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Mogana R R School of Pharmacy, Faculty of Science, Center for Natural and Medicinal Products Research, University of Nottingham (Malaysia Campus), Jalan Broga, 43500 Semenyih, Selangor, - - 2014
In continuation of our natural and medicinal research programme on tropical rainforest plants, a bioassay guided fractionation of ethanolic extract of leaves of Canarium patentinervium Miq. (Burseraceae Kunth.) led to the isolation of scopoletin (1), scoparone (2), (+)-catechin (3), vomifoliol (4), lioxin (5), and syringic acid (6). All the compounds ...
Schulze Ines I Institute of Process Engineering in Life Sciences, Section II: Technical Biology, Karlsruhe Institute of Technology, Engler-Bunte-Ring 1, Karlsruhe, 76131, - - 2014
The yeast strains Cryptococcus podzolicus, Trichosporon porosum and Pichia segobiensis were isolated from soil samples and identified as oleaginous yeast strains beneficial for the establishment of microbial production processes for sustainable lipid production suitable for several industrial applications. When cultured in bioreactors with glucose as the sole carbon source C. ...
Loo Joo Ling JL Department of Food Science, Faculty of Food Science and Technology, University Putra Malaysia, 43400 Serdang, Malaysia. - - 2014
Mycelium-bound lipase (MBL), from a locally isolated Geotrichum candidum strain, was produced and characterized as a natural immobilized lipase. A time course study of its lipolytic activity in 1 L liquid broth revealed the maximum MBL activity at 4 h for mycelium cells harvested after 54 h. The yield and ...
Lu Xin-Hua XH Germplasm Repository of Pineapple (Ananas comosus) Zhanjiang City, Ministry of Agriculture, South Subtropical Crop Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang, Guangdong 524091, - - 2014
The fruit physico-chemical properties, antioxidant activity and mineral contents of 26 pineapple [Ananas comosus (L.) Merr.] genotypes grown in China were measured. The results showed great quantitative differences in the composition of these pineapple genotypes. Sucrose was the dominant sugar in all 26 genotypes, while citric acid was the principal ...
Nurdin Irwan I 0000-0002-1547-4810 Nanomaterials Engineering Research Group, Advanced Materials Research Laboratory, Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Department of Chemical Engineering, Lhokseumawe State Polytechnic, Lhokseumawe 24301, - - 2014
Maghemite (γ-Fe2O3) nanoparticles have been synthesized using a chemical coprecipitation method at different nitric acid concentrations as an oxidizing agent. Characterization of all samples performed by several techniques including X-ray diffraction (XRD), transmission electron microscopy (TEM), alternating gradient magnetometry (AGM), thermogravimetric analysis (TGA), dynamic light scattering (DLS), and zeta potential. ...
Lourith Nattaya N School of Cosmetic Science, Mae Fah Luang - - 2014
Para rubber seed was macerated in petroleum ether and n-hexane, individually, for 30 min. The extraction was additionally performed by reflux and soxhlet for 6 h with the same solvent and proportion. Soxhlet extraction by petroleum ether afforded the greatest extractive yield (22.90 ± 0.92%). Although antioxidant activity by means ...
Cheng Chin Jung CJ Department of Bioengineering, University of Washington, Seattle WA 98195-5013, USA. - - 2014
Bovine spongiform encephalopathy (BSE), or mad cow disease, is a fatal neurodegenerative disease that is transmissible to humans and that is currently incurable. BSE is caused by the prion protein (PrP), which adopts two conformers; PrPC is the native innocuous form, which is α-helix rich; and PrPSc is the β-sheet ...
Vadivelan Ganesan G Food Microbiology Department, Central Food Technological Research Institute, Mysore, Karnataka 570020, - - 2014
Mortierella sp. has been known to produce polyunsaturated fatty acids (PUFAs) such as GLA and AA under normal growth medium conditions. Similarly, under the stress condition, this fungus produces EPA and DHA in their mycelial biomass. Among the 67 soil samples screened from the Western Ghats of India, 11 Mortierella ...
Okazaki Fumiko F Kyoto Women's - - 2014
A direct competitive (dc)-ELISA was developed for rapid and simple determination of chlorothalonil residue in vegetables. A carboxylic acid derivative of pentachlorophenol was used to prepare an anti-chlorothalonil monoclonal antibody (MoAb) that showed adequate reactivity for dc-ELISA. Before homogenization of vegetable samples, phosphoric acid was added (vegetable-10% phosphoric acid (2 ...
