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Otamonga Jean-Paul JP Department of Chemical and Biological Sciences, University of Huddersfield, - - 2014
In order to study the mechanism of the enhancement of solution chemiluminescence, the kinetics of the decay of the oxidant and the chemiluminescence emission were followed for oxidations by permanganate, manganese dioxide sol and Mn(3+) (aq) of glyoxylic acid, using stopped-flow spectrophotometry. Results are reported for the glyoxylic acid oxidized ...
Miura Yukari - - 2014
The effect of polyphenols and related phenolic compounds on the reduction of metmyoglobin (MetMb) to oxymyoglobin (MbO2), in the presence of cysteine, was investigated. Caffeic acid, dihydrocaffeic acid, and hydroxtyrosol (600 µmol/L) did not show any reducing activity individually. However, their highly potent activity in the reduction of MetMb to ...
Liu Lingyi L Dept. of Food Science and Nutrition, School of Biosystems Engineering and Food Science, Zhejiang Univ, Hangzhou, 310058, Zhejiang, PR - - 2014
Antioxidant of bamboo leaves (AOB) is a novel natural food antioxidant approved in China since 2004. Natural phenolics contained in the current AOB are usually polyhydroxy derivatives exhibiting hydrophilic character, which has been marked as water-soluble AOB (AOB-w). In order to broaden the application fields, oil-soluble AOB (cAOB-o) was obtained ...
Jang Se-Eun - - 2014
Ursolic acid, which was isolated from an ethanol extract of Cornus officinalis fruit, potently inhibited NF-κB activation in lipopolysaccharide (LPS)-stimulated peritoneal macrophages. Therefore, we investigated anti-inflammatory mechanism of ursolic acid in LPS-stimulated macrophages and colitic mice. Ursolic acid inhibited phosphorylation of IRAK1, TAK1, IKKβ and IκBα, as well as activation ...
von der Haar Daniela D Department of Process Engineering, Process Development for Plant Raw Materials, Fraunhofer Institute for Process Engineering and Packaging IVV, Giggenhauser Str. 35, 85354, Freising, Germany, - - 2014
Different immobilized lipases were screened for their ability to esterify free fatty acids (FFA) with monoacylglycerol (MAG) as acyl-group acceptor. A lipase from Rhizomucor miehei (Lipozyme RMIM) was the most suitable for lipase-catalyzed de-acidification-a promising alternative to conventional neutralization. A reduction of the FFA content to 0.6 % (w/w) was achieved ...
Wang Limin L CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, - - 2014
Bacillus coagulans 2-6 is an excellent producer of optically pure l-lactic acid. However, little is known about the synthesis mechanism for high optical purity of l-lactic acid produced by this strain. Three enzymes responsible for lactic acid production, l-nLDH (encoded by ldhL), d-nLDH (encoded by ldhD), and glycolate oxidase (encoded ...
Dohare Preeti P Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, - - 2014
The contribution of oxidative stress to ischemic brain damage is well established. Nevertheless, for unknown reasons, several clinically tested antioxidant therapies failed to show benefits in human stroke. Based on our previous in vitro work, we hypothesized that the neuroprotective potency of antioxidants is related to their ability to limit ...
Zanfini Assunta A Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Viale Bracci, 53100, Siena, - - 2014
Globoid cell leukodystrophy or Krabbe disease is an inherited autosomal recessive disorder caused by mutations in the galactosylceramidase gene. The objective of the study was to present information about the fatty acid (FA) composition of the brain and serum of twitcher mice, a mouse model of Krabbe disease, compared to ...
Mellmer Max A MA Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706 - - 2014
Reaction kinetics were studied to quantify the effects of polar aprotic organic solvents on the acid-catalyzed conversion of xylose into furfural. A solvent of particular importance is γ-valerolactone (GVL), which leads to significant increases in reaction rates compared to water in addition to increased product selectivity. GVL has similar effects ...
