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Chen Hongxia H Institute of Chemical Industry of Forest Products, CAF, National Engineering Lab for Biomass Chemical Utilization, Key and Open Laboratory of Forest Chemical Engineering, SFA, Jiangsu Province, Nanjing 210042, - - 2014
Lacquer wax is an important fatty resource obtained from the mesocarp of the berries of Toxicodendron vernicifluum. In order to expand the applications of lacquer wax, we hydrolyzed it after establishing the best conditions for the acid-catalyzed hydrolysis using a Box-Behnken design. Then we synthesized a quarternary ammonium gemini surfactant ...
Scott Joseph W JW Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, - - 2014
The hyperthermophilic archaeon Pyrococcus furiosus grows by fermenting peptides and carbohydrates to organic acids. In the terminal step, acyl-CoA synthetase (ACS) isoenzymes convert acyl-CoA derivatives to the corresponding acid and conserve energy in the form of ATP. ACS1 and ACS2 were previously purified from P. furiosus and have α 2 ...
Choi Cheol Soon CS 0000-0002-6405-6017 Department of Biomedical Materials Engineering, Kangwon National University, Chuncheon 200-701, Republic of - - 2014
This study investigated the cultivation of the marine microalga Chlorella sp. without supplying an inorganic carbon source, but instead with enriching the media with extracts of oyster shells pretreated by a high-pressure homogenization process. The pretreated oyster shells were extracted by a weak acid, acetic acid, that typically has harmful ...
Das Madhumita M Biochemistry Lab, GNRC Hospitals, Dispur, Guwahati 6, 781006, India ; GNRC Lab Services, GNRC Hospitals, Dispur, Guwahati 781006, - - 2014
This study was designed to establish reference ranges for serum uric acid among healthy adult Assamese population. Samples from 1470 aged 35-86 years were used to establish age and sex related reference range by the centile method (central 95 percentile) for serum uric acid level. There were 51% (n = ...
Uddin Md Kamal MK Institute of Tropical Agriculture, University Putra Malaysia, Serdang, - - 2014
Purslane (Portulaca oleracea L.) is an important plant naturally found as a weed in field crops and lawns. Purslane is widely distributed around the globe and is popular as a potherb in many areas of Europe, Asia, and the Mediterranean region. This plant possesses mucilaginous substances which are of medicinal ...
Gonçalves F A G FA Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, - - 2014
Yarrowia lipolytica is a nonpathogenic dimorphic aerobic yeast that stands out due to its ability to grow in hydrophobic environments. This property allowed this yeast to develop an ability to metabolize triglycerides and fatty acids as carbon sources. This feature enables using this species in the bioremediation of environments contaminated ...
Flaven-Pouchon Justin J Centre des Sciences du Goût et de l'Alimentation, UMR 6265 CNRS, UMR 1324 INRA, Université de Bourgogne, Dijon, - - 2014
Food and host-preference relies on genetic adaptation and sensory experience. In vertebrates, experience with food-related cues during early development can change adult preference. This is also true in holometabolous insects, which undergo a drastic nervous system remodelling during their complete metamorphosis, but remains uncertain in Drosophila melanogaster. We have conditioned ...
Barros Marcelo P MP Institute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, 01506-000 São Paulo, Brazil. - - 2014
The consumption of marine fishes and general seafood has long been recommended by several medical authorities as a long-term nutritional intervention to preserve mental health, hinder neurodegenerative processes, and sustain cognitive capacities in humans. Most of the neurological benefits provided by frequent seafood consumption comes from adequate uptake of omega-3 ...
Carta Gianfranca G Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, S.S. 554, km. 4500, Monserrato, Cagliari 09042, Italy. - - 2014
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner. Dietary conjugated linoleic acid (CLA) is a fatty acid with a conjugated diene structure that is found in low concentrations in ruminant ...
Ramezani Fatemeh F Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, - - 2013
The study of nanomaterial/biomolecule interface is an important emerging field in bionanoscience, and additionally in many biological processes such as hard-tissue growth and cell-surface adhesion. To have a deeper understanding of the amino acids/gold nanoparticle assemblies, the adsorption of these amino acids on the gold nanoparticles (GNPs) has been investigated ...
