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Asai Tohru - - 2012
We introduce a novel technique of ventricular septal defect (VSD) closure through right ventricular incision and through the VSD. It should provide extended and better-anchored coverage of the VSD margin and create a completely leak-free "sandwich" double patch by using large interrupted horizontal mattress sutures only, with no incision in ...
McAlister Blair S - - 2012
Atrial fibrillation is the most common complication occurring after coronary artery bypass graft surgery. The purpose of this article was to examine the incidence of, risk factors related to, and complications caused by postoperative atrial fibrillation. The pathophysiology and treatment of atrial fibrillation and postoperative atrial fibrillation will also be ...
Kumar A Umesh - - 2012
Congenital complete heart block could be absolutely asymptomatic. Increased awareness of suspecting an atrioventricular heart block in patients with slow heart rate and electrocardiograph examination will ensure recognition of this problem. The possibility of sudden cardiac death in these patients should not be forgotten. The goal in the peri-operative anaesthetic ...
Dehghani Hossein - - 2012
Ostium secundum atrial septal defect (ASD) is a common congenital heart defect. The adverse prognosis of untreated ASD diagnosed in childhood is well studied and percutaneous device closure of these ASDs has evolved to become the standard of care in both pediatric and young adult populations. There is a growing ...
Kaya Yuksel - - 2012
Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on brain natriuretic peptide levels. Methods. Between 2008 and 2011, 23 patients ...
Katsanos Konstantinos - - 2012
To date, most animal studies of myocardial ischemia have used open-chest models with direct surgical coronary artery ligation. We aimed to develop a novel, percutaneous, minimally-invasive, closed-chest model of experimental myocardial infarction (EMI) in the New Zealand White rabbit and compare it with the standard open-chest surgical model in order ...
Kumar Sudeep - - 2012
Penetrating chest trauma can cause a wide variety of cardiac injuries, including myocardial contusion, damage to the interventricular septum, laceration of the coronary arteries, and free-wall rupture. Herein, we describe the case of a 21-year-old man who presented with congestive heart failure, which was secondary to an old myocardial infarction ...
Tarkowska Agata - - 2012
Heart diseases are a significant cause of morbidity and mortality in newborns. Diagnostic methods are often not sufficient or, in many cases, cannot be used. There is a great advance in medical knowledge concerning biomarkers in the diagnosis of circulatory system in adult patients. Among them, cardiac troponins play the ...
Bai Wenjuan - - 2012
We sought both to evaluate the clinical value of transesophageal echocardiography in minimally invasive surgical closure of ventricular septal defects and to evaluate the feasibility, safety, and efficacy of the surgical occlusion procedure. We selected 49 pediatric patients who had perimembranous ventricular septal defects as determined by preoperative transthoracic echocardiographic ...
Paraskevas Kosmas I - - 2011
Like the earlier multicenter General Anesthesia (GA) versus Local Anaesthesia (LA) anesthesia for carotid surgery (GALA) trial, a recent independent study showed no difference in transient ischemic attack, stroke, myocardial infarction, and death rates between carotid endarterectomy (CEA) performed under LA compared with GA. Besides these outcomes, however, several additional ...
Riha H - - 2011
Inhalational anesthetics have demonstrated cardioprotective effects against myocardial ischemia-reperfusion injury. Clinical studies in cardiac surgery have supported these findings, although not with the consistency demonstrated in experimental studies. Recent investigations have questioned the advantages of inhalational over intravenous anesthetics with respect to cardiac protection. Ketamine has been shown to be ...
Langenbacher Adam D AD Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, - - 2012
Na(+),K(+) ATPase pumps Na(+) out of and K(+) into the cytosol, maintaining a resting potential that is essential for the function of excitable tissues like cardiac muscle. In addition to its well-characterized physiological role in the heart, Na(+),K(+) ATPase also regulates the morphogenesis of the embryonic zebrafish heart via an ...
Mishra Manisha - - 2011
Heart failure, including myocardial infarction, is the leading cause for death and the incidence of cardiovascular diseases is predicted to continue to rise worldwide. In the present study we investigated the whole heart proteome profile of transgenic p60-Transcription Regulator Protein (p60TRP) mice to gain an insight into the molecular events ...
