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Monreal Carlos M CM a Eastern Cereal and Oilseed Research Centre , Agriculture and Agri-Food Canada , Ottawa , Ontario , - - 2014
Abstract Little is known about the fungal metabolism of nC10 and nC11 fatty acids and their conversion into lipids. A mixed batch culture of soil fungi, T. koningii and P. janthinellum, was grown on undecanoic acid (UDA), a mixture of UDA and potato dextrose broth (UDA+PDB), and PDB alone to ...
Jastrzębowska Kamila K Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, - - 2014
Fungal microorganisms, including the human pathogenic yeast and filamentous fungi, are able to synthesize all proteinogenic amino acids, including nine that are essential for humans. A number of enzymes catalyzing particular steps of human-essential amino acid biosynthesis are fungi specific. Numerous studies have shown that auxotrophic mutants of human pathogenic ...
Zymańczyk-Duda Ewa E Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wrocław, Poland, - - 2014
The application of Rhodospirillum toruloides strain allowed resolving the chemically synthesized racemic mixtures of following chiral aminophosphonic acids: 1-aminoethylphosphonic acid (1), 1-amino-1-iso-propyl-1-phosphonic acid (2), 1-amino-1-phenylmethylphosphonic acid (4) and 1-amino-2-phenylethylphosphonic acid (3). The applied protocols resulted in obtaining pure (R)-1-aminoethylphosphonic acid (100 % of e.e.) and enantiomerically enriched mixtures of other phosphonates ...
Dai Li L School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, PR - - 2014
A series of caffeic acid amides were designed, synthesized, and their synergistic activity with fluconazole against fluconazole-resistant Candida albicans was evaluated in vitro. The title caffeic acid amides 3-30 except 26 exhibited potent activity, and the subsequent SAR study was conducted. Compound 3, 5, 21, and 34c, at a concentration ...
Bukhari Habib S T HS Biozentrum, Universität Basel, Klingelbergstrasse 50/70, 4056 Basel, - - 2014
Fungal fatty acid synthase (fFAS) is a key paradigm for the evolution of complex multienzymes. Its 48 functional domains are embedded in a matrix of scaffolding elements, which comprises almost 50% of the total sequence and determines the emergent multienzymes properties of fFAS. Catalytic domains of fFAS are derived from ...
Khot Mahesh M Institute of Bioinformatics and Biotechnology (IBB),University of Pune, Ganeshkhind, Pune -411007, - - 2014
The study evaluates microbial conversion of coconut oil waste, a major agro-residue in tropical countries, into single cell oil (SCO) feedstock for biodiesel production. Copra cake was used as a low cost renewable substrate without any prior chemical or enzymatic pretreatment for submerged growth of an oleaginous tropical mangrove fungus ...
Du Lin L Institute for Natural Products Applications and Research Technologies, Natural Products Discovery Group, and ‡Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma , 101 Stephenson Parkway, Norman, Oklahoma 73019-5251, United - - 2014
A new chlorinated pentacyclic polyketide, daldinone E (1), was purified from a Daldinia sp. fungal isolate treated with the epigenetic modifier suberoylanilide hydroxamic acid (SAHA). A biosynthetically related epoxide-containing daldinone analogue, 2, was also purified from the same fungus. The structures of both compounds were established by spectroscopic methods, and ...
Oggerin Monike M Centro de Astrobiología (INTA-CSIC), 28850 Torrejón de Ardoz, Madrid, Spain. Electronic address: - - 2014
Río Tinto is an extreme environment located at the core of the Iberian Pyrite Belt (IPB). It is an unusual ecosystem due to its size, constant acidic pH, high concentration of heavy metals and a high level of microbial diversity, mainly eukaryotic. Recently it was described the biomineralization of jarosite ...
