Polymer Technology, School of Chemical Science and Engineering, KTH Royal Institute of Technology, SE-100 44 Stockholm, Sweden. Electronic address: - - 2014
Exceptionally high cellulose liquefaction yields, up to 87% as calculated from the amount of solid residue, were obtained under mild conditions by utilizing the synergistic effect of microwave radiation and acid catalysis. The effect of processing conditions on degradation products was fingerprinted by rapid laser desorption ionization-mass spectrometry (LDI-MS) method. ...
Zhang Weichao - - 2014
In this paper, for the hydrogen abstraction reaction of HCHO by OH radicals assisted by water, formic acid or sulfur acid, the possible reaction mechanisms and kinetics have been investigated theoretically using quantum chemistry methods and transition state theory. The potential energy surfaces calculated at the CCSD(T)/6-311++G(df,pd)//MP2(full)/6-311++G(df,pd) levels of theory ...
Tischer Alexander A Division of Hematology, Departments of Internal Medicine, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, - - 2014
The ionic liquid 1-ethyl-3-methyl imidazolium chloride (EMIM Cl) and the amino acid l-ArgHCl have been successfully used to improve the yield of oxidative refolding for various proteins. However, the molecular mechanisms behind the actions of such solvent additives - especially of ionic liquids - are still not well understood. In ...
Stadler Jens M JM Interfaculty Institute of Biochemistry, Auf der Morgenstelle 15. and University of Tübingen, 72076 Tübingen, Germany. - - 2014
Applying psoralen interstrand crosslinks for the photoactivation of nucleic acids is a new concept. To find chromophores that can efficiently stimulate crosslink repair we screened several pyrenes and appended them to peptide nucleic acids for their site-selective addressing. Even though pyrenes conjugated to uracil revealed desirable spectroscopic properties they were ...
Gómez Diego A DA Department of Agricultural Chemistry, Facultad de Ciencias, Universidad Autónoma de Madrid, Carretera Colmenar Viejo km 15, 28049 Madrid, Spain. Electronic address: - - 2014
The effect of NAA (1-naphthaleneacetic acid) on organic acid exudation in white lupin plants grown under phosphorus deficiency was investigated. Plants were sampled periodically for collecting of organic acids (citrate, malate, succinate), and also were used to study the effect on proton extrusion and release of Na(+), K(+), Ca(2+) and ...
Ravasio Davide D Carlsberg Laboratory, Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, - - 2014
Aroma alcohols of fermented food and beverages are derived from fungal amino acids catabolism via the Ehrlich Pathway. This linear pathway consists of three enzymatic reactions to form fusel alcohols. Regulation of some of the enzymes occurs on the transcriptional level via Aro80. The riboflavin overproducer Ashbya gossypii produces strong ...
Prochaska Krystyna K Poznan University of Technology, Institute of Chemical Technology and Engineering, pl. M. Skłodowskiej-Curie 2, 60-965 Poznań, Poland. Electronic address: - - 2014
A novel approach based on a hybrid system allowing nanofiltration, bipolar electrodialysis and reactive extraction, was proposed to remove fumaric acid from fermentation broth left after bioconversion of glycerol. The fumaric salts can be concentrated in the nanofiltration process to a high yield (80-95% depending on pressure), fumaric acid can ...
Umadevi P P Department of Physics, Bharathiar University, Coimbatore 641 046, Tamil Nadu, - - 2014
In this work, using ab initio and density functional theory (DFT) methods halogen substituted formic acid (FA) dimer is studied. The dimer stability is due to the hydrogen bonds, either conventional (OH⋯O, OH⋯F, OH⋯Cl) or non-conventional (CH⋯O, CH⋯F, CH⋯Cl). Among all the dimers, trans-trans form is more stable than the ...
