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Esmaeli Shahnaz S Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, - - 2014
Differentiation of mesenchymal stem cells (MSCs) to hepatocyte-like cells is associated with morphological and biological changes. In this study, the effect of hepatogenic differentiation on fatty acid profile and the expression of proliferator-activated receptors-α (PPAR-α) have been studied. For this purpose, MSCs isolated from human umbilical cord were differentiated into ...
Hahm Jong Ryeal JR Department of Internal Medicine, Gyeongsang National University School of Medicine. JinJu, Republic of Korea 660-290; Institute of Health Sciences, Gyeongsang National University School of Medicine. JinJu, Republic of Korea - - 2014
During the adipocyte differentiation, some intracellular organelles are degraded and instead lipid droplets are gradually accumulated in the cytoplasm for energy storage. Autophagy, a self-eating process, has been implicated in the removal of intracellular components in adipogenesis, but its mechanism is poorly understood. In this work we examined how α-lipoic ...
Shang Zhouchun - - 2014
In addition to providing energy and constituting cell membrane, fatty acids also play an important role in adipocyte differentiation and lipid metabolism. As an important member of monounsaturated fatty acids, oleate, together with other components, is widely used to induce chicken preadipocyte differentiation. However, it is not clear whether oleate ...
Hu Xiangang X Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education), College of Environmental Science and Engineering, Nankai University, Tianjin 300071, - - 2014
It is well known that graphene (G) induces nanotoxicity towards living organisms. Here, a novel and biocompatible hydrated graphene ribbon (HGR) unexpectedly promoted aged (two years) seed germination. HGR formed at the normal temperature and pressure (120 days hydration), presented 17.1% oxygen, 0.9% nitrogen groups, disorder-layer structure, with 0.38 nm thickness ...
Casado-Díaz Antonio A Instituto Maimonides de Investigación Biomedica (IMIBIC). Hospital Universitario Reina Sofía de Córdoba, Universidad de Córdoba, 14004, Córdoba, - - 2014
Metabolites derived from the polyunsaturated fatty acids (PUFA) may modulate the mesenchymal stromal cell (MSC) differentiation. Such cells can differentiate into different cellular types, including adipocytes and osteoblasts. Aging favors the bone marrow MSC differentiation toward the former, causing a loss of bone density associated with pathologies like osteoporosis. The ...
Murali Ganesan G Departments of Internal Medicine, Division of Diabetes, Endocrinology, and Metabolism, Omaha, NE, United States; Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, United States; Research Services, VA Nebraska Western Iowa Health Care System, Omaha, NE, United - - 2013
The objective of this study was to determine the effects of enrichment with n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on the differentiation of 3T3-L1 preadipocytes. Enrichment with DHA but not EPA significantly increased the differentiation markers compared to control differentiated cells. DHA compared to EPA treatment ...
Hadzir Siti Norhaiza - - 2013
Suspension mononuclear cells (MNCs) can be differentiated into osteoblasts with the induction of ascorbic acid and β-glycerophosphate. The aim of this study was to determine the ability of suspension MNCs to differentiate into osteoblasts using ascorbic acid only. Suspension MNCs were obtained by a combination of gradient centrifugation and culture ...
Mitome Hidemichi - - 2013
A breath test using [1-(13) C]glycocholic acid as a substrate is a potential diagnostic method for small intestinal bacterial overgrowth syndrome. [1-(13) C]Glycocholic acid has been thus synthesized in an excellent yield from ethyl [1-(13) C]glycinate hydrochloride in a one-pot reaction. This method is suitable for the preparation of the ...
Arisawa Kotoko - - 2013
Lipid droplets (LDs) are independent organelles in adipocytes that are composed of a lipid ester core surrounded by a phospholipid monolayer. The fatty acid composition of the phospholipid monolayer should determine the metabolism and dynamics of LDs. In this study, we examined the fatty acid composition of phospholipid monolayer in ...
Hogarth Cathryn A CA School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, WA 99164, - - 2013
Description of new evidence to support the model for how retinoic acid regulates spermatogonial differentiation, male meiosis and the cycle of the seminiferous epithelium. It has been known since the 1920s that vitamin A is essential for spermatogenesis. However, only recently has significant progress been made toward understanding how the ...
Lewis John - - 2013
Pethidine (meperidine), a synthetic opiate, formally used as an analgesic in surgery and obstetrics, has been an abused drug of choice for some doctors. A case is presented in which a doctor, who previously admitted to using pethidine, was suspected of re-using, following a second positive urine test. A laboratory ...
