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Treder Adam P AP Département de Pharmacologie, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke , Sherbrooke, QC, Canada J1H - - 2014
The first application of aziridine aldehyde dimers in solid-phase synthesis is reported. The solid-supported disrupted Ugi condensation between an aziridine aldehyde dimer, isonitrile, and backbone-anchored amino acids delivered N-acyl aziridine intermediates, which were reacted with nucleophiles to yield the corresponding piperazinones. Subsequent cleavage from the resin provided a diverse set ...
Chaudhary Jai Prakash JP AcSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar 364002, Gujarat, India; Scale-Up & Process Engineering Unit, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar 364002, Gujarat, - - 2014
This paper reports a microwave assisted one pot facile synthesis of ester derivatives of agarose (Agr-GAEst) through chemical reaction of agarose (Agr) with gallic acid (GA), an organic acid found in many plants employing carbodiimide chemistry. Agr-GAEst was characterised by FT-IR, (13)C NMR spectroscopy, thermogravimetric analysis (TGA), DMA measurements, scanning ...
No Da Som DS Department of Food and Nutrition, Korea University, Seoul 136-703, Republic of Korea; BK21PLUS Program in Embodiment: Health-Society Interaction, Department of Public Health Sciences, Graduate School, Korea University, Seoul 136-703, Republic of - - 2015
Pinolenic acid (PLA) is a polyunsaturated fatty acid of plant origin. PLA has been successfully enriched according to a two-step process involving lipase-catalysed esterification and urea complexation. For the first step, the fatty acids present in pine nut oil were selectively esterified with lauryl alcohol using Candida rugosa lipase. Under ...
Abe Katsuya K Department of Applied Chemistry, Faculty of Engineering, Kogakuin University, 2665-1, Nakano-machi, Hachioji, Tokyo, 192-0015, Japan, - - 2014
Aerial algae are considered to be highly tolerant of and adaptable to severe conditions including radiation, desiccation, high temperatures, and nutrient deficiency, compared with those from aquatic habitats. There are considerable variations in the fatty acid (FA) composition of aerial microalgae from dry environments. A new species with a high ...
Cheng Xin X School of Food and Biological Engineering, Jiangsu University, Zhenjiang, 212013, - - 2014
Production of lactic acid bacteria (LAB) starter with raw material has received much scientific investigation, but little information is available on the influences of some trace elements on the growth and fermentative activity of LAB. Based on this fact, this paper aimed to investigate the effects of Mn(2+) on the ...
Dziomba Szymon S Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 107 Hallera Street, 80-416, Gdańsk, - - 2014
Derivatization is a frequently used sample preparation procedure applicable to the enhancement of analyte detection sensitivity. Amino acids mostly require derivatization prior to electrophoretic or chromatographic analysis, especially if spectrophotometric detection is used. This study presents an on-line preconcentration technique for derivatized amino acids. The sensitivity of the method was ...
Wang Yong Y Department of Bioengineering and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA. wayong@missouri.edu - - 2014
Nanopores provide a unique single-molecule platform for genetic and epigenetic detection. The target nucleic acids can be accurately analyzed by characterizing their specific electric fingerprints or signatures in the nanopore. Here we report a series of novel nanopore signatures generated by target nucleic acids that are hybridized with a probe. ...
Dyari Herryawan Ryadi Eziwar - - 2014
ω-3-17,18-Epoxyeicosapentaenoic acid decreases cell proliferation and activates apoptosis whereas its regioisomers stimulate growth. We evaluated synthetic ω-3 epoxides of saturated fatty acids as anti-proliferative and pro-apoptotic agents in MDA-MB-231 breast cancer cells. The epoxides, but not their urea, amide or carbamate isosteres, impaired ATP production, enhanced caspase-3 activity and activated ...
Zhu Yu-Peng - - 2014
While atmosphere is known to contain a significant fraction of organic substance and the effect of acetic acid to stabilize hydrated sulfuric acids is found to be close that of ammonia, the details about the hydration of (CH3COOH)(H2SO4)2 are poorly understood, especially for the larger clusters with more water molecules. ...
Wamberg Michael C - - 2014
The surface functionalization of fatty acid vesicles will allow their use as nanoreactors for complex chemistry. In this report, the tethering of several DNA conjugates to decanoic acid vesicles for molecular recognition and synthetic purposes was explored. Due to the structure highly dynamic nature, only one novel bola-amphiphile DNA conjugate ...
