Search Results
Results 401 - 450 of 1042
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Rajesh Gopalan Nair - - 2013
Presence of right ventricular (RV) infarction imposes a higher risk of adverse events in inferior wall myocardial infarction (IWMI). In this study, we attempted to correlate various indices of RV function assessed by echocardiography with presence of a proximal right coronary artery (RCA) stenosis in patients with first episode of ...
Six A Jacob - - 2013
The HEART score for the early risk stratification of patients presenting to the emergency department with chest pain contains 5 elements: history, electrocardiogram, age, risk factors, and troponin. It has been validated in The Netherlands. The purpose of this investigation was to perform an external validation of the HEART score ...
Dobson Craig P - - 2013
The QT Variability Index (QTVI) is a non-invasive measure of repolarization lability that has been applied to a wide variety of subjects with cardiovascular disease. It is a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of autonomic nervous system tone. The approach ...
Mehrotra Rahul - - 2013
Assessment of left ventricular systolic function is the commonest and one of the most important indications for performance of echocardiography. It is important for prognostication, determination of treatment plan, for decisions related to expensive device therapies and for assessing response to treatment. The current methods based on two-dimensional echocardiography are ...
Qu Xin-Kai - - 2013
To evaluate the utility of multi-slice computed tomography (MSCT) in assessing acute non-reperfused myocardial infarct size. Seven domestic pigs (mean weight 17.3 ± 1.9 kg) underwent ligation of the distal left anterior descending artery to establish a model of acute myocardial infarction (MI). MSCT and triphenyltetrazolium chloride (TTC) staining were ...
Gaur Sara - - 2013
Coronary CT angiography (CTA) is an established noninvasive method for visualization of coronary artery disease. However, coronary CTA lacks physiological information; thus, it does not permit differentiation of ischemia-causing lesions. Recent advances in computational fluid dynamic techniques applied to standard coronary CTA images allow for computation of fractional flow reserve ...
Bonaca Marc P - - 2013
Rapid diagnosis of acute coronary syndrome is a clinical and operational priority in busy emergency departments (ED). We examined the performance of an investigational troponin I (TnI) assay with 10-100-times greater sensitivity than current commercial assays. Among patients with non-traumatic chest pain enrolled in the BWH-TIMI ED Chest Pain Study, ...
Rubinshtein Ronen R The Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center and the Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, - - 2013
Measurement of the fractional flow reserve (FFR) during invasive coronary angiography is the accepted ''gold standard'' for assessing the functional significance of coronary artery lesions by determination of the characteristics of blood flow proximal and distal to a coronary stenosis during pharmacologically-mediated hyperemia. Abnormal FFR is associated with higher cardiac ...
Erturk Mehmet - - 2013
Isovolumic acceleration (IVA) is a new tissue Doppler parameter in the assessment of systolic function of both left and right ventricles. It remains unaffected with the changes in pre- and afterload within the physiological range. The aim of our study was to assess the effect of mitral stenosis degree, which ...
Su Rui-Juan - - 2013
Ultrasound bio-microscopy was used to measure hemodynamic changes in the left main coronary artery after myocardial infarction (MI), and its usefulness in estimating infarct size was evaluated. MI was induced by left anterior descending artery ligation. Diastolic peak velocity (Vd), mean flow velocity (Vmean) and the velocity-time integral (VTI) were ...
Cavarocchi Nicholas C - - 2013
Venoarterial extracorporeal membrane oxygenation (VA ECMO) has been used for profound cardiogenic shock to bridge to decision, ventricular assist device(s) (VADs), or transplant. To assess ventricular function and volume status along with hemodynamics during ECMO weaning, we developed a standardized weaning protocol, guided by a miniaturized transesophageal echocardiography probe designed ...
de Boer Sanneke P M - - 2013
Aims: The European Collaborative Project on Inflammation and Vascular Wall Remodeling in Atherosclerosis - Intravascular Ultrasound (ATHEROREMO-IVUS) study aims to investigate the relations of genetic profile and novel circulating biomarkers with coronary plaque phenotype and vulnerability as determined by intravascular ultrasound (IVUS). Methods and results: ATHEROREMO-IVUS is a prospective, observational ...
Chowdhury F U - - 2013
To study the prognostic value of rapid-acquisition adenosine stress-rest myocardial perfusion scintigraphy (MPS) on a gamma camera using multipinhole collimation and cadmium-zinc-telluride (CZT) detectors. The secondary aim was to assess the diagnostic accuracy of the technique compared with invasive coronary angiography. Retrospective analysis of 1109 consecutive patients undergoing MPS in ...
