Search Results
Results 201 - 250 of 785
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Liu Kan - - 2013
Coronary steal could develop in patients with chronic coronary artery disease (CAD) with collateral circulation, and adversely affect ventricular function and long-term clinical outcome. Poorly developed collaterals are more prone than well-developed collaterals to withdrawing their blood support to the collateralized myocardium due to higher collateral pathway resistance and lower ...
Hou Yang - - 2013
To evaluate the accuracy of low-dose coronary CTA with iterative reconstruction (IR) in the diagnosis of coronary artery disease (CAD) in patients with suspected CAD. Ninety-six patients with suspected CAD underwent low-dose prospective electrocardiogram-gated coronary CTA, with images reconstructed using IR. Image quality (IQ) of coronary segments were graded on ...
Russell Kristoffer - - 2013
Background: Left ventricular (LV) dyssynchrony reduces myocardial efficiency because work performed by one segment is wasted by stretching other segments. We introduce a novel non-invasive clinical method which quantifies wasted energy as the ratio between work consumed during segmental lengthening (wasted work) divided by work during segmental shortening. Methods: The ...
De Caterina Alberto R - - 2013
To angiographically assess myocardial perfusion in patients with Tako-Tsubo syndrome (TTS) in comparison with control individuals and patients with ST-elevation myocardial infarction (STEMI). Coronary microvascular dysfunction has been proposed as the pathophysiological mechanism underlying TTS. We retrospectively selected consecutive TTS patients showing typical left ventricular (LV) apical dysfunction admitted to ...
Kitada Ryoko - - 2013
The recently introduced pocket-sized portable transthoracic echocardiography (pTTE) is accurate for measurement of cardiac chamber size and function as well as for assessment of valvular regurgitation. This study aimed to compare the diagnostic accuracy of the pocket-sized pTTE with the standard TTE (sTTE) and assess its cost-effectiveness. The use of ...
Chow Kelvin - - 2013
To validate a new saturation recovery single-shot acquisition (SASHA) pulse sequence for T1 mapping and to compare SASHA T1 values in heart failure patients and healthy controls. The SASHA sequence consists of 10 electrocardiogram-triggered single-shot balanced steady-state free precession images in a breath-hold. The first image is acquired without magnetization ...
Gan Li-Ming - - 2013
Myocardial ischemia is recognized as an important mechanism increasing the risk for cardiovascular events in both symptomatic and asymptomatic patients. In addition to obstructive coronary diseases, systemic inflammation, macro- and microvascular function are additional important mechanisms contributing to the ischemic myocardium. Accumulating evidence indicates that coronary flow reserve (CFR) is ...
Uitterdijk Andre - - 2013
Objective To compare heart specific fatty acid binding protein (hFABP) and high sensitive troponin I (hsTnI) via serial measurements to identify early time points to accurately quantify infarct-size and no-reflow in a preclinical swine model of ST-elevated myocardial infarction (STEMI). Background Myocardial necrosis, usually confirmed by hsTnI or TnT, takes ...
Bratis K - - 2013
Recent studies have demonstrated that a detailed knowledge of the extent of angiographic coronary artery disease (CAD) is not a prerequisite for clinical decision making, and the clinical management of patients with CAD is more and more focused towards the identification of myocardial ischemia and the quantification of ischemic burden. ...
Vogel Britta - - 2013
Non-ischaemic heart failure is one of the today's most prevalent cardiovascular disorders. Since modern pharmacotherapy has proved to be very effective in delaying disease progression and preventing death, imaging modalities and molecular biomarkers play an important role in early identification and clinical management as well as risk assessment of patients. ...
Gibbs Bethany Barone - - 2013
Sedentary screen time (watching TV or using a computer) predicts cardiovascular outcomes independently from moderate and vigorous physical activity and could impact left ventricular structure and function through the adverse consequences of sedentary behavior. To determine whether sedentary screen time is associated with measures of left ventricular structure and function. ...
Palamalai Vikram - - 2013
This study evaluated the diagnostic performance of four point-of-care (POC) cardiac troponin I (cTnI) assays compared to a central laboratory cTnI assay for detecting myocardial injury and diagnosing acute myocardial infarction (AMI). Plasma obtained at admission, 3h, and 6h post-admission in 169 patients presenting with symptoms suggestive of acute coronary ...
