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Results 551 - 600 of 2880
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Wang Hualei - - 2013
ABSTRACT: BACKGROUND: A nitrilase-mediated pathway has significant advantages in the production of optically pure (R)-(-)-mandelic acid. However, unwanted byproduct, low enantioselectivity, and specific activity reduce its value in practical applications. An ideal nitrilase that can efficiently hydrolyze mandelonitrile to optically pure (R)-(-)-mandelic acid without the unwanted byproduct is needed. RESULTS: ...
Kwon Eilhann - - 2013
The concept of Waste-to-Energy (WtE) with regards to the utilisation of byproducts from the bioethanol industry (e.g., distiller's dried grain with solubles: DDGS) was employed to enhance the renewability of biodiesel, which would be an initiative stage of a biorefinery due to the conjunction between bioethanol and biodiesel. For example, ...
Aliani Michel M Department of Human Nutritional Sciences, University of Manitoba Winnipeg, Manitoba, Canada, R3T - - 2013
Ingredients such as ascorbic acid used to preserve redness of the raw meat, and carnosine and ribose used for flavor improvement have been incorporated into minced meats to increase consumer acceptance. The objective of this study was to investigate the possible synergistic effect of ascorbic acid, carnosine, and ribose on ...
White James David - - 2013
The tripeptide (S)-valinyl-(S)-m-hydroxyphenylalanyl-(3S)-piperazate common to immunosupressants sanglifehrins A-D was synthesized from the constituent amino acid residues in nine steps and 42% overall yield via a sequence that began from m-hydroxybenzaldehyde. A key construction was the installation of (S) absolute configuration in m-hydroxyphenylalanine using asymmetric phase-transfer catalysis in the presence of ...
Liu Tiantian - - 2013
A solid acid catalyst, prepared by sulfonating carbonized corn straw, was proved to be an efficient and environmental benign catalyst for the esterification of oleic acid and methanol. Various synthetic parameters, such as carbonization temperature and time were systematically examined. It was found that the catalyst exhibited the highest acid ...
Liang Yi - - 2013
This work was to utilize acetic acid contained in bio-oil for growth and lipid production of the microalga Chlamydomonas reinhardtii. The acetic acid-rich bio-oil fraction derived from fast pyrolysis of softwood contained 26% (w/w) acetic acid, formic acid, methanol, furfural, acetol, and phenolics as identified compounds, and 13% (w/w) unidentified ...
Aggarwal Anupama - - 2013
The electrochemical behavior of dopamine was examined under redox cycling conditions in the presence and absence of a high concentration of the interferent ascorbic acid at a coplanar, microelectrode array where the area of the generator electrodes was larger than that of the collector electrodes. Redox cycling converts a redox ...
An Meiling - - 2013
Chlamydomonas sp. ICE-L which can thrive in extreme environments of the Antarctic is a major biomass producer. The FAD genes in Chlamydomonas sp. ICE-L were obtained and sequence alignment showed that these genes are homologous to known FADs with conserved histidine motifs. In this study, we analyzed the transcription of ...
Lee Songyi - - 2013
A new polydiacetylene oxyphenylboronic acid (PDA-OPBA-1) bearing group was synthesized and showed diverse colorimetric changes, such as yellow, orange, and red, upon the addition of cationic surfactants at pH 7.4. On the other hand, anionic surfactants and simple ammonium salts did not show any color change. Specifically, color changes to ...
Han Qian - - 2013
A chiral interface has been designed for specific recognition of carboxylic acids using multilayer architectures of β-cyclodextrin (β-CD) and methylene blue/reduce-graphene (MB@rGO) on glassy carbon electrodes. The advantages of β-CD as a chiral selector and MB@rGO composite as an electrochemical indicator were perfectly presented in this novel interface. It displayed ...
Ragheb Ragy R T - - 2013
PURPOSE: Combined therapeutic and diagnostic agents, "theranostics" are emerging valuable tools for noninvasive imaging and drug delivery. Here, we report on a solid biodegradable multifunctional nanoparticle that combines both features. METHODS: Poly(lactide-co-glycolide) nanoparticles were engineered to confine superparamagnetic iron oxide contrast for magnetic resonance imaging while enabling controlled drug delivery ...
Lata Suman - - 2013
An improved D-amino acid biosensor was constructed based on covalent immobilization of D-amino acid oxidase onto carboxylated mutliwalled carbon nanotubes/copper nanoparticles/polyalinine hybrid film electrodeposited on Au electrode. The biosensor exhibited optimum response within 2s at pH 8.0 and 30°C, when polarized at 0.09V. There was a linear relationship between biosensor ...
