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Woldegiorgis Ashagrie Z AZ Center for Food Science and Nutrition, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia. Electronic address: - - 2014
Two cultivated (P. ostreatus and L. edodes) and five wild (L. sulphureus, A. campestris, T. clypeatus, T. microcarpus and T. letestui) edible mushrooms were analyzed for their antioxidant activities, total phenolics, total flavonoids, phenolic profile and ergothioneine content. Results showed that A. campestris had the greatest antioxidant activity in all ...
Paudel Liladhar L School of Chemistry, University of Manchester , Oxford Road, Manchester M13 9PL, United - - 2014
Black raspberry ( Rubus occidentalis L.) (BR) fruit extracts with differing compound profiles have shown variable antiproliferative activities against HT-29 colon cancer cell lines. This study used partial least-squares (PLS) regression analysis to develop a high-resolution (1)H NMR-based multivariate statistical model for discerning the biological activity of BR constituents. This ...
Menegazzo Mariana Lara ML Laboratory of Bioengineering, Faculty of Engineering, Federal University of Grande Dourados, Dourados, MS, - - 2014
In this study, crude oil was extracted by heating and filtering of the residual fat obtained from the processing of mechanically separated meats of Nile tilapia (Oreochromis niloticus) and hybrid sorubim (Pseudoplatystoma corruscans×P. fasciatum) for protein concentrate obtaining. The crude oil was refined by the following steps: degumming with 85% ...
Shobharani P P Department of Food - - 2014
The current investigation was carried out with an objective of determining the structural characteristic of polysaccharides extracted from fermented Sargassum sp. to be used as potent natural heparin substitute anticoagulant compound. Sargassum sp. fermented with marine lactic acid bacteria was initially subjected to ethanol precipitation for the recovery of bioactive ...
Gong Ting T a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100050 , - - 2014
Microbial transformation of the oleanolic acid (1) using Trichothecium roseum (pers.) Link (M 95.56) has resulted in the isolation of two new hydroxylated type metabolites, characterized as 15α-hydroxy-3-oxo-olean-12-en-28-oic acid (2) and 7β,15α-dihydroxy-3-oxo-olean-12-en-28-oic acid (3). The structure elucidation of these metabolites was based primarily on HR-EIMS, 1D NMR, and 2D NMR ...
Neely Jamie M JM Department of Chemistry, Colorado State University , Fort Collins, Colorado 80523, United - - 2014
α,β-Unsaturated carboxylic acids undergo Rh(III)-catalyzed decarboxylative coupling with α,β-unsaturated O-pivaloyl oximes to provide substituted pyridines in good yield. The carboxylic acid, which is removed by decarboxylation, serves as a traceless activating group, giving 5-substituted pyridines with very high levels of regioselectivity. Mechanistic studies rule out a picolinic acid intermediate, and ...
Guo Fajin F CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR - - 2014
Both filamentous microalgae Tribonema and unicellular microalgae Nanochloropsis are promising feedstock for biodiesel production. Nitrogen starvation increased lipid content in Nannochloropsis but decreased that in Tribonema. In this study, biochemical responses of Tribonema under different levels of nitrogen (0N, 0.05N, 0.1N and 1N-BG11) were investigated. 1N-BG11 was sufficient during 15-day-cultivation, ...
Glad Trine T Department of Arctic and Marine Biology, UiT The Arctic University of Norway, 9037, Tromsø, - - 2014
Reindeer (Rangifer tarandus tarandus) may include large proportions of lichens in their winter diet. These dietary lichens are rich in phenolic secondary compounds, the most well-known being the antimicrobial usnic acid. Previous studies have shown that reindeer host rumen bacteria resistant to usnic acid and that usnic acid is quickly ...
Khan Asma Yasmeen AY Biophysical Chemistry Laboratory, Chemistry Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700 032, - - 2014
The interaction of phenazinium dyes, safranine O and phenosafranine with single stranded polyadenylic acid was studied using spectroscopic viscometric and calorimetric techniques. Both dyes bind to polyadenylic acid strongly with association constant of the order of 10(5)M(-1). Safranine O showed higher affinity over phenosafranine. The binding induced conformational changes in ...