Liu David X - - 2012
A 6-year-old male India-origin Rhesus macaque (Macaca mulatta) presented with thin body condition and muscular atrophy. Thoracic auscultation revealed a grade VI/VI pansystolic murmur bilaterally. Radiographs showed cardiomegaly with significant left atrial and biventricular enlargement, a dilated pulmonary artery, and hepatomegaly. Electrocardiogram revealed a normal sinus rhythm interspersed with ventricular ...
Bongartz Lennart G - - 2012
Coexistence of chronic kidney disease (CKD) and heart failure (HF) in humans is associated with poor outcome. We hypothesized that preexistent CKD worsens cardiac outcome after myocardial infarction, and conversely that ensuing HF worsens progression of CKD. Subtotally nephrectomized (SNX) or sham-operated (CON) rats were subjected to coronary ligation (CL) ...
Raja Shahzad G - - 2011
Ventricular septal defect closure with a fenestrated patch is a recognized rescue maneuver to decrease the risk of right ventricular failure after complete repair in patients with pulmonary atresia. If the fenestration needs surgical closure, severe calcification of the patch may make it extremely difficult. We describe the closure of ...
Kim Eun Young EY Program in Genes and Development, The University of Texas Health Science Center at Houston, - - 2012
Sumoylation is a posttranslational modification implicated in a variety of cellular activities, and its role in a number of human pathogeneses such as cleft lip/palate has been well documented. However, the importance of the SUMO conjugation pathway in cardiac development and functional disorders is newly emerging. We previously reported that ...
Lockhart Cj - - 2011
Complex atrial septal anatomy can continue to present a challenge for transcatheter closure. We present the successful use of overlapping GORE® HELEX atrial septal defect occluders in an adult patient with 5 distinct fenestrations in an aneurismal septum and how 3D echo can aid device positioning. © 2011 Wiley-Liss, Inc.
Rao Nageswar - - 2012
Accessory mitral valve tissue (AMVT) is a rare congenital anomaly of endocardial cushion. Usually, it arises from the anterior mitral leaflet and causes the left ventricular outflow tract obstruction. We report here the first and a rarest presentation of the AMVT in a 19-year old female patient diagnosed to have ...
Uchida Mio - - 2011
Myocardial Mass in Sarcoidosis. Sarcoidosis is a granulomatous disease that may involve multiple organ systems. The prognosis of sarcoidosis is influenced by the presence and severity of cardiac lesions. Thinning of the wall in the ventricular septum has often been reported, whereas an interventricular septal mass is rare. We describe ...
Quintana-Villamandos B - - 2011
We describe the placement of a left ventricular assist device (LVAD) in a pig with spontaneously occurring atrial septal defect (ASD) (incidental finding) that created a right-left cardiac shunt, with subsequent severe hypoxaemia. Early diagnosis was critical in order to prevent end-organ damage due to hypoxaemia. Adequate monitoring alerted us ...
Wahab Hussien Abdul - - 2011
We report on a new technique "using a partially inflated balloon through the atrial septal defect" to prevent prolapse of the left atrial disk of the Amplatzer septal occulder in large atrial septal defects (ASDs). Two patients underwent successful closure of their ASDs using this new technique. © 2011 Wiley-Liss, ...
Jin Youpeng - - 2011
OBJECTIVE: To describe the evolution of ventricular septal defects in infants from intra-uterine diagnosis to the age of 3 years or until documented echocardiographic closure of the defect, as well as any relationship between closure rate, time and foetal echocardiographic features. METHODS: Between January, 2004 and December, 2006, 268 cases ...
Calvo I - - 2011
This report describes a myocardial transdiaphragmatic foreign body as a consequence of a suspected cranial migration of a sewing needle from the stomach of a dog. Surgical removal of myocardial transdiaphragmatic foreign bodies may be associated with significant haemorrhage that requires immediate surgical action, so direct visualisation of the retrieval ...
Miyazaki Takako - - 2011
Treatment of prosthetic patch endocarditis after closure of a ventricular septal defect is challenging. It is essential to reduce inflammation and prevent recurrence of endocarditis. We report a successful case of reclosure of a ventricular septal defect using an autologous atrial septal patch taken from the fossa ovalis. There were ...
