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Cuellar-Bermudez Sara P SP Cátedra de Bioprocesos Ambientales, Centro del Agua Para América Latina y el Caribe, Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Nuevo Leon, 64849, - - 2014
The marked trend and consumers growing interest in natural and healthy products have forced researches and industry to develop novel products with functional ingredients. Microalgae have been recognized as source of functional ingredients with positive health effects since these microorganisms produce polyunsaturated fatty acids, polysaccharides, natural pigments, essential minerals, vitamins, ...
Granato Daniel D RIKILT - Institute of Food Safety, Wageningen University and Research Centre, P.O. Box 230, 6700 AE, Wageningen, The Netherlands; Food Quality and Design Group, Wageningen University and Research Centre, P. O. Box 17, 6700 AA, Wageningen, The Netherlands; Food Science and Technology Graduate Program, State University of Ponta Grossa, Av. Carlos Cavalcanti, 4748, 84030-900, Ponta Grossa, - - 2014
The European Union registered a consumption of about 10.7 million liters of juices in 2011 and great part of this amount is imported from other countries, which makes the monitoring of their quality essential. This work was aimed to map the quality of various juices from different botanical origins from ...
Fimmel Elena E Institute of Applied Mathematics, Faculty for Computer Sciences, Mannheim University of Applied Sciences, 68163 Mannheim, Germany. Electronic address: - - 2014
Circular codes are putative remnants of primeval comma-free codes and are potentially involved in detecting and maintaining the normal reading frame in protein coding sequences. In Michel and Pirillo (2013b) it was shown by computer algorithm that no maximal trinucleotide circular code can encode more than eighteen different amino acids ...
Al-Jaghbeer Mohammed M Center for Critical Care Nephrology, CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, - - 2014
Acid-base disturbances are very common in critically ill and injured patients as well as contribute significantly to morbidity and mortality. An understanding of the pathophysiology of these disorders is vital to their proper management. This review will discuss the etiology, pathophysiology and treatment of acid-base disturbances in intensive care patients-with ...
Hernando Elier E Departamento de Química Orgánica, Universidad Autónoma de Madrid (UAM), Facultad de Ciencias, Cantoblanco 28049 Madrid - - 2014
A practical copper-catalyzed direct nitration of protected anilines, by using one equivalent of nitric acid as the nitrating agent, has been developed. This procedure features mild reaction conditions, wide structural scope (with regard to both N-protecting group and arene substitution), and high functional-group tolerance. Dinitration with two equivalents of nitric ...
Wu Peiwen P Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, - - 2014
In this review, we summarize recent progress in the application of synchrotron-based spectroscopic techniques for nucleic acid research that takes advantage of high-flux and high-brilliance electromagnetic radiation from synchrotron sources. The first section of the review focuses on the characterization of the structure and folding processes of nucleic acids using ...
Ghasemifard Samaneh S Metabolic Research Unit, School of Medicine, Deakin University, Geelong, VIC, - - 2014
This review considers the bioavailability in humans of different forms of long chain omega 3 polyunsaturated fatty acids (n-3 LC-PUFA), including ethyl esters (EE), free fatty acids (FFA), triacylglycerols (TAG) and phospholipids (PL). The retrieved studies include short and long term studies, which were highly heterogeneous in their design making ...
Abi-Ghanem Josephine J CNRS, UMS 3033, IECB, F-33600 Pessac, - - 2014
Nucleic acids are diverse polymeric macromolecules that are essential for all life forms. These biomolecules possess a functional three-dimensional structure under aqueous physiological conditions. Mass spectrometry-based approaches have on the other hand opened the possibility to gain structural information on nucleic acids from gas-phase measurements. To correlate gas-phase structural probing ...
von Schacky Clemens C Omegametrix, Martinsried, and Preventive Cardiology, Ludwig Maximilians-University, Munich, both in - - 2014
The Omega-3 Index is defined as erythrocyte eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and represents an individual's status in these two marine omega-3 fatty acids. A target range of 8 - 11% has been suggested, because values below predispose to cardiovascular events, especially sudden cardiac death, as well as ...
Qiu Cuicui C School of Environment, State Key Joint Laboratory of Environmental Simulation and Pollution Control, Tsinghua University, Beijing 100084, - - 2014
Electrolysis and ozonation are two commonly used technologies for treating wastewaters contaminated with nitrophenol pollutants. However, they are often handicapped by their slow kinetics and low yields of total organic carbon (TOC) mineralization. To improve TOC mineralization efficiency, we combined electrolysis using a boron-doped diamond (BDD) anode with ozonation (electrolysis-O3) ...