Frommeyer Maja M Institut für Molekulare Mikrobiologie und - - 2014
Soluble cyanobacterial granule polypeptide (CGP), especially isolated from recombinant Escherichia coli strains, consists of aspartic acid, arginine and an increased amount of lysine in contrast to insoluble CGP isolated from cyanobacteria or various other recombinant bacteria. In vitro guanidination of lysine side chains of soluble CGP with o-methylisourea (OMIU) yielded ...
Miladinović Bojana B Faculty of Medicine, Dept. of Pharmacy, Univ. of Niš, Blvd Dr Zoran Đinđić 81, 18000, Niš, - - 2014
The aim of this article was to determine the chemical composition (anthocyanin and ascorbic acid contents, total phenols, and tannins), and the antioxidative, and antimicrobial activities of the juices and methanol extracts of 4 varieties-Tenah, Triton, Ben Sarek, and Ometa. The juices were made during 2008, 2009, and 2010 from ...
Lueth Christopher A CA Sandia National Laboratories, Albuquerque, New Mexico 87185, - - 2014
We perform atomistic molecular dynamics simulations of melts of four precise acid copolymers, two poly(ethylene-co-acrylic acid) (PEAA) copolymers, and two poly(ethylene-co-sulfonic acid) (PESA) copolymers. The acid groups are spaced by either 9 or 21 carbons along the polymer backbones. Hydrogen bonding causes the acid groups to form aggregates. These aggregates ...
Yang Xiao-Yan XY Key Laboratory of Renewable Energy, Chinese Academy of Sciences, Guangzhou, 510640 People's Republic of China ; Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, No. 2 Nengyuan Road, Tianhe District, Guangzhou, 510640 People's Republic of China ; University of Chinese Academy of Sciences, Beijing, 100049 People's Republic of - - 2014
In this work, acetic acid was found as one promising substrate to improve xylose utilization by Gluconacetobacter xylinus CH001. Also, with the help of adding acetic acid into medium, the bacterial cellulose (BC) production by G. xylinus was increased significantly. In the medium containing 3 g l(-1) acetic acid, the optimal xylose ...
Wilkins Stewart - - 2014
In-situ functionalization of polar (c-plane) and nonpolar (a-plane) gallium nitride (GaN) was performed by adding (3-bromopropyl)bromopropyl) phosphonic acid or propyl phosphonic acid to a phosphoric acid etch. The target was to modulate GaN's emission properties and oxide formation, which was explored through surface characterization with atomic force microscopy (AFM), x-ray ...
Ostash Bohdan B Department of Genetics and Biotechnology, Ivan Franko National University, Lviv, 4 Hrushevskoho st, Lviv, 79005, - - 2014
The cell wall of the model actinomycete Streptomyces coelicolor M145 has recently been shown to contain the novel glycopolymer teichulosonic acid. The major building block of this polymer is 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (Kdn), suggesting initial clues about the genetic control of biosynthesis of this cell wall component. Here, through genome mining ...
Venditti A A a Dipartimento di Chimica , Università di Roma "La Sapienza" , Piazzale Aldo Moro 5, 00185 Roma , - - 2014
In this study, the iridoidic content of two accessions of Crucianella maritima L., one from Sardinia and the second from Latium, was examined and compared. From a qualitative point of view, the iridoidic pattern of the two samples was similar, since the same compounds (asperuloside, asperulosidic acid and deacetyl asperulosidic ...
Panagos Charalampos G CG EaStCHEM School of Chemistry, Joseph Black Building, The King's Buildings, Edinburgh EH9 3JJ, UK. Electronic address: - - 2014
The lumpsucker, Cyclopterus lumpus, a cottoid teleost fish found in the cold waters of the North Atlantic, and North Pacific, was identified as a possible source of GAGs. The GAGs present in the C. lumpus dorsal hump and body wall tissue were isolated and purified. Two fractions were analysed by ...
