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Kondo Masatoshi M Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-Ku, Fukuoka City, Fukuoka 812-8582, Japan. Electronic address: - - 2014
To investigate the effect of dual-bolus contrast media injection (dual-CM) on the accuracy of automated right ventricular (RV) segmentation on coronary computed tomography angiography (CCTA). A total of 104 patients with suspected and known coronary artery disease underwent 256-slice CCTA with retrospective electrocardiographic (ECG) gating. The patients were divided into ...
Guérard Nicolas N Novartis Institutes for Biomedical Research, Novartis Pharma AG, Werk Klybeck, Klybeckstrasse 141, WKL.136.176, 4057, Basel, Switzerland, - - 2014
Reduced repolarization reserve and increased transmural dispersion of repolarization (TDR) are known risk factors for Torsade de Pointes development, but less is known about the role of apex-to-base (apicobasal) repolarization in arrhythmogenesis. Three needles were inserted in rabbit left ventricle to record unipolar electrograms from endocardium to epicardium and base ...
Kobayashi Yuhei Y Division of Cardiovascular Medicine, Stanford University Medical - - 2014
Assessment of the coronary microvasculature in the clinical setting is a key issue, given that microvascular dysfunction itself has a predictive value for cardiovascular events. The index of microcirculatory resistance (IMR) is an invasive method of interrogating the microvasculature and provides further insight into the physiology of cardiovascular diseases. It ...
Wong Dennis T L DT Discipline of Medicine, University of Adelaide, Adelaide, Australia, - - 2014
We evaluate whether circumferential strain derived from grid-tagged CMR is a better method for assessing improvement in segmental contractile function after STEMI compared to late gadolinium enhancement (LGE). STEMI patients post primary PCI underwent baseline CMR (day 3) and follow-up (day 90). Cine, grid-tagged and LGE images were acquired. Baseline ...
Chen Xiuyu X Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, 167 Beilishi Road, Xi Cheng District, Beijing, 100037, - - 2014
To investigate the relationship between electrocardiographic (ECG) abnormalities and left ventricular (LV) segmental hypertrophy and myocardial fibrosis assessed by cardiovascular magnetic resonance (CMR) in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy (HCM). 118 asymptomatic or mildly symptomatic patients with HCM were examined with late gadolinium enhancement (LGE) CMR, 12-lead ...
Zeller Tanja T Department of General and Interventional Cardiology, University Heart Center Hamburg, Martinistr. 52, 20246 Hamburg, - - 2014
While cardiac troponin measurements have significantly improved the early diagnosis of myocardial infarction, the timely biomarker-based diagnosis of unstable angina pectoris (UAP) remains a major unmet clinical challenge. The aim of this study was to assess levels of circulating microRNAs (miRNAs) as possible novel biomarkers in patients with UAP. A ...
Varga-Szemes Akos A Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, MCLM 556, Birmingham, AL, 35294-0005, - - 2014
To study the feasibility of a myocardial infarct (MI) quantification method [signal intensity-based percent infarct mapping (SI-PIM)] that is able to evaluate not only the size, but also the density distribution of the MI. In 14 male swine, MI was generated by 90 min of closed-chest balloon occlusion followed by reperfusion. ...
Ather Sameer S Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, 35294, USA, - - 2014
The three softwares, Quantitative Perfusion SPECT (QPS), Emory Cardiac Toolbox, and 4 Dimension-Myocardial SPECT (4DM) are widely used with myocardial perfusion imaging (MPI) to determine perfusion defect size (PDS) and left ventricular (LV) function. There are limited data on the degree of agreement between these methods in quantifying the LV ...
Liao Chung P CP Division of Pediatric Cardiology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, - - 2014
A 2.5-year-old boy presented with frequent hospitalizations due to recurrent respiratory tract infections with dyspnea. A fibromuscular membrane dividing the left atrium with obstruction of left atrial inflow to the left ventricle was documented by two-dimensional transthoracic echocardiography (2DTTE). Live/real time three-dimensional transthoracic echocardiography (3DTTE) provided incremental value over 2DTTE ...
Zhang Yanmin - - 2014
Alterations in ECG QT intervals correlate with the risk of potentially fatal arrhythmias, for which transgenic murine hearts are becoming increasingly useful experimental models. However, QT intervals are poorly defined in murine ECGs. As a consequence, several different techniques have been used to measure murine QT intervals. The present work ...
