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Allan L D - - 1996
Cardiac evaluation is an important part of the investigation of a fetus with a diaphragmatic hernia. The heart is displaced by the physical presence of the abdominal contents in the chest, and the flow dynamics within the heart are altered. This can produce secondary diminution of chamber growth, particularly of ...
Chatel D - - 1996
The need for improvement of artificial heart biocompatibility led to the design of new artificial ventricles with biological internal coating and new shapes and sizes. The internal coating of these artificial ventricles is made of a molded single-piece, glutaraldehyde-preserved pericardial sac. The pericardial sac was obtained from the entire intact ...
Cantwell J D - - 1996
A 20-year-old male college sprinter and hurdler was seen for a cardiology assessment because a preseason cardiac evaluation revealed a heart murmur dating back to early childhood. He was asymptomatic.
Thoenes M - - 1996
Recently, a significant activity of inducible nitric oxide synthase (iNOS) has been reported in biopsies from failing hearts due to idiopathic dilated cardiomyopathy (IDC). Thus, a potential pathophysiological role of iNOS in IDC has been stated. In order to investigate, whether iNOS expression is of pathophysiological relevance in human heart ...
Iwanaga M - - 1995
Since people tend to prefer musical tempi ranging from 70 to 100 beats per minute, cyclic physiological response like heart rate is considered on of the factors affected by tempo preference. The present study aimed to examine the relationship between preferred tempi and heart rate. Subjects were instructed to find ...
Wu X - - 1995
Mesoderm induction has been studied in many systems and some of the factors involved have been identified. Although the heart is mesodermal in origin, the molecular basis of heart development is essentially unknown. The Drosophila heart is a simple tubular structure similar to the early heart tube in vertebrates. The ...
Cheng P - - 1995
Cardiolipin is the principal polyglycerophospholipid in the heart. The effect of hypoxia on cardiolipin biosynthesis was investigated in isolated rat hearts perfused in the Langendorff mode. Hearts were pulsed-labeled for 60 min with 0.1 mM [1,(3)-3H]glycerol in Krebs Henseleit buffer saturated with either 95% O2/5% CO2 (control) or 95% N2/5% ...
Schoning P R - - 1995
Gross and microscopic lesions of heart disease in 230 greyhounds were recorded. The most common lesion was endcardiosis, which occurred in 24 (10.4%) of the greyhounds. Other heart lesions included endocardial fibrosis, myocardial necrosis, ossification of the aortic fibrous ring, and abscesses of the right atrium. Although females weighed less ...
Alvarez L - - 1995
The right ventricle was studied in 75 anatomically normal swine hearts, using, in all, nine geometric and volumetric parameters: ventricular-wall thickness, length of the right-ventricular inflow and outflow tracts, and volume of the right-ventricular inflow and outflow tracts. The data for these parameters were compared with previously published patterns for ...
Berntson G G - - 1995
The selection of heart period versus heart rate as a chronotropic metric has been considered from quantitative and statistical perspectives, which have not yielded a universal preference for either metric. In the present paper, we discuss biometric considerations that bear on the selection of the optimal chronotropic metric. Biometric evidence ...
Drysdale T A - - 1994
Cardiac troponin I (troponin Ic) expression is restricted to the heart at all stages of Xenopus development. Whole-mount in situ hybridization and Northern blot analysis indicates that troponin Ic is first expressed in tailbud embryos (stage 28) about the time of the first cytological heart differentiation and about 24 hr ...
van Steenis H G - - 1994
This paper compares two methods to estimate heart rate variability spectra, i.e., the spectrum of counts and the instantaneous heart rate spectrum. Contrary to Fourier techniques based on equidistant sampling of the interbeat intervals, the spectrum of counts and the instantaneous heart rate spectrum are based on non-equidistant sampling: the ...
de Backer G - - 1994
STUDY OBJECTIVE: To identify geographical differences in coronary heart disease (CHD) attack rates in a small urban area and to relate these to indicators of socioeconomic class. DESIGN: CHD attack rates were calculated from data of the Ghent MONICA myocardial infarct register for the period 1983-87. The city of Ghent ...
