Search Results
Results 201 - 250 of 891
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Cullen Louise - - 2013
Risk stratification processes for patients with possible acute coronary syndrome (ACS) recommend the use of serial sensitive troponin testing over at least 6h. Troponin assays vary in their analytical performance. Utility in accurate risk stratification at 2h post-presentation is unknown. A diagnostic accuracy study of patients presenting to the emergency ...
McCabe James M - - 2013
For patients who undergo primary percutaneous coronary intervention (PCI) for ST-segment-elevation myocardial infarction, the door-to-balloon time is an important performance measure reported to the Centers for Medicare & Medicaid Services (CMS) and tied to hospital quality assessment and reimbursement. We sought to assess the use and impact of exclusion criteria ...
Opolski Maksymilian P - - 2013
The widespread clinical application of coronary computed tomography angiography (CCTA) has resulted in increased referral patterns of patients with intermediate coronary stenoses to invasive coronary angiography. We evaluated the application of advanced quantitative coronary angiography (A-QCA) for predicting fractional flow reserve (FFR) in intermediate coronary lesions detected on CCTA. Fifty-six ...
Abelin Anibal P - - 2013
Comparisons between dedicated risk scores in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) in real-world clinical practice are scarce. The aim of this study was to assess the diagnostic performance of the Global Registry of Acute Coronary Events (GRACE), Primary Angioplasty in Myocardial Infarction ...
Abidov Aiden - - 2013
Gated myocardial perfusion SPECT (GSPECT) is a major clinical tool, widely used for performing myocardial perfusion imaging procedures. In this review, we have presented the fundamentals of GSPECT and the ways in which the functional measurements it provides have contributed to the emergence of myocardial perfusion SPECT in its important ...
Li Shimin - - 2013
Quantification of molecularly targeted radiotracer uptake in the myocardium from SPECT remains challenging in part due to potentially low levels of focal tracer uptake of presently available molecularly targeted agents and further degradation of cardiac SPECT by extracardiac radioactivity and partial-volume effect. The purpose of this study was to derive ...
Lee Mi-Young - - 2013
To evaluate the reproducibility of fetal left modified myocardial performance index (Mod-MPI) determined using a novel automated system. This was a prospective study of 116 exams from 110 normal singleton fetuses at 12.1 to 37.1 weeks of gestation. Two experienced operators each measured the left Mod-MPI twice manually and twice automatically ...
Chen Xiuyu X Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Electronic address: - - 2013
To investigate the relationship between T-wave inversions and left ventricular (LV) segmental hypertrophy and myocardial fibrosis assessed by cardiovascular magnetic resonance (CMR) in patients with non-apical hypertrophic cardiomyopathy (HCM). 196 consecutive patients with non-apical HCM underwent late gadolinium enhancement (LGE) CMR and 12-lead electrocardiogram. The distribution and magnitude of LV ...
Deno Don Curtis - - 2013
Managing cardiac arrhythmias with catheter ablation requires positioning electrodes in contact with myocardial tissue. Objective measures to assess contact and effective coupling of ablation energy are sought. An electrical coupling index (ECI) was devised using complex impedance at 20 kHz to perform in the presence of ablation RF and deliver ...
Ryu Jaeil - - 2013
To assess the relationship between metabolic syndrome (MetS) and coronary atherosclerosis using coronary CT angiography (CCTA) as the evaluation tool in asymptomatic cardiovascular disease (CVD) free subjects. The presence and extent of coronary atherosclerosis in 755 asymptomatic self-referred subjects were measured using CCTA. The relationships between coronary atherosclerosis, MetS, and ...
Kang Soo-Jin - - 2013
The aim of this study was to assess the clinical and morphological predictors for functionally significant in-stent restenosis (ISR). Although they have been studied de novo in native coronary artery lesions, the relationships between clinical and morphological characteristics and the hemodynamic significance of ISR are not well understood. In 175 ...
Viviani Anselmi Chiara - - 2013
This study sought to assess the usefulness of clopidogrel-pathway genotyping and on-treatment platelet reactivity (OTR) testing in predicting major adverse cardiac events (MACE) in stable coronary artery disease (CAD) patients receiving drug-eluting stents (DES) under dual antiplatelet (clopidogrel plus aspirin) therapy. The role of pharmacogenetics and OTR in predicting MACE-death, ...
