Search Results
Results 201 - 250 of 928
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Chow Benjamin Jw - - 2013
The prevalence of heart failure (HF) is rising in industrialized and developing countries. Though invasive coronary angiography (ICA) remains the gold standard for anatomical assessment of coronary artery disease in HF patients, alternatives are being sought. Computed tomographic coronary angiography (CTA) has emerged as an accurate non-invasive diagnostic tool for ...
Schmidt Renate R Adult Congenital and Valvular Heart Disease Center, Department of Cardiology and Angiology, University Hospital of Münster, Münster, - - 2013
Patients are commonly affected by ventricular dysfunction and heart failure after Fontan palliation. Reliable quantification of ventricular function is of interest but hampered by complex ventricular anatomy and physiology. We aimed to assess myocardial function using a novel cardiac magnetic resonance imaging (CMR)-based feature-tracking (FT) technique and to study its ...
Sakamoto Fumi F Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Kumamoto, 860-0821, Japan, - - 2013
We assessed the value of combining (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy for the discrimination of dementia with Lewy bodies (DLB) from other types of dementia. We subjected 252 consecutive patients with clinically suspected DLB to both (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy. Patients with Parkinson's ...
Zafar Haroon H Tissue Optics & Microcirculation Imaging Facility, National University of Ireland, Galway, Ireland; National Biophotonics & Imaging Platform, Dublin, Ireland. Electronic address: - - 2013
The main objective of this study is to determine the correlation between fractional flow reserve (FFR)- and frequency domain optical coherence tomography (FD-OCT)-measured lumen parameters, and to determine the diagnostic competence of FD-OCT concerning the identification of severe coronary stenosis. A total of 41 coronary stenoses in 30 patients were ...
Wildgruber Moritz M 1Department of Diagnostic and Interventional Radiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; International Graduate School of Science and Engineering, Technische Universität München, Garching, - - 2013
-To prospectively evaluate an elastin-specific magnetic resonance contrast agent (ESMA) for in-vivo targeting of elastic fibers in myocardial infarction and post-infarction scar remodeling. -Myocardial infarction (MI) was induced in C57BL/6J mice (n=40) by permanent ligation of the left anterior descending coronary artery (LAD). Magnetic Resonance Imaging (MRI) was performed at ...
Mueller Christian C Department of Cardiology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, - - 2013
Biomarkers complement clinical assessment and the 12-lead ECG in the diagnosis, risk stratification, triage, and management of patients with suspected acute coronary syndrome (ACS). While there is broad consensus that cardiac troponin (cTn) I or T is the preferred biomarker in clinical practice, important uncertainties remain regarding the value of ...
Gimelli Alessia A Fondazione Toscana Gabriele Monasterio, Via Moruzzi, 1, 56124 Pisa, - - 2013
To investigate the relationships between regional adrenergic innervation heterogeneity, myocardial perfusion, and contractile function obtained by means of a low-dose imaging protocol with a cadmium-zinc-telluride (CZT) dedicated camera. Twenty-eight patients with or without ischaemic heart disease underwent (123)I-metaiodobenzylguanidine (MIBG) planar scintigraphic and CZT early and delayed evaluations followed by (99m)Tc-tetrofosmin ...
Frederiksen Christian Alcaraz - - 2013
The aim of the study was to compare the diagnostic accuracy of point-of-care cardiac ultrasonography performed by a novice examiner against results from a specialist in cardiology with expert skills in echocardiography, with regard to the assessment of six clinically relevant cardiac conditions in a population of ward patients from ...
Miller Christopher A CA North West Heart Centre and The Transplant Centre, University Hospital of South Manchester, Wythenshawe Hospital, Manchester, UK; Centre for Imaging Sciences & Biomedical Imaging Institute, University of Manchester, UK; Institute of Cardiovascular Sciences, University of Manchester, UK. Electronic address: - - 2013
To evaluate the diagnostic performance of multiparametric cardiovascular magnetic resonance (CMR) for detecting cardiac allograft vasculopathy (CAV) using contemporary invasive epicardial artery and microvascular assessment techniques as reference standards, and to compare the performance of CMR with that of angiography. CAV continues to limit the long-term survival of heart transplant ...