Hanson C M - - 1994
Heart scores (the arithmetic mean of the QRS durations of the three bipolar limb leads for 10 cycles) and heart weights were determined from five draft type horses and five racing type horses, and evaluated for relationships between heart score and heart size within and between the two different types ...
Shiono M - - 1994
The anatomic constraints and design parameters for a heart prosthesis have not yet been defined in heart transplant recipients (i.e., the population most eligible for total artificial heart implantation). The parameters regarding anatomic constraints were measured in 26 consecutive patients undergoing orthotopic heart transplantation (median body surface area 1.9 m2) ...
Yoshida Y - - 1994
Clinical observations indicate that in heart-lung grafting the heart is less frequently rejected than in heart grafting alone. In addition, our results of allograft experiments indicated that the graft survival period is longer in the former (11.8 +/- 0.8 days versus 6.6 +/- 0.5 days, p < 0.05), suggesting that ...
Smith S C - - 1993
In axolotl embryos homozygous for the cardiac-lethal (c) gene, the heart never begins to beat. Recently, we demonstrated that the c gene affects the heart mesoderm directly, making the latter incapable of responding to normal inductive stimuli. Based on these results, we proposed that a reaction-diffusion mechanism controls the later ...
Griffiths M - - 1993
"Excitement" has often been referred to as the gambler's drug although until recently there was little evidence to substantiate such claims. This study involved the systematic monitoring of the psychophysiology of fruit machine gambling using heart rate measures in 30 adolescent male gamblers. The study was designed to test heart ...
LaFrance S M - - 1993
In the axolotl, Ambystoma mexicanum, a recessive cardiac lethal mutation causes an incomplete differentiation of the myocardium. Mutant hearts do not contain sarcomeric myofibrils nor do they beat. We have previously shown that normal anterior endoderm, medium conditioned by endoderm, or total RNA extracted from endoderm stimulates differentiation of mutant ...
Hoyle C - - 1992
The chick heart tube develops from the fusion of the right and left areas of precardiac mesoderm and in almost all cases loops to the embryo's right-hand side. We have investigated whether any intrinsic difference exists in the right and left areas of precardiac mesoderm, that influences the direction of ...
Shahidi S - - 1992
This paper investigates an alternative approach to the modification of cardiovascular reactivity in healthy Type A adults using contingent (true) and non-contingent (false) heart rate biofeedback. Sixteen Type A and sixteen Type B subjects were either given instructions to compete for heart rate reduction or were given no competitive instructions. ...
Ley R - - 1991
Differences in the magnitude of increases in heart rate during prolonged inhalation of 5% CO2 range from a mean of 25 b/min for a group of eight panic-disorder patients who panicked (Woods, Charney, Goodman, & Heninger, 1988. Archives of General Psychiatry, 45, 43-52) to zero b/min for 16 patients, eight ...
Pauli P - - 1991
In panic disorder bodily sensations appear to play an important role as a trigger for anxiety. In our psychophysiological model of panic attacks we postulate the following vicious circle: individuals with panic attacks perceive even quite small increases in heart rate and interpret these changes as being catastrophic. This elicits ...
Yli-Hankala A - - 1990
The correlation between electroencephalogram (EEG) and instantaneous heart rate was studied in deep isoflurane anaesthesia when the EEG showed a burst-suppression pattern in 15 patients aged 19-39 years. At the onset of EEG burst, the heart rate started to accelerate, and at the onset of suppression it started to decelerate. ...
Dew P A - - 1990
The Utah-100 total artificial heart was initially designed and tested in 1983. General design goals, including improved fit for human application, improved reliability, and elimination of thrombus formation, were identified as improvements over the clinically used Jarvik-7 artificial heart, previously developed at the Institute for Biomedical Engineering, University of Utah. ...