Zhou Alice Qinhua AQ Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT, USA; Integrated Graduate Program in Physical and Engineering Biology (IGPPEB), Yale University, New Haven, CT, USA; Howard Hughes Medical Institute International Research - - 2014
The side-chain dihedral angle distributions of all amino acids have been measured from myriad high-resolution protein crystal structures. However, we do not yet know the dominant interactions that determine these distributions. Here, we explore to what extent the defining features of the side-chain dihedral angle distributions of different amino acids ...
Senol F Sezer - - 2014
Current evidence suggests that endogenous dopamine may act as a neurotoxin following its oxidation to an o-quinone and reaction with cellular thiols, which are neutoxic, which may occur spontaneously or via reaction with tyrosinase or some other enzymes. Tyrosinase (E.C. 1.14.18.1) with two cupper ions coordinated by three histidines is ...
Delattin Nicolas N Centre of Microbial and Plant Genetics, CMPG, KU Leuven, Kasteelpark Arenberg 20, box 2460, 3001 Leuven, - - 2014
We performed a structure-activity relationship study of the antibiofilm plant-derived decapeptide OSIP108. Introduction of positively charged amino acids R, H and K resulted in up to 5-fold increased antibiofilm activity against Candida albicans compared to native OSIP108, whereas substitution of R9 resulted in complete abolishment of its antibiofilm activity. By ...
Tateno Kotaro K Department of Chemistry, Faculty of Science, Tokyo University of Science , 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, - - 2014
Acid-responsive fluorescent compounds were prepared by introducing a nitrophenyl group to L-shaped pentacycles with a pyrrolo[1,2-a][1,8]naphthylidine backbone. These compounds show almost no fluorescence under neutral conditions, but emit green to orange fluorescence upon addition of trifluoroacetic acid. Acid titration experiments and NMR spectroscopy, plus DFT calculations, show that formation of ...
Tzeng Yu-Zan - - 2014
Trans fatty acids (TFAs) create deleterious effects, thus their existence in human is a great health concern. TFAs can be obtained through diet, or they can be formed endogenously by radical induced cis to trans isomerization. The mechanism of isomerization of fatty acid catalyzed by radicals including nitrogen dioxide (NO2(.)), ...
Moon Morgan L ML Division of Nutritional Sciences, University of Illinois, Urbana IL, - - 2014
Excess fat in the diet can impact neuropsychiatric functions by negatively affecting cognition, mood and anxiety. We sought to show that the free fatty acid (FFA), palmitic acid, can cause adverse biobehaviors in mice that last beyond an acute elevation in plasma FFAs. Mice were administered palmitic acid or vehicle ...
Chhetri Ravi Kumar RK Department of Environmental Engineering, Technical University of Denmark, Bygningstorvet, Building 115, 2800 Kgs. Lyngby, - - 2014
We investigated the possibility of applying performic acid (PFA) and peracetic acid (PAA) for disinfection of combined sewer overflow (CSO) in existing CSO management infrastructures. The disinfection power of PFA and PAA towards Escherichia coli (E. coli) and Enterococcus was studied in batch-scale and pre-field experiments. In the batch-scale experiment, ...
Fradinho J C JC REQUIMTE/CQFB, Chemistry Dpt., FCT, Universidade Nova de Lisboa, 2829-516 Caparica, - - 2014
This work studied the effect of the substrate feeding composition on the polyhydroxyalkanoate (PHA) accumulation capacity of an acetate enriched photosynthetic mixed culture (PMC). From the six tested organic acids-malate, citrate, lactate, acetate, propionate and butyrate-only the three volatile fatty acids (VFAs) enabled PHA production, with acetate and butyrate leading ...
Alsufyani Taghreed T Friedrich Schiller University Jena, Institute for Inorganic and Analytical Chemistry, Lessingstr. 8, Jena 07743, - - 2014
Lipoxygenase/hydroperoxide lyase mediated transformations convert polyunsaturated fatty acids into various oxylipins. First, lipoxygenases catalyze fatty acid oxidation to fatty acid hydroperoxides. Subsequently, breakdown reactions result in a wide array of metabolites with multiple physiological and ecological functions. These fatty acid transformations are highly diverse in marine algae and play a ...
