Search Results
Results 251 - 300 of 1572
< 1 2 3 4 5 6 7 8 9 10 11 >
Kunešová M - - 2012
Fatty acid composition of adipose tissue changes with weight loss. Palmitoleic acid as a possible marker of endogenous lipogenesis or its functions as a lipokine are under debate. To assess the predictive role of adipose triglycerides fatty acids in weight maintenance in participants of the DIOGENES dietary intervention study. After ...
Li Hongda - - 2012
A highly reactive and selective chemodosimetric probe for cyanide was synthesized based on alkylidene Meldrum's acid as a novel cyanide reaction site. A theoretical study was conducted to rationalize the high reactivity and the photophysical properties of probe and the -CN adduct.
Ye Lidan - - 2012
Acid tolerance of Lactobacillus pentosus ATCC 8041 was improved by error-prone amplification of its genomic DNA using random primers and Taq DNA polymerase. The resulting amplification products were transferred into wild-type L. pentosus by electroporation and the transformants were screened for growth on low-pH agar plates. After only one round ...
Kim Yong Wook - - 2012
Described herein is a palladium(II)-catalyzed direct arylation of cyclic enaminones with arylboronic acids. The versatility of this method is that both electron-rich and electron-poor boronic acids can be coupled in high yields. A mixture of two Cu(II) additives was crucial for efficient cross-coupling. The role of each Cu(II) reagent appears ...
Burns T A - - 2012
Our objectives were to: (1) confirm elongation products of palmitoleic acid (16:1 cis-9) elongation in vitro using stable isotopes and (2) evaluate if exogenous supplementation of palmitoleic acid, elongation products, or both are responsible for decreased desaturation and lipogenesis rates observed with palmitoleic acid supplementation in bovine adipocytes. Stromal vascular ...
Yan Jinfei - - 2012
High acetate accumulation was produced during glucose fermentation in high cell density cultures, which is harmful to cell growth. In order to reduce the negative impact of acetate accumulation on the fermentation products, we introduced the Escherichia coli acetyl-CoA synthetase (ACS) gene into the marine microalga Schizochytrium sp. TIO1101, generating ...
Vitaglione Paola - - 2012
Human bioavailability of cocoa flavanols and phenolic acids from a cocoa-nut cream (CC) and from CC enriched with a 1·5 % (w/w) cocoa polyphenol extract in free form (FPC) or encapsulated with a gastric-resistant high-amylose maize starch (EPC), was studied. In a randomised cross-over protocol, with 1-week wash-out in between, twelve ...
Liu An-Hua - - 2012
Steric bulk controls CO(2) absorption: N-substituted amino acid salts in poly(ethylene glycol) reversibly absorb CO(2) in nearly 1:1 stoichiometry. Carbamic acid is thought to be the absorbed form of CO(2) ; this was supported by NMR and in situ IR spectroscopy, and DFT calculations. The captured CO(2) could be converted ...
Cho Suhyung - - 2012
Sialic acids are located on the terminal positions of glycan on a cell surface, which play important role in the spread and metastasis of cancer cells and infection of pathogen. For their detection and diagnosis, the finding of sialic acid specific ligand is an essential prerequisite. Here, RNA aptamer for ...
Sokolov Dmitriy N - - 2012
Influenza is a widespread respiratory infection. Every year it causes epidemics, quickly spreading from country to country, or even pandemics, involving a significant part of the human population of the earth. Being a highly variable infection, influenza easy accumulates the resistance mutations to many antivirals. Usnic acid, a dibenzofuran originally ...
Rillahan Cory D - - 2012
Click 'n' chips: Azide and alkyne-bearing sialic acids (purple diamond; see picture) were subjected to high-throughput click chemistry to generate a library of sialic acid analogues. Microarray printing of the library and screening with the siglec family of sialic-acid-binding proteins, led to the identification of high-affinity ligands for siglec-9 and ...
Santos S - - 2012
Two novel HLA-A29 alleles were described. A*29:39 differs from A*29:02:01 by three clustered amino acid replacements at α1 domain, T73>I73, A76>V76 and N77>D77. A*29:40 shows one nucleotide difference regarding A*29:02:01 allele, resulting in one amino acid substitution at position 154, E154>G154.
Zhao Kai - - 2012
A lactic acid bacterium with high tolerance of temperature and lignocellulose derived inhibitor was isolated and characterized as Pediococcus acidilactici DQ2. The strain used in the simultaneous saccharification and fermentation (SSF) for high titer lactic acid production at the high solids loading of corn stover. Corn stover was pretreated using ...
