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Rizzuti Antonino A Dipartimento di Ingegneria Civile, Ambientale, del Territorio, Edile e di Chimica, Politecnico di Bari, Via Orabona, 4, I-70125 Bari, Italy. Electronic address: - - 2015
The effect of 2-chloroethylphosphonic acid (Ethephon, in the following ETH) as abscising agent on cv. Crimson Seedless table grape was investigated by means of Fruit Detachment Force (FDF) and Fruit Drop (FD) analyses combined with a metabolomic study carried out by High Resolution Mass Spectrometry (HRMS) and Nuclear Magnetic Resonance ...
Gelzo Monica M Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, 80131, Napoli, - - 2014
Pseudoalteromonas haloplanktis, a psychrotrophilic marine bacterium of biotechnological interest, shows anti-biofilm properties and is particularly relevant for cold storage of vacuum packed seafood. We focused our interest on the activation of cholesterol metabolism in this bacterium as the presence in its genome of a putative 3-ketosteroid-Δ(1) -dehydrogenase. This study reports ...
Yanagi Tadahiro T Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, - - 2014
Deficiency of Δ(4) -3-oxosteroid 5β-reductase (5β-reductase), a bile acid synthesis disorder, presents findings of neonatal cholestasis and hyper-3-oxo-Δ(4) bile aciduria. The 5β-reductase enzyme participates in not only bile acid synthesis but also hepatic steroid metabolism. Deficiency of 5β-reductase includes 2 types: primary deficiency, with an SRD5B1 gene mutation; and secondary ...
Zhong Chunying C School of Environmental Engineering, Wuhan Textile University, Wuhan 430073, China; School of Chemistry and Life Science, Hubei University of Education, Wuhan 430205, - - 2014
A novel strain (designated as SW-2) which could convert chromotropic acid into bioflocculants was isolated from chromotropic acid wastewater. Conditions for bioflocculants production were optimized by response surface methodology (RSM) and determined to be inoculum size 7.74%, initial pH 6.9, and CODCr of the chromotropic acid wastewater 425mg/L. The yielded ...
Sun Yuan-Qiang - - 2014
A mitochondria-specific fluorescent probe for NO (1) was synthesized by the direct conjugation of a pyronin dye with one of amino groups of o-phenylenediamino (OPD). The probe could selectively detect NO over dehydroascorbic acid (DHA), ascorbic acid (AA), methylglyoxal (MGO), as well as the reactive oxygen/nitrogen species (ROS/RNS) with the ...
Xu Piao P College of Environmental Science and Engineering, Hunan University, Changsha, 410082, Hunan, People's Republic of - - 2014
This study examines the role of oxalic acid in the uptake of Cd and participation in detoxification process in Phanerochaete chrysosporium. Cd-induced oxalic acid secretion was observed with growth inhibition and enzyme inactivation (LiP and MnP) of P. chrysosporium. The peak value of oxalic acid concentration was 16.6 mM at initial ...
Shih I-Chih IC Department of Chemistry, National Taiwan University, Taipei, 10617, Taiwan, - - 2014
The photophysical properties of fluorescent Hammett acidity indicator derived from 3,4,5,6-tetrahydrobis(pyrido[3,2-g]indolo)[2,3-a:3',2'-j]acridine (1a), 6-bis(pyrido[3,2-g]indol-2'-yl)pyridine (1b) and their analogues have been investigated in sulfuric acid solutions by means of absorption, fluorimetry, relaxation dynamics and computational approach. These new indicators undergo a reversible protonation process in the Hammett acidity range of H0 < ...
He Lipeng L Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu province, China. - - 2014
A metallosupramolecular polymer (MP-Zn) bearing dibenzo-24-crown-8 (DB24C8) arms is constructed by coordinating Zn(2+) with a conjugated bis-terpyridine ligand, which indicates concentration-dependent emissions from cyan to white to yellow. Successively, reversible emissions are realized by acid-base controllable recognition of DB24C8 moieties in MP-Zn with dialkylammonium ion centers.
Kikuchi Yusuke Y Graduate School of Agriculture, Hokkaido University, Sapporo, 060-8589, - - 2014
Arbuscular mycorrhizal (AM) fungi accumulate a massive amount of phosphate as polyphosphate to deliver to the host, but the underlying physiological and molecular mechanisms have yet to be elucidated. In the present study, the dynamics of cationic components during polyphosphate accumulation were investigated in conjunction with transcriptome analysis. Rhizophagus sp. ...