Kale E - - 2014
The authors' objective was to measure amniotic fluid amino acid concentrations in pregnant women diagnosed as having fetuses with skeletal dysplasia in the second trimester of pregnancy. Eighteen pregnant women who had fetuses with with skeletal dysplasia detected by ultrasonography (skeletal dysplasia) in the second trimester and 35 women who ...
Rudnicki Witold R WR Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, Warsaw, - - 2014
That amino acid properties are responsible for the way protein molecules evolve is natural and is also reasonably well supported both by the structure of the genetic code and, to a large extent, by the experimental measures of the amino acid similarity. Nevertheless, there remains a significant gap between observed ...
Angermayr S Andreas SA Molecular Microbial Physiology Group, Swammerdam Institute for Life Sciences, University of Amsterdam and Netherlands Institute of Systems Biology, Science Park 904, 1098 XH Amsterdam, The - - 2014
Molecular engineering of the intermediary physiology of cyanobacteria has become important for the sustainable production of biofuels and commodity compounds from CO2 and sunlight by "designer microbes." The chemical commodity product L-lactic acid can be synthesized in one step from a key intermediary metabolite of these organisms, pyruvate, catalyzed by ...
Qian Yue-Cheng YC MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China. - - 2014
We report on the synthesis and application of a new hydrogel based on a methacrylate substituted polyphosphazene. Through ring-opening polymerization and nucleophilic substitution, poly[bis(methacrylate)phosphazene] (PBMAP) was successfully synthesized from hexachlorocyclotriphosphazene. By adding PBMAP to methacrylic acid solution and then treating with UV light, we could obtain a cross-linked polyphosphazene network, ...
Gundogdu Muttalip - - 2014
The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn ...
Saifullah Bullo B 0000-0002-0470-6292 Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology(ITMA), Universiti Putra Malaysia, 43400 Serdang, Selangor, - - 2014
Tuberculosis is a lethal epidemic, difficult to control disease, claiming thousands of lives every year. We have developed a nanodelivery formulation based on para-aminosalicylic acid (PAS) and zinc layered hydroxide using zinc nitrate salt as a precursor. The developed formulation has a fourfold higher efficacy of PAS against mycobacterium tuberculosis ...
Barahuie Farahnaz F Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra - - 2014
We characterize a novel nanocomposite that acts as an efficient anticancer agent. This nanocomposite consists of zinc layered hydroxide intercalated with protocatechuate (an anionic form of protocatechuic acid), that has been synthesized using a direct method with zinc oxide and protocatechuic acid as precursors. The resulting protocatechuic acid nanocomposite (PAN) ...
Weng Li-Chi LC 1] Graduate Institute of Marine Biotechnology, National Dong-Hwa University, Pingtung, 944 Taiwan - - 2014
The stability of cnidarian-dinoflagellate (genus Symbiodinium spp.) endosymbioses depends on the regulation of nutrient transport between Symbiodinium populations and their hosts. Previously, we successfully induced the production of lipid droplets in the free-living cultured Symbiodinium (clade B) under the nitrogen-deprivation condition for 5 days. Therefore, the present study aimed at ...
Zapała Lidia L Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, Rzeszow University of Technology, 6 Powstańców Warszawy Ave., 35-959 Rzeszow, - - 2014
The acid-base chemistry of three zwitterionic compounds, namely anthranilic (2-aminobenzoic acid), N-methylanthranilic and N-phenylanthranilic acid has been characterized in terms of the macroconstants K a1, K a2, the isoelectric point pH I, the tautomerization constant K z and microconstants k 11, k 12, k 21, k 22. The potentiometric titration ...
Mohadjerani Maryam M Department of Molecular and Cell Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, I. R. - - 2014
The objective of this study was to analyze the fatty acid content, antioxidant, and antibacterial activities of hydro-methanolic extract of Adonis wolgensis L. (A. wolgensis L.) growing wild in north of Iran. Oils of A. wolgensis L. was obtained by means of Soxhlet apparatus from leaves and stems. Methyl esters ...
Sun Kunlai K Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. - - 2014
Two new indole-diterpenoids (1 and 2) and a new isocoumarin (3), along with the known β-aflatrem (4), paspalinine (5), leporin B (6), α-cyclopiazonic acid (7), iso-α-cyclopiazonic acid (8), ditryptophenaline (9), aflatoxin B1 (10), 7-O-acetylkojic acid (11) and kojic acid (12), were isolated from the fermentation broth of the marine-derived fungus, ...
Jeevithan Elango E Department of Marine Pharmacology, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. - - 2014
Type II acid soluble collagen (CIIA), pepsin soluble collagen (CIIP) and type II gelatin (GII) were isolated from silvertip shark (Carcharhinus albimarginatus) cartilage and examined for their physicochemical and antioxidant properties. GII had a higher hydroxyproline content (173 mg/g) than the collagens and cartilage. CIIA, CIIP and GII were composed ...
