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Tannour-Louet Mounia M Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX - - 2014
Disturbances in amino acid metabolism are increasingly recognized as being associated with, and serving as prognostic markers for, chronic human diseases such as cancer or type 2 diabetes. In the current study, a quantitative metabolomics profiling strategy revealed global impairment in amino acid metabolism in mice deleted for the transcriptional ...
Halicka J J Department of Pathophysiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Bratislava, - - 2014
Transient lower esophageal sphincter relaxation (TLESR) is the major mechanism of gastroesophageal reflux (GER) but the regulation of TLESR by stimuli in the esophagus is incompletely understood. If stimuli in the esophagus can influence TLESR, then such regulation may perpetuate or limit GER. We addressed the hypothesis that acid in ...
Chauhan Nidhi N Department of Biochemistry, M. D. University, Rohtak, 124001, Haryana, - - 2014
A method is described for preparation of uricase nanoparticles (100 nm in size) and their direct immobilization onto the Au electrode. The enzyme electrode along with Ag/AgCl as reference and Pt as auxiliary electrode were connected through potentiostat/galvanostat to construct an amperometric uric acid biosensor. The enzyme electrode was characterized by ...
Kurahashi Toshihiro T Department of Biochemistry and Molecular Biology, Yamagata University School of Medicine, Yamagata, - - 2014
Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, suppresses diabetic complications via a reduction in metabolic intermediates; it also plays a role in ascorbic acid biosynthesis in mice. Because primates cannot synthesize ascorbic acid, a principle role of AKR1A appears to be the reductive detoxification of aldehydes. In ...
Schmeda-Hirschmann Guillermo G Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, 3460000 Talca, Chile. Electronic address: - - 2014
animal oils and fats from the fishes Electrophorus electricus and Potamotrygon motoro, the reptiles Boa constrictor, Chelonoidis denticulata (Geochelone denticulata) and Melanosuchus niger and the riverine dolphin Inia geoffrensis are used as anti-inflammatory agents in the Peruvian Amazon. The aim of the study was to assess the topic anti-inflammatory effect ...
Chen Guan-Yuan GY School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan; The Metabolomics Core Laboratory, Center of Genomic Medicine, National Taiwan University, Taipei, - - 2014
As fatty acids play an important role in biological regulation, the profiling of fatty acid expression has been used to discover various disease markers and to understand disease mechanisms. This study developed an effective and accurate comparative fatty acid analysis method using differential labeling to speed the metabolic profiling of ...
Barberis Antonio A Institute of Sciences of Food Production (ISPA), National Research Council (CNR), Traversa La Crucca, 3 Regione Baldinca, 07100 Li Punti, Sassari, Italy. Electronic address: - - 2014
Four fullerenes- or nanotubes-modified graphite sensor-biosensor systems (SBs), coupled with a dual-channel telemetric device, based on an ascorbate oxidase (AOx) biosensor, were developed for on line simultaneous amperometric detection of ascorbic acid (AA) and antioxidant capacity in blueberry, kiwi and orange juice. Fullerene C60 (FC60), fullerene C70 (FC70), single-walled carbon ...
Huang Shanhua S Department of Chemical and Biochemical Engineering, Faculty of Engineering, Western University, London, Ontario N6A 5B9, - - 2014
In this study, formic acid (FA) was employed as an in-situ hydrogen donor for the reductive de-polymerization of kraft lignin (KL). Under the optimum operating conditions, i.e., 300°C, 1h, 18.6wt.% substrate concentration, 50/50 (v/v) water-ethanol medium with FA at a FA-to-lignin mass ratio of 0.7, KL (Mw∼10,000g/mol) was effectively de-polymerized, ...
Moyo Mack M Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, Private Bag X01, Scottsville 3209, South - - 2014
Micropropagation of Hypoxis hemerocallidea Fisch. and C.A. Mey was used as a model system to study the influence of cytokinins (CKs) on plant regeneration and biochemical accumulation of hydroxybenzoic and hydroxycinnamic acid derivatives in organ and callus cultures and their antioxidant activity. Fourteen free phenolic acids were detected using ultra ...