Inouchi Toshifumi T Graduate School of Materials Science, Nara Institute of Science and Technology, NAIST, 8916-5 Takayama, Ikoma, Nara 630-0192 - - 2014
Herein we report on the synthesis and acid-responsive emission properties of donor-acceptor (D-A) molecules that contain a thienothiophene unit. 2-Arylthieno[3,2-b]thiophenes were conjugated with an N-methylbenzimidazole unit to form acid-responsive D-A-type fluorophores. The D-A-conjugated fluorophores showed intense intramolecular charge-transfer (ICT) emission in response to acid. The effect of the substitution on ...
Papafragkakis Haris H Haris Papafragkakis, Kinesh Changela, Taruna Bhatia, Mel A Ona, Anju Malieckal, Vani Paleti, Sury Anand, Division of Gastroenterology, the Brooklyn Hospital Center, New York Presbyterian Healthcare System, Brooklyn, NY 11201, United - - 2014
The use of hyaluronic acid and dextranomer (Solesta, Salix) injection in the anal canal is an emerging modality in the treatment of fecal incontinence. However, little is known regarding the endoscopic and radiological appearance following injection of this ano-rectal bulking agent. We report computed tomography and endoscopic findings after hyaluronic ...
Torsello Mauro M Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Via Marzolo 1, 35131 Padova, Italy. - - 2014
Oxo-dipeptides and thio-dipeptides are built via condensation between couples of amino acids and amino thioacids, the latter with the carbonyl oxygen replaced by an sp(2) sulfur. We explored via in silico methods (PBE0/6-31G(d,p) and PBE0/6-311G(d,p)) all the possible combinations and built 800 dipeptides, whose structures were fully optimized. Maps of ...
Wang Min M Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 1345 West 16th Street, Room 202, Indianapolis, IN 46202, - - 2014
The reference standards methyl 4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (10a), methyl 4-(2-methyl-5-(ethoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (10b) and corresponding precursors 4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid (11a), methyl 4-(2-methyl-5-(ethoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid (11b) were synthesized from methyl crotonate and 3-amino-4-methylbenzoic acid in multiple steps with moderate to excellent yields. The target tracer [(11)C]methyl 4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate ([(11)C]10a) and [(11)C]methyl 4-(2-methyl-5-(ethoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate ([(11)C]10b) were prepared from their corresponding ...
Ma Kai-Guo - - 2014
Highly fluorescent CdTe quantum dots (QDs) with emission in red to near-infrared (NIR) wavelength were successfully prepared by using 3-mercaptobutyric acid (3MBA) as capping agent. The maximum of quantum yield (QY) could reach up to 82% for QDs with emission peak at 686 nm and FWHM of 66 nm at ...
Jarvis Claire L CL Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United - - 2014
Secondary amines react with thiosalicylaldehydes in the presence of catalytic amounts of acetic acid to generate ring-fused N,S-acetals in redox-neutral fashion. A broad range of amines undergo α-sulfenylation, including challenging substrates such morpholine, thiomorpholine, and piperazines. Computational studies employing density functional theory indicate that acetic acid reduces the energy barriers ...
Wang Zhanyun Z Institute for Chemical and Bioengineering, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, - - 2014
We quantify global emissions of C4-C14 perfluoroalkyl carboxylic acid (PFCA) homologues during the life-cycle of products based on perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorooctane sulfonyl fluoride (POSF), and fluorotelomer compounds. We estimate emissions of 2610-21400 tonnes of C4-C14 PFCAs in the period from 1951 to 2015, and project 20-6420 ...
Way Jenilee D JD Department of Oncology, University of Alberta, 11560 University Ave, Edmonton AB, T6G 1Z2, - - 2014
(18)F-labeled amino acids are important PET radiotracers for molecular imaging of cancer. This study describes synthesis and radiopharmacological evaluation of 2-amino-5-(4-[(18)F]fluorophenyl)pent-4-ynoic acid ([(18)F]FPhPA) as a novel amino acid radiotracer for oncologic imaging. (18)F]FPhPA was prepared using Pd-mediated Sonogashira cross-coupling reaction between 4-[(18)F]fluoroiodobenzene ([(18)F]FIB) and propargylglycine. The radiopharmacological profile of [(18)F]FPhPA ...
Liu Quan-Yu - - 2014
A new steroidal ester, beta-rosaterol palmitate (1) along with ten known compounds, uvaol(2), 3-epi-ursolic acid (3), 2alpha, 3beta, 24-trihydroxyolean-12-en-28-oic acid (4), 2alpha, 3alpha, 24-trihydroxyurs-12-en-28-oic acid (5), 2alpha, 3alpha, 24-trihydroxyolean-12-en-28-oic acid (6), 2alpha, 3alpha, 24-trihydroxyolean-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester (7), (Z)-9-hexadecenoic acid (8), octacosyl alcohol (9), beta-sitosterol (10) and beta-daucosterol (11), has been ...