Chen Hongxing H School of Food Science and Technology, Jiangnan Univ, Wuxi 214122, China; Yancheng Inst. of Technology, Yancheng, 224051, - - 2014
Ammonia caramels are among the most widely used colorant additives in the food industry. They are commonly prepared through the Maillard reaction and caramelization of mixtures of reducing sugars with ammonia or ammonium salts. Antioxidants are known to inhibit acrylamide formation during the Maillard reaction, and they may affect the ...
Chen Xg X Animal Science and Technology School, Henan University of Science and Technology , Luoyang, 471003 Henan Province , - - 2014
Citric acid is a food additive that is widely used in the food and drink industry. We investigated the effects of citric acid injection on mouse kidney. Forty healthy mice were divided into four groups of 10 including one control group and three citric acid-treated groups. Low dose, middle dose ...
Takahashi Toru - - 2014
In this study, the phenylpropanoid composition and antioxidant activity of identified components in fig (Ficus carica L.) leaves were examined. Known polyphenols rutin, isoschaftoside, isoquercetin, and chlorogenic acid were identified. Furthermore, caffeoylmalic acid (CMA) was the most abundant polyphenol and was identified for the first time. CMA exhibited similar antioxidant ...
Shao Xinxin X Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Ling-Ling Road, Shanghai 200032, - - 2014
A Cu-catalyzed trifluoromethylthiolation of primary and secondary alkylboronic acids with an electrophilic trifluoromethylthiolating reagent is described. Tolerance for a variety of functional groups was observed.
Li Ruihua R Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, No. 27 Shanda South Road, Jinan 250100, Shandong, People's Republic of - - 2014
The objective of this study was to investigate the influence of coagulant dosage and pH on coagulation performance and floc properties using polyaluminum chloride (PAC) and compound bioflocculant (CBF) dual-coagulant in kaolin-humic acid (HA) treatment. Results showed that as PAC dosage rose, comparatively better coagulation efficiencies and floc characteristics were ...
Shih Jennifer J Department of Neuroscience, Tufts University School of Medicine, 136 Harrison Ave, Boston, MA, 02111; Neuroscience Program, Tufts University Sackler School of Biomedical Sciences, 136 Harrison Ave, Boston, MA, - - 2014
Glutamate transport is a critical process in the brain that maintains low extracellular levels of glutamate to allow for efficient neurotransmission and prevent excitotoxicity. Loss of glutamate transport function is implicated in epilepsy, traumatic brain injury, and amyotrophic lateral sclerosis (ALS). It is unclear whether or not glutamate transport can ...
Wu Jun-Yi JY a Department of Mechanical Engineering and Green Energy Materials Center , Far East University , Tainan 744 , - - 2014
Abstract The purpose of this study was to develop a resource recovery procedure for recovering copper and zinc from dust produced by copper smelting furnaces during the manufacturing of copper-alloy wires. The concentrations of copper in copper-containing dust do not meet the regulation standards defined by the Taiwan EPA; therefore, ...
Watanabe Shiro S Department of Nutritional Biochemistry, Institute of Natural Medicines, University of Toyama, Toyama, 930-0194, Japan, - - 2014
Mice were fed a control diet or a diet supplemented with hyodeoxycholic acid, the most abundant bile acid contained in pig bile, for 4 weeks, after which their serum and livers were collected. The contents of total fatty acids of serum and liver cholesteryl esters, and of liver triglycerides, were reduced ...
Vivian Diana D Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, - - 2014
Previously, we developed a trifluorinated bile acid, CA-lys-TFA, with the objective of noninvasively assessing bile acid transport in vivo using (19) F magnetic resonance imaging (MRI). CA-lys-TFA was successfully imaged in the mouse gallbladder, but was susceptible to deconjugation in vitro by choloylglycine hydrolase (CGH), a bacterial bile acid deconjugating enzyme ...