Ko Sung Min SM Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, 4-12 Hwayang-dong, Gwangjin-gu, Seoul, 143-729, - - 2014
We assessed the diagnostic performance of stress- and rest-dual-energy computed tomography (DECT) and their incremental value when used with coronary CT angiography (CCTA) compared with combined invasive coronary angiography (ICA)/cardiovascular magnetic resonance (CMR) for detecting hemodynamically significant stenosis causing a myocardial perfusion defect. Forty patients (30 men; mean age, 63.4 ± 8.8 years) ...
van de Hoef Tim P TP AMC Heart Center, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The - - 2014
Fractional flow reserve (FFR)-guided coronary revascularization is associated with an unequivocal clinical benefit compared with angiographic guidance. However, the well-documented clinical merit of FFR-guided revascularization has resulted in several misunderstandings as to its diagnostic characteristics. Moreover, it has led to the use of FFR as a gold-standard reference test for ...
Cremer Paul P Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Desk J1-5 9500 Euclid Avenue, Cleveland, OH, 44915, - - 2014
Stress myocardial perfusion imaging (MPI) has a well-established role in improving risk stratification. Recent analyses, compared with older data, suggest that the yield of stress MPI has decreased. In part, this trend relates to testing patients with heterogeneous, but improved, risk factor modification. In this setting, positron emission tomography with ...
Asif I I University of Tennessee, Knoxville, - - 2014
The optimal pre-participation screening strategy in competitive athletes is debated. To evaluate the accuracy of cardiovascular screening in NCAA athletes using a standardized history, physical exam (PE), and electrocardiogram (ECG). Prospective multi-center trial. Competitive US collegiate athletes from 17 schools. 3 284 athletes (56% male; 73% Caucasian; 15% African-American; mean ...
De Vecchis R R Cardiology Unit Presidio Sanitario Intermedio "Elena d'Aosta" Naples, Italy - - - 2014
The use of haematochemical markers of intra-ventricular myocardial strain, known as B-type natriuretic peptides, has been proposed as an initial diagnostic step for early screening programs targeting asymptomatic left ventricular dysfunction (ALVD) in populations of subjects at risk. The diagnostic accuracy of BNP for the identification of ALVD was assessed ...
Lewis Eldrin F EF Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: - - 2014
The objective of this study was to determine the impact of nonfatal cardiovascular (CV) events on changes in health-related quality of life (HRQL). There is limited understanding of the impact of nonfatal CV events on long-term changes in HRQL in survivors of myocardial infarction (MI). The VALIANT (Valsartan In Acute Myocardial ...
Murai Tadashi T Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, - - 2014
Objectives and Background: Increased microvascular resistance may impair hyperemic coronary flow by limiting the maximal and constant vasodilation, resulting in increased fractional flow reserve (FFR) due to the underestimation of the translesional pressure gradient. We examined whether microvascular resistance affects FFR after successful percutaneous coronary intervention (PCI). Methods and Results: ...
Limantoro Ione I Department of Cardiology, Maastricht University Medical Centre, PO Box 5800, Maastricht 6202 AZ, The - - 2014
In patients with atrial fibrillation (AF), echocardiographic tissue velocity imaging (TVI) enables assessment of electrical and structural remodelling by measuring, respectively, the AF cycle length (AFCL-TVI) and the atrial fibrillatory wall motion velocity (AFV-TVI). We investigated the clinical and echocardiographic correlates of atrial remodelling assessed by TVI.METHODS AND RESULTS: We ...
Jastrzebski Marek M First Department of Cardiology, Interventional Electrocardiology and Hypertension, University Hospital, Cracow, - - 2014
An accurate and universal method for diagnosis of biventricular (BiV) capture using a standard 12-lead electrocardiogram (ECG) would be useful for assessment of cardiac resynchronization therapy (CRT) patients. Our objective was to develop and validate such an ECG method for BiV capture diagnosis that would be independent of pacing lead ...
Bussadori Claudio C Pediatric Cardiology and Adult with Congenital Heart Disease Department, IRCCS San Donato Hospital, Milan, - - 2014
The right ventricle (RV) is of lesser importance in acquired heart disease, but its role is of increasing importance in congenital heart disease (CHD). Despite major progress being made, precise measurements of the RV are challenging because of its peculiar anatomical structure that is not adaptable to any planar geometrical ...