Wu Hongqin H State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China; Biomass Energy Research Center, Shanghai Jiao Tong University, Shanghai 200240, - - 2014
Biodiesel quality associated with biochemical components of Chlorella pyrenoidosa and Scenedesmus obliquus under different nitrate levels were investigated. The highest lipid contents of 54.5% for C. pyrenoidosa and 47.7% for S. obliquus were obtained in nitrate absence. Carbohydrate peaked at 0.3gL(-1) with values of 40.7% for C. pyrenoidosa and 42.5% ...
Itoh Kazue K Faculty of Nutritional Sciences, Nakamura Gakuen University, Fukuoka, Japan. Electronic address: - - 2014
Insulin resistance is central to the etiology of the metabolic syndrome cluster of diseases. Evidence suggests that a high-fat diet is associated with insulin resistance, which may be modulated by dietary fatty acid composition. We hypothesized that high saturated fatty acid intake increases insulin and gastric inhibitory polypeptide (GIP) secretion. ...
Gómez J J Department of Chemical Engineering, Food Technology, Faculty of Sciences, Campus Río San Pedro, PB 40, Puerto Real, University of Cadiz 11510, Spain. Electronic address: - - 2015
Winemaking of musts acidified with up to 3g/L of gypsum (CaSO4 2H2O) and tartaric acid, both individually and in combination, as well as a chemical modeling have been carried out to study the behaviour of these compounds as acidifiers. Prior to fermentation gypsum and tartaric acid reduce the pH by ...
Kljak Kristina K Department of Animal Nutrition, Faculty of Agriculture, University of Zagreb, Svetošimunska cesta 25, 10 000 Zagreb, Croatia. Electronic address: - - 2015
Carotenoids, which occur naturally in corn grains, have been associated with reduced risk of degenerative diseases. The aim of this research was to measure the carotenoid content of hexane extracts of six commercial high-yield corn hybrids and determine the relationship between carotenoid content and antioxidant activity. Levels of lutein, zeaxanthin, ...
Ohminami Hirokazu H Department of Clinical Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, - - 2014
A dietary combination of sucrose and linoleic acid strongly contributes to the development of metabolic disorders in Zucker fatty rats. However, the underlying mechanisms of the metabolic disorders are poorly understood. We hypothesized that the metabolic disorders were triggered at a stage earlier than the 8 weeks we had previously ...
Chen Wenting W College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, - - 2015
The objective of this study was to evaluate the effects of charge-carrying amino acids (lysine (Lys), arginine (Arg), aspartic acid (Asp) and glutamic acid (Glu)) on the gelatinization and retrogradation properties of potato starch. Acidic amino acids (Asp and Glu) showed a decreasing trend in swelling power and granule size ...
Al-Bachir Mahfouz M Radiation Technology Dep., Atomic Energy Commission of Syria, P.O. Box: 6091, Damascus, Syria. Electronic address: - - 2015
The present study evaluated the quality of pistachio oil, as a function of irradiation, to determine the dose level causing undesirable changes to pistachio oil. Physicochemical fatty acid composition, acidity value, peroxide value, iodine value specification number, thiobarbituric acid (TBA) value and colour of pistachio oil extracted from samples treated ...
Aoki Natsumi N Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, - - 2014
Food deprivation (FD) induces hepatic steatosis in both rodents and humans. Although body composition, age, and sex influence hepatic triglyceride (TG) levels after FD, whether feeding patterns affect FD-induced liver TG increases is unknown. We hypothesized that restricted feeding (RF) of 1 meal per day during the active or inactive ...
Braverman Alexis A Feinberg School of Medicine of Northwestern University, Chicago, - - 2014
The use of circulating cell-free nucleic acid for prenatal aneuploidy screening has been rapidly accepted by patients and clinicians. We sought to compare decisions after a positive sequential screen and circulating cell-free nucleic acid assay. We reviewed results from sequential screening and circulating cell-free nucleic acid analyses in this retrospective ...
de Vries Paul S PS Department of Epidemiology, Erasmus Medical Center, the Netherlands; NUTRIM School for Nutrition, Toxicology and Metabolism, Departments of Complex Genetics, Cluster of Genetics and Cell Biology, Maastricht University, the - - 2014
Prenatal polyunsaturated fatty acid (PUFA) concentrations may be involved in the prenatal programming of adiposity. In this study we therefore explored the association between maternal PUFA concentrations, measured up to four times during pregnancy, and offspring adiposity at age 7 in 234 mother-child pairs of the Maastricht Essential Fatty Acid ...