Mikulic-Petkovsek Maja M University of Ljubljana, Biotechnical Faculty, Agronomy Department, Chair for Fruit, Wine and Vegetable Growing, Jamnikarjeva 101, SI-1000, Ljubljana, - - 2014
As a part of the ongoing interest in nutritional and nutraceutical properties of locally produced fruits, the aim of the article was to determine sugars, organic acids, polyphenols and antioxidant capacity of wild bilberries grown in Slovenia. Primary and secondary metabolite composition of bilberry fruit was compared among six phyto-climatic ...
Liu Ying Y School of Environment and Energy, Peking University-Shenzhen Graduate School, Shenzhen, 518055, - - 2014
Thraustochytrids have recently emerged as a promising source for docosahexaenoic acid (DHA) production due to their high growth rate and oil content. In this study, two thraustochytrid isolates, Aurantiochytrium sp. PKU#SW7 and Thraustochytriidae sp. PKU#Mn16 were used for DHA production. Following growth parameters were optimized to maximize DHA production: temperature, ...
Socha Robert R a Department of Analysis and Evaluation of Food Quality , Faculty of Food Technology, University of Agriculture in Krakow , Balicka Street 122, 30-19 Krakow , - - 2014
The aim of this work was to determine phenolic acid and flavonoid contents, as well as antioxidant properties of propolis from different regions of Poland. Total phenolic content of propolis samples ranged from 150.05 to 197.14 mg/g GAE, while total flavonoid content was 35.64-62.04 mg/g QE. The dominant phenolic acid was p-coumaric ...
Li He H Department of Biotechnology and Chemical Technology, School of Chemical Technology, Aalto University, P.O. Box 16100, 00076, Aalto, - - 2014
Thermopolyspora flexuosa GH11 xylanase (XYN11A) shows optimal activity at pH 6-7 and 75-80 °C. We studied how mutation to aspartic acid (N46D and V48D) in the vicinity of the catalytic acid/base affects the pH activity of highly thermophilic GH11 xylanase. Both mutations shifted the pH activity profile towards acidic pH. ...
Zhong Min M College of Chemistry and Materials Science, Anhui Key Laboratory of Chemo-Biosensing, Anhui Key Laboratory of Functional Molecular Solids, Anhui Normal University, Wuhu 241000, PR - - 2014
A molecular imprinting polymer (MIP) based electrochemical sensor was successfully prepared for dopamine (DA) recognition and detection using pyrrole-phenylboronic acid (py-PBA) as a novel electropolymerized monomer. py-PBA could form cyclic boronic ester bond with DA, thus endowing a double recognition capacity of the sensor to DA in the combination of ...
Patil Umesh U KAUST Catalysis Center (KCC), King Abdullah University of Science & Technology, Thuwal 23955-6900, Saudi Arabia. - - 2014
A Zn-exchanged heteropolyacid supported onto silica (Zn-HPW/SiO2) activates methane at 25 °C into Zn-methyl. At higher temperatures and with CH4/O2 or CH4/CO2, it gives methanol and acetic acid respectively.
Barden Anne A University of Western Australia, Australia - - 2014
Background: Resolution of inflammation is an active process involving specialised proresolving mediators (SPM) formed from the n-3 fatty acids. This study examined the effect of n-3 fatty acid supplementation and aspirin on plasma SPM in healthy humans. Study Design: Healthy volunteers (n=21) were supplemented with n-3 fatty acids (2.4g/day) for ...
Tian Shuge S Xinjiang Key Laboratory of Famous Prescription and Science of Formulas, Urumqi, Xinjiang, China / College of TCM, Xinjiang Medical University, Urumqi, Xinjiang, - - 2014
This study aims to determine the phytochemical composition and antioxidant activity of air-dried Cordia dichotoma seeds. Total polyphenolic content was analyzed via the Folin-Ciocalteu method. Total triterpenoid content and amino acids was analyzed colorimetrically. The rosmarinic acid content was examined using high-performance liquid chromatography tandem mass spectrometry. The ethanolic extracts ...