Takahashi Tadanobu T Department of Biochemistry, School of Pharmaceutical Sciences, University of - - 2014
  Influenza A virus (IAV) has two envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). HA binds to sialic acids at the terminals of glycochains on the host cell surface as virus receptors. NA shows sialidase activity, which cleaves sialic acids from the terminals of glycochains. A new subtype (antigenicities of HA ...
Chen Yong Y Department of Life Sciences, Hunan Institute of Humanities, Science and Technology, Loudi 417000, - - 2014
The present study is to explore the optimal extraction parameters, antioxidant activity, and antimicrobial activity of alkaline soluble polysaccharides from rhizome of Polygonatum odoratum. The optimal extraction parameters were determined as the following: NaOH concentration (A) 0.3 M, temperature (B) 80°C, ratio of NaOH to solid (C) 10-fold, and extraction time ...
Poehlein Anja A Genomic and Applied Microbiology and Göttingen Genomics Laboratory, Georg-August University, Göttingen, - - 2014
Clostridium litorale is a Gram-positive, rod-shaped, and spore-forming bacterium, which is able to use amino acids such as glycine, sarcosine, proline, and betaine as single carbon and energy sources via Stickland reactions. The genome consists of a circular chromosome (3.41 Mb) and a circular plasmid (27 kb).
Chandel Anuj K AK Department of Biotechnology, School of Engineering of Lorena, Estrada Municipal do Campinho, University of São Paulo, Caixa Postal 116 12.602.810, Lorena, São Paulo, - - 2014
Heavy usage of gasoline, burgeoning fuel prices, and environmental issues have paved the way for the exploration of cellulosic ethanol. Cellulosic ethanol production technologies are emerging and require continued technological advancements. One of the most challenging issues is the pretreatment of lignocellulosic biomass for the desired sugars yields after enzymatic ...
Uraji Misugi M Research Institute for Biological Sciences (RIBS), Okayama Prefectural Technology Center for Agriculture, Forestry, and Fisheries, Kaga-gun, Okayama, - - 2014
Ferulic acid (FA), a component of hemicellulose in plant cell walls, is a phenolic acid with several potential applications based on its antioxidant properties. Recent studies have shown that feruloyl esterase (FAE) is a key bacterial enzyme involved in FA production from agricultural biomass. In this study, we screened a ...
Zhang Lizhen L College of Life Science, Shanxi University, Taiyuan, - - 2014
The phytochemical content, antioxidant activity and antiproliferative properties of three diverse varieties of proso millet are reported. The free phenolic content ranged from 27.48 (Gumi 20) to 151.14 (Mi2504-6) mg gallic acid equiv/100 g DW. The bound phenolic content ranged from 55.95 (Gumi20) to 305.81 (Mi2504-6) mg gallic acid equiv/100 ...
Walker Valerie V 0000-0003-3921-3073 Department of Clinical Biochemistry, Southampton General Hospital, C level, MP 6, South Block, Tremona Road, Southampton SO16 6YD, - - 2014
Production of 2-pentanone, a methylketone, is increased in fasting ketotic humans. Its origin is unknown. We hypothesised that it is formed via β -oxidation of hexanoic acid by the peroxisomal pathway proposed for methylketone-producing fungi and yeasts. We used Penicillium roqueforti cultured on fat (margarine) to investigate 2-pentanone production. Headspace ...
Kiyota Hiroshi H Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. - - 2014
Nutrient balance is important for photosynthetic growth and biomass production in microalgae. Here, we investigated and compared metabolic responses of amino acid pools to nitrogen and sulfur starvation in a unicellular model cyanobacterium, Synechocystis sp. PCC 6803, and its mutant nblA1/A2. It is known that NblA1/A2-dependent and -independent breakdown of ...
Nakayama Hirokazu H Department of Functional Molecular Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan. - - 2014
The immobilization of potassium sorbate, potassium aspartate and sorbic acid in layered double hydroxide under solid condition was examined. By simply mixing two solids, immobilization of sorbate and aspartate in the interlayer space of nitrate-type layered double hydroxide, so called intercalation reaction, was achieved, and the uptakes, that is, the ...
Ylitervo Päivi P Swedish Centre for Resource Recovery, University of Borås, 501 90 Borås, Sweden. - - 2014
The release of inhibitory concentrations of acetic acid from lignocellulosic raw materials during hydrolysis is one of the main concerns for 2nd generation ethanol production. The undissociated form of acetic acid can enter the cell by diffusion through the plasma membrane and trigger several toxic effects, such as uncoupling and ...