Mat Hadzir Nursyamsyila N Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. - - 2013
Fatty acid esters are long-chain esters, produced from the reaction of fatty acids and alcohols. They possess potential applications in cosmetic and pharmaceutical formulations due to their excellent wetting behaviour at interfaces and a non-greasy feeling when applied on the skin surfaces. This preliminary work was carried out to construct ...
Ma Bao-Di - - 2013
A novel esterase, rPPE01, from Pseudomonas putida ECU1011 was heterologously expressed in Escherichia coli and identified for enzymatic resolution of hydroxy acids via O-deacetylation. α-Acetoxy carboxylates were converted with approximately 50% yield and excellent enantioselectivity (E>200) at a substrate concentration of 100mM. The half-lives of rPPE01 were 14days at 50°C ...
Yang Wandian - - 2013
Furfural is one of the most promising platform chemicals derived from biomass. In this study, response surface methodology (RSM) was utilized to determine four important parameters including reaction temperature (170-210°C), formic acid concentration (5-25g/L), o-nitrotoluene volume percentage (20-80vt.%), and residence time (40-200min). The maximum furfural yield of 74% and selectivity ...
Maier Michael P - - 2013
Assessing the environmental fate of chiral micropollutants such as herbicides is challenging. The complexity of aquatic systems often makes it difficult to obtain hydraulic mass balances, which is a prerequisite when assessing degradation based on concentration data. Elegant alternatives are concentration-independent approaches like compound-specific isotope analysis or enantiospecific concentration analysis. ...
Song Jae Yang - - 2013
Heterologous expression of a putative K+/H+ antiporter of Streptomyces coelicolor A3(2) (designated as sha4) in E. coli and Streptomyces hygroscopicus JCM4427 showed enhanced tolerance to K+ stress, acidic-pH shock, and/or geldanamycin production under K+ stress. In a series of K+ extrusion experiments with sha4-carrying E. coli deficient in the K+/H+ ...
Hodgson P A - - 2013
Sharp metal tips have many uses, including in scanning probe microscopy. Silver is a particularly interesting metal for plasmonic enhancement, e.g., in tip-enhanced Raman spectroscopy, however few methods for the production of silver tips have been explored. A simple and reliable one step dc electrochemical method for the production of ...
Zoué Lessoy T - - 2013
The search for new sources of oil with improved characteristics has focused our attention on the characterisation of Irvingia gabonensis seed kernel oil. Physicochemical analysis have revealed the following assets: refractive index (1.42 ± 0.00), free fatty acids (2.3 ± 0.8%), peroxide value (3.33 ± 0.57 meq O(2)/kg), iodine value (32.43 ± 1.22 g I(2)/100 g), saponification value (233.75 ± 2.60 mg KOH/g), ...
Ballesta-Claver J - - 2013
A new method for uric acid (UA) determination based on the quenching of the cathodic ECL of the tris(2,2-bipyridine)ruthenium(II)-uricase system is described. The biosensor is based on a double-layer design containing first tris(2,2-bipyridine)ruthenium(II) (Ru(bpy)3(2+)) electrochemically immobilized on graphite screen-printed cells and uricase in chitosan as a second layer. The uric ...
Park J H JH Swine Science and Technology Center, Gyeongnam National University of Science and Technology, Jinju 660-758, - - 2013
Influence of Achyranthes japonica Nakai Extract (AJNE) on properties of pork sausages were studied in the present investigation. AJNE was added to sausages alone or in combination with ascorbic acid to obtain a comparative analysis on properties of control and ascorbic acid added-sausages. Results showed that addition of 0.05% AJNE ...
Ranalli F - - 2013
This work reports on the composition and bionutritional value of organic virgin olive oil from the Nocellara del Belice variety, one cultivated in the olive areas of the Sicily region, Italy. Destoned oils obtained by processing olives with a destoning-based procedure were compared with conventional oils. This innovative technique, consisting ...
Freitas Cláudia - - 2013
The use of lignocellulosic materials as substrate for bioethanol production is considered a cost-effective approach to make the biofuel production process economically sustainable. However, lignocellulosic hydrolysis releases toxic compounds such as weak acids which inhibit microorganism growth and ethanol production. In order to understand the physiological response of Saccharomyces carlsbergensis ...
Lee Choong Hwan - - 2013
Background/Aims: Metabolomics is a powerful tool for measuring low-molecular-weight metabolites in an organism at a specified time under specific environmental conditions. The aim of this study was to determine the usefulness of metabolomics in identifying the metabolites in stool-fat-positive specimens, and to establish whether the results could be used to ...
Chih Yi-Kai - - 2013
An 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS)-immobilized carbon nanotube (CNT) electrode was used to simultaneously detect dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) with differential pulse voltammetry. When ABTS was immobilized onto the CNT electrode in the presence of DA, UA and 100μM AA, the sensitivity to ...
