Search Results
Results 151 - 200 of 2351
1 2 3 4 5 6 7 8 9 10 >
Zhong Yan - - 2011
A novel codrug (LMX) was obtained from lamivudine (LMV) and ursolic acid (UA) coupled with ethyl chloroacetate through an amide and ester linkage. The structure of LMX was confirmed by (1)H NMR, (13)C NMR, IR and HRMS. Herein, the in vitro non-enzymatic and enzymatic hydrolysis and in vivo pharmacological activities ...
Zhang Bin W BW Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, - - 2011
HdeA protein is a small, ATP-independent, acid stress chaperone that undergoes a dimer-to-monomer transition in acidic environments. The HdeA monomer binds a broad range of proteins to prevent their acid-induced aggregation. To understand better HdeA's function and mechanism, we perform constant-pH molecular dynamics simulations (CPHMD) to elucidate the details of ...
Hossain Muhammed Anwar - - 2012
The objective of this study was to investigate the effect of vehicle systems, pH and enhancers on the permeation of a highly lipophilic basic drug aripiprazole (ARPZ) through human cadaver skin. Solubility of ARPZ in single, binary, tertiary, and quaternary vehicle systems of N-methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO), water, ...
Li Guan - - 2011
Stevia, as animal feed additive, has been researched into over the years, but how to rapidly predict its amino acids contents is yet to be studied. In the present study, 301 samples of stevia leaf powder were defined as the calibration set from which calibration models were optimized and the ...
Wang Qingzhao - - 2011
Lactic acid, an attractive, renewable chemical for production of biobased plastics (polylactic acid, PLA), is currently commercially produced from food-based sources of sugar. Pure optical isomers of lactate needed for PLA are typically produced by microbial fermentation of sugars at temperatures below 40 °C. Bacillus coagulans produces L(+)-lactate as a primary ...
Liu Jun - - 2011
Urea in alcoholic beverages is a precursor of ethyl carbamate, which is carcinogenic. Acid urease (EC 3.5.1.5) is regarded as a good approach to scavenge the urea. The acid urease of Enterobacter sp. R-SYB082, with lower optimum pH than the widely used commercial acid urease, exhibited a urea removal rate ...
Ko J A - - 2011
Allyl isothiocyanate (AITC) is a well-recognized antimicrobial agent but, application of AITC to food systems is limited due to its high volatility and strong odor. This study was performed to overcome the volatility of AITC by encapsulation using gum Arabic and chitosan and to investigate the effect of microencapsulated AITC ...
Sajewicz Mieczysław - - 2011
We employ high performance liquid chromatography with diode array, evaporative light scattering and mass spectrometric detection to monitor the oligomerization of L-lactic acid in pure acetonitrile and in 70% aqueous ethanol. The production of higher oligomers appears to proceed in an oscillatory fashion. A model is presented that involves the ...
Gao Hong-Wen - - 2011
The CR@BaSO(4) hybrid was synthesized, characterized and used as an acid rain-indicating (ARI) material. A painted ARI umbrella was discolored after exposure to simulated acid rain of pH 5 or less and returned to the initial color after the rain stopped. Such a functionalized material may make acid rain visual ...
Martínez-Gil Ana M - - 2012
  The aim of this work was to study the influence of nitrogen compounds on the formation of volatile compounds during the alcoholic fermentation carried out with 4 nonaromatic grape varieties collected at 2 different maturation stages. To do this, Monastrell, Merlot, Syrah, and Petit Verdot grapes were collected 1 ...
Moy Yin-Soon - - 2011
In the present study, sufu, a soft cheese-like oriental fermented food, was prepared by ripening the salted-tofu cubes in Aspergillus oryzae-fermented soybean-rice koji at 37°C for 16days (16-day sufu). Sufu was further held at room temperature for another 30days (46-day sufu). The volatile components of the non-fermented tofu cubes and ...
Kurzrock Tanja - - 2011
Biotechnologically produced succinic acid has the potential to displace maleic acid and its uses. Therefore, it is of high interest for the chemical, pharmaceutical, and food industry.In addition to optimized production strains and fermentation processes, an efficient separation of succinic acid from the aqueous fermentation broth is indispensable to compete ...
Blacker Suzanne M - - 2011
Four commercially-available fruit smoothie drinks were assessed for both initial/baseline pH and titratable acidity. A commercially-available smooth orange juice drink was used as a positive control. Baseline pH and titratable acidity were measured by titrating each fruit smoothie with 0.5 mL increments of 1M sodium hydroxide (NaOH), and measuring the ...