Yoon Jae-Hyun JH Department of Food Science and Technology, Chung-Ang University, 72-1, Nae-ri, Daedeok-myeon, Anseong-si, Gyeonggi-do, 456-756, - - 2014
This study investigated the effects of sodium chloride (NaCl) and various acids, alone or in combination, on Shigella flexneri growth in laboratory medium and cucumber puree. S. flexneri was treated with various acids (acetic, citric, malic, tartaric, propionic, lactic, and phosphoric acid) alone or with 3%, 6%, or 9% NaCl. ...
Sun H H Institute of Dairy Science, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China ; Qilu University of Technology, Jinan, 250353, China - - 2014
An in vitro experiment was conducted to evaluate the effects of Aspergillus oryzae culture (AOC) and 2-hydroxy-4-(methylthio)-butanoic acid (HMB) on rumen fermentation and microbial populations between different roughage sources. Two roughage sources (Chinese wild rye [CWR] vs corn silage [CS]) were assigned in a 2×3 factorial arrangement with HMB (0 ...
Sivaci Aysel A Adiyaman University Department of Biology, Art and Science Faculty Adiyaman - - 2014
In this study, the changes caused by chilling stress on some physiological parameters of pepino (Solanum muricatum Ait.) plant and the effects of ascorbic acid (100 mM) applied exogenously on these changes were examined. For this purpose, the photosynthetic pigments (chlorophyll a, chlorophyll b, total chlorophylls and carotenoids), ascorbic acid, ...
Tsurugizawa T T Institute for Innovation, Ajinomoto Co., Inc., Kawasaki-ku, Kawasaki-shi, - - 2014
The 20 different amino acids, in blood as well as in the brain, are strictly maintained at the same levels throughout the day, regardless of food intake. Gastric vagal afferents only respond to free glutamate and sugars, providing recognition of food intake and initiating digestion. Metabolic control of amino acid ...
Hashemabadi Davood - - 2014
Silver nano-particles (2-5 nm diam.), as antimicrobial agent and boric acid, as ethylene production inhibitor are used for enhancing the quality and vase life of cut flowers. In the present study the effects of a preservative solution containing nano-silver and boric acid on some traits of cut rose (Rosa hybrida ...
Russell Mark H MH DuPont Haskell Centers for Health and Environmental Sciences, E. I. duPont de Nemours and Company, Inc., 1090 Elkton Road, Newark, DE 19711-3507, USA. Electronic address: - - 2014
The toxicokinetics of 6:2 fluorotelomer alcohol (6:2 FTOH) and its terminal perfluorinated and polyfluorinated metabolites (PFBA, PFHxA, PFHpA and 5:3 Acid) have been calculated from laboratory studies of rats and from a biomonitoring study of humans. In vitro studies with mouse, rat and human hepatocytes indicate qualitatively similar metabolic pathways ...
Vlassopoulos A A Human Nutrition, School of Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, G3 8SJ, UK. - - 2014
Background: while antiglycative capacity has been attributed to (poly)phenols, the exact mechanism of action remains unclear. Studies so far are often relying on supra-physiological concentrations and use of non-bioavailable compounds. Methods: to inform the design of a physiologically relevant in vitro study, we carried out a systematic literature review of ...
Laino Carlos Horacio CH Instituto de Biotecnología, Centro de Investigación e Innovación Tecnológica (CENIIT), Universidad Nacional de La Rioja, La Rioja, - - 2014
We previously reported that combined fluoxetine administration at antidepressant doses renders additive antidepressant effects, whereas non-antidepressant doses potentiate the omega-3 fatty acid antidepressant effect. In the present study, we aimed to evaluate putative pharmacokinetic and brain omega-3 fatty acid-related aspects for fluoxetine potentiation of omega-3 fatty acid antidepressant effect in ...
