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Xiao Han H State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang 550025, PR China; School of Chemistry and Environmental Science, Guizhou Minzu University, Guiyang 550025, PR - - 2014
Here, a series of β-amino acid ester derivatives containing quinazoline and benzothiazoles was synthesized and evaluated for anti-tobacco mosaic virus (TMV) activity. The compounds 3n, 3o, 3p and 3q showed good antiviral activity against TMV at a concentration of 500μg/mL, with curative rates of 55.55%, 52.32%, 52.77% and 50.91%, respectively, ...
Song Zhimei Z Department of Pharmaceutical Engineering, School of Biological Science and Technology, University of Jinan, 336 Nanxinzhuang Xilu, Jinan, Shandong Province 250022, PR - - 2014
In this study, a novel linolenic acid-modified poly(ethylene glycol)-b-poly(ϵ-caprolactone) copolymer was prepared through radical addition, ring-opening polymerization, and N-acylation reactions. Its structure was characterized by (1)H NMR and GPC. Micelles were developed by thin-film hydration and used as a delivery system for curcumin with high drug loading capacity of 12.80% ...
Tian Li-Wen LW Eskitis Institute, Griffith University, Brisbane, QLD 4111, - - 2014
High throughput screening of a pre-fractionated natural product library identified 11 active fractions showing ApoE modulation activity. Mass-directed fractionation of one active crude extract from the Australian marine sponge Callyspongia sp. resulted in the isolation of 13 metabolites, including three new bromotyrosine derivatives, callyspongic acid (1), 3,5-dibromo-4-methoxyphenylpyruvic acid (2), N-acetyl-3-bromo-4-hydroxylphenylethamine ...
Han Hyoung Soon - - 2014
A simple method has adapted to prepare MWCNT grafted Poly(lactic acid) (MWCNT-g-PLA) by intercalative polymerization of poly(lactic acid) in the presence of multi-wall carbon nanotubes (MWCNT) functionalized with hydroxyl groups. The functionalized MWCNT has obtained from the treatment of methylene diphenyl diisocyanate (MDI) with MWCNT, and then the reaction with ...
de Godoy M R C MR Department of Animal Sciences - - 2014
The objective of this research was to measure in vitro hydrolytic digestion, glycemic and insulinemic responses in dogs, and true ME (TMEn) content of select soluble corn fibers (SCF) in roosters. The first generation (G1) SCF included hydrochloric acid-treated corn syrup (G1-CS-HCl), an SCF with an increased total dietary fiber ...
Thiruvengadam M M Konkuk University Department of Applied Bioscience, College of Life and Environmental Science Seoul 143 701 South - - 2014
Phenolic contents and antioxidant capacities from different solvent extracts (petroleum ether, ethyl acetate, methanol, butanol and water) of Aster scaber leaf were investigated. Antioxidant activity was evaluated by three different methods, namely DPPH radical scavenging activity, reducing power assay and phosphomolybdenum activity. A total of twenty-three polyphenolic compounds were identified ...
Innocente Adrine Maria AM Laboratório de Fitoquímica, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Porto Alegre, RS, - - 2014
Trichomonas vaginalis is a flagellated parasite that causes trichomonosis, the most common non-viral sexually transmitted disease (STD) in the world. Worryingly, trichomonosis is associated to increased transmission of HIV. Due to high frequency of the infection during pregnancy and the development of metronidazole-resistant isolates, therapeutic alternatives to 5-nitroimidazole are being ...
Komatsu Reina R Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, - - 2014
Stereochemical assignment of amino acids and corresponding codons or anticodons has not been successful so far. Here, we focused on proline and GGG (anticodon of tRNA(Pro)) and investigated their mutual interaction. Circular dichroism spectroscopy revealed that guanosine nucleotides (GG, GGG) formed G-quartet structures. The structures were destroyed by adding high ...
Lee In-Kyu IK Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, - - 2014
The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and glucose, which is controlled by the PDC. The PDC converts pyruvate, coenzyme A (CoA), and ...
Sekito Takayuki T a Laboratory of Molecular Physiology and Genetics, Faculty of Agriculture , Ehime University , Matsuyama , - - 2014
Basic amino acids (lysine, histidine and arginine) accumulated in Saccharomyces cerevisiae vacuoles should be mobilized to cytosolic nitrogen metabolism under starvation. We found that the decrease of vacuolar basic amino acids in response to nitrogen starvation was impaired by the deletion of AVT4 gene encoding a vacuolar transporter. In addition, ...