Patel Amit R - - 2013
Cardiac computed tomography (CCT) has become an important tool for the anatomic assessment of patients with suspected coronary disease. Its diagnostic accuracy for detecting the presence of underlying coronary artery disease and ability to risk stratify patients are well documented. However, the role of CCT for the physiologic assessment of ...
Arumugam Parthiban - - 2013
IntroductionMyocardial perfusion scintigraphy (MPS) is an established non-invasive technique for the diagnosis and management of patients with suspected or known coronary artery disease. Because of the wealth of prognostic data, MPS single photon emission computed tomography (SPECT) is the most commonly used functional test to detect inducible ischaemia. However, the ...
Carasso Shemy - - 2013
Visual left ventricular (LV) wall motion scoring is well established for the assessment of LV function, yet it is subjective, circumstantial, and relative and requires long training. Quantification of myocardial shortening (strain) using two-dimensional speckle-tracking is potentially less subjective. In this study, quantifiable LV contraction (two-dimensional strain) was prospectively cross-related with wall ...
Corino Valentina D A - - 2013
During atrial fibrillation (AF), cancellation of ventricular activity from atrial electrograms (AEG) is commonly performed by template matching and subtraction (TMS): a running template, built in correspondence of QRSs, is subtracted from the AEG to uncover atrial activity (AA). However, TMS can produce poor cancellation, leaving high-power residues. In this ...
van Hout Gerardus Pj - - 2013
Objective. The aim of this study was to validate admittance based pressure volume (PV) loop measurements for the assessment of cardiac function in a porcine model of chronic myocardial infarction. Background. The traditional PV-loop measurement technique requires hypertonic saline injections for parallel conductance correction prior to signal conversion into volume. ...
Darahim Khaled K Department of Cardiovascular Medicine, Faculty of Medicine, Ain Shams University, - - 2014
Dobutamine stress echocardiography (DSE) is widely used for detection of myocardial viability. The main limitation of DSE is its subjective interpretation. Assessment of mitral annular motion velocities with tissue Doppler imaging is a simple and quantitative measurement. To determine the relationship between myocardial viability and regional systolic mitral annular motion ...
Jellema Laurens-Jan C - - 2013
Abstract Background: The focus during the diagnostic process for patients with acute chest pain is to discriminate patients who can be safely discharged from those who are at risk for an acute coronary syndrome (ACS). In this study the diagnostic value of the clinical examination is compared with laboratory testing ...
Pereira Eulália - - 2013
Cardiac magnetic resonance myocardial perfusion imaging (CMR-MPI) is considered a state-of-the-art non-invasive modality for ischemia detection but its additive value in a multiple-test strategy in patients with suspected coronary artery disease (CAD) is not fully validated. We aimed to evaluate CMR-MPI integration with exercise treadmill test (ETT) for the diagnostic ...
Miyagi Hideki - - 2013
To determine the diagnostic performance and reproducibility of strain assessment with displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance (CMR) in identifying contractile abnormalities in myocardial segments with late gadolinium enhancement (LGE). DENSE CMR was obtained on short-axis planes of the left ventricle (LV) in 24 patients with suspected ...
Hariu Crystal D - - 2013
Determine if plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) correlates with markers of hemodynamically significant patent ductus arteriosus (PDA) in dogs. Ten dogs with PDA and 30 healthy dogs of similar ages. Prospective case series with control population. Dogs with PDA were initially evaluated with thoracic radiographs, transthoracic echocardiography, pulmonary capillary ...
Wang Tom Km TK Auckland City Hospital, Auckland, New - - 2013
Criteria for diagnosing myocardial infarction (MI) after coronary artery bypass grafting (CABG) are controversial. Uncertainties remain around the optimal threshold for biomarker elevation and the need for associated criteria. There are no studies of high-sensitivity troponin (hs-TnT) after CABG. We assessed whether using hs-TnT to define MI after CABG was ...
Koudstaal Stefan - - 2013
Pre-clinical studies aimed at treating ischemic heart disease (i.e. stem cell- and growth factor therapy) often consider restoration of the impaired microvascular circulation as an important treatment goal. However, serial in vivo measurement hereof is often lacking. The purpose of this study was to evaluate the applicability of intracoronary pressure ...