Opperman Maretha - - 2011
Substantial evidence describes the protective effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFA) on cardiovascular diseases as well as many other conditions. Numerous fatty acid preparations are marketed for supplementing the Western diet, which is low in n-3 fats. Since these preparations may vary in their n-3 PUFA content, ...
Fuse Shinichiro - - 2011
Continuous in situ generation of phosgene and its use in acid chloride formation in a microflow system were demonstrated. The acid chloride was subsequently coupled with an amine in high yield without severe epimerization.
Castro Patricio A - - 2012
Ethanol alters the function of several members of the Cys-loop ligand-gated ion channel superfamily. Recent studies have shown that the sensitivity of the α1 glycine receptor (GlyR) to ethanol can be affected by the state of G protein activation mediated by the interaction of Gβγ with intracellular amino acids in ...
Alves S P - - 2011
In vitro batch incubations were used to study the rumen biohydrogenation of unsaturated fatty acids. An earlier study using increasing supplementation levels of stearidonic acid (18:4n-3), revealed that the rumen microbial population extensively biohydrogenates 18:4n-3 after 72 h of in vitro incubation, though several intermediates formed were not completely characterized. Therefore, ...
Yan Shaomin - - 2011
Misgurin is an antimicrobial peptide from the loach, while the hydrophobic-polar (HP) model is a way to study the folding conformations and native states in peptide and protein although several amino acids cannot be classified either hydrophobic or polar. Practically, the HP model requires extremely intensive computations, thus it has ...
Cai Hongying - - 2011
The β-mannanase gene, man5C1, was cloned from Penicillium pinophilum C1, a strain isolated from the acidic wastewater of a tin mine in Yunnan, China, and expressed in Pichia pastoris. The sequence analysis displayed the gene consists of a 1221-bp open reading frame encoding a protein of 406 amino acids (Man5C1). ...
Nakano Shinta - - 2011
Effects of Ca(OH)(2), NH(4)OH, and NaOH as neutralizing agents for efficient recovery of lactic acid was investigated. Lactic acid was produced from broken rice in a simultaneous saccharification and fermentation (SSF) process with Lactobacillus delbrueckii. Consumption of glucose (from broken rice) by the cells and the cell growth were the ...
Shan Junhong - - 2011
In this study, the effects of pH, bromide and nitrite on the formation of halonitromethanes (HNMs) and trihalomethanes (THMs) from eight amino acids (glycine, alanine, serine, cysteine, aspartic acid, glutamic acid, lysine and histidine) and four amino sugars (glucosamine, galactosamine, N-acetylglucosamine and N-acetylneuraminic acid) were examined for chlorination and ozonation ...
Miranda J R - - 2011
The present work deals with the optimization of cellular disruption and sugar extraction from the microalgae Scenedesmusobliquus (Sc) for bioethanol production. Among the physical and physicochemical methods tested, the best results were obtained with acid hydrolysis by H(2)SO(4) (2N), at 120°C for 30min and using dried biomass. The sugar extraction ...
Wang Peng - - 2011
A new type of in situ product removal (ISPR) technique of expanded bed adsorption (EBA) bioreactor was studied to simultaneously produce extracellular propionic acid and intracellular vitamin B12 by Propionibacterium freudenreichii CICC 10019. Resin screening experiments showed that the ZGA330 resin have the best biocompatibility and highest adsorption for propionic ...
Zhao Yong-Hong - - 2011
The synthesis and characterization of organic-inorganic hybrid materials that selectively capture sugars from model biomass hydrolysis mixtures are reported. 3-Aminophenylboronic acid (PBA) groups that can reversibly form cyclic esters with 1,2-diols and 1,3-diols including sugars are attached to mesoporous SBA-15 via different synthetic protocols. In the first route, a coupling ...
Maia M R G - - 2011
Dietary supplementation of stearidonic acid (SDA; 18:4n-3) has been considered to be a possible strategy to increase n-3 unsaturated fatty acid content in ruminant products, however little is known about its metabolism in the rumen. In vitro batch incubations were carried out with bovine ruminal digesta to investigate the metabolism ...
Lee Hee-Seok - - 2011
The effects of (14)C-labelled precursor feeding on the production of cyclic hexadepsipeptides were investigated by the mycelium of F. oxysporum KFCC11363P producing beauvericin along with enniatins H, I, and MK1688. Most (14)C-phenylalanine and (14)C-valine were incorporated easily into the biosynthetic pathway of (14)C-labelled beauvericin in vivo by the mycelium. However, ...