Smith S C - - 1990
We have re-examined some of the factors affecting the induction of heart-forming mesoderm in the axolotl. The formation of functional, rhythmically contracting myocardial tissue was used as an assay. We have found that heart-forming mesoderm is fully induced and capable of completing its developmental repertoire by the end of neurulation. ...
Guo Z G - - 1989
The changes of heart rate (HR) and dP/dtmax elicited by challenging the sensitized heart and by a bolus injection of histamine in the presence of cimetidine were observed. The results showed that cimetidine did not completely inhibit the positive chronotropic effect in cardiac anaphylaxis. The increase in HR elicited by ...
Hatch G M - - 1989
Phosphatidylcholine is the major phospholipid in the mammalian heart. Over 90% of the cardiac phosphatidylcholine is synthesized via the CDP-choline pathway. The rate-limiting step of this pathway is catalyzed by CTP:phosphocholine cytidylyltransferase. Current evidence suggests that phosphatidylcholine biosynthesis in the heart is regulated by the availability of CTP and the ...
Link K M - - 1988
From 3D MR scans, the authors have constructed 2D "silhouettes" that correspond to standard radiographic views of the heart. These images explicitly demonstrate the relationship of the surface anatomy to the internal anatomy of the heart and serve to indicate what chambers contribute to the heart borders seen on radiographs. ...
Wheeldon D R - - 1988
A system that uses a chemical method of cooling has been developed for the storage and transport of heart and heart-lung donor organs. This provides a precisely controlled environmental temperature without the use of ice, with its attendant problems of availability and potential contamination with pathogens. Storage and preservation solutions ...
Szaeó S - - 1988
The authors immunized rabbits with homogenized normal and infarcted human heart muscle. The specific autoantibodies were detected by means of bidimensional complement fixation, passive cutaneous anaphylaxis and double immunodiffusion tests. In the immunological reactions normal and infarcted myocardium extracts containing both sarcoplasmatic and myofibrillar proteins, respectively, were used as antigens. ...
Olson L J - - 1987
In each heart taken from autopsies of 14 men with idiopathic hemochromatosis, the conduction system, atria and 10 sites in the ventricles were histologically graded for stainable iron. Stainable iron was exclusively sarcoplasmic; none was observed in the interstitium. The histologic grade for the same anatomic site varied among hearts ...
Bowman I A - - 1987
Jean-Baptiste Sénac's treatise on the heart is considered a landmark in the history of cardiology. In Traité de la structure du coeur, de son action, et de ses maladies (1749), Sénac dealt systematically with the anatomy, physiology, and pathology of the heart, offering the results of anatomical investigations and postmortem ...
Vasků J - - 1987
The implications of mineralization on the diaphragm of a TAH were highlighted. The problem was discussed from the point of view of time and site of calcifying deposit formation, and individual patterns of calcification as well as the question of the relationship between mineralization processes and thrombogenicity were considered. Attention ...
Galoyan A - - 1986
Data on the endocrine heart--neurosecretory cells of heart, producing coronary-dilatory, metabolically active glycopeptides with physico-chemical and biological properties similar to those of previously discovered cardioactive hypothalamic neurohormones--are summarized. Heart hormones participate in both local and distant regulation of heart metabolism and function. Formation and action of these heart hormones is ...
Yada T - - 1985
Double-hearted embryos were produced by whole-embryo culture of chick embryos which were microsurgically cut through the tissue of the anterior intestinal portal at the 1- to 6-somite developmental stage, at the time when the cardiac primordia have not yet fused in the bulboventricular region. The cultured embryos were removed from ...
Gerlis L M - - 1984
Discrete delicate fibromuscular structures crossing the cavity of the left ventricle were identified on morphological examination in 329 (48%) of 686 hearts from patients of all ages with congenital heart disease, acquired heart disease, or normal hearts. These structures were also present in 151 (95%) of 159 hearts from animals ...