Kabeya Naoki N Research Fellow of the Japan Society for the Promotion of Science, 1-8 Ichiban-cho, Chiyoda-ku, Tokyo 102-8472, Japan; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, Tokyo 108-8477, - - 2013
Marine fishes are generally unable to produce sufficient quantities of eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) for their normal growth and survival, as the key fatty acid-metabolizing enzymes in the EPA and DHA biosynthetic pathway are limited. It is therefore necessary to supplement cultured marine fish species ...
Smet Lieselotte De LD Laboratory of Pharmaceutical Technology, Ghent University, Ghent, - - 2013
The aim of the study was to increase the bioavailability of itraconazole (ITRA) using nanosized cocrystals prepared via wet milling of ITRA in combination with dicarboxylic acids. Wet milling was used in order to create a nanosuspension of ITRA in combination with dicarboxylic acids. After spray-drying and bead layering, solid ...
Hamberg Mats M Karolinska Institutet, - - 2013
The CYP74 family of cytochrome P450 enzymes consisting of allene oxide synthase, divinyl ether synthase and hemiacetal synthase has important roles in plant oxylipin biosynthesis, transforming lipoxygenase-generated fatty acid hydroperoxides into a range of biologically active compounds. Biochemical and phylogenetic studies have shown that CYP74-related enzymes are found also in ...
Stoffel Wilhelm W Center of Molecular Medicine (CMMC) Laboratory of Molecular Neurosciences, Institute of Biochemistry University of Cologne, Cologne, - - 2013
Δ-6-fatty acid desaturase (FADS2) is the key enzyme in the biosynthesis of polyunsaturated fatty acids (PUFAs), the essential structural determinants of mammalian membrane lipid-bilayers. We developed the auxotrophic fads2(-/-) mouse mutant to assess the enigmatic role of ω3- and ω6-PUFAs in lipid homeostasis, membrane structure and function. Obesity resistance is ...
Oldham C L CL Department of Plant and Wildlife Sciences, Brigham, Young University, Provo, UT, - - 2013
The purpose of this study was to determine the diurnal composition and concentration of volatile fatty acids (VFA) and to determine VFA composition and concentration differences between stomach compartment 1 (C1) and caecum of alpacas fed grass and alfalfa hay. The study was divided into two experiments. In Experiment 1 ...
Ahsan Laboni L Limerick Pulp and Paper Centre and Department of Chemical Engineering, University of New Brunswick, Fredericton, New Brunswick E3B 5A3, Canada. Electronic address: - - 2013
This work investigated the feasibility of recovering and concentrating sugars and acetic acid (HAc) from prehydrolysis liquor (PHL) of the kraft-based dissolving pulp process prior to fermentation of hemicellulosic sugars, by the combination of activated carbon adsorption, nanofiltration (NF) and reverse osmosis (RO) processes. To reduce the fouling PHL was ...
Mostefaoui Houda H Zoophytiatrie Laboratory, Department of Agronomy, Faculty of Agricultural Sciences and Veterinary, University Saad Dahleb, 9000 Blida, - - 2014
Aphis spiraecola and Aphis gossypii cause harmful damages on clementine tree orchards. Weekly surveys measured the abundance of aphids (larvae, winged and wingless adults) as well as of auxiliary insects and parameters of energy metabolism. Correlatively, soluble carbohydrates, total free amino acids, free proline and condensed tannins were quantified in ...
Urbaniak Michael D MD Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, - - 2013
The zinc-metalloenzyme GlcNAc-PI de-N-acetylase is essential for the biosynthesis of mature GPI anchors and has been genetically validated in the bloodstream form of Trypanosoma brucei, which causes African sleeping sickness. We screened a focused library of zinc-binding fragments and identified salicylic hydroxamic acid as a GlcNAc-PI de-N-acetylase inhibitor with high ...
Motter Francine A FA Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, Cx. P. 19046 Centro Politécnico, Curitiba 81531-980, Paraná, Brazil; VTT Technical Research Centre of Finland, Tietotie 2, Espoo, P.O. Box 1500, 02044 VTT, - - 2013
In the genome of Aspergillus niger five genes were identified coding for proteins with homologies to sugar acid dehydratases. The open reading frames were expressed in Saccharomyces cerevisiae and the activities tested with a library of sugar acids. Four genes were identified to code for proteins with activities with sugar ...