Smets P P Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, - - 2014
Boxer dogs are predisposed to congenital and adult onset cardiac diseases. Breed-specific reference values for M-mode and Doppler echocardiographic measurements previously have been established. Left ventricular (LV) end-systolic (ESV) and end-diastolic volumes (EDV) can be measured by M-mode or two-dimensional methods, such as Simpson's method of discs (SMOD). Reference ranges ...
Chiang Austin - - 2013
Great strides have been made in improving outcomes for patients with ST-elevation myocardial infarction (STEMI), predominately through initiatives focusing upon improving clinical processes "upstream" of percutaneous coronary intervention (PCI). The actual step-by-step mechanics of diagnostic angiography during STEMI and other aspects of the PCI procedure itself have received relatively little ...
Lairez Olivier - - 2013
The aim of this study was to assess the correlation between global wall thickening (GWT) obtained by gated-single photon emission computed tomography (SPECT) and echocardiographic measures [ejection fraction (EF), global longitudinal strain (GLS), and strain rate (GLSR)] and to compare their prognostic value for all-cause mortality. Seventy-four patients with referral ...
Peacock Andrew J - - 2013
-Most measures that predict survival in pulmonary hypertension (PH) relate directly to, or correlate with, right ventricular (RV) function. Direct assessment of RV function, using non-invasive techniques such as cardiac magnetic resonance imaging (CMRI), may therefore be an appropriate way of determining response to therapy and/or monitoring disease progression in ...
Schoene Peter - - 2013
Quantitative measures of the ventricular fibrillation waveform at the outset of resuscitation are associated with survival. However, little is known about the course of these measures during resuscitation and how this course is related to outcome. We evaluated 390 persons treated by emergency providers following out-of-hospital ventricular fibrillation arrest. We ...
Daskalov Ivaylo Rilkov - - 2013
The aim of the study was to investigate the relationship between the ejection fraction (EF) and the mitral annular systolic velocity (Sm) in patients with preserved left ventricular systolic function (EF>55%). The study task was to evaluate whether the assessment of Sm(avg) can be used as an alternative to the ...
Arisha Mohamed Moussa - - 2013
In the setting of primary prevention, most implantable cardiac defibrillators (ICD) are implanted more than 6 months after acute myocardial infarction (AMI). Abnormal heart rate turbulence (HRT) and T-wave alternans (TWA) are predictors of long-term sudden cardiac death (SCD). We intended to assess the predictive value of HRT and TWA ...
Bergerot Cyrille - - 2013
In the acute phase of myocardial infarction (MI), infarct size and microvascular obstruction (MVO) are important prognostic factors for cardiovascular outcome. MI size is a major determinant of myocardial function, but the specific effect of MVO is less documented. The aim of this study was to evaluate the impact of ...
Sá Luiz Antonio Batista de - - 2013
Right ventricular pacing may be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation triggering clinically relevant ventricular dysfunction is not fully established. To evaluate the clinical, echocardiographic findings of patients with previously normal left ventricular function underwent implantation of a ...
Kumagai Soichiro - - 2013
We sought to determine the morphologic predictors of major adverse cardiac events (MACEs) after successful percutaneous coronary intervention (PCI) with drug-eluting stents (DES), using integrated backscatter intravascular ultrasound (IB-IVUS). Conventional IVUS and IB-IVUS were performed in 260 consecutive patients who underwent PCI with DES. Three-dimensional analyses were performed to determine ...
Zhang Haosen - - 2013
To improve myocardial and blood T1 measurements with a multi-variable T1 fitting model specifically modified for a segmented multi-shot FLASH sequence. The proposed method was first evaluated in a series of phantoms simulating realistic tissues, and then in healthy rats (n = 8) and rats with acute myocardial infarction (MI) ...
Kraigher-Krainer Elisabeth - - 2013
To determine the frequency and magnitude of impaired systolic deformation in heart failure with preserved ejection fraction (HFpEF). While diastolic dysfunction is widely considered a key pathophysiologic mediator of HFpEF, the prevalence of concomitant systolic dysfunction has not been clearly defined. We assessed myocardial systolic and diastolic function in 219 ...
Dianati Maleki Neda - - 2013
We evaluated inter-reader agreement of the ST-segment between two electrocardiogram (ECG) core laboratories. Accurate measurement of the ST-segment is key to diagnosis and management of acute coronary syndromes (ACS). Clinical trials also rely on adherence to the pre-specified ECG eligibility criteria. 150 patients (100 ST-segment elevation (STE)-ACS, 50 non-STE-ACS) were ...
