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Sun Diankui D Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences , Changchun 130022, People's Republic of - - 2014
The acid-sensitive PEGylated doxorubicin (DOX) with exact chemical structure was designed and prepared as a potential tumor intracellular microenvironment-responsive drug delivery system. First, the insensitive succinic anhydride-functionalized DOX (i.e., SAD) and acid-sensitive cis-aconitic anhydride-modified DOX (i.e., CAD) were synthesized through the ring-opening reaction. Subsequently, the insensitive and acid-sensitive PEGylated DOX ...
Xin Junliang J Research Center for Environmental Pollution Control Technology, Department of Safety and Environmental Engineering, Hunan Institute of Technology, Hengyang, 421002, - - 2014
Cultivars of hot pepper (Capsicum annuum L.) have different abilities to accumulate Cd in their fruits. Previously, we suggested that low-Cd cultivars take up more Cd, but can better prevent the Cd translocation from roots to aerial parts. However, the mechanisms involved in those processes are still unclear. In this ...
Ulset Ann-Sissel T AS NOBIPOL, Department of Biotechnology, Norwegian University of Science and Technology (NTNU) , N-7491 Trondheim, - - 2014
Alginate-based biomaterials and medical devices are commonly subjected to γ-irradiation as a means of sterilization, either in the dry state or the gel (hydrated) state. In this process the alginate chains degrade randomly in a dose-dependent manner, altering alginates' material properties. The addition of free radical scavenging amino acids such ...
Gu Shenghua S State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, Jiangsu Key laboratory of drug design and optimization, China Pharmaceutical University, Nanjing 210009, China. - - 2014
Clinical and animal studies demonstrated that orally administered berberine had a distinct lipid-lowering effect. However, pharmacokinetic studies showed that berberine was poorly absorbed into the body so the levels of berberine in the blood and target tissues were far below the effective concentrations revealed. To probe the underlying mechanism, the ...
Poudel Pramod P Laboratory of Soil Microbiology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, - - 2014
A newly isolated Bacillus sp. MC-07 showed 99.2 % 16S rRNA gene sequence similarity with the Bacillus thermoamylovorans LMG 18084(T). It demonstrated optimum and maximum growth temperatures of 50 and 62 °C, respectively. The ability of MC-07 to produce optically pure L-lactic acid via direct fermentation of starch without enzymatic hydrolysis was investigated ...
Rezg Raja R Laboratoire de Physiologie des Agressions, Département de Biologie, Faculté des Sciences de Tunis, Université El Manar, Tunis, - - 2014
Exposure to pesticides is suspected to cause human health problems. Our study aimed to evaluate preventive effects of caffeic acid (3,4-dihydroxycinnamic acid) in the hypothalamus against malathion-induced neuropeptides gene expression alterations. Malathion at 100 mg/kg was administered intragastrically to rats alone or in combination with caffeic acid at 100 mg/kg during 4 weeks. ...
Collins Gillian - - 2014
Many applications of germanium (Ge) are underpinned by effective oxide removal and surface passivation. This important surface treatment step often requires H-X (X = Cl, Br, I), or HF etchants. Here, we show that aqueous citric acid solutions are effective for the removal of GeOx. The stability of citric acid ...
Miao Wangen W School of Chemistry and Chemical Engineering, Institute of Physical Chemistry, Lingnan Normal University, Development Centre for New Materials Engineering & Technology in Universities of Guangdong, Zhanjiang, 524048 (P. R. China). - - 2014
A new class of L-glutamic gelators, LG12 (CH2 )n COOH, containing different lengths of methylene spacer were synthesized. It was found that the gelation ability of these compounds themselves was very weak. However, when another compound, p-xylylenediamine (XEA), was introduced, the gelation ability was improved greatly. In particular, LG12 (CH2 ...