Condon David E - - 2013
Locked Nucleic Acids (LNAs) are RNA analogues with an O2'-C4' methylene bridge which locks the sugar into a C3'-endo conformation. This enhances hybridization to DNA and RNA, making LNAs useful in microarrays and potential therapeutics. Here, the LNA, L(CAAU), provides a simplified benchmark for testing the ability of molecular dynamics ...
Burel Laurence L IRCELYON - UMR 5256 CNRS-Université de Lyon 1, 2, Av. A. Einstein 69626 Villeurbanne Cedex - - 2013
Ge-containing ITQ-22 zeolites have been almost completely degermanated under strong acidic conditions without modifications of the framework topology. Simultaneous to Ge extraction, the framework was partially dissolved; mesopores were formed but the structure was maintained through the re-incorporation of some of silicon species at vacant sites. The presence of many ...
Sjöblom Johan J Ugelstad Laboratory, Norwegian University of Science and Technology, 7491 Trondheim, - - 2013
This article reviews the properties of a novel class of molecules: the tetrameric acids. These molecules have brought a large interest in petroleum science since the discovery of the family of molecules named ARN in 2004. ARN, which is naturally present in oil, is responsible, by reaction with calcium ion, ...
Payne Gareth G Reading Scientific Services Ltd, Reading Science Centre, Whiteknights Campus, Pepper Lane, Reading RG6 6LA, - - 2013
Neutral-lipids within oilseeds are most commonly stored in oil bodies, small spherical organelles with oleosin proteins inserted through a phospholipid monolayer. Oil bodies extracted from Echium plantagineum are highly enriched in polyunsaturated fatty acids and are stable to coalescence and oxidation. This stability has been attributed to the strong association ...
Beales Paul A PA School of Chemistry, University of Leeds, Leeds LS2 9JT, UK. Electronic address: - - 2013
We present a critical review of recent work related to the assembly of multicompartment liposome clusters using nucleic acids as a specific recognition unit to link liposomal modules. The asymmetry in nucleic acid binding to its non-self complementary strand allows the controlled association of different compartmental modules into composite systems. ...
Ho Van Thi Thuy VT Food Science and Technology, School of Chemical Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia. Electronic address: - - 2013
Cocoa beans (Theobroma cacao) are the major raw material for chocolate production and fermentation of the beans is essential for the development of chocolate flavor precursors. In this study, a novel approach was used to determine the role of yeasts in cocoa fermentation and their contribution to chocolate quality. Cocoa ...
Torres Manuel M Laboratory of Molecular Cell Biomedicine, University of the Balearic Islands, Palma de Mallorca, Spain. Electronic address: - - 2013
Alzheimer's disease (AD) is a neurodegenerative pathology with relevant unmet therapeutic needs. Both natural aging and AD have been associated with a significant decline in the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA), and accordingly, administration of DHA has been proposed as a possible treatment for this pathology. However, recent ...
Vaquero Isabel I Algal Biotechnology Group, International Centre for Environmental Research (CIECEM), Parque Dunar s/n, Matalascañas, Almonte, 21760, Huelva, - - 2013
This study was aimed at increasing productivity of a novel lutein-rich acidic environment microalga, C. onubensis, based on efficient inorganic carbon use. Productivity was determined based on dry weight data, inorganic carbon concentration mechanisms were determined by means of carbonic anhydrase activity; carotenoids were extracted with methanol and measured by ...
Unterecker Stefan S Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, - - 2013
Valproic acid and the antidepressants doxepin and venlafaxine are frequently used psychotropic drugs. In the literature, an influence of valproic acid on serum levels of antidepressants has been described, although studies have focused on amitriptyline. The authors assessed their therapeutic drug monitoring (TDM) database for patients receiving a combination of ...
Lee Hwanhwi H Division of Environmental Science & Ecological Engineering, Korea University, Republic of - - 2013
White rot fungi are essential in forest ecology and are deeply involved in wood decomposition and the biodegradation of various xenobiotics. The fungal ligninolytic enzymes involved in these processes have recently become the focus of much attention for their possible biotechnological applications. Successful bioremediation requires the selection of species with ...
Angelovici Ruthie R Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan - - 2013
Branched-chain amino acids (BCAAs) are three of the nine essential amino acids in human and animal diets and are important for numerous processes in development and growth. However, seed BCAA levels in major crops are insufficient to meet dietary requirements, making genetic improvement for increased and balanced seed BCAAs an ...
