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Results 301 - 350 of 1042
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Tsai Jang-Zern JZ Department of Electrical Engineering, National Central University, Jhongli City, Taoyuan County, - - 2014
White matter hyperintensities (WMHs) of presumed vascular origin are common in ageing population, especially in patients with acute cerebral infarction and the volume has been reported to be associated with mental impairment and the risk of hemorrhage from antithrombotic agents. WMHs delineation can be computerized to minimize human bias. However, ...
De Smedt Delphine D Department of Public Health, Ghent University, Belgium. Electronic address: - - 2014
The aim of this study was to compare EuroQol five-dimensional (EQ-5D) utility scores and six-dimensional health state classification (SF-6D) utility scores (derived from the 12-Item Short-Form Health Survey [SF-12]) by using a large European sample of patients with stable coronary heart disease. Special attention was given to country-specific results. Data ...
Sharir Rinat R Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel; Laboratory of Cardiovascular Research, Department of Cardiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Ischemic cardiac damage is associated with upregulation of cardiac pro-inflammatory cytokines, as well as invasion of lymphocytes into the heart. Regulatory T cells (Tregs) are known to exert a suppressive effect on several immune cell types. We sought to determine whether the Treg pool is influenced by myocardial damage and ...
Serrano-Ferrer Juan - - 2014
Growing evidence demonstrates subtle left ventricular myocardial dysfunction in patients with metabolic syndrome (MetS), with central obesity, glucose intolerance and inflammation emerging as important contributors. Whether these results can be translated to the right ventricle (RV) is not yet fully elucidated. Furthermore, although lifestyle intervention favorably impacts MetS components and ...
Shuster Jerrica E JE PGY2 Pharmacy Resident, Cardiology Specialty, Clinical - - 2014
Clinical surveillance systems (CSS) are utilized by many health care institutions to help identify at-risk patients, prioritize care, improve the clinical services provided, and increase compliance with the Center for Medicare and Medicaid Services (CMS) core measures. This study will assess the accuracy and practicality of a CMS acute myocardial ...
Van De Heyning Caroline M - - 2013
Two-dimensional transthoracic echocardiography (2DTTE) remains the first-line diagnostic imaging tool to assess primary mitral regurgitation although cardiovascular magnetic resonance (CMR) has proven to establish left ventricular function more accurately and might evaluate mitral regurgitation severity more reliably. We sought to compare routine evaluation of left ventricular function and mitral regurgitation ...
Taylor Richard Andrew RA Department of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519 USA. Electronic address: - - 2013
Pulmonary embolism (PE) is a common emergency department (ED) diagnosis with a wide range in mortality rates. Methods to identify and risk-stratify PE, including measuring right ventricular strain (RVS) by echocardiography (echo), are essential in providing effective and efficient care. A limited echo examination aims to expedite and increase availability ...
Chow Benjamin Jw - - 2013
The prevalence of heart failure (HF) is rising in industrialized and developing countries. Though invasive coronary angiography (ICA) remains the gold standard for anatomical assessment of coronary artery disease in HF patients, alternatives are being sought. Computed tomographic coronary angiography (CTA) has emerged as an accurate non-invasive diagnostic tool for ...
Schmidt Renate R Adult Congenital and Valvular Heart Disease Center, Department of Cardiology and Angiology, University Hospital of Münster, Münster, - - 2013
Patients are commonly affected by ventricular dysfunction and heart failure after Fontan palliation. Reliable quantification of ventricular function is of interest but hampered by complex ventricular anatomy and physiology. We aimed to assess myocardial function using a novel cardiac magnetic resonance imaging (CMR)-based feature-tracking (FT) technique and to study its ...
Zafar Haroon H Tissue Optics & Microcirculation Imaging Facility, National University of Ireland, Galway, Ireland; National Biophotonics & Imaging Platform, Dublin, Ireland. Electronic address: - - 2013
The main objective of this study is to determine the correlation between fractional flow reserve (FFR)- and frequency domain optical coherence tomography (FD-OCT)-measured lumen parameters, and to determine the diagnostic competence of FD-OCT concerning the identification of severe coronary stenosis. A total of 41 coronary stenoses in 30 patients were ...
