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Haidari Fatemeh F Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. - - 2014
Dietary fatty acids play a critical role in modulation of airway inflammation in asthma. This study was conducted to compare dietary intakes of essential fatty acids and serum levels of inflammatory factors in asthmatic and healthy adults, and to examine the potential relationship between inflammatory markers and dietary fatty acids. ...
Panda N N Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, 769008, Odisha, - - 2014
Fabrication of nanofibers from wild varieties of silk such as eri and tasar is very promising for tissue engineering application because of the presence of RGD (arginine-glycine-aspartic acid) ligand and high content of hydrophilic amino acids. In this study, the biodegradation of silk fibroin (SF) nanofibers have been studied in ...
Rico Cyren M - - 2014
The implications of engineered nanomaterials on crop productivity and food quality are not yet well understood. The impacts of cerium oxide nanoparticles (nCeO2) on growth and yield attributes and nutritional composition in wheat (Triticum aestivum L.) were examined. Wheat was cultivated to grain production in soil amended with 0, 125, ...
Hevekerl Antje A Thünen-Institute of Agricultural Technology, Bundesallee 50, 38116, Braunschweig, - - 2014
Itaconic acid is mainly produced with the filamentous fungi Aspergillus terreus. An increase in the pH during the production phase of the cultivation resulted in an increase in the itaconic acid concentration. The pH was raised by a single pH shift ranging from pH 4 to 6 or by a ...
Zhu Ru-Yi - - 2014
9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp3)-H and C(sp2)-H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically controlled tri- and tetrasubstituted acrylic acids.
Hussmann Jeffrey A JA Institute for Computational Engineering and Sciences, University of Texas, Austin, TX 78712, USA; Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA. Electronic address: - - 2014
It has been proposed that patterns in the usage of synonymous codons provide evidence that individual tRNA molecules are recycled through the ribosome, translating several occurrences of the same amino acid before diffusing away. The claimed evidence is based on counting the frequency with which pairs of synonymous codons are ...
Bullwinkle Tammy T Department of Microbiology, Ohio State University, Columbus, OH - - 2014
Translation of the genome into functional proteins is critical for cellular life. Accurate protein synthesis relies on proper decoding of mRNAs by the ribosome using aminoacyl-tRNAs. During aminoacyl-tRNA synthesis, stringent substrate discrimination and rigorous product proofreading ensure tRNAs are paired with the correct amino acid, as defined by the rules ...
Béreau Virginie V CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, 31077 Toulouse, - - 2014
Bimetallic Schiff-base Al(3+) complexes bearing ester functions at the periphery of the ligands are shown to be efficient fluorescent chemosensors for picric acid detection. The prominent role of an association between the chemosensor and the picric acid in the detection process is demonstrated. The detection of picric acid in water ...
Patidar Shailesh Kumar SK Salt and Marine Chemicals Discipline, CSIR - Central Salt and Marine Chemicals Research Institute, Bhavnagar 364002, - - 2014
Mixotrophic growth at flask level and, autotrophic-mixotrophic and autotrophic growth in photobioreactor by utilizing CO2/air/flue gas were checked for the isolated strain of Monoraphidium minutum from polluted habitat. Our study confirmed that it is a saturated fatty acid rich (30.92-68.94%) microalga with lower degree of unsaturation oil quality (42.06-103.99) making ...
Raymond Michaël M Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, CP 6128 Station Downtown, Montréal, Québec H3C 3J7 - - 2014
Macrocyclic olefin metathesis has seen advances in the areas of stereochemistry, chemoselectivity, and catalyst stability, but strategies aimed at controlling dilution effects in macrocyclizations are rare. Herein, a protocol to promote macrocyclic olefin metathesis, one of the most common synthetic tools used to prepare macrocycles, at relatively high concentrations (up ...
