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Canibe N N Department of Animal Science, Faculty of Science and Technology, University of Aarhus, Tjele, - - 2013
To (i) measure the aerobic stability- and describe the characteristics, during aeration, of high-moisture maize (HMM) treated with various additives, and (ii) describe the microbial characteristics of fermented liquid feed (FLF) added HMM. Four treatments were prepared with each of three HMM samples: (i) The HMM as is (CONTROL); and ...
Amiano P P Public Health Department of Gipuzkoa, Government of the Basque Country, and BioDonostia Research Institute, San Sebastian, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), Madrid, Spain. Electronic address: - - 2013
The evidence about the benefits of omega-3 fatty acid intake on coronary heart disease (CHD) is not consistent. We thus aimed to assess the relation between dietary intake of total omega-3 fatty acids (from plant and marine foods) and marine polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid ...
Su Yu-Chih YC Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, 80708, - - 2013
Here we report efficient and selective post-synthesis labeling strategies, based on advanced phosphoramidation reaction, for nucleic acids of either synthetic or enzyme-catalyzed origin. The reactions provided phosphorimidazolide intermediates of DNA or RNA which, whether reacted in one pot (one-step) or purified (two-step), were directly or indirectly phosphoramidated with label molecules. ...
Harris William S WS Sanford School of Medicine, University of South Dakota and OmegaQuant Analytics, LLC, Sioux Falls, SD, USA; Health Diagnostic Laboratory, Inc., Richmond, VA 23219, USA. Electronic address: - - 2013
The Omega-3 Index [red blood cell (RBC) content of eicosapentaenoic acid (EPA)+docosahexaenoic acid (DHA)] is inversely related to risk of cardiovascular disease in humans. In the U.S., the average Omega-3 Index is about 4-6% of RBC fatty acids, whereas in Japan it is 9-10%. The range of physiologically-possible levels for ...
Mita Tsuyoshi - - 2013
In the presence of CsF, a wide range of α-substituted α-siloxy silanes were carboxylated under a CO2 atmosphere (1 atm) via Brook rearrangement. A variety of α-substituents including aryl, alkenyl, and alkyl groups were tolerated to afford α-hydroxy acids in moderate-to-high yields. One-pot synthesis from aldehydes using PhMe2SiLi and CO2 ...
Chen Jun J State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, - - 2014
Premna microphylla turcz leaves (PMTL) have been used for preparing a "green tofu" by Chinese for a long history. Chemical composition analysis indicated alcohol insoluble solids (AIS) of PMTL contained high amount of pectin. Water, ammonium oxalate, hydrochloric acid and sodium hydroxide were used to extract different pectic fractions sequentially. ...
Ghil Lee-Jin - - 2013
Most sulfonic acid based-membranes come to the limit because of high cost and low performance at low relative humidity (RH). Therefore, we synthesized phosphonic acid functionalized polyaniline (PA-PANI). PANI was used as polymer back bone because of excellent chemical mechanical stability and easy synthesis from relatively cheap monomer, and phosphonic ...
Street J J Welsh Transplantation and Immunogenetics Laboratory, Welsh Blood Service, Pontyclun, - - 2013
HLA-A*26:92 differs from A*26:01:01 by seven bases in exon 2 resulting in six amino acid substitutions.
Hansen Camilla P - - 2013
Previous studies have suggested that the intake of trans-fatty acids (TFA) plays a role in the development of obesity. The proportions of adipose tissue fatty acids not synthesised endogenously in humans, such as TFA, usually correlate well with the dietary intake. Hence, the use of these biomarkers may provide a ...
Street J - - 2013
HLA-A*01:139 differs from A*01:01:01:01 by one nucleotide (383G>C) resulting in an amino acid change of glycine104alanine.
Shrestha Ajaya R - - 2013
A novel 2',4'-BNA/LNA analog bridged by guanidine, termed as guanidine bridged nucleic acid (GuNA), was synthesized and incorporated into oligonucleotides. Thermal stabilities and nuclease resistance of GuNA-modified oligonucleotides were investigated and compared with those of 2',4'-BNA/LNA and natural DNA oligonucleotides. GuNA exhibited interestingly high binding affinity towards complementary ssDNA than ...