Petersen Lene M LM Chemodiversity Group, Department of Systems Biology, Technical University of Denmark, Kongens Lyngby, - - 2014
Four new yanuthone analogs (1-4) were isolated from the filamentous fungus Aspergillus niger. The structures of the new compounds were elucidated on the basis of UHPLC-DAD-HRMS data and one-dimensional and two-dimensional NMR spectroscopy. Labeling studies with (13)C8-6-methylsalicylic acid identified three class I yanuthones originating from the polyketide 6-methylsalicylic acid (yanuthone ...
Aktuganov Gleb G Institute of Biology, Ufa Research Centre of Russian Academy of Sciences, 450054 Ufa, Russia. Electronic address: - - 2014
Antifungal lipopeptides produced by an antagonistic bacterium, Paenibacillus ehimensis strain IB-X-b, were purified and analyzed. The acetone extract of the culture supernatant contained an antifungal amphiphilic fraction stainable with ninhydrin on thin layer chromatography. The fraction was further purified with water-methanol extraction followed by a chromatography on a C18-support. The ...
Rafiqul I S M IS Faculty of Chemical and Natural Resources Engineering, Universiti Malaysia Pahang, 26300, Kuantan, Pahang, Malaysia, - - 2014
Xylose reductase (XR) is an oxidoreductase having potential applications in the production of various specialty products, mainly xylitol. It is important to screen for compounds that can decrease XR activity and consequently can decrease xylitol production. We have identified the byproducts in the hemicellulosic hydrolysate that inhibit XR from Candida ...
Shapaval Volha - - 2014
Fungal production of polyunsaturated fatty acids (PUFAs) is a highly potential approach in biotechnology. Currently the main focus is directed towards screening of hundreds strains in order to select of few potential ones. Thus, a reliable method for screening a high number of strains within a short period of time ...
O'Connor Neil K NK UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, - - 2014
While attempting to improve production of fluoro-iturin A in Bacillus sp. CS93 new mono- and di-fluorinated fengycins were detected in culture supernatants by (19)F NMR and tandem mass spectrometry, after incubation of the bacterium with 3-fluoro-L-tyrosine. The fluorinated amino acid was presumably incorporated in place of one or both of ...
Lu He H Department of Microbiology, Chongqing Medical University, Chongqing 400016, People's Republic of - - 2014
This research aims at isolating and identifying the Gamma linolenic acid producing fungi in the traditional Chinese salt-fermented soybean food, Douchi, from Yongchuan, China. In this study Rhizopus oryzae DR3 was identified as a novel fungal species that produces large amounts of γ-linolenic acid. A full-length cDNA, designated her as ...
Liu Shan S Key Laboratory of Clean Utilization Technology for Renewable Energy in Ministry of Agriculture, College of Engineering, China Agricultural University, Beijing, 100083, People's Republic of - - 2014
Corn stover silage (CSS) was pretreated by Phanerochaete chrysosporium in solid-state fermentation (SSF), to enhance methane production via subsequent anaerobic digestion (AD). Effects of washing of corn stover silage (WCSS) on the lignocellulosic biodegradability in the fungal pretreatment step and on methane production in the AD step were investigated with ...
Maria John K M KM Department of Bioresources and Food Science, Konkuk University, Seoul 143-701, Republic of - - 2015
Time dependent changes of primary (GC-MS), isoflavones (LC-MS) and minerals (ICP-OES) content of fermented soya-chunk were compared with un-fermented (0H) soya-chunk and presented. Results revealed that the amino acid content increased gradually based on the fermentation time; whereas the maltose, sucrose and fructose contents were reduced due to the fungal ...
Lim Siang Hui - - 2014
This study aims to improve the photodynamic properties and biological effectiveness of 151-hydroxypurpurin-7-lactone dimethyl ester (G2), a semisynthetic photosensitiser, for the PDT treatment of cancer. The strategy undertook was by conjugating G2 with aspartic acid and lysine amino acids moieties. The photophysical properties, singlet oxygen generation, distribution coefficiency (Log D ...
Pannkuk Evan L EL Graduate Program of Environmental Science, Arkansas State University, Jonesboro, AR 72467, USA. Electronic address: - - 2014
Pseudogymnoascus destructans is a psychrophilic fungus that infects cutaneous tissues in cave dwelling bats, and it is the causal agent for white nose syndrome (WNS) in North American (NA) bat populations. Geomyces pannorum is a related psychrotolerant keratinolytic species that is rarely a pathogen of mammals. In this study, we ...