Yang E E State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, The Chinese Academy of Sciences , Fuzhou, Fujian 350002, P. R. - - 2014
Two enantiomorphic metal-organic frameworks with zeotype SOD topology have been successfully synthesized from enantiopure l-alanine and d-alanine, respectively, which demonstrates the feasibility of fabricating MOFs that integrate the 4-connected zeotype topologies and homochiral nature by the employment of enantiopure amino acids.
Yin Jing - - 2014
A silver-catalyzed trans-addition of carboxylic acids to ynol ethers is described. The reaction has broad scope with respect to carboxylic acids and ynol ethers, delivering (Z)-alpha-alkoxy enol esters in good yields with excellent regio- and stereoselectivity. Meaningfully, the Ni-catalyzed selective coupling of alkenyl C-OPiv bonds of (Z)-alpha-alkoxy enol esters with ...
Costentin Cyrille - - 2014
Molecular catalysis of H2 production from the electrochemical reduction of acids by transition metal complexes is one of the key issues of modern energy challenges. Does it proceed heterolytically (through reaction of an initially formed metal hydride with the acid) or homolytically (through symmetrical coupling of two molecules of hydride) ...
Dubey Sumit M SM Chemical Engineering Department, Institute of Chemical Technology, Matunga, Mumbai 40019, - - 2014
The present work reports the intensification aspects for the synthesis of fatty acid methyl esters (FAME) from a non-edible high acid value Nagchampa oil (31mg of KOH/g of oil) using two stage acid esterification (catalyzed by H2SO4) followed by transesterification in the presence of heterogeneous catalyst (CaO). Intensification aspects of ...
Leung Kin Sum - - 2014
Abstract Isoprostanoids and isofuranoids are lipid mediators that can be formed from omega-3 and omega-6 polyunsaturated fatty acids (PUFAs). F2-isoprostanes formed from arachidonic acid, especially 15-F2t-isoprostane are commonly measured in biological tissues for decades as the biomarker for oxidative stress and diseases. Recently, other forms of isoprostanoids derived from adrenic, ...
Klein Matthias S - - 2014
Metabolite profiles of individuals possessing either the cardiovascular risk or protective variants of the low-density lipoprotein cholesterol (LDL-C) associated 1p13.3 locus of the SORT1 gene (rs646776) were analyzed. Serum metabolites and lipids were assessed using LC-MS based metabolomics in a healthy young population (N=138, 95 males, 43 females). While no ...
Li Jun - - 2014
Jarosites and schwertmannite can be formed in the unsaturated oxidation zone of sulfide-containing mine waste rock and tailings together with ferrihydrite and goethite. They are also widely found in process wastes from electrometallurgical smelting and metal bioleaching and within drained coastal lowland soils (acid-sulfate soils). These secondary minerals can temporarily ...
Tolonen Emma-Tuulia ET University of Oulu, Department of Chemistry, FIN-90014 University of Oulu, P.O. Box 3000, - - 2014
The aim of this research was to investigate whether by-products from quicklime manufacturing could be used instead of commercial quicklime (CaO) or hydrated lime (Ca(OH)2), which are traditionally used as neutralization chemicals in acid mine drainage treatment. Four by-products were studied and the results were compared with quicklime and hydrated ...
Erlinger Serge S University of Paris 7, 5, rue Thomas Mann, 75013 Paris, France. Electronic address: - - 2014
The authors report the case of a child with extreme elevation of serum bile acid concentration, without pruritus, symptomatic cholestasis, liver disease, or abnormalities of liver function tests. Sequencing of the SLC10A1 gene, encoding NTCP (the sinusoidal uptake transporter of conjugated bile acids) revealed a single homozygous point mutation in ...
Li Jia J Inflammation and Healing Research Cluster, Genecology Research Centre, School of Science and Engineering, University of the Sunshine Coast, Qld., - - 2014
Nucleic acid amplification is an essential process in biological systems. The in vitro adoption of this process has resulted in powerful techniques that underpin modern molecular biology. The most common tool is polymerase chain reaction (PCR). However, the requirement for a thermal cycler has somewhat limited applications of this classic ...