Rodgers Kenneth J KJ School of Medical and Molecular Biosciences (04.06.35A), University of Technology, Harris Street, Sydney, NSW 2007, Australia. Electronic address: - - 2013
Animals, in common with plants and microorganisms, synthesise proteins from a pool of 20 protein amino acids (plus selenocysteine and pyrolysine) (Hendrickson et al., 2004). This represents a small proportion (~2%) of the total number of amino acids known to exist in nature (Bell, 2003). Many 'non-protein' amino acids are ...
George Michael - - 2013
Objective: ACR and EULAR guidelines recommend colchicine to prevent gout flares in patients initiating and increasing uric acid lowering therapy until serum uric acid is maintained at ≤ 6 mg/dL. We aimed to evaluate how well colchicine prescribing practices adhere to these guidelines and examine factors associated with improved prescribing. ...
Espaillat Akbar A Centro de Biología Molecular `Severo Ochoa', Universidad Autónoma de Madrid-Consejo Superior de Investigaciones Científicas (CSIC), 28049 Madrid, - - 2014
Broad-spectrum amino-acid racemases (Bsrs) enable bacteria to generate noncanonical D-amino acids, the roles of which in microbial physiology, including the modulation of cell-wall structure and the dissolution of biofilms, are just beginning to be appreciated. Here, extensive crystallographic, mutational, biochemical and bioinformatic studies were used to define the molecular features ...
Jiang Yuelu Y Department of Marine Biology, Texas A&M University at Galveston, Galveston, 77553 TX, USA. Electronic address: - - 2013
Nitzschia sp. (Bacillariophyceae) was grown under temperature and photoperiods mimicking those, typical during summer, spring/fall and winter conditions in the southern United States, and using five silicate (Si) concentrations. In general, higher Si concentrations resulted in higher growth rates in summer and spring/fall conditions and lower organic content. Si-deficient Nitzschia ...
Lee Chang Ho CH Chang Ho Lee, Ji Hyun Kim, Seong-Wook Lee, Department of Molecular Biology, Institute of Nanosensor and Biotechnology, Dankook University, Yongin 448-701, South - - 2013
In this review, we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus (HCV) infection. Because the HCV genome is present exclusively in RNA form during replication, various nucleic acid-based therapeutic approaches targeting the HCV genome, such as ribozymes, aptamers, siRNAs, and antisense oligonucleotides, have been ...
Hossain Gazi Sakir GS Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, - - 2013
L-Amino acid oxidases (LAAOs), which catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia, are flavin adenine dinucleotide-containing homodimeric proteins. L-Amino acid oxidases are widely distributed in diverse organisms and have a range of properties. Because expressing LAAOs as recombinant proteins in heterologous hosts is difficult, ...
Szostak Michal M School of Chemistry, University of Manchester , Oxford Road, Manchester, M13 9PL, - - 2013
Lewis acid promoted cleavage of α-amino alcohols derived from barbituric acids via chemoselective Sm(II)-mediated electron transfer affords a wide range of C6-substituted 5,6-dihydrouracils. The reaction involves the first generation of N-acyliminium ions directly from the versatile barbituric acids and proceeds with excellent stereoselectivity. The products are shown to be active ...
Rodríguez Francisco J FJ Department of Chemistry, Higher Polytechnic School, University of Burgos, Av. Cantabria s/n, 09006 Burgos, Spain. Electronic address: - - 2013
The main objective of this work (Part II) is to evaluate the usefulness of fluorescence techniques to monitor structural changes in humic substances produced by the ozonation treatment, using all the current fluorescence techniques: Emission scan fluorescence (ESF), synchronous fluorescence spectroscopy (SFS), total luminescence spectroscopy (TLS or EEM) through the ...
Rodríguez Francisco J FJ Department of Chemistry, Higher Polytechnic School, University of Burgos, Av. Cantabria s/n, 09006 Burgos, Spain. Electronic address: - - 2013
The main objective of this work (Part I) is to conduct a comprehensive structural characterization of humic substances, using all the current fluorescence techniques: emission scan fluorescence (ESF), synchronous fluorescence spectroscopy (SFS), total luminescence spectroscopy (TLS or EEM) through the use of both 2-D contour maps and 3-D plots, fluorescence ...