Leslie Michael A - - 2014
Breast cancer is attributable to modifiable risk factors including the intake of dietary n-3 polyunsaturated fatty acids (PUFA). A key piece of evidence, yet to be addressed, that would demonstrate a causal relationship between n-3 PUFA and breast cancer, is a dose-dependent effect of n-3 PUFA on tumour outcomes. Thus, ...
Toyoda M M Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, - - 2014
Background:Amino-acid transporters are necessary for the tumour cell growth and survival, and have a crucial role in the development and invasiveness of cancer cells. But, it remains unclear about the prognostic significance of L-type amino-acid transporter 1 (LAT1), system ASC amino-acid transporter-2 (ASCT2), and xCT expression in patients with tongue ...
Saito Kunihiko K Kansai Medical - - 2014
Since the phospholipase B (PLB) was reported as a deacylase of both lecithin and lysolecithin yielding fatty acids and glycerophosphocholine (GPC), there was a question as to whether it is a single enzyme or a mixture of a phospholipase A2 (PLA2) and a lysophospholipase (LPL). We purified the PLB in ...
Pelay-Gimeno Marta - - 2013
Pipecolidepsin A is a head-to-side-chain cyclodepsipeptide isolated from the marine sponge Homophymia lamellosa. This compound shows relevant cytotoxic activity in three human tumour cell lines and has unique structural features, with an abundance of non-proteinogenic residues, including several intriguing amino acids. Although the moieties present in the structure show high ...
Fukumoto Shinya - - 2013
L-type amino acid transporter 1 (LAT1), an isoform of amino acid transport system L, transports branched or aromatic amino acids essential for fundamental cellular activities, such as cellular growth, proliferation and maintenance. LAT1 has recently received attention because of its preferential and upregulated expression in a variety of human tumours ...
Pellegrini Paul A - - 2013
DOTA-linked glutamine analogues with a C6- alkyl and polyethyleneglycol (PEG) chain between the chelating group and the L-glutamine moiety were synthesised and labelled with 67,68Ga using established methods. High yields were achieved for the radiolabelling of the molecules with both radionuclides (>90%), although conversion of the commercially available 67Ga-citrate to ...
Colditz Michael J - - 2012
The importance of the extent of resection for gliomas, and the utility of aminolevulinic acid (ALA) and protoporphyrin IX fluorescence in increasing the extent of resection, has become increasingly evident over the past decade. This review continues from Part 1 and focuses on the biochemical mechanisms by which ALA ingestion ...
Vences-Guzmán Miguel Ángel MÁ Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Av. Universidad s/n, Apdo. Postal 565-A, Cuernavaca, Morelos, CP62210, - - 2013
Ornithine lipids (OLs) are phosphorus-free membrane lipids that are widespread among Gram-negative bacteria. Their basic structure consists of a 3-hydroxy fatty acyl group attached in amide linkage to the α-amino group of ornithine and a second fatty acyl group ester-linked to the 3-hydroxy position of the first fatty acid. It ...
Malekshahi Moghadam A - - 2012
Introduction: Consumption of omega-3 fatty acids can alter the inflammatory response in diabetic patients. This study aimed to determine the effects of omega-3 fatty acid supplementation on the serum levels of C-reactive protein (CRP), interleukin (IL)-2 and tumour necrosis factor-alpha (TNF-α) in type 2 diabetes mellitus patients. Methods: A randomised, ...
Dal Bosco A - - 2012
According to EC regulation 889/08, different European countries should draw up a list of slow-growing strains adapted to an organic system, and in the meantime, provide this information to operators and the European Union commission. Thus, the aim of the present work was to evaluate the effect of poultry genotype ...