Mouden Mohamed - - 2013
Coronary artery calcium (CAC) scores influence the pre-test likelihood of ischemia in patients undergoing myocardial perfusion imaging (MPI). We investigated the influence of CAC score knowledge on the visual interpretation of MPI in patients referred for the diagnostic work-up of suspected coronary artery disease. We retrospectively analyzed symptomatic patients who ...
Bohyn Emilie E Medical Emergency Service of Annecy, Annecy Health Center, Pringy, France. Electronic address: - - 2013
High-sensitivity troponin (HS-TnT) combined with copeptin have been proposed to expedite the diagnostic exclusion of acute myocardial infarction. The Global Registry of Acute Coronary Events (GRACE) has been validated and recommended by the European Society of Cardiology as a prognostic score in the management of acute coronary syndrome (ACS) without ...
Motiwala Shweta R - - 2013
Myocardial remodeling is pivotal in the progression and complication of chronic heart failure (HF). We assessed serial measurement of five biomarkers with biologic links to remodeling (biglycan, secreted frizzled-related protein 3, endostatin, insulin-like growth factor binding protein 7 [IGFBP7], mimecan) in 142 patients with HF followed through 882 office visits. ...
van Slochteren Frebus J - - 2013
Local layer-specific myocardial deformation after myocardial infarction (MI) has not been studied extensively although the sub-endocardium is more vulnerable to ischemia and interstitial fibrosis deposition. Radiofrequency (RF) ultrasound-based analysis could provide superior layer-specific radial strain estimation compared with clinically available deformation imaging techniques. In this study, we used RF-based myocardial ...
Kim Kyung-Hee KH Department of Medicine, Seoul National University Hospital, Seoul, Republic of - - 2013
This study sought to determine whether computational modeling can be used to predict the functional outcome of coronary stenting by virtual stenting of ischemia-causing stenoses identified on the pre-treatment model. Computed tomography (CT)-derived fractional flow reserve (FFR) is a novel noninvasive technology that can provide computed (FFRct) using standard coronary ...
Snoer Martin - - 2013
Despite revascularization and optimal medical treatment, patients with coronary artery disease (CAD) have reduced exercise capacity. In the absence of coronary artery stenosis, coronary flow reserve (CFR) is a measure of coronary microvascular function, and a marker of future poor outcome in CAD patients. The aim of this study was ...
Mazurek Tomasz - - 2013
Extravascular expression of inflammatory mediators may adversely influence coronary lesion formation and plaque stability through outside-to-inside signaling. It has been also shown, that maximal standardized uptake value (SUV) of 18-fluorodeoxyglucose (FDG) detected by positron emission tomography (PET/CT) is proportional to macrophage density. To investigate, whether inflammatory activity of pericoronary adipose ...
Christenson Eric - - 2013
Cardiac troponin I (cTnI) and T (cTnT) have displaced myoglobin and creatine kinase-MB as the preferred markers of myocardial injury and have become the cornerstones for diagnosis of myocardial infarction (MI). Current guidelines for MI diagnosis give specific recommendations for cTnI and cTnT assays including instructions to reliably measure values ...
Weinsaft Jonathan W - - 2013
Left ventricular (LV) infarct size is a prognostic determinant after acute myocardial infarction (AMI). ECG data have been used to measure infarct size, but conventional approaches use multiparametric algorithms that have limited clinical applicability. This study tested a novel ECG approach - based solely on Q wave area - for ...
Pirhan O - - 2013
Aim: Myocardial performance index (MPI) is a well known prognostic parameter in acute myocardial infarction (AMI) patients, which has been used to assess global cardiac functions. In this study, we aimed to evaluate the corelation between the MPI levels obtained by PW doppler and Tissue doppler ultrasonography with reperfusion in ...