Brinks Henriette - - 2013
OBJECTIVESPercutaneous closure of the transapical (TA) access site for large-calibre devices is an unsolved issue. We report the first experimental data on the TA PLUG device for true-percutaneous closure following large apical access for transcatheter aortic valve implantation.METHODSThe TA PLUG, a self-sealing full-core closure device, was implanted in an acute ...
Hasanien Amer A - - 2013
Sympathetic hyperactivity is linked with several adverse cardiovascular events in patients with acute coronary syndrome (ACS). Sympathetic activity increases early in the process of ischemia through 2 mechanisms. One originates from the central nervous system and leads to enhanced sympathetic activity. The other mechanism originates at the infarct zone and ...
Bettencourt Nuno N Departments of - - 2013
Cardiovascular magnetic resonance (CMR) myocardial perfusion imaging (MPI) is a state-of-the-art noninvasive modality for detection of myocardial ischemia and coronary artery disease. Magnetic resonance coronary angiography (MRCA) allows visualization of the coronary tree, but its incremental value as part of a CMR protocol including MPI and late gadolinium enhancement (LGE) ...
Jaarsma Caroline - - 2013
Although electrocardiography is frequently used as an initial test to detect or rule out previous myocardial infarction (MI), the diagnostic performance of commonly used electrocardiographic scoring systems is not well described. We aimed to determine the diagnostic accuracy of (1) the Universal Definition, (2) Minnesota ECG Code (MC), (3) Selvester ...
Farooq Vasim - - 2013
This study sought to validate the Logistic Clinical SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score in patients with non-ST-segment elevation acute coronary syndromes (ACS), in order to further legitimize its clinical application. The Logistic Clinical SYNTAX score allows for an individualized prediction of 1-year mortality ...
Oliveira Luciano Fonseca Lemos de - - 2013
Imaging techniques enable in vivo sequential assessment of the morphology and function of animal organs in experimental models. We developed a device for high-resolution single photon emission computed tomography (SPECT) imaging based on an adapted pinhole collimator. To determine the accuracy of this system for quantification of myocardial infarct area ...
Nough Hossein - - 2013
Patient assessment by imaging studies using contrast media is currently replacing open procedures, especially in high-risk patients. However, the use of such contrast media might result in acute events and injuries after the procedure. In the present study, we first determined the incidence of contrast-induced nephropathy (CIN) in a sample ...
Van Assche Lowie M R - - 2013
This article focuses on delayed contrast enhanced MRI (DE-MRI) to assess myocardial viability. We start by discussing previous literature that evaluated the potential importance of myocardial viability testing and follow up with the more recent Surgical Treatment for Heart Disease Trial (STICH) trial results. We then provide an overview of ...
Fan Cheng-Hsiang - - 2013
In this study, we propose to use morphological features that are easy to identify to differentiate myocardial ischemic beats from normal beats. In general, myocardial ischemia causes alterations in electrocardiographic (ECG) signal such as deviation in the ST segment. When the ST segment level deviates from a certain voltage, the ...
Panagiotou Christos - - 2013
This paper addresses the possibility of detecting presence of scar tissue in the myocardium through the investigation of vectorcardiogram (VCG) characteristics. Scarred myocardium is the result of myocardial infarction (MI) due to ischemia and creates a substrate for the manifestation of fatal arrhythmias. Our efforts are focused on the development ...
Mynard Jonathan P - - 2013
We validated a multi-scale model of a left-dominant coronary circulation using high fidelity pressure and flow data acquired in adult sheep and newborn lambs. The model incorporated a one-dimensional representation of the major left conduit coronary arteries, allowing for the study of wave propagation effects. The coronary microvasculature was represented ...
Maheshwari Sidharth - - 2013
Fragmented QRS (f-QRS) has been found to have higher sensitivity and/or specificity values for several diseases including remote and acute myocardial infarction, cardiac sarcoidosis etc, compared to other conventional bio-markers viz. Q-wave, ST-elevation etc. Several of these diseases do not have a reliable bio-marker and hence, patients suffering from them ...
de Chazal Philip - - 2013
Two simple algorithms for supraventricular (SVEB) and ventricular ectopic beat (VEB) detection using the electrocardiogram (ECG) are presented. Both algorithms use time-domain features and a linear classifier. The first algorithm requires QRS detection only and the second algorithm requires P, QRS and T wave segmentation. Data was obtained from the ...