Thomas Gregory S - - 2013
Patients with LBBB or ventricular pacemaker undergoing MPI are at risk for false positive MPI results in the setting of an elevated heart rate (HR) with exercise or dobutamine stress. The areas of increased apparent ischemia are typically the LAD and septal territories. In a subanalysis of the ADVANCE MPI ...
Cuculi Florim - - 2013
Predicting the likely success of primary PCI to salvage potential infarcted myocardium is desirable. We compared early invasive parameters of coronary microcirculation function with the levels of circulating endothelin (ET-1) and 6-month ejection fraction after STEMI. Forty-four STEMI patients underwent assessment of coronary flow reserve (CFR) and index of myocardial ...
Vermes Emmanuelle - - 2013
Longitudinal shortening is traditionally considered the predominant part of global right ventricular (RV) systolic function. Less attention has been paid to transverse contraction. The aim of this study was to evaluate RV transverse motion by cardiovascular magnetic resonance (CMR) in a large cohort of patients and to assess its relationship ...
Pyxaras Stylianos A - - 2013
The purpose was to compare 3-dimensional quantitative coronary angiography (3D-QCA) with optical coherence tomography (OCT) for the functional assessment of nonobstructive coronary stenoses, as evaluated by fractional flow reserve (FFR). Fifty-five nonobstructive coronary stenoses (30%-50% diameter stenosis by visual estimation) were assessed in 36 patients using FFR, 2-dimensional QCA (2D-QCA), ...
Aldhilan Asim A Nuclear Medicine Section, Department of Medical Imaging, King Fahad Hospital, King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS) and King Abdullah International Medical Research Centre (KAIMRC), King Abdulaziz Medical City, - - 2014
A high transient ischemic dilatation ratio (TID) for the left ventricle (LV) from a gated myocardial perfusion imaging (G-MPI) study is widely believed to be associated with significant coronary artery disease (CAD). We have investigated the relationship between TID and CAD for our male Saudi Arabian patient population. In this ...
Shanks Miriam - - 2013
Fabry cardiomyopathy is characterized by progressive left ventricular hypertrophy (LVH) associated with diastolic dysfunction and is the most common cause of death in Fabry disease (FD). However, LVH is not present in all subjects, particularly early in disease progression and in female patients. Direct assessment of myocardial deformation by strain ...
Costa Salvatore P - - 2013
Global longitudinal strain (GLS) derived from two-dimensional speckle-tracking is an emerging technology, but lack of industry standards limits its application. Prior studies support using this tool to identify subclinical disease through serial changes, but the variability introduced by a change in vendor or reader is not well defined. Fifty study ...
Szadkowska Iwona - - 2013
Abstract Context: Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease. Objective: The study aimed to assess the relationship between galectin-3 levels and the occurrence of reinfarction early after myocardial infarction (MI). Methods: The study included 145 consecutive patients with first ...
Zheng Xiao-Zhi - - 2013
Abstract A new single-beat three-dimensional (3D) real time echocardiographic semi-automatic images processing (4D Auto LVQ) allows accurate assessment of left ventricular function, but whether it is suitable for the evaluation of right ventricular function remains unknown. To evaluate the feasibility of this procedure for assessing right ventricular volumes and function, ...
Coolen Bram F - - 2013
A high-quality, reproducible, multi-slice T2-mapping protocol for the mouse heart is presented. A T2-prepared sequence with composite 90° and 180° radiofrequency pulses in a segmented MLEV phase cycling scheme was developed. The T2-mapping protocol was optimized using simulations and evaluated with phantoms. Repeatability for determination of myocardial T2 values was ...
Sandau Kristin E - - 2013
To develop a conceptual definition of quality of life (QoL) with a left ventricular assist device (LVAD). Conceptual and operational definitions of QoL with an LVAD are lacking. A grounded theory method was used. Adult, outpatient LVAD recipients (n = 11) participated twice in individual or paired interviews. A conceptual definition of ...
Hatam Nahid - - 2013
Coronary angiography is the most accurate and standard method for investigating the anatomic status and blood supply to the heart tissue; however, this method has been overused during the past decade. The present study aimed to investigate the appropriateness of coronary angiography in the patients referred to the selected hospital ...
Ariza-Solé Albert - - 2013
The IFFANIAM study (Impact of frailty and functional status in elderly patients with ST segment elevation myocardial infarction undergoing primary angioplasty) is an observational multicenter registry to assess the impact of frailty and functional status on outcomes of elderly patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary angioplasty. STEMI ...