Mansouri Mohammad Taghi MT Department of Pharmacology, School of Medicine, Physiology and Atherosclerosis Research Centers, Ahvaz Jundishapur Univ. of Med. Sciences, Ahvaz, Iran. Electronic address: - - 2014
According to our previous study, ellagic acid has both dose-related central and peripheral antinociceptive effect through the opioidergic and L-arginine-NO-cGMP-ATP sensitive K(+) channel pathways. In the present study, the systemic antinociceptive effects of ellagic acid in animal models of pain, and functional interactions between ellagic acid and morphine in terms ...
Ferdinandusse Sacha S Laboratory Genetic Metabolic Diseases, Departments of Pediatrics and Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands - - 2014
ABCD3 is one of three ATP-binding cassette (ABC) transporters present in the peroxisomal membrane catalyzing ATP-dependent transport of substrates for metabolic pathways localized in peroxisomes. So far the precise function of ABCD3 is not known. Here we report the identification of the first patient with a defect of ABCD3. The ...
Fangueiro Joana F JF CEBIMED, Investigation Centre of Biomedicine, Faculty of Health Sciences, Fernando Pessoa University (UFP-FCS), Rua Carlos da Maia 296, 4200-150 Porto, Portugal; Faculty of Health Sciences, Fernando Pessoa University (UFP-FCS), Rua Carlos da Maia 296, 4200-150 Porto, - - 2014
Epigallocatechin gallate (EGCG) is a green tea catechin with potential health benefits, such as anti-oxidant, anti-carcinogenic and anti-inflammatory effects. In general, EGCG is highly susceptible to degradation, therefore presenting stability problems. The present paper was focused on the study of EGCG stability in HEPES (N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid) medium regarding the pH ...
Hua Xiangdong X Hepatobiliary and Pancreatic Surgery, Liaoning Cancer Hospital and Institute, Shenyang, 110042, - - 2014
Gambogic acid and gambogenic acid are two major bioactive components of Garcinia hanburyi, and play a pivotal role in biologic activity. In this study, a specific and sensitive liquid chromatography-tandem mass spectrometry was developed and validated for simultaneous determination of gambogic acid and gambogenic acid in rat plasma. Chromatographic separation ...
Jiang Zhi-Bo ZB a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , - - 2014
Seven new aromatic acid derivatives (1-7), together with five known analogs, were isolated from the lateral roots of Aconitum carmichaelii. Structures of the new compounds were determined by spectroscopic and chemical methods as 4-methyl ( - )-(R)-hydroxyeucomate (1), 4-butyl ( - )-(R)-hydroxyeucomate (2), 4-butyl-1-methyl (+)-(R)-2-O-(4'-hydroxy-3'-methoxybenzoyl)malate (3), 1-butyl-4-methyl (+)-(R)-2-O-(4'-hydroxy-3'-methoxybenzoyl)malate (4), dimethyl (+)-(R)-2-O-(4'-hydroxy-3'-methoxybenzoyl)malate (5), dimethyl (+)-(R)-2-O-(4'-hydroxybenzoyl)malate ...
Kanĸár R R Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic. - - 2014
Uric acid is the final product of human purine metabolism. It was pointed out that this compound acts as an antioxidant and is able to react with reactive oxygen species forming allantoin. Therefore, the measurement of allantoin levels may be used for the determination of oxidative stress in humans. The ...
Qamar Wajhul W Central Laboratory, Research Center, College of pharmacy, King Saud University, Riyadh, Saudi - - 2014
ABSTRACT Objective: Rat bronchoalveolar lavage fluid (BALF) metabolome can be used to obtain valuable, precise, and accurate information about underlying lung conditions in an experiment. The present study focuses on the evaluation of the lung epithelium metabolome in a rat model using techniques including bronchoalveolar lavage, gas chromatography-mass spectroscopy (GC-MS), ...
