Search Results
Results 201 - 250 of 987
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Pinto Jostol J Resident, Department of Medicine, Father Muller Medical College , Mangalore, India - - 2014
Electrocardiogram (ECG) is a cost effective tool to evaluate left ventricular hypertrophy (LVH). However, its reliability is often questionable when compared to the gold standard - echocardiography.The validation of ECG as a tool to diagnose LVH would benefit centres that lack access to echocardiography. (1) To assess the efficacy of ...
Orlic Dejan D Clinical Center of Serbia, School of Medicine, Belgrade, - - 2014
Routine thrombus aspiration is proposed to be superior to conventional primary percutaneous coronary intervention (PCI) in terms of improved myocardial perfusion, in patients with ST-segment elevation acute myocardial infarction (STEMI). However, myocardial perfusion after thrombus aspiration has not been evaluated by a quantitative, invasive method. We intend to determine whether ...
Motwani Manish - - 2014
Two-dimensional (2D) perfusion cardiovascular magnetic resonance (CMR) remains limited by a lack of complete myocardial coverage. Three-dimensional (3D) perfusion CMR addresses this limitation and has recently been shown to be clinically feasible. However, the feasibility and potential clinical utility of quantitative 3D perfusion measurements, as already shown with 2D-perfusion CMR ...
Leung Melissa M Department of Cardiology, University of New South Wales, Liverpool Hospital, Liverpool, NSW, - - 2014
Aims: Coronary microvascular function has important diagnostic and prognostic implications but routine assessment is difficult. The index of microcirculatory resistance (IMR) is a reliable but invasive measure. We evaluated whether left ventricular contractile reserve (CR), measured with strain imaging on dobutamine echocardiography (DSE), is a reliable non-invasive measure of coronary ...
Karacavus Seyhan S Department of Nuclear Medicine, Faculty of Medicine, Bozok University, Yozgat, Turkey. - - 2014
Assessment of left ventricular (LV) function in patients with myocardial infarction (MI) provide useful diagnostic and prognostic information. Up to date, single photon emission tomography (SPET), positron emission tomography (PET), multidetector computed tomographic angiography, echocardiography (EC) and magnetic resonance imaging (MRI), have been used to examine LV parameters. However, due ...
Arrebola-Moreno A L AL Cardiology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain; Cardiovascular Sciences Research Centre, St George's University of London, London, United Kingdom. Electronic address: - - 2014
Whilst traditional studies have shown that obese individuals are at a higher risk of cardiovascular events compared to lean subjects, recent studies in patients with acute myocardial infarction (AMI) have suggested that obesity may exert protective effects (the "obesity paradox"). We sought to assess the relationship between body mass index ...
Sugamata Wataru W University of Yamanashi, Department of Internal Medicine II, Yamanashi, - - 2014
Measurement of either flow-mediated endothelium-dependent dilatation (FMD) of the brachial artery, brachial-ankle pulse wave velocity (baPWV), or intima-media thickness (IMT) of the carotid artery is useful for risk assessment of future cardiovascular events. This study examined whether combination of these vascular parameters may have an additive effect on the ability ...
Sakurai Daisuke D Division of Functional Diagnostics, Department of Health Sciences, Osaka University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, - - 2014
The assessment of post-systolic shortening (PSS) by speckle tracking echocardiography allows myocardial ischemic memory imaging. Because the endocardial layer is more vulnerable to ischemia, the assessment of this layer might be useful for detecting ischemic memory. Serial echocardiographic data were acquired from nine dogs with 2 min of coronary occlusion followed ...
Bhan Amit - - 2014
Objectives: To assess the feasibility and accuracy of high frequency speckle tracking echocardiography (STE) in a murine model of myocardial infarction (MI). Background: STE is used clinically to quantify global and regional cardiac function but its application in mice is challenging because of the small cardiac size and rapid heart ...
Wierzbowska-Drabik Karina K Chair and Department of Cardiology, Medical University of Lodz, Kniaziewicza 1/5, 91-347, Lodz, Poland, - - 2014
Speckle tracking echocardiography (STE) is a method of quantitative assessment of myocardial function complementary to ejection fraction and visual evaluation. Standard STE analysis, demands manual tracing of the myocardium whereas automated function imaging (AFI) offers more convenient (based on selection of three points) assessment of longitudinal strain. Nevertheless, feasibility and ...