Kwak Ho-Seok HS Department of Laboratory Medicine, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine, Seoul, Republic of - - 2014
Little is known on how the dose and timing of exposure co-influence the cumulative concentration of fatty acids ethyl esters (FAEEs) in meconium. The objective of the study was to assess the cumulative concentration of FAEEs in meconium as a biomarker of light, moderate or heavy prenatal alcohol exposure occurring ...
Choi Anna L AL Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA. Electronic address: - - 2014
Methylmercury, a worldwide contaminant of fish and seafood, can cause adverse effects on the developing nervous system. However, long-chain n-3 polyunsaturated fatty acids in seafood provide beneficial effects on brain development. Negative confounding will likely result in underestimation of both mercury toxicity and nutrient benefits unless mutual adjustment is included ...
Strickland Alan D AD 101 Waterlily, Lake Jackson, TX 77566, United States. Electronic address: - - 2014
This hypothesis states that cerebral palsy (CP), autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD) are all caused by an exaggerated central nervous system inflammatory response to a prenatal insult. This prenatal insult may be one or more episodes of ischemia-reperfusion, an infectious disease of the mother or the fetus, ...
Kim Hye-Ryun HR Division of Plant Biosciences, School of Plant Biosciences, Kyungpook National University, Daegu 702-701, - - 2014
To investigate the physicochemical properties of unripe peach-Prunus persica cv. Mibaekdo (Mibaekdo) and Prunus persica cv. Nagasawa Hakuho (Nagasawa Hakuho) as an alternative to food supplement while Japanese apricot (Prunus mume cv. Backaha) (Backaha) was used as a control sample. The unripe fruits were analyzed for soluble solid ( ˚Brix), ...
Muttagi Gopika C GC Department of Food Science and Nutrition, GKVK, UAS, Bengaluru, 560065 - - 2014
Shelf life of two products namely chikki and oilseed butter were evaluated. Sunflower was substituted for groundnut at three levels (0, 50 and 100 %). Products were stored up to 2 months in ambient conditions (25-30 °C; RH 40-60 %). Chikki was packed in Low density polyethylene (LDPE) and laminated pouches and oil seed ...
Bhise Suresh S Department of Food Science & Technology, Punjab Agricultural University, Ludhiana, 141004 Punjab - - 2014
The polyols namely glycerol, sorbitol and mannitol were incorporated at 2, 4 and 6 % level in flour for bread making and their effect on textural properties, bread making quality and sensory acceptability of bread was studied. The effect of incorporation revealed the increased bake absorption, bread weight and decreased specific ...
Hu Rong R Department of Anesthesia, Third Xiangya Hospital, Central South University, Changsha, Hunan Province, - - 2014
This study established an aged rat model of cognitive dysfunction using anesthesia with 2% isoflurane and 80% oxygen for 2 hours. Twenty-four hours later, Y-maze test results showed that isoflurane significantly impaired cognitive function in aged rats. Gas chromatography-mass spectrometry results showed that isoflurane also significantly increased the levels of ...
Kim Min Woo MW Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, South - - 2014
Although there is accumulating evidence regarding the additional protective effect of folic acid against adverse pregnancy outcomes other than neural tube defects, these effects have not been elucidated in detail. We evaluated whether folic acid supplementation is associated with favorable maternal and fetal outcomes. This was a secondary analysis of ...
Ganjali Dashti Marjan M School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia ; Enteric Diseases Research Cluster, Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia (USM), 11800 Penang, - - 2014
The biosynthesis of biomedical products including lipid and gamma-linolenic acid (GLA) by Cunninghamella bainieri 2A1 was studied in repeated batch fermentation. Three key process variables, namely, glucose concentration, ammonium tartrate concentration, and harvesting time, were optimized using response surface methodology. Repeated batch fermentation was carried out by the cultivation of ...
