Search Results
Results 151 - 200 of 2159
1 2 3 4 5 6 7 8 9 10 >
Kromhout Daan - - 2012
Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present ...
Dyall Simon C - - 2011
There is growing interest into researching omega-3 fatty acids; however, there are considerable variations in the methodologies employed. Many studies add oils to animal feed and under ambient conditions omega-3 fatty acids are particularly unstable and prone to autoxidation and peroxidative damage. It is therefore important to take specific precautions ...
Barth M - - 2012
Background: Aromatic amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive disorder resulting in a combined dopamine and serotonin deficiency. About 50% of the cases set in the neonatal period. Here, we report an atypical clinical presentation with moderate symptoms. Patient: At 10months old, the patient presented paroxysmal eye ...
Berdyshev Evgeny V - - 2011
Fatty aldehydes are important components of the cellular lipidome. Significant interest has been developed towards the analysis of the short chain α,β-unsaturated and hydroxylated aldehydes formed as a result of oxidation of polyunsaturated fatty acids. Multiple gas chromatography-mass spectrometry (GC/MS) and subsequently liquid chromatography-mass spectrometry (LC/MS) approaches have been developed ...
Corvis Yohann - - 2011
The aim of this study was to investigate the solid dispersion phase behavior of s- or rs-ibuprofen in stearic acid. By means of thermal analysis, we have demonstrated the total immiscibility, in solid state, of the corresponding binary mixtures. This indicates that no specific interactions exist between the chosen excipient ...
Kantchev Eric Assen B - - 2011
A density functional theory study of the addition of phenylboronic acid to cyclohexenone catalyzed by chiral 1,4-diene-Rh(i) catalyst reveals that 1,4-addition is thermodynamically preferred. The enthalpy-driven enantioselection occurs during the carborhodation step and not the enone binding step, as previously proposed. The chiral ligand selectively destabilizes the disfavored transition state ...
Hill Robert A - - 2011
A personal selection of 31 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as artalbic acid from Artemisia alba.
Macdonald A - - 2011
The same basic principles are used to deliver dietary treatment in PKU that was developed sixty years ago. Dietary treatment is undoubtedly very successful, but it has gradually evolved and been guided commonly by individual experience and expert opinion only. There is little international consensus about dietary practice with improvements ...
McNeil Julian David - - 2011
Intra-articular hyaluronic acid preparations have been available for the treatment of osteoarthritis of the knee for over 15 years. Their use has been limited by cost, difficulties of administration and conflicting evidence of efficacy. Difficulties in conducting adequate clinical trials have resulted in the appearance of multiple meta-analyses whose findings are ...
Khanna Neena - - 2011
Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma, Riehl's melanosis, Lichen planus pigmentosus, erythema dyschromicum perstans (EDP), erythrosis, and poikiloderma of Civatte. But there is considerable overlap in features amongst the ...
Plank Christian - - 2011
Nucleic acids carry the building plans of living systems. As such, they can be exploited to make cells produce a desired protein, or to shut down the expression of endogenous genes or even to repair defective genes. Hence, nucleic acids are unique substances for research and therapy. To exploit their ...
Madden Jacqueline J Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK. - - 2011
The cardioprotective actions of the fish oil (FO)-derived long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been demonstrated, and dose-response relationships have been defined. However, there is a substantial and well-recognized within-population heterogeneity in response to FO, the etiology of which is ...
Serini S - - 2011
As the concepts of pharmaconutrition are receiving increasing attention, it seems essential to clearly assess the effects of specific dietary compounds in specific groups of patients or clinical conditions. We are herein interested in better defining the differential anti-neoplastic effects of the two major n-3 long chain polyunsaturated fatty acids ...
Maranto Christina J - - 2011
  Lethal control, which has been used to reduce local abundances of animals in conflict with humans or with endangered species, may not achieve management goals if animal movement is not considered. In populations with emigration and immigration, lethal control may induce compensatory immigration, if the source of attraction remains ...