Gajjar Trushar P - - 2011
Abstract  Coronary sinus type of atrial septal defect (ASD CS) is a rare cardiac anomaly and is rarely diagnosed by only transthoracic echocardiography prior to surgical operation. We now describe a technique to treat this defect with the aid of two-dimensional echocardiography, which prevents trauma to the conduction system and ...
Piantedosi Diego - - 2011
A rare association between situs inversus totalis (SIT), restrictive ventricular septal defect, severe subaortic stenosis, and tricuspid dysplasia was observed in an adult mixed-breed dog. Primary ciliary dyskinesia and Kartagener's syndrome were excluded. After 15 mo the dog died suddenly. The association between SIT and congenital heart diseases is discussed.
Elmagrpy Z - - 2011
Children with Down syndrome (DS) have about a 40 to 50% incidence of congenital heart disease (CHD). The objectives of this study were to evaluate the distribution and frequency of CHD patterns in Libyan children with DS. All patients with DS who were referred to the cardiology clinic between January ...
Kazui Toshinobu - - 2011
Septal hyper-contractility is thought to be the principal cause of significant left ventricular outflow tract obstruction (LVOT) and systolic anterior motion (SAM) of the mitral valve by making the distance between the mitral valve and papillary muscle shorter. A seven-year-old patient with severe hypertrophic obstructive cardiomyopathy underwent direct interventricular septal ...
Crossett Marcus Peter - - 2011
CT myocardial perfusion imaging is an emerging CT application using density measurements of contrast-enhanced left ventricular (LV) myocardium. Using a 320-MDCT we have consistently observed lower Hounsfield unit (HU) values in the lateral LV myocardium, potentially mimicking perfusion defects. This study aimed to evaluate contrast-enhancement patterns of the LV myocardium ...
Nissen Jakob Dahl - - 2011
ABSTRACT: Animal models of pacing-induced heart failure (HF) are often associated with high acute mortality secondary to high pacing frequencies. The present study therefore exploits lower frequency left ventricular (LV) pacing (300bpm) in rabbits for 11 weeks to produce chronic HF with low acute mortality, but profound structural, functional, and ...
Hanninen Mikael - - 2011
While atrial septal defect (ASD) closure is known to improve morbidity and mortality in children and adults, data are only beginning to emerge about its role in elderly cohorts. The goals of this study were to compare outcomes after device or surgical closure of ASDs in the elderly, and to ...
Moreno Nuno - - 2011
The ventricular septal rupture is an uncommon complication of myocardial infarction (MI) with a reported incidence of 0.2% in the thrombolytic era. The outcome remains extremely poor, and surgical defect closure still remains the only therapeutic option improving survival. There are single reports based on a small series of case ...
Knecht Kenneth R - - 2011
Atrial septal dissection is a rare entity usually seen after surgical mitral valve repair, myocardial infarction, or endocarditis. This is a report of an atrial dissection in a young girl found on routine follow-up echocardiography after repair of atrial and ventricular septal defects. No identifiable predisposing risk was found prior ...
Chaudhry Tauseef Asma - - 2011
To determine the frequency of various types of ventricular septal defects (VSD) and associated complications in local paediatric population. A cross sectional descriptive study was conducted on children undergoing echocardiography in a single centre from January 2006 to December 2009 at Paediatric Cardiology Department, Ch. Pervaiz Elahi Institute of Cardiology ...
Yu Jian-Bo - - 2011
To determine the effect of sevoflurane combination with epidural anesthesia on myocardial injury in patients with coronary artery disease (CAD) undergoing non-cardiac surgery The investigation was performed in TianJin NanKai Hospital, TianJin, China from November 2009 to March 2010. Eighty patients with CAD undergoing elective abdominal surgery were randomized into ...
Konopka Anna - - 2011
We report the case of a 70-year-old woman with ST-segment elevation myocardial infarction of the anterior wall, complicated by ventricular septal rupture (two septal defects - VSDs) with symptoms of cardiogenic shock. After 6 weeks of conservative treatment with inotropes and intra-aortic balloon support, the patient underwent surgical repair of ...
