Search Results
Results 351 - 400 of 1909
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Gupta Adarsha - - 2012
Marine microbes are competent organisms, some of which can accumulate large amounts of lipids. A yeast strain, Rhodotorula mucilaginosa AMCQ8A was isolated from the marine water of the Queenscliff region, Victoria, Australia. The yeast isolate was identified by sequencing 18s rDNA genes. Scanning electron microscopy images revealed scars on the ...
Souffriau Ben - - 2012
D-galacturonic acid is a major component of pectins but cannot be metabolized by Saccharomyces cerevisiae. It is assumed not to be taken up. We show that yeast displays surprisingly rapid low-affinity uptake of D-galacturonic acid, strongly increasing with decreasing extracellular pH and without saturation up to 1.5 M. There was ...
Liszt Kathrin Ingrid - - 2012
Wine may cause stomach irritation due to its stimulatory effect on gastric acid secretion, although the mechanisms by which wine or components thereof activate pathways of gastric acid secretion are poorly understood. We measured gastric pH with a non-invasive intra-gastric probe and demonstrated that administration of 125 ml white or ...
Yadav Rohan - - 2012
Here, we present the synthesis of two sialo-micelles to validate the significance of sialic acid orientation during specific carbohydrate-protein and carbohydrate-carbohydrate interactions. Our data clearly suggest that orientation of carboxylic acid and glycerol side chains of sialic acid moieties exert fine tuning of ligand-receptor interactions.
Musatti Alida - - 2012
The study was aimed at investigating the best biotransformation conditions to increase intracellular glutathione (GSH) levels in samples of baker's yeast (S. cerevisiae) employing either the commercially available compressed and dried forms. Glucose, GSH precursors amino acids, as well as other cofactors, were dissolved in a biotransformation solution and yeast ...
Jain Swati S - - 2012
Insulin-, and contraction-induced GLUT4 and fatty acid (FA) transporter translocation may share common trafficking mechanisms. Our objective was to examine the effects of partial Munc18c ablation on muscle glucose and FA transport, FA oxidation, GLUT4 and FA transporter (FAT/CD36, FABPpm, FATP1, FATP4) trafficking to the sarcolemma, and FAT/CD36 to mitochondria. ...
Xie Xiangxue - - 2012
The objective was to compare meat quality, muscle fiber characteristics, lipid oxidation and fatty acids of Limousin (LIM), Simmtental (SIM), Luxi (LX), Qinchuan (QC) and Jinnan (JN) offered the same diet in China. After finishing, eight bulls from each breed were randomly selected for slaughter at 18.5 months old. Longissimus ...
Dolezelova Pavlina - - 2012
The exact role of the central acidic domain of Mdm2 in p53 degradation remains unclear. We therefore performed a systematic and comprehensive analysis of the acidic domain using a series of short deletions and found that only a minor part of the domain was indispensable for Mdm2-mediated p53 ubiquitylation. Moreover, ...
Koshikari Yoshiki - - 2012
Reverse micelle-type N,N-diarylammonium pyrosulfate (3-5 mol %) efficiently catalyzes the hydrolysis of esters (up to 100 mmol scale) under organic solvent-free conditions. The present method is successfully applied to the hydrolysis of various esters without the decomposition of the base-sensitive moieties and without any loss of optical purity for α-heterosubstituted ...
Niu Huanqing - - 2012
Simultaneous determination of organic acids using ion-exclusion liquid chromatography and ultraviolet detection is described. The chromatographic conditions are optimized when an Aminex HPX-87H column (300 × 7.8 mm) is employed, with a solution of 3 mmol/L sulfuric acid as eluent, a flow rate of 0.4 mL/min and a column temperature ...
Lian Jieni - - 2012
The presence of very reactive C1-C4 molecules adversely affects the quality bio-oils produced from the pyrolysis of lignocellulosic materials. In this paper a scheme to produce lipids with Cryptococcus curvatus from the carboxylic acids in the pyrolytic aqueous phase collected in fractional condensers is proposed. The capacities of three oleaginous ...
Careaga Valeria P - - 2012
The edible sea cucumber Athyonidium chilensis is a fishery resource of high commercial value in Chile, but no information on its lipid and fatty acid composition has been previously reported. Phospholipids were the major lipid contents of the ethanolic extracts of tubules, internal organs and body wall of A. chilensis. ...