Krzyśko-Łupicka Teresa T Department of Biotechnology and Molecular Biology, Faculty of Natural and Technical Sciences, University of Opole, Kard. B. Kominka 6a, 45-035, Opole, - - 2014
This study was aimed at investigating the physicochemical and microbiological changes that took place during the ageing process of spent bleaching earth in the presence of autochthonous microorganisms. Research material included fresh spent bleaching earth (SBE0) and the same material after 3 years of storage at the constant temperature of 20 °C, ...
Harman Christopher C Norwegian Institute for Water Research, Oslo, - - 2014
Polar organic chemical integrative samplers (POCIS) were deployed in the vicinity of an offshore oil installation and analysed for naphthenic acids (NA). POCIS accumulated a range of mono to tetracyclic NA, with different degrees of alkylation, with monocyclic acids being the most abundant. POCIS or similar polar samplers may currently ...
Wang Jian J Department of Pharmaceutics, School of Pharmacy, Key Laboratory of Smart Drug Delivery, Ministry of Education, Fudan University, 826 Zhangheng Road, Shanghai, 201203, - - 2014
Viscoelasticity is a useful parameter for characterizing the intrinsic properties of the cross-linked polyacrylate hydrogel used in cataplasm bases. The aim of this study was to investigate the effects of various formulation parameters on the rheological characteristics of polyacrylate hydrogel. The hydrogel layers were formed using a partially neutralized polyacrylate ...
Tatsumi Kenta K Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. tfuji@scl.kyoto-u.ac.jp - - 2014
Palladium-catalyzed formal arylacylation of allenes using acid chlorides and arylboronic acids has been achieved. The reaction afforded the corresponding α,β-unsaturated ketones regio- and stereoselectively.
Choi Jong-Il JI Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju, 500-757, South Korea, - - 2014
In this study, a high lipid-accumulating mutant strain of the microalgae Scenedesmus dimorphus was developed via radiation breeding. To induce mutant strain, S. dimorphus was gamma-irradiated at doses from 100 to 800 Gy, and then a mutant (Sd-Pm210) with 25 % increased lipid content was selected using Nile red staining methodology. Sd-Pm210 ...
Xiong Xunyu X Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, China; College of Chemistry & Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, - - 2014
We have developed a rapid method that allows us to characterize the binding interaction of sulfobutylether-β-cyclodextrin (SBE-β-CD) with five therapeutically important phenolic acids: ferulic acid, caffeic acid, gallic acid, protocatechuic acid and vanillic acid. The method utilizes a flow-injection chemiluminescence (FI-CL) technique that relies on the inhibition of a cyclodextrin-luminol ...
Follonier Stéphanie S University of Applied Sciences and Arts Western Switzerland Valais (HES-SO Valais-Wallis), Institute of Life Technologies, Route du Rawyl 47, 1950 Sion, - - 2014
Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are biobased and biodegradable alternatives to petrol-derived polymers, whose break-through has been prevented by high production cost. Therefore we investigated whether wastes from the food industry (9 types of fruit pomace including apricots, cherries and grapes, and waste frying oil) could replace the costly sugars and fatty ...
Moertelmaier Christoph C Karlsruhe Institute of Technology (KIT), Institute of Biology for Engineers and Biotechnology of Wastewater, Am Fasanengarten, D-76128 Karlsruhe, Germany. Electronic address: - - 2014
Volatile fatty acid (VFA) metabolism and population changes during re-start of a wet anaerobic digester for treatment of biowaste suspensions were investigated. Initially acetate and propionate accumulated. However, VFA degradation rates improved within 2weeks, reaching a balanced metabolism with constantly low VFA concentrations. The total microbial population consisted of 60% ...
Tan Jin J Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin 300134, People's Republic of - - 2014
Design of chemical sensor arrays that can discriminate real-world samples has been highly attractive in recent years. Herein a fluorescent indicator-displacement sensor array for discrimination of fresh fruit juices was developed. By coupling the unique high affinity of titania to electron-donating anions and the cross-reactivity of molecularly imprinted materials to ...
Badjah Hadj Ahmed A Yacine - - 2014
A simple method has been described for simultaneous determination of phenolic acids, flavonoids and other phenols contents in various natural honey samples collected from various regions of Yemen. Multiwalled carbon nanotubes were used as solid phase adsorbent for extraction of the polyphenols from honey samples. The total content of phenolic ...
Tressler Caitlin M - - 2014
(2S,4R)- and (2S,4S)-perfluoro-tert-butyl-4-hydroxyproline were synthesized (as Fmoc-, Boc-, and free amino acids) in 2-5 steps. The key step of each synthesis was a Mitsunobu reaction with perfluoro-tert-butanol, which incorporated a perfluoro-tert-butyl group, with 9 chemically equivalent fluorines. Both amino acids were incorporated in model alpha-helical and polyproline helix peptides. Each ...
