Search Results
Results 351 - 400 of 2468
< 3 4 5 6 7 8 9 10 11 12 13 >
Xu Yun - - 2014
MON 87460 (D1) maize contains a gene that expresses the cold shock protein B (CSPB) from Bacillus subtilis to confer a yield advantage when yield is limited by water availability. This study evaluated the composition of grain from the D1-containing combined-trait maize hybrids: D1 × NK603, D1 × MON 89034 ...
Bera Anupam A Academy of Scientific and Innovative Research, Gijubhai Badheka Marg, Bhavnagar-364002 - - 2014
Production of polyhydroxyalkanoates (PHAs) from Jatropha biodiesel residues, namely crude glycerol and oil cake hydrolysate, has been reported previously. Halomonas hydrothermalis (MTCC accession no. 5445; NCBI Genbank accession no. GU938192), a wild marine strain, was used in the bio-synthesis. The present study was initiated to vary the properties of the ...
Souza Joanne M M JM Laboratório de Investigação Sistemática em Biotecnologia e Biodiversidade Molecular/LabISisBio, Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, Belém, PA, - - 2014
In this study, a protocol to induce high amount of friable callus of Boerhaavia paniculata RICH and a lipidomics technique were applied to investigate the profile of lipids to relate to those present in the roots of this plant that presented anti-inflammatory activity in the crude hexane extract. The callus ...
Ramalho Suelem D SD Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil, (phone: +55-16-33518061; fax: - - 2014
Cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents. Using a bioactivity-guided fractionation, a series of triterpenoids was identified as a new class of competitive inhibitors towards cathepsin L with affinity values in ...
Rao Y Poorna Chandra - - 2014
Fatty acids are known to influence the ability of macrophages to generate reactive oxygen species (ROS). However the effect of elaidic acid (EA, 18:1 trans fatty acid) on ROS generation is not well studied. Rat peritoneal macrophages were enriched with elaidic acid by incubating the cells with 80 1M EA. ...
Liu Li-Jia LJ School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, - - 2014
To study the absorption properties and mechanism of two important components, trolline and veratric acid, from the flowers of Trollius chinensis, in order to better understand the contribution of these two compounds to the effectiveness of these flowers. The human Caco-2 cell monolayer model was employed to study the transport ...
Shen Jie - - 2014
Abstract Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines. In this report, HPLC and measurement of antioxidant properties were used to describe the active ingredients of Salvia miltiorrhiza injection (SMI). HPLC results showed that tanshinol, protocatechuic aldehyde, rosmarinic acid, ...
Ahmed Dildar D Department of Chemistry, Forman Christian College (A Chartered University), Lahore 54600, Pakistan. Electronic address: - - 2014
To conduct a comparative analysis of the phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit. The dried methanolic extracts of mesocarp and epicarp of the fruit and their hexane, chloroform, ethyl acetate, n-butanolic and aqueous fractions were subjected to antioxidant assays including ferric ...
Iqbal Pervaiz P Department of Chemistry, Forman Christian College (A Chartered University), Lahore 54600, - - 2014
To evaluate antioxidant and radical scavenging activities of organic extracts from fruit, roots and aerial parts of Fagonia cretica. Shed dried and powdered plant parts were initially extracted in methanol and subsequently partitioned in n-hexane, chloroform, ethyl acetate and 1-butanol successively. Antioxidant and radical scavenging potential of the methanol extracts ...
Kim Su-Yeon SY Functional Food and Nutrition Division, Kalasalingam University, Tamil Nadu 600001, - - 2014
In the present report, the effects of blanching, steaming, and high temperature/high pressure processing (HTHP) on the amino acid contents of commonly consumed Korean root vegetables, leaf vegetables, and pulses were evaluated using an Automatic Amino Acid Analyzer. The total amino acid content of the samples tested was between 3.38 ...
Min Kyoung-Jin KJ Department of Immunology, School of Medicine, Keimyung University, Daegu, - - 2014
Carnosic acid, which is one of extract components of rosemary, has anti-inflammatory, anti-oxidant, and anti-cancer effects. However, the anti-cancer effect of carnosic acid in human renal carcinoma cells is unknown. Flow cytometry analysis was used to examine the effects of carnosic acid on apoptosis, and Asp-Glu-Val-Asp-ase activity assay kit was ...