Ashour Ahmed - - 2013
Semisynthetic reactions were conducted on oleanolic acid, a common plant-derived oleanane-type triterpene. Ten rationally designed derivatives of oleanolic acid were synthesized based on docking studies and tested for their topoisomerase I and IIα inhibitory activity. Semisynthetic reactions targeted C-3, C-12, C-13, and C-17. Nine of the synthesized compounds were identified ...
Zhu Yingdong - - 2013
Biomarkers of dietary intake are prominent tools in nutritional research. Alkylresorcinol metabolites, 3,5-dihydroxybenzoic acid (3,5-DHBA) and 3-(3,5-dihydroxyphenyl)propanoic acid (3,5-DHPPA), have been proposed as exposure biomarkers of whole-grain (WG) wheat and rye intake. However, the profile of alkylresorcinol metabolites is not fully understood. The aim of this study was to investigate ...
Cecconello Alessandro - - 2013
The preparation of a DNA rotaxane consisting of a circular nucleic acid interlocked, through hybridization, on a nucleic acid axle, and stoppered by two 10 nm-sized Au NPs is described. By the tethering of 5 nm- or 15 nm-sized Au NPs on the ring, the supramolecular structure of the rotaxane ...
Dong Kaiwu K State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032 (P. R. - - 2013
Only the mixture works! Acrylic acid derivatives with CF3 substituents in α or β position were efficiently hydrogenated in the presence of a Rh(I) complex with a chiral secondary phosphine oxide (SPO; see scheme) and an achiral Ph3 P as ligands. The corresponding propanoic acid derivatives were obtained with generally high ...
Munson Erik - - 2013
Assessment of 4056 cytology collections by Cervista HPVHR and APTIMA HPV yielded 88.7% concordance, with increased detection via Cervista in ASC-US and NILM patients (P ≤ 0.02). Both assays detected ≥91.7% of CIN2+. 262 specimens demonstrated luminescence within all three Cervista oligonucleotide mixtures (triple-positive). APTIMA HPV and PCR-based microarray confirmed ...
Ling Yan - - 2013
Evidences show that subclinical chronic inflammation is involved in the pathogenesis of diabetic nephropathy. The aim of this study was to examine the relationship between serum C-reactive protein (CRP), serum uric acid, and albuminuria in Chinese type 2 diabetic patients. A total of 1162 type 2 diabetic patients were recruited. ...
Coppa Mauro M University of Turin, Department of Agricultural, Forest and Food Sciences (DISAFA), Via L. da Vinci 44, Grugliasco, 10095 Turin, Italy. Electronic address: - - 2014
Near (NIR) and medium (MIR) infrared reflectance spectroscopy (IR) predictions of fatty acid (FA) composition, expressed as g/kg of milk or g/100g of FA, on fresh and thawed milk were compared. Two-hundred-and-fifty bulk cow milks, collected from 70 farms in northwest Italy, were scanned by MIR in liquid form and ...
Mowson Andrew M - - 2013
[Mn3]2 and [Mn3]4 supramolecular aggregates of weakly exchange-coupled Mn(III)3 single-molecule magnets (SMMs) with S = 6 have been prepared by carboxylate substitution on [Mn3O(O2CMe)3(mpko)3](+) [mpkoH = methyl(pyridine-2-yl) ketone oxime)] with the dicarboxylic acids α-truxillic acid and fumaric acid, respectively. The method opens up a new approach to Mn3 SMM aggregates ...
Xu Liang - - 2013
Transcription unlocked: A synthetic chemical biology approach involving unlocked nucleic acids was used to dissect the contribution of sugar backbone integrity to the RNA Polymerase II (Pol II) transcription process. An unexpected dominant role for sugar-ring integrity in Pol II transcriptional efficiency and fidelity was revealed.