Mitra Tapobrata - - 2014
We report the first example of a highly diastereoselective Garratt-Braverman cyclization leading to the synthesis of chiral aryl naphthalene-amino acid hybrids in excellent yields. The stereogenecity in the amino acid has induced high diastereoselectivity for the reaction. Computations based on Density Functional Theory indicated a lower activation free energy barrier ...
Lewis David Y DY Cancer Research United Kingdom-Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United - - 2014
Tumors are often characterized by high levels of de novo fatty acid synthesis. The kinetics of acetate incorporation into tricarboxylic acid cycle intermediates and into lipids suggest that detection of tumors with [1-(11)C]acetate PET could be improved by imaging at later time points. The uptake and metabolism of [1-(11)C], [1-(13)C], ...
Fordahl Steve C SC Department of Nutrition, University of North Carolina at Greensboro, 318 Stone Building, P.O. Box 26170, Greensboro, NC 27402-6170, United States. Electronic address: - - 2014
Manganese (Mn) exposure interferes with GABA uptake; however, the effects of Mn on GABA transport proteins (GATs) have not been identified. We sought to characterize how Mn impairs GAT function in primary rat astrocytes. Astrocytes exposed to Mn (500μM) had significantly reduced (3)H-GABA uptake despite no change in membrane or ...
Tsukagoshi Kensuke K Hijirigaoka Hospital, 214-22 Funaoka, Date, Hokkaido 052-0014, - - 2014
Benzoic acid is a typical substrate for monocarboxylic acid transporters (MCTs), and easily taken up from the apical membranes of Caco-2 cells by MCTs. However, some benzoic acid derivatives were sparingly taken up by Caco-2 cells. To elucidate the mechanism of lower uptake of the derivatives, we investigated the effect ...
Ferreira Miguel F MF Centro de Química (CQ-UM), Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal. - - 2014
The availability of commercial (68)Ge/(68)Ga cyclotron-independent (68)Ga(3+) generators is making Positron Emission Tomography (PET) accessible to most hospitals, which is generating a surge of interest in the design and synthesis of bi-functional chelators for Ga(3+). In this work we introduce the NO2A-N-(α-amino)propionic acid family of chelators based on the triazacyclononane ...
Ishimaru Hideki H 1 Department of Radiology, National Hospital Organization Nagasaki Medical Center, Omura, - - 2014
OBJECTIVE. The purpose of this article is to investigate whether there is a difference in susceptibility to transcatheter arterial chemoembolization between hepatocellular carcinomas (HCCs) showing high uptake and those showing low uptake of gadoxetic acid in the hepatobiliary phase of MRI. MATERIALS AND METHODS. One hundred HCCs that achieved optimal ...
Nikrad Mrinalini P MP School of Marine Science and Policy, University of Delaware, Lewes, DE - - 2014
Heterotrophic bacteria are well known to be key players in the turnover of dissolved organic material (DOM) in the oceans, but the relationship between DOM uptake and bacterial clades is still not well understood. Here we explore the turnover and single-cell use of glucose, an amino acid mixture, N-acetyl glucosamine ...
Dong Shubin S Lab of Systematic Evolution and Biogeography of Woody Plants, College of Nature Conservation, Beijing Forestry University, Beijing 100083, PR - - 2014
Acyl-acyl carrier protein (ACP) thioesterases (TE EC 3.1.2.14) are fatty acid biosynthesis key enzymes that determine fatty acid carbon chain length in most plant tissues. A full-length cDNA corresponding to one of the fatty acyl-ACP thioesterase (Fat) genes, designated LcFatB, was isolated from developing Lindera communis seeds using PCR and ...
Akulov Katherine - - 2014
Femtosecond UV-Vis pump-probe spectroscopy was employed to study the acid effect on curcumin in the excited state. Curcumin in solutions of weak acids was found to be a photobase forming a protonated curcumin within a few tens of picoseconds from the time of excitation. The excited-state-protonation reaction is also observed ...
Wang Min M Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 1345 West 16th Street, Room 202, Indianapolis, IN 46202, - - 2014
The reference standard 2-fluoro-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid was synthesized from 2,5-dimethyl-2,5-hexanediol and 2-fluoro-4-methylbenzoic acid in 10 steps with 3% overall chemical yield. The precursor 2-nitro-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid was synthesized from 2,5-dimethyl-2,5-hexanediol and dimethyl-2-nitroterephthalate in seven steps with 2% overall chemical yield. The target tracer 2-[(18)F]fluoro-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid was synthesized from its nitro-precursor by the ...