Mao Song Shou - - 2013
The papillary and trabecular muscles constitute a significant percentage of left ventricular mass and volume. The influence of the papillary and trabecular muscles on left ventricular parameters has not been described with multidetector CT angiography. The aims of this study are (1) to derive reference values for left ventricular volumetric ...
Fischer Collin - - 2013
Numerous studies have compared coronary CT angiography (CTA) with quantitativecoronary angiography. However, the ability of coronary CTA to identify atherosclerosis and to accurately measure plaque and coronary area and volume measurements as compared with intravascular ultrasound (IVUS) has not been fully defined. We sought to assess the ability of coronary ...
Hamabe Lina - - 2013
The aim of the study was to assess the ability of two-dimensional tissue tracking (2DTT) to evaluate changes in left ventricular (LV) myocardial function associated with sustained high electrical pacing. Pacemakers were implanted at the right ventricular (RV) apex of five female Beagles, and sustained high electrical pacing of 250 ...
Yang Hyoung-Mo - - 2013
Objectives: The objective of this study was to assess the relationship between intravascular ultrasound (IVUS) parameters, including volumetric analysis, and fractional flow reserve (FFR). Background: Although it is known that coronary atherosclerosis burden measured by IVUS volumetric analysis is related with clinical outcomes, its relationship with functional significance remains unknown. ...
Kaudewitz D - - 2013
MicroRNAs are small non-coding RNAs that are detectable in plasma and serum. Circulating levels of microRNAs have been measured in various studies related to cardiovascular disease. Heparin is a potential confounder of microRNA measurements due to its known interference with polymerase chain reactions. In this study, platelet-poor plasma was obtained ...
Attanà Paola - - 2013
Objective: Assess if acid-base evaluation by Stewart's approach had a clinical role in cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI). There are three widely used approaches to investigate metabolic acidosis: base excess (BE), anion gap (AG) and the Stewart's approach or strong ion gap (SIG). Available studies suggest the ...
Schreck David M - - 2013
The cardiac dipolar field is represented by the measured 12-lead electrocardiogram (ECG) and 3-lead vectorcardiogram (VCG). The objective is to derive the 12-lead ECG and 3-lead VCG from 3 measured leads acquired from only 5 electrodes. This is a retrospective blinded study comparing measured and derived ECG and VCG tracings. ...
Yang Yuesong - - 2013
Myocardial infarct heterogeneity indices including peri-infarct gray zone are predictors for spontaneous ventricular arrhythmias events after ICD implantation in patients with ischemic heart disease. In this study we hypothesize that the extent of peri-infarct gray zone and papillary muscle infarct scores determined by a new multi-contrast late enhancement (MCLE) method ...
Monnet X - - 2013
/st>We tested the ability of mean acceleration (Acc) and peak velocity (Vpeak) of the aortic velocity signal measured by oesophageal Doppler to reflect left ventricular (LV) systolic performance. /st>We included critically ill patients in whom a fluid challenge (n=25) or the introduction of dobutamine, 5 µg kg(-1) min(-1) (n=25), was ...
Nadeau Colleen Austel - - 2013
Heart failure is increasing in incidence, prevalence, and mortality. The purpose of this study was to test the predictive accuracy of a screening tool to identify inpatients with heart failure. The tool demonstrated statistical significance for predictability, with 68.3% sensitivity, 86% specificity, and overall accuracy of 77.5%. The tool facilitated ...
Chen Yueh-Chung - - 2013
Diagnosis of coronary artery disease requires invasive procedures that are typically not implemented until clinical warning signs are apparent. The goal of this study was to determine the relation between the severity of coronary artery disease, as measured by the SYNTAX scoring system, with serum levels of fetuin-A and fibroblast growth ...
Rashidinejad H - - 2013
OBJECTIVE. Much attention has recently been focused on the underlying role of circulating inflammatory biomarkers such as high-sensitivity C-reactive protein for predicting cardiovascular disease progression. We therefore set out to assess the relationship between the value of high-sensitivity C-reactive protein and (i) coronary artery disease severity, and (ii) left ventricular ...
Chik William W B - - 2013
 BACKGROUND: Radiofrequency (RF) ablation causes thermal mediated irreversible myocardial necrosis. This study aimed to (i) characterize the thermal characteristics of RF ablation lesions with high spatial resolution using a thermochromic liquid crystal (TLC) myocardial phantom; and (ii) compare the thermochromic lesions with in vivo and in vitro ablation lesions. The ...