Modirroosta Bentol Hoda BH Department of Agronomy and Plant Breeding, Faculty of Agriculture, University of Zanjan, Zanjan, Islamic Republic of - - 2013
Compositional studies comparing transgenic with non-transgenic counterpart plants are almost universally required by governmental regulatory bodies. In the present study, two T2 transgenic cotton lines containing chitinase (Line 11/57) and Bt lines (Line 61) were compared with non-transgenic counterpart. To do this, biochemical characteristics of leaves and seeds, including amino ...
Wendlinger Christine C University of Hohenheim, Institute of Food Chemistry (170 b), Garbenstraße 28, D-70593 Stuttgart, - - 2014
Erucic acid is a typical constituent of mustard or rape. Foodstuff with a high content of erucic acid is considered undesirable for human consumption because it has been linked to myocardial lipidosis and heart lesions in laboratory rats. As a result, several countries have restricted its presence in oils and ...
Broadbent J R JR Department of Nutrition, Dietetics, and Food Science, Utah State University, 8700 Old Main Hill, Logan, UT, 84322-8700, USA, - - 2013
Lactic acid is an important industrial chemical commonly produced through microbial fermentation. The efficiency of acid extraction is increased at or below the acid's pKa (pH 3.86), so there is interest in factors that allow for a reduced fermentation pH. We explored the role of cyclopropane synthase (Cfa) and polysorbate ...
Wolf Cynthia J CJ Developmental Toxicology Branch, Toxicity Assessment Division, National Health and Environmental Effects Research Laboratory, ORD, U.S. EPA Research Triangle Park, NC 27711. Electronic address: - - 2013
Perfluoroalkyl acids (PFAAs) are found globally in the environment, detected in humans and wildlife, and are typically present as mixtures of PFAA congeners. Mechanistic studies have found that responses to PFAAs are mediated in part by PPARα. Our previous studies showed that individual PFAAs activate PPARα transfected into COS-1 cells. ...
Kim Hyoung-Jun HJ Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Wonju, Gangwon-do 220-710, Republic of - - 2013
We have successfully prepared nanohybrids of biofunctional ferulic acid and layered double hydroxide nanomaterials through reconstruction and exfoliation-reassembly routes. From X-ray diffraction and infrared spectroscopy, both nanohybrids were determined to incorporate ferulic acid molecules in anionic form. Micrsocopic results showed that the nanohybrids had average particle size of 150 nm with ...
Sato Eisuke E School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan. Electronic address: - - 2013
BPA used in BNCT has a similar structure to some essential amino acids and is transported into tumor cells by amino acid transport systems. Previous study groups have tried various techniques of loading BPA to increase intracellular boron concentration. CHO-K1 cells demonstrate system L (LAT1) activity and are suitable for ...
Zhang Yongming Y Department of Environmental Science and Engineering, College of Life and Environmental Science, Shanghai Normal University , Shanghai, 200234, People's Republic of - - 2013
Pyridine, a nitrogen-containing heterocyclic compound, is slowly biodegradable, and coupling biodegradation with UV photolysis is a potential means to accelerate its biotransformation and mineralization. The initial steps of pyridine biodegradation involve mono-oxygenation reactions that have molecular oxygen and an intracellular electron carrier as cosubstrates. We employed an internal circulation baffled ...
Shou Qingyao Q Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore NSW 2480, Australia. Electronic address: - - 2013
Five anthranilic acid derivatives, a mixture I of three new compounds 11'-hexadecenoylanthranilic acid (1), 9'-hexadecenoylanthranilic acid (2), and 7'-hexadecenoylanthranilic acid (3), as well as a new compound 9,12,15-octadecatrienoylanthranilic acid (4) together with a new natural product, hexadecanoylanthranilic acid (5), were isolated from Geijera parviflora Lindl. (Rutaceae). Their structures were elucidated ...
Price Daniel R G DR Department of Biology, University of Miami, Coral Gables, FL - - 2014
Endosymbiotic associations have played a major role in evolution. However, the molecular basis for the biochemical interdependence of these associations remains poorly understood. The aphid-Buchnera endosymbiosis provides a powerful system to elucidate how these symbioses are regulated. In aphids, the supply of essential amino acids depends on an ancient nutritional ...
Park Ji-Yeon JY Department of Clean Fuel, Korea Institute of Energy Research, Daejeon 305-343, Republic of Korea. Electronic address: - - 2013
Acid-catalyzed hot-water treatment for efficient extraction of lipids from a wet microalga, Chlorella vulgaris, was investigated. For an initial fatty acids content of 381.6mg/g cell, the extracted-lipid yield with no heating and no catalyst was 83.2mg/g cell. Under a 1% H2SO4 concentration heated at 120°C for 60min, however, the lipid-extraction ...
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