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Bowman David T DT Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St W., Hamilton, ON, Canada, L8S 4 - - 2014
Naphthenic acids (NAs) accumulate in oil sands process-affected water (OSPW) as a result of the water-based extraction processes, and represent one of the toxic fractions in OSPW. They exist as a complex mixture and so the development of an analytical method to characterize and quantify individual acids has been an ...
Xiao Han - - 2014
BackgroundRecent advances in synthesizing valuable chemicals such as organic acids from low-cost renewable biomass through microbial fermentation have attracted great attention. However, the toxicity of organic acids presents a key challenge to the development of an economically viable fermentation process. Therefore, a platform organism that not only produces organic acids ...
Henning Christian C Martin-Luther-University Halle-Wittenberg, - - 2014
Maillard α-dicarbonyl compounds are known as central intermediates in advanced glycation endproduct (AGE) formation. Glucose is the primary source of energy for the human body whereas L-threo-ascorbic acid (vitamin C) is an essential nutrient, involved in a variety of enzymatic reactions. Thus, the Maillard degradation of glucose and ascorbic acid ...
van der Born Dion D Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1085c, 1081 HV Amsterdam (The - - 2014
Herein, we describe a valuable method for the introduction of the [(18) F]CF3 group into arenes with highly improved specific activity by the reaction of [(18) F]trifluoromethane with aryl iodides or aryl boronic acids. This [(18) F]trifluoromethylation reaction is the first to be described in which the [(18) F]CF3 products ...
Robertson Jeremy J Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK. - - 2014
Covering: July 2001 to December 2012This review covers pyrrolizidine alkaloids isolated from natural sources. Topics include: aspects of structure, isolation, and biological/pharmacological studies; total syntheses of necic acids, necine bases and closely-related non-natural analogues.
Jiang Juncong - - 2014
Superacids, defined as acids with Hammett acidity function H0 ≤ -12, are useful materials, but a need exists for new, designable solid state systems. Here, we report superacidity in a sulfated metal-organic framework (MOF) obtained by treating the microcrystalline form of MOF-808 [MOF-808-P: Zr6O5(OH)3(BTC)2(HCOO)5, BTC = 1,3,5-benzenetricarboxylate] with aqueous sulfuric ...
Harris William S WS Sanford School of Medicine, University of South Dakota, Sioux Falls, SD; Health Diagnostic Laboratory, Inc., Richmond, VA; OmegaQuant Analytics, LLC, Sioux Falls, SD - - 2014
The once-settled roles of all dietary fatty acid classes vis-à-vis coronary heart disease (CHD) seem to be under fire these days. For decades it had been received wisdom that "saturated fats are bad," and that margarines should replace butter to reduce risk for heart attacks. But a recent Time magazine ...
Hu Linhua L Department of Chemistry, ‡Department of Materials Science and Engineering, Northwestern University , Evanston, Illinois 60208, United - - 2014
Oleic acid, an 18-carbon chain fatty acid, has been widely used as a surfactant to fabricate colloidal nanocrystals. In previous work, we discovered a lamellar microemulsion strategy to fabricate sub-20 nm SrTiO3 nanocuboids using oleic acid and oleate species. Here, we demonstrate (i) the general synthesis with lamellar microemulsions of ...
Franchini Massimo M aDepartment of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantova bScientific Direction, IRCCS Ca' Granda Maggiore Policlinico Hospital Foundation, Milan, - - 2014
This review provides a summary of the most recent clinical trials evaluating the hemostatic agents for the treatment of coagulopathy associated with critical bleeding. In particular, antifibrinolytic agents (i.e., aprotinin, tranexamic and ε-aminocaproic acids), desmopressin, recombinant activated factor VII, fibrinogen and prothrombin complex concentrates are evaluated. Among the various therapeutic ...