Zhang Hongdan - - 2014
Acetic acid ethanol-based organosolv pretreatment of sugarcane bagasse were performed to enhance enzymatic hydrolysis. The effect of different parameters (including temperature, reaction time, solvent concentration, and acid catalyst dose) on pretreatment prehydrolyzate and subsequent enzymatic digestibility were determined. During the pretreatment process, 11.83 g xylose based on 100 g raw ...
Musselwhite Nathan N Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United - - 2014
When pure mesoporous silica (MCF-17) was modified with aluminum (Al modified MCF-17), Lewis acid sites were created, but this material was inactive for the catalytic conversion (reforming) of n-hexane to isomers. When colloidally synthesized platinum nanoparticles were loaded onto traditional MCF-17, the catalyst showed very low activity toward isomer production. ...
Meng Zhao-Qing ZQ State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, P. R. China , Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang 222001, P. R. - - 2014
Gout is a metabolic disorder associated with hyperuricemia resulting in the deposition of monosodium urate (MSU) crystals in joints and tissues. Lowering serum uric acid (Sur) levels and anti-inflammation are highly essential in treating gout. Chlorogenic acid (CA), as one of the most abundant polyphenols in the Chinese medicines, has ...
Bogdanovic Elena E Division of Plastic Surgery, Division of General Surgery, Department of Surgery, Department of Immunology, University of Toronto, Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, ON, - - 2014
The endoplasmic reticulum (ER) is an organelle important for protein synthesis and folding, lipid synthesis and Ca(2+) homoeostasis. Consequently, ER stress or dysfunction affects numerous cellular processes and has been implicated as a contributing factor in several pathophysiological conditions. Tunicamycin induces ER stress in various cell types in vitro as ...
Rohilla Raman R Department of Pharmaceutics - - 2014
Abstract Glycyrrhetinic acid-modified chitosan (mGA-suc-CTS) is used as liver-targeted carrier for drug delivery. In this study, nanoparticles were prepared by ionic gelation process, and glycyrrhetinic acid act as the targeting ligand. The structure of the product was confirmed by IR and NMR techniques. The main aim of this study was ...
Wu Enqi E School of Lifescience, Inner Mongolia University for the Nationalities, Tongliao, - - 2014
Capillary electrochromatography was employed for enantioseparation of α-amino acids and their derivatives. (-)-18-Crown-6-2,3,11,12-tetracarboxylic acid bonded on the silica was used as the chiral stationary phase and methanol/Tris-citric acid (20 mM, pH 3.0-4.5) (20:80, v/v) was used as mobile phase. The enantioseparation performance was discussed and structure-chiral separation relationship were tried to ...
Ding Su S Xingjian College of Science and Liberal Arts, Guangxi University, Nanning, 530004, Guangxi, China; Key Laboratory of Ministry of Education for Microbial and Plant Genetic Engineering, Guangxi University, Nanning, 530004, Guangxi, - - 2014
A problem frequently occurring in making some kinds of wines, particularly Vitis quinquangularis Rehd wine, is the presence of malic acid at high concentrations, which is detrimental to the quality of wines. Thus, there is a need of the ways for effectively reducing the malic acid levels in wine. This ...
Ito M M Yakult Central Institute, Yaho 1796, Kunitachi-shi, Tokyo, 186-8650 - - 2014
We investigated the effects of Streptococcus thermophilus YIT 2001, a strain of lactic acid bacteria, on the susceptibility of low-density lipoprotein (LDL) to oxidation and the formation of aortic fatty lesions in hyperlipidemic hamsters. S. thermophilus YIT 2001 had the highest in vitro antioxidative activity against LDL oxidation among the ...
Kaplan Matthew E ME Department of Organismal and Environmental Biology, Christopher Newport University, 1 Avenue of the Arts, Newport News, Virginia, 23606, United - - 2014
The soil environment can affect not only the quantity of crops produced, but also the nutritional quality of crops. We examined the combined effects of belowground cadmium (0, 5, and 15 ppm) and mycorrhizal fungi (presence and absence) on the concentration of five major fatty acids within flax seeds (Linum usitatissimum). ...