Voulgari Christina C First Department of Propaudeutic Internal Medicine, “Laiko” General Hospital, Athens University Medical School, Greece. - - 2013
The ventricular gradient (VG) as a concept was conceived in the 1930s and its calculation yielded information that was not otherwise obtainable. The VG was not utilized by clinicians at large because it was not easy to understand and its computation time-consuming. The contemporary spatial QRS-T angle is based on ...
Belkacemi Anouar - - 2013
By means of optical coherence tomography (OCT), coronary dimensions can be assessed accurately. However, whether OCT can identify hemodynamic significant coronary lesions as determined by fractional flow reserve (FFR) in patients with an in-stent lesion is not known. Therefore, we tried to assess the predictive value of OCT parameters in ...
Oh Jun-Hyok - - 2013
It was demonstrated that the fractional flow reserve (FFR) with partial balloon obstruction may have implications for assessing viable myocardium. In a different way, the index of microcirculatory resistance (IMR) was introduced as a useful indicator for assessing microvascular function. We evaluated the relationship between the FFR0.8 and the IMR. ...
Won Kyoung Sook KS Department of Nuclear Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, - - 2013
Over the past three decades, radionuclide myocardial perfusion scintigraphy (MPS) has become established as the main functional cardiac imaging technique for ischemic heart disease. It is currently appropriate for all aspects of detecting and managing ischemic heart disease, including diagnosis, risk assessment and stratification, assessment of myocardial viability, and evaluation ...
Ebersberger Ullrich - - 2013
To assess image quality and diagnostic performance of 3.0 Tesla (3T) cardiac magnetic resonance (CMR) myocardial perfusion imaging with a dual radiofrequency source to detect functional relevant coronary artery disease (CAD), using coronary angiography and invasive pressure-derived fractional flow reserve (FFR) as reference standard. We included 116 patients with suspected ...
Tanaka Hirokazu - - 2013
Background: Although the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score is used to characterize coronary anatomy based on 9 anatomic criteria such as lesion location and complexity, the relationship between SYNTAX score and myocardial ischemia has yet to be elucidated. Methods and Results: A total of 158 ...
Wildi Karin - - 2013
Current guidelines require a change (rise and/or fall) in levels of cardiac troponin (cTn) for the diagnosis of acute myocardial infarction (AMI). It is unknown whether absolute or relative changes provide higher accuracy when using high-sensitivity cTnI assays. In a prospective international multicentre study, we assessed the diagnostic accuracy of ...
Correa Raúl - - 2013
This work evaluates the vectorcardiographic dynamic changes in ischemic patients before and during Percutaneous Transluminal Coronary Angioplasty (PTCA). Four QRS-loop parameters were computed in 51 ischemic and 52 healthy subjects with the objective of assessing the vectorcardiographic differences between both groups: maximum vector magnitude (QRSmVM), planar area (QRSPA), maximum distance ...
Liu Kan - - 2013
Coronary steal could develop in patients with chronic coronary artery disease (CAD) with collateral circulation, and adversely affect ventricular function and long-term clinical outcome. Poorly developed collaterals are more prone than well-developed collaterals to withdrawing their blood support to the collateralized myocardium due to higher collateral pathway resistance and lower ...
Hou Yang - - 2013
To evaluate the accuracy of low-dose coronary CTA with iterative reconstruction (IR) in the diagnosis of coronary artery disease (CAD) in patients with suspected CAD. Ninety-six patients with suspected CAD underwent low-dose prospective electrocardiogram-gated coronary CTA, with images reconstructed using IR. Image quality (IQ) of coronary segments were graded on ...
Russell Kristoffer - - 2013
Background: Left ventricular (LV) dyssynchrony reduces myocardial efficiency because work performed by one segment is wasted by stretching other segments. We introduce a novel non-invasive clinical method which quantifies wasted energy as the ratio between work consumed during segmental lengthening (wasted work) divided by work during segmental shortening. Methods: The ...
De Caterina Alberto R - - 2013
To angiographically assess myocardial perfusion in patients with Tako-Tsubo syndrome (TTS) in comparison with control individuals and patients with ST-elevation myocardial infarction (STEMI). Coronary microvascular dysfunction has been proposed as the pathophysiological mechanism underlying TTS. We retrospectively selected consecutive TTS patients showing typical left ventricular (LV) apical dysfunction admitted to ...
Kitada Ryoko - - 2013
The recently introduced pocket-sized portable transthoracic echocardiography (pTTE) is accurate for measurement of cardiac chamber size and function as well as for assessment of valvular regurgitation. This study aimed to compare the diagnostic accuracy of the pocket-sized pTTE with the standard TTE (sTTE) and assess its cost-effectiveness. The use of ...