Sakamoto Fumi F Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Kumamoto, 860-0821, Japan, - - 2013
We assessed the value of combining (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy for the discrimination of dementia with Lewy bodies (DLB) from other types of dementia. We subjected 252 consecutive patients with clinically suspected DLB to both (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy. Patients with Parkinson's ...
Wildgruber Moritz M 1Department of Diagnostic and Interventional Radiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; International Graduate School of Science and Engineering, Technische Universität München, Garching, - - 2013
-To prospectively evaluate an elastin-specific magnetic resonance contrast agent (ESMA) for in-vivo targeting of elastic fibers in myocardial infarction and post-infarction scar remodeling. -Myocardial infarction (MI) was induced in C57BL/6J mice (n=40) by permanent ligation of the left anterior descending coronary artery (LAD). Magnetic Resonance Imaging (MRI) was performed at ...
Mueller Christian C Department of Cardiology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, - - 2013
Biomarkers complement clinical assessment and the 12-lead ECG in the diagnosis, risk stratification, triage, and management of patients with suspected acute coronary syndrome (ACS). While there is broad consensus that cardiac troponin (cTn) I or T is the preferred biomarker in clinical practice, important uncertainties remain regarding the value of ...
Gimelli Alessia A Fondazione Toscana Gabriele Monasterio, Via Moruzzi, 1, 56124 Pisa, - - 2013
To investigate the relationships between regional adrenergic innervation heterogeneity, myocardial perfusion, and contractile function obtained by means of a low-dose imaging protocol with a cadmium-zinc-telluride (CZT) dedicated camera. Twenty-eight patients with or without ischaemic heart disease underwent (123)I-metaiodobenzylguanidine (MIBG) planar scintigraphic and CZT early and delayed evaluations followed by (99m)Tc-tetrofosmin ...
Frederiksen Christian Alcaraz - - 2013
The aim of the study was to compare the diagnostic accuracy of point-of-care cardiac ultrasonography performed by a novice examiner against results from a specialist in cardiology with expert skills in echocardiography, with regard to the assessment of six clinically relevant cardiac conditions in a population of ward patients from ...
Miller Christopher A CA North West Heart Centre and The Transplant Centre, University Hospital of South Manchester, Wythenshawe Hospital, Manchester, UK; Centre for Imaging Sciences & Biomedical Imaging Institute, University of Manchester, UK; Institute of Cardiovascular Sciences, University of Manchester, UK. Electronic address: - - 2013
To evaluate the diagnostic performance of multiparametric cardiovascular magnetic resonance (CMR) for detecting cardiac allograft vasculopathy (CAV) using contemporary invasive epicardial artery and microvascular assessment techniques as reference standards, and to compare the performance of CMR with that of angiography. CAV continues to limit the long-term survival of heart transplant ...
Bohyn Emilie E Medical Emergency Service of Annecy, Annecy Health Center, Pringy, France. Electronic address: - - 2013
High-sensitivity troponin (HS-TnT) combined with copeptin have been proposed to expedite the diagnostic exclusion of acute myocardial infarction. The Global Registry of Acute Coronary Events (GRACE) has been validated and recommended by the European Society of Cardiology as a prognostic score in the management of acute coronary syndrome (ACS) without ...
Mouden Mohamed - - 2013
Coronary artery calcium (CAC) scores influence the pre-test likelihood of ischemia in patients undergoing myocardial perfusion imaging (MPI). We investigated the influence of CAC score knowledge on the visual interpretation of MPI in patients referred for the diagnostic work-up of suspected coronary artery disease. We retrospectively analyzed symptomatic patients who ...
Motiwala Shweta R - - 2013
Myocardial remodeling is pivotal in the progression and complication of chronic heart failure (HF). We assessed serial measurement of five biomarkers with biologic links to remodeling (biglycan, secreted frizzled-related protein 3, endostatin, insulin-like growth factor binding protein 7 [IGFBP7], mimecan) in 142 patients with HF followed through 882 office visits. ...