Adeyemi Kazeem Dauda KD Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, UPM Serdang, Selangor; Department of Animal Production, University of Ilorin, Ilorin, - - 2014
The study appraised the effects of Carotino oil on in vitro rumen fermentation, gas production, metabolism and apparent biohydrogenation of oleic, linoleic and linolenic acids. Carotino oil was added to a basal diet (50% concentrate and 50% oil palm frond) at the rate of 0, 2, 4, 6 and 8% ...
Häkkinen Silja Alma Kaarina - - 2014
Particulate phase reactions between organic and inorganic compounds may significantly alter aerosol chemical properties, for example, by suppressing particle volatility. Here, chemical processing upon drying of aerosols comprised of organic (acetic, oxalic, succinic or citric) acid/monovalent inorganic salt mixtures was assessed by measuring the evaporation of the organic acid molecules ...
Lescano Caroline Honaiser CH 1 Faculty of Food Engineering, Federal University of Grande Dourados , Dourados, Brazil - - 2014
Abstract Acrocomia aculeata, popularly known as "bocaiuva," is widely acknowledged in culinary and traditional medicines to treat cardiovascular diseases, a combined effect with diuretics that are also used for hypertension. However, there are no scientific data published to support its use as functional food and its ethnopharmacological use. This study ...
Papa Thiago Bueno Ruiz - - 2014
Abstract Astaxanthin when esterified with ferulic acid is better singlet-oxygen quencher with k2 = (1.58 ± 0.1) 10(10) L mol(-1)s(-1) in ethanol at 25°C compared to astaxanthin with k2 = (1.12 ± 0.01) 10(9) L mol(-1)s(-1). The ferulate moiety is in the astaxanthin diester a better radical scavenger than free ...
Wang Dongqiang D Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, Shanghai, - - 2014
The C9-position of quinine was modified by meta- or para-substituted benzo-18-crown-6, and immobilized on 3-mercaptopropyl-modified silica gel through the radical thiol-ene addition reaction. These two chiral stationary phases were evaluated by chiral acids, amino acids and chiral primary amines. The crown ether moiety on the quinine anion-exchanger provided a ligand-exchange ...
Ma Ai-Cui - - 2014
The chemical composition of monogalactosyldiacylglycerols (MGDGs) from brown alga Sargassum horneri and their inhibitory effects on lipid accumulation were investigated in this study. Ten molecular species of MGDGs were identified using NMR, alkaline hydrolysis, GC-FID and HPLC-MS/MS methods. Individual molecular species of MGDGs including (2S)-1-O-myristoyl-2-O-palmitoleoyl-3-O-β-D-galactopyranosyl-sn-glycerol (1), (2S)-1-O-myristoyl-2-O-linoleyl-3-O-β-D-galactopyranosyl-sn-glycerol (3), (2S)-1-O-palmitoyl-2-O-linolenoyl-3-O-β-D-galactopyranosyl-sn-glycerol (5), ...
Hu Wei W Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing 100049, China; Key laboratory of Microbial Resources Exploition and Application, Lanzhou 730000, - - 2014
The properties of the screened mutants for hyper-production of citric acid induced by carbon ((12)C(6+)) ion beams and X-ray irradiation were investigated in our current study. Among these mutants, mutant H4002 screened from (12)C(6+) ion irradiation had a higher yield of citric acid production than the parental strain in a ...
Radwan Michał M From the Department of Gynecology and Reproduction (Dr Radwan, Dr Radwan); "Gameta" Hospital, Rzgów; Department of Environmental Epidemiology (Drs Jurewicz and Hanke, Mr Sobala), Nofer Institute of Occupational Medicine, Lodz; and Department of Toxicology (Dr Wielgomas, Ms Piskunowicz), Medical University of Gdańsk, - - 2014
The aim of this study was to determine whether the environmental exposure to pyrethroids affects semen quality and the level of reproductive hormones in men. The study population consisted of 334 men who attended the infertility clinic for diagnostic purposes and who had normal semen concentration of 15 to 300 ...