Shirani Kobra K Department of Pharmacodynamy and Toxicology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. - - 2014
Ferula szowitsiana has been widely used for medicinal purposes around the world. The anti-oxidant effect of F. szowitsiana had been proved. The current study aims to determine the protective effects of galbanic acid, a sesquiterpene coumarin from F. szowitsiana, against hydrogen peroxide (H2O2) - induced oxidative DNA damage in human ...
Potumarthi Ravichandra R Bio Engineering and Environmental Center (BEEC), Indian Institute of Chemical Technology (CSIR), Tarnaka, Hyderabad, 500 607, India, - - 2014
Two commonly used chemical pretreatment processes, sulphuric acid, and sodium hydroxide, were tested to provide comparative performance data. A connection between solid to liquid ratio (S/L) and sugars released was observed with an increase in S/L ratio between 0.02 and 0.2. Enzymatic digestibility of 1 M of NaOH-pretreated corncobs were released ...
Yang Yishan Y Food Science & Technology Programme, Department of Chemistry, National University of Singapore, Science Drive 4, Singapore 117543, - - 2014
This study evaluated the acid and heat resistance of Salmonella Enteritidis in simulated gastric fluid (pH2.0) and during thermal treatment (54-60°C), respectively, after adaptation to lactic acid (LA) or trisodium phosphate (TSP) at various pHs (pH5.3-9.0). The changes in membrane lipid composition and expression levels of RpoS and RpoH were ...
Singer Stacy D - - 2014
BackgroundTraditional canola (Brassica napus L.; AACC, 2n¿=¿38) cultivars yield seed oil with a relatively high proportion of ¿-linolenic acid (ALA; C18:3 cis¿9,12,15), which is desirable from a health perspective. Unfortunately, due to the instability of this fatty acid, elevated levels also result in oils that exhibit a short shelf life ...
Li Xu X North Carolina State University; Purdue - - 2014
Plant secondary metabolism is an active research area because of the unique and important roles the specialized metabolites have in the interaction of plants with their biotic and abiotic environment, the diversity and complexity of the compounds and their importance to human medicine. Thousands of natural accessions of Arabidopsis thaliana ...
Cao Xiaolin X Drug Product Development, Amgen Inc., Thousand Oaks, California, - - 2014
We report, for the first time, the identification of fatty acid particles in formulations containing the surfactant polysorbate 20. These fatty acid particles were observed in multiple mAb formulations during their expected shelf life under recommended storage conditions. The fatty acid particles were granular or sand-like in morphology and were ...
Fan Ye Y The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education; School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, PR - - 2014
Unsaturated fatty acid liposomes (Ufasomes) have attracted interests because of the ready availability of unsaturated fatty acids and the simple assembly strategy. However, the colloidal instability of the ufasomes hinders them from applying in the fields of drug delivery and food additives. In the present work, conjugated linoleic acid (CLA) ...
Ornelas O O Department of Inorganic Chemistry and Materials Institute, University of Alicante, Apdo. 99- 03080, Alicante, Spain. - - 2014
The synthesis of nitrogenated carbon nanotubes (N-CNTs) with up to 6.1 wt% N, via the use of pyridine as the nitrogen containing carbon precursor, can provide a facile route to significantly enhance the low intrinsic specific capacitance of carbon nanotubes. The nitrogen functionalities determine this, at least, five-fold increase of ...
Moon Se-Kwon SK Changhae Advanced Institute of Technology, Changhae Ethanol Co., Ltd., Palbok-Dong 829, Dukjin-Gu, Jeonju, 561-203, Republic of - - 2014
The by-products of bioethanol production such as thin stillage (TS) and condensed distillers solubles (CDS) were used as a potential nitrogen source for economical production of lactic acid. The effect of those by-products and their concentrations on lactic acid fermentation were investigated using Lactobacillus paracasei CHB2121. Approximately, 6.7 g/L of yeast ...
Belkadhi Aïcha A Département de Biologie, Unité de Recherche de Physiologie et Biochimie de la tolérance des plantes aux contraintes abiotiques, Faculté des Sciences de Tunis, Campus Universitaire, 1060, Tunis, Tunisia, - - 2014
Interest in use of flax (Linum usitatissimum L.) as cadmium (Cd)-accumulating plant for phytoextraction of contaminated soils opened up a new and promising avenue toward improving tolerance of its varieties and cultivars to Cd stress. The aim of this study is to get insights into the mechanisms of Cd detoxification ...