Hutchinson Mathew D MD From the Division of Cardiology, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, - - 2014
The readership of this journal is well familiar with the unique challenges associated with mapping and ablation of ventricular arrhythmias (VAs) originating from the outflow tract (OT) region. In light of the broad and spatially complex topography of these structures, an organized approach to evaluating them is of paramount importance.(1) ...
van Duijnhoven Sander Martinus Johannes - - 2014
The non-invasive imaging of matrix metalloproteinases (MMPs) activity in post-ischemic myocardial tissue holds great promise to predict cardiac function post myocardial infarction. Consequently, development of MMP specific molecular imaging probes for non-invasive visualization and quantification of MMP activity is of great interest. A novel and elegant MMP imaging strategy is ...
Wackel Philip P Department of Cardiology at Children's Hospital of Pittsburgh at The University of Pittsburgh Medical Center, Pittsburgh, - - 2014
To use smartphone applications (apps) to measure heart rates during supraventricular tachycardia (SVT) in pediatric patients and compare them with heart rates measured by standard electrocardiogram (ECG). Patients <18 years of age (n = 26) undergoing an electrophysiology study were enrolled. During the study, heart rates were measured at baseline ...
Cobey Frederick C FC Division of Cardiothoracic Anesthesiology and Critical Care Medicine, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina; Department of Anesthesiology, Tufts Medical Center, Boston, - - 2014
Functional mitral regurgitation (FMR) occurs as a consequence of left ventricular remodeling and is an independent predictor of adverse outcome. FMR is assessed qualitatively with two-dimensional echocardiography, but accurate quantitation of the actual degree of mitral valve (MV) coaptation is not possible with this method. We evaluated a novel three-dimensional ...
Abe Naoyuki N 1Department of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, - - 2014
We sought to determine whether serial measurements of oxidative stress levels could serve as a predictive marker for cardiovascular (CV) events in patients with ST-segment elevation myocardial infarction (STEMI). Biological antioxidant potential (BAP) levels were measured at admission and at 6, 12, and 24 months in 69 patients with STEMI. ...
Rost Christian C Medical Park, Bad Wiessee, - - 2014
Identification of viable but dysfunctional myocardium after myocardial infarction is important for management, including the decision for revascularization. Assessment of infarct transmurality (TRM) by late contrast enhancement on magnetic resonance imaging (MRI) is frequently used for this task but has several limitations, particularly its availability. The goal of this study ...
Wever-Pinzon Omar O U.T.A.H. Cardiac Transplant Program, University of Utah Health Sciences Center, Veterans Affairs Medical Center & Intermountain Medical Center, Salt Lake City, - - 2014
We aimed to evaluate the diagnostic accuracy of CCTA for detecting cardiac allograft vasculopathy (CAV) in comparison with conventional coronary angiography (CCAG) alone or with intravascular ultrasound (IVUS). CAV limits long-term survival after heart transplantation, and screening for CAV is performed on annual basis. Coronary Computed Tomography Angiography (CCTA) is ...
Reef V B VB Department of Clinical Studies-New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, - - 2014
Murmurs and arrhythmias are commonly detected in equine athletes. Assessing the relevance of these cardiovascular abnormalities in the performance horse can be challenging. Determining the impact of a cardiovascular disorder on performance, life expectancy, horse and rider or driver safety relative to the owner's future expectations is paramount. A comprehensive ...
Sheikh Nabeel N St. George's University of London, London; University Hospital Lewisham, London, United - - 2014
Recent efforts have focused on improving specificity of the European Society of Cardiology (ESC) criteria for ECG interpretation in athletes. These criteria are derived predominantly from white athletes (WAs) and do not account for the effect of Afro-Caribbean ethnicity or novel research questioning the relevance of several isolated ECG patterns. ...
Wang Wenru W Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, - - 2014
Tools to measure the quality of life of Chinese myocardial infarction (MI) patients in mainland China are small in numbers. For this study, 210 Chinese patients with MI were recruited to examine the psychometric properties of the Chinese Mandarin version of the MacNew Heart Disease questionnaire. Thirty-five participants managed to ...