Chow Kelvin - - 2013
To validate a new saturation recovery single-shot acquisition (SASHA) pulse sequence for T1 mapping and to compare SASHA T1 values in heart failure patients and healthy controls. The SASHA sequence consists of 10 electrocardiogram-triggered single-shot balanced steady-state free precession images in a breath-hold. The first image is acquired without magnetization ...
Gan Li-Ming - - 2013
Myocardial ischemia is recognized as an important mechanism increasing the risk for cardiovascular events in both symptomatic and asymptomatic patients. In addition to obstructive coronary diseases, systemic inflammation, macro- and microvascular function are additional important mechanisms contributing to the ischemic myocardium. Accumulating evidence indicates that coronary flow reserve (CFR) is ...
Uitterdijk Andre - - 2013
Objective To compare heart specific fatty acid binding protein (hFABP) and high sensitive troponin I (hsTnI) via serial measurements to identify early time points to accurately quantify infarct-size and no-reflow in a preclinical swine model of ST-elevated myocardial infarction (STEMI). Background Myocardial necrosis, usually confirmed by hsTnI or TnT, takes ...
Bratis K - - 2013
Recent studies have demonstrated that a detailed knowledge of the extent of angiographic coronary artery disease (CAD) is not a prerequisite for clinical decision making, and the clinical management of patients with CAD is more and more focused towards the identification of myocardial ischemia and the quantification of ischemic burden. ...
Vogel Britta - - 2013
Non-ischaemic heart failure is one of the today's most prevalent cardiovascular disorders. Since modern pharmacotherapy has proved to be very effective in delaying disease progression and preventing death, imaging modalities and molecular biomarkers play an important role in early identification and clinical management as well as risk assessment of patients. ...
Gibbs Bethany Barone - - 2013
Sedentary screen time (watching TV or using a computer) predicts cardiovascular outcomes independently from moderate and vigorous physical activity and could impact left ventricular structure and function through the adverse consequences of sedentary behavior. To determine whether sedentary screen time is associated with measures of left ventricular structure and function. ...
Palamalai Vikram - - 2013
This study evaluated the diagnostic performance of four point-of-care (POC) cardiac troponin I (cTnI) assays compared to a central laboratory cTnI assay for detecting myocardial injury and diagnosing acute myocardial infarction (AMI). Plasma obtained at admission, 3h, and 6h post-admission in 169 patients presenting with symptoms suggestive of acute coronary ...
Brinks Henriette H Department of Cardiovascular Surgery, Swiss Cardiovascular Centre, University Hospital of Bern, Bern, - - 2013
Percutaneous closure of the transapical (TA) access site for large-calibre devices is an unsolved issue. We report the first experimental data on the TA PLUG device for true-percutaneous closure following large apical access for transcatheter aortic valve implantation. The TA PLUG, a self-sealing full-core closure device, was implanted in an ...
Hasanien Amer A - - 2013
Sympathetic hyperactivity is linked with several adverse cardiovascular events in patients with acute coronary syndrome (ACS). Sympathetic activity increases early in the process of ischemia through 2 mechanisms. One originates from the central nervous system and leads to enhanced sympathetic activity. The other mechanism originates at the infarct zone and ...
Bettencourt Nuno N Departments of - - 2013
Cardiovascular magnetic resonance (CMR) myocardial perfusion imaging (MPI) is a state-of-the-art noninvasive modality for detection of myocardial ischemia and coronary artery disease. Magnetic resonance coronary angiography (MRCA) allows visualization of the coronary tree, but its incremental value as part of a CMR protocol including MPI and late gadolinium enhancement (LGE) ...
Jaarsma Caroline - - 2013
Although electrocardiography is frequently used as an initial test to detect or rule out previous myocardial infarction (MI), the diagnostic performance of commonly used electrocardiographic scoring systems is not well described. We aimed to determine the diagnostic accuracy of (1) the Universal Definition, (2) Minnesota ECG Code (MC), (3) Selvester ...
Panagiotou Christos - - 2013
This paper addresses the possibility of detecting presence of scar tissue in the myocardium through the investigation of vectorcardiogram (VCG) characteristics. Scarred myocardium is the result of myocardial infarction (MI) due to ischemia and creates a substrate for the manifestation of fatal arrhythmias. Our efforts are focused on the development ...
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