Hermans D - - 2012
Campylobacteriosis is the most reported bacterial-mediated gastroenteritic disease in many developed countries. Broiler chickens are a natural host for Campylobacter spp., and contaminated poultry meat products are a major source for transmitting pathogenic Campylobacter strains to humans. Currently, no intervention measure efficiently and effectively controls this pathogen in poultry flocks. ...
Lei Fang - - 2012
The aim of this study was to determine the relationship between the composition and function of gut microbiota. Here, we compared the bacterial compositions and fermentation metabolites of human and chicken gut microbiotas. Results generated by quantitative PCR (qPCR) and 454 pyrosequencing of the 16S rRNA gene V3 region showed ...
Franco D - - 2012
The aim of this research was to make a full study of the meat from Mos-breed roosters (Spanish indigenous chicken). To achieve this purpose, the type of breed (Mos vs. a hybrid line, Sasso T-44) and the effect of finishing treatment in the last month (corn vs. commercial fodder) on ...
Shin D - - 2012
To minimize the amount of n-6 fatty acids in broiler chicken meat, 120 Cobb × Ross male broilers were divided into 6 different groups and fed a basal corn-soybean meal diet containing 5% fat from 5 different lipid sources: 1) a commercial mix of animal and vegetable oil, 2) soybean ...
Sun Tao - - 2012
BACKGROUND: Meat safety and nutrition are major concerns of consumers. The development of distinctive poultry production methods based on locally available natural resources is important. Grasshoppers are rich in important nutrients and occur in dense concentrations in most rangelands of northern China. Foraging chickens could be used to suppress grasshopper ...
Kang Kyung-Il - - 2012
Currently, the aetiology of runting and stunting syndrome (RSS) in chickens is unknown. The impact of RSS on weight gain and microscopic lesions in immunological organs and the duodenum, was investigated in 1-day-old commercial broilers at 12 days following exposure to RSS-contaminated litter. Furthermore, the presence of the viral nucleic ...
Srinivas Rathy - - 2012
Lipids produced by microalgae can be grouped into two categories, storage lipids and structural lipids. Storage lipids are mainly triglycerides (TGs) made of saturated fatty acids; TGs can be transesterified to produce biodiesel. Structural lipids are made of polyunsaturated fatty acids (PUFAs), which are essential nutrients for aquatic animals and ...
Wang Wei - - 2012
We report the enzyme-like reversible amination of four intermediates pertinent to the reductive tricarboxylic acid cycle on a photo-irradiated surface of mineral sphalerite (ZnS). Given its prevalence in the waters of early Earth, we suggest that the mineral-based photochemistry might have catalyzed the homeostasis of prebiotic metabolic systems.
Rossi Paccani Riccardo - - 2012
The N-alkylated indanyliden-pyrroline (NAIP) Schiff base 3 is an unnatural α-amino acid precursor potentially useful for the preparation of semi-synthetic peptides and proteins incorporating charged side-chains whose structure can be modulated via Z/E photoisomerization. Here we report that the heteroallylic protons of 3 lead to partial loss of ethanol accompanied ...
Berstad Paula - - 2012
Fatty acid metabolism is altered in colorectal cancer (CRC). We aimed to investigate incorporation of dietary n-6 and n-3 polyunsaturated fatty acids (PUFAs) into plasma phospholipids (PLs), tumour tissue, and normal mucosa in young CRC patients. We also aimed to study differences in PUFA composition between tumour and normal mucosa, ...
Hamano Y - - 2012
1. The present study was conducted to examine the effects of α-lipoic acid on hypothyroidism-induced negative growth performance and whether α-lipoic acid alleviates acute heat stress in relation to hypothyroid status. 2. Female broiler chickens (14 d-old) were fed diets supplemented with α-lipoic acid (100 mg/kg) and an antithyroid substance, propylthiouracil (200 mg/kg), ...
Song Chao - - 2011
Degradation of perfluorooctanoic acid (PFOA) is of great importance due to its global distribution, persistence and toxicity to bioorganisms. In present study, a composite TiO(2) with multiple wall carbon nano-tubes (MWCNTs) was synthesized using sol-gel method and it was used as photocatalyst to degrade PFOA in water. The prepared composite ...