Legrand-Poels Sylvie S University of Liege, GIGA-Signal Transduction, Laboratory of Virology and Immunology, Liege 4000, Belgium. Electronic address: - - 2014
Free fatty acids (FFAs) are metabolic intermediates that may be obtained through the diet or synthesized endogenously. In addition to serving as an important source of energy, they produce a variety of both beneficial and detrimental effects. They play essential roles as structural components of all cell membranes and as ...
Haag Nicola Leonard NL University of Hohenheim, State Institute of Agricultural Engineering and Bioenergy, Garbenstraße 9, Stuttgart 70599, Germany. Electronic address: - - 2014
A green biorefinery enables the material and energetic use of biomass via lactic acid and methane production. Different ensiling techniques were applied to maize and amaranth with the aim to increase the amount of lactic acid in the silage. In addition the methane formation potential of the ensiled samples and ...
Sepe Valentina - - 2014
Bile acids are signalling molecules interacting with the nuclear receptor FXR and the G-protein coupled receptor 1 (GP-BAR1/TGR5). GP-BAR1 is promising pharmacological target for the treatment of steato-hepatitis, type 2 diabetes and obesity. Endogenous bile acids and currently available semisynthetic bile acids are poorly selective toward GP-BAR1 and FXR. Thus, ...
Maher Amy Christine AC McMaster University - - 2014
In skeletal muscle the Rab-GTPase-activating protein TBC1D1 has been implicated in the regulation of fatty acid oxidation by an unknown mechanism. We determined whether TBC1D1 altered fatty acid utilization via changes in protein-mediated fatty acid transport and/or selected enzymes regulating mitochondrial fatty acid oxidation. We also determined the effects of ...
Kudoyarova Guzel R GR Institute of Biology, Ufa Science Centre, Russian Academy of Sciences, pr. Oktyabrya, 69, 450054 Ufa, Russia. Electronic address: - - 2014
Phytohormone production is one mechanism by which rhizobacteria can stimulate plant growth, but it is not clear whether the bacteria gain from this mechanism. The hypothesis that microbial-derived cytokinin phytohormones stimulate root exudation of amino acids was tested. The rhizosphere of wheat plants was drenched with the synthetic cytokinin trans-zeatin ...
Bone Simon M SM The University of New South Wales , Kensington, New South Wales 2052, - - 2014
Diagnostic tests performed in the field or at the site of patient care would benefit from using a combination of inexpensive, stable chemical reagents and simple instrumentation. Here, we have developed a universal "DNA-only Cascade" (DoC) to quantitatively detect target analytes with increased speed. The DoC utilizes quasi-circular structures consisting ...
Lian Sai S Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China. - - 2014
Hexokinase (HK)-catalyzed glucose phosphorylation plays an important role in the regulation of circulating glucose levels, so aberrant HK activity may result in various human diseases. Herein, we present a new strategy for highly sensitive detection of HK activity by use of Zr(4+)-coated magnetic beads (ZrMBs) for selective capture of HK-induced ...
Li Wei W Tasly R&D Institute, Tasly Pharmaceutical Co., Ltd., Tianjin 300410, - - 2014
Two new trimeric caffeic acids, named salvianolic acids T and U (1 and 2), were isolated from the underground part of Salvia miltiorrhiza. Their structures, consisting of three caffeic acid units, were determined based on extensive 1D- and 2D- spectroscopic analyses and electronic circular dichroism (ECD) calculations.
Wang Wenlian W College of Pharmaceutical Science, Soochow University, Suzhou, 215123, - - 2014
Five new ursane-type triterpenoidal saponins (1-5), together with five known ones (6-10), were isolated from the EtOH extract of the roots of Ilex cornuta. The structures of saponins 1-5 were elucidated as 19α-hydroxyurs-12-en-28-oic acid 3β-O-β-D-glucuronopyranoside (1), 19α-hydroxyurs-12-en-28-oic acid 3β-O-β-D-glucuronopyranoside-6-O-ethyl ester (2), 19α-hydroxyurs-12-en-28-oic acid 3β-O-α-L-arabinopyranosyl-(1→2)-β-D-glucuronopyranoside (3), 3β-O-[α-L-arabinopyranosyl-(1→2)-β-D-glucuronopyranosyl]-19α-hydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (4) ...