Hlatky Mark A - - 2013
Randomized trials have shown that fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) improves clinical outcome and reduces costs compared with visually guided PCI. FFR has been measured during invasive coronary angiography (ICA), but can now be derived noninvasively from coronary computed tomography (CT) angiography (cCTA) images (FFRCT ). ...
Epstein Stephen E - - 2013
One of the major dilemmas facing physicians is what diagnostic and therapeutic approaches should be recommended to those stable coronary artery disease patients whose symptoms are adequately controlled on medical therapy. This study sought to assess the evidence-based data relating to whether: 1) all patients with significant coronary lesions (i.e., ...
Zhou Wei W Department of Anesthesiology, University of California Los Angeles, - - 2013
Although rotational parameters by speckle tracking echocardiography (STE) have been previously compared to sonomicrometry and cardiac magnetic resonance imaging, few have examined the relationship between left ventricular (LV) rotational mechanics and intraventricular measures of load-independent contractility, LV stiffness, or ventriculoarterial coupling. The aim of this study was to compare the ...
Keshtkar Ahmad A Department of Medical Physics, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran ; Department of Biomedical Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, - - 2013
There are a variety of electrocardiogram based methods to detect myocardial infarction (MI) patients. This study used the signal averaged electrocardiogram (SAECG) and its wavelet coefficient as an index to detect MI. Orthogonal leads signals from 50 acute myocardial infarction (AMI) and 50 healthy subjects were selected from the national ...
Khosroshahi Ahmad Ghamei AG Department of Pediatrics, Urmia University of Medical Sciences, Urmia, - - 2013
Although there are several echocardiographic criteria, there is not yet a general consensus about the diagnosis of left ventricular noncompaction. The current criteria are mostly based on the areas with maximal noncompaction in the heart. The echocardiographer may miss this maximal point leading to a misdiagnosis. Accordingly, we suggested a ...
Hung Guang-Uei GU Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan 505, - - 2013
Over the past decades, stress/rest myocardial perfusion SPECT (MPS) has been utilized as a standard modality for the diagnosis, risk stratification and prognostic assessment of coronary artery disease (CAD). In addition to the perfusion information, MPS can also provide functional information of the left ventricle, including volume, ejection fraction, wall ...
Whitman Isaac - - 2013
We aimed to assess the diagnostic properties of ECG criteria for RVH measured by cardiac magnetic resonance imaging (cMRI) in adults without clinical cardiovascular disease. Current electrocardiographic (ECG) criteria for right ventricular hypertrophy (RVH) were based on cadaveric dissection in small studies. The Multi-Ethnic Study of Atherosclerosis performed cMRIs with ...
Fairbairn Timothy A - - 2013
Purpose:To determine if myocardial perfusion cardiac magnetic resonance (MR) imaging can show changes in myocardial blood flow (MBF) during the cold pressor test (CPT) and can allow identification of the differing endothelial function of smokers and nonsmokers when compared during adenosine stress.Materials and Methods:The study was approved by the institutional ...
Hsu Bailing B Nuclear Science and Engineering Institute, University of Missouri-Columbia, Columbia, MS 65211, - - 2013
Assessment of the relative distribution of myocardial flow with myocardial perfusion imaging (MPI) is methodologically limited to predict the presence or absence of flow-limited coronary artery disease (CAD). This limitation may often occur, when obstructive lesions involve multiple epicardial coronary arteries or disease-related disturbances of the coronary circulation coexist at ...
Vieira-Filho Normando G - - 2013
The left atrial volume index (LAVI) is a biomarker of diastolic dysfunction and a predictor of cardiovascular events. Three-dimensional echocardiography (3DE) is highly accurate for LAVI measurements but is not widely available. Furthermore, biplane two-dimensional echocardiography (B2DE) may occasionally not be feasible due to a suboptimal two-chamber apical view. Simplified ...
Tsang Wendy - - 2013
Three-dimensional echocardiographic (3DE) analysis provides better measurements of left ventricular (LV) volumes, ejection fraction, myocardial deformation, and dyssynchrony. Many studies have shown that this technique has high intrainstitutional reproducibility. However, interinstitutional reproducibility is low, limiting its adoption. The aim of this study was to determine if standardization of training could ...
Nijjer Sukhjinder S - - 2013
To determine whether the instantaneous wave-free ratio (iFR) can detect improvement in stenosis significance after percutaneous coronary intervention (PCI) and compare this with fractional flow reserve (FFR) and whole cycle Pd/Pa. A prospective observational study was undertaken in elective patients scheduled for PCI with FFR ≤0.80. Intracoronary pressures were measured ...
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