Tao Li L Department of Pharmacology, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, - - 2014
Integrated research of herbs and formulas characterized by functions of promoting blood circulation and removing blood stasis is one of the most active fields in traditional Chinese medicine. This paper strives to demonstrate the roles of a homologous series of phenolcarboxylic acids from these medicinal herbs in cancer treatment via ...
Sahu Bidya Dhar BD Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, 500 007, - - 2014
Carnosic acid is a well-known antioxidant. Recently, it has been identified as modulator of nuclear factor erythroid 2-related factor 2 (Nrf2). The effect of carnosic acid in the context of cardiovascular disorders has not been studied. In the present study, we investigated the beneficial effect and the underlying cardioprotective mechanism ...
Diwakar Ganesh G Analytical Sciences, Research & Development, Amway Corporation, 7575 Fulton St East, Ada, MI 49355, USA. Electronic address: - - 2014
In recent years, dietary fatty acids have been extensively evaluated for nutritional as well as cosmetic benefits. Among the dietary fats, the omega-3 (ω3) and omega-6 (ω6) forms of polyunsaturated fatty acids (PUFAs) have been found to exhibit many biological functions in the skin such as prevention of transepidermal water ...
Zhou Shengfei S Department of Biological System Engineering, University of Wisconsin, Agricultural Engineering Building, Madison, WI 53706, USA. Electronic address: - - 2014
This work studied the two-step acid hydrolysis for determining carbohydrates in lignocellulosic biomass. Estimation of sugar loss based on acid hydrolyzed sugar standards or analysis of sugar derivatives was investigated. Four model substrates (starch, holocellulose, filter paper and cotton) and three levels of acid/material ratios (7.8, 10.3 and 15.4, v/w) ...
Pal Priyanka D PD Department of Biophysics, University Of Mumbai, Vidyanagri Santacruz (E), Mumbai, 400098, - - 2014
Biological macromolecules evolve and function within intracellular environments that are crowded with other macromolecules. Crowding results in surprisingly large quantitative effects on both the rates and the equilibria of interactions involving macromolecules, but such interactions are commonly studied outside the cell in uncrowded buffers. The addition of high concentrations of ...
Yoon Jisoo J Department of Chemistry, Research Institute for Basic Sciences, Kyung Hee University, Seoul 130-701, Korea. - - 2014
A chemosensor compound () consisting of a central ferrocene with two butylaminomethyl arms showed unexpected facile electrochemical oxidation of the secondary amines in proximity to the ferrocene, which was utilized for electrochemical discrimination of phthalic acid selectively over two other isomers, isophthalic acid and terephthalic acid.
Ozkul Yilmaz Y From the Department of Otorhinolaryngology, Izmir Katip Celebi University, Ataturk Training and Research Hospital, Izmir, - - 2014
The aim of our study was to determine the effectiveness of intratympanic α-lipoic acid injection as an otoprotective agent against cisplatin-induced ototoxicity in guinea pigs. Twenty-four adult male albino guinea pigs with normal hearing were divided into 4 groups. The guinea pigs received intraperitoneal cisplatin in group 1, intraperitoneal cisplatin ...
Sittiwong Wantanee W Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304 - - 2014
Eleven fatty acid analogues incorporating four-membered carbocycles (cyclobutenes, cyclobutanes, cyclobutanones, and cyclobutanols) were investigated for the ability to inhibit the growth of Mycobacterium smegmatis (Msm) and Mycobacterium tuberculosis (Mtb). A number of the analogues displayed inhibitory activity against both mycobacterial species in minimal media. Several of the molecules displayed potent ...