Galderisi Maurizio M Department of Translational Medical Sciences, Federico II University Hospital, Naples, - - 2014
The non-invasive estimation of left ventricular filling pressures (LVFPs) represents a main goal in the clinical setting. Current recommendations encourage the use of pulsed-wave Tissue Doppler for calculating the ratio between the preload-dependent transmitral E velocity and the average of septal and lateral early diastolic velocities (e') of the mitral ...
Duncan Andra E AE From the Departments of Cardiothoracic Anesthesia, Outcomes Research, and Cardiovascular Medicine, Cleveland Clinic, Cleveland, - - 2014
Evaluation of left ventricular performance improves risk assessment and guides anesthetic decisions. However, the most common echocardiographic measure of myocardial function, the left ventricular ejection fraction (LVEF), has important limitations. LVEF is limited by subjective interpretation that reduces accuracy and reproducibility, and LVEF assesses global function without characterizing regional myocardial ...
de Champlain François - - 2014
ABSTRACTIntroduction:Computerized interpretation of the prehospital electrocardiogram (ECG) is increasingly being used in the basic life support (BLS) ambulance setting to reduce delays to treatment for patients suspected of ST segment elevation myocardial infarction (STEMI).Objectives:To estimate 1) predictive values of computerized prehospital 12-lead ECG interpretation for STEMI and 2) additional on-scene ...
Brunetti Natale Daniele ND Cardiology Department, University of Foggia Foggia - - 2014
Exact quantification of plaque extension during coronary angioplasty (PCI) usually falls on interventional cardiologist (IC). Quantitative coronary stenosis assessment (QCA) may be possibly committed to the radiology technician (RT), who usually supports cath-lab nurse and IC during PCI. We therefore sought to investigate the reliability of QCA performed by RT ...
Osmancik Pavel P Cardiocenter, Department of Cardiology, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady Prague, Czech - - 2014
Right ventricular (RV) mid-septal pacing should have fewer negative effects on left ventricular function compared to apical pacing. However, targeting the mid-septum may be technically challenging since it is usually done with two-dimensional fluoroscopy. The rotation of the heart and various shapes of the RV make it difficult to assess, ...
Orlic Dejan D Clinical Center of Serbia, School of Medicine, Belgrade, - - 2014
Routine thrombus aspiration is proposed to be superior to conventional primary percutaneous coronary intervention (PCI) in terms of improved myocardial perfusion, in patients with ST-segment elevation acute myocardial infarction (STEMI). However, myocardial perfusion after thrombus aspiration has not been evaluated by a quantitative, invasive method. We intend to determine whether ...
Motwani Manish - - 2014
Two-dimensional (2D) perfusion cardiovascular magnetic resonance (CMR) remains limited by a lack of complete myocardial coverage. Three-dimensional (3D) perfusion CMR addresses this limitation and has recently been shown to be clinically feasible. However, the feasibility and potential clinical utility of quantitative 3D perfusion measurements, as already shown with 2D-perfusion CMR ...
Leung Melissa M Department of Cardiology, University of New South Wales, Liverpool Hospital, Liverpool, NSW, - - 2014
Aims: Coronary microvascular function has important diagnostic and prognostic implications but routine assessment is difficult. The index of microcirculatory resistance (IMR) is a reliable but invasive measure. We evaluated whether left ventricular contractile reserve (CR), measured with strain imaging on dobutamine echocardiography (DSE), is a reliable non-invasive measure of coronary ...
Karacavus Seyhan S Department of Nuclear Medicine, Faculty of Medicine, Bozok University, Yozgat, Turkey. - - 2014
Assessment of left ventricular (LV) function in patients with myocardial infarction (MI) provide useful diagnostic and prognostic information. Up to date, single photon emission tomography (SPET), positron emission tomography (PET), multidetector computed tomographic angiography, echocardiography (EC) and magnetic resonance imaging (MRI), have been used to examine LV parameters. However, due ...
Arrebola-Moreno A L AL Cardiology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain; Cardiovascular Sciences Research Centre, St George's University of London, London, United Kingdom. Electronic address: - - 2014
Whilst traditional studies have shown that obese individuals are at a higher risk of cardiovascular events compared to lean subjects, recent studies in patients with acute myocardial infarction (AMI) have suggested that obesity may exert protective effects (the "obesity paradox"). We sought to assess the relationship between body mass index ...