Craide Fernanda Helena FH Policlínica Geral do Rio de Janeiro, Rio de Janeiro, RJ, - - 2014
Alkaptonuria, also called endogenous ochronosis, is a rare metabolic autosomal recessive disorder. It occurs by complete inhibition of homogentisic acid oxidase enzyme having its deposition in various tissues. Male patient, 52 years old, sought medical help complaining about progressive appearance of hyperchromic papules on the lateral edge of the second ...
Faberi Angelo A MiPAAF, Dipartimento dell'Ispettorato Centrale della tutela della Qualità e Repressione Frodi dei Prodotti Agro-alimentari, Laboratorio Centrale di Roma, 00149, Rome, - - 2014
European Regulation (EEC) 2568/91 has been setting the minimum requirements in order to allow labeling of oil as extra virgin. These general requirements, are based on physical-chemical and organoleptic parameters directly linked to the freshness and quality of the product. Isotope ratio mass spectrometry (IRMS) was demonstrated to be a ...
Asadi-Samani Majid M Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, - - 2014
Borage (Borago officinalis) is an annual herb which is cultivated for medicinal and culinary uses, although it is commercially cultivated for borage seed oil. Borage seed oil is the plant rich in the gamma-linolenic acid (26%-38%) which is used as dietary or food supplement. Other than seed oil it contains ...
Kim Se Jin SJ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, The Armed Forces Capital Hospital, Seongnam, - - 2014
Valproic acid is one of the most common antiepileptic drugs used for the treatment of several seizure disorders. A 20-year-old man presented with a sudden decline of consciousness. He had a neurosurgery operation for intracranial and intraventricular hemorrhage. Following surgery, antiepileptic medication was administered to the patient in order to ...
Danese Elisa E Clinical Biochemistry Section, Department of Life and Reproduction Sciences, University of Verona, Verona, - - 2014
Nucleic acids (NAs) constitute the backbone of cellular life permitting conservation, transmission, and execution of genetic information. In the past few years, new unexpected functions for NAs, projecting them also beyond nuclear and cellular boundaries have been recognized: circulating cell-free nucleic acids (cfNAs), histones, DNA-histone complexes, microRNAs (miRs) may have ...
El-Ansary Afaf - - 2014
Fatty acids are essential dietary nutrients, and one of their important roles is providing polyunsaturated fatty acids (PUFAs) for the growth and function of nervous tissue. Short chain fatty acids (SCFAs) are a group of compounds derived from the host microbiome that were recently linked to effects on the gut, ...
Mao Zhuxin Z Xi' an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Xi'an 710061, PR China; State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou 730000, PR - - 2015
The chemical composition of four common vetch (Vicia sativa L.) seeds was investigated to determine their nutrition value. The result shows that the seeds are low in lipid (1.55-2.74% of dry weight), and high in the unsaturated fatty acid (74.51-77.36% of total fatty acid). The ratio of essential amino acid ...
Xiao Han - - 2014
BackgroundRecent advances in synthesizing valuable chemicals such as organic acids from low-cost renewable biomass through microbial fermentation have attracted great attention. However, the toxicity of organic acids presents a key challenge to the development of an economically viable fermentation process. Therefore, a platform organism that not only produces organic acids ...
Henning Christian C Martin-Luther-University Halle-Wittenberg, - - 2014
Maillard α-dicarbonyl compounds are known as central intermediates in advanced glycation endproduct (AGE) formation. Glucose is the primary source of energy for the human body whereas L-threo-ascorbic acid (vitamin C) is an essential nutrient, involved in a variety of enzymatic reactions. Thus, the Maillard degradation of glucose and ascorbic acid ...
Mei Qingsong Q Department of Biomedical Engineering, School of Medical Engineering, Hefei University of Technology, P.O. Box 112, Tunxi road 193, Hefei, Anhui 230009, - - 2014
In this work, we reported a simple and effective upconversional nanoprobe for selective detection of hydroxyl radical (OH) and visual evaluation of OH-scavenging activities of drugs for the first time. The upconversion luminescence from NaYF4:Yb,Er nanoparticles was first quenched by carminic acid (CA) through luminescence resonance energy transfer (LRET) mechanism, ...