Galdieri Luciano - - 2012
Histone acetylation depends on intermediary metabolism for supplying acetyl-CoA in the nucleocytosolic compartment. However, because nucleocytosolic acetyl-CoA is also used for de novo synthesis of fatty acids, histone acetylation and synthesis of fatty acids compete for the same acetyl-CoA pool. The first and rate-limiting reaction in de novo synthesis of ...
Keunchkarian Sonia - - 2012
A chiral anion-exchanger stationary phase based on cinchonidine (CD) was developed. Two columns were packed with and without endcapping (EC) treatment (CD-chiral stationary phase[CD-CSP(EC)] and [CD-CSP], respectively) and studied for their ability to separate N-2,4-dinitrophenyl α-amino acids (DNP-amino acids) enantiomers over a temperature range of 10-40 °C with a hydro-organic ...
Gezici Orhan - - 2012
Organic matter present in lignite samples collected from different depths (i.e. top, mid and bottom) of lignite source, Ilgın, Konya province, was examined by using subtractive-FTIR-ATR spectroscopy. FTIR spectra were recorded on (i) original samples, (ii) the samples dried at 105°C and (iii) the samples acid-treated and dried. After a ...
Ikarashi Ryuichi - - 2012
Abstract Background. Various substances including uric acid, organic acids and drugs are transported by organic anion transporters (OATs) in the kidney. In addition, a member of the OAT family, urate transporter 1 (URAT1), is involved in the reabsorption of uric acid from the renal tubule. Benzbromarone inhibits URAT1 to block ...
Uemura Hiroshi - - 2012
Recently, many genes involved in the formation of unsaturated and polyunsaturated fatty acids (PUFAs) were isolated. In most cases, their activities were confirmed by expressing them in the well-studied model organism Saccharomyces cerevisiae because its fatty acid compositions are very simple and it does not contain PUFAs. Taking advantage of ...
Hua Wen Jin - - 2012
The aim of this study was to determine transepithelial transport characteristics of rosuvastatin and effect of ursolic acid (P-gp potential inhibitor) and ko143 (ABC transporters selective inhibitor) on its transport in Caco-2 monolayers. A reliable Caco-2 cell monolayers model was established. The TEER value was used to inspect integrity of ...
Noblet Audrey - - 2012
Abstract The search for organic molecules at the surface of Mars is a top priority of the next Mars exploration space missions: Mars Science Laboratory (NASA) and ExoMars (ESA). The detection of organic matter could provide information about the presence of a prebiotic chemistry or even biological activity on this ...
Oh Nam Muk - - 2012
In order to develop a novel functional poly(l-amino acid) that can dissolve in volatile organic solvents, we prepared poly[l-aspartic acid-g-(3-diethylaminopropyl)]-b-poly(ethylene glycol) [poly(l-Asp-g-DEAP)-b-PEG] via the conjugation of 3-diethylaminopropyl (DEAP) to carboxylate groups of poly(l-Asp) (M(n) 4K)-b-PEG (M(n) 2K). This poly(l-aspartic acid) derivative evidenced a relatively high solubility in volatile organic solvents ...
Berrocal Alexander - - 2012
Aims:  For Ophiostoma (Ceratocystis) ulmi the ability to undergo morphological change is a crucial factor for its virulence. To gain an understanding of quorum-sensing activity in O. ulmi as it relates to yeast-mycelium dimorphism control, the present study examines the effects of branched-chain amino acids as well as their fusel ...
Limwikrant Waree - - 2012
A new 2/1 carbamazepine (CBZ)/malonic acid (MA) cocrystal polymorph form C was formed using a vibrational rod mill, whereas the known cocrystal polymorph form A was prepared using a ball mill. IR measurements showed that the interaction between CBZ and MA in cocrystal form C was formed by amide-carboxylic acid ...
Apostolaki Angeliki - - 2012
Type I casein kinases are highly conserved among Eukaryotes. Of the two Aspergillus nidulans casein kinases I, CkiA is related to the δ/ε mammalian kinases and to Saccharomyces cerevisiae Hrr25p. CkiA is essential. Three recessive ckiA mutations leading to single residue substitutions, and downregulation using a repressible promoter, result in ...
