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Niedermaier Inga - - 2013
A mechanistic study: In a Brønsted acid/base reaction, gaseous triflic acid (OTfH) transfers its proton to the basic Cl(-) anion of the ionic liquid [C8 C1 Im]Cl forming volatile HCl and the IL [C8 C1 Im][TfO]. This anion exchange reaction is monitored in the near-surface region quantitatively by X-ray photoelectron ...
Tsushima Yu Y From the Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, - - 2013
Obesity is often accompanied by hyperuricemia. However, purine metabolism in various tissues, especially regarding uric acid production, has not been fully elucidated. Here we report, using mouse models, that adipose tissue could produce and secrete uric acid through xanthine oxidoreductase (XOR) and that the production was enhanced in obesity. Plasma ...
Al-Harrasi Ahmed - - 2013
A new boswellic acid derivative, 11α-ethoxy-β-boswellic acid (EBA; 1) and a new ursane-type triterpene, named nizwanone (2), were isolated from Omani frankincense Boswellia sacra Flueck. together with two known compounds papyriogenin B and rigidenol. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis using (1) H- and ...
Takagi Shiaki - - 2013
A bovine myeloid antimicrobial peptide antimicrobial peptide (BMAP-28) is a member of the cathelicidin family and acts as a component of innate immunity. There are few reports of susceptibility difference of methicillin-resistant Staphylococcus aureus (MRSA) and susceptible strains (MSSA) against BMAP-28. This study aims to clarify how a few amino ...
Prawatsri Saowanee - - 2013
Investigation of the constituents of the whole plant of Hyptis suaveolens led to the isolation of three new abietane diterpenes, isosuaveolic acid (1), 8α,9α-epoxysuaveolic acid (2), and 14-O-methylsuaveolic acid (3), together with eleven known compounds. The structures of 1-3 were established by spectroscopic methods and chemical correlations. Some isolates were ...
Noh Hwa Jung - - 2013
We report the synthesis of biogenic silver nanoparticles using chlorogenic acid as a bioreducing agent. Chlorogenic acid is a polyphenol compound abundant in coffee. UV-Vis spectra showed the characteristic surface plasmon resonance band at 415 nm, indicating the successful synthesis of biogenic silver nanoparticles. Spherical and irregular shaped nanoparticles were ...
Song Qin - - 2013
In an effort to identify hemostatic components from Liparis nervosa (Thunb.) Lindl. using a bioactivity-guided fractionation approach, the n-BuOH extract was found to promote ADP-induced platelet aggregation and two compounds were isolated from the active extract. Compound 1 was a new nervogenic acid glycoside and the structure was elucidated as ...
Huber Dirk - - 2013
Massive transfusion (MT) can cause severe electrolyte and acid-base disturbances in neonates and infants due to the unphysiological composition of packed red blood cells (PRBCs). Washing of the PRBCs using Cell Saver systems prior to MT is recommended for this reason. The composition of normal saline (NaCl), the standard wash ...
Furtado Ricardo A - - 2013
Biotransformation of 16alpha,17-epoxy-ent-kaurane-19-oic acid (1) by Beauveria sulfurescens ATCC 7159-F led to the production of a new ent-kaurane diterpenoid, 7beta,17-dihydroxy-ent-kaur-15-en-19-oic acid (7), and four other ent-kauranes (8 - 11), all of which were identified as their methyl esters. Compounds 9 and 10 were found to be new stereoisomers. Structures of ...
Pradhan Roshan - - 2013
In the present study, we developed novel docetaxel (DTX)-loaded polylactic acid-co-glycolic acid (PLGA) nanoparticles (NPs) using the combination of sodium lauryl sulfate (SLS) and poloxamer 407, the anionic and non-ionic surfactants respectively for stabilization. The NPs were prepared by emulsification/solvent evaporation method. The combination of these surfactants at weight ratio ...
Gaivelyte Kristina - - 2013
Our research aim was to investigate the quantitative composition of neochlorogenic acid, chlorogenic acid, rutin, hyperoside and isoquercitrin in leaves and fruit of introduced rowan plants to Lithuania using a HPLC method. In leaf and fruit samples, quantitative estimation of neochlorogenic acid (in leaf samples 1.11-11.49 mg/g, in fruit samples ...
Reina Raquel - - 2013
The physicochemical and sensory properties of 30 dry-cured hams and 30 dry-cured shoulders were analyzed to determine the relationships between them. The variables used to characterize both products were: compositional parameters, instrumental texture, amino acid and fatty acid composition, and sensory profile. Despite being products from the same animal and ...