Libiaková Michaela M Department of Plant Physiology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, - - 2014
The trap of the carnivorous plant Venus flytrap (Dionaea muscipula) catches prey by very rapid closure of its modified leaves. After the rapid closure secures the prey, repeated mechanical stimulation of trigger hairs by struggling prey and the generation of action potentials (APs) result in secretion of digestive fluid. Once ...
Martin Gregory J O GJ Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, - - 2014
Many species of microalgae produce greatly enhanced amounts of triacylglycerides (TAGs), the key product for biodiesel production, in response to specific environmental stresses. Improvement of TAG production by microalgae through optimization of growth regimes is of great interest. This relies on understanding microalgal lipid metabolism in relation to stress response ...
Santana Lorena C L R LC Departamento de Farmácia, Laboratório de Pesquisa em Neuroquímica Experimental do Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Piauí, 64049-550 Teresina, PI, Brazil ; Programa de Pós-Graduação em Biotecnologia (RENORBIO), Universidade Federal do Piauí, 64049-550 Teresina, PI, - - 2014
The present study primarily aims to identify the relative density and the fatty acids (methyl esters) content present in the standardized ethanol extract of leaves of M. glomerata (EPMG). Meanwhile, in a second moment, this study evaluated the effects of the EPMG on the levels of amino acids in the ...
Ounnas Fayçal F TIMC-IMAG CNRS UMR 5525, Laboratoire PRETA, Cœur et Nutrition, Université Joseph Fourier, Grenoble, France ; Laboratory of Fundamental and Applied Bioenergetics (LBFA), Université Grenoble Alpes, Grenoble, France ; Inserm, U1055, Grenoble, - - 2014
These studies were designed to assess whether wheat polyphenols (mainly ferulic acid [FA]) increased the very-long-chain omega-3 fatty acids (VLC n-3) [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] in rats. Wheat aleurone (WA) was used as a dietary source of wheat polyphenols. Two experiments were performed; in the first one, ...
Kroghsbo Stine S National Food Institute, Technical University of Denmark, Søborg, - - 2014
Acid hydrolyzed wheat proteins (HWPs) are used in the food and cosmetic industry as emulsifiers. Cases of severe food allergic reactions caused by HWPs have been reported. Recent data suggest that these reactions are caused by HWPs produced by acid hydrolysis. To examine the sensitizing capacity of gluten proteins per ...
Weidner Stanisław S Department of Biochemistry, University of Warmia and Mazury, Oczapowskiego Street 1A, 10-957 Olsztyn, Poland. - - 2014
The material for this study consisted of stratified seeds of Vitis californica submitted to germination under optimum conditions (+25 °C) or under chill stress (+10 °C), also followed by recovery. It has been determined that the germinating seeds contain considerable amounts of tannins, catechins as well as phenolic acids such ...
Li Xingsong X Department of Electronic Engineering, Fudan University, HenglongPhysic Building, Room 212, Shanghai 200433, China Department of Healthcare, Philips Research China, Shanghai 200233, - - 2014
Backscatter and attenuation parameters are not easily measured in clinical applications due to tissue inhomogeneity in the region of interest (ROI). A least squares method(LSM) that fits the echo signal power spectra from a ROI to a 3-parameter tissue model was used to get attenuation coefficient imaging in fatty liver. ...
Koroleva Olga O Bach Institute of Biochemistry of the Russian Academy of Sciences, Leninsky Prospekt, 33, bld 2, 119071 Moscow, Russia. - - 2014
Antioxidant capacity (AOC) against peroxyl radical and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) radical cation was measured for a series of p-hydroxybenzoic (HB) and p-hydroxycinnamic (HC) acids at different pH. Quantum-chemical computation was performed using Gaussian 3.0 software package to calculate the geometry and energy parameters of the same compounds. Significant ...
Hadian Zahra Z Faculty of Agriculture, Tarbiat Modares University and Academic Staff of National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical - - 2014
Omega-3 fatty acids (FAs) have been shown to prevent cardiovascular disease. The most commonly used omega-3 fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are highly vulnerable to oxidation and therefore, have short shelf life. Recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 FAs. Several ...
Talaat Iman M IM Botany Department, National Research Centre, Cairo, - - 2014
The effects of foliar application of different concentrations of amino acids (tyrosine and phenylalanine) and phenolic acids (trans-cinnamic acid, benzoic acid and salicylic acid) on growth, pigment content, hormones levels and essential oil content of Ammi visnaga L were carried out during two successive seasons. It is clear that foliar ...