Zong Geng G Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Graduate University of the Chinese Academy of Sciences, Shanghai, - - 2012
Palmitoleic acid has been shown to regulate adipokine expression and systemic metabolic homeostasis in animal studies. However, its association with human metabolic diseases remains controversial. We aimed to investigate associations of erythrocyte palmitoleic acid with adipokines, inflammatory markers, and metabolic syndrome (MetS) in a Chinese population. Erythrocyte fatty acids were ...
Chen Xiaojiao - - 2012
In this study, amphiphilic polyethylenimine-graft-thioctic acid (PEI-TA) and polyethylenimine-graft-lauric acid (PEI-LA) were synthesized. Both PEI-TA and PEI-LA could self-assemble into micelles. Due to the existence of disulfide-linked rings at the end of hydrophobic moieties, PEI-TA could form stable micelles with disulfide crosslinked cores (PEI-TA-SS). In comparison with the PEI-LA micelle, ...
Bjørke-Monsen Anne Lise AL Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway. - - 2013
Epidemiological studies on the association between pregnancy outcomes and use of periconceptional folic acid are often based on maternal reported intake. Use of folic acid during pregnancy is associated with a higher socioeconomic status known to have an impact on diet quality. We have studied plasma B vitamin status according ...
Kanbay Mehmet - - 2012
Background: Chronic kidney disease (CKD) is associated with increased risk for cardiovascular (CV) disease and is also associated with elevated uric acid, which is emerging as a nontraditional CV risk factor. We therefore evaluated uric acid as a risk factor for CV disease in subjects presenting to nephrologists with CKD ...
Yang Minghui - - 2012
Mesoporous vanadium nitride (VN) with high surface area and good electrical conductivity was prepared by a solid-solid phase separation method from a Zn containing vanadium oxide, Zn(3)V(2)O(8). The VN supported Pd catalyst exhibited significant catalytic activity for formic acid oxidation.
Albabtain Monirah A - - 2012
Background : Antioxidant drugs such as N-acetylcysteine (NAC) and ascorbic acid have been evaluated in interventional studies to prevent contrast-induced nephropathy (CIN), however, there are limited data on comparing either or both, with background of standard intravenous saline hydration versus the standard intravenous saline hydration alone in preventing CIN. Methods : We ...
Zatonska Katarzyna - - 2012
Purpose: The aim of the study was to assess the content of specific fatty acids in the diet and adipose tissue in a selected group of inhabitants of Lower Silesia in Poland. Methods: The study group consisted of 95 inhabitants of Wroclaw and surrounding villages (22 men and 23 women ...
Lader Ellis - - 2012
QUESTION In high-risk patients with dysglycemia, do n-3 fatty acid supplements reduce risk for cardiovascular (CV) events? METHODS DESIGN Randomized, 2 x 2 factorial, placebo-controlled trial (Outcome Reduction with an Initial Glargine Intervention [ORIGIN] trial). ClinicalTrials.gov NCT00069784. ALLOCATION {Concealed}*.† BLINDING Blinded† (patients, {health care providers, data collectors}‡, and event adjudication ...
Misra Amita - - 2012
CYPs have major role in the biosynthesis and modification of secondary metabolites. Predicting the possible involvement of CYPs in secondary metabolism, 20 partial sequences were amplified from the cDNA of trichome enriched tissue of Artemisia annua. Seven CYPs were converted to full length and assigned to different families based on ...
Latocha Piotr - - 2012
BACKGROUND: Hardy kiwifruit (Actinidia arguta) is a new species, commercially grown in recent years. Total phenolics (TPC), vitamin C (TAA) content, antioxidant activity (AA) and their year-to-year variability in seven hardy kiwifruit clones were evaluated. TPC was determined using the Folin-Ciocalteu reagent assay. TAA was estimated by determination of l-ascorbic ...
Jackwood Daral J - - 2012
Nucleotide and predicted amino acid sequences of the infectious bursal disease virus (IBDV) surface protein VP2 have been used to identify strains of the virus and place them into phylogenetic groups. The amino acids across the hypervariable sequence region of VP2 (hvVP2) vary, but typically variant viruses have amino acids ...
Salehi-Pourmehr Hanieh - - 2012
Preeclampsia is one of the main causes of maternal and fetal mortality. Despite numerous studies, its etiology is unknown. Recently there has been attention towards Folic acid. This study examined the association of Folic acid consumption and its serum levels with Preeclampsia. A case-control study conducted in Tabriz- Alzahra hospital. ...