Liu Tao T Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR - - 2014
In order to control the release of amoxycillin (AM) with lower cytotoxicity and higher activity, ethylene glycol dimethacrylate was used as the cross-linker, and a series of poly(methacrylic acid) (PMAA) nanogels were prepared to load the AM. Then, the morphology, size, in vitro release property, long-term antibacterial performance, cytotoxicity, stability ...
Rajaram Subashini S Department of Pharmaceutics, Swamy Vivekanandha College of Pharmacy, Tiruchengode, Namakkal 637205, Tamilnadu, - - 2014
Bioavailability of rifampicin (RIF) from fixed dose combination (FDC) products remains problematic for effective control of tuberculosis (TB) owing to its degradation in the presence of isoniazid (INH) in the stomach acid environment. Ascorbic acid (ASC) is being added to the dissolution medium as well as the plasma sample as ...
Feng Hongxia H College of Food Science, Northeast Agricultural University, Harbin 150030, - - 2014
To evaluate the effects of extrusion process on the trans fatty acids (TFAs) formation in soybean crude oils, three different extrusion parameters, namely, extrusion temperature (80-160°C), feed moisture (10-26%), and screw speed (100-500 rpm), were carried out. It was found that only five different types of TFAs were detected out using ...
Zhang Zhenzhen Z State Key Laboratory of Natural Medicines, PR China. wbyao@cpu.edu.cn - - 2013
An acidic polysaccharide (SGP-2), with a molecular weight of 1880 kDa, was purified from the defatted whole-plant of Sarcandra glabra (Thunb.) Nakai. SGP-2 is mainly composed of glucose, galactose, mannose, arabinose and galacturonic acid in a molar ratio of 12.19 : 8.68 : 6.03 : 1.00 : 15.24. The primary structure analysis reveals that SGP-2 consists of 1,4-linked ...
Papandreou Christopher - - 2013
PURPOSE: The aim of this study was to examine the relationships between gluteal adipose tissue fatty acids and sleep quality parameters in obese patients with obstructive sleep apnoea syndrome (OSAS). METHODS: Fatty acids were measured by gas chromatography in 63 OSAS patients, and sleep was assessed by polysomnography. RESULTS: Significant ...
Osuji Godson O - - 2012
It is necessary to eliminate linoleic acid and allergenic arachins from peanuts for good health reasons. Virginia-type peanuts, harvested from plots treated with mineral salts combinations that mimic the subunit compositions of glutamate dehydrogenase (GDH) were analyzed for fatty acid and arachin compositions by HPLC and polyacrylamide gel electrophoresis, respectively. ...
Degrandi-Hoffman Gloria - - 2012
Hop (Humulus lupulus L.) beta acids (HBA) were tested for miticidal effects on varroa destructor Anderson and Trueman, a parasitic mite of the honey bee (Apis mellifera L.). When varroa were placed on bees that had topical applications of 1 % HBA, there was 100 % mite mortality. Bee mortality ...
Borrelli Osvaldo - - 2012
OBJECTIVE: To assess and compare the pattern of reflux in a selected population of infants with cow's milk (CM) allergy (CMA) and suspected gastroesophageal reflux disease (GERD) while on dietary exclusion and following challenge with CM. STUDY DESIGN: Seventeen children (median age: 14 months) with a proven diagnosis of CMA ...
Deng Huayun - - 2012
G protein-coupled receptor-35 (GPR35) has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium. Gallic acid and caffeic acids are reported to modulate allergic reactions via unknown mode(s) of action. Here we attempt to elucidate whether both phenolic acids share a common mode of ...
Miyake Yoshihiro - - 2012
Dietary fat exerts numerous complex effects on proinflammatory and immunologic pathways. Several epidemiological studies have examined the relationships between intake of fatty acids and/or foods high in fat and allergic rhinitis, but have provided conflicting findings. The current cross-sectional study investigated such relationships in Japan. Study subjects were 1745 pregnant ...