Jie Weiguang W State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China; Department of Food and Environment Engineering, East University of Heilongjiang, Harbin 150086, - - 2014
This study aimed at exploring a new approach for producing volatile fatty acids (VFAs) from excess sludge (ES). Two representative alkali-tolerant bacteria (HIT-01 and HIT-02) were isolated from ES, and inoculated separately or jointly into ES to investigate their effects on VFAs accumulation, soluble organic compounds concentrations, and bacterial community ...
Tanaka Keijitsu K Tsukuba Research and Technology Center, SDS Biotech K.K., Midorigahara, Tsukuba, Ibaraki 300-2646, - - 2014
Two new cyclic lipopeptides (3 and 4) were isolated from the culture filtrate of Bacillus amyloliquefaciens strain SD-32, together with two known metabolites, iso-C15 and iso-C16 bacillomycin D (1 and 2). Spectroscopic and chemical analyses identified the structures of the new compounds 3 and 4 as anteiso-C17 bacillomycin D, cyclic ...
Lim Chaemin C College of Pharmacy, Seoul National University , 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, - - 2014
CD1d molecules recognize glycolipid antigens with straight chain fatty acid moieties. Although most of the residues in the CD1d binding groove are hydrophobic, some of the amino acids can form hydrogen bonds. Consequently, we have designed ω-hydroxy fatty acid-containing glycolipid derivatives of the prototypical CD1d ligand α-GalCer. The potency of ...
Kimura Koji K Department of Chemistry, Faculty of Liberal Arts and Education, Shiga - - 2014
The neutral glycosphingolipids, mono-, di-, tri- and tetraglycosylceramides (GL-1, GL-2, GL-3, GL-4a and GL-4b), were identified from whole tissues of the marine crab Erimacrus isenbeckii by successive column chromatography with ion exchange Sephadex (QAE-Sephadex), magnesium silicate (Florisil) and silicic acid (Iatrobeads) resins. Through component analysis, sugar analysis, methylation studies, exoglycosidase ...
Viktorova Ekaterina G EG Department of Veterinary Medicine, University of Maryland, College Park, - - 2014
Genome replication of positive strand RNA viruses of eukaryotes is universally associated with specialized membranous structures referred to as replication organelles. Accumulating evidence show that new membrane synthesis is important for the development of the replication organelles of diverse picornaviruses and likely for other positive strand RNA viruses as well. ...
Huang Haofei H College of Chemical Engineering, Shandong University of Technology, Zibo 255049 (P.R. China); Department of Chemistry and Nanosciences, Ewha Womans University, Daehyun-dong 11-1, Seoul 120-750 (Korea), Fax: - - 2014
The hydroxyphenyl chiral ketone, (S)-3, reacts with D-amino acids bearing hydrophobic side chains exclusively over the L-amino acids in a two-phase liquid-liquid extraction, and thus acts as a highly stereoselective extractant. Calculations for the energy-minimized structures for the imine diastereomers and the comparison of the selectivities with other phenyl ketones, ...
Gu Hanqi H State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, - - 2014
Industrial waste corncob residues (CCR) are rich in cellulose and can be hydrolyzed directly without pretreatment. However, a poor fermentation performance was frequently observed in the simultaneous saccharification and ethanol fermentation (SSF) of CCR, although the furans and organic acid inhibitors were very low. In this study, the high level ...
Youn Kumju K 1 Department of Food Science and Nutrition, Dong-A University , Saha-gu, Busan, - - 2014
Abstract In our ongoing research to find therapeutic compounds for Alzheimer's disease (AD) from natural resources, the inhibitory activity of the BACE1 enzyme by Tenebrio molitor larvae and its major compounds were evaluated. The T. molitor larvae extract and its fractions exhibited strong BACE1 suppression. The major components of hexane ...