Doyle Mark M Allegheny General Hospital, Pittsburgh, PA, - - 2013
To introduce an algorithmic approach to improve the interpretation of myocardial perfusion images in women with suspected myocardial ischemia. Gated single photon emission computed tomography (SPECT) and magnetic resonance (MR) myocardial perfusion imaging (MPI) approaches have relatively poor diagnostic and prognostic value in women with suspected myocardial ischemia. Here we ...
Peer Maya M Department of Internal Medicine, Woltson Medical Center, Holon, - - 2013
Left ventricular hypertrophy (LVH) is recognized as an independent predictor of cardiovascular morbidity and mortality in hypertensive patients. Thus, it is critical to understand the mechanisms underlying the development of LVH for formulation screening and treatment strategies. This study was designed to determine the association between echographically determined LVH measures ...
Harms Craig A CA North Carolina State University, College of Veterinary Medicine, Center for Marine Sciences and Technology, Morehead City, NC 28557, USA. - - 2013
Electrocardiography (ECG) was performed on captured free-ranging bottlenose dolphins (Tursiops truncatus) during a health assessment exercise and compared with that of a Navy collection of dolphins habituated to handling out of water in order to assess possible cardiovascular impacts of capture and handling. Six-lead recordings (I, II, III, aVr, aVl, ...
Anwar Ashraf M AM Department of Cardiology, King Fahd Armed Forces Hospital, Jeddah, Saudi-Arabia. ; Department of Cardiology, Al-Azhar University, Cairo, - - 2013
Visual assessment of wall motion abnormalities (WMA) by 2-dimensional echocardiography (2DE) is the most semi-quantitative method used to detect coronary artery disease (CAD), but it carries many limitations. Speckle tracking echocardiography (STE) overcomes these limitations and allows an objective quantification of myocardial deformation. The aim of the study to examine ...
Rossi Alexia - - 2013
-Coronary lesions with a diameter narrowing ≥ 50% on visual CT coronary angiography (CTCA) are generally considered for referral to invasive coronary angiography (ICA). However, similarly to ICA, visual CTCA is often inaccurate in detecting functionally significant coronary lesions. We sought to compare the diagnostic performance of quantitative CTCA with ...
van Rosendael Philippe J - - 2013
Aims: To assess the left atrial appendage (LAA) geometry with multidetector-row computed tomography (MDCT) and its implications for selection of closure devices. Methods and results: One hundred and ninety-seven patients who underwent MDCT prior to catheter ablation for atrial fibrillation were evaluated. Feasibility for Watchman and Amplatzer Cardiac Plug (ACP) ...
Sharma Abhishek A Department of Medicine, Maimonides Medical Center, Brooklyn, New York. Electronic address: - - 2013
We compare the diagnostic accuracy of multidetector row computed tomography (MDCT) to cardiac magnetic resonance imaging (CMR) for evaluating global left ventricular function. We systematically searched PubMed, CINAHL, Cochrane CENTRAL, Scopus, and the Web of Science databases for studies published between 1966 to January 2013 that compared left ventricle (LV) ...
Chin Calvin W L - - 2013
To determine the optimal T1 mapping approach to assess myocardial fibrosis at 3T. T1 mapping was performed at 3T using the modified look-locker-inversion sequence in 20 healthy volunteers and 20 patients with aortic stenosis (AS). Pre- and post-contrast myocardial T1, the partition coefficient (λ; ΔRmyocardium/ΔRblood, where ΔR = 1/post-contrast T1 ...
Jacquier Alexis A Department of Radiology, Aix Marseille Université, Hôpital Universitaire la Timone, Marseille, France; Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR CNRS n° 6612, Aix Marseille Université, Faculté de Médecine de Marseille, Marseille, - - 2013
1) To assess the myocardial partition coefficient (λ) of gadolinium quantified using T1 mapping in dilated cardiomyopathy (DCM); and 2) to assess the impact of increased λ on left ventricular (LV) circumferential strain and ejection fraction in DCM. Seventeen patients with DCM and 11 controls were prospectively included. All patients ...