Tang Xiaoling - - 2013
Microbial production of biofuel has attracted significant attention in recent years. The fatty acids are important precursors for the production of fuels and chemicals, and its biosynthesis is initiated by the conversion of acetyl-CoA to malonyl-CoA which requires acetyl-CoA as key substrate. Herein, the yeast Saccharomyces cerevisiae was proposed to ...
Cao Feng - - 2013
In our previous studies, ethylene glycol-linked amino acid diester prodrugs of Oleanolic Acid (OA), a Biopharmaceutics Classification System (BCS) Class Ⅳ drug, designed to target peptide transporter 1 (PepT1) have been synthesized and evaluated. Unlike ethylene glycol, propylene glycol is of very low toxicity in vivo. In this study, propylene ...
Labroo Pratima - - 2013
We present an electrical biosensing of 5-aminosalicylic acid (5-ASA) based on a peroxidase-immobilized graphene sensor on a microfluidic paper. The sensor shows a sensitive detection range from 0.5 to 20 μM and a total measuring time of 2 min with a simple fabrication procedure.
Lewis Susannah S SS Department of Psychology & Neuroscience, University of Colorado at Boulder, Boulder, CO 80309-0345, - - 2013
We have previously observed that the non-opioid morphine metabolite, morphine-3-glucuronide, enhances pain via a toll-like receptor 4 (TLR4) dependent mechanism. The present studies were undertaken to determine whether TLR4-dependent pain enhancement generalizes to other classes of glucuronide metabolites. In silico modeling predicted that glucuronic acid alone and ethyl glucuronide, a ...
Jingyan Shi - - 2013
The thermal behavior of dry solid ascorbic acid in nitrogen atmosphere in the temperature range of 25-800°C was investigated by TG-FTIR. During the thermal decomposition process, five evolved gaseous species, including H(2)O, CO(2), CO, CH(4) and HCOOH, were identified and monitored, in which HCOOH was detected for the first time. ...
Ghasemi Ebrahim - - 2013
In this study, changes in the chemical composition, pH, cell wall and degradability of ensiled rice straw were investigated when treated with alkali, acid, oxidant agents (1-11 %, w/w) and a combination of an oxidant with either an alkali (ALHP) or an acid (ACHP). The findings of the study revealed that ...
Wang Zhihua - - 2013
In this work, a universal chemiluminescence (CL) flow-through device suitable for various CL resonance energy transfer (CRET) systems has been successfully fabricated. Highly efficient CRET in solid-state photoactive organic molecules can be achieved by assembling them on the surface of layered double hydroxides (LDHs). We attribute these observations to the ...
Li Weiping - - 2013
Dual-signal amplification strategy for ultrasensitive electrochemiluminescence (ECL) multiplexed immunoassay on microfluidic paper-based analytical devices (μ-PADs) was demonstrated. This dual-signal amplification technique was achieved by employing graphene oxide-chitosan/gold nanoparticles (GCA) immunosensing platform and [4,4'-(2,5-dimethoxy-1,4-phenylene)bis(ethyne-2,1-diyl) dibenzoic acid] (P-acid) functionalized nanoporous silver (P-acid/NPS) signal amplification label. For further low-cost and disposable applications, battery-triggered ...
Musharraf Syed Ghulam - - 2013
ABSTRACT: BACKGROUND: Glycyrrhetic acid, a pentacyclic triterpenoid, possesses a broad range of pharmacological activities and serves as template to synthesize many bioactive drugs. This paper describes a simple, accurate, and sensitive stability-indicating TLC densitometric method for the determination of glycyrrhetic acid and its degradation product as per the ICH guidelines. ...
Galván Ismael - - 2013
Abstract Higher vertebrates synthesize two forms of melanin: eumelanin and pheomelanin. While the adaptive functions of eumelanin are diverse, those of pheomelanin, which is phototoxic and whose production consumes a key intracellular antioxidant (glutathione), are not clear apart from being involved in color patterns that confer concealment. The factors that ...
Zeng Huahui - - 2013
[(99m)Tc(CO)(3)](+)-6-[N-(2-dipicolyl)amino]hexanoic acid () and [(99m)Tc(CO)(3)](+)-11-[N-(2-dipicolyl)amino]undecanoic acid () were prepared by incorporating [(99m)Tc-(CO)(3)](+) into 6-[N-(2-dipicolyl)amino]hexanoic acid and 11-[N-(2-dipicolyl)amino]undecanoic acid, respectively. The overall radiochemical yield of and was from 79.7% to 91.3% and radiochemical purity after HPLC purification was more than 94%. The resulting complexes were found to be chemically stable when ...
Yang Zhiyong - - 2013
Aryl ketones were synthesized via Pd-catalyzed decarboxylative coupling between O-methyl oximes and phenylglyoxylic acids using (NH(4))(2)S(2)O(8) as the oxidant.