Grecco Simone dos S Sdos - - 2014
Bioassay-guided fractionation of the EtOH extract of the aerial parts of Baccharis uncinella C. DC. (Asteraceae) led to identification of two cinnamic acid derivatives (caffeic and ferulic acids), two flavones (hispidulin and pectolinaringenin) and a mixture of three chlorogenic acids (3,4-, 3,5- and 4,5-O-dicaffeoylquinic acids), which displayed in vitro anti-trypanosomal ...
Petreus Tudor T Gr.T.Popa University of Medicine and Pharmacy Iasi, 16 Universitatii Str., 700115, Iasi, Romania, - - 2014
Chemical modification of cellulose by phosphorylation enhances its bioactivity and provides new derivatives and materials with specific end uses. In the present study, cellulose derivatized with phosphorous acid was obtained using the reaction of microcrystalline cellulose with phosphorous acid-urea mixture, in molten state, in comparison with others methods that used ...
Platero Ana Isabel AI Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide/Consejo Superior de Investigaciones Científicas/Junta de Andalucía, and Departamento de Biología Molecular e Ingeniería Bioquímica, Universidad Pablo de - - 2014
The Pseudomonas sp. ADP plasmid pADP-1 encodes the activities involved in the hydrolytic degradation of the s-triazine herbicide atrazine. Here we explore the presence of a specific transport system for the central intermediate of the atrazine utilization pathway, cyanuric acid, in Pseudomonas sp. ADP. Growth in fed-batch cultures containing limiting ...
Singh Pradeep Pratap PP a Bio-Organic Laboratory, Department of Chemistry , University of Delhi , Delhi 110007 , - - 2014
An activity-guided isolation and purification process was used to identify the l,l-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging components of the food plant (Terminalia arjuna) of Antheraea mylitta. Dry leaves of T. arjuna were extracted with different solvents and tested for their antioxidant activity against DPPH(•). The acetone-water (8:2) extract expressed strong DPPH ...
Filannino P P Department of Soil, Plant and Food Science, University of Bari Aldo Moro, I-70126 Bari - - 2014
Strains of Lactobacillus plantarum were grown and stored in cherry (ChJ), pineapple (PJ), carrot (CJ) and tomato (TJ) juices to mimic the chemical composition of the respective matrices. Wheat flour hydrolysate (WFH), whey milk (W), and MRS broth were also used as representative of other ecosystems. The growth rate and ...
Bhat Rajeev R Food Technology Division, School of Industrial Technology, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia. Electronic address: - - 2014
Belinjau (Gnetum gnemon L.) seed flour was evaluated for nutritional composition, antioxidant activity and functional properties. Seed flour was found to be rich in protein (19.0g/100g), crude fibre (8.66g/100g), carbohydrates (64.1%), total dietary fibre (14.5%) and encompassed adequate amounts of essential amino acids, fatty acids and minerals. Antioxidant compounds such ...
Lim Ze Long ZL Bioriginal Food and Science Corporation, Saskatoon, SK, S7N 0W9, - - 2014
Although ω3- and ω6- desaturases have been well studied in terms of substrate preference and regiospecificity, relatively little is known about the membrane-bound, "front-end" long chain fatty acid desaturases, such as ∆4, Δ5 or Δ6 desaturases. The first vertebrate ∆4 desaturase was recently identified in the marine teleost fish Siganus ...
Santos Nathalia O NO Department of Biochemical Engineering, School of Chemistry, Federal University of Rio de Janeiro, Cidade Universitária, Centro de Tecnologia, Bl. E, Sl. 203, Ilha do Fundão, 21941-909 Rio de Janeiro, - - 2014
Methane production from marine microalgae Isochrysis galbana was assessed before and after mechanical and chemical pretreatments. Mechanical pretreatment resulted in a 61.7% increase in soluble Chemical Oxygen Demand. Different hydrolysis conditions were evaluated by varying temperature - T, sulfuric acid concentration - AC and biomass suspension concentration (measured as particulate ...