Day P E L - - 2013
Placental glutamine synthesis has been demonstrated in animals and is thought to increase the availability of this metabolically important amino acid to the fetus. Glutamine is of fundamental importance for cellular replication, cellular function and inter-organ nitrogen transfer. The objective of this study was to investigate the role of glutamate/glutamine ...
Shrestha Uttam U Department of Anatomy, Institute of Medical sciences, Banaras Hindu University, - - 2013
Alcohol is a potent teratogen inducing oxidative stress as well as a massive wave of apoptosis in the developing brain as well as oxidative stress. It affects brain including cerebellum, hippocampus and cerebral cortex resulting into motor and cognitive deficits. Alcohol depletes folic acid from the body which is essential ...
Liu Biao B Department of Hand Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, - - 2013
In this study, we aimed to explore the role of ursolic acid in the neural regeneration of the injured sciatic nerve. BALB/c mice were used to establish models of sciatic nerve injury through unilateral sciatic nerve complete transection and microscopic anastomosis at 0.5 cm below the ischial tube-rosity. The successfully ...
Okada Emiko - - 2013
Perfluoroalkyl acids (PFAAs) are persistent organic pollutants that are used in a wide range of consumer products. Recent epidemiological studies have shown that prenatal exposure to toxic levels of PFAAs in the environment may adversely affect fetal growth and humoral immune response in infants and children. Here we have characterized ...
Barceló-Coblijn Gwendolyn - - 2013
Fetal alcohol syndrome is the most severe expression of the fetal alcohol spectrum disorders (FASD). Although alterations in fetal and neonate brain fatty acid composition and cholesterol content are known to occur in animal models of FASD, the persistence of these alterations into adulthood is unknown. To address this question, ...
Jones Kenneth Lyons - - 2013
Gastroschisis is a congenital abdominal wall defect where there is herniation of abdominal organs. Optimal maternal nutritional intake, in particular, fatty acids, are vital for proper growth and development of the fetus. This pilot case-control study explored the association of several biomarkers of fatty acids and gastroschisis. Between 2008 and ...
Giardini Valentina - - 2013
OBJECTIVES: To evaluate whether a relationship exists between season at conception and occurrence of Isolated Spina Bifida (ISB). STUDY DESIGN: All fetuses with prenatal diagnosis of ISB were analyzed according to date of conception. We compared the seasonal rates of conception between ISB fetuses and a control group consisting of ...
Larqué Elvira - - 2013
PURPOSE OF REVIEW: Placental nutrient uptake and transfer may have a unique role, as changes in trophoblast nutrient-sensing signaling pathways regulate cell metabolism and may affect the fetal growth and health programming in the offspring. RECENT FINDINGS: The functionality of the placenta could affect the neonatal adiposity and the fetal ...
Ashworth Cheryl J - - 2013
This study compared maternal plasma amino acid concentrations, placental protein secretion in vitro and fetal body composition and plasma amino acid and hormone concentrations in feto-placental units from the smallest and a normally-sized fetus carried by Large White×Landrace or Meishan gilts on Day 100 of pregnancy. Compared with Large White×Landrace, ...
Lamb Michelle - - 2013
This Report from the Field describes a folic acid awareness event hosted by a College of Pharmacy in conjunction with a local YWCA in observation of National Birth Defects Prevention Month and includes a discussion of the disparity between folic acid awareness and consumption and proposes a new tool to ...
Skilton Michael R - - 2012
BACKGROUND: Impaired fetal growth is independently associated with an increased risk of cardiovascular events in adulthood. Prevention strategies that can be implemented during adulthood have not been identified. OBJECTIVE: The objective was to determine whether habitual omega-3 (n-3) fatty acid intake is associated with the rate of increase of carotid ...
Tasdemir Seda - - 2012
Objective:  To determine the protective effects of hyaluronic acid and chondroitin sulfate in treating urinary tract infections in a rat model. Methods:  A total of 28 rats, which were induced with urinary tract infections through intravesical administration of Escherichia coli, were included in the study. By random selection, they were equally ...
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