Athanasakis Georgios - - 2013
Abstract The fruiting bodies of the edible mushroom Lactarius salmonicolor (Russulaceae) collected from the wild were extracted with solvents of increasing polarity and evaluated for their antioxidant capacity by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. Additionally, their total phenolic content was evaluated by a modification of the Folin-Ciocalteu method. The methanol ...
Pasquina Lincoln W LW Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, United - - 2013
The relentless spread of antibiotic-resistant pathogens makes it imperative to develop new chemotherapeutic strategies to overcome infection. The bacterial cell wall has served as a rich source for both validated and unexploited pathways that are essential for virulence and survival. Lipoteichoic acids (LTAs) and wall teichoic acids (WTAs) are cell ...
van Buijtenen Jeroen - - 2013
Furfural and acetic acid are produced with approximately 60 and 90 mol % yield, respectively, upon stripping bagasse with a gaseous stream of HCl/steam and condensing the effluent to water/furfural/acetic acid. The reaction kinetics is 1(st)  order in furfural and 0.5(th)  order in HCl. A process concept with full recycling of the ...
Zhang Fang - - 2013
Gasification of waste to syngas (H2/CO2) is seen as a promising route to a circular economy. Biological conversion of the gaseous compounds into a liquid fuel or chemical, preferably medium chain fatty acids (caproate and caprylate) is an attractive concept. This study for the first time demonstrated in-situ production of ...
Figueiredo-González M - - 2014
Sweet wines are traditionally elaborated in Galicia (the N.W. corner of Spain). The denomination of origin (DO) Valdeorras, one of the five DOs in Galicia, wants to promote the production and marketing of new sweets wines. The first one is made with dried red grapes Vitis vinifera L. Garnacha Tintorera ...
Mosley Luke M - - 2013
Large-scale exposure of acid sulfate soils during a hydrological drought in the Lower Lakes of South Australia resulted in acidification of surface water in several locations. Our aim was to describe the techniques used to monitor, assess and manage these acidification events using a field and laboratory dataset (n = 1,208) of ...
Cattoor Ko - - 2013
In this study, the in vitro metabolism of hop-derived bitter acids was investigated. Besides their well-known use as bitter compounds in beer, in several studies, bioactive properties are related to these types of molecules. However, scientific data on the ADME aspects of these compounds is limited. More specific in this ...
Bedics Matthew A - - 2013
Chalcogenopyrylium monomethine dyes were prepared via condensation of a 4-methylchalcogenopyrylium compound with a chalcogenopyran-4-one bearing a 4-(diethoxyphosphoryl)phenyl substituent (or the phosphonic acid derivative). The dyes have absorbance maxima of 603 - 697 nm in the window where the solar spectrum is most intense. The dyes formed H-aggregates on TiO2, increasing ...
Park Eul-Soo - - 2013
Isopropylamine is an ideal amino donor for reductive amination of carbonyl compounds by ω-transaminase (ω-TA) owing to its cheapness and high volatility of a ketone product. Here we developed asymmetric synthesis of unnatural amino acids via ω-TA-catalyzed amino group transfer between α-keto acids and isopropylamine.
van Berkel Sander S - - 2013
β-Lactam antibiotics react with penicillin binding proteins (PBPs) to form relatively stable acyl-enzyme complexes. We describe structures derived from the reaction of piperacillin with PBP3 (Pseudomonas aeruginosa) including not only the anticipated acyl-enzyme complex, but also an unprecedented complex with (5S)-penicilloic acid, which was formed by C-5 epimerization of the ...
Hanashima Shinya - - 2013
Oligo/polysialic acids consisting of consecutive α(2,8)-linkages on gangliosides and glycoproteins play a role in cell adhesion and differentiation events in a manner that is dependent on the degree of polymerization (DP). Anti-oligo/polysialic acid antibodies often have DP-dependent antigenic specificity, and such unique antibodies are often used in biological studies for ...
Fu Xiaobo - - 2013
Biodiesel production from microalgae is recognized as one of the best solutions to deal with the energy crisis issues. However, after the oil extraction from the microalgae, the microalgae residue was generally discarded or burned. Here a novel carbon-based solid acid catalyst derived from microalgae residue by in situ hydrothermal ...
Kumari Rajni - - 2013
The paper deals with the exploitation of Ipomoea carnea as a feedstock for the production of bioethanol. Dilute acid pretreatment under optimum conditions (3 %H2SO4, 120 °C for 45 min) produced 17.68 g L(-1) sugars along with 1.02 g L(-1) phenolics and 1.13 g L(-1) furans. A combination of overliming and activated charcoal adsorption facilitated the removal of 91.9 % ...