Khan Nazmul Abedin NA Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University, Daegu 702-701 (Korea), Fax: - - 2014
Acidic ionic-liquids (IL) supported on metal-organic frameworks (MOFs) have been shown to be beneficial for adsorptive desulfurization. A remarkable improvement in the adsorption capacity (ca. 71%) was observed in for ILs supported on MIL-101 compared with virgin MIL-101. The improved adsorptive performance might be explained by the acid-base interactions between ...
Li Hong-Shuang - - 2013
An efficient construction of 2-sulfonylbenzo[b]furans is achieved from readily available trans-2-hydroxycinnamic acids and sodium sulfinates mediated by CuCl2•2H2O/AgTFA system under mild conditions. This unprecedented synthetic protocol provides an expedient access to a series of products in one step via a cascade reaction of protodecarboxylation/C-S/C-O bond formation.
Vázquez-Calvo Angela A Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Cantoblanco, Madrid - - 2013
The foot-and-mouth disease virus (FMDV) capsid is highly acid-labile, but introduction of amino acid replacements including an N17D change in VP1 can increase its acid resistance. Using VP1N17D mutant as a starting point, we isolated a virus with higher acid resistance carrying an additional replacement, VP2H145Y, in a residue highly ...
Liu Hui H CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China. Electronic address: - - 2013
With the depletion of the nonrenewable petrochemical resources and the increasing concerns of environmental pollution globally, biofuels and biobased chemicals produced from the renewable resources appear to be of great strategic significance. The present review described the progress in the biosynthesis of fatty acid and its derivatives from renewable biomass ...
Groenewald Wilma W Department of Biochemistry, University of Pretoria, Pretoria 0002, South Africa; School of Chemistry, University of Wales Bangor, Bangor, LL57 2UW, - - 2013
Mycolic acids are structural components of the mycobacterial cell wall that have been implicated in the pathogenicity and drug resistance of certain mycobacterial species. They also offer potential in areas such as rapid serodiagnosis of human and animal tuberculosis. It is increasingly recognised that conformational behaviour of mycolic acids is ...
Lou Jerry J JJ Department of Pathology and Laboratory Medicine (Neuropathology), David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: - - 2013
Frozen biospecimens are crucial for translational research and contain well preserved nucleic acids and protein. However, the risk for catastrophic freezer failure as well as space, cost, and environmental concerns argue for evaluating long-term room temperature storage alternatives. Formalin-fixed paraffin embedded (FFPE) tissues have great value but their use is ...
Gao Xiadi X Department of Chemical and Environmental Engineering, Bourns College of Engineering, University of California, Riverside, 1084 Columbia Avenue, Riverside, CA, 92507; Center for Environmental Research and Technology, Bourns College of Engineering, University of California, Riverside, 1084 Columbia Avenue, Riverside, CA, 92507; BioEnergy Science Center (BESC), Oak Ridge National Laboratory, Oak Ridge, TN, - - 2013
As the second most common polysaccharides in nature, hemicellulose has received much attention in recent years for its importance in biomass conversion in terms of producing high yields of fermentable sugars and value-added products, as well as its role in reducing biomass recalcitrance. Therefore, a time and labor efficient method ...
Hadi Alkarawi H H Functional Ecology Group, Institute of Biology and Environmental Sciences, University of Oldenburg, Oldenburg, Germany; Foundation of Technical Education, Al-Musaib Technical College, Babylon, - - 2013
Phytic acid or phytate, the free-acid form of myo-inositolhexakiphosphate, is abundant in many seeds and fruits, where it represents the major storage form of phosphorus. Although also known from other plant tissues, available reports on the occurrence of phytic acid, e.g. in leaves, have never been compiled, nor have they ...
Bigini Paolo P Department of Biochemistry and Molecular Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri" , Via La Masa 19, 20156 Milan, - - 2013
This study describes the formulation optimization and body-cell distribution and clearance in mice of a dually fluorescent biodegradable poly avidin nanoassembly based on the novel Avidin-Nucleic-Acid-Nano-ASsembly (ANANAS) platform as a potential advancement of classic avidin/biotin-based targeted delivery. The nanoformulation circulates freely in the bloodstream; it is slowly captured by filter ...
Wu Chongde C College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu, 610065, China, - - 2013
Lactic acid bacteria (LAB) are widely used for the production of a variety of fermented foods, and are considered as probiotic due to their health-promoting effect. However, LAB encounter various environmental stresses both in industrial fermentation and application, among which acid stress is one of the most important survival challenges. ...