Kim Jihyun - - 2012
Regional dietary habits and cooking methods affect the prevalence of specific food allergies; therefore, we determined the effects of various pH conditions on major peanut allergens. Peanut kernels were soaked overnight in commercial vinegar (pH 2.3) or acetic acid solutions at pH 1.0, 3.0, or 5.0. Protein extracts from the ...
Siqueira Juliana Menezes - - 2011
The objective of the present study was to estimate the effects of introduction of acetylsalicylic acid solution into peritoneal implants in autologous endometrium as a method for treating endometriosis. Forty adult female rabbits were subdivided into 4 groups of 10 rabbits each, and endometriosis was induced via autotransplantation of endometrial fragments ...
Rowland Steven J SJ Petroleum and Environmental Geochemistry Group, Biogeochemistry Research Centre, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK. - - 2011
The large volumes, acute toxicity, estrogenicity, and antiandrogenicity of process-affected waters accruing in tailings ponds from the operations of the Alberta oil sands industries pose a significant task for environmental reclamation. Synchronous fluorescence spectra (SFS) suggest that oil sands process-affected water (OSPW) may contain aromatic carboxylic acids, which are among ...
White N R - - 2011
The objective of this experiment was to determine if dietary inclusion of fish meal would increase plasma and luteal tissue concentrations of eicosapentaenoic and docosahexaenoic acids. Seventeen nonlactating Angus cows (2 to 8 yr of age) were housed in individual pens and fed a corn silage-based diet for approximately 60 ...
Molina-Hernández Miguel - - 2011
Folic acid is antidepressant, either alone or combined with several antidepressant drugs. However, the antidepressant-like actions of folic acid combined with intra-lateral septal (LSN) infusions of neuropeptide Y (NPY) in the forced swimming test (FST) have not been tested before. Thus, systemic injections of fluoxetine (20.0mg/kg, P<0.05; s.c.) or 17-β ...
Guillaume Dom - - 2011
Argan oil has been used in Morocco as food and applied to the skin for centuries. Virgin argan oil of edible or beauty grade is composed of 99-percent acylglycerides (primarily triglycerides). Fatty acids that compose acylglycerides are principally oleic and linoleic acid, 43-49 percent and 29-36 percent, respectively. Unsaponifiable matter, ...
Achiraman Shanmugam - - 2011
Species-specific chemical signals released through urine, sweat, saliva and feces are involved in communication between animals. Urinary biochemical constituents along with pheromones may contribute to variation across reproductive cycles and facilitate to estrus detection. Hence, the present study was designed to analyze such biochemical profiles, such as proteins, carbohydrates, lipids, ...
Laframboise Alyson J - - 2011
The wild perciform teleost Neogobius melanostomus (the round goby) originated from the Ponto-Caspian region and is now a highly successful invasive species in the Laurentian Great Lakes. Males may attract females into their nests for spawning by releasing reproductive pheromones, and it has been previously shown that reproductive males synthesize ...
Tian Zhen - - 2011
Fatty acid-binding protein 4 (Fabp4) is highly expressed in the secondary decidual zone of mouse decidua and deciduoma and stromal cells under in vitro decidualization. Dtprp, a well-known marker of in vitro decidualization, is diminished by small interfering RNA against Fabp4 and FABP4 inhibitor and stimulated through Fabp4 overexpression.
Porto Brenda Lee Simas - - 2011
Qualitative differentiation between natural and enriched chicken eggs through omega (ω) 3 fatty acid profiles by capillary zone electrophoresis (CZE) under direct UV detection at 200 nm is proposed. The electrolyte background consisted of 12.0 mmol L(-1) tetraborate buffer (pH 9.2) mixed with 12.0 mmol L(-1) Brij 35, 17% acetonitrile ...
Borkar Aditi Narendra - - 2011
Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent. The PR dimer and monomer were simulated separately in 9 M acetic acid (9 M AcOH) solution and water to study the denaturation process ...