Kong Fanbin - - 2011
Previous studies have shown that brown rice generates lower glycemic responses than white rice, a trait that may be beneficial in the dietary management of chronic diseases such as diabetes and hyperlipidemia. The objective of this study was to investigate influence of rice digestion on the physical properties of the ...
Zhou Ying - - 2011
Due to the biological importance of amino acids, the development of optical probes for these molecules has been an active research area in recent years. This tutorial review focuses on recent contributions since the year 2000 concerning the fluorescent or colorimetric sensors for amino acids, and is organized according to ...
Van Oudenhove Lukas - - 2011
Although a relationship between emotional state and feeding behavior is known to exist, the interactions between signaling initiated by stimuli in the gut and exteroceptively generated emotions remain incompletely understood. Here, we investigated the interaction between nutrient-induced gut-brain signaling and sad emotion induced by musical and visual cues at the ...
Cropley Vanessa - - 2011
RATIONALE: Caffeine exerts positive effects on cognitive and behavioral processes, especially in sub-optimal conditions when arousal is low. Apart from caffeine, coffee contains other compounds including the phenolic compounds ferulic acid, caffeic acid, and the chlorogenic acids, which have purported antioxidant properties. The chlorogenic acids are the most abundant family ...
Lumsden Mary Ann - - 2011
Heavy menstrual bleeding (HMB, also known as menorrhagia) is an important health problem that interferes with women's quality of life. It is one of the most common reasons why women are seen by their family doctors in primary care and is a condition frequently treated by surgery. This review covers ...
Sergeant Susan - - 2012
Over the past 50 years, increases in dietary n-6 PUFA, such as linoleic acid, have been hypothesised to cause or exacerbate chronic inflammatory diseases. The present study examines an individual's innate capacity to synthesise n-6 long-chain PUFA (LC-PUFA) with respect to the fatty acid desaturase (FADS) locus in Americans of ...
Rofail D - - 2012
Studies in the 1990s have found that periconceptional dietary folate, supplementation of folic acid or supplemental multivitamins containing folic acid, help prevent neural tube defect (NTDs) if taken at the right time. This literature review assesses the extant folic acid public health campaigns literature and identifies some common variables used ...
Tul'skaya E M - - 2011
The subject of the present review is the structural diversity and abundance of cell wall teichuronic and teichulosonic acids of representatives of the order Actinomycetales. Recently found teichulosonic acids are a new class of natural glycopolymers with ald-2-ulosonic acid residues: Kdn (3-deoxy-D-glycero-D-galacto-non-2-ulosonic acid) or di-N-acyl derivatives of Pse (5,7-diamino-3,5,7,9-tetradeoxy-L-glycero-L-manno-non-2-ulosonic or ...
Barrette-Ng Isabelle H - - 2011
In introductory biochemistry courses, it is often a struggle to teach the basic concepts of acid-base chemistry in a manner that is relevant to biological systems. To help students gain a more intuitive and visual understanding of abstract acid-base concepts, a simple graphical construct called the pH ruler Java applet ...
Bland Jackie - - 2011
Go Folic! is a major new campaign aimed at getting any woman who might become pregnant to take the right amount of folic acid at the right time. In order to prevent neural tube defects (NTDs), and proactively prevent new cases of spina bifida and hydrocephalus, it is essential that ...
Kicklighter Cynthia E - - 2011
Molecules of keystone significance are relatively rare, yet mediate a variety of interactions between organisms. They influence the distribution and abundance of species, the transfer of energy across multiple trophic levels, and thus they play significant roles in structuring ecosystems. Despite their potential importance in facilitating our understanding of ecological ...
Vasta Valentina - - 2011
The aim of this study was to assess whether different grazing management affect animal performance and meat fatty acid composition. Thirty-five lambs were divided into three groups: 12 lambs grazed from 9am to 5pm (8h group); 11 lambs grazed from 9am to 1pm (4hAM group) and 12 lambs grazed from ...