Takeungwongtrakul Sirima - - 2012
Lipids from cephalothorax and hepatopancreas of Pacific white shrimp (Litopenaeus vannamei) stored in ice for up to 6days were extracted and characterised. The extraction yields of lipids from hepatopancreas (10.65-12.64%) were higher than those from cephalothorax (2.59-2.88%). However, no changes in the extraction yield were observed during the storage (p>0.05). ...
van Roermund Carlo W T - - 2012
Peroxisomes play a major role in human cellular lipid metabolism, including fatty acid β-oxidation. The most frequent peroxisomal disorder is X-linked adrenoleukodystrophy, which is caused by mutations in ABCD1. The biochemical hallmark of X-linked adrenoleukodystrophy is the accumulation of very long chain fatty acids (VLCFAs) due to impaired peroxisomal β-oxidation. ...
Pestana José M - - 2012
BACKGROUND: Consumer awareness regarding the intake of beef of organic origin is strongly associated with the beneficial outcomes to human health, the environment and animal welfare. In this paper the effects of slaughter season and muscle type on the fatty acid composition, conjugated linoleic acid (CLA) isomeric profile, total cholesterol, ...
Xu Wen - - 2012
Dicarboxylic acids are important products from photooxidation of volatile organic compounds and are believed to play an important role in the formation and growth of atmospheric secondary organic aerosols. In this paper, the interaction of five dicarboxylic acids, i.e., oxalic acid (C2H2O4), malonic acid (C3H4O4), maleic acid (C4H4O4), phthalic acid ...
Serafeimidou Amalia - - 2012
Many studies with conjugated linoleic acid (CLA) indicate that it has a protective effect against mammary cancer. Because dairy products are the most important dietary sources of CLA, we have investigated the CLA concentrations and additionally the fatty acid profiles and chemical composition of several commercial, traditional, Greek yogurts from ...
Li Tingfeng - - 2012
This review examines the mechanisms propelling cofactor-independent, organic cofactor-dependent and metal-dependent decarboxylase chemistry. Decarboxylation, the removal of carbon dioxide from organic acids, is a fundamentally important reaction in biology. Numerous decarboxylase enzymes serve as key components of aerobic and anaerobic carbohydrate metabolism and amino acid conversion. In the past decade, ...
Girard Luiza - - 2012
A pilot plant anaerobic/anoxic/oxic (A2/O) system fed with domestic wastewater was operated to examine the effect of varying different types of carbon source (acetic acid, propionic acid, and glucose), added as a complement to the wastewater, on the (1) process performance and (2) microbial population. The operational condition that lead ...
Trechot Philippe - - 2012
Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of nicorandil-induced ulceration and fistula into adjacent ...
Yuan Na - - 2012
A high-performance liquid chromatography with ultraviolet detection (HPLC-UV) is established for the simultaneous determination of p-phthalic acid, benzoic acid, 4-carboxybenzaldehyde, m-phthalic acid, o-phthalic acid, phthalide, o-toluic acid, m-toluic acid and p-toluic acid in the residue generated during the production of p-phthalic acid (PPA). On a narrow-diameter reversed-phase C18 column, gradient ...
Meinert Cornelia - - 2012
Light on chirality: To predict the enantiomeric enrichment that can be induced into racemic organic molecules with the help of circularly polarized light, the anisotropy factor g is essential. Anisotropy spectra g=f(λ) recorded for proteinaceous amino acids provide crucial information on the transfer of chirality from light to matter.
Nielsen Carsten Uhd - - 2012
The aim of the present study was to investigate the transport of γ-aminobutyric acid (GABA) across the basolateral membrane of intestinal cells. The proton-coupled amino acid transporter, hPAT1, mediates the influx of GABA and GABA mimetic drug substances such as vigabatrin and gaboxadol and the anticancer prodrug δ-aminolevulinic acid across ...
Palupi Eny - - 2012
As a contribution to the debate on the comparison of nutritional quality between conventional versus organic products, the present study would like to provide new results on this issue specifically on dairy products by integrating the last 3 years' studies using a meta-analysis approach with Hedges' d effect size method. ...
Fiori L - - 2012
Lipid profiles of fish oil extracted from trout heads, spines and viscera using supercritical carbon dioxide and Randall extraction with hexane were measured. The amount of unsaturated fatty acids (as a percentage of total fatty acids) was within the range of 72.6-75.3% in all the substrates. A significant presence of ...
Zobnina Valentina G - - 2012
Knowledge on noncovalent intermolecular interactions of organic polyethers with amino acids is essential to gain a better understanding on how polymers assemble in organic nanoparticles which are promising for drug delivery and cryoprotection. The main objective of the present study was to determine how polyethers assemble around ionizable amino acids ...