Silva Veronica V 1Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah Tikva, - - 2013
A biomarker is a measured characteristic that may be used as an indicator of some biological state or condition. In health and disease, biomarkers have been used not only for clinical diagnosis purposes but also as tools to assess effectiveness of a nutrition or drug intervention. When considering nutrition studies, ...
Zhang Guodong G Department of Entomology and Comprehensive Cancer Center, University of California, Davis, CA, 95616; Department of Food Science, University of Massachusetts, Amherst, MA, - - 2013
Epoxygenated fatty acids (EpFAs), which are lipid mediators produced by cytochrome P450 epoxygenases from polyunsaturated fatty acids, are important signaling molecules known to regulate various biological processes including inflammation, pain and angiogenesis. The EpFAs are further metabolized by soluble epoxide hydrolase (sEH) to form fatty acid diols which are usually ...
Kim Gi-Ppeum GP Department of Herbal Medicine Resource, Dogye Campus, Kangwon National University, Hwangjori #3, Dogye-up, Samcheok 245-907, Republic of - - 2014
This study was aimed to determine the contents and the association of B vitamins from seeds of 10 black and one yellow soybean (Glycine max (L.) Merr.) varieties with either green or yellow cotyledon. Thiamine, flavin adenine dinucleotide (FAD), riboflavin and total riboflavin were found highest in 'Chengjakong', while flavin ...
Toci Aline T AT Núcleo de Pesquisa em Café Prof. Luiz Carlos Trugo, Laboratório de Química e Bioatividade de Alimentos, Instituto de Nutrição, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Programa de Pós-Graduação em Ciência de Alimentos, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, - - 2014
In the present work, the volatile profiles of green and roasted Brazilian defective coffee seeds and their controls were characterised, totalling 159 compounds. Overall, defective seeds showed higher number and concentration of volatile compounds compared to those of control seeds, especially pyrazines, pyrroles and phenols. Corroborating our previous results, butyrolactone ...
Gamboa-Santos Juliana J Instituto de Investigación en Ciencias de la Alimentación (CIAL) (CSIC-UAM) CEI (CSIC+UAM), Nicolás Cabrera 9, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, - - 2014
In this paper, a study on the usefulness of the determination of vitamin C together with indicators of the initial steps of Maillard reaction (2-furoylmethyl amino acids, 2-FM-AA) during the convective drying of strawberries has been carried out for the first time, paying special attention to the kinetics of degradation ...
Rudnick Gary G Department of Pharmacology, Yale University School of Medicine, New Haven, CT, - - 2013
The human SLC6 family is composed of approximately 20 structurally related symporters (co-transporters) that use the transmembrane electrochemical gradient to actively import their substrates into cells. Approximately half of the substrates of these transporters are amino acids, with others transporting biogenic amines and/or closely related compounds, such as nutrients and ...
Sakurai Kenta K Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo 153-8902, - - 2013
Chlamydomonas reinhardtii is a model alga for studying triacylglycerol (TAG) accumulation in the photosynthetic production of "biofuel". Previous studies were conducted under photoheterotrophic growth conditions supplemented with acetate and/or ammonium. We wanted to demonstrate TAG accumulation under truly photoautotrophic conditions without reduced elements. First, we reidentified all lipid components and ...
Caragata Eric P EP School of Biological Sciences, Monash University, Melbourne, VIC, Australia, - - 2013
The endosymbiont Wolbachia represents a promising method of dengue control, as it reduces the ability of the primary vector, the mosquito Aedes aegypti, to transmit viruses. When mosquitoes infected with the virulent Wolbachia strain wMelPop are fed non-human blood, there is a drastic reduction in mosquito fecundity and egg viability. ...
Chen Weijie W Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United - - 2013
The direct α-arylation/N-alkylation of cyclic amines was achieved in a redox-neutral fashion under mild conditions. Transformations occur in the absence of any additives or are promoted by simple carboxylic acids.
Lin Peter T PT Mayo Clinic, Hilton 11, 200 First St SW, Rochester, MN - - 2013
Suicide by inhalation of carbon monoxide produced by mixing formic acid and sulfuric acid within a confined space is a rare method of suicide. This method is similar to the so-called "detergent suicide" method where an acid-based detergent is mixed with a sulfur source to produce hydrogen sulfide. Both methods ...
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