Morales Gabriel G Department of Chemical and Energy Tech, Chemical and Environmental Tech, Mechanical Tech and Analytical Chemistry, Universidad Rey Juan Carlos, C/Tulipan. s/n. E-28933, Móstoles, Madrid, Spain. - - 2014
Here we describe a simple route to creating conformal sulphated zirconia monolayers throughout an SBA-15 architecture that confers efficient acid-catalysed one-pot conversion of glucose to ethyl levulinate.
Lager Susanne S University of Cambridge - - 2014
Fatty acids are critical for normal fetal development, but may also influence placental function. We have previously reported that oleic acid (OA) stimulates amino acid transport in primary human trophoblast (PHTs) cells. In other tissues, saturated and unsaturated fatty acids have distinct effects on cellular signaling, for instance palmitic acid ...
Greco James A JA University of - - 2014
Diets high in saturated fatty acids (SFAs) are associated with the development of circadian dysregulation, obesity, and type 2 diabetes mellitus. Conversely, polyunsaturated fatty acids (PUFAs) have recently been identified to improve insulin sensitivity, reduce weight gain, and relieve obesity-induced inflammation. While saturated fatty acids, such as the prevalent dietary ...
Brink Hendrik Gideon - - 2014
Succinic acid is well established as bio-based platform chemical with production quantities expecting to increase exponentially within the next decade. Actinobacillus succinogenes is by far the most studied wild organism for producing succinic acid and is known for high yield and titre during production on various sugars in batch culture. ...
Gladine Cécile C INRA, UMR1019, UNH, CRNH Auvergne, Clermont-Ferrand, France, - - 2014
The omega-3 fatty acid docosahexaenoic acid (DHA) has potent anti-atherogenic properties but its mechanisms of action at the vascular level remain poorly explored. Knowing the broad range of molecular targets of omega-3 fatty acids, microarray analysis was used to open-mindedly evaluate the effects of DHA on aorta gene expression in ...
Wang Juan J Department of Environmental Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing 100083, - - 2014
Four types of straws, namely, soybean, wheat, corn, and rice, were used to investigate their feasibility for lactic acid production. These straws mainly comprised cellulose, hemicellulose, and lignin. After ammonia pretreatment, the cellulose content increased, contrary to the decrease in hemicellulose and lignin contents. Analytical results showed that the liquid ...
Fukushima Keijo K Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 4228526, - - 2014
Human parainfluenza virus type 1 (hPIV1) and type 3 (hPIV3) initiate infection by sialic acid binding. Here, we investigated sialic acid linkage specificities for binding and infection of hPIV1 and hPIV3 by using sialic acid linkage-modified cells treated with sialidases or sialyltransferases. The hPIV1 is bound to only α2,3-linked sialic ...
Kachrimanidou Vasiliki V Department of Food Science and Human Nutrition, Agricultural University of Athens, Iera Odos 75, 118 55 Athens, - - 2014
Polyhydroxybutyrate (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] production was developed in bioreactor cultures using the strain Cupriavidus necator DSM 7237 cultivated on crude glycerol, sunflower meal (SFM) hydrolysates and levulinic acid as the sole fermentation feedstocks. Bacterial growth and PHB production was influenced significantly by the free amino nitrogen and inorganic phosphorus ...
Chen Tai-Yuan TY Department of Food Science, National Taiwan Ocean University, No. 2, Pei-Ning Road, Keelung, Taiwan, - - 2015
This study investigated the inhibitory effects of aqueous extracts from Miracle Fruit leaves (AML) on mutation and oxidative damage. The results showed that AML in the range of 1-5mg/plate inhibited the mutagenicity of 2-aminoanthracene (2-AA), an indirect mutagen, and 4-nitroquinoline-N-oxide (4-NQO), a direct mutagen toward Salmonella typhimurium TA 98 and ...
Wahl Oliver O University of Würzburg, Institute for Pharmacy and Food Chemistry, Würzburg 97074, - - 2014
Magnesium supplementation in form of organic magnesium salts is a very popular practice. We examined the enantiomeric purity of "Magnesium aspartate dihydrate" monographed in the European Pharmacopeia. A chiral capillary zone electrophoresis using (2-hydroxypropyl)-β-cyclodextrin coupled to laser induced fluorescence detection and a HPLC-fluorescence method with chiral derivatization using o-phthaldialdehyde and ...
Pang Ka-Lai KL Institute of Marine Biology and Center of Excellence for the Oceans, National Taiwan Ocean University, 2 Pei-Ning Road, Keelung, 20224, Taiwan, Republic of China, - - 2014
Polyunsaturated fatty acids (PUFAs) are fatty acids with more than one double bond in the chemical structure. Arachidonic acid (ARA, 20:4 (n-6)) and eicosapentaenoic acid (EPA, 22:5 (n-3)) are common PUFAs with beneficial health effects. Marine fish and meat are the main sources of omega-3 and omega-6 fatty acids in ...