Martín-Ortíz Mamen - - 2012
Nucleobases team up: The efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having MC bonds (M=Ir(III) , Rh(III) ) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.
Vervacke Céline - - 2012
Here we demonstrate the fabrication, characterization and tailoring of porous organic nanomembranes and their direct integration on inorganic substrates for sensing applications. The chemically prepared nanomembranes can be integrated on both conducting and insulating substrates by either transfer or direct synthesis. We also successfully demonstrate their use for the detection ...
van Rossem Lenie - - 2012
Breastfed individuals have a lower blood pressure than formula-fed individuals. Supplementation with n-3 long-chain polyunsaturated fatty acids in adults is also associated with a lower blood pressure. We studied whether children receiving human milk with a relatively high content of n-3 long-chain polyunsaturated fatty acids have a lower blood pressure ...
Zhou Yirong - - 2012
A series of stable C(1)-symmetric chiral diamines () were conveniently synthesized by condensing exo-(-)-bornylamine or (+)-(1S,2S,5R)-menthylamine with various commercially available Cbz-protected amino acids. Among them, can efficiently promote the Michael addition of nitroalkanes to a broad scope of enones with high yields (up to 96%) and excellent enantioselectivities (up to ...
Smith Caren E - - 2012
Low density lipoprotein related receptor protein 1 (LRP1) is a multi-functional endocytic receptor that is highly expressed in adipocytes and the hypothalamus. Animal models and in vitro studies support a role for LRP1 in adipocyte metabolism and leptin signaling, but genetic polymorphisms have not been evaluated for obesity in people. ...
Metherel Adam H - - 2012
Fatty acid profiling through the rapid analysis of capillary blood collected by fingertip prick could enable economical screening for omega-3 polyunsaturated fatty acid (PUFA) status, although the typical requirement of fasting prior to sample collection may limit application. We hypothesize that moderate changes in omega-3 biomarkers determined from fingertip-prick blood ...
Srirekha A A Department of Conservative Dentistry and Endodontics, The Oxford Dental College and Hospital, Bangalore, - - 2013
This study evaluated the removal of debris and smear layer after post space preparation using different irrigations and passive ultrasonic agitation. Sixty human premolars were decoronated and post space prepared after endodontic therapy. The samples were then randomly divided into three experimental groups (Groups A, B, C) and one control ...
McNally S - - 2012
This study reports recent trends in periconceptional folic acid use in Ireland using archived data from Growing Up in Ireland--the National Longitudinal Study of Children. Of a sample of 10,891 mothers, 6,936 (64%) reported taking folic acid before conception and 10,157 (93%) reported taking folic acid during the first trimester ...
Vázquez-Román Sara S Department of Neonatology, Hospital 12 de Octubre, Madrid, Spain. - - 2013
Dornic acidity may be an indirect measurement of milk's bacteria content and its quality. There are no uniform criteria among different human milk banks on milk acceptance criteria. The main aim of this study is to report the correlation between Dornic acidity and bacterial growth in donor milk in order ...
Mollica Adriano - - 2012
A new synthetic pathway is described to prepare asymmetrically protected 2,7-diaminosuberic acid. This strategy exploits (acyloxy)alkoxy promoiety as protecting group and RCM reaction using second generation Grubbs catalyst and provides the trans isomer of (2R,7R)-7-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(tert-butoxycarbonylamino)-8-methoxy-8-oxooct-4-enoic acid, which was in turn reduced to obtain (2R,7R)-7-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(tert-butoxycarbonylamino)-8-methoxy-8-oxooctanoic acid.
Man Jianmin - - 2012
High-amylose cereal starch has a great benefit on human health. Acid modification is very helpful for application of high-amylose starch in food and non-food industries. In this study, the ordered structure of acid-modified high-amylose rice starch was investigated by GPC, HPAEC, (13)C CP/MAS NMR and XRD. Acid preferentially degraded the ...
Arenas-Valgañón Jorge - - 2012
Taurine (2-aminoethanesulphonic acid) is an amino acid-like-compound widely used as an ingredient in some nutraceuticals and energy drinks. Here the interaction of taurine (Tau) with nitrite was investigated. The reactions were carried out mimicking the conditions of the stomach lumen. The conclusions drawn are as follows: (i) Nitrite showed nitrosating ...