Giby Vettickattuparambil George VG Vettickattuparambil George Giby, Thekkuttuparambil Ananthanarayanan Ajith, Department of Biochemistry, Amala Institute of Medical Sciences, Thrissur-680 555, Kerala, - - 2014
Intrahepatic fat deposition has been demonstrated in patients with nonalcoholic fatty liver disease (NAFLD). Genetic and environmental factors are important for the development of NAFLD. Diseases such as obesity, diabetes, and hypertension have been found to be closely associated with the incidence of NAFLD. Evidence suggests that obesity and insulin ...
van der Born Dion D Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1085c, 1081 HV Amsterdam (The - - 2014
Herein, we describe a valuable method for the introduction of the [(18) F]CF3 group into arenes with highly improved specific activity by the reaction of [(18) F]trifluoromethane with aryl iodides or aryl boronic acids. This [(18) F]trifluoromethylation reaction is the first to be described in which the [(18) F]CF3 products ...
Robertson Jeremy J Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK. - - 2014
Covering: July 2001 to December 2012This review covers pyrrolizidine alkaloids isolated from natural sources. Topics include: aspects of structure, isolation, and biological/pharmacological studies; total syntheses of necic acids, necine bases and closely-related non-natural analogues.
Jiang Juncong - - 2014
Superacids, defined as acids with Hammett acidity function H0 ≤ -12, are useful materials, but a need exists for new, designable solid state systems. Here, we report superacidity in a sulfated metal-organic framework (MOF) obtained by treating the microcrystalline form of MOF-808 [MOF-808-P: Zr6O5(OH)3(BTC)2(HCOO)5, BTC = 1,3,5-benzenetricarboxylate] with aqueous sulfuric ...
Harris William S WS Sanford School of Medicine, University of South Dakota, Sioux Falls, SD; Health Diagnostic Laboratory, Inc., Richmond, VA; OmegaQuant Analytics, LLC, Sioux Falls, SD - - 2014
The once-settled roles of all dietary fatty acid classes vis-à-vis coronary heart disease (CHD) seem to be under fire these days. For decades it had been received wisdom that "saturated fats are bad," and that margarines should replace butter to reduce risk for heart attacks. But a recent Time magazine ...
Koeberle Andreas A Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany. Electronic address: - - 2014
Chemical compounds studied in this article: Curcumin (PubChem CID: 969516); epigallocatechin-3-gallate (PubChem CID: 65064); resveratrol (PubChem CID: 445154); salicylic acid (PubChem CID: 338); quercetin (PubChem CID: 5280343); prostaglandin E2 (PubChem CID: 5280360); leukotriene B4 (PubChem CID: 5280492); arachidonic acid (PubChem CID: 444899).
Hu Linhua L Department of Chemistry, ‡Department of Materials Science and Engineering, Northwestern University , Evanston, Illinois 60208, United - - 2014
Oleic acid, an 18-carbon chain fatty acid, has been widely used as a surfactant to fabricate colloidal nanocrystals. In previous work, we discovered a lamellar microemulsion strategy to fabricate sub-20 nm SrTiO3 nanocuboids using oleic acid and oleate species. Here, we demonstrate (i) the general synthesis with lamellar microemulsions of ...
Franchini Massimo M aDepartment of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantova bScientific Direction, IRCCS Ca' Granda Maggiore Policlinico Hospital Foundation, Milan, - - 2014
This review provides a summary of the most recent clinical trials evaluating the hemostatic agents for the treatment of coagulopathy associated with critical bleeding. In particular, antifibrinolytic agents (i.e., aprotinin, tranexamic and ε-aminocaproic acids), desmopressin, recombinant activated factor VII, fibrinogen and prothrombin complex concentrates are evaluated. Among the various therapeutic ...
Ho Hon Eong HE WPI-Advanced Institute for Materials Research (WPI-AIMR), Tohoku University , Sendai 980-8577, - - 2014
We have demonstrated for the first time that carboxylic acids are able to catalyze the direct hydroboration of various terminal and internal alkynes with pinacolborane without using any metal catalysts. This unprecedented catalytic hydroboration exhibits a broad functional groups compatibility, giving the corresponding alkenyl diboronates and monoboronates in good to ...
Zhang Fengge F National Engineering Research Center for Organic-based Fertilizers, Nanjing Agricultural University, Nanjing 210095, PR - - 2014
The ability to colonize on plant roots is recognized as one of the most important characteristics of the beneficial fungi Trichoderma spp. The aim of this study is to prove that the utilization of organic acids is a major trait of Trichoderma harzianum T-E5 for colonization of cucumber roots. A ...