Chen Jian J Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China; Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, Ghent 9000, Belgium; Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009, - - 2014
The phytochemical investigation of natural products of Gynura divaricata led to the isolation of eleven caffeoylquinic acid derivatives. They were characterized by spectrometric methods as 5-O-caffeoylquinic acid (1), 5-O-p-coumaroylquinic acid (2), 5-O-feruloylquinic acid (3), methyl 5-O-caffeoylquinate (4), 3,4-dicaffeoylquinic acid (5), 3,5-dicaffeoylquinic acid (6), 4,5-dicaffeoylquinic acid (7), methyl 3,4-dicaffeoylquinate (8), methyl ...
Liu Wai-Nam WN Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, P.R. - - 2014
Conjugated linolenic acids (CLNAs) are a group of naturally occurring positional and geometrical isomers of the C18 polyunsaturated essential fatty acid, linolenic acid (LNA), with three conjugated double bonds (C18:3). Although previous research has demonstrated the growth-inhibitory effects of CLNA on a wide variety of cancer cell lines in vitro, their action mechanisms and ...
Zinati Zahra Z Department of Crop Production and Plant Breeding, Faculty of Agriculture, Shiraz University, Shiraz, Iran. Electronic address: - - 2014
α-linolenic acid (ALA) is the most frequent omega-3 in plants. The content of ALA is highly variable, ranging from 0 to 1% in rice and corn to >50% in perilla and flax. ALA production is strongly correlated with the enzymatic activity of omega-3 fatty acid desaturase. To unravel the underlying ...
Treder Adam P AP Département de Pharmacologie, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke , Sherbrooke, QC, Canada J1H - - 2014
The first application of aziridine aldehyde dimers in solid-phase synthesis is reported. The solid-supported disrupted Ugi condensation between an aziridine aldehyde dimer, isonitrile, and backbone-anchored amino acids delivered N-acyl aziridine intermediates, which were reacted with nucleophiles to yield the corresponding piperazinones. Subsequent cleavage from the resin provided a diverse set ...
Chaudhary Jai Prakash JP AcSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar 364002, Gujarat, India; Scale-Up & Process Engineering Unit, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar 364002, Gujarat, - - 2014
This paper reports a microwave assisted one pot facile synthesis of ester derivatives of agarose (Agr-GAEst) through chemical reaction of agarose (Agr) with gallic acid (GA), an organic acid found in many plants employing carbodiimide chemistry. Agr-GAEst was characterised by FT-IR, (13)C NMR spectroscopy, thermogravimetric analysis (TGA), DMA measurements, scanning ...
No Da Som DS Department of Food and Nutrition, Korea University, Seoul 136-703, Republic of Korea; BK21PLUS Program in Embodiment: Health-Society Interaction, Department of Public Health Sciences, Graduate School, Korea University, Seoul 136-703, Republic of - - 2015
Pinolenic acid (PLA) is a polyunsaturated fatty acid of plant origin. PLA has been successfully enriched according to a two-step process involving lipase-catalysed esterification and urea complexation. For the first step, the fatty acids present in pine nut oil were selectively esterified with lauryl alcohol using Candida rugosa lipase. Under ...
Abe Katsuya K Department of Applied Chemistry, Faculty of Engineering, Kogakuin University, 2665-1, Nakano-machi, Hachioji, Tokyo, 192-0015, Japan, - - 2014
Aerial algae are considered to be highly tolerant of and adaptable to severe conditions including radiation, desiccation, high temperatures, and nutrient deficiency, compared with those from aquatic habitats. There are considerable variations in the fatty acid (FA) composition of aerial microalgae from dry environments. A new species with a high ...
Cheng Xin X School of Food and Biological Engineering, Jiangsu University, Zhenjiang, 212013, - - 2014
Production of lactic acid bacteria (LAB) starter with raw material has received much scientific investigation, but little information is available on the influences of some trace elements on the growth and fermentative activity of LAB. Based on this fact, this paper aimed to investigate the effects of Mn(2+) on the ...
Dziomba Szymon S Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 107 Hallera Street, 80-416, Gdańsk, - - 2014
Derivatization is a frequently used sample preparation procedure applicable to the enhancement of analyte detection sensitivity. Amino acids mostly require derivatization prior to electrophoretic or chromatographic analysis, especially if spectrophotometric detection is used. This study presents an on-line preconcentration technique for derivatized amino acids. The sensitivity of the method was ...