Kim Kyung-Hee KH Department of Medicine, Seoul National University Hospital, Seoul, Republic of - - 2013
This study sought to determine whether computational modeling can be used to predict the functional outcome of coronary stenting by virtual stenting of ischemia-causing stenoses identified on the pre-treatment model. Computed tomography (CT)-derived fractional flow reserve (FFR) is a novel noninvasive technology that can provide computed (FFRct) using standard coronary ...
van Slochteren Frebus J - - 2013
Local layer-specific myocardial deformation after myocardial infarction (MI) has not been studied extensively although the sub-endocardium is more vulnerable to ischemia and interstitial fibrosis deposition. Radiofrequency (RF) ultrasound-based analysis could provide superior layer-specific radial strain estimation compared with clinically available deformation imaging techniques. In this study, we used RF-based myocardial ...
Snoer Martin - - 2013
Despite revascularization and optimal medical treatment, patients with coronary artery disease (CAD) have reduced exercise capacity. In the absence of coronary artery stenosis, coronary flow reserve (CFR) is a measure of coronary microvascular function, and a marker of future poor outcome in CAD patients. The aim of this study was ...
Mazurek Tomasz - - 2013
Extravascular expression of inflammatory mediators may adversely influence coronary lesion formation and plaque stability through outside-to-inside signaling. It has been also shown, that maximal standardized uptake value (SUV) of 18-fluorodeoxyglucose (FDG) detected by positron emission tomography (PET/CT) is proportional to macrophage density. To investigate, whether inflammatory activity of pericoronary adipose ...
Christenson Eric - - 2013
Cardiac troponin I (cTnI) and T (cTnT) have displaced myoglobin and creatine kinase-MB as the preferred markers of myocardial injury and have become the cornerstones for diagnosis of myocardial infarction (MI). Current guidelines for MI diagnosis give specific recommendations for cTnI and cTnT assays including instructions to reliably measure values ...
Anwar Ashraf M AM Department of Cardiology, King Fahd Armed Forces Hospital, Jeddah, Saudi-Arabia. ; Department of Cardiology, Al-Azhar University, Cairo, - - 2013
Visual assessment of wall motion abnormalities (WMA) by 2-dimensional echocardiography (2DE) is the most semi-quantitative method used to detect coronary artery disease (CAD), but it carries many limitations. Speckle tracking echocardiography (STE) overcomes these limitations and allows an objective quantification of myocardial deformation. The aim of the study to examine ...
Weinsaft Jonathan W - - 2013
Left ventricular (LV) infarct size is a prognostic determinant after acute myocardial infarction (AMI). ECG data have been used to measure infarct size, but conventional approaches use multiparametric algorithms that have limited clinical applicability. This study tested a novel ECG approach - based solely on Q wave area - for ...
Doyle Mark M Allegheny General Hospital, Pittsburgh, PA, - - 2013
To introduce an algorithmic approach to improve the interpretation of myocardial perfusion images in women with suspected myocardial ischemia. Gated single photon emission computed tomography (SPECT) and magnetic resonance (MR) myocardial perfusion imaging (MPI) approaches have relatively poor diagnostic and prognostic value in women with suspected myocardial ischemia. Here we ...
Harms Craig A CA North Carolina State University, College of Veterinary Medicine, Center for Marine Sciences and Technology, Morehead City, NC 28557, USA. - - 2013
Electrocardiography (ECG) was performed on captured free-ranging bottlenose dolphins (Tursiops truncatus) during a health assessment exercise and compared with that of a Navy collection of dolphins habituated to handling out of water in order to assess possible cardiovascular impacts of capture and handling. Six-lead recordings (I, II, III, aVr, aVl, ...
Peer Maya M Department of Internal Medicine, Woltson Medical Center, Holon, - - 2013
Left ventricular hypertrophy (LVH) is recognized as an independent predictor of cardiovascular morbidity and mortality in hypertensive patients. Thus, it is critical to understand the mechanisms underlying the development of LVH for formulation screening and treatment strategies. This study was designed to determine the association between echographically determined LVH measures ...