Hansen Rodney A - - 2011
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) or menhaden oil may reduce inflammatory eicosanoids (prostaglandin E(2), thromboxane B(2), leukotriene B(4), and 11-dehydro thromboxane B(2)), matrix metalloproteinases (MMPs), and blood lactate in dogs with nasal carcinomas receiving radiation therapy. We hypothesized that menhaden oil would reduce inflammation from radiation damage and ...
Liu Yang - - 2011
In this work, graphene (G) and graphene oxide (GO) were utilized to enrich and ionize long-chain fatty acids. All together five long-chain fatty acids were selected as models here, n-dodecanoic acid (C12), n-tetradecanoic acid (C14), n-hexadecanoic acid (C16), n-octadecanoic acid (C18), and n-eicosanoic acid (C20). Due to the large surface ...
Casale M - - 2012
An authentication study of the Italian PDO (protected designation of origin) extra virgin olive oil Chianti Classico was performed; UV-visible (UV-vis), Near-Infrared (NIR) and Mid-Infrared (MIR) spectroscopies were applied to a set of samples representative of the whole Chianti Classico production area. The non-selective signals (fingerprints) provided by the three ...
Zhao Quan - - 2011
When chlorine is applied before or during UV disinfection of bromide-containing water, interactions between chlorine, bromide and UV light are inevitable. Formation of halogenated organic byproducts was studied during medium-pressure UV (MPUV) and chlorine coexposure of phenol, nitrobenzene and benzoic acid and maleic acid, chosen to represent electron-donating aromatics, electron-withdrawing ...
Asami Hiroya - - 2011
We have employed IR-UV double resonance spectroscopy to identify the tautomeric and isomeric structures of uric acid and its monohydrated clusters which are produced by the techniques of laser-desorption and supersonic-jet cooling. The IR spectrum obtained for bare uric acid exhibits four distinct NH stretching transitions assignable to those of ...
Bhushan Ravi - - 2011
Enantioresolution of (R,S)-baclofen was accomplished using a newly synthesized set of three chiral derivatizing reagents (CDRs) having amines [(S)-(-)-α,4-dimethylbenzylamine, (-)-cis-myrtanylamine and (R)-(-)-1-cyclohexylethylamine] as chiral auxiliaries in cyanuric chloride and another set of five CDRs having amino acids (l-Leu, d-Phg, l-Val, l-Met and l-Ala) as chiral auxiliaries. These eight CDRs were ...
Calisto Vânia - - 2011
Benzodiazepines are widely consumed psychiatric pharmaceuticals which are frequently detected in the environment. The environmental persistence and fate of these pharmaceuticals as well as their degradation products is of high relevance and it is, yet, scarcely elucidated. In this study, the relevance of photodegradation processes on the environmental persistence of ...
Pumtang Suricha - - 2011
A well known unique property of polydiacetylenes (PDAs) is the colorimetric response to external stimuli making it one of the most studied conjugated polymers for sensing applications. Here we report the synthesis of a novel series of diacetylene acids from the condensation of pentacosa-10,12-diynylamine (PCDAmine) and dicarboxylic acid or its ...
Meinert Cornelia - - 2011
Proteins of all living organisms including plants, animals, and humans are made up of amino acid monomers that show identical stereochemical l-configuration. Hypotheses for the origin of this symmetry breaking in biomolecules include the absolute asymmetric photochemistry model by which interstellar ultraviolet (UV) circularly polarized light (CPL) induces an enantiomeric ...
Bond Michelle R MR Department of Chemistry, Stanford University , Stanford, CA 94305, United - - 2011
Terminal sialic acid residues often mediate the interactions of cell surface glycoconjugates. Sialic acid-dependent interactions typically exhibit rapid dissociation rates, precluding the use of traditional biological techniques for complex isolation. To stabilize these transient interactions, we employ a targeted photo-cross-linking approach in which a diazirine photo-cross-linker is incorporated into cell ...
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