Search Results
Results 301 - 350 of 1492
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Yary Teymoor - - 2010
Despite significant improvements in the treatment of coronary heart disease (CHD), it is still a major cause of mortality and morbidity among the Iranian population. Epidemiological studies have documented that risk factors including smoking and the biochemical profile are responsible for the development of acute myocardial infarction (AMI). Psychological factors ...
Hueb Whady - - 2010
The MASS IV-DM Trial is a large project from a single institution, the Heart Institute (InCor), University of São Paulo Medical School, Brazil to study ventricular function and coronary arteries in patients with type 2 diabetes mellitus. The study will enroll 600 patients with type 2 diabetes who have angiographically ...
Sims Michelle M School for Health, University of Bath, Bath BA2 - - 2010
To measure the short term impact on hospital admissions for myocardial infarction of the introduction of smoke-free legislation in England on 1 July 2007. An interrupted time series design with routinely collected hospital episode statistics data. Analysis of admissions from July 2002 to September 2008 (providing five years' data from ...
Rabi Doreen M - - 2010
BACKGROUND: Low income is associated with adverse cardiovascular outcomes. Diabetes is more prevalent among low income groups, and low income patients with diabetes have been shown to have a greater burden of cardiovascular risk factors and worse cardiovascular outcomes. The objective of this study was to determine whether income status ...
Van Dreden Patrick - - 2009
Several studies have indicated an association between haemostatic markers and acute myocardial infarction, but few or no studies refer to their activity. We studied plasma levels of 10 coagulation factors (fibrinogen, protein C, protein S, von Willebrand factor, D-dimers, factor VIIa, free tissue factor pathway inhibitor, tissue-type plasminogen activator, plasminogen ...
Pei Fang - - 2009
BACKGROUND: There is growing evidence that coronary atherosclerosis and its most severe phenotype, myocardial infarction (MI), are chronic inflammatory diseases. Interleukins are important mediators and modulators of inflammation. The His161Arg polymorphism in the gene encoding of IL-17F has recently been consistently found to be associated with chronic inflammatory disorders. In ...
Leineweber C - - 2011
Background Covert coping with unfair treatment at work-occurring when an employee does not show the "aggressor" that he/she feels unfairly treated-has been found to be associated with cardiovascular risk factors. This study examined whether covert coping also predicts incident coronary heart disease. Methods A prospective cohort study (the WOLF Stockholm ...
Kawecki Damian - - 2009
The aim of the study was to compare the course of myocardial infarction in women versus men in Upper Silesia, an industrial region in the south of Poland. The study comprised 1003 patients with either ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI). The patients were divided into group ...
Cengel A - - 2009
An increasing number of patients under 40 years of age are being hospitalized with the diagnosis of acute myocardial infarction. This is partly due to the increased prevalance of risk factors for atherosclerosis in the younger age group; especially increased incidence of impaired fasting glucose, high triglyceride, low high-density lipoprotein ...
Thiengburanatham Sanya - - 2009
Hyperhomocysteinemia and other major cardiovascular risk factors are associated with increased vascular oxidative stress. To access the effects preoperative plasma homocysteine levels and other atherosclerotic risk factors on myocardial ischemia-reperfusion injury after conventional coronary artery bypass, 213 patients with normal renal function were enrolled prospectively. Cardiac troponin T was measured ...
Lightwood James M JM Department of Clinical Pharmacy, University of California, 3333 California St, Suite 420, San Francisco, CA 94118, USA. - - 2009
The estimated effects of recent pubic and workplace smoking restriction laws suggest that they produce significant declines in community rates of heart attack. The consistency of these declines with existing estimates of the relative risk of heart attack in individuals attributable to passive smoking exposure is poorly understood. The objective ...
Williams Paul T PT Life Sciences Division, Lawrence Berkeley National Laboratory, Donner Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, United States. - - 2010
One-half of Americans currently meet guideline physical activity levels. For these individuals, exceeding guideline levels may provide additional health benefits. Incident physician-diagnosed myocardial infarction and angina, revascularization procedures (CABG, PTCA), and ischemic heart disease deaths during 7.7-year follow-up were compared to baseline usual distance run in 35,402 male runners. Men ...