Wang Xiaojuan X Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, 88 Xuefu Road, Kunming, 650223, - - 2014
Sacha inchi (Plukenetia volubilis L., Euphorbiaceae) seed oil is rich in α-linolenic acid, a kind of n-3 fatty acids with many health benefits. To discover the mechanism underlying α-linolenic acid accumulation in sacha inchi seeds, preliminary research on sacha inchi seed development was carried out from one week after fertilization ...
Tang Xin X State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 LiHu Road, Wuxi, 214122, Jiangsu, People's Republic of China, - - 2014
Twenty standard amino acids were examined as single nitrogen source on the growth, total fatty acids production, and yield of γ-linolenic acid (GLA) in Mucor circinelloides. Of the amino acids, tyrosine gave the highest biomass and lipid accumulation and thus resulted in a high GLA yield with respective values of ...
Imman Saksit S The Joint Graduate School for Energy and Environment (JGSEE), King Mongkut's University of Technology Thonburi, Prachauthit Road, Bangmod, Bangkok 10140, - - 2014
In this study, effects of homogeneous acid and alkali promoters on efficiency and selectivity of LHW pretreatment of rice straw were studied. The presences of acid (0.25%v/v H2SO4, HCl, H3PO4, and oxalic acid) and alkali (0.25w/v NaOH) efficiently promoted hydrolysis of hemicellulose, improved enzymatic digestibility of the solids, and lower ...
Takahashi Mariko M Division of Marine Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan, Minato-ku, Tokyo 108-8477, - - 2015
The formation of molybdosilicate in the molybdate yellow method is elucidated by ESI-MS. Polymeric silicic acids were hydrolyzed to monomers, and molybdosilicates with a Keggin structure were formed. Each step of the formation reaction of molybdosilicate from molybdic and silicic acids between pH 1 and 2 was clarified by ESI-MS ...
Pirro Valentina V Department of Chemistry, University of Turin, Via Pietro Giuria 7, Turin 10125, Italy. Electronic address: - - 2014
The development of sensitive measurements to analyze individual cells is of relevance to elucidate specialized roles or metabolic functions of each cell under physiological and pathological conditions. Lipids play multiple and critical roles in cellular functions and the application of analytical methods in the lipidomics area is of increasing interest. ...
Zhou Shengfei S Department of Biological System Engineering, University of Wisconsin, Agricultural Engineering Building, Madison, WI 53706, USA. Electronic address: - - 2014
The concept of co-production of liquid fuel (ethanol) along with animal feed on farm was proposed, and the strategy of using ambient-temperature acid pretreatment, ensiling and washing to improve ethanol production from alfalfa stems was investigated. Alfalfa stems were separated and pretreated with sulfuric acid at ambient-temperature after harvest, and ...
Wendlinger Christine - - 2014
Furan fatty acids (F-acids) are valuable antioxidants containing a furan moiety in the central part of the molecule. They occur in the lipids of different foodstuff and plants, with grass being the main source for their presence in milk fat and butter. Since cows from organic farming receive higher portions ...
Canbay Erhan E Department of Biochemistry, Faculty of Science, Ege University, 35100 Bornova-İzmir, Turkey. Electronic address: - - 2015
The aim of this study was mainly to develop a microbial biosensor for the simultaneous determination of lactic acid and pyruvic acid. In developing biosensor, lyophilised Lactobacillus delbruecki sp. bacterial cells were immobilised with polypyrrole on a platin electrode surface using electropolymerization method. Lactate concentration was determined based on the ...
Ahn Hee-Jeong HJ Department of Food and Biotechnology, Korea University, Sejong 339-700, Republic of - - 2015
A mutant derived from a cyclodextrin glucantransferase with an alanine residue as its acid/base catalyst residue (CGT-E284A) catalyzed regioselective glycosylation at 3-OH of l-ascorbic acid using α-maltosyl fluoride (αG2F) and l-ascorbic acid as the donor and acceptor, respectively, yielding 3-O-α-maltosyl-l-ascorbate (AA3αG2). The optimum conditions were determined by high-performance liquid chromatography ...