Henninger Nils N From the Departments of Neurology (N.H., M.A.K., J.Z., M.M., R.P.G.) and Psychiatry (N.H.), University of Massachusetts Medical School, - - 2014
Leukoaraiosis (LA) predominantly affects the subcortical white matter, but mounting evidence suggests an association with cortical microvascular dysfunction and potentially decreased cortical ischemic tolerance. Thus, we sought to assess whether preexisting LA is predictive of the cortical infarct volume after middle cerebral artery branch occlusion and whether it relates to ...
Ladeiras-Lopes Ricardo R Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine of the University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal, - - 2014
Insulin resistance plays a central role in the pathophysiology of metabolic syndrome (MS). Its cardiac deleterious effects are characterized by an increase in fibrous tissue that increases myocardial stiffness and contributes to subclinical left ventricular diastolic dysfunction (LVDD) and heart failure with preserved ejection fraction in patients with MS. In ...
Menafoglio Andrea A Division of Cardiology, Ospedale San Giovanni Bellinzona, Bellinzona, - - 2014
The usefulness and modalities of cardiovascular screening in young athletes remain controversial, particularly concerning the role of 12-lead ECG. One of the reasons refers to the presumed false-positive ECGs requiring additional examinations and higher costs. Our study aimed to assess the total costs and yield of a preparticipation cardiovascular examination ...
Liu Chang C Departments of Cardiovascular Surgery (CL, LN, ZL, BW, GZ, LX, HL), Cardiology (CX, JS), and Computer Tomography (XX, KZ), The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, - - 2014
Although dobutamine stress myocardial contrast echocardiography (DSMCE) has been widely used for the prediction of myocardial functional recovery, dynamic changes that occur at the microcirculatory level during stress have been studied limitedly. The objective of the present study was to use low-dose DSMCE to assess microvascular damage and predict myocardial ...
Bamberg Fabian F Department of Clinical Radiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, Germany; Munich Heart Alliance, Munich, Germany. Electronic address: - - 2014
The aim of this study was to determine the feasibility of computed tomography (CT)-based dynamic myocardial perfusion imaging for the assessment of myocardial ischemia and infarction compared with cardiac magnetic resonance (CMR). Sequential myocardial CT perfusion imaging has emerged as a novel imaging technique for the assessment of myocardial hypoperfusion. ...
McKaigney Conor J CJ Department of Emergency Medicine, Queen's University, Ontario, Canada; Department of Emergency Medicine, Denver Health Medical Center, Denver, CO. Electronic address: - - 2014
Rapid assessment of left ventricular ejection fraction (LVEF) may be critical among emergency department (ED) patients. This study examined the predictive relationship between ED physician performed bedside mitral-valve E-point septal separation (EPSS) measurements to the quantitative, calculated LVEF. We further evaluated the relationship between ED physician visual estimates of global ...
Tilz Roland Richard RR Department of Cardiology, Asklepios Klinik St Georg, Lohmuehlenstr 5, 20099 Hamburg, - - 2014
Clinical outcomes following radiofrequency ablation of ventricular tachycardias (VTs) depend on catheter tip-to-tissue contact force (CF). Left-ventricular (LV) mapping is performed via antegrade-transseptal or retrograde-transaortic approaches, and the applied CF may depend on the approach used. This study evaluated (i) the impact of antegrade-transseptal vs. retrograde-transaortic LV-mapping approaches on CF ...
Esposito Michele M Molecular Cardiology Research Institute, Division of Cardiology, Tufts Medical Center, 800 Washington Street, Box #80, Boston, MA 02111 USA. - - 2014
The aim of this study was to assess myocardial blush (MB) using a novel software algorithm that quantifies time-density curves (TDC) after percutaneous coronary intervention (PCI). Thirty-two patients referred for elective PCI were enrolled. TDC curves were generated and mean maximal myocardial contrast density (Dmax) was calculated from 5 regions ...
Jellis Christine L CL School of Medicine, The University of Queensland, Brisbane, - - 2014
Subclinical diabetic cardiomyopathy (DCM) is frequent in asymptomatic subjects with type 2 diabetes (T2DM). We sought the response of functional and fibrosis markers to therapy in a trial of aldosterone antagonism for treatment of DCM. Biochemical, anthropometric, and echocardiographic data were measured in 225 subjects with T2DM. Myocardial function was ...