Kim Hyun-Sung - - 2013
Oleanolic acid, a naturally occurring triterpenoid widely distributed in foods and medicinal plants, has anticancer, antioxidant, and antiaging properties. We hypothesized that oleanolic acid would suppress the production of the inflammatory adipokine resistin during adipogenic differentiation of 3T3-L1 adipocytes. 3T3-L1 adipocytes were cultured in adipogenic media with and without 1 ...
Luo Suhui - - 2013
The present study investigated the roles of folic acid and DNA methyltransferases (DNMTs) in the differentiation of neural stem cells (NSCs). Neonatal rat NSCs were grown in suspended neurosphere cultures and identified by their expression of SOX2 protein and capacity for self-renewal. Then NSCs were assigned to five treatment groups ...
Ida Chieri - - 2013
Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward ...
Komínková Dana - - 2012
Larvae of the three important Central American malaria vectors, Anopheles albimanus, An. vestitipennis, and An. darlingi, are found in distinctly different habitats broadly defined by hydrology and aquatic vegetation, but little is known about the actual food quality and quantity of these habitats. Polyunsaturated fatty acids (PUFA) are of special ...
Casado-Díaz A - - 2012
Arachidonic fatty acid (AA) induces adipogenesis in human mesenchymal stem cells cultures, and high concentrations inhibit osteoblastogenesis; whereas eicosapentaenoic and docosahexaenoic fatty acids do not induce adipogenesis and do not inhibit osteoblastogenesis. In mesenchymal stem cells, omega-6 arachidonic polyunsaturated fatty acid promotes the differentiation of adipocytes and inhibits the osteoblast ...
Taniyasu Sachi - - 2012
A field study on the photolysis of perfluoroalkyl substances (PFASs) was conducted at high altitudes in Mt. Mauna Kea (Hawaii, USA; 4200m) and Mt. Tateyama (Toyama, Japan; 2500m). Results of photolysis of PFASs in the field were further confirmed in laboratory studies. Perfluorooctanesulfonate (PFOS), which is perceived as a non-degradable ...
Cha Dong H - - 2012
Previous studies suggest that olfactory cues from damaged and fermented fruits play important roles in resource recognition of polyphagous spotted wing Drosophila flies (SWD), Drosophila suzukii (Matsumura) (Diptera: Drosophilidae). They are attracted to fermented sweet materials, such as decomposing fruits but also wines and vinegars, and to ubiquitous fermentation volatiles, ...
Davis Michael D - - 2012
Airway pH is central to the physiologic function and cellular biology of the airway. The causes of airway acidification include (1) hypopharyngeal gastric acid reflux with or without aspiration through the vocal cords, (2) inhalation of acid fog or gas (such as chlorine), and (3) intrinsic airway acidification caused by ...
Chia Hui-Ling - - 2012
We present a case of a 10-month-old male infant with thoracoabdominal ectopia cordis, as part of Cantrell pentad, repaired using a poly-L-lactic-polyglycolic acid plate, a resorbable plating system widely used in craniomaxillofacial reconstruction. This is the first reported case of sternal reconstruction using a poly-L-lactic-polyglycolic acid plate. The repair was ...
Venkatramaiah N - - 2012
A novel fluoranthene based fluorescent chemosensor for the detection of picric acid (PA) at the parts per billion (ppb) level was evaluated. Static fluorescence quenching was the dominant process by intercalative π-π interaction between fluoranthene () and nitroaromatics.
Kennedy Allyson E - - 2012
The upper lip and primary palate form an essential separation between the brain, nasal structures and the oral cavity. Surprisingly little is known about the development of these structures, despite the fact that abnormalities can result in various forms of orofacial clefts. We have uncovered that retinoic acid is a ...
Marcheschi Ryan J - - 2012
Nature uses four methods of carbon chain elongation for the production of 2-ketoacids, fatty acids, polyketides, and isoprenoids. Using a combination of quantum mechanical (QM) modeling, protein-substrate modeling, and protein and metabolic engineering, we have engineered the enzymes involved in leucine biosynthesis for use as a synthetic "+1" recursive metabolic ...
Reddy Leleti Rajender - - 2012
A highly enantioselective chiral Brønsted acid catalyzed propargylation of aldehydes with allenylboronate is described. The reaction is shown to be practical and quite general with a broad substrate scope covering aryl, polyaryl, heteroaryl, α,β-unsaturated, and aliphatic aldehydes.
Sabir Ali - - 2012
BACKGROUND: Fatty acids and tocopherols in appropriate quantities are invaluable attributes that are desirable in seeds of agricultural products. Studies have generally focused on the evaluation of the oil and tocopherol components of oil crops. Recently, investigations revealed that the grape seed has robust potential in the production of healthy ...