Kagan Michael L ML Qualitas Health Ltd, 19 Hartom Street, P.O. Box 45423, Jerusalem 91450, Israel. - - 2014
Long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) exert health benefits which are dependent upon their incorporation into blood, cells and tissues. Plasma and tissue deposition of LC n-3 PUFA from oils extracted from the micro-algae Nannochloropsis oculata and from krill were compared in rats. The algal oil provides eicosapentaenoic ...
Bravo-Ferrada Bárbara Mercedes BM Laboratorio de Microbiología Molecular, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Bernal, - - 2014
The aim of this work was to evaluate the changes due to acclimation to ethanol on the fatty acid composition of three oenological Lactobacillus plantarum strains and their effect on the resistance to ethanol and malic acid consumption (MAC). Lb plantarum UNQLp 133, UNQLp 65.3 and UNQLp 155 were acclimated ...
Kristl Theresa T Division of Chemistry and Bioanalytics, Department of Molecular Biology, University of Salzburg, Salzburg, - - 2014
One pressure and three chemical mobilization strategies have been optimized and tested for two-step capillary isoelectric focusing with UV detection with simultaneous refining of the composition of carrier ampholytes as well as of anodic and cathodic spacers. The comparison of individual mobilization strategies was performed on basis of model proteins ...
Liu Xiaoyan X a Jiangsu Key Laboratory for Biomass-based Energy and Enzyme Technology , Huaiyin Normal University , Huaian , - - 2014
ABSTRACT In this study, crude cellulase produced byTrichoderma reesei Rut-30 was used to hydrolyze the pretreated straw. After the compositions of the hydrolysate of pretreated straw were optimized, it is showed that natural components of pretreated straw without addition of any other components such as (NH4)2SO4, KH2PO4, Mg(2+) were suitable ...
Chen Guanqun G Laboratory for Algae Research and Biotechnology, College of Technology and Innovation, Arizona State University, 7001 E. Williams Field Road, Mesa, AZ, 85212, - - 2014
Astaxanthin, a high-value red ketocarotenoid with strong antioxidant activity, possesses important physiological functions in astaxanthin-producing microalgae. The green microalga Haematococcus pluvialis can accumulate up to 4% of fatty acid-esterified astaxanthin (by dry weight) and has been used as a model species for exploring astaxanthin biosynthesis in unicellular photosynthetic organisms. Although ...
Schultz Alison K - - 2014
Effects of acidity on cloud stability in pasteurized carrot juice were examined over the pH range of 3.5 to 6.2. Cloud sedimentation, particle diameter, and zeta potential were measured at each pH condition to quantify juice cloud stability and clarification during three days of storage. Acidification below pH 4.9 resulted ...
Zhang Jia-En JE Department of Ecology, South China Agricultural University, Wushan Road, Tianhe, Guangzhou, China, - - 2014
Acid rain is still an issue of environmental concerns. This study investigated the impacts of simulated acid rain (SAR) upon earthworm activity from the Latosol (acidic red soil). Laboratory experiment was performed by leaching the soil columns grown with earthworms (Eisenia fetida) at the SAR pH levels ranged from 2.0 ...
Cho Jeong-Yong JY a Department of Food Science & Technology, and Functional Food Research Center , Chonnam National University , Gwangju , Republic of - - 2014
Changes in chemical constituent contents and DPPH radical-scavenging activity in fruits of pear (Pyrus pyrifolia) cultivars during the development were investigated. The fruits of seven cultivars (cv. Niitaka, Chuhwangbae, Wonhwang, Hwangkeumbae, Hwasan, Manpungbae, and Imamuraaki) were collected at 15-day intervals after day 20 of florescence. Vitamins (ascorbic acid and α-tocopherol), ...