Parker Katherine M KM Department of Biomedical Engineering, University of Virginia, Charlottesville, - - 2014
The relationship between cardiac resynchronization therapy (CRT), left ventricular (LV) lead position, scar, and regional mechanical function influences CRT response. To determine LV lead position relative to LV structural characteristics in standard clinical practice, we developed and validated a practical yet mathematically rigorous method to register procedural fluoroscopic LV lead ...
Estep Jerry D JD Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas. Electronic address: - - 2014
Malfunction of a continuous-flow left ventricular assist device (CF-LVAD) due to device thrombosis is a potentially life-threatening event that currently presents a diagnostic challenge. We aimed to propose a practical echocardiographic assessment to diagnose LVAD malfunction secondary to pump thrombosis. Among 52 patients implanted with a CF-LVAD from a single ...
Gaggin Hanna K HK Division of Cardiology, Massachusetts General Hospital, Boston, - - 2014
This analysis aimed to perform a head-to-head comparison of 3 of the promising biomarkers of cardiovascular (CV) outcomes in heart failure (HF)-soluble ST2 (sST2), growth differentiation factor (GDF)-15, and highly-sensitive troponin T (hsTnT)-and to evaluate the role of serial measurement of these biomarkers in patients with chronic HF. sST2, GDF-15, ...
Perfetti Matteo M Institute of Cardiology, "G. d'Annunzio" University, Chieti, Pescara, - - 2014
Current cardiac magnetic resonance (CMR) quantitative signs for the diagnosis of myocarditis include myocardial edema, fibrosis and myocardial hyperemia (Hyp). Methods for the assessment of Hyp are actually complex and time-consuming. To test a simple and fast method to assess Hyp, using contrast enhancement steady state free precession (ceSSFP) technique. ...
Nørgaard Bjarne L BL Department of Cardiology, Aarhus University Hospital Skejby, Aarhus, Denmark. Electronic address: - - 2014
To determine the diagnostic performance of non-invasive FFR derived from standard acquired coronary computed tomography angiography (CTA) datasets (FFRCT) for the diagnosis of myocardial ischemia in patients with suspected stable coronary artery disease (CAD). Fractional flow reserve (FFR) measured during invasive coronary angiography (ICA) is the gold standard for lesion-specific ...
Lux Robert L RL Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of - - 2014
Precise measurement of the QT interval is often hampered by difficulty determining the end of the low amplitude T wave. Root mean square electrocardiography (RMS ECG) provides a novel alternative measure of ventricular repolarization. Experimental data have shown that the interval between the RMS ECG QRS and T wave peaks ...
Yildiz Abdulkadir - - 2014
The aim of the study was to evaluate the utility of the preprocedural platelet-lymphocyte ratio (PLR) for predicting no reflow in patients undergoing primary percutaneous intervention (PCI) for the treatment of ST-segment elevation myocardial infarction. The thrombolysis in myocardial infarction (TIMI) flow grades of 287 patients treated with primary PCI ...
Vardi Moshe - - 2014
Atherosclerosis and venous thromboembolism (VTE) share common risk factors. We set to assess the strength of the association between atherosclerosis risk factors and disease manifestation, and VTE, in patients with coronary artery disease undergoing percutaneous coronary intervention. We pooled data from 6 global randomized controlled trials assessing coronary stenting (ENDEAVOR ...
Yildirim Erkan - - 2014
Urocortin 1 (UCN1) has cardiostimulatory, vasodilator, diuretic and natriuretic effects and its expression increases in heart failure (HF). The aim of the study was to determine UCN1 levels in patients with HF, to evaluate UCN1's relationship with various clinical parameters and to assess UCN1 as a diagnostic marker in HF, ...
Joutsiniemi Esa E Heart Center, Turku University Hospital, Turku, - - 2014
We compared the accuracy of quantified myocardial flow reserve and absolute stress myocardial blood flow (MBF) alone in the detection of coronary artery disease (CAD). Myocardial flow reserve, i.e. ratio of stress and rest flow, has been commonly used to detect CAD with many imaging modalities. However, it is not ...