Heide Steffen - - 2009
OBJECTIVE: The association of apoE polymorphism and coronary heart disease has been examined in numerous clinical studies. However, there are only very few autopsy studies on this topic, there having been none in Germany for instance. METHODS: In a retrospective study, we examined 121 cases where the autopsy revealed premature ...
Norekvål Tone M - - 2010
AIMS: To determine the relationships between different sense of coherence levels and quality of life, and in older female myocardial infarction survivors; to investigate how socio-demographic, clinical characteristics, sense of coherence self-reported symptoms and function affect quality of life; and to determine whether sense of coherence and quality of life ...
Grover Gurprit - - 2009
In this article an attempt has been made to investigate the 10-year trend of cardiovascular risk factors and common heart related sickness including angina, arrhythmias and congestive heart failure, and to study the impact of cardiovascular risk factors and heart related sickness on time between two acute myocardial infarctions. Chi-square ...
Maddox Thomas M - - 2009
PURPOSE OF REVIEW: Adherence to secondary prevention medications among patients with coronary artery disease is essential in minimizing risks of recurrent myocardial infarction and mortality. Despite its importance, nonadherence remains a significant problem among this population, and a variety of studies have sought to determine its prevalence, contributing factors, and ...
Chikamori Taishiro - - 2009
Clinical features of ischemic heart disease in the elderly are different from those in non-elderly patients. The prevalence of female patients, hypertension and co-morbidity was higher in the elderly than in non-elderly patients. Atypical clinical presentation should be taken into consideration, particularly in patients with acute coronary syndrome, because early ...
Bhoomi Reddy - - 2009
INTRODUCTION: Acute myocardial infarction is commonly known as heart attack. It is a multifactorial disease influenced by environmental and genetic factors.The objective of the present study was to investigate the association of the angiotensin II type 1 receptor gene A/C polymorphism in South Indian myocardial infarction patients.Subjects and methods. The ...
Georgoulias Panagiotis - - 2009
Coronary artery disease is associated with multiple genetic and environmental risk factors. In this study, we evaluated the correlation of angiotensin l-converting enzyme (ACE) (I/D) and ApoE gene polymorphisms (E2, E3, E4 and g.-219G/T) with myocardial perfusion. We examined 410 patients using exercise-rest myocardial perfusion single photon emission computed tomography ...
Koch Werner - - 2011
A recent survey of 11,053 single nucleotide polymorphisms from 6891 genes suggested that the risk of myocardial infarction was related to specific genes so far not linked with atherosclerotic diseases. The genes encode the cytoskeletal protein palladin (PALLD), a receptor tyrosine kinase (ROS1), a taste receptor (TAS2R50), an olfactory receptor ...
de Laat Bas - - 2009
von Willebrand factor (VWF) serves as adhesive surface for platelets to adhere to the vessel wall. We have recently found that beta2-glycoprotein I is able to inhibit platelet binding to VWF, indicating a role in the pathophysiology of arterial thrombosis. In the present study, we investigated whether differences in beta2-glycoprotein ...
Tolstrup Janne S - - 2009
BACKGROUND: The risk of myocardial infarction is lower among light-to-moderate alcohol drinkers compared with abstainers. We tested associations between alcohol intake and risk of myocardial infarction and risk factors and whether these associations are modified by variations in alcohol dehydrogenases. METHODS AND RESULTS: We used information on 9584 men and ...
van Straten Albert H M - - 2010
Various definitions of impairment of renal function after coronary artery bypass grafting (CABG) are used in the literature. Depending on the definition, several risk factors are identified. We analysed our data to determine the risk factors for postoperative deterioration of the creatinine clearance of 10% or more. All patients undergoing ...
Pestana Carolina I - - 2009
The most common genetic defect associated with deep vein thrombosis (DVT) is a mutation in the Factor V gene (G1691A), known as Factor V Leiden (FVL). We investigated the genotypes for FVL in 571 individuals in Venezuela: 208 patients with DVT, 175 patients with acute myocardial infarction, 54 patients with ...
Godkar Darshan - - 2009
We describe the case of a 51-year-old female with no risk factors for coronary artery disease who had an episode of a non-ST-elevation myocardial infarction in association with an overdose of Venlafaxine. Cardiac catheterization revealed normal coronary arteries. Because no other obvious exacerbating factors for ischemia were observed, we assume ...