Andrews M M Micronutrient Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, El Líbano 5524, Macul, Santiago, - - 2014
Calcium, phytic acid, polyphenols and fiber are major inhibitors of iron absorption and they could be found in excess in some diets, thereby altering or modifying the iron nutrition status. The purpose of this study is to evaluate the effect of calcium, tannic acid, phytic acid, and pectin over iron ...
Schneider Hannah H Molecular Cell Biology Laboratory Internal Medicine IV, University of Heidelberg, Im Neuenheimer Feld 345, 69120 Heidelberg, - - 2014
The mechanism of cellular fatty acid uptake is highly relevant for basic and clinical research. Previous work has demonstrated that fatty acid uptake is facilitated by cell surface membrane proteins as well as by intracellularly localized enzymes. Here, the exogenous expression of the CD36/FAT glycoprotein and the acyl-CoA synthetases FATP4 ...
Jepperson Maria A MA Mayo Clinic Jacksonville, Jacksonville, Florida, - - 2014
Dual energy computed tomography (DECT) utilizes the material change in attenuation when imaged at two different energies to determine the composition of urinary calculi as uric acid or non-uric acid. We discuss a series of case reports illustrating DECT's ability to provide immediate determination of uric acid versus non-uric acid ...
Hu Lina Y LY Department of Biomedical Engineering, University of California Davis, Davis, CA, - - 2014
The integrin αvβ6 is overexpressed in a variety of aggressive cancers and serves as a prognosis marker. This study describes the conjugation, radiolabeling, and in vitro and in vivo evaluation of four chelators to determine the best candidate for (64)Cu radiolabeling of A20FMDV2, an αvβ6 targeting peptide. Four chelators were ...
Khalifeh-Soltani Amin A 1] Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA. [2] Lung Biology Center, University of California, San Francisco, San Francisco, California, USA. [3] Department of Medicine, University of California, San Francisco, San Francisco, California, - - 2014
Fatty acids are integral mediators of energy storage, membrane formation and cell signaling. The pathways that orchestrate uptake of fatty acids remain incompletely understood. Expression of the integrin ligand Mfge8 is increased in human obesity and in mice on a high-fat diet, but its role in obesity is unknown. We ...
Cheng Xiao X State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University , Changchun 130012, P. R. - - 2014
A novel family of organoboron compounds 1-4 with bright near-infrared (NIR) emissions in the crystalline state was synthesized. They show a morphology-dependent emission "ON" and "OFF" feature and volatile acid/base-induced fluorescence saltation which allow the realization of reversible solid-state fluorescence switching in the NIR region by totally different procedures: mechanical ...
Valan Arasu Mariadhas M Grassland and Forage Division, National Institute of Animal Science, RDA, Cheonan, South - - 2014
Adipogenesis is very much important in improving the quality of meat in animals. The aim of the present study was to investigate the in vitro and in vivo adipogenesis regulation properties of Lolium multiflorum on 3T3-L1 pre-adipocytes and mice. Chemical composition of petroleum ether extract of L. multiflorum (PET-LM) confirmed ...
Erez Yuval - - 2014
Steady-state and time-resolved emission techniques were employed to study the acid-base effects on the UV-Vis spectrum of curcumin in several organic solvents. The fluorescence-decay rate of curcumin increases with increasing acid concentration in all the solvents studied. In methanol and ethanol solutions containing about 1M HCl, the short-wavelength fluorescence (λ<560nm) ...
Dubikovskaya Elena E Department of Chemistry, École Polytechnique Fédérale de Lausanne, Lausanne, - - 2014
The ability of white and brown adipose tissue to efficiently take up long-chain fatty acids is key to their physiological functions in energy storage and thermogenesis, respectively. Several approaches have been taken to determine uptake rates by cultured cells and primary adipocytes including radio- and fluorescently labeled fatty acids. In ...
Nural Yahya Y Department of Chemistry, Faculty of Pharmacy, Mersin University, 33169 Mersin, - - 2014
The acid dissociation constants of potential bioactive fused ring thiohydantoin-pyrrolidine compounds were determined by potentiometric titration in 20% (v/v) ethanol-water mixed at 25 ± 0.1°C, at an ionic background of 0.1 mol/L of NaCl using the HYPERQUAD computer program. Proton affinities of potential donor atoms of the ligands were calculated by ...
Higashi Kyohei K Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, - - 2014
Polyamine (putrescine, spermidine and spermine) and agmatine uptake by the human organic cation transporter 2 (hOCT2) was studied using HEK293 cells transfected with pCMV6-XL4/hOCT2. The Km values for putrescine and spermidine were 7.50 and 6.76 mM, and the Vmax values were 4.71 and 2.34 nmol/min/mg protein, respectively. Spermine uptake by ...