Bejarano Eloy E Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Chanin Building Room 502, 1300 Morris Park Avenue, Bronx, NY, 10461, - - 2014
Autophagy is a catabolic pathway responsible for the maintenance of the tissue and organism homeostasis. Several amino acids regulate autophagic activity in different tissues, such as liver and muscle, but much less is known about this regulation in the brain. The lack of autophagy in neurons leads to a strong ...
Amako Tomoyuki T Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3-4-1 Kowakae, Higashi-Osaka, Osaka 577-8502, Japan. - - 2014
Tethering four 1- versus 2-naphthyls to the same chiral scaffold derived from tartaric acid led to oppositely signed circularly polarized luminescence (CPL) and circular dichroism (CD) in solution, which not only reveals the decisive role of the spatial arrangement of chromophores/fluorophores in determining the chiroptical behaviors but also provides us ...
Messner J J Lehrstuhl für Chemische Reaktionstechnik der Universität Erlangen-Nürnberg (FAU), Egerlandstrasse 3, D-91058 Erlangen, Germany. - - 2014
The isomerisation reaction of 1,4-dichlorobenzene leading to the thermodynamically favoured and technically desired 1,3-dichlorobenzene has been studied comparing highly acidic chloroaluminate melts with organic imidazolium and alkali metal ions. Interestingly, the inorganic melts show much higher reactivity and full recyclability if small AlCl3 losses are compensated and the reaction is ...
Shan Letian L Institute of Orthopaedics and Traumatology, Zhejiang Chinese Medical University, No. 548 Binwen Road, Binjiang District, Hangzhou 310053, China. - - 2014
Lumbar disc herniation (LDH) is a commonly occurring disease, threatening human health and life quality. Lack of a gold standard of diagnosis has hindered the efficiency and efficacy of clinical therapy against LDH. Traditional Chinese medicine (TCM) has provided an experience-based but subjective diagnosis system for LDH, demanding objective evidence ...
Bermúdez Celina C Grupo de Espectroscopia Molecular (GEM), Edificio Quifima Laboratorios de Espectroscopia y Bioespectroscopia, Parque Científico UVa, Universidad de Valladolid, 47011 Valladolid (Spain) - - 2014
Histidine is an important natural amino acid, involved in many relevant biological processes, which, because of its physical properties, proved difficult to characterize experimentally in its neutral form. In this work, neutral histidine has been generated in the gas phase by laser ablation of solid samples and its Nε H ...
Yu Xiang X Department of Chemistry, Renmin University of China, Beijing 100872 (P. R. - - 2014
Polydopamine (PDA) generated by the oxidative self-polymerization of dopamine shows great potential for surface modification. Observed PDA nanostructures are nanoparticles and thin films. The formation mechanism of PDA is still unclear; thus, the manipulation of PDA nanostructures is a big challenge. In this study, we first demonstrated that folic acid ...
Gajzlerska Wanda W Medical University of Warsaw, Department of Drug Technology & Pharmaceutical Biotechnology, Banacha 1a, Warszawa 02-097, Poland. Electronic address: - - 2014
Tacrolimus, a 23-membered polyketide macrolide, is isolated as a metabolite from the whole fermentation broth of Streptomyces species. This potent immunosuppressive calcineurin inhibitor has been widely used in various fields of medicine, including transplantology, dermatology and pharmacotherapy of autoimmune diseases. The current study was focused on optimisation of tacrolimus biosynthesis ...
Passo Tsamo Claudine Valérie CV Institut des Sciences de la Vie, UCLouvain, 1348 Louvain-la-Neuve, Belgium; Centre for Food and Nutrition Research, Institute of Medical Research and Medicinal Plant Studies, P.O. Box 6163, Yaounde, - - 2015
The present study investigated the phenolic profiles of the pulp and peel of nine plantain cultivars and compared them to those of two dessert bananas of commercial interest (Grand Nain and Gros Michel), alongside a newly created hybrid, resistant to black sigatoka disease (F568). Identification and quantification of phenolic compounds ...