Pandey Lila B - - 2013
Interaction of lactic acid with various sizes of magnesium oxide clusters (MgO)(x) (x = 2, 4, 6, 8, 9, 12, 15, 16, 18) is investigated. Density functional theory with the PBE functional and a polarized double-ζ basis set is employed to optimize the structures. For MgO dimer, optimizations are also ...
Su Chean-Cheng - - 2013
The oppositely oriented lamellae in ridge and valley bands of ring-banded spherulites in biodegradable poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) interacting with amorphous poly(vinyl acetate) (PVAc) were examined using polarized-light optical, scanning electron, and atomic-force microscopy techniques (POM, SEM, AFM). Solvent-etching and fracturing were utilized for probing the interior morphology of the ...
Zhang Guo-Qing - - 2013
A monomeric acid phosphatase (ACP) with a molecular mass of 72.5 kDa was purified from fresh fruiting bodies of cultured Schizophyllum commune mushroom. The isolation procedure entailed ion exchange chromatography on DEAE-cellulose, CM-cellulose, and Q-sepharose, and gel filtration by fast protein liquid chromatography on Superdex 75. It demonstrated a unique N-terminal ...
Davidovic Sonja - - 2013
Physicochemical, sensory and health related characteristics of peach wine produced from Redhaven variety and selected white wines produced from various grape varieties were determined and compared. The alcohol content, titratable acidity and total extract of peach wine was significantly lower compared with white wines, while its pH value was higher. ...
Tóth L - - 2013
Acetylsalicylic acid (aspirin) suppresses the generation of prostaglandin H2, which is the precursor of thromboxane A2. Aspirin acts as an acetylating agent in which its acetyl group is covalently attached to a serine residue (S530) in the active site of the cyclooxygenase-1 enzyme. The exact reaction mechanism has not been ...
Mó Otilia - - 2013
The structure and electronic properties of the complexes formed by the interaction of imidazole and pyrazole with different BeXH(BeX(2)) (X = H, Me, F, Cl) derivatives have been investigated via B3LYP/6-311+G(3df,2p)//B3LYP/6-31+G(d,p) calculations. The formation of these azole:BeXH(BeX(2)) complexes is accompanied by a dramatic enhancement of the intrinsic acidity of the ...
Hsu Hung-Te - - 2013
A novel technology of photoelectrocatalysis (PEC) combining with cationic exchange membrane (CEM) was proposed for simultaneous reduction of chromium(VI) and oxidization of EDTA. The application of CEM was used to enhance the efficiency for prevention of the re-oxidation of reduced chromium with the electron-hole pairs. In this study, effects of ...
Roder Friedrich - - 2013
We have established an approach for the spatial control of lipid phase separation in tethered polymer-supported membranes (PSM), which were obtained by vesicle fusion on a PEG polymer brush functionalized with fatty acid moieties. Phase separation of ternary lipid mixtures (DOPC/SM/cholesterol) into liquid disordered (ld) and liquid ordered (lo) phases ...
Yu Shiji - - 2013
A Ni/silicon microchannel plate (Ni/Si MCP) electrode modified with poly(3,4-ethylenedioxythiophene) (PEDOT) was successfully fabricated. The analytical performance of prepared electrode for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA) was investigated by using cyclic voltammetry and differential pulse voltammetry (DPV). The sensitivities for AA, DA ...
Wang Fenfen - - 2013
The catalytic dehydration of fructose to 5-hydroxymethylfurfural (HMF) in DMSO was performed over Nb(2)O(5) derived from calcination of niobic acid at various temperatures (300-700°C). The catalysts were characterized by powder X-ray diffraction, N(2) physical adsorption, temperature-programed desorption of NH(3), n-butylamine titration using Hammett indicators, infrared spectroscopy of adsorbed pyridine, and ...
Suzuki Yaeko - - 2013
We determined the δD values of the total fatty acids of Japanese rice to test the hypothesis that there is a wide variation in the hydrogen isotopic composition (δD) of the total fatty acids of Japanese rice sourced from different growth areas in Japan and to distinguish the minor differences ...
Esclapez M D - - 2013
The electrochemical degradation of trichloroacetic acid (TCAA) in water has been analysed through voltammetric studies with a rotating disc electrode and controlled-potential bulk electrolyses. The influence of the mass-transport conditions and initial concentration of TCAA for titanium, stainless steel and carbon electrodes has been studied. It is shown that the ...
McNamara Robert K - - 2013
Deficiency in long-chain omega-3 (LCn - 3) fatty acids, eicosapentaenoic acid (EPA, 20:5n - 3) and docosahexaenoic acid (DHA, 22:6n - 3), has been implicated in the pathoetiology of cardiovascular disease, a primary cause of excess premature mortality in patients with schizophrenia (SZ). In the present study, we determined erythrocyte ...
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