Lin Hou-Yu HY Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, - - 2014
Matrix-assisted laser desorption ionization (MALDI) has been widely used in the mass analysis of biomolecules; however, there are a lot of debates about the ionization mechanisms. Previous studies have indicated that S1-S1 annihilation might be a key process in the generation of primary ions. This study investigates S1-S1 annihilation by ...
Proisl Karel K Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlin, 762 72 Zlin, Czech Republic. - - 2014
N-(α-ketoacyl)anthranilic acids reacted with phenylhydrazinium chloride in boiling acetic acid to afford 2-(indol-2-carboxamido)benzoic acids in good to excellent yields and 2-indolyl-3,1-benzoxazin-4-ones as by-products. The formation of the latter products could easily be suppressed by a hydrolytic workup. Alternatively, by increasing the reaction temperature and/or time, 2-indolyl-3,1-benzoxazin-4-ones can be obtained exclusively. ...
Pinu Farhana R FR Centre for Microbial Innovation, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New - - 2014
To investigate the assimilation and production of juice metabolites by Saccharomyces cerevisiae during winemaking, we compared the metabolite profiles of 63 Sauvignon Blanc (SB) grape juices collected over five harvesting seasons from different locations of New Zealand before and after fermentation by the commercial wine yeast strain EC1118 at 15 ...
Mu Shuhua S Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, - - 2014
Background: Melatonin has shown a protective effect against various oxidative damages in the nervous system. Our previous studies have also confirmed its effect on behavioral dysfunction of experimental rats and injury of striatal interneurons induced by 3-nitropropionic acid. The present study aimed to further determine the effect of melatonin on ...
Scandiani María M MM Centro de Referencia de Micología (CEREMIC), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina mechu.scandiani@gmail.com - - 2014
Soybean germplasm exhibits various levels of resistance to Fusarium tucumaniae, the main causal agent of sudden death syndrome (SDS) of soybean in Argentina. In this study, two soybean genotypes, one susceptible (NA 4613) and one partially resistant (DM 4670) to SDS infection, were inoculated with F. tucumaniae. Disease symptoms were ...
Herrmann Sven S Institut für Anorganische Chemie I, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm (Germany) http://www.strebgroup.net; Previous address: Anorganische Chemie II, Friedrich-Alexander-Universität Erlangen-Nürnberg, Egerlandstrasse 1, 91058 Erlangen - - 2014
Corrosion is a global problem for any metallic structure or material. Herein we show how metals can easily be protected against acid corrosion using hydrophobic polyoxometalate-based ionic liquids (POM-ILs). Copper metal disks were coated with room-temperature POM-ILs composed of transition-metal functionalized Keggin anions [SiW11 O39 TM(H2 O)](n-) (TM=Cu(II) , Fe(III) ...
Verma K C KC Lovely Professional University, Ludhiana-Jalandhar G.T. Road, Phagwara (Punjab), 144401, India, - - 2014
Depleting reserves of fossil fuel and increasing effects of environmental pollution from petrochemicals demands eco-friendly alternative fuel sources. Jatropha curcas oil, an inedible vegetable oil, can be a substitute feedstock for traditional food crops in the production of environment-friendly and renewable fuel. Jatropha oil is looked up in terms of ...
Mounayar Rana R 1 CNRS, UMR6265, UMR Centre des Sciences du Goût et de l'Alimentation , Dijon, France - - 2014
Abstract Saliva has different functions in the mouth and is involved, for example, in taste perception. Saliva composition can also be modified rapidly by taste stimulation. It remains unclear, however, whether the perceived intensity of a tastant may modulate this response. Based on increasing evidence that fat can be perceived ...
Zimmermann Sarah C SC Department of Neurology and Brain Science Institute, Johns Hopkins University , Baltimore, Maryland 21205, United - - 2014
Representative d-amino acid oxidase (DAAO) inhibitors were subjected to in vitro liver microsomal stability tests in the absence or presence of uridine diphosphate glucuronic acid (UDPGA). While carboxylate-based DAAO inhibitors displayed little glucuronidation, most DAAO inhibitors containing α-hydroxycarbonyl moiety exhibited nearly complete glucuronidation within 30 min. The one exception was ...