Hoey E T D ET Department of Radiology, Heart of England NHS Foundation Trust, Birmingham, West Midlands, UK. Electronic address: - - 2014
Hypertrophic cardiomyopathy (HCM) is the most common inheritable cardiovascular disorder. Although many HCM patients remain asymptomatic, sudden death (SD) can occur as the initial manifestation of the disease. It has been hypothesized that myocardial architectural disorganization and scarring represent an unstable electrophysiological substrate that creates susceptibility to malignant ventricular arrhythmias. ...
Ebrille Elisa E Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, - - 2014
Outflow tract ventricular arrhythmia (OTVA) can be complicated to target for ablation when originating from either the periaortic or pulmonary valve (PV) region. Both sites may present with a small R wave in lead V1. However, the utility of lead I in distinguishing these arrhythmia locations is unknown. Thirty-six consecutive ...
Xu Luhong L Institute of Cardiovascular Disease Research, Xuzhou Medical College, 84 West Huaihai Road, Xuzhou, Jiangsu 221002, - - 2014
The association between the levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and the severity of coronary artery disease (CAD) diagnosed by coronary angiography and other approaches has been investigated. The clinical application of NT-proBNP is restricted by the drawbacks of these techniques now available in screening out patients who need ...
Fernando Pasan P Nordion, 447 March Road, Ottawa, ON, K2K 1X8, Canada, - - 2014
Myocardial perfusion scintigraphy is a valuable clinical tool for assessing coronary blood flow deficits in patients. We recently synthesized a new iodinated compound ((123)I-CMICE-013) based on rotenone and showed that it has excellent performance as a radiotracer for myocardial perfusion imaging. Here, we describe the cellular toxicity and subacute toxicity ...
Dweck Marc Richard MR British Heart Foundation/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, - - 2014
The assessment of myocardial ischemia represents a cornerstone in our approach to coronary artery disease. Indeed many of the clinical decisions we make revolve around the results of stress testing, the assessment of coronary luminal stenoses and, more recently, fractional flow reserve measurements. Whilst the assessment of ischemia is often ...
Iskandrian Ami E AE Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: - - 2014
Myocardial perfusion imaging (MPI) with gated single-photon emission tomography provides important information on the extent and severity of myocardial perfusion abnormalities, including myocardial ischemia. The availability of software for automated quantitative assessment of myocardial perfusion in an objective and more reproducible manner than visual assessment has allowed MPI to be ...
Mordini Federico E FE Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland; Department of Cardiology, Veterans Affairs Medical Center, Washington, - - 2014
This study's primary objective was to determine the sensitivity, specificity, and accuracy of fully quantitative stress perfusion cardiac magnetic resonance (CMR) versus a reference standard of quantitative coronary angiography. We hypothesized that fully quantitative analysis of stress perfusion CMR would have high diagnostic accuracy for identifying significant coronary artery stenosis ...
Shuster Jerrica E JE PGY2 Pharmacy Resident, Cardiology Specialty, Clinical - - 2014
Clinical surveillance systems (CSS) are utilized by many health care institutions to help identify at-risk patients, prioritize care, improve the clinical services provided, and increase compliance with the Center for Medicare and Medicaid Services (CMS) core measures. This study will assess the accuracy and practicality of a CMS acute myocardial ...
De Smedt Delphine D Department of Public Health, Ghent University, Belgium. Electronic address: - - 2014
The aim of this study was to compare EuroQol five-dimensional (EQ-5D) utility scores and six-dimensional health state classification (SF-6D) utility scores (derived from the 12-Item Short-Form Health Survey [SF-12]) by using a large European sample of patients with stable coronary heart disease. Special attention was given to country-specific results. Data ...
Bière Loïc L L'UNAM Université, Angers, France ; Université Angers, UPRES EA3860, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU Angers, Service de Cardiologie, Angers, - - 2014
We assessed the value of speckle tracking imaging performed early after a first ST-segment elevation myocardial infarction (STEMI) in order to predict infarct size and functional recovery at 3-month follow-up. 44 patients with STEMI who underwent revascularization within 12 h of symptom onset were prospectively enrolled. Echocardiography was performed 3.9±1.2 ...