Newsome Seth D SD *Biology Department, University of New Mexico, Albuquerque, NM 87131, USA; Environment and Natural Resource Institute, University of Alaska-Anchorage, Anchorage, AK 99508, USA; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; and School of Natural Sciences, University of California-Merced, Merced, CA 95343, USA - - 2014
Stable-isotope analysis (SIA) has revolutionized animal ecology by providing time-integrated estimates of the use of resources and/or habitats. SIA is based on the premise that the isotopic composition of a consumer's tissues originates from its food, but is offset by trophic-discrimination (enrichment) factors controlled by metabolic processes associated with the ...
Hiltunen Minna M Department of Biology, University of Eastern Finland, P.O. Box 111, 80101, Joensuu, Finland, - - 2014
We studied the copepod Limnocalanus macrurus for seasonal variation in the composition of fatty acids, wax esters and sterols in large boreal lakes, where it occurs as a glacial-relict. Vast wax ester reserves of Limnocalanus were accumulated in a period of only two months, and comprised mono- and polyunsaturated fatty ...
Barati Danial D Biomimetic Materials and Tissue Engineering Laboratory, Department of Chemical Engineering, University of South Carolina, Columbia, SC 29208, - - 2014
The objective of this work was to investigate the effect of chemical composition and segment number (n) on gelation, stiffness, and degradation of hydroxy acid-chain-extended star polyethylene glycol acrylate (SPEXA) gels. The hydroxy acids included glycolide (G,), L-lactide (L), p-dioxanone (D) and -caprolactone (C). Chain-extension generated water soluble macromers with ...
Torrinha Alvaro - - 2014
Octopus vulgaris, Octopus maya and Eledone cirrhosa from distinct marine environments [Northeast Atlantic (NEA), Northwest Atlantic (NWA), Eastern Central Atlantic, Western Central Atlantic (WCA), Pacific Ocean and Mediterranean Sea] were characterized regarding their lipid and vitamin E composition. These species are those commercially more relevant worldwide. Significant interspecies and inter-origin ...
Lichtenstein Alice H AH JM USDA Human Nutrition Research Center, Tufts University, 711 Washington Street, Boston, MA, 02111, USA, - - 2014
Dietary trans double bond containing fatty acids have been associated with increased risk of cardiovascular disease. There are two main sources of dietary trans fatty acids: meat and dairy fats, and partially hydrogenated fats. Because of a number of factors, including changes in federal labeling requirements for packaged foods, and ...
Lopez-Villalobos Nicolas N Institute of Veterinary, Animal and Biomedical Sciences, Massey University,Palmerston North,New - - 2014
The objective of this study was to estimate heritability and crossbreeding parameters (breed and heterosis effects) of various fatty acid (FA) concentrations in milk fat of New Zealand dairy cattle. For this purpose, calibration equations to predict concentration of each of the most common FAs were derived with partial least ...
Hwang J A JA Department of Animal Science and Technology, Sunchon National University, Suncheon 540-742, - - 2014
The study was designed to evaluate the effect of 2% seamustard (Undaria pinnatifida) by-product (SW) on growth performance, immunity, carcass characteristics, cholesterol content and fatty acid profile in Hanwoo steers. A total of 20 Hanwoo steers (ave. 22 months old; 619 kg body weight) were randomly assigned to control (basal ...
Cao Xing-Fen XF State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, - - 2014
To study the chemical constituents and bioactivity of the stem bark of Mitragyna diversifolia. Compounds were isolated by various chromatographic methods. Their structures were elucidated on the basis of spectroscopic techniques (IR, UV, MS, and NMR), and they were evaluated for their cytotoxic activities by the MTT method. Eight triterpenes ...
Liu Xin X Institute of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, Hubei, China; Hubei Collaborative Innovation Center for Processing of Agricultural Products, Wuhan Polytechnic University, Wuhan 430023, Hubei, - - 2014
Melamine in combination with cyanuric acid has been considered to be more toxic than either melamine or cyanuric acid alone. The objective of this study was designed to evaluate the combined genotoxicity and cytotoxicity of melamine (M) and cyanuric acid (C) at three mass ratios (1:1, 1:2, 2:1). MC (1:1), ...
Ma Huijuan H Department of Endocrinology and Metabolism, Hebei General Hospital, Shijiazhuang, Hebei 050051, - - 2014
Bile acids are increasingly recognized as key regulators of systemic metabolism. While bile acids have long been known to play important and direct roles in nutrient absorption, bile acids also serve as signalling molecules. Bile acid interactions with the nuclear hormone receptor farnesoid X receptor (FXR) and the membrane receptor ...