Chiabrando Valentina V Dipartimento di Colture Arboree, Facoltà di Agraria, Università degli Studi di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, TO, Italy. Electronic address: - - 2011
The potential of 1-methylcyclopropene for controlling ripening in 'Lateblue' blueberry fruit was explored. After harvest, blueberry fruits were exposed to 1-MCP (0.3 and 0.6μll(-1)). After treatment, samples were stored in air at 0°C for 35days and in a controlled atmosphere (3kPa O2+11kPa CO2) for 60days. Quality parameters were monitored (weight ...
Molatová Z - - 2011
The aim of this study was to examine whether and to what extent the supplementation of feed with a coated or non-coated mixture of fatty acids (caprylic and capric acid) affects broiler chickens experimentally infected with Campylobacter jejuni. The study was carried out using 48 chickens divided into four experimental ...
Berdeaux Olivier - - 2010
The retina is one of the vertebrate tissues with the highest content in polyunsaturated fatty acids (PUFA). A large proportion of retinal phospholipids, especially those found in photoreceptor membranes, are dipolyunsaturated molecular species. Among them, dipolyunsaturated phosphatidylcholine (PC) molecular species are known to contain very-long-chain polyunsaturated fatty acids (VLC-PUFA) from ...
Gupte Renuka R Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, - - 2010
Cyclic phosphatidic acid (CPA) is a naturally occurring analog of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a five-membered ring with the sn-3 phosphate. Here, we describe the synthesis of R-3-CCPA and S-3-CCPA along with their pharmacological properties as inhibitors of lysophospholipase D/autotaxin, agonists of the LPA(5) ...
Petelska Aneta D - - 2011
Monolayers of phosphatidylcholine, fatty acid and amine and binary mixtures phosphatidylcholine-fatty acid or phosphatidylcholine-amine were investigated at the air/water interface. Phosphatidylcholine (lecithin, PC), stearic acid (SA), palmitic acid (PA), decanoic acid (DA) and decylamine (DE) were used to the experiment. The surface tension values of pure and mixed monolayers were ...
Oishi-Tanaka Yumiko - - 2010
A recent study in Molecular Cell (Tsukahara et al., 2010) identifies cyclic phosphatidic acid (CPA) as a naturally occurring PPARgamma antagonist that can be generated from lysophospholipids by signal-dependent activation of phospholipase D2. This endogenous CPA regulates PPARgamma functions required for adipogenesis, glucose homeostasis, and vascular wall biology.
Lee Junghoon - - 2011
Phospholipase D (PLD) is capable of hydrolyzing membrane phospholipids, producing phosphatidic acid. To alter phospholipid profiles in soybean seed, we attenuated PLD enzyme activity by an RNA interference construct using the partial sequence from a soybean PLDα gene. Two transgenic soybean lines were established by particle inflow gun (PIG) bombardment ...
Koeberle Andreas - - 2010
Sertoli cells supply germ cells with nutrients, including highly polyunsaturated fatty acids (hPUFAs), which are essential for testicular function. We have previously reported high expression of lysophosphatidic acid acyltransferase (LPAAT)3 in mature mouse testis and suggested an arachidonoyl-transferase activity to LPA. To investigate the role of LPAAT3 in the storage ...
Yamashita Atsushi - - 2010
GPR55 is a seven-transmembrane G-protein-coupled receptor that has been proposed as a novel type of cannabinoid receptor. Previously, we identified lysophosphatidylinositol (LPI), in particular 2-arachidonoyl-LPI, as an agonist for GPR55. In the present study, we examined whether intracellular phospholipase A1 (DDHD domain containing 1, or DDHD1), previously identified as phosphatidic ...
Rajakumari Sona - - 2010
Triacylglycerol (TAG) hydrolysis, membrane lipid biosynthesis, and lipid turnover are largely interlinked processes. In yeast, TAG is mobilized by three TAG lipases named Tgl3p, Tgl4p, and Tgl5p, which are localized to lipid particles/droplets. These TAG lipases posses a conserved GXSXG motif that is characteristic of hydrolytic enzymes. Here, we demonstrated ...