Bejarano Eloy E Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Chanin Building Room 502, 1300 Morris Park Avenue, Bronx, NY, 10461, - - 2014
Autophagy is a catabolic pathway responsible for the maintenance of the tissue and organism homeostasis. Several amino acids regulate autophagic activity in different tissues, such as liver and muscle, but much less is known about this regulation in the brain. The lack of autophagy in neurons leads to a strong ...
Amako Tomoyuki T Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3-4-1 Kowakae, Higashi-Osaka, Osaka 577-8502, Japan. - - 2014
Tethering four 1- versus 2-naphthyls to the same chiral scaffold derived from tartaric acid led to oppositely signed circularly polarized luminescence (CPL) and circular dichroism (CD) in solution, which not only reveals the decisive role of the spatial arrangement of chromophores/fluorophores in determining the chiroptical behaviors but also provides us ...
Isobe Yosuke Y Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, - - 2014
Omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid have beneficial effects in many inflammatory disorders. Although the mechanism of eicosapentaenoic acid and docosahexaenoic acid action is still not fully defined in molecular terms, recent studies have revealed that, during the course of acute inflammation, omega-3 polyunsaturated fatty ...
Messner J J Lehrstuhl für Chemische Reaktionstechnik der Universität Erlangen-Nürnberg (FAU), Egerlandstrasse 3, D-91058 Erlangen, Germany. - - 2014
The isomerisation reaction of 1,4-dichlorobenzene leading to the thermodynamically favoured and technically desired 1,3-dichlorobenzene has been studied comparing highly acidic chloroaluminate melts with organic imidazolium and alkali metal ions. Interestingly, the inorganic melts show much higher reactivity and full recyclability if small AlCl3 losses are compensated and the reaction is ...
Shan Letian L Institute of Orthopaedics and Traumatology, Zhejiang Chinese Medical University, No. 548 Binwen Road, Binjiang District, Hangzhou 310053, China. - - 2014
Lumbar disc herniation (LDH) is a commonly occurring disease, threatening human health and life quality. Lack of a gold standard of diagnosis has hindered the efficiency and efficacy of clinical therapy against LDH. Traditional Chinese medicine (TCM) has provided an experience-based but subjective diagnosis system for LDH, demanding objective evidence ...
Bermúdez Celina C Grupo de Espectroscopia Molecular (GEM), Edificio Quifima Laboratorios de Espectroscopia y Bioespectroscopia, Parque Científico UVa, Universidad de Valladolid, 47011 Valladolid (Spain) - - 2014
Histidine is an important natural amino acid, involved in many relevant biological processes, which, because of its physical properties, proved difficult to characterize experimentally in its neutral form. In this work, neutral histidine has been generated in the gas phase by laser ablation of solid samples and its Nε H ...
Yu Xiang X Department of Chemistry, Renmin University of China, Beijing 100872 (P. R. - - 2014
Polydopamine (PDA) generated by the oxidative self-polymerization of dopamine shows great potential for surface modification. Observed PDA nanostructures are nanoparticles and thin films. The formation mechanism of PDA is still unclear; thus, the manipulation of PDA nanostructures is a big challenge. In this study, we first demonstrated that folic acid ...
Gajzlerska Wanda W Medical University of Warsaw, Department of Drug Technology & Pharmaceutical Biotechnology, Banacha 1a, Warszawa 02-097, Poland. Electronic address: - - 2014
Tacrolimus, a 23-membered polyketide macrolide, is isolated as a metabolite from the whole fermentation broth of Streptomyces species. This potent immunosuppressive calcineurin inhibitor has been widely used in various fields of medicine, including transplantology, dermatology and pharmacotherapy of autoimmune diseases. The current study was focused on optimisation of tacrolimus biosynthesis ...
Giuffrida Alessandro A Institute of Biostructure and Bioimaging, National Research Council (CNR), via P. Gaifami 18, 95126 Catania, Italy. Electronic address: - - 2014
This review highlights recent progresses in the chiral recognition and separation of amino acid enantiomers obtained by capillary electromigration techniques, using different chiral selectors and especially cyclodextrins, covering the literature published from January 2010 to March 2014. Sections are dedicated to the use of derivatization reagents and to the possibility ...
Ostergaard Jesper J Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark. Electronic address: - - 2014
Variable dissolution from sodium salts of drugs containing a carboxylic acid group after passing the acidic environment of the stomach may affect oral bioavailability. The aim of the present proof of concept study was to investigate pH effects in relation to the dissolution of sodium naproxenate in 0.01M hydrochloric acid. ...
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