Bhardwaj Rajeev - - 2009
BACKGROUND: Cardiovascular disease has emerged as a major health burden worldwide. There is no study in Himachal about the prevalence of coronary heart disease (CHD), hence the purpose of the study. MATERIAL AND METHODS: Population based study was done in three different villages of different districts of Himachal Pradesh. The ...
Rassi Anis A - - 2009
Chagas heart disease (CHD) results from infection with the protozoan parasite Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a substantial public health burden due to high morbidity and mortality. CHD is also the most serious and frequent manifestation of chronic Chagas disease and appears ...
Thøgersen Anna M - - 2009
The objective of this study was to determine whether a first myocardial infarction leads to increased plasma levels of hemostatic factors and high sensitive C-reactive protein (hs-CRP) and whether the association between theses biomarkers and myocardial infarction was greater at follow-up compared with baseline. Of more than 36,000 persons screened ...
McCarey D - - 2009
Cardiovascular co-morbidity is now a recognised complication of chronic inflammation and an elevated acute phase response predisposes to hypertension, stroke and myocardial infarction. Dyslipidaemia is a feature of inflammatory joint diseases and is closely related to elevated CRP and Il-6 levels. Rheumatoid arthritis (RA) has an increased standardised mortality ratio ...
Grammer Tanja B - - 2009
This study examined the superoxide dismutase 3 (SOD3) R231G polymorphism in relation to the severity of coronary artery disease (CAD) and the risk of myocardial infarction (MI) in 3211 individuals; 94.4% of study participants were homozygous for SOD3 231RR and 5.5% were heterozygous for SOD3 231RG. The odds ratios of ...
Palatini Paolo - - 2009
A number of epidemiologic studies and several experimental lines of research point to high heart rate as a main risk factor for cardiovascular disease. However, translating research into clinical practice has been a challenge throughout medical history. From the present symposium, it appears clear that this is particularly the case ...
Burchardt Pawel - - 2009
Insulin-like growth factor-1 (IGF-1) plays an important role in arterial homeostasis. Its properties seem to depend on circulating IGF-1 level changes. The various IGF-1 levels are caused by varied expression of IGF-1 gene, due to the polymorphic structure of IGF-1 gene or its regulatory sequences. We examined the P1 promoter, ...
Rassi Anis A - - 2009
Chagas heart disease (CHD) results from infection with the protozoan parasite Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a substantial public health burden due to high morbidity and mortality. CHD is also the most serious and frequent manifestation of chronic Chagas disease and appears ...
Cluett Christie C Peninsula Medical School, Exeter, United - - 2009
A common variant at chromosome 9p21 (tagged by the rs1333049 or rs10757278 single-nucleotide polymorphism) is strongly associated with myocardial infarction and major arterial aneurysms. An association with peripheral arterial disease (PAD) was also reported in a sample younger than 75 years, but this disappeared on removal of respondents with a ...
Golestaneh Ladan - - 2009
We describe the case of a young man with prolonged and severe chyluria from a previous parasitic infection. He presented with an acute myocardial infarction most likely secondary to increased clotting tendency. He had a spontaneously formed blood clot in his left anterior descending coronary artery. In the setting of ...
Bui Quang T - - 2009
Atherosclerosis is now recognized as an inflammatory/immunomodulatory reaction to the presence of oxidized low-density lipoproteins within the arterial wall, often times in the setting of such risk factors as family history, hypercholesterolemia, high blood pressure, diabetes mellitus and smoking. The progression to high-risk lesions such as thin-fibrous cap atheromas results ...
Gluba Anna A Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, Poland. - - 2009
Nitric oxide (NO) produced by endothelial nitric oxide synthase (eNOS) is a potent vasodilator. Several polymorphisms in the eNOS gene have been described, some of them being linked with the increased risk of cardiovascular disease, coronary heart disease (CHD), and coronary spasm. We studied 3 polymorphisms within the gene of ...