Ruiz Antonieta A Instrumental Analysis Department, Faculty of Pharmacy, University of Concepción, PO Box 160-C, Concepción, Chile; Department of Chemical Sciences and Natural resources, University of La Frontera, Casilla 54-D, Temuco, - - 2015
Diverse edible berries are native to the Patagonian region of Southern Chile. These berries are underused because their nutritional properties are relatively unknown. In this work, the profiles and concentrations of hydroxycinnamic acid derivatives and flavonols, and the antioxidant capacity of the berry extracts, were studied using HPLC-DAD-ESI-MS/MS and CUPRAC ...
Novoa-Díaz D D Sensor Systems Group, Department of Electronic Engineering, Universitat Politècnica de Catalunya, Jordi Girona 1-3, 08034 Barcelona, - - 2014
The progress of malolactic fermentation in red wines has been monitored by using ultrasonic techniques. The evolution of ultrasonic velocity of a tone burst 1MHz longitudinal wave was measured, analyzed and compared to those parameters of oenological interest obtained simultaneously by analytical methods. Semi-industrial tanks were used during measurements pretending ...
Tang Lirong - - 2012
Esterified cellulose nanocrystals (E-CNCs) are cellulose derivatives that could be applied in biomedical and chemical industries. E-CNCs were prepared with cellulose pulp using a mixture of 17.5M acetic and 18.4M sulfuric acid with the aid of ultrasonication. The effects of esterification time (3-7h), ultrasonication time (with a frequency of 40kHz, ...
Passos Priscila Pereira - - 2012
Essential fatty acids play a crucial role in the activity of several neurotransmission systems, especially in the monoaminergic systems involved in cognitive and motor aspects of behavior. The present study investigated whether essential fatty acid dietary restriction over two generations could differentially affect dopaminergic cell populations located in the substantia ...
Martin Melanie A MA Integrative Anthropological Sciences, University of California Santa Barbara, Santa Barbara, California 93106-3210, USA. - - 2012
Breast milk fatty acid (FA) composition varies greatly among individual women, including in percentages of the long-chain polyunsaturated FAs (LCPUFA) 20:4n-6 (arachidonic acid, AA) and 22:6n-3 (docosahexaenoic acid, DHA), which are important for infant neurological development. It has been suggested that owing to wide variation in milk LCPUFA and low ...
Saga Linda C - - 2012
This study investigated data obtained from whole blood fatty acid (FA) composition of 3476 Norwegian and Swedish individuals, which provided background information including age, gender, nationality and self-motivated n-3 supplement consumption. The aim of this paper was to statistically relate this background information on the subjects to their whole blood ...
Yokota S - - 2012
The fatty acid synthase (FASN) and stearoyl-CoA desaturase (delta-9-desaturase) (SCD) genes affect fatty acid composition. This study evaluated the contributions of polymorphisms of these genes on fatty acid composition in muscle in two different populations: 1189 and 1058 Japanese Black cattle from the Miyagi and the Yamagata populations respectively. We ...
Bi Hongkai - - 2012
Signal molecules of the diffusible signal factor (DSF) family have been shown recently to be involved in regulation of pathogenesis and biofilm formation in diverse Gram-negative bacteria. DSF signals are reported to be active not only on their cognate bacteria, but also on unrelated bacteria and the pathogenic yeast, Candida ...
Wang Xiaoxu - - 2012
The transition period is a severe challenge to dairy cows. Glucose supply cannot meet demand and body fat is mobilized, potentially leading to negative energy balance (NEB), ketosis, or fatty liver. Propionate produces glucose by gluconeogenesis, which depends heavily on the number and species of microbes. In the present study, ...
Palacios-Chaves Leyre - - 2012
The brucellae are facultative intracellular pathogens of mammals that are transmitted by contact with infected animals or contaminated materials. Several major lipidic components of the Brucella cell envelope are imperfectly recognized by innate immunity thus contributing to virulence. These components carry large proportions of acyl chains of lactobacillic acid, a ...