Biere Loïc L L'UNAM Université, Angers, France; Université d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. Electronic address: - - 2013
To describe the time course of myocardial scarring after transapical-transcatheter aortic valve implantation (TA-TAVI) with the Edwards SAPIEN XT™ and the Edwards SAPIEN™ prosthesis in a 3-month follow-up study using cardiac magnetic resonance imaging (CMR). In 20 TA-TAVI patients, CMR was performed at discharge and 3 months (3M). Cine-MRI was ...
Bauer M - - 2013
Synthetic patch materials currently in use have major limitations, such as high susceptibility to infections and lack of contractility. Biological grafts are a novel approach to overcome these limitations, but do not always offer sufficient mechanical durability in early stages after implantation. Therefore, a stabilising structure based on resorbable magnesium ...
Sundh Frida F Department of Clinical Physiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Duke Clinical Research Institute, Durham, North Carolina, - - 2013
Electrocardiographic (ECG) Selvester QRS score criteria with false indication of anteroseptal scarring consistent with myocardial infarction have been found in patients with ostium secundum atrial septal defect (OS-ASD). The objective of this study was to evaluate ECGs pre and post percutaneous transcatheter OS-ASD closure to test the hypothesis that the ...
Kurisu Satoshi - - 2013
Recent studies have shown good correlations between echocardiography and Tl-201 gated single-photon emission computed tomography (SPECT) for the assessment of left ventricular volumes and ejection fraction. We assessed how left ventricular geometry affected correlations between these values measured by the 2 methods in patients with known or suspected coronary artery ...
Agostinelli Angela - - 2013
T-wave offset (Toff) identification may be jeopardized by the presence of a significant inter-method (IMV) and inter-lead (ILV) Toff variability. Thus, the aim of the present study was to investigate if the dominant T wave (DTW) may be used to enhance Toff-identification reliability. DTWs and 15-lead ECG T waves of ...
Rochitte Carlos E - - 2013
To evaluate the diagnostic power of integrating the results of computed tomography angiography (CTA) and CT myocardial perfusion (CTP) to identify coronary artery disease (CAD) defined as a flow limiting coronary artery stenosis causing a perfusion defect by single photon emission computed tomography (SPECT). We conducted a multicentre study to ...
Parlak Ismail Burak - - 2013
The existence of a right-to-left shunt may increase the likelihood of micro-embolism by allowing a flux of bubbles under hyperbaric conditions. The aim of the study was to measure the relationship between these shunts and bubbles in 10 consecutive subjects using trans-thoracic and trans-esophageal echocardiography. In video frames, all cardiac ...
Cullen Louise - - 2013
Risk stratification processes for patients with possible acute coronary syndrome (ACS) recommend the use of serial sensitive troponin testing over at least 6h. Troponin assays vary in their analytical performance. Utility in accurate risk stratification at 2h post-presentation is unknown. A diagnostic accuracy study of patients presenting to the emergency ...
McCabe James M - - 2013
For patients who undergo primary percutaneous coronary intervention (PCI) for ST-segment-elevation myocardial infarction, the door-to-balloon time is an important performance measure reported to the Centers for Medicare & Medicaid Services (CMS) and tied to hospital quality assessment and reimbursement. We sought to assess the use and impact of exclusion criteria ...
Opolski Maksymilian P - - 2013
The widespread clinical application of coronary computed tomography angiography (CCTA) has resulted in increased referral patterns of patients with intermediate coronary stenoses to invasive coronary angiography. We evaluated the application of advanced quantitative coronary angiography (A-QCA) for predicting fractional flow reserve (FFR) in intermediate coronary lesions detected on CCTA. Fifty-six ...
Abelin Anibal P - - 2013
Comparisons between dedicated risk scores in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) in real-world clinical practice are scarce. The aim of this study was to assess the diagnostic performance of the Global Registry of Acute Coronary Events (GRACE), Primary Angioplasty in Myocardial Infarction ...