Yamasaki Yasuhiro - - 2011
Alginate is a natural acidic linear polysaccharide that is produced by brown seaweeds. It is currently used in a broad range of commercial enterprises, such as the food and medical products industries. Recent evidence has demonstrated that alginate oligosaccharides may function as growth promoting agents for certain plant cells, including ...
Nellis David F - - 2011
PURPOSE: The use of recombinant human interleukin (rhIL)-15 as a potential therapeutic immune modulator and anticancer agent requires pure, stable preparations. However, purified rhIL-15 preparations readily accumulated heterogeneities. We sought to improve rhIL-15 stability through process, formulation, and targeted amino acid changes. METHODS: The solution state of rhIL-15 versus buffer ...
Gonzalez Juan A - - 2011
BACKGROUND: Quinoa is a good source of protein and can be used as a nutritional ingredient in food products. This study analyses how much growing region and/or seasonal climate might affect grain yield and nutritional quality of quinoa seeds. RESULTS: Seeds of ten quinoa cultivars from the Andean highlands (Bolivia/Argentina ...
Sun Dan - - 2011
Formic acid is a highly energetic electron donor but it has previously resulted in low power densities in microbial fuel cells (MFCs). Three different set anode potentials (-0.30, -0.15, and +0.15 V; vs a standard hydrogen electrode, SHE) were used to evaluate syntrophic interactions in bacterial communities for formic acid degradation ...
Goli T - - 2011
The pH value is a fundamental datum to be monitored during marination. A method is proposed for calculating the evolution of pH of turkey meat cubes during marination in an acetic acid solution. It is based on measurement of the buffering capacity by acidification using a strong acid. A calculation ...
Rawal Rachna - - 2011
A chitosan-glutaraldehyde crosslinked uricase was immobilized onto Prussian blue nanoparticles (PBNPs) absorbed onto carboxylated multiwalled carbon nanotube (c-MWCNT) and polyaniline (PANI) layer, electrochemically deposited on the surface of Au electrode. The nanohybrid-uricase electrode was characterized by scanning electron microscopic (SEM), Fourier transform infrared spectroscopy (FTIR) and cyclic voltammetry. An amperometric ...
Wang Cheng-Cheng - - 2011
A neutralizing agent combination strategy was developed to enhance the succinic acid production by Actinobacillus succinogenes ATCC 55618. First, a maximal succinic acid production of 48.2 g/L was obtained at a culture pH of 7.5. Second, NaOH and KOH were screened to identify the optimal neutralizing agent for pH control. However, ...
Nagel Ulrike - - 2011
A short and effective synthesis of ethyl 3-(3-aminophenyl)propanoate is presented, employing a tandem Knoevenagel condensation/alkylidene reduction of 3-nitrobenzaldehyde with Meldrum's acid in TEAF (triethylammonium formate) followed by reduction of the intermediate 3-(3-nitrophenyl)propanoic acid by stannous chloride in ethanol. The use of stannous chloride as the reducing agent in ethanol enabled ...
Park Sang-Jin - - 2011
As energy and environment have become urgent issues, there has been increasing needs to develop alternative energy source, such as microalgal bio-fuel. In this study, we investigated the growth and lipid contents of microalgae Nannochloris oculata under various environmental conditions for biodiesel production. Our results indicated that biomass productivities of ...
Liu Changhui - - 2011
The effects of exposure concentration on the bioaccumulation of four perfluorinated chemicals (PFCs): perfluorooctanesulfonate (PFOS), perfluoroocanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorodecanoic acid (PFDA), was investigated using green mussels, Perna viridis. Mussels were exposed to concentrations of 1 μgL(-1) and 10 μgL(-1) of each PFC for 56 days, and ...
Ariffin Fazilah - - 2011
BACKGROUND: C. asiatica was exposed to various fermentations: no fermentation (0 min), partial fermentation (120 min) and full fermentation (24 h). Total phenolic content (TPC) and ferric-reducing antioxidant power (FRAP) of C. asiatica infusions were studied as a function of water temperature (60, 80 or 100 °C), the brewing stage ...
Tietel Zipora - - 2011
In order to elucidate the roles of ethanol fermentation metabolism in causing off-flavors, we exposed 'Mor' mandarins to anaerobic atmospheres for 0, 2, 4, 7 and 10 days, to gradually increase juice ethanol and acetaldehyde levels through enhanced anaerobic respiration. Exposure to anaerobic atmosphere caused progressive decline in fruit sensory ...