Pirhan O - - 2013
Aim: Myocardial performance index (MPI) is a well known prognostic parameter in acute myocardial infarction (AMI) patients, which has been used to assess global cardiac functions. In this study, we aimed to evaluate the corelation between the MPI levels obtained by PW doppler and Tissue doppler ultrasonography with reperfusion in ...
Rossi Alexia - - 2013
-Coronary lesions with a diameter narrowing ≥ 50% on visual CT coronary angiography (CTCA) are generally considered for referral to invasive coronary angiography (ICA). However, similarly to ICA, visual CTCA is often inaccurate in detecting functionally significant coronary lesions. We sought to compare the diagnostic performance of quantitative CTCA with ...
Chin Calvin W L - - 2013
To determine the optimal T1 mapping approach to assess myocardial fibrosis at 3T. T1 mapping was performed at 3T using the modified look-locker-inversion sequence in 20 healthy volunteers and 20 patients with aortic stenosis (AS). Pre- and post-contrast myocardial T1, the partition coefficient (λ; ΔRmyocardium/ΔRblood, where ΔR = 1/post-contrast T1 ...
Sharma Abhishek A Department of Medicine, Maimonides Medical Center, Brooklyn, New York. Electronic address: - - 2013
We compare the diagnostic accuracy of multidetector row computed tomography (MDCT) to cardiac magnetic resonance imaging (CMR) for evaluating global left ventricular function. We systematically searched PubMed, CINAHL, Cochrane CENTRAL, Scopus, and the Web of Science databases for studies published between 1966 to January 2013 that compared left ventricle (LV) ...
Jacquier Alexis A Department of Radiology, Aix Marseille Université, Hôpital Universitaire la Timone, Marseille, France; Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR CNRS n° 6612, Aix Marseille Université, Faculté de Médecine de Marseille, Marseille, - - 2013
1) To assess the myocardial partition coefficient (λ) of gadolinium quantified using T1 mapping in dilated cardiomyopathy (DCM); and 2) to assess the impact of increased λ on left ventricular (LV) circumferential strain and ejection fraction in DCM. Seventeen patients with DCM and 11 controls were prospectively included. All patients ...
van Rosendael Philippe J - - 2013
Aims: To assess the left atrial appendage (LAA) geometry with multidetector-row computed tomography (MDCT) and its implications for selection of closure devices. Methods and results: One hundred and ninety-seven patients who underwent MDCT prior to catheter ablation for atrial fibrillation were evaluated. Feasibility for Watchman and Amplatzer Cardiac Plug (ACP) ...
Biere Loïc L L'UNAM Université, Angers, France; Université d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. Electronic address: - - 2013
To describe the time course of myocardial scarring after transapical-transcatheter aortic valve implantation (TA-TAVI) with the Edwards SAPIEN XT™ and the Edwards SAPIEN™ prosthesis in a 3-month follow-up study using cardiac magnetic resonance imaging (CMR). In 20 TA-TAVI patients, CMR was performed at discharge and 3 months (3M). Cine-MRI was ...
Bauer M - - 2013
Synthetic patch materials currently in use have major limitations, such as high susceptibility to infections and lack of contractility. Biological grafts are a novel approach to overcome these limitations, but do not always offer sufficient mechanical durability in early stages after implantation. Therefore, a stabilising structure based on resorbable magnesium ...
Sundh Frida F Department of Clinical Physiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Duke Clinical Research Institute, Durham, North Carolina, - - 2013
Electrocardiographic (ECG) Selvester QRS score criteria with false indication of anteroseptal scarring consistent with myocardial infarction have been found in patients with ostium secundum atrial septal defect (OS-ASD). The objective of this study was to evaluate ECGs pre and post percutaneous transcatheter OS-ASD closure to test the hypothesis that the ...