Ji Min-Kyu MK Department of Environmental Engineering, Yonsei University, Wonju 220-710, South - - 2014
Effect of mine wastewater on the nutrient removal efficiency of a green microalga Micratinium reisseri from concentrated municipal wastewater (CMW) with simultaneous lipid production was investigated. Different dilution ratios (1-10%) of CMW either with mine wastewater (MWF) or mine wastewater without Fe (MWOF) were used. M. reisseri showed the highest ...
Souza Karla Silva Teixeira - - 2014
In this study, crude glycerol was used as carbon source in the cultivation of wild yeasts aiming to the production of microbial lipids and citric acid. Forty yeasts of different sources were tested concerning their growth in crude and commercial glycerol. Four yeasts (Lidnera saturnus UFLA CES-Y677, Yarrowia lipolytica UFLA ...
Morita Yuya Y Department of Chemical Systems Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7300 - - 2014
Layered niobium molybdate (HNbMoO6 ) was used in the aqueous-phase dehydration of sorbitol and was found to exhibit remarkable selectivity toward its monomolecular-dehydrated intermediate 1,4-sorbitan. This was attributed to the selective intercalation of sorbitol within the interlayers with strong Brønsted acid sites.
Maindad D V DV Institute of Bioinformatics and Biotechnology, University of Pune, Pune, 411007 - - 2014
Acinetobacter calcoaceticus HIRFA32 from wheat rhizosphere produced catecholate type of siderophore with optimum siderophore (ca. 92 % siderophore units) in succinic acid medium without FeSO4 at 28 °C and 24 h of incubation. HPLC purified siderophore appeared as pale yellow crystals with molecular weight [M(+1)] m/z 347.18 estimated by LCMS. The structure elucidated ...
Soni Jigar N JN Department of Chemistry, Faculty of Science, The M.S. University of Baroda, Vadodara 390002, - - 2014
We have synthesized various amide derivatives of benzodifuran-2-carboxylic acid from resorcinol. Reaction of 7-hydroxy-4-methylcoumarin with chloroacetone in anhydrous K2CO3 and dry acetone gave ether derivative of 7-hydroxy-4-methylcoumarin 3 which on reaction with N-bromosuccinimide in chloroform gave corresponding 3-bromo derivative 4. Cyclization of bromo derivative in 10% ethanolic KOH gave benzodifuran-2-carboxylic ...
Zhang Xiaomin X 1] State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China [2] University of Chinese Academy of Sciences, Beijing 100049, - - 2014
Tightening environmental legislation is driving the chemical industries to develop efficient solid acid catalysts to replace conventional mineral acids. Polystyrene sulphonic acid resins, as some of the most important solid acid catalysts, have been widely studied. However, the influence of the morphology on their acid strength-closely related to the catalytic ...
Zhong Yin Y State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Wushan, Guangzhou 510640, - - 2014
Hydrometallurgy is an acid leaching based process widely used for recovering precious metals from electronic wastes (e-wastes). The effects of acid leaching on the fate of brominated flame retardants (BFRs) in typical hydrometallurgical processes remain largely unknown. This study was aimed at evaluating the fate of tetrabromobisphenol A (TBBPA), a ...
Bornø Andreas A Clinical Metabolomics Core Facility (CMCF), Rigshospitalet, Section 7652, Ole Maaløesvej 26, 2100 Copenhagen, Denmark. Electronic address: - - 2014
An important area within clinical functional metabolomics is in vivo amino acid metabolism and protein turnover measurements for which accurate amino acid concentrations and stable isotopically labeled amino acid enrichments are mandatory not the least when tissue metabolomics is determined. The present study describes a new sensitive liquid chromatography tandem ...
Coello Laura L Medicinal Chemistry Department, PharmaMar S. A., Pol. Ind. La Mina Norte , Avenida de los Reyes 1, 28770, Colmenar Viejo (Madrid), - - 2014
Two new cyclic depsipeptides, pipecolidepsins A and B (1 and 2), have been isolated from the sponge Homophymia lamellosa collected off the coast of Madagascar. Their structures were determined by a combination of NMR experiments and by LC-MS analysis of the amino acid fragments obtained by hydrolysis and derivatization using ...