Lohner Szimonetta - - 2013
This study aimed to investigate polyunsaturated (PUFA) and trans isomeric fatty acid status in schizophrenia patients. Fatty acid composition of plasma phospholipids (PL) and triacylglycerols (TG) was analyzed by gas chromatography in 29 schizophrenia patients and 15 healthy controls. We found no difference in PL n-3 fatty acid status between ...
Tarawneh Amer H - - 2013
Bioassay-guided fractionation of the EtOAc extracts of the epiphytic fungus Emericella nidulans resulted in the isolation of a mixture of two fatty acids. This mixture showed 98% binding affinity to human δ opioid receptor. These two fatty acids were identified as palmitic (PAM), 1, and linoleic acids (LNA), 2, by ...
Zhang Zhongqi - - 2013
A mass spectrometry-based method was developed to measure amino acid substitutions directly in proteins down to 0.001% level. When applied to recombinant proteins expressed in E. coli, monoclonal antibodies expressed in mammalian cells, and human serum albumin purified from three human subjects, the method revealed a large number of amino ...
Thuy-Boun Peter S - - 2013
A protocol for the Pd(II)-catalyzed ortho-C-H alkylation of phenylacetic and benzoic acids using alkylboron reagents is disclosed. Mono-protected amino acid ligands (MPAA) were found to significantly promote reactivity. Both potassium alkyltrifluoroborates and alkylboronic acids were compatible coupling partners. The possibility of a radical alkyl transfer to Pd(II) was also investigated.
Ejje Najwa - - 2013
The recently sequenced genome of the marine actinomycete Salinispora tropica CNB-440 revealed a high frequency of gene clusters which code for the biosynthesis of known and novel secondary metabolites. Of these metabolites, bioinformatics analysis predicted that S. tropica CNB-440 could potentially biosynthesize, as high affinity Fe(iii) ligands, siderophores from the ...
Li Dongxia - - 2013
Protein tyrosine phosphatase 1B (PTP1B) is a non-transmembrane protein tyrosine phosphatase, and has received much attention as a molecular target for the treatment of insulin resistance diseases because of its critical roles in negatively regulating insulin- and leptin-signaling cascades. Six ursane-type triterpenes, 3β-acetoxy-urs-12-ene-28-oic acid (1), pomolic acid-3β-acetate (2), pomolic acid ...
Flynn Timothy Corcoran - - 2013
In this study, the authors sought to determine the molecular weight distribution of three hyaluronic acids-Belotero Balance, Restylane, and Juvéderm Ultra-and their rates of degradation following exposure to hyaluronidase. Lot consistency of Belotero Balance also was analyzed. Three lots of Belotero Balance were analyzed using liquid chromatography techniques. The product ...
Kim Yeon Bok - - 2013
Red-flowered buckwheat (Fagopyrum esculentum) is used in the production of tea, juice, and alcohols after the detoxification of fagopyrin. We investigated the metabolomics and regulatory control of anthocyanin production in red-flowered (Gan-Chao) and white-flowered (Tanno) buckwheat cultivars by using quantitative real-time RT-PCR, gas chromatography time-of-flight mass spectrometry, and high performance ...
Horcada Alberto - - 2013
In the present study, fatty acid and triacylglycerol profiles were used to evaluate the possibility of authenticating Iberian dry-cured sausages according to their label specifications. 42 Commercial brand 'chorizo' and 39 commercial brand 'salchichón' sausages from Iberian pigs were purchased. 36 Samples were labelled Bellota and 45 bore the generic ...
Wei Wen-Ting - - 2013
The content of 10-hydroxy-trans-2-decenoic acid (10-HDA), a marker compound in royal jelly (RJ), is the most important criterion in grading RJ for commercial trade and varies with its origin. To identify the effect of geographical origin on 10-HDA content in RJ, 138 samples were collected from 19 provinces of China ...