Abidov Aiden - - 2013
Gated myocardial perfusion SPECT (GSPECT) is a major clinical tool, widely used for performing myocardial perfusion imaging procedures. In this review, we have presented the fundamentals of GSPECT and the ways in which the functional measurements it provides have contributed to the emergence of myocardial perfusion SPECT in its important ...
Li Shimin - - 2013
Quantification of molecularly targeted radiotracer uptake in the myocardium from SPECT remains challenging in part due to potentially low levels of focal tracer uptake of presently available molecularly targeted agents and further degradation of cardiac SPECT by extracardiac radioactivity and partial-volume effect. The purpose of this study was to derive ...
Lee Mi-Young - - 2013
To evaluate the reproducibility of fetal left modified myocardial performance index (Mod-MPI) determined using a novel automated system. This was a prospective study of 116 exams from 110 normal singleton fetuses at 12.1 to 37.1 weeks of gestation. Two experienced operators each measured the left Mod-MPI twice manually and twice automatically ...
Chen Xiuyu X Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Electronic address: - - 2013
To investigate the relationship between T-wave inversions and left ventricular (LV) segmental hypertrophy and myocardial fibrosis assessed by cardiovascular magnetic resonance (CMR) in patients with non-apical hypertrophic cardiomyopathy (HCM). 196 consecutive patients with non-apical HCM underwent late gadolinium enhancement (LGE) CMR and 12-lead electrocardiogram. The distribution and magnitude of LV ...
Deno Don Curtis - - 2013
Managing cardiac arrhythmias with catheter ablation requires positioning electrodes in contact with myocardial tissue. Objective measures to assess contact and effective coupling of ablation energy are sought. An electrical coupling index (ECI) was devised using complex impedance at 20 kHz to perform in the presence of ablation RF and deliver ...
Ryu Jaeil - - 2013
To assess the relationship between metabolic syndrome (MetS) and coronary atherosclerosis using coronary CT angiography (CCTA) as the evaluation tool in asymptomatic cardiovascular disease (CVD) free subjects. The presence and extent of coronary atherosclerosis in 755 asymptomatic self-referred subjects were measured using CCTA. The relationships between coronary atherosclerosis, MetS, and ...
Kang Soo-Jin - - 2013
The aim of this study was to assess the clinical and morphological predictors for functionally significant in-stent restenosis (ISR). Although they have been studied de novo in native coronary artery lesions, the relationships between clinical and morphological characteristics and the hemodynamic significance of ISR are not well understood. In 175 ...
Smets P P Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, - - 2014
Boxer dogs are predisposed to congenital and adult onset cardiac diseases. Breed-specific reference values for M-mode and Doppler echocardiographic measurements previously have been established. Left ventricular (LV) end-systolic (ESV) and end-diastolic volumes (EDV) can be measured by M-mode or two-dimensional methods, such as Simpson's method of discs (SMOD). Reference ranges ...
Viviani Anselmi Chiara C Istituto di Ricovero e Cura a Carattere Scientifico Multimedica, Milan, - - 2013
This study sought to assess the usefulness of clopidogrel-pathway genotyping and on-treatment platelet reactivity (OTR) testing in predicting major adverse cardiac events (MACE) in stable coronary artery disease (CAD) patients receiving drug-eluting stents (DES) under dual antiplatelet (clopidogrel plus aspirin) therapy. The role of pharmacogenetics and OTR in predicting MACE-death, ...
Chiang Austin - - 2013
Great strides have been made in improving outcomes for patients with ST-elevation myocardial infarction (STEMI), predominately through initiatives focusing upon improving clinical processes "upstream" of percutaneous coronary intervention (PCI). The actual step-by-step mechanics of diagnostic angiography during STEMI and other aspects of the PCI procedure itself have received relatively little ...
Lairez Olivier - - 2013
The aim of this study was to assess the correlation between global wall thickening (GWT) obtained by gated-single photon emission computed tomography (SPECT) and echocardiographic measures [ejection fraction (EF), global longitudinal strain (GLS), and strain rate (GLSR)] and to compare their prognostic value for all-cause mortality. Seventy-four patients with referral ...
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