Akoz Enise E Department of Chemistry, Selcuk University, 42031, Konya, - - 2014
Sol-gel encapsulation is a simple but powerful method to enhance the enantioselectivity of lipase-catalyzed transformations in an isooctane/aqueous buffer solution. Candida rugosa lipase was encapsulated according to a sol-gel procedure in the presence and absence of calix[4]arene hydrazine or carboxylic acid derivatives with Fe3O4 magnetic nanoparticles as an additive. The ...
Patel Disha D DD Lab#302B, BRD School of Biosciences, Sardar Patel University, Sardar Patel Maidan, Vadtal Road, Post Box No. 39, Vallabh Vidhyanagar, Gujarat, 388120, - - 2014
Lipoxygenase oxidizes linoleic acid into hydroperoxy octadecadienoic acid (HPOD), which is important in food and flavour industries for production of bread and flavouring compounds. As Lasiodiplodia theobromae is an unexplored, good source of lipoxygenase, it was purified from it by size-exclusion (Sephadex G100) and ion-exchange (DEAE-cellulose) chromatography and characterized. Upon ...
Govindarajan Ramprakash R Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, 55455, - - 2014
The objectives of this study were to measure the apparent surface acidity of common excipients and to correlate the acidity with the chemical stability of an acid-sensitive active pharmaceutical ingredient (API) in binary API-excipient powder mixtures. The acidity of 26 solid excipients was determined by two methods, (i) by measuring ...
Lynch Kevin K Department of Chemistry, Elon University, Elon, North Carolina, USA. - - 2014
Two different and complementary computational methods were used to determine the contributions by inductive/field effects and by electron-delocalization effects toward the enhancement of the gas-phase deprotonation enthalpy of sulfuric acid over ethanol. Our alkylogue extrapolation method employed density functional theory calculations to determine the deprotonation enthalpy of the alkylogues of ...
Franco Federico F Department of Chemistry, via P. Giuria 7, 10125 Torino, Italy. roberto.gobetto@unito.it - - 2014
The effect of a local proton source on the activity of a bromotricarbonyl Mn redox catalyst for CO2 reduction has been investigated. The electrochemical behaviour of the novel complex [fac-Mn(dhbpy)(CO)3Br] (dhbpy = 4-phenyl-6-(1,3-dihydroxybenzen-2-yl) 2,2'-bipyridine), containing two acidic OH groups in the proximity of the metal centre, under a CO2 atmosphere ...
Heemskerk Mattijs M MM Leiden University Medical Center, Netherlands - - 2014
Prolonged niacin treatment elicits beneficial effects on the plasma lipid and lipoprotein profile that are associated with a protective cardiovascular disease (CVD) risk profile. Short term niacin treatment inhibits non-esterified fatty acid (NEFA) release from adipocytes and stimulates prostaglandin release from skin Langerhans cells, but the acute effects diminish upon ...
Chen Zhi-Yao ZY College of Light Industry and Food Science, South China University of Technology, Guangzhou, 510640, China; Sericulture and Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510610, - - 2014
Two kinds of soy sauces were prepared with A. oryzae koji (SSAO) and mixed koji (SSAOM, A. oryzae mouldstarter: Monascus purpureus mouldstarter = 1:2, w/w) respectively. The effects of mixed koji on the essential indices, oxygen radical absorption capacity, color indices, free amino acids and volatile compounds of soy sauce have been ...
Barassi Giancarlo M GM School of Chemical and Physical Sciences, Victoria University of Wellington, New Zealand. giancarlobarassi@gmail.com martin.klimsa@web.de aoc@gmx.li - - 2014
The acid plant 'blow-down' (also called weak acid) produced at El Teniente mine in Chile was characterized. This liquid waste (tailing) is generated during the cooling and cleaning of the smelter gas prior to the production of sulfuric acid. The weak acid was composed of a liquid and a solid ...
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