Molla Gianluca - - 2012
D: -Amino acids play several key roles and are widely diffused in living organisms, from bacteria (in which D: -alanine is a component of the cell wall) to mammals (where D: -serine is involved in glutamatergic neurotransmission in the central nervous system). The study of the biological processes involving D: ...
Li Robert W - - 2012
The capacity of the rumen microbiota to produce volatile fatty acids (VFAs) has important implications in animal well-being and production. We investigated temporal changes of the rumen microbiota in response to butyrate infusion using pyrosequencing of the 16S rRNA gene. Twenty one phyla were identified in the rumen microbiota of ...
Wallace John L - - 2012
The mechanisms underlying the ability of nonsteroidal anti-inflammatory drugs (NSAIDs) to cause ulceration in the stomach and proximal duodenum are well understood, and this injury can largely be prevented through suppression of gastric acid secretion (mainly with proton pump inhibitors). In contrast, the pathogenesis of small intestinal injury induced by ...
Lanéelle Marie-Antoinette - - 2011
Corynebacterineae are characterized by the presence of long-chain lipids, notably mycolic acids (α-alkyl, β-hydroxy fatty acids), the structures of which are genus-specific. Mycolic acids from two environmental strains, Amycolicicoccus subflavus and Hoyosella altamirensis, were isolated and their structures established using a combination of mass spectrometry analysis, 1H-NMR spectroscopy and chemical ...
Li Wen-Juan - - 2011
The aim of this study was to investigate the possibility of ethanol-soluble acidic components (ESAC) from Ganoderma atrum as a novel source against bacteria and oxidation in food industry. The qualitative analysis of ESAC was based on liquid chromatography-mass spectrometry (LC/MS) and eight ganoderic acids were identified in ESAC. Its ...
Cui Yanhua - - 2011
The Gram-positive bacterium Lactobacillus delbrueckii subsp. bulgaricus is of vital importance to the food industry, especially to the dairy industry. Two component systems (TCSs) are one of the most important mechanisms for environmental sensing and signal transduction in the majority of Gram-positive and Gram-negative bacteria. A typical TCS consists of ...
Nyanga-Koumou Armand P - - 2011
Regulation of the cytoplasmic or internal pH (pHin) is a fundamental requirement for the survival and viability of bacteria. The optimum pHin for most bacteria is near the neutral point (pH 7.0). Therefore, bacteria may have some strategies to adapt themselves to the acidity or alkalinity of cytoplasm. As other ...
Wells A - - 2011
Aims:  To investigate the impact of acetaldehyde and pyruvic acid bound sulfur dioxide on wine lactic acid bacteria. Methods and Results:  Growth studies were performed where Oenococcus oeni, Pediococcus parvulus, P. damnosus, and Lactobacillus hilgardii were inoculated into media containing various concentrations of acetaldehyde or pyruvic acid and an equimolar ...
Fischer Carol L - - 2012
There is growing evidence that the role of lipids in innate immunity is more important than previously realized. How lipids interact with bacteria to achieve a level of protection, however, is still poorly understood. To begin to address the mechanisms of antibacterial activity, we determined MICs and minimum bactericidal concentrations ...
Wang Jifu - - 2011
We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating ...
Estrada J D - - 2011
Fortified dairy products appeal to a wide variety of consumers and have the potential to increase sales in the yogurt industry and help increase intake of long-chain n-3 fatty acids. The objectives of this study were to develop a strawberry yogurt containing microencapsulated salmon oil (MSO; 2% wt/vol) and evaluate ...
Li Ming - - 2011
An urgent need exists for HIV-1 microbicides. Here, we describe the in vivo testing of lactic acid bacteria bioengineered to secrete cyanovirin-N. We fed pigtail macaques a yogurt formulation that used bioengineered strains as a starter culture. Cyanovirin-N expression could be detected in the rectal vault during and immediately after ...