Sugamata Wataru W University of Yamanashi, Department of Internal Medicine II, Yamanashi, - - 2014
Measurement of either flow-mediated endothelium-dependent dilatation (FMD) of the brachial artery, brachial-ankle pulse wave velocity (baPWV), or intima-media thickness (IMT) of the carotid artery is useful for risk assessment of future cardiovascular events. This study examined whether combination of these vascular parameters may have an additive effect on the ability ...
Sakurai Daisuke D Division of Functional Diagnostics, Department of Health Sciences, Osaka University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, - - 2014
The assessment of post-systolic shortening (PSS) by speckle tracking echocardiography allows myocardial ischemic memory imaging. Because the endocardial layer is more vulnerable to ischemia, the assessment of this layer might be useful for detecting ischemic memory. Serial echocardiographic data were acquired from nine dogs with 2 min of coronary occlusion followed ...
Bhan Amit - - 2014
Objectives: To assess the feasibility and accuracy of high frequency speckle tracking echocardiography (STE) in a murine model of myocardial infarction (MI). Background: STE is used clinically to quantify global and regional cardiac function but its application in mice is challenging because of the small cardiac size and rapid heart ...
Wierzbowska-Drabik Karina K Chair and Department of Cardiology, Medical University of Lodz, Kniaziewicza 1/5, 91-347, Lodz, Poland, - - 2014
Speckle tracking echocardiography (STE) is a method of quantitative assessment of myocardial function complementary to ejection fraction and visual evaluation. Standard STE analysis, demands manual tracing of the myocardium whereas automated function imaging (AFI) offers more convenient (based on selection of three points) assessment of longitudinal strain. Nevertheless, feasibility and ...
Henninger Nils N From the Departments of Neurology (N.H., M.A.K., J.Z., M.M., R.P.G.) and Psychiatry (N.H.), University of Massachusetts Medical School, - - 2014
Leukoaraiosis (LA) predominantly affects the subcortical white matter, but mounting evidence suggests an association with cortical microvascular dysfunction and potentially decreased cortical ischemic tolerance. Thus, we sought to assess whether preexisting LA is predictive of the cortical infarct volume after middle cerebral artery branch occlusion and whether it relates to ...
Ladeiras-Lopes Ricardo R Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine of the University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal, - - 2014
Insulin resistance plays a central role in the pathophysiology of metabolic syndrome (MS). Its cardiac deleterious effects are characterized by an increase in fibrous tissue that increases myocardial stiffness and contributes to subclinical left ventricular diastolic dysfunction (LVDD) and heart failure with preserved ejection fraction in patients with MS. In ...
Menafoglio Andrea A Division of Cardiology, Ospedale San Giovanni Bellinzona, Bellinzona, - - 2014
The usefulness and modalities of cardiovascular screening in young athletes remain controversial, particularly concerning the role of 12-lead ECG. One of the reasons refers to the presumed false-positive ECGs requiring additional examinations and higher costs. Our study aimed to assess the total costs and yield of a preparticipation cardiovascular examination ...
Liu Chang C Departments of Cardiovascular Surgery (CL, LN, ZL, BW, GZ, LX, HL), Cardiology (CX, JS), and Computer Tomography (XX, KZ), The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, - - 2014
Although dobutamine stress myocardial contrast echocardiography (DSMCE) has been widely used for the prediction of myocardial functional recovery, dynamic changes that occur at the microcirculatory level during stress have been studied limitedly. The objective of the present study was to use low-dose DSMCE to assess microvascular damage and predict myocardial ...
Bamberg Fabian F Department of Clinical Radiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, Germany; Munich Heart Alliance, Munich, Germany. Electronic address: - - 2014
The aim of this study was to determine the feasibility of computed tomography (CT)-based dynamic myocardial perfusion imaging for the assessment of myocardial ischemia and infarction compared with cardiac magnetic resonance (CMR). Sequential myocardial CT perfusion imaging has emerged as a novel imaging technique for the assessment of myocardial hypoperfusion. ...
McKaigney Conor J CJ Department of Emergency Medicine, Queen's University, Ontario, Canada; Department of Emergency Medicine, Denver Health Medical Center, Denver, CO. Electronic address: - - 2014
Rapid assessment of left ventricular ejection fraction (LVEF) may be critical among emergency department (ED) patients. This study examined the predictive relationship between ED physician performed bedside mitral-valve E-point septal separation (EPSS) measurements to the quantitative, calculated LVEF. We further evaluated the relationship between ED physician visual estimates of global ...
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