Gayatridevi S S Department of Biochemistry, Gulbarga University, Gulbarga, 585 106 - - 2013
Differential expression of catalase isozymes in different genotypes of chickpea resistant genotypes- A1, JG-315, JG-11, WR-315, R1-315, Vijaya, ICCV-15017, GBS-964, GBM-10, and susceptible genotypes- JG-62, MNK, ICCV-08321, ICCV-08311, KW-104, ICCV-08123, ICC-4951, ICC-11322, ICC-08116 for wilt disease caused by Fusarium oxysporum. f. sp. ciceri (Foc) was analyzed. Salicylic acid (SA) and ...
Takeda Tadahiro - - 2013
Chiral bis(guanidino)iminophosphoranes were designed and synthesized as a chiral uncharged organosuperbase catalyst that facilitates activation of less-acidic pro-nucleophiles. The newly developed bis(guanidino)iminophosphorane which possesses the high-est basicity among chiral organocatalysts reported to date was proven to be a superb class of chiral organosuperbase by the reaction of azodicarboxylates with 2-alkyl ...
Hasim Ayshamgul - - 2013
In this study, plasma-free amino acid profiles were used to investigate pre-cancerous cervical intraepithelial neoplasia (CIN) and cervical squamous cell carcinoma (CSCC) metabolic signatures in plasma. Additionally, the diagnostic potential of these profiles was assessed, as well as their ability to provide novel insight into CSCC metabolism and systemic effects. ...
Sun Xiujuan - - 2013
Fluorine-doped carbon blacks as inexpensive, high performance electrocatalysts for acidic oxygen reduction reaction were synthesized. The performance of the optimal catalyst (BP-18F) is close to the level of other reported best non-Pt electrocatalysts in acid, but with superlow H2O2 yield (<0.1%) ever. Their high performance is confirmed by quantum calculations.
Xu Jingyu - - 2013
Glycerolipids of the marine diatom Thalassiosira pseudonana are enriched particularly with eicosapentaenoic acid (EPA), and also with an appreciable level of docosahexaenoic acid (DHA). The present study describes the functional characterization of a type 2 diacylglycerol acyltransferase (DGAT2, EC 2.3.1.20) from T. pseudonana, designated TpDGAT2, which catalyzes the final step of triacylglycerol ...
Chaiittianan Rungsiri - - 2013
Abstract For potential topical administration, we formulated a nanoemulsion containing phenolic constituents of Phyllanthus emblica branch extract. The nanoemulsion has high entrapment efficiency, small particle size, is stable, and can release its main chemical components. Branches of P. emblica were extracted with 50% ethanol (EPE) with 5.4% yield. HPLC analysis ...
Peng Lili - - 2013
In this study, efficient polymer-grade l-lactic acid production was achieved with the strain Bacillus sp. P38 by using cellulosic hydrolysate as the sole carbon source. In fed-batch fermentation, 180gL(-1)l-lactic acid was obtained with a volumetric productivity of 2.4gL(-1)h(-1) and a yield of 0.96gg(-1) total reducing sugars. No d-isomer of lactic ...
Wang Fang - - 2013
Histone deacetylase inhibitors (HDACIs) offer a promising strategy for cancer therapy. The discovery of potent ferulic acid-based HDACIs with hydroxamic acid or 2-aminobenzamide group as zinc binding group was reported. The halogeno-acetanilide was introduced as novel surface recognition moiety (SRM). The majority of title compounds displayed potent HDAC inhibitory activity. ...
Ceruso Mariangela - - 2013
Reaction of cyanuryl fluoride with sulfanilamide or 4-aminoethylbenzenesulfonamide afforded triazinyl-substituted benzenesulfonamides incorporating fluorine, which were further derivatized by reaction with amines, amino alcohols, amino acids or amino acid esters. Inhibition studies of all the human (h) carbonic anhydrase (CA, EC 4.2.1.1) isoforms, hCA I-XIV with these compounds revealed that they ...
Hao Yuanqiang - - 2013
A novel electrochemical active polyaniline (PANI) nanowire was fabricated and utilized for the construction of a highly sensitive and selective electrochemical sensor for hepatitis B virus gene. The uniform PANI nanowire was prepared by the enzymatic polymerization of aniline monomers on the amyloid-like nanofiber (AP nanowire), which was self-assembled from ...