Torres-Moreno M M Health Sciencies and Welfare Faculty, Department of Health and Social Action, University of Vic - Central University of Catalonia, Vic, Spain. Electronic address: - - 2015
Nutritional composition and fatty acids (FA) profile were determined in cocoa and chocolates of different geographical origin and subject to different processing conditions. Cocoa butter was the major nutrient in cocoa beans and carbohydrates were the most important in chocolates. Cocoa composition and FA profile varied depending on geographical origin ...
Rabinovitz Sharon S School of Criminology, University of Haifa, Israel; Psychopharmacology Laboratory, Bar Ilan University, Israel - - 2014
Cigarette smoke induces oxidative stress with subsequent polyunsaturated fatty acids (PUFAs) peroxidation. Low concentrations of omega-3 PUFAs can affect neurotransmission, resulting in hypofunctioning of the mesocortical systems associated with reward and dependence mechanisms and thus may increase cigarette craving, hampering smoking cessation efforts. PUFA deficiency, in particular eicosapentaenoic acid (EPA; ...
Wang Hong-Lei HL Department of Biology, Lund University, 223 62, Lund, Sweden, - - 2014
Representatives of the highly speciose tropical butterfly genus Bicyclus (Lepidoptera: Nymphalidae) are characterized by morphological differences in the male androconia, a set of scales and hair pencils located on the surface of the wings. These androconia are assumed to be associated with the release of courtship pheromones. In the present ...
Pei Fei F College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR - - 2014
Button mushroom slices were dehydrated using freeze drying (FD) or FD combined with microwave vacuum drying (FMVD), and the non-volatile component profiles were studied. The results showed that the level of non-volatile components in button mushroom firstly increased during sublimation of FD/FMVD process and then fell during desorption in FD ...
Ye Shuhong S School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, - - 2014
The crude exopolysaccharides (EPSs) were obtained from Arthrobacter ps-5 fermentation using various carbohydrate sources followed by centrifugation, ethanol precipitation, and the isolated EPSs were further deproteinized and lyophilized. Carbohydrates from various sources resulted in different yield of EPSs from the fermentation and different molecular weight of EPSs. A maximum yield ...
Karlsson Isabella - - 2014
Photocontact allergy is a well-known side effect of topical preparations of the nonsteroidal anti-inflammatory drug ketoprofen. Photocontact allergy to ketoprofen appears to induce a large number of photocross-allergies to both structurally similar and structurally unrelated compounds. Contact and photocontact allergy is explained by structural modification of skin proteins by the ...
Zhang Hong-Jia HJ College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, - - 2014
Steam explosion is the most promising technology to replace conventional acid hydrolysis of lignocellulose for biomass pretreatment. In this paper, a new screw-steam-explosive extruder was designed and explored for xylose production and lignocellulose biorefinery at the pilot scale. We investigated the effect of different chemicals on xylose yield in the ...
Ma Guobin G School of Materials Science and Engineering, Department of Chemistry, Shanghai University, Shanghai 200444, China. wanwen@staff.shu.edu.cn - - 2014
A copper-mediated gem-difluoromethylenation of aryl, heteroaryl and vinyl boronic acids with bromodifluoromethylated oxazole or thiazole derivatives has been developed. This novel reaction showed an excellent functional group tolerance and wide substrate scope, providing facile access to practical application in drug discovery and development.
Mercali Giovana Domeneghini - - 2014
In this work, the influence of electric field frequency and solids content on the degradation kinetics of ascorbic acid during ohmic heating of acerola pulp and acerola serum was investigated. The degradation percentage of ascorbic acid in the pulp after 120 min of heating varied between 12 and 17%. For ...
Xiao Chaoni C College of Life Sciences, Northwest University, Xi'an, 710069, - - 2014
Weak self-interaction plays an important role in interpreting the biomechanisms and modes of drug action. The structure-dependent self-association of five phenolic acids with various bioactivities, including danshensu (DSS), caffeic acid (CA), rosmarinic acid (RA), lithospermic acid (LA), and salvianolic acid B (SA), was investigated by (1) H NMR. These phenolic ...
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