Wang Yong Y Department of Bioengineering and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA. wayong@missouri.edu - - 2014
Nanopores provide a unique single-molecule platform for genetic and epigenetic detection. The target nucleic acids can be accurately analyzed by characterizing their specific electric fingerprints or signatures in the nanopore. Here we report a series of novel nanopore signatures generated by target nucleic acids that are hybridized with a probe. ...
Dyari Herryawan Ryadi Eziwar - - 2014
ω-3-17,18-Epoxyeicosapentaenoic acid decreases cell proliferation and activates apoptosis whereas its regioisomers stimulate growth. We evaluated synthetic ω-3 epoxides of saturated fatty acids as anti-proliferative and pro-apoptotic agents in MDA-MB-231 breast cancer cells. The epoxides, but not their urea, amide or carbamate isosteres, impaired ATP production, enhanced caspase-3 activity and activated ...
Zhu Yu-Peng - - 2014
While atmosphere is known to contain a significant fraction of organic substance and the effect of acetic acid to stabilize hydrated sulfuric acids is found to be close that of ammonia, the details about the hydration of (CH3COOH)(H2SO4)2 are poorly understood, especially for the larger clusters with more water molecules. ...
Wamberg Michael C - - 2014
The surface functionalization of fatty acid vesicles will allow their use as nanoreactors for complex chemistry. In this report, the tethering of several DNA conjugates to decanoic acid vesicles for molecular recognition and synthetic purposes was explored. Due to the structure highly dynamic nature, only one novel bola-amphiphile DNA conjugate ...
Morales Gabriel G Department of Chemical and Energy Tech, Chemical and Environmental Tech, Mechanical Tech and Analytical Chemistry, Universidad Rey Juan Carlos, C/Tulipan. s/n. E-28933, Móstoles, Madrid, Spain. - - 2014
Here we describe a simple route to creating conformal sulphated zirconia monolayers throughout an SBA-15 architecture that confers efficient acid-catalysed one-pot conversion of glucose to ethyl levulinate.
Lager Susanne S University of Cambridge - - 2014
Fatty acids are critical for normal fetal development, but may also influence placental function. We have previously reported that oleic acid (OA) stimulates amino acid transport in primary human trophoblast (PHTs) cells. In other tissues, saturated and unsaturated fatty acids have distinct effects on cellular signaling, for instance palmitic acid ...
Greco James A JA University of - - 2014
Diets high in saturated fatty acids (SFAs) are associated with the development of circadian dysregulation, obesity, and type 2 diabetes mellitus. Conversely, polyunsaturated fatty acids (PUFAs) have recently been identified to improve insulin sensitivity, reduce weight gain, and relieve obesity-induced inflammation. While saturated fatty acids, such as the prevalent dietary ...
Brink Hendrik Gideon - - 2014
Succinic acid is well established as bio-based platform chemical with production quantities expecting to increase exponentially within the next decade. Actinobacillus succinogenes is by far the most studied wild organism for producing succinic acid and is known for high yield and titre during production on various sugars in batch culture. ...
Gladine Cécile C INRA, UMR1019, UNH, CRNH Auvergne, Clermont-Ferrand, France, - - 2014
The omega-3 fatty acid docosahexaenoic acid (DHA) has potent anti-atherogenic properties but its mechanisms of action at the vascular level remain poorly explored. Knowing the broad range of molecular targets of omega-3 fatty acids, microarray analysis was used to open-mindedly evaluate the effects of DHA on aorta gene expression in ...
Wang Juan J Department of Environmental Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing 100083, - - 2014
Four types of straws, namely, soybean, wheat, corn, and rice, were used to investigate their feasibility for lactic acid production. These straws mainly comprised cellulose, hemicellulose, and lignin. After ammonia pretreatment, the cellulose content increased, contrary to the decrease in hemicellulose and lignin contents. Analytical results showed that the liquid ...
Fukushima Keijo K Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 4228526, - - 2014
Human parainfluenza virus type 1 (hPIV1) and type 3 (hPIV3) initiate infection by sialic acid binding. Here, we investigated sialic acid linkage specificities for binding and infection of hPIV1 and hPIV3 by using sialic acid linkage-modified cells treated with sialidases or sialyltransferases. The hPIV1 is bound to only α2,3-linked sialic ...
< 3 4 5 6 7 8 9 10 11 12 13 >