Dopico Alex M AM Department of Pharmacology, The University of Tennessee Health Science Center Memphis, TN, - - 2014
This mini-review focuses on lipid modulation of BK (MaxiK, BKCa) current by a direct interaction between lipid and the BK subunits and/or their immediate lipid environment. Direct lipid-BK protein interactions have been proposed for fatty and epoxyeicosatrienoic acids, phosphoinositides and cholesterol, evidence for such action being less clear for other ...
Khaneghah Amin Mousavi AM Department of Food Science and Technology, Islamic Azad University, Science and Research Branch, Tehran, - - 2013
PET containers for food oil packaging were evaluated with a newly established determination method for terephthalic acid (TPA) and isophthalic acid (IPA). The analysis of monomers, TPA and IPA that migrate from PET bottles into oils was performed by HPLC with a diode array detector (DAD). Three types of commercial ...
Müller Adrienne - - 2013
The concentrative amino acid transporter ATB(0,+) (SLC6A14) is under evaluation as a target for anticancer therapy. An ATB(0,+)-selective positron emission tomography (PET) probe could advance preclinical drug development. We characterised the cationic tyrosine analogue O-2((2-[(18)F]fluoroethyl)methyl-amino)ethyltyrosine ([(18)F]FEMAET) as a PET probe for ATB(0,+) activity. Cell uptake was studied in vitro. ATB(0,+) ...
Bhattacharya Sumangala - - 2013
Obesity and insulin resistance in skeletal muscles are major features of type 2 diabetes. In the present study, we examined the potential of Sambucus nigra flower (elderflowers) extracts to stimulate glucose uptake (GU) in primary porcine myotubes and reduce fat accumulation (FAc) in Caenorhabditis elegans. Bioassay guided chromatographic fractionations of ...
Bergmann R - - 2013
The bifunctional chelating agent 2-[4,7-bis(2-pyridylmethyl)-1,4,7-triazacyclononan-1-yl]acetic acid, DMPTACN-COOH, has been found to bind strongly to copper(II), resulting in a radiocopper(II)-ligand complex that exhibits high in vivo stability. The pendant carboxylic acid group enables this derivative to be conjugated to the N-terminal amino acid residues of peptides. Exploiting this, two stabilized bombesin (BBN) ...
Xu Su - - 2013
CD36 is a multifunctional protein that enhances cellular fatty acid (FA) uptake, a key step in energy metabolism, and its dysregulation in multiple tissue sites is central to obesity-linked diabetes, a risk factor for atherosclerosis. Although CD36 has been implicated in FA uptake in a correlative way, the molecular mechanisms ...
Claudie Dhuique-Mayer - - 2013
The health benefit of a diet rich in fruits and vegetables could be attributed to the presence of a large diversity of phytochemicals, including carotenoids. Bioactivities of carotenoids greatly depend on their bioavailability that could be modulated by the presence of other dietary constituents. Because citrus juices contain diverse antioxidant ...
Shang Xiuling X CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, - - 2013
Corynebacterium glutamicum is equipped with abundant membrane transporters to adapt to a changing environment. Many amino acid transporters have been identified in C. glutamicum, but histidine uptake has not been investigated in detail. Here, we identified the aromatic amino acid transporter encoded by aroP as a histidine transporter in C. ...
Sanandiya Naresh D - - 2013
A microwave assisted synthesis of a water soluble fluorogenic interpolymeric diamide has been described involving alginic acid and polyglucuronic acid (PGA) amide of ethylenediamine (EDA), through a monoamide of PGA and EDA, in good yields (>80wt% in each step). PGA was prepared by TEMPO (2,2,6,6-tetramethyl piperidine-1-oxyl radical) mediated oxidation of ...
Jensen Pernille R - - 2013
Uptake and upshot in vivo: Straightforward methods that permit the real-time observation of organic acid influx, intracellular acidification, and concomitant effects on cellular-reaction networks are crucial for improved bioprocess monitoring and control. Herein, dynamic nuclear polarization (DNP) NMR is used to observe acetate influx, ensuing intracellular acidification and the metabolic consequences ...
Peng Juanjuan - - 2013
Nanoparticles that circulate in the bloodstream for a prolonged period of time have important biomedicine applications. However, no example of lanthanide-based nanoparticles having a long-term circulation bloodstream has been reported to date. Herein, we report on difunctional radioactive and upconversion nanoparticles (UCNP) coated with polyphosphoric acid ligand, that is ethylenediamine ...
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