Matković Marija - - 2013
Several new adamantyl and homoadamantyl-substituted [Formula: see text]-hydroxybutyric acids, 2-[2-(1-adamantyl)ethyl]-3-hydroxybutyric acid (2), 2-(3-homoadamantyl)-3-hydroxybutyric acid (3), and 2-(1-homoadamantyl)-3-hydroxybutyric acid (4), analogues of the 2-(1-adamantyl)-3-hydroxybutyric acid (1), have been prepared as mixtures of diastereoisomers using selective reduction of corresponding [Formula: see text]-keto esters or aldol condensation of the corresponding carboxylic acid and ...
Doyle Eva - - 2013
A stereochemically safe high-yielding procedure for linking unprotected as well as protected hydroxycarboxylic acids to chiral secondary alcohols via glycolic acid linker is proposed. L-menthol has been linked with both enantiomers of mandelic, malic, and methoxyphenylacetic acid using bromo- or iodoacetyl group as a precursor of the glycolic acid linker. ...
Beydoun May A - - 2013
Evidence that depressive symptoms are inversely related to n-3 (ω3) fatty acids is growing among United States adults. We assessed whether self-reported depressive symptoms were inversely associated with n-3 fatty acid intakes by using a cross-sectional study in 1746 adults (aged 30-65 y) in Baltimore City, MD (2004-2009). The 20-item ...
Solé Cristina - - 2013
Piece of the (inter)action: The interaction of alkoxides with the sp(2) Bpin (pin=pinacol) moiety in aminoboranes forms the in situ Lewis acid-base adduct [RO(-) →B(OR)2 N(R')2 ] which enables the amino moiety to react as a strong nucleophile with several electrophiles, thus providing amino alcohols, β-enamino esters, and β-hydroxy amides ...
Opperman M - - 2013
Globally the omega-3 (n-3) fatty acid supplement industry is expanding rapidly while consumers are becoming more aware of the health benefits of n-3 fatty acids. Our group conducted a survey in 2009 on 45 commercially available fish oil supplements on the South African market. The aim of the study was ...
Maki Kevin C - - 2013
A novel omega-3 formulation in free fatty acid form (OM3-FFA) has as much as 4-fold greater bioavailability than ethyl ester forms and reduces triglyceride (TG) levels in patients with severe hypertriglyceridemia. This study was designed to evaluate the efficacy of adding OM3-FFA (2 or 4 g/d) to statin therapy for ...
Scholtens Denise M - - 2013
ObjectiveTo characterize metabolites across the range of maternal glucose by comparing metabolomic profiles of mothers with high and low fasting plasma glucose (FPG).Research Design and MethodsWe compared fasting serum from an oral glucose-tolerance test at ∼28 weeks' gestation from 67 Northern European ancestry mothers from the Hyperglycemia and Adverse Pregnancy ...
Takkunen Markus - - 2013
Erythrocyte membrane fatty acid (EMFA) composition is used in the validation of food frequency questionnaires (FFQ) and the evaluation of dietary fat quality. In this cross-sectional study we aimed to investigate associations of diet with EMFA. Altogether, 1,033 randomly selected Finnish men, aged from 47 to 75 years filled in a ...
Zangana Karzan H - - 2013
Three octanuclear phosphonate clusters, formulated as [Ln8(O3P(t)Bu)6(µ3-OH)2(H2O)2(HO(i)Bu)(O2C(t)Bu)12](NH3(i)Pr)2 (Ln = Gd, Dy and Tb), were synthesised by refluxing a mixture of pivalic acid (HO2C(t)Bu), Ln(NO3)3·6H2O, tert-Butyl phosphonic acid (H2O3P(t)Bu) and isopropylamine ((i)PrNH2) in isobutyl alcohol (i)BuOH.
Dutta Subrata - - 2013
Photochemical, nucleic acid-induced reactions, which are controlled by nontoxic red light, are well suit-able for detection of nucleic acids in live cells, since they do not require any additives and can be spatially and temporally regulated. We have recently described the first reaction of this type, in which a phenylse-lenyl ...
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