Kapitaniak B - - 1984
The instantaneous heart rate changes were examined in 12 forest workers during following tests: increasing (up to refusal) dynamic load on ergometer, rest in erect position, static load (about 75% of body weight) in erect position. The ECG signal, carrying information on heart rate, was amplified and processed by means ...
Russell D - - 1983
Continuous ECG recording has been carried out for at least 24 h in 27 patients suffering from cluster headache. During the study a total of 84 attacks occurred in 25 of the 27 patients who took part. A computerized analysis of the heart rate changes accompanying attacks showed the following: ...
PetrovskiÄ­ B V - - 1983
A series of models of the artificial heart has been developed for simulating different heart defects including stenosis of the atrioventricular ostium and mitral and tricuspid incompetence. Simulation of ventricular fibrillation is also possible. Repeated perturbation and restoration of artificial heart function are possible in the same animal. These processes ...
Pascoe J P - - 1983
The present experiment was undertaken to assess the ways in which benzodiazepine administration alters heart rate responding during Pavlovian aversive conditioning in the rabbit. Each of three benzodiazepine compounds (chlordiazepoxide, flurazepam, diazepam) reliably attenuated the magnitude of the conditioned bradycardia response as compared to vehicle controls. Lower doses of two ...
Gäde G - - 1983
The hearts of many bivalve and gastropod molluscs are resistant to exposure to hypoxic and anoxic conditions. Glycogen and aspartate are simultaneously fermented leading to the accumulation of alanine, succinate and alanopine/strombine. Lactate is not a major end product of anaerobic metabolism in molluscan hearts. In contrast, vertebrate hearts respond ...
Dillon S - - 1981
A rapid laser scanning system was developed to map the spread of excitation in amphibian and mammalian hearts stained with fluorescent dye. Isochronic maps of conduction were constructed by timing the upstroke of the optical action potential; 128 sites could be scanned in 4 milliseconds. The accuracy of this technique ...
Feuvray D - - 1981
We studied mitochondrial structure and intermediates of fatty acid metabolism in mitochondria isolated from ischemic hearts. By electron microscopy, no structural difference was detected between mitochondria isolated from control hearts and from ischemic hearts receiving glucose as the only substrate. However, major differences were observed in mitochondria obtained from control ...
Ebendal T - - 1981
The dynamics of neurite outgrowth elicited by embryonic chick heart explants in sympathetic, spinal, ciliary and Remak's ganglia were investigated in collagen gel cocultures. Neurites emerged preferentially on the side facing the heart explants even after only 6 h and continued to increase in density and length for the next ...
Tsukerman B M - - 1981
The study is concerned with quantitative mapping of electrocardiographic potentials on the human body surface at various applications of equivalent multipole heart generators. The accuracy or reproduction of the electrical heart field with the application of mobile and immobile dipole and quadrupole generators is compared. The immobile equivalent generator (EG) ...
Epstein M L - - 1980
Electrical recordings from the hearts of both cardiac lethal mutant and normal embryos showed the presence of action potentials conducted over the heart tube. Ionic coupling and gap junctions also were observed in both. These results suggest that the absence of heart function in mutant embryos does not result from ...
Hutchins G M - - 1979
This study was undertaken to evaluate the nature and pathogenesis of malformations of the atrioventricular canal in relation to normal cardiogenesis. Serial histologic sections of normal human embryos and fetuses were made, from which three-dimensional images were reconstructed to show the relationship between the developing heart and its surrounding structures, ...
Rychter Z - - 1979
Controversial criteria for definition and classification of univentricular hearts are discussed from the point of view of proliferation pattern in the wall of heart tube and heart loop stage. The persistence of the primitive diffuse proliferation structure is the condition for the development of univentricular heart in which the morphogenetic ...
Leak L V - - 1978
An in situ heart lung preparation was developed to label lymphatics of the actively beating dog heart with subsequent fixation by vascular perfusion. Immediately after interstitial injections of trypan blue and colloidal carbon, a rich plexus of lymphatic vessels was visualized in the epicardium of the actively beating heart. With ...
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