Szostak Michal M School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK. michal.szostak@manchester.ac.uk - - 2014
Structural characterisation and reactivity of new tetrahedral intermediates based on a highly modular barbituric acid scaffold, formed via chemoselective electron transfer using the SmI2-H2O reagent, are reported. Lewis acid promoted cleavage of bicyclic α-amino alcohols affords vinylogous N-acyliminium ions, which undergo selective (>95 : 5, 1,4 over 1,2) capture with a suite ...
Yildiz Fitnat F Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of - - 2014
The ability to form biofilms is important for environmental survival, transmission, and infectivity of Vibrio cholerae, the causative agent of cholera in humans. To form biofilms, V. cholerae produces an extracellular matrix composed of proteins, nucleic acids and a glycoconjugate, termed Vibrio exopolysaccharide (VPS). Here, we present the data on ...
Filatov Andrei V AV N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, - - 2014
On mild acid degradation of the lipopolysaccharide of Enterobacter cloacae C6285, the O-polysaccharide was cleaved at residues of 5,7-diacetamido-3,5,7,9-tetradeoxy-d-glycero-d-galacto-non-2-ulosonic acid (di-N-acetyllegionaminic acid, Leg5Ac7Ac) in the main chain. The resultant oligosaccharide and an alkali-treated lipopolysaccharide were studied by sugar analysis along with (1)H and (13)C NMR spectroscopy, and the following structure ...
Sato Renata Takabayashi RT Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Juiz de Fora, Cidade Universitária CEP, 36036-330, Juiz de Fora, MG, - - 2014
Olive oil is a very important product to human health since it inhibits formation of free radicals, tumour growth, lesions and inflammatory substances. High concentrations of free fatty acids in olive oils results in lipid deterioration due to oxidative or hydrolytic rancidity. To optimise an alternative capillary zone electrophoresis methodology, ...
Lai Mei-Chun MC Department of Chemistry, Center for Nanotechnology and Center for Biomedical Technology at Chung-Yuan Christian University, Chung Li, Taiwan 32023, Republic of - - 2014
Thermosensitive hydrogels are renowned carriers that are used to deliver a variety of drugs with the aim of combating diseases. In this study, the injectability of thermosensitive hydrogels comprised of poly(ethylene glycol)-poly(lactic acid-co-glycolic acid)-poly(ethylene glycol) (PEG-PLGA-PEG, PELGE) and hydroxyapatite (HA) were examined for their ability to deliver bone morphological protein ...
Tareq Fakir Shahidullah FS Department of Marine Biotechnology, University of Science and Technology , Republic of - - 2014
Gageotetrins A-C (1-3), a unique class of linear lipopeptides, consisting of di- and tetrapeptides and a new fatty acid were isolated from a Marine Bacillus subtilis. The structures of 1-3 were assigned by spectroscopic data and their absolute stereochemistries were ascertained by chemical derivatization. Compounds 1-3 displayed good antimicrobial activities ...
Kaise Hiromi H Graduate School of Pharmaceutical Sciences, University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, - - 2014
Redox transformation of an α,β-unsaturated aldehyde to a carboxylic acid derivative by means of a combination of TMSCN and DBU was investigated. In addition to the wide use of the carboxylic acid derivatives provided by this reaction, temperature-dependent control of the kinetic or thermodynamic protonation pattern was found to selectively ...
He Jie - - 2014
Monodisperse porous zirconia (ZrO2) microspheres with nanocrystallized framework were fabricated by impregnation of porous polymer microspheres as a novel hard template with zirconia precursors followed by calcination to remove the template. Porous phosphorylated zirconia (PhZr) microspheres were prepared by further treating porous zirconia microspheres with phosphoric acid. The morphology, structure, ...
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