Lu Jin J School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, - - 2014
Seven sesquiterpenes, including four α-cedrene type (Shellolic acid A-C, Laccishellolic acid), two R-curcumene type (Shellolic acid D-E) and Shellolic acid F were isolated from Shellac, of which six were unknown. Their structures were elucidated by HR-ESI-MS, UV, IR, 1D and 2D NMR methods. The absolute configurations were confirmed via the ...
Ye Lingzhen L Agronomy Department, Zhejiang University, Hangzhou 310029, People's Republic of - - 2014
Our previous study found that the critical protein in SE (silica eluted) proteins is BTI-CMe, and assumed that SE-ve malt for brewing may improve the haze stability in beer. In this study, we investigated the difference in gene sequence and corresponding amino acid sequence of BTI-CMe between SE+ve and SE-ve ...
Wu Chien-Hui CH Department of Food Science, National Taiwan Ocean University, No. 2, Pei-Ning Road, Keelung 202, Taiwan, R. O. - - 2014
One-step sulfuric acid saccharification of the red alga Pterocladiella capillacea was optimized and the detoxification methods of neutralization, overliming, and electrodialysis for its acid hydrolysate were evaluated for fermentability using the thermotolerant yeast Kluyveromyces marxianus. Proximate composition analysis indicated that P. capillacea was rich in carbohydrates. A significant galactose recovery ...
Haun William W Cellectis plant sciences Inc., New Brighton, MN, - - 2014
Soybean oil is high in polyunsaturated fats and is often partially hydrogenated to increase its shelf life and improve oxidative stability. The trans-fatty acids produced through hydrogenation pose a health threat. Soybean lines that are low in polyunsaturated fats were generated by introducing mutations in two fatty acid desaturase 2 ...
Yang Xufei X Department of Agricultural and Biological Engineering, University of Illinois at Urbana-Champaign, 1304 West Pennsylvania Avenue, Urbana, IL 61801, USA. Electronic address: - - 2014
Airborne particles are known to serve as a carrier of odors emanating from concentrated animal feeding operations (CAFOs). However, limited quantitative data about particle-borne odorants preclude an accurate assessment of the role of particles in odor transport. This study collected total suspended particulates (TSP) and PM10 (particles with aerodynamic diameter ...
Singh Jyoti J School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110 067, India. Electronic address: - - 2014
The present investigation evaluates the potential of an endolithic cyanobacterium isolated from marble rock to utilize sodium bicarbonate (NaHCO3) as carbon source for prospective recycling of CO2 into biodiesel. Microalgae thriving on marble were cultured and subjected to increasing NaHCO3 concentration. The most competent isolate was identified and characterized in ...
Andersen Stephen J - - 2014
Short chain carboxylates such as acetate are easily produced through mixed culture fermentation of many biological waste streams, though routinely digested to biogas and combusted rather than harvested. We developed a pipeline to extract and upgrade short chain carboxylates to esters, via membrane electrolysis and biphasic esterification. Carboxylate rich broths ...
Saeed Aamer A a Department of Chemistry , Quaid-I-Azam University , Islamabad 45320 , - - 2014
Total synthesis of trilepisiumic acid (4-((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-3-hydroxybenzoic acid) isolated from Trilepisium madagascariense was carried out. Doebner condensation of 3,4-dimethoxybenzaldehyde with malonic acid yielded 3,4-dimethoxycinnamic acid (2). Esterification of the latter with vanillin afforded 4-formyl-2-methoxyphenyl-3-(3,4-dimethoxy phenyl)acrylate (3) followed by permanganate oxidation in acidic medium provided the corresponding acid 4. Finally, demethylation of ...
Mihály Johanna J Departments of Biochemistry and Molecular Biology, University of Debrecen, Debrecen, - - 2014
Fatty acid concentrations, in particular n-3 and n-6 polyunsaturated fatty acids (PUFAs), have been described to be dysregulated in atopic dermatitis (AD) patients. The role of genetic polymorphisms of fatty acid enzymes in AD is controversial. We determined in a Hungarian cohort of healthy volunteers (n = 20) and AD ...
Souza Juliana L S JL Laboratory of Microbiology, Postgraduate Program in Biochemistry and Bioprospection, Federal University of Pelotas (UFPel) - Gonçalves Chaves, 457/702, 96015-560 Pelotas, RS, - - 2014
The secretion of extracellular phospholipases and proteinases of Candida has been described as a relevant virulence factor in human infections. Aliphatic fatty acids have antimicrobial properties, but the mechanism by which they affect the virulence factors of microorganisms, such as Candida, is still unclear, and there are a few reports ...