Sueldo Daniela J - - 2010
*In animals and plants, extracellular ATP exerts its effects by regulating the second messengers Ca(2+), nitric oxide (NO) and reactive oxygen species (ROS). In animals, phospholipid-derived molecules, such as diacylglycerol, phosphatidic acid (PA) and inositol phosphates, have been associated with the extracellular ATP signaling pathway. The involvement of phospholipids in ...
Duclos Richard I RI Jr Center for Drug Discovery, Northeastern University, 116 Mugar Life Sciences Building, 360 Huntington Avenue, Boston, MA 02115, USA. - - 2010
2-O-Arachidonoyl-1-O-stearoyl-sn-glycero-3-phosphocholine was synthesized with carbon-13 enrichment of the three glycerol carbons and the carbonyl of the stearoyl group. Phospholipase A(2) was utilized to give optically pure lyso-PC, and only 3% acyl migration occurred during reacylation with arachidonic acid anhydride. This phospholipid is an important biosynthetic precursor of arachidonic acid metabolites ...
Epand Richard M - - 2009
The beef heart adenine nucleotide carrier protein (Anc) of the inner mitochondrial membrane can be purified in a form stabilized by binding the inhibitor carboxyatractyloside. The protein is copurified with bound lipid. We show for the first time that phosphatidic acid, although a minor component, is one of the lipids ...
Kanzawa Noriyuki - - 2009
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) play various roles in cell-cell and cell-environment interactions. GPI is synthesized in the endoplasmic reticulum (ER) from phosphatidylinositol (PI) through step-wise reactions including transfers of monosaccharides and preassembled GPI is transferred en bloc to proteins. Cellular PI contains mostly diacyl glycerol and unsaturated fatty acid in the ...
Le Guédard Marina - - 2009
In yeast, both phosphatidylinositol and phosphatidylserine are synthesized from cytidine diphosphate-diacylglycerol. Because, as in other eukaryotes, phosphatidylinositol contains more saturated fatty acids than phosphatidylserine (and other phospholipids), it has been hypothesized that either phosphatidylinositol is synthesized from distinct cytidine diphosphate-diacylglycerol molecules, or that, after its synthesis, it is modified by ...
Le Grandois Julie - - 2009
This study is a contribution to the exploration of natural phospholipid (PL) sources rich in long-chain polyunsaturated fatty acids (LC-PUFAs) with nutritional interest. Phosphatidylcholines (PCs) were purified from total lipid extracts of different food matrices, and their molecular species were separated and identified by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS(2)). ...
Marra Carlos A - - 2009
BACKGROUND: The influence of cytoskeletal integrity on fatty-acid (FA) metabolism is an almost unexplored field of biochemical research. This study therefore investigated the influence of cytoskeletal integrity on the incorporation of palmitate and eicosa-8,11,14-trienoate into glycerolipids of Hep G2 human hepatoma cells. MATERIAL/METHODS: Attached cultures and suspended cells were exposed ...
Grando F C C - - 2009
To determine the effects of saturated and unsaturated fatty acids in phosphatidylcholine (PC) on macrophage activity, peritoneal lavage cells were cultured in the presence of phosphatidylcholine rich in saturated or unsaturated fatty acids (sat PC and unsat PC, respectively), both used at concentrations of 32 and 64 microM. The treatment ...
Morita Shin-ya - - 2009
In this work, we developed a novel enzymatic method for measuring phosphatidic acid (PA) in cultured cells. The enzymatic reaction sequence of the method involves hydrolysis of PA to produce glycerol-3-phosphate (G3P), which is then oxidized by G3P oxidase to generate hydrogen peroxide. In the presence of peroxidase, hydrogen peroxide ...
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