Bonfils Grégory - - 2012
The target of rapamycin complex 1 (TORC1) is an essential regulator of eukaryotic cell growth that responds to growth factors, energy levels, and amino acids. The mechanisms through which the preeminent amino acid leucine signals to the TORC1-regulatory Rag GTPases, which activate TORC1 within the yeast EGO complex (EGOC) or ...
Bureau Sylvie - - 2012
The objectives of this study were i) to test different conditions of freezing, thawing, and grinding during sample preparation and ii) to evaluate the possibility of using mid-infrared spectroscopy for analysing the composition of sugars, organic acids and polyphenols in apples. Seven commercial apple cultivars were chosen for their large ...
Schefer Larissa - - 2012
The self-assembly behavior of the naturally occurring steroidal bile compounds cholic, deoxycholic, ursodeoxycholic and lithocholic acids was studied by combining atomic force microscopy (AFM), polarized optical microscopy (POM), Fourier-transform infrared spectroscopy (FTIR), absorption spectroscopy (UV-Vis), circular dichroism (CD) and wide angle X-ray scattering (WAXS). Molecular solutions of these mono-, di- ...
Senphan Theeraphol - - 2012
Compositions and yield of lipids extracted from hepatopancreas of Pacific white shrimp (Litopenaeus vannamei) subjected to autolysis at 60°C for different times (0, 30, 60, 90 120 and 150min) were investigated. Extraction yield increased from 7.4% to 8.8% as autolysis time increased from 0 to 150min. Coincidental increase in total ...
El Ghenymy Abdellatif - - 2012
The mineralization of sulfanilic acid has been studied by electro-Fenton (EF) and photoelectro-Fenton (PEF) with UVA light using an undivided electrochemical cell with a boron-doped diamond (BDD) anode and an air diffusion cathode able to generate H2O2. Organics were then oxidized by hydroxyl radicals formed at the anode surface from ...
Cohen S - - 2012
Sweet melon cultivars contain a low level of organic acids and, therefore, the quality and flavor of sweet melon fruit is determined almost exclusively by fruit sugar content. However, genetic variability for fruit acid levels in the Cucumis melo species exists and sour fruit accessions are characterized by acidic fruit ...
Styan Katie E - - 2012
Organically modified layered silicates were incorporated intoa polyether soft segment polyurethane to form composites of at least delaminated morphology. The primary organic modifier was a quaternary ammonium compound, however one composite included an alternative aminoundecanoic acid-modified silicate. The composites' biostability was assessed in an in vivo ovine model over a ...
Koh Eunmi - - 2012
This study was undertaken to compare the levels of ascorbic acid, vitamin C, flavonoids, nitrate, and oxalate in 27 spinach varieties grown by certified organic and conventional cultivation practices. LC-ESI/MS/MS of methanolic extracts of spinach demonstrated 17 flavonoids including: glucuronides and acylated di- and triglycosides of methylated and methylenedioxyderivatives of ...
Qin Lei - - 2012
Previous studies indicated high xylose yield could be achieved after pretreatment using organic acids, but it is necessary to systematically investigate the effects of different parameters during organic acid pretreatments. Corn stover was pretreated with sulfuric, oxalic, citric, tartaric and acetic acid at 50 and 90mM from 130 to 190°C. ...
Hadj-Taieb Sameh - - 2012
Background: Inborn errors of metabolism are neglected in developing countries because they are not as common as infectious and nutritional disorders. In Tunisia, no information is available on the incidence and epidemiological features of these inherited metabolic diseases. Aims: To precise the profile of aminoacidopathies other than phenylketonuria and organic ...
Ganan M - - 2012
Yeast cell wall (YCW) preparations and yeast mannoprotein extracts have been effective against some enteropathogenic bacteria as Campylobacter jejuni, Escherichia coli, and Salmonella, and they can affect the population of beneficial lactic acid bacteria (LAB). In this work, we studied the effect of a mannoprotein extract on five strains of ...
Heuer Jan F - - 2012
ABSTRACT: INTRODUCTION: There is mounting evidence that injury to one organ causes indirect damage to other organs systems with increased morbidity and mortality. The aim of this study was to determine the effects of acid aspiration pneumonitis (AAP) on extrapulmonary organs and to test the hypothesis that these could be ...
Giovanola M - - 2012
K(+)-coupled amino acid transporter 1 (KAAT1) belongs to the NSS family of solute transporters and it is expressed in the midgut and in salivary glands of Manduca sexta larvae. As more than 80% of family members, KAAT1 shows a stretch of three glycines (G85-G87) that according to the structure of ...
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