Zhou Xiao-Jing XJ National Engineering Laboratory for Tree Breeding, College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China; Beijing Key Laboratory of Forest Food Processing and Safety, College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China; Beijing Center for Physical and Chemical Analysis, Beijing 100089, - - 2014
A total of 11 phenolic compounds, as well as sucrose (12) and tryptophan (13), were isolated from cold-pressed Perilla frutescens var. arguta seed flour using column chromatography, and their chemical structures were identified as 3'-dehydroxyl-rosmarinic acid-3-o-glucoside (1), rosmarinic acid-3-o-glucoside (2), rosmarinic acid (3), rosmarinic acid methyl ester (4), luteolin (5), ...
Verhoff Moritz M Department for Pharmaceutical Analytics, Pharmaceutical Institute, University of Tuebingen , Auf der Morgenstelle 8, D-72076 Tuebingen, - - 2014
The microsomal prostaglandin E2 synthase (mPGES)-1 is the terminal enzyme in the biosynthesis of prostaglandin (PG)E2 from cyclooxygenase (COX)-derived PGH2. We previously found that mPGES-1 is inhibited by boswellic acids (IC50 = 3-30 μM), which are bioactive triterpene acids present in the anti-inflammatory remedy frankincense. Here we show that besides ...
Basak Shibaji S Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata - 700 032, India. - - 2014
A pyridine containing amino acid based gelator forms gel in aqueous media in the presence of hydrochloric acid and the chloride ion is found to be very selective for gelation. The gelator is successfully applied for the detection and trapping of hydrogen chloride gas and this indicates its probable application ...
Allefeld Nadine N Centrum für Molekulare Materialien, Fakultät für Chemie, Anorganische Chemie, Universität Bielefeld, Universitätsstraße 25, 33615 Bielefeld - - 2014
This paper describes the synthesis of unsymmetrically substituted phosphinous acids and phosphane oxides featuring at least one electron-withdrawing pentafluoroethyl group. The presence of a diethylamino function as a protecting group allows a selective reaction of RClPNEt2 (R=CF3 , C6 F5 , C6 H5 ) with LiC2 F5 . On treatment ...
Voynikov Yulian Y Faculty of Pharmacy, Medical University of Sofia, str. Dunav 2, Sofia 1000, - - 2014
A series of amides were synthesized by condensation of theophylline-7-acetic acid and eight commercially available amino acid methyl ester hydrochlorides. Consecutive hydrolysis of six of the amido-esters resulted in the formation of corresponding amido-acids. The newly synthesized compounds were evaluated for their in vitro activity against Mycobacterium tuberculosis H37Rv. The ...
Aamelfot Maria M Norwegian Veterinary Institute, PO Box 750 Sentrum, 0106, Oslo, - - 2014
Sialic acids are located at the terminal branches of the cell glycocalyx and secreted glycan molecules. O-Acetylation is an important modification of the sialic acids, however very few studies have demonstrated the in situ distribution of the O-Acetylated sialic acids. Here the distribution of glycoprotein bound 4-O-Acetylated sialic acids (4-O-Ac ...
Baer Marcel D - - 2014
For strong acids, like hydrochloric acid, the complete dissociation into an excess proton and conjugated base as well as the formation of independent solvated charged fragments is assumed. The existence of chloride-hydronium (Cl-H3O+) contact ion pairs even in moderate concentration hydrochloric acid (2.5 m) demonstrates that the counter ions do ...
Mita Tsuyoshi T Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, - - 2014
A catalytic enantioselective silylation of N-tert-butylsulfonylimines using a Cu-secondary diamine complex was demonstrated. The resulting optically active α-amino silanes could be carboxylated under a CO2 atmosphere (1 atm) to afford the corresponding α-amino acids in a stereoretentive manner. This two-step sequence provides a new synthetic protocol for optically active α-amino ...
Kang Lin-Zhi LZ Department of Bioengineering, College of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe, Guangzhou 510640, China; China National Engineering Research Center of Juncao Technology, China; Institute of Biomass Research, South China Agricultural University, Guangzhou 510640, - - 2014
Two strains of transgenic Flammulina velutipes TF71 and TF7H with 4cl and rs genes with the capability to produce resveratrol were obtained. In the nutrition assessment and analysis of transgenic strain and original strain (F7), the amino acid composition and proximate compositions of fruiting bodies were determined by amino acid ...