Breuer Dietmar - - 2012
Until 2009, the limit values for airborne sulfuric acid in Europe were based on the inhalable particle fraction (e.g. MAK (Maximum allowed concentration at workplace) value 0.1 mg m(-3) as the inhalable fraction). With the publication of the Commission Directive 2009/161/EU, an Indicative Occupational Exposure Limit Value (IOELV) of 0.05 ...
Wang Ning - - 2012
The polyfluorinated carboxylic acids 5:3 acid (C(5)F(11)CH(2)CH(2)CO(2)H) and 7:3 acid (C(7)F(15)CH(2)CH(2)CO(2)H) are major products from 6:2 FTOH (C(6)F(13)CH(2)CH(2)OH) and 8:2 FTOH (C(8)F(17)CH(2)CH(2)OH) aerobic biotransformation, respectively. The 5:3 and 7:3 acids were dosed into domestic WWTP activated sludge for 90d to determine their biodegradability. The 7:3 acid aerobic biodegradability was low, ...
Kwaansa-Ansah E E - - 2012
In this study, pH, total organic carbon, sulphate concentration and mercury concentrations of sediment samples from the Volta Lake at Yeji in the northern part of Ghana were determined. The results indicate that pH ranged from 6.32 to 8.21, total organic carbon ranged from 0.17 to 3.02 g/kg and sulphate concentration ...
Lee Chang Kim Jye - - 2012
Heterotrophic growth of thraustochytrids has potential in co-producing a feedstock for biodiesel and long-chain (LC, ≥C(20)) omega-3 oils. Biodiscovery of thraustochytrids from Tasmania (temperate) and Queensland (tropical), Australia, covered a biogeographic range of habitats including fresh, brackish, and marine waters. A total of 36 thraustochytrid strains were isolated and separated ...
Cai Zhiqiang - - 2012
ZJ0273, propyl 4-(2-(4,6-dimethoxypyrimidin-2-yloxy) benzylamino) benzoate, is a novel and broad-spectrum herbicide. In this study, 15 bacteria capable of utilizing ZJ0273 as the sole carbon source were isolated from soil. One of the isolates belonged to the family Amycolatopsis and was designated to Amycolatopsis sp. M3-1; at 30°C and pH 7.0, ...
Huang Jing - - 2012
Molecular dynamics of metabolites is structure dependent and vitally important for their interactive functions in their potential applications as natural materials. To understand the relationship between molecular structure and dynamics, molecular motions of four structurally related ω-amino acids (β-alanine, γ-aminobutyric acid, 5-aminovaleric acid and 6-aminocaproic acid) were investigated by measuring ...
Fromentin Claire - - 2012
The aim of this study was to produce intrinsically and uniformly doubly (15)N-(13)C-labeled proteins. These proteins can be used as intrinsic tracers of dietary amino acids, both α-amino groups and carbon skeletons, during postprandial metabolic utilization. Two (Rhodes) laying hens were fed for 16 days with a standard poultry diet supplemented ...
Noutsopoulos Constantinos - - 2012
The objective of this study was to evaluate the ability of M. parvicella for long chain fatty acids uptake under anaerobic, anoxic and aerobic conditions as well as its ability to utilise volatile fatty acids and long chain fatty acids under anoxic and aerobic conditions. According to the results a ...
Maity Suman - - 2012
The benthic amphipod Diporeia spp. was once the predominant macroinvertebrate in deep, offshore regions of the Laurentian Great Lakes. However, since the early 1990s, Diporeia populations have steadily declined across the area. It has been hypothesized that this decline is due to starvation from increasing competition for food with invasive ...
Iglesias-Sigüenza Javier - - 2012
Lewis adducts between N-heterocyclic carbenes and fullerenes have been isolated and their structures confirmed by X-ray crystallography. This work shows that simple fullerenes such as C(60) or C(70) can act as Lewis acids. This result not only opens new perspectives in fullerene chemistry but might also have strong implications in ...
Kuhns Emily H - - 2012
Fatty acid amino acid conjugates (FACs) in the oral secretions of Lepidopteran larvae are responsible for eliciting plant defense responses. FACs are present despite fitness costs which suggests that they are important for larval survival. In previous work, an aminoacylase (L-ACY-1) was identified as the enzyme responsible for hydrolysis of ...
Reddy Sandeep K - - 2012
Gas phase quantum chemical calculations of linear, hydrogen bonded oligomers of carbonic acid have been carried out to examine the feasibility of such species to be the building blocks of crystalline carbonic acid. Infrared and Raman vibrational spectra have been calculated and are compared against experimentally known spectra for two ...