Rakowski Tomasz T Second Department of Cardiology, Jagiellonian University Medical College, Krakow, - - 2014
There are still only limited data concerning the use of creatine kinase-MB (CKMB) values for predicting infarct size in long-term follow up in patients with ST-segment elevation myocardial infarction (STEMI) who have undergone primary percutaneous coronary intervention (PCI). The aim of this study was to analyze the correlation between CKMB ...
Schoenenberger A A Division of Geriatrics, Department of General Internal Medicine, Inselspital, Bern, SWITZERLAND; - - 2014
Prediction of arrhythmic events (AEs) has gained importance with the availability of implantable cardioverter-defibrillators (ICDs), but is still imprecise. This study evaluated the innovative Wedensky modulation index (WMI) as predictor of AEs. In this prospective cohort, 179 patients with coronary artery disease (CAD) referred for AE risk assessment underwent baseline ...
Bekler Adem A Department of Cardiology, Canakkale Onsekiz Mart University, School of Medicine, Canakkale, - - 2014
Background Red cell distribution width (RDW) and fragmented QRS (fQRS) complexes have also been reported to be pre-dictors of cardiac events and all-cause mortality in coronary artery disease (CAD). We aimed to investigate the association of serum red cell distribution width (RDW) levels and fQRS in patients with non-ST elevated ...
Naar Jan - - 2014
Study objective: To compare parameters of diastolic function as assessed by radionuclide ventriculography (RNVG) and Doppler echocardiography (ECHO) in the patients with chronic heart failure and reduced ejection fraction (HF REF). Patients and methods: RNVG and ECHO were performed on the same day in 40 patients with systolic chronic HF, ...
Shen B X BX Department of Radiology, Affiliated Nanshan Hospital of Guangdong Medical College, Shenzhen, Guangdong, China - - 2014
We aimed to assess parameters reflecting left ventricular function by dual-source computed tomography (DSCT) with echocardiography (ECG) as control. Fifty-eight patients with coronary heart disease (CHD) were recruited from January to June 2011; 29 CHD patients had type II diabetes. All patients were assessed by cardiac DSCT and ECG examination. ...
Stähli Barbara Elisabeth BE Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Zurich, - - 2014
In patients with suspected acute coronary syndrome (ACS), rapid triage is essential. The aim of this study was to establish a tool for risk prediction of 30-day cardiac events (CE) on admission. 30-day cardiac events (CE) were defined as early coronary revascularization, subsequent myocardial infarction, or cardiovascular death within 30 ...
Qu Xinkai X Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, - - 2014
Accurate assessment of coronary chronic total occlusion (CTO) lesion is essential to design an appropriate procedural strategy before revascularization. The present study aims to evaluate the significance of a single multislice computed tomography (MSCT) examination in patients with CTO lesion. We retrospectively analyzed the clinical data of 23 CTO lesions ...
Jiang Zhibin Z Department of Cardiothoracic Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, P.R. - - 2014
Postoperative myocardial infarction (PMI) is one of the most serious complications of cardiac surgeries. No preoperative biomarker is currently available for predicting PMI after cardiac surgeries. In the present study, we used a phage display peptide library to screen potential preoperative peptide biomarkers for predicting PMI after coronary artery bypass ...
Kaplan Sahin S Faculty of Medicine, Karadeniz Technical University Trabzon, - - 2014
Epicardial adipose tissue (EAT) is a tissue around the heart with visceral adipose properties. It can affect the structure and functions of the myocardium and coronary arteries through inflammatory markers and regulators. The myocardial performance (Tei) index is a parameter capable of globally assessing systolic and diastolic heart functions. This ...
Tsai Jang-Zern JZ Department of Electrical Engineering, National Central University, Jhongli City, Taoyuan County, - - 2014
White matter hyperintensities (WMHs) of presumed vascular origin are common in ageing population, especially in patients with acute cerebral infarction and the volume has been reported to be associated with mental impairment and the risk of hemorrhage from antithrombotic agents. WMHs delineation can be computerized to minimize human bias. However, ...
Stevanovic Ana A Department of Anaesthesiology, University Hospital of the RWTH Aachen, Aachen, - - 2014
Cardiac surgery is accompanied by an increase of oxidative stress, a significantly reduced antioxidant (AOX) capacity, postoperative inflammation, all of which may promote the development of organ dysfunction and an increase in mortality. Selenium is an essential co-factor of various antioxidant enzymes. We hypothesized a less pronounced decrease of circulating ...
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