Yu Bo - - 2011
Lactobacillus rhamnosus is a type of probiotic bacteria with industrial potential for L-lactic acid production. We announce the draft genome sequence of L. rhamnosus CASL (2,855,156 bp with a G+C content of 46.6%), which is an efficient producer of L-lactic acid from cheap, nonfood substrate cassava with a high production ...
Quévrain Elodie - - 2011
The fatty acid composition of the temperate calcareous marine sponge Leuconia johnstoni Carter 1871 (Calcaronea, Calcarea) was characterized for the first time in specimens collected off the Brittany coast of France over four years from October 2005 to September 2008. Forty-one fatty acids (FA) with chain lengths ranging from C(14) to ...
de Carvalho Carla C C R - - 2011
Bioremediation of contaminated sites is rarely performed in nature under ideal growth conditions for bacteria. Extremophiles can grow at extreme values of temperature, pH, ionic strength and metal concentrations, etc., but it may be difficult to find and isolate those possessing the required metabolic activities. In the present work, Rhodococcus ...
Rizzello Carlo G - - 2011
This study aimed to exploit the potential of sourdough lactic acid bacteria to release lunasin during fermentation of cereal and nonconventional flours. The peptidase activities of a large number of sourdough lactic acid bacteria were screened using synthetic substrates. Selected lactic acid bacteria were used as sourdough starters to ferment ...
Stafford G G Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. - - 2012
Periodontal pathogens, like any other human commensal or pathogenic bacterium, must possess both the ability to acquire the necessary growth factors and the means to adhere to surfaces or reside and survive in their environmental niche. Recent evidence has suggested that sialic acid containing host molecules may provide both of ...
Hoyle Parks A R - - 2011
Growth of pathogenic organisms such as Escherichia coli O157:H7 and Salmonella spp. can be inhibited in ground beef though addition of certain lactic acid producing bacteria (LAB; Lactobacillus acidophilus NP51, Lactobacillus crispatus NP35, Pediococcus acidilactici, and Lactococcus lactis ssp. Lactis). This study evaluated the effects of LAB inclusion on the ...
Hino Shingo - - 2011
We evaluated the ameliorating effects of short-chain inulin-like fructans (SIF) with different degrees of polymerization (DP) on the healing stage of trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. The rats were assigned to 3 groups 10 d after the colitis induction, and fed for 24 d on a control diet ...
Dupuis Stephanie N - - 2011
Streptomyces venezuelae ISP5230 is recognized for the production of chloramphenicol and the jadomycin family of natural products. The jadomycins are angucycline natural products containing a unique oxazolone ring incorporating an amino acid present in the minimal culture media. Substitution of different amino acids results in products of varying biological activity. ...
Zanet Caio Gorgulho - - 2011
Acid erosion is a superficial loss of enamel caused by chemical processes that do not involve bacteria. Intrinsic and extrinsic factors, such as the presence of acid substances in the oral cavity, may cause a pH reduction, thus potentially increasing acid erosion. The aim of this study was to evaluate ...
Romano Ariel A - - 2012
Bacteria use small diffusible molecules to exchange information in a process called quorum sensing (QS). An important class of quorum sensing molecules used by Gram-negative bacteria is the family of N-acylhomoserine lactones (HSL). It was recently discovered that a degradation product of the QS molecule 3-oxo-C(12)-homoserine lactone, the tetramic acid ...
Huang Xiang-Feng - - 2011
Considering that the surface properties of demulsifying cells correlate with their demulsification efficiency, the demulsifying bacteria Alcaligenes sp. S-XJ-1 with various surface properties were obtained using different vegetable oils as carbon sources. The results show that better performance was achieved with demulsifying bacteria S-XJ-1 possessing a relatively high cell surface ...
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