Halter David - - 2012
Euglena mutabilis is a photosynthetic protist found in acidic aquatic environments such as peat bogs, volcanic lakes and acid mine drainages (AMDs). Through its photosynthetic metabolism, this protist is supposed to have an important role in primary production in such oligotrophic ecosystems. Nevertheless, the exact contribution of E. mutabilis in ...
Ozcan Tamer - - 2012
Accumulation profiles of fatty acids and α-tocopherol were analysed at three ripening stages in the seed oils of Primula and Echium species. Total seed oils were increased considerably with maturation, while α-tocopherol contents decreased in both species. Increased levels of ALA and oleic acid, and decrease in linoleic and palmitic ...
Larsen Molly C - - 2012
Recent experimental and theoretical results have suggested that organic acids such as pyruvic acid, can be photolyzed in the ground electronic state by the excitation of the OH stretch vibrational overtone. These overtones absorb in the near infrared and visible region of the spectrum where the solar photons are plentiful ...
Kraas Femke I - - 2012
The non-ribosomally synthesized lipodepsipeptide CDA belongs to the group of acidic lipopeptide antibiotics, whose members feature a fatty acid side chain that strongly affects their antimicrobial activity. This study elucidates the N-acylation of the N-terminal serine in the CDA peptide chain. This reaction is referred to as lipoinitiation and is ...
Wei Feifei - - 2012
In this paper, we report a <sup>1</sup>H and <sup>13</sup>C NMR-based comprehensive analysis of coffee bean extracts of different degrees of roast. The roasting process of coffee bean extracts was chemically characterized using detailed signal assignment information coupled with multivariate data analysis. Thirty NMR-visible components of coffee bean extracts were monitored ...
He Feng - - 2012
Mechanisms by which dissolved organic matter (DOM) mediates the photochemical reduction of Hg(II) in aquatic ecosystems are not fully understood, owing to the heterogeneous nature and complex structural properties of DOM. In this work, naturally occurring aromatic compounds including salicylic, 4-hydrobenzoic, anthranilic, 4-aminobenzoic, and phthalic acid were systematically studied as ...
Higa Kelly C - - 2012
Nitrogen-fixing heterocysts are arranged in a periodic pattern on filaments of the cyanobacterium Anabaena sp. strain PCC 7120 under conditions of limiting combined nitrogen. Patterning requires two inhibitors of heterocyst differentiation, PatS and HetN, which work at different stages of differentiation by laterally suppressing levels of an activator of differentiation, ...
Inada Makoto - - 2012
Abstract Objective. A traditional measurement of gastric acid, involving nasogastric intubation of stomach and acid suction, has been suggested as a gold standard. However, this causes the patient discomfort and cost increase, and is 'time-consuming'. Material and methods. A calcium [(13)C]carbonate (Ca(13)CO(3)) breath test was carried out in rats without ...
Bu Quan - - 2012
Catalytic microwave pyrolysis of biomass using activated carbon (AC) was investigated to determine the effects of pyrolytic conditions on the yields of phenol and phenolics. Bio-oils with high concentrations of phenol (38.9%) and phenolics (66.9%) were obtained. These levels were higher than those obtained by pyrolysis without AC addition and ...
Wu Li Fen - - 2012
This study investigated nitrogen and phosphorus assimilation and lipid production of microalgae in industrial wastewater. Two native strains of freshwater microalgae were evaluated their biomass growth and lipid production in modified BBM medium. Chlamydomonas sp. TAI-2 had better biomass growth and higher lipid production than Desmodesmus sp.TAI-1. The optimal growth ...
Sikora Elżbieta - - 2012
Background. Commonly occurring diseases can have the origin in oxidative processes ongoing in the human body. Vegetables of Brassicaceae family are the essential sources of natural antioxidants, especially phenolic compounds, in the human diet. The research was aimed to estimate the content of phenolic compounds in se- lected vegetables and ...
Chung Ill-Min - - 2012
The seeds of the Coriandrum sativum were extracted and the essential oil composition and immunotoxicity effects were studied. The analysis of the essential oil was conducted by gas chromatography-mass spectroscopy, which revealed 33 components, representing 99.99% of the total oil from the seeds of coriander. The major components are linalool ...
Rosenberg Irwin H - - 2012
In the 1930s, Lucy Wills identified a 'new hemopoietic factor' in yeast and liver which cured tropical macrocytic anemia in humans and experimental anemia in monkeys. Janet Watson and William B. Castle named the unknown substance, which would ultimately become a form of folate, 'Wills' factor'. Further studies with this ...
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