Petrillo Daniel E - - 2012
Fmoc-O-benzyl-l-phosphoserine is an important building block in the synthesis of Forigerimod, a phosphopeptide being investigated for Systemic Lupus Erythematosus (SLE). An efficient one-pot process was developed using inexpensive, readily available starting materials. This general procedure was used to prepare a variety of protected phosphoamino acids.
Harrison Fiona Edith - - 2012
[This corrects the article on p. e35623 in vol. 7.].
Kurashina Yusuke - - 2012
The protected stereoisomer of a trihydroxy unsaturated fatty acid, which could be employed as a potential nigricanoside α-chain building block, was synthesized by using Evans asymmetric alkylation, Sharpless kinetic resolution, and diastereoselective reduction as the key steps.
Weng Yi-Chun - - 2012
Caffeic acid phenyl ester is distributed wildly in nature and has antidiabetic and cardiovascular protective effects. However, rapid decomposition by esterase leads to its low bioavailability in vivo. In this study, chronic metabolic and cardiovascular effects of oral caffeic acid phenylethyl amide, whose structure is similar to caffeic acid phenyl ...
Anai Toyoaki - - 2012
Palmitic acid is the most abundant (approx. 11% of total fatty acids) saturated fatty acid in conventional soybean seed oil. Increasing the saturated acid content of soybean oil improves its oxidative stability and plasticity. We have developed three soybean mutants with high palmitic acid content by X-ray irradiation. In this ...
Choy C Anela - - 2012
The δ(15)N values of organisms are commonly used across diverse ecosystems to estimate trophic position and infer trophic connectivity. We undertook a novel cross-basin comparison of trophic position in two ecologically well-characterized and different groups of dominant mid-water fish consumers using amino acid nitrogen isotope compositions. We found that trophic ...
Jiang Tianyi - - 2012
NAD-independent L-lactate dehydrogenase (L-iLDH) from Pseudomonas stutzeri SDM can potentially be used for the kinetic resolution of small aliphatic 2-hydroxycarboxylic acids. However, this enzyme showed rather low activity towards aromatic 2-hydroxycarboxylic acids. Val-108 of L-iLDH was changed to Ala by rationally site-directed mutagenesis. The L-iLDH mutant exhibited much higher activity ...
Martemucci Giovanni - - 2012
Milk contains numerous nutrients. The content of n-3 fatty acids, the n-6/n-3 ratio, and short- and medium-chain fatty acids may promote positive health effects. In Western societies, cow's milk fat is perceived as a risk factor for health because it is a source of a high fraction of saturated fatty ...
Xue Zhangwei - - 2012
Lactic acid has been identified as one of the top 30 potential building-block chemicals from biomass. Therefore, the search for cheap raw materials is an objective to reduce the production costs. Efficient polymer-grade L-lactic acid production was achieved in this report by a thermophilic strain Bacillus sp. XZL4 using corn ...
Falkinham Joseph O JO - - 2011
The anti-mycobacterial activities of nine series of dicarboxyl and tricarboxyl dendritic amphiphiles with one alkyl, two alkyl, and cholestanyl tails against Mycobacterium abscessus, Mycobacterium avium, Mycobacterium chelonae, Mycobacterium marinum and Mycobacterium smegmatis have been measured. The dendritic amphiphiles overcame the limited aqueous solubility of natural long-chain fatty acids, alcohols, and ...
Tepsic Jasna - - 2013
Abstract Research on possible physiological changes as a consequence of a specific lifestyle and long-term strenuous exercise in boxing has been sparse. We determined plasma and erythrocyte phospholipid (PL) fatty acids (FA) profile of 16 elite amateur male boxers (22.4±3.3 years of age), and compared them with a control group ...
Castro-Chavez Fernando - - 2011
My previous theoretical research shows that the rotating circular genetic code is a viable tool to make easier to distinguish the rules of variation applied to the amino acid exchange; it presents a precise and positional bio-mathematical balance of codons, according to the amino acids they codify. Here, I demonstrate ...
Yokoyama Kazumasa - - 2012
Amino acid substitutions at position 89 or 91 in GyrA of fluoroquinolone-resistant Mycobacterium leprae clinical isolates have been reported. In contrast, those at position 94 in M. tuberculosis, equivalent to position 95 in M. leprae, have been identified most frequently. To verify the possible contribution of amino acid substitutions at ...
< 1 2 3 4 5 6 7 8 9 10 11 >