Zhang Hai-Feng - - 2009
The CD14 gene C-260T polymorphism has been reported to be associated with ischemic heart disease, but results were conflicting. To evaluate the role of the CD14 C-260T polymorphism in ischemic heart disease, we performed meta-analyses of all available data. Comprehensive searches for studies on the association between the genotypes (CC, ...
Schettert Isolmar T - - 2010
INTRODUCTION: Association between ADAMTS13 levels and cardiovascular events has been described recently. However, no genetic study of ADAMTS13 in coronary patients has been described. MATERIALS AND METHODS: Based on related populations frequencies and functional studies, we tested three ADAMTS13 polymorphisms: C1342G (Q448E), C1852G (P618A) and C2699T (A900V) in a group ...
Henareh Loghman - - 2009
BACKGROUND AND AIM: Previous studies have shown that a decreased fibrinolytic activity or a hyperactivated coagulation system increase the risk of myocardial infarction. The aim of this study was to investigate the relationship between the presence of atherosclerotic lesions and coagulation and fibrinolysis factors and high sensitivity CRP (hs-CRP) in ...
Willershausen Brita - - 2009
INTRODUCTION: In patients with cardiovascular diseases several risk factors such as high blood pressure, diabetes, smoking and drinking habits, genetic disposition, and chronic inflammation must be considered. The aim of this study was to investigate whether there is a correlation between dental origin infections and the presence of an acute ...
Meltzer Mirjam E - - 2009
BACKGROUND: Studies on the relation between thrombin activatable fibrinolysis inhibitor (TAFI) and arterial thrombosis have produced conflicting results. TAFI regulates fibrinolysis, but other roles of this inhibitor, including anti-inflammatory properties, have also been demonstrated. DESIGN AND METHODS: We investigated the association between TAFI activity and the risk of myocardial infarction. ...
Prasad Sandhir B - - 2010
The metabolic syndrome (MS) is a novel risk factor for coronary artery disease. The International Diabetes Federation (IDF) re-definition of MS lists obesity as the essential feature of MS. We determined the presence of MS by this obesity-centric definition in 107 consecutive patients with acute myocardial infarction. Our key findings ...
Eddy David M - - 2009
Performance measures and guidelines encourage physicians to advise smokers to quit. The effect of these efforts on the morbidity, mortality, and cost of cardiovascular disease is not known. This article analyzes the effects of offering smoking cessation advice in the US population. The Archimedes model is used to simulate several ...
Kotseva Kornelia - - 2009
BACKGROUND: The first and second EUROASPIRE surveys showed high rates of modifiable cardiovascular risk factors in patients with coronary heart disease. The third EUROASPIRE survey was done in 2006-07 in 22 countries to see whether preventive cardiology had improved and if the Joint European Societies' recommendations on cardiovascular disease prevention ...
Greif Martin - - 2009
OBJECTIVES: Pericardial fat as a visceral fat depot may be involved in the pathogenesis of coronary atherosclerosis. To gain evidence for that concept we sought to investigate the relation of pericardial fat volumes to risk factors, serum adiponectin levels, inflammatory biomarkers, and the quantity and morphology of coronary atherosclerosis. METHODS ...
- - 2009
We conducted a genome-wide association study testing single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) for association with early-onset myocardial infarction in 2,967 cases and 3,075 controls. We carried out replication in an independent sample with an effective sample size of up to 19,492. SNPs at nine loci reached ...
Thompson D R - - 2009
1. The Chinese version of the 27-item MacNew health-related quality of life (HRQL) questionnaire is a valid, reliable and responsive core coronary heart disease (CHD)-specific HRQL measure. It can be used to compare the health outcomes, burdens of illness, and treatment effectiveness in pure or mixed populations of patients with ...
Hsu Lung-An - - 2010
A 21-bp deletion mutation of the exon 11 of the myocyte enhancer factor-2A (MEF2A) gene was shown to cause familial coronary artery disease. This finding raises the possibility that MEF2A variants may contribute to the risk of coronary artery disease. In total, 258 patients with coronary artery disease and 258 ...
Trzos Ewa - - 2009
An estimated 6 to 10% of myocardial infarctions occur in patients under the age of 45. Usually this applies to men, but an increasing prevalence is being observed among women. Atherosclerosis, often one vessel disease, is the main cause. The presence of classic risk factors affects the dynamics of coronary ...
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