Zhang Weisan - - 2014
Recent studies have found that triterpene acid type compounds has many effects including antiinflammatory, regulating blood sugar level, antiviral and antitumor activity. More importantly, triterpene acid type compounds has become one of the most popular topics recently because its selective toxic effects on cancer cells and harmless to normal cells ...
Wen Yaya - - 2014
A new acorane sesquiterpene glucoside, 1R,3S,4R,5R,10R-3,10-dihydroxyacoronene-3-O-beta-D-gluc-oside (1), was isolated from the EtOAc-soluble partition of the ethanol extract of Lysionotus pauciflorus, together with six known compounds, namely p-hydroxybenzoic acid (2), vanillic acid (3). caffeic acid (4). beta-hydroxypropiosyringone (5), alpha,beta-dihydroxypropiosyringone (6), and lyoniresinol (7). The structure of the new compound was elucidated ...
Khouni Lyes - - 2014
Three new anthranilic acid derivatives: N-(R)-3'-hydroxydocosanoylanthranilic acid (1), N-(R)-3'-hydroxytricosanoylanthranilic acid (2) and N-(R)-3'-hydroxytetracosanoylanthranilic acid (3), in addition to one knownanthranilic acid and six known flavonoids, were isolated from the ethyl acetate extract of Ononis pusilla L. The structures of the isolated compounds were assigned by spectroscopic methods, including 1D and ...
Truong Tuong L - - 2014
From Usnea aciculifera, a new depside aciculiferin A (1) was isolated, together with eleven known compounds, (+)-(12R)-usnic acid (2), methyl haematommate (3), methyl beta-orsellinate (4), methyl orsellinate (5), atranol (6), 7-hydroxy-5-methoxy-6-methylphthalide (7), norstictic acid (8), stictic acid (9), atranorin (10), barbatinic acid (11) and diffractaic acid (12). Their chemical structures ...
Kaewpiboon Chutima C Department of Biology, Faculty of Science, Thaksin University, Phatthalung 93110, - - 2014
Cancer cells have the ability to develop resistance to chemotherapy drugs, which then leads to a reduced effectiveness and success of the treatment. Multidrug resistance (MDR) involves the resistance in the same cell/tissue to a diverse range of drugs of different structures. One of the characteristics of MDR is an ...
Kim Jin Nam JN Department of Food Science and Nutrition, The Catholic University of Korea, Bucheon, Republic of - - 2014
Phytic acid, also known as myo-inositol hexaphosphate, has been shown to lower blood glucose levels and to improve insulin sensitivity in rodents. We investigated the effects of phytic acid and myo-inositol on differentiation, insulin-stimulated glucose uptake, and lipolysis of adipocytes to test the hypothesis that the antidiabetic properties of phytic ...
Fan Xiaoguang X State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR - - 2014
Corncob residue is a cellulose-rich byproduct obtained from industrial xylose production via dilute acid hydrolysis processes. Enzymatic hydrolysis of cellulose in acid hydrolysis residue of corncob (AHRC) is often less efficient without further pretreatment. In this work, the process characteristics of acid impregnated steam explosion were studied in conjunction with ...
Finn Kristen Lawler KL Rutgers, The State University of New Jersey, Cranford, New Jersey - - 2014
Background: Soybean oil lipid emulsion may compromise immune function and promote hepatic damage due to its composition of long-chain fatty acids, phytosterols, high proportion of ω-6 fatty acids, and low α-tocopherol levels. Combination lipid emulsions have been developed using medium-chain triglyceride oil, fish oil, and/or olive oil, which provide adequate ...
Lai Thi Ngoc Ha TN Institut des Sciences de la Vie, UCLouvain, Belgium; Faculty of Food Sciences and Technology, Vietnam National University of Agriculture, Viet - - 2015
In this study, detailed chemical properties of sim (Rhodomyrtus tomentosa (Ait.) Hassk.) fruit including nutritional composition, phenolic content and antioxidant capacity were determined for the first time. A 150g serving of sim fruit contained high levels of dietary fibre (69.94-87.43% of Recommended Daily Intake (RDI)), α-tocopherol (38.90-51.87% RDI), manganese (>100% ...
Gonçalves Ana Teresa AT Laboratory of Biotechnology and Aquatic Genomics, Interdisciplinary Center for Aquaculture Research (INCAR), University of Concepción, P.O. Box 160-C. Chile. Electronic address: - - 2014
The goal of this study was to identify and analyze the lipid metabolic pathways involved in energy production and ecdysteroid synthesis in the ectoparasite copepod Caligus rogercresseyi. Massive transcriptome sequencing analysis was performed during the infectious copepodid larval stage, during the attached chalimus larval stage, and also in female and ...
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