Agostinelli Angela - - 2013
T-wave offset (Toff) identification may be jeopardized by the presence of a significant inter-method (IMV) and inter-lead (ILV) Toff variability. Thus, the aim of the present study was to investigate if the dominant T wave (DTW) may be used to enhance Toff-identification reliability. DTWs and 15-lead ECG T waves of ...
Kurisu Satoshi - - 2013
Recent studies have shown good correlations between echocardiography and Tl-201 gated single-photon emission computed tomography (SPECT) for the assessment of left ventricular volumes and ejection fraction. We assessed how left ventricular geometry affected correlations between these values measured by the 2 methods in patients with known or suspected coronary artery ...
Cullen Louise - - 2013
Risk stratification processes for patients with possible acute coronary syndrome (ACS) recommend the use of serial sensitive troponin testing over at least 6h. Troponin assays vary in their analytical performance. Utility in accurate risk stratification at 2h post-presentation is unknown. A diagnostic accuracy study of patients presenting to the emergency ...
Rochitte Carlos E - - 2013
To evaluate the diagnostic power of integrating the results of computed tomography angiography (CTA) and CT myocardial perfusion (CTP) to identify coronary artery disease (CAD) defined as a flow limiting coronary artery stenosis causing a perfusion defect by single photon emission computed tomography (SPECT). We conducted a multicentre study to ...
Parlak Ismail Burak - - 2013
The existence of a right-to-left shunt may increase the likelihood of micro-embolism by allowing a flux of bubbles under hyperbaric conditions. The aim of the study was to measure the relationship between these shunts and bubbles in 10 consecutive subjects using trans-thoracic and trans-esophageal echocardiography. In video frames, all cardiac ...
McCabe James M - - 2013
For patients who undergo primary percutaneous coronary intervention (PCI) for ST-segment-elevation myocardial infarction, the door-to-balloon time is an important performance measure reported to the Centers for Medicare & Medicaid Services (CMS) and tied to hospital quality assessment and reimbursement. We sought to assess the use and impact of exclusion criteria ...
Opolski Maksymilian P - - 2013
The widespread clinical application of coronary computed tomography angiography (CCTA) has resulted in increased referral patterns of patients with intermediate coronary stenoses to invasive coronary angiography. We evaluated the application of advanced quantitative coronary angiography (A-QCA) for predicting fractional flow reserve (FFR) in intermediate coronary lesions detected on CCTA. Fifty-six ...
Abelin Anibal P - - 2013
Comparisons between dedicated risk scores in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) in real-world clinical practice are scarce. The aim of this study was to assess the diagnostic performance of the Global Registry of Acute Coronary Events (GRACE), Primary Angioplasty in Myocardial Infarction ...
Abidov Aiden - - 2013
Gated myocardial perfusion SPECT (GSPECT) is a major clinical tool, widely used for performing myocardial perfusion imaging procedures. In this review, we have presented the fundamentals of GSPECT and the ways in which the functional measurements it provides have contributed to the emergence of myocardial perfusion SPECT in its important ...
Li Shimin - - 2013
Quantification of molecularly targeted radiotracer uptake in the myocardium from SPECT remains challenging in part due to potentially low levels of focal tracer uptake of presently available molecularly targeted agents and further degradation of cardiac SPECT by extracardiac radioactivity and partial-volume effect. The purpose of this study was to derive ...
Lee Mi-Young - - 2013
To evaluate the reproducibility of fetal left modified myocardial performance index (Mod-MPI) determined using a novel automated system. This was a prospective study of 116 exams from 110 normal singleton fetuses at 12.1 to 37.1 weeks of gestation. Two experienced operators each measured the left Mod-MPI twice manually and twice automatically ...
Chen Xiuyu X Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Electronic address: - - 2013
To investigate the relationship between T-wave inversions and left ventricular (LV) segmental hypertrophy and myocardial fibrosis assessed by cardiovascular magnetic resonance (CMR) in patients with non-apical hypertrophic cardiomyopathy (HCM). 196 consecutive patients with non-apical HCM underwent late gadolinium enhancement (LGE) CMR and 12-lead electrocardiogram. The distribution and magnitude of LV ...
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