Gubitosi Marta - - 2014
The introduction of a mannose residue on carbon 3 of lithocholic acid gives rise to an asymmetric and rigid bolaamphiphilic molecule, which self-assembles in water forming elongated tubular aggregates with an outer diameter of about 20 nm. These tubular structures display a temporal evolution, where the average tube diameter decreases ...
Pradhan Roshan R College of Pharmacy, Yeungnam University, 214-1, Dae-Dong, Gyongsan, 712-749, South - - 2014
In the present study, we developed the novel 17-allyamino-17-demethoxygeldanamycin (17-AAG)-loaded poly(lactic acid-co-glycolic acid) (PLGA) nanoparticles (NPs) using the combination of sodium lauryl sulfate and poloxamer 407 as the anionic and non-ionic surfactant for stabilization. The PLGA NPs were prepared by emulsification/solvent evaporation method. Both the drug/polymer ratio and phase ratio ...
Zhai Changwei C Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, and Department of Chemistry, East China Normal University , 3663 North Zhongshan Road, Shanghai 200062, - - 2014
A simple metal-free method for the synthesis of 3-aryloxindoles via Brønsted acid catalyzed aromatic C-H functionalization of electron-rich arenes with 3-diazooxindoles is developed. In the presence of a catalytic amount of TfOH, a series of 3-aryloxindoles are synthesized as single regioisomers in good to excellent yields. This transformation is proposed ...
Zheng Xiao-Wei XW Laboratory of Food Microbiology, Wageningen University, P.O. Box 17, 6700 AA Wageningen, The Netherlands; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address: - - 2014
Chinese Daqu is used as a starter for liquor and vinegar fermentations. It is produced by solid state fermentation of cereal-pulse mixtures. A succession of fungi, lactic acid bacteria and Bacillus spp. was observed during the production of Daqu. Mesophilic bacteria followed by fungi, dominated the first phase of fermentation. ...
Dhakal Krishna Hari KH School of Applied Biosciences, Kyungpook National University, Daegu 702-701, Republic of - - 2014
Oleic acid and oleic acid rich foods may have beneficial health effects in humans. Soybeans with high oleic acid (around 80% in seed oil) have been developed. Soybean sprouts are an important vegetable in Korea, Japan and China. The objective of this study was to investigate the variation of unsaturated ...
Moreira Ana Paula B AP Institute of Biology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, - - 2014
Three novel isolates (A-354(T), A-328, and A-384) were retrieved from apparently healthy scleractinian Madracis decactis in the remote St Peter & St Paul Archipelago, Mid-Atlantic Ridge, Brazil. The novel isolates formed a distinct lineage based on the phylogenetic reconstruction using the 16S rRNA and pyrH gene sequences. They fell into ...
Dubey Mrigendra M Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, U.P., India. - - 2014
Two chiral structural isomers have been synthesized by molecular engineering of l-tartaric acid. In the presence of LiOH isomer forms a thermally stable, fluorescent gel which exhibits interesting nano-cluster morphology, anomalous optical and rheological properties whilst forms a non-fluorescent solution under similar conditions. The current-voltage (I-V) curve followed a non-linear ...
El-Ansari Omar O Department of Cell and Systems Biology, University of Toronto, Mississauga, ON, Canada, L5L - - 2014
The ability of the freshwater alga, Chlorella kessleri, to maintain a carbon concentrating mechanism when grown at acid pH was investigated. The alga grows over the pH range 4.0 to 9.0 and was found to take up bicarbonate and CO2 actively when grown at pH 6.0. However, when grown at ...
Kim Chang-Kwon CK Natural Products Research Institute, College of Pharmacy, Seoul National University , San 56-1, Sillim, Gwanak, Seoul 151-742, - - 2014
The suvanines, a new suvanine salt, five new (2, 4-8) and two known sesterterpenes from the same structural class, and two new modified lipids (9 and 10) were isolated from a Coscinoderma sp. sponge collected from Chuuk Island, Micronesia. On the basis of the results of combined spectroscopic and chemical ...
López Gina G Unidad de Saneamiento y Biotecnología Ambiental, Departamento de Biología, Pontificia Universidad Javeriana, POB 56710, Bogotá, DC, - - 2014
Several thermo- and mesoacidophilic bacterial strains that revealed high lipolytic activity were isolated from water samples derived from acidic hot springs in Los Nevados National Natural Park (Colombia). A novel lipolytic enzyme named 499EST was obtained from the thermoacidophilic alpha-Proteobacterium Acidicaldus USBA-GBX-499. The gene estA encoded a 313-amino-acid protein named ...
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