Cho Seunghee S Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, - - 2013
Cyanuric acid is synthesized industrially and forms during the microbial metabolism of s-triazine herbicides. Cyanuric acid is metabolized by some microorganisms via cyanuric acid hydrolase (CAH), which opens the s-triazine ring as a prelude to further metabolism. CAH is a member of the rare cyanuric acid hydrolase/barbiturase family. Here, the ...
Barbé Florence - - 2014
This study aimed at determining the kinetics of milk protein digestion and amino acid absorption after ingestion by six multi-canulated mini-pigs of two gelled dairy matrices having the same composition, similar rheological and structural properties, but differing by their mode of coagulation (acidification/renneting). Duodenal, mid-jejunal effluents and plasma samples were ...
Mantzourani I - - 2014
Sourdough breads prepared with kefir grains resulted in appearance of rope spoilage at the 15th day of bread storage, while the control samples (sourdough breads prepared with wild microflora) were spoiled approximately at the 7th day. Denaturing Gradient Gel Electrophoresis (DGGE) analysis confirmed the above macroscopic observation since Bacillus spp. ...
Nie Zhi-Kui - - 2013
A three-stage fermentation strategy was designed for efficient arachidonic acid (ARA)-rich oil production by Mortierella alpina. The process at different stages by changing the components of medium was investigated. In the first stage, mycelia were inoculated in a nutrient-rich medium for rapid propagation. In the second stage, mycelia were collected ...
Obied Hassan K - - 2013
During the extraction of canola oil, large quantities of meal are produced. Extracting biophenols from Australian canola meal ACM adds value to otherwise a low value agro-industrial by-product. We studied biophenol content and the antioxidant activity of ACM, the impact of extraction conditions and varietal differences. Sinapine was the principal ...
Ahn Mija - - 2013
Here we report for the first time the synthesis of Histidine (His) derived lipo-amino acids having pendant lipid tails at N(τ)- and N(π)-positions on imidazole group of His and applied it into synthesis of lipo-peptides. The attachment of His-derived lipo-amino acid into the very short inactive cationic peptides endows potent ...
Xiong Xu-Jie - - 2013
A MEKC method with LIF detection has been developed for the determination of seven neurotransmitter amino acids using 1,3,5,7-tetramethyl-8-(N-hydroxysuccinimidyl butyric ester)difluoroboradiaza-S-indacene as the labeling reagent. After derivatization at room temperature for 30 min, the seven target neurotransmitter amino acids including glycine, alanine, γ-aminobutyric acid, taurine, glutamine, glutamic acid and aspartic ...
Nakashima Anna A Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi 753-8515, - - 2013
Green leaf volatiles (GLVs) consisting of six-carbon aldehydes, alcohols, and their esters, are biosynthesized through the action of fatty acid hydroperoxide lyase (HPL), which uses fatty acid hydroperoxides as substrates. GLVs form immediately after disruption of plant leaf tissues by herbivore attacks and mechanical wounding and play a role in ...
Lu Yan - - 2013
Abstract Context: The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited. Objective: Elucidation of the cytotoxic constituents of S. pubescens was performed. Methods: Repeated ...
O'Gorman Aoife - - 2013
The use of metabolomic based techniques to aid oocyte and embryo selection has gained attention in recent years. Previous work from our laboratory has demonstrated that the 1H NMR based metabolic profile of follicular fluid correlates with oocyte developmental potential. Patients undergoing IVF at the Merrion Fertility Clinic had follicular ...
Wolf Matthew Bernard - - 2013
A cellular compartment was added to our previous mathematical model of steady-state acid-base and fluid-electrolyte chemistry to gain further understanding and aid diagnosis of complex disorders involving cellular involvement in critically-ill patients. An important hypothesis to be validated was that the thermodynamic, standard free-energy of cellular H(+) and Na(+) pumps ...
Borase Hemant P - - 2013
The present work provides scientific support on the use of latex of Ficus carica to synthesize stable silver nanoparticles (AgNPs). AgNPs synthesized immediately after the addition of latex to silver nitrate solution at room temperature. Synthesized nanoparticles were of spherical shape with average size of 163.7 nm. Fourier transform infrared spectroscopy ...
Yang X-Y - - 2013
To evaluate the possibility of elephant grass acid hydrolysate converting into bacterial cellulose (BC) produced by Gluconacetobacter xylinus CH001 and to characterize the morphology and structure of the cellulose produced. Acid-hydrolysed and detoxified elephant grass acid hydrolysate was inoculated with G. xylinus CH001. After 14 days of static fermentation, about 6·4 g l(-1) of ...