Nohara Kenta K Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama - - 2014
The present study investigated simultaneous oxidation of pyruvate and amino acids during H2-evolving growth of hyperthermophilic archaeon Thermococcus kodakarensis. The comparison of mass balance between a cytosolic hydrogenase (HYH)-deficient strain (ΔhyhBGSL) and the parent strain indicated that NADPH generated via H2 uptake by HYH was consumed by reductive amination of ...
Sun Hongnan - - 2014
In this study, effects of boiling, steaming, microwaving, baking and frying on proximate composition, total and individual polyphenol content and antioxidant activity of sweet potato leaves were investigated. An increase of 9.44% in total polyphenol content was observed after steaming, whereas a decrease of 30.51%, 25.70% and 15.73% was noticed ...
Avila-Cisneros Nayeli N Universidad Autónoma Metropolitana-Unidad Iztapalapa, Av. San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, Mexico, 09340, D.F., - - 2014
A naturally immobilized biocatalyst with lipase activity was produced by Thermomyces lanuginosus on solid-state fermentation with perlite as inert support. Maxima lipase activities (22 and 120 U/g of dry matter, using p-nitrophenyl octanoate and trioctanoine, respectively, as substrates) were obtained after 72 h of solid culture, remaining nearly constant up to 120 h. ...
Kundu Chandan C Department of Forest Products and Technology, College of Agriculture and Life Sciences, Chonnam National University, Gwang-ju 500-757, Republic of - - 2014
In order to produce ethanol from yellow poplar, deacetylation was performed using sodium hydroxide (NaOH). Optimal deacetylation conditions were determined by a response surface methodology. The highest acetic acid concentration obtained was 7.06g/L when deacetylation was performed at 60°C for 80min with 0.8% NaOH. Acetic acid was recovered by electrodialysis ...
Tannour-Louet Mounia M Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX - - 2014
Disturbances in amino acid metabolism are increasingly recognized as being associated with, and serving as prognostic markers for, chronic human diseases such as cancer or type 2 diabetes. In the current study, a quantitative metabolomics profiling strategy revealed global impairment in amino acid metabolism in mice deleted for the transcriptional ...
Halicka J J Department of Pathophysiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Bratislava, - - 2014
Transient lower esophageal sphincter relaxation (TLESR) is the major mechanism of gastroesophageal reflux (GER) but the regulation of TLESR by stimuli in the esophagus is incompletely understood. If stimuli in the esophagus can influence TLESR, then such regulation may perpetuate or limit GER. We addressed the hypothesis that acid in ...
Chauhan Nidhi N Department of Biochemistry, M. D. University, Rohtak, 124001, Haryana, - - 2014
A method is described for preparation of uricase nanoparticles (100 nm in size) and their direct immobilization onto the Au electrode. The enzyme electrode along with Ag/AgCl as reference and Pt as auxiliary electrode were connected through potentiostat/galvanostat to construct an amperometric uric acid biosensor. The enzyme electrode was characterized by ...
Kurahashi Toshihiro T Department of Biochemistry and Molecular Biology, Yamagata University School of Medicine, Yamagata, - - 2014
Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, suppresses diabetic complications via a reduction in metabolic intermediates; it also plays a role in ascorbic acid biosynthesis in mice. Because primates cannot synthesize ascorbic acid, a principle role of AKR1A appears to be the reductive detoxification of aldehydes. In ...
Schmeda-Hirschmann Guillermo G Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, 3460000 Talca, Chile. Electronic address: - - 2014
animal oils and fats from the fishes Electrophorus electricus and Potamotrygon motoro, the reptiles Boa constrictor, Chelonoidis denticulata (Geochelone denticulata) and Melanosuchus niger and the riverine dolphin Inia geoffrensis are used as anti-inflammatory agents in the Peruvian Amazon. The aim of the study was to assess the topic anti-inflammatory effect ...
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