Javani Azita - - 2011
The cost of biodiesel production can be reduced by a number of strategies such as utilization of waste cooking oils and non-edible plant oils as well as implementation of improved separation technologies. In addition, processes dealing with the glycerol by-product can have economic benefits. In the present study, acidification of ...
Kaneko Shu - - 2011
An investigation by Aroma Extract Dilution Analysis (AEDA) of the aroma concentrate of soy milk made from a major Japanese soybean cultivar, Fukuyutaka (FK), revealed 20 key aroma compounds as Flavor Dilution (FD) factors of not less than 43. Among them, 2-isopropyl-3-methoxypyrazine, cis-4,5-epoxy-(E)-2-decenal, trans-4,5-epoxy-(E)-2-decenal, 3-hydroxy-4,5-dimethyl-2(5H)-furanone, and 2'-aminoacetophenone were identified as ...
Kim Tae-Hyeong - - 2011
A batch test and continuous operation were performed to identify the effect of lactate on hydrogen production at pH 4.5. When the initial lactic acid concentration was increased from 0 to 8g/L in the batch test, the hydrogen yield also increased from 1.41 to 1.72mol-H(2)/mol-glucose. The system exhibited a long ...
Hu Shengjun - - 2011
The feasibility of using crude glycerol to liquefy soybean straw for the production of biopolyols and polyurethane (PU) foams was investigated in this study. Liquefaction conditions of 240°C, >180min, 3% sulfuric acid loading, and 10-15% biomass loading were preferred for the production of biopolyols with promising material properties. Biopolyols produced ...
Guo Xiao-Feng - - 2011
The optimal conditions for the production of γ-aminobutyric acid (GABA) by the marine yeast isolate Pichia anomala MR-1 strain appeared to be completely different from those required for growth and biomass production of the yeast strain. By proper reaction temperatures and pH levels, the efficiency of GABA production was improved ...
Earles Mason - - 2011
The oriented strand board (OSB) biorefinery is an emerging technology that could improve the building, transportation and chemical sectors' environmental profile. By adding a hot water extraction stage to conventional OSB panel manufacturing, hemicellulose polysaccharides can be extracted from wood strands and converted to renewably sourced ethanol and acetic acid. ...
Remling Nicole - - 2011
The aim of the present study was to determine the effects of the potential methane reducer fumaric acid on the fattening performance and acid-base balance of growing bulls fed two different silage types as roughage (maize and grass silage). A total of 62 fattening bulls (German Holstein breed, initial body ...
Pereira Susana R - - 2011
The fermentation of reducing sugars from hardwood (eucalypt) spent sulphite liquor (HSSL) into ethanol by Pichia (Scheffersomyces) stipitis is hindered by concomitant inhibitors of microbial metabolism. The conditions for the HSSL biological treatment step by Paecilomyces variotii were evaluated and optimised. Two different strategies of reactor operation were compared using ...
Cowieson A J - - 2011
1. A total of 240 Ross 308 broilers were used to investigate the effect of sodium (1·5 or 2·5 g/kg), phytate-P (0 or 3·2 g/kg), and phytase (0 or 1000 FTU/kg; 2x2x2 factorial) on endogenous amino acid flow using the enzyme-hydrolysed casein method. 2. The ingestion of phytate increased endogenous amino acid ...
Ebadi M R - - 2011
Accurate knowledge of true digestible amino acid (TDAA) contents of feedstuffs is necessary to accurately formulate poultry diets for profitable production. Several experimental approaches that are highly expensive and time consuming have been used to determine available amino acids. Prediction of the nutritive value of a feed ingredient from its ...
Fenton Tanis R - - 2011
Recently the lay press has claimed a hypothetical association among dairy product consumption, generation of dietary acid, and harm to human health. This theoretical association is based on the idea that the protein and phosphate in milk and dairy products make them acid-producing foods, which cause our bodies to become ...
Panagiotopoulos I A - - 2011
The production of fermentable substrates from barley straw under various process conditions was studied. Pretreatment included chemical pretreatment with dilute-acid followed by enzymatic hydrolysis; the pretreatment conditions were expressed in a combined severity factor, CS, which ranged in the present study from -1.6 to 1.1. Considering the production of fermentable ...
1 2 3 4 5 6 7 8 9 10 >