Chen Jinhui - - 2013
New phenstatin-fatty acid conjugates have been synthesized and tested against the KB-3-1, H460, MCF-7 and HEK293 cell lines, with an increase in anti-proliferative activity being observed at the micro-molar level paralleling an increase in un-saturation in the fatty acid component.
Noisier Anaïs F M - - 2013
An efficient synthesis of racemic or optically active α-amino acids by modified-Mitsunobu alkylation of a racemic or chiral glycine template from alcohols was developed. Libraries of amino acids were prepared in moderate to good yield with good to high enantioselectivity. This simple method widens the scope for preparation of structurally ...
Zarabi Maryam Farahnak MF Department of Chemistry, Faculty of Sciences, Zanjan University, Zanjan, Islamic Republic of Iran ; Department of Pilot Nanobiotechnology, Pasteur Institute of Iran, Tehran, Islamic Republic of - - 2014
We report a novel strategy for the synthesis and capping of gold nanoparticles (GNPs) by tryptophan, glutamic acid and aspartic acid. The ratio of chloroaurate ions to amino acid was optimized in the reaction medium to obtain monodispersed GNPs. The size of nanoparticles and size distribution were controlled by sodium ...
Mamadalieva Nilufar - - 2013
In the present study, chloroform extract obtained from aerial parts of Scutellaria ramosissima was phytochemically investigated. A non-polar fraction was obtained from the chloroform extract and the chemical composition of this fraction was identified by GC-MS. The major components of the non-polar fraction of S. ramosissima were determined as heneicosane ...
Bare Grant A L - - 2013
A template tetra-coupled with thymidylic acid through a phosphate-linkage was characterized in methanol for emergent properties of nucleobase tetrad formation. Intramolecular hydrogen bonded basepairing in the absence of cation was indicated for the thymidylic acid species supporting a monomeric template-assembled structure. Thus, an initial report of a stabilized individual thymine ...
Kajiwara Takashi - - 2013
A new lanthanoid porous coordination polymer, La-BTTc (BTTc = benzene-1,3,5-tris(2-thiophene-5-carboxylate)), was synthesized and structurally characterized to have densely aligned one-dimensional open metal sites, which were found to act as strong Lewis acid sites after the removal of the coordinated solvent.
Onar A Nur - - 2014
The seeds of grass pea (Lathyrus sativus L.), a drought tolerant crop, were analysed for quantitative determination of the free amino acids β-N-oxalyl-l-α,β-diaminopropionic acid (β-ODAP), homoarginine and asparagine by a simple and fast capillary electrophoretic method. In boric acid (80mM, pH 8.0) running buffer system, not only were α and ...
Valegård Karin - - 2013
Structural and biochemical studies of the orf12 gene product (ORF12) from the clavulanic acid (CA) biosynthesis gene cluster are described. Sequence and crystallographic analyses reveal two domains: a C-terminal penicillin-binding protein (PBP)/β-lactamase-type fold with highest structural similarity to the class A β-lactamases fused to an N-terminal domain with a fold ...
Tsuda Yuichi - - 2013
The properties of hydrolyzed feather keratin (HFK) were compared to those of hydrolyzed wool keratin (HWK) with the aim of developing better ways to utilize feather keratin waste. Amino acid analysis showed that HFK contained more hydrophobic amino acids did than HWK. Although gel permeation chromatography indicated that HFK and ...
Sugimoto Kazuhiko - - 2013
In Arabidopsis thaliana, the main route of cyclic electron transport around PSI is sensitive to antimycin A, but the site of inhibition has not been clarified. We discovered that ferredoxin-dependent plastoquinone reduction in ruptured chloroplasts was less sensitive to antimycin A in Arabidopsis that overaccumulated PGR5 originating from Pinus taeda ...
Jadhav Jyoti R - - 2013
A series of N-cholesteryl amino acid conjugates have been synthesized using a reductive amination protocol in good yield and purity. All the synthesized conjugates were evaluated for their in vitro antimicrobial activities against Gram positive and Gram negative bacteria. Among the conjugates tested, N-cholesteryl GABA 12 showed the highest potency ...
Bröer Stefan - - 2013
Epithelial neutral amino acid transporters have been identified at the molecular level in recent years. Mouse models have now established the crucial role of these transporters for systemic amino acid homeostasis. This review summarizes recent progress in this field. Epithelial neutral amino acid transporters play an important role in the ...
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