Sadler T W - - 2011
Several epidemiological investigations have shown an association between congenital heart defects and the selective serotonin reuptake inhibitor (SSRI) class of antidepressants. At first glance this association may not seem to make biological sense, especially since, in many cases, serotonin is thought of as a neurotransmitter involved in signaling between neurons. ...
Lang Di D Department of Biomedical Engineering, Washington University in St Louis, MO 63130, - - 2011
Sinoatrial node is responsible for the origin of the wave of excitation, which spreads throughout the heart and orchestrates cardiac contraction via calcium-mediated excitation-contraction coupling. P wave represents the spread of excitation in the atria. It is well known that the autonomic nervous system controls the heart rate by dynamically ...
Carcano Carolina - - 2011
In this case Cardiac CT angiography has been the tool for evaluation of Atrial septal aneurysm. This cardiac malformation is well identified by echocardiographic techniques and cardiac-MRI sequences. Clinical significance due to left atrial dysfunction and increased thrombo-embolic risk has been described independently and in association to cardiac wall defects ...
Harvey Richard - - 2011
The paper by Kelly et al., from Margaret Buckingham's group at the Pasteur Institute in Paris, changed the way we think about the developing mammalian heart, as well as the origins of congenital heart disease. Prior to this work, classical studies showing that the heart tube grows in part by the ...
Parizkova Barbora - - 2011
New technologies are being introduced every day in the perioperative setting and perioperative practitioners will need to become increasingly familiar with transoesophageal echocardiography (TOE). TOE is used as a diagnostic tool during cardiac surgery in the operating theatre to direct the surgical procedure and to detect acute complications. TOE is ...
Yalçın Yalım - - 2011
Postmyocardial infarction ventricular septal defect (VSD) carries a high mortality and, even after successful surgery, residual defect is common. A 75-year-old woman was admitted with the diagnosis of hyperacute anterior myocardial infarction. Primary percutaneous intervention was performed by stenting of a totally obstructed segment in the proximal left anterior descending ...
Stoker Thijs - - 2011
We describe two cases in which a biventricular implantable cardioverter defibrillator for cardiac resynchronization therapy had to be placed on the right side due to unsuitability of the left subclavian vein. Endocardial implantation of a left ventricular lead through the coronary sinus was previously attempted but was unsuccessful. Implantation of ...
Cho Jung Sun - - 2011
A 56-year-old male presented with resting dyspnea and chest discomfort for several years. During transthoracic and transesophageal echocardiography, a spontaneously healed membranous type ventricular septal defect (VSD) with malaligned interventricular septal wall, aneurysmal changes, a subaortic ridge and a double-chambered right ventricle (DCRV) was observed. When combined with DCRV, VSD ...
Shen Deliang - - 2011
Cardiac dysfunction following acute myocardial infarction is a major cause of advanced cardiomyopathy. Conventional pharmacological therapies rely on prompt reperfusion and prevention of repetitive maladaptive pathways. Keratin biomaterials can be manufactured in an autologous fashion and are effective in various models of tissue regeneration. However, its potential application in cardiac ...
Perloff Joseph K - - 2011
Dextrocardia was known in the 17th century and was 1 of the first congenital malformations of the heart to be recognized. Fifty years elapsed before Matthew Baillie published his account of complete transposition in a human of the thoracic and abdominal viscera to the opposite side from what is natural. ...
Callaghan Michael A - - 2011
A 15 month old boy with a ventricular septal defect (VSD) underwent percutaneous device closure of the VSD. Five days later he collapsed; on arrival to hospital he was asystolic and received prolonged cardio-pulmonary resuscitation (CPR) with intermittent return of spontaneous circulation (ROSC). He had recurrent episodic complete heart block ...
Hayabuchi Yasunobu - - 2011
BACKGROUND: The aim of this study was to evaluate functional differences between the left and right sides of the ventricular septum in children with right ventricular overload. METHODS: Radial, longitudinal, and circumferential strain on both sides of the ventricular septum were compared using speckle-tracking echocardiography in patients with preoperative atrial ...
Kula Serdar - - 2011
Objective:  The aim of this study was to assess the prevalence of persistent left superior vena cava (PLSVC) in patients with all types of congenital heart defects and to determine the congenital heart anomalies accompanying PLSVC. Methods:  The present study is based on a retrospective review of 1205 children who ...
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