Köhler Jens - - 2011
In this communication we report on the base catalyzed Michael addition of the hydroxy methyl side groups in polyglycidol to diethyl vinyl phosphonate. Hydrolysis of the diethyl phosphonato ethyl side groups with bromotrimethylsilane leads to a new class of polyglycidols with pendant phosphonic acid groups.
Zhao Huaping - - 2011
Natural tetramic acid derivatives have attracted a great deal of interest of chemists because of their structural features and the broad range of biological activities. This paper focuses on five naturally occurring tetramic acid derivatives reported to have phytotoxicity and discusses their common structural characteristics. Copyright © 2011 Society of ...
Durak A T - - 2011
The inactivation mechanism of γ-aminobutyric acid aminotransferase (GABA-AT) in the presence of γ-vinyl-aminobutyric acid, an anti-epilepsy drug, has been studied by means of theoretical calculations. Density functional theory methods have been applied to compare the three experimentally proposed inactivation mechanisms (Silverman et al., J. Biol. Chem., 2004, 279, 363). All ...
Fabris D - - 2011
Alternative approaches complementing the existing technologies for analysis of nucleic acids and their assemblies are necessary to take on the new challenges posed by the postgenomic era. The versatility of MS in biopolymer analysis and its ability to reach beyond sequence information are the basis of ever expanding applications aimed ...
Lendemer James C - - 2011
The divaricatic acid-producing populations of Lepraria in North America north of Mexico are revised using traditional morphological characters, chemistry, ecology, biogeography, and ITS1, 5.8S, and ITS2 sequence data. Three taxa are accepted: L. cryophila, L. hodkinsoniana sp. nov., and L. pacifica sp. nov. Both Lepraria crassissima and L. incana are ...
Wang Zhong - - 2011
Combination therapies have recently been shown to be more effective than monotherapies that may provide synergistic effects in the treatment of stroke, but its selective mechanism still remains unclear. Based on the median-effect method, the combination therapy of jasminoidin and ursodeoxycholic acid had a synergic effect on reducing the infarct ...
Galukande M - - 2011
Reference values may vary significantly among populations and cultures for which dietary intakes may be different. Each laboratory is expected to investigate the transferability of the expected values to its own patient population and if necessary determine its own reference ranges. This study sought to establish Folic acid and Vitamin ...
Rocca-Serra Philippe - - 2011
Nucleic acids are particularly amenable to structural characterization using chemical and enzymatic probes. Each individual structure mapping experiment reveals specific information about the structure and/or dynamics of the nucleic acid. Currently, there is no simple approach for making these data publically available in a standardized format. We therefore developed a ...
Calon F - - 2011
The current rise in the prevalence of Alzheimer's disease (AD) is unfortunately not matched by new treatment options. In the last 10 years, epidemiological, preclinical and clinical data have enlightened the possible preventive action of omega-3 polyunsaturated fatty acids (n-3 PUFA) in AD and other diseases. While the contribution of ...
Tokunaga Yuji - - 2011
This paper describes the acid/base-mediated three-state translational isomerization of two [2]rotaxanes, each containing N-alkylaniline and N,N-dialkylamine centers as binding sites for threaded dibenzo[24]crown-8 units. Under neutral conditions, the dialkylamine unit predominantly recognized the crown ether component through cooperative binding of a proton; when both amino units were protonated under acidic ...
Yi Yunni - - 2011
Neural tube defects (NTDs) are the second most common group of serious birth defects. Although folic acid has been shown to reduce effectively the risk of NTDs and measures have been taken to increase the awareness, knowledge, and consumption of folic acid, the full potential of folic acid to reduce ...
Schattenhofer Martha - - 2011
In flow cytometric analyses of marine prokaryotic picoplankton often two populations with distinct differences in their apparent nucleic acid content are discernable, one with a high and one with a low nucleic acid content (HNA and LNA, respectively). In this study we determined the phylogenetic composition of flow cytometrically sorted ...