Obiagwu Chukwudi - - 2013
Left atrial (LA) abnormality, an easily quantifiable parameter of left ventricular (LV) diastolic dysfunction, has been associated with cardiovascular risk. Because during myocardial perfusion study (MPS), the abnormal LV activation pattern in patients with left bundle branch block (LBBB) frequently induces perfusion defects, a clinical correlate of early myocardial ischemia ...
Petersen John W - - 2013
BACKGROUND: Standard measures of left ventricular systolic and diastolic function often fail to identify left ventricular dysfunction in patients with heart failure and do not correlate with measures of functional capacity.Aim: To determine if speckle tracking echocardiography (STE)--determined measures of global and regional myocardial contractility have a linear association with ...
Prasad Aditya - - 2013
Objective: To compare the use of regadenoson to adenosine for measurement of fractional flow reserve (FFR). Background: FFR is an accepted method to assess the functional significance of intermediate coronary artery stenoses and uses adenosine to induce maximal hyperemia. The use of the selective A2a receptor agonist regadenoson for FFR ...
Chirife Raul - - 2013
BACKGROUND: Our objective was to evaluate the systolic index (SI), the ratio between rate-corrected left ventricular ejection time (LVETc), and a preejection period surrogate (PEPsu), to assess cardiac function in patients with DDD and cardiac resynchronization therapy (CRT) pacemakers. METHODS: LVETc and PEPsu were automatically measured from electrocardiogram and finger ...
Fortunato Orazio - - 2013
AIMS: Following an acute myocardial infarction (AMI), pro-angiogenic PCs are released from the bone marrow into the circulation and home to the ischemic site attracted by a chemokine gradient. It is unknown if components of this early homeostatic response might help forecast long-term clinical outcome. This study investigates if the ...
Senior Roxy - - 2013
OBJECTIVE: To compare sulphur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography (MCE) with single-photon-emission computed tomography (SPECT) relative to coronary angiography (CA) for assessment of coronary artery disease (CAD). BACKGROUND: Small-scale studies have shown that myocardial perfusion assessed by SonoVue-enhanced MCE is a viable alternative to SPECT for CAD assessment. However, ...
Naujorks Alexandre Antonio - - 2013
INTRODUCTION: Diastolic dysfunction may occur in fetuses with intrauterine growth restriction (IUGR) and may be assessed by myocardial tissue Doppler (MTD). We previously have shown that excursion index of the septum primum (EISP) is reduced in IUGR fetuses over 30 weeks because of a higher left atrial pressure. PATIENTS, SETTING, AND ...
Li Dong-Ye - - 2013
BACKGROUND: Real-time (RT) myocardial contrast echocardiography (MCE) is a novel method for the assessment of regional myocardial perfusion. We sought to evaluate the feasibility and diagnostic accuracy of quantitative RT-MCE in predicting significant coronary stenosis, with reference to quantitative coronary angiography. HYPOTHESIS: RT-MCE can identify anatomically significant coronary artery stenosis ...
Vietta Giovanna Grunewald - - 2013
AIMS: Evaluating myocardial infarct (MI) size prior to intervention is fundamental to ensure accurate results in experimental studies. However, this assessment is performed at late time points. We aimed to evaluate whether measuring plasma cardiac troponin I (cTnI) and performing echocardiographic assessment at earlier time points can predict the occurrence ...
Porto Italo - - 2013
Endothelial progenitor cells (EPCs) are released from the bone marrow during cardiac ischemic events, potentially influencing vascular and myocardial repair. We assessed the clinical and angiographic correlates of EPC mobilization at the time of primary percutaneous coronary intervention in 78 patients with ST elevation myocardial infarction and the impact of ...
Wu Alan H B - - 2013
BACKGROUND: Galectin-3 and soluble ST2 (sST2) are novel serum biomarkers of chronic heart failure. METHODS AND RESULTS: The biological variability of galectin-3 and sST2 was measured from a cohort of 17 healthy subjects where blood was taken once every 2 weeks for 8 weeks (n = 4 samples) and from ...
Osuga Tatsuyuki - - 2013
Objective-To evaluate left atrial phasic function in healthy dogs by means of 2-D speckle tracking echocardiography with time-left atrial area curve analysis and to assess repeatability and reproducibility of obtained measurements. Animals-6 healthy Beagles. Procedures-Each dog underwent echocardiography twice on different days (3 nonconsecutive examinations/d). Images were analyzed with offline ...
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