Natalini Benedetto - - 2011
In a line of research focused on the design, synthesis and development of new bile acid-based compounds, the physico-chemical profile of the molecules must be thoroughly explored and analyzed. In this scenario, a fast and reliable information on the critical micellar concentration (CMC) of specific compounds through a profitable chromatographic ...
Talaulikar Vikram Sinai - - 2011
Folic acid is one of the B complex vitamins and is now recognized as a major component of the periconceptional care of women in the reproductive age group. Deficiency of folic acid can lead to neural tube defects in the fetus and megaloblastic anemia in the mother. Due to its ...
Chan Aegean - - 2011
The function of the epidermis is to form an effective barrier between the dry, external environment and the interior of the body. The barrier specifically resides in the extracellular lipid membranes of the stratum corneum (SC) and an acidic pH is necessary to maintain its competency against various insults. The ...
Gómez Candela C - - 2011
The modification of dietary patterns has led to a change in fatty acid consumption, with an increase in the consumption of ω-6 fatty acids and a marked reduction in the consumption of ω-3 fatty acids. This in turn has given rise to an imbalance in the ω-6/ω-3 ratio, which is ...
Nascimento Marcus Vinícius Mariano - - 2011
This study was performed to determine the antinociceptive and anti-inflammatory activities of ethanolic extract of Lafoensia pacari A. St.-Hil. (PEtExt) stem bark and its fractions using various animal models such as acetic acid-induced abdominal writhing, formalin-induced pain and croton oil-induced ear edema tests. The PEtExt inhibited the acetic acid-induced abdominal ...
Boutaghane Naima - - 2011
The essential oil of Matricaria pubescens (Asteraceae) collected at Ghardaia (Algerian Septentrional Sahara) was studied by GC and GC-MS. Isochrysanthemic acid ethyl ester (26.5%), spathulenol (19.4%), alpha-cadinol (12.9%) and geranylisovalerate (8.2%), were identified as the major components of the essential oil, which was investigated for its analgesic effect.
Zahov Stefan - - 2011
Cytosolic phospholipase A(2) α (cPLA(2) α) and fatty acid amide hydrolase (FAAH) are enzymes that have emerged as attractive targets for the development of analgesic and anti-inflammatory drugs. We recently reported that 1-[3-(4-octylphenoxy)-2- oxopropyl]indole-5-carboxylic acid (5) is a dual inhibitor of cPLA(2) α and FAAH. Structure-activity relationship studies revealed that ...
Lin Gang - - 2011
Amino acids are building blocks of proteins and key regulators of nutrient metabolism in cells. However, excessive intake of amino acids can be toxic to the body. Therefore, it is important to precisely determine amino acid requirements by organisms. To date, none of the methods is completely satisfactory to generate ...
Hofmann Alan F - - 2011
Herbert Falk died on August 8, 2008, after a long illness. It was his vision that initiated the Bile Acid Meetings and brought to market chenodeoxycholic acid and ursodeoxycholic acid for the dissolution of cholesterol gallstones as well as the successful treatment of cholestatic liver disease. The 1st Bile Acid ...
Dunlap Beth - - 2011
This article presents data on the current best evidence-based clinical practices and controversies surrounding folic acid supplementation/fortification for the prevention of neural tube defects (NTDs) during early pregnancy. Formatted as a series of ten clinical questions, answers and extensive discussion are provided for each point. We assess the history and ...
Ramírez-Silva Ivonne - - 2011
There is growing evidence that quality, rather that quantity of fat is the determinant of cardiovascular risk. The objective of the study is to describe quantitatively the intake and adequacy of fatty acid classes among the Mexican population aged 5-90 years from a probabilistic survey. Dietary intake of individual and ...
Banić M - - 2011
The story of gastric acid secretion began with early ideas on gastric secretion (Spallanzani and de Réaumur, 17th century) and with first descriptions of food digestion (Dupuytren and Bichat, Beaumont, early 18th century), followed by proof that gastric juice contained acid (Prout, early 18th century). The research continued with first ...
1 2 3 4 5 6 7 8 9 10 >