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Pangonytė, D.
Both myocardial extracellular matrix as a whole and the fibrillar collagen network can alter in response to environmental stimuli such as ischemia. The aim of the study was to evaluate changes of the fibrillar collagen network in chronic ischemic myocardium and in cases of its regional losses. The percentage volume, ...
Alexander Sarah S Division of Cardiology, Rush University Medical Center, Chicago, IL, - - 2015
Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is commonly used in risk assessment, as an abnormal scan predicts a multifold increase in cardiac risk. Recent studies have showed that application of the appropriate use criteria (AUC) sharpens the prognostic value of SPECT-MPI, while inappropriate use is clinically ...
Cong Tao T The First Affiliated Hospital of Dalian Medical University, Liaoning, - - 2014
Left ventricular remodeling (LVr) is common after ST-segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the prognostic value of speckle tracking echocardiography (STE) for predicting LVr 6-9 months after late percutaneous coronary intervention (PCI) in patients with STEMI. Patients with first STEMI who accepted late PCI ...
Demirelli Selami S Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, - - 2014
Currently, it remains unclear whether there are differences in the long-term physiologic and adaptive changes in an athlete's heart, varying by the type of exercise undertaken. In this study, we used standard and speckle tracking echocardiography (STE) to evaluate the long-term effects of cardiac remodeling, which persisted many years after ...
Acikel S S Department of Cardiology, Ministry of Health Dışkapı Yıldırım Beyazıt Research and Educational Hospital, 06110, Ankara, Turkey, - - 2014
It has been demonstrated that decreased left ventricular ejection fraction (LVEF) is associated with an increased risk of contrast-induced nephropathy (CIN). In this study, we aimed to assess whether there is a relationship between left ventricular (LV) diastolic dysfunction and renal function decline after coronary angiography (CAG). The study consisted ...
Borowski Andreas A Department of Cardiovascular Surgery, University of Düsseldorf, Düsseldorf, - - 2014
Background The purpose of the study was to assess the degree of myocardial acidosis in patients undergoing elective coronary bypass surgery, in whom intermittent cold-blood cardioplegia (ICBC) was used for myocardial protection. The results of this study are presented in comparison to those of a previous trial conducted by the same ...
Axt-Fliedner Roland R Division of Prenatal Medicine, Department of Obstetrics & Gynecology, Justus-Liebig-University, Giessen, - - 2014
The outcome of patients with HLH is influenced by right ventricular function. The study aimed to investigate, whether differences in right ventricular function of fetuses with HLH may be present during gestation. Prospective study of 14 fetuses with HLH (28 measurements) and 28 normal controls (31 measurements). The two groups ...
Shehata Mohamed M Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, - - 2014
Speckle tracking is integrated into echocardiographic systems for evaluation of left ventricular (LV) function by means of automated function imaging (AFI). This study aimed at evaluating role of AFI-based strain in predicting postpercutaneous coronary intervention (PCI) LV function recovery. Fifty patients with anterior wall myocardial infarction and impaired LV ejection ...
Thind Munveer M Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, - - 2014
We describe a case of hypertrophic cardiomyopathy with mid-left ventricular obstruction and apical aneurysm containing thrombi where live/real time three-dimensional transthoracic echocardiography provided incremental value over two-dimensional echocardiography in assessing the findings.
Kalkan Ali Kemal AK Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Training Hospital, Istanbul, - - 2014
Fragmented QRS (fQRS) arises from impaired ventricular depolarization due to heterogeneous electrical activation of ischemic and/or infarcted ventricular myocardium. The short- and long-term prognostic values of fQRS have been reported for myocardial infarction, heart failure, fatal cardiac arrhythmias, and sudden cardiac death. The aim of this study was to investigate ...
Lupi Alessandro A Hospital Cardiology, "Maggiore della Carità" Hospital, Novara, - - 2014
Aims: To evaluate the prognostic implications of baseline cardiac troponin (cTn) values in the normal range in stable coronary artery disease (CAD) patients successfully treated with percutaneous coronary intervention (PCI). Methods and results: We investigated the correlation between pre-procedural cTnI levels and major clinical adverse events at three years of ...
Hutyra Martin M Department of Internal Medicine 1-Cardiology, Faculty of Medicine and Dentistry, University Hospital, Palacký University, I. P. Pavlova 6, 775 20, Olomouc, Czech - - 2014
Right ventricular (RV) myocardial infarction (MI) is a frequent concomitant of an acute inferior MI. We set out to determine the diagnostic value of speckle tracking echocardiography in comparison with cardiac magnetic resonance (CMR) for RV stunning and scar prediction. 55 patients (66 ± 11 years) with an acute inferior ST elevation MI ...
Reichlin Tobias T Department of Cardiology, University Hospital Basel; Department of Internal Medicine, University Hospital Basel, both - - 2014
High-sensitivity cardiac troponin (hs-cTn) may allow an earlier diagnosis of acute myocardial infarction (AMI). We prospectively enrolled 1148 (derivation cohort) and 517 (external validation cohort) unselected patients presenting with suspected AMI to the emergency department. Final diagnosis was adjudicated by two independent cardiologists. Hs-cTnT was measured at presentation and after ...
Morris Daniel A DA Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany - - 2014
The aim of this multicentre study was to determine the normal range and the clinical relevance of the myocardial function of the left atrium (LA) analysed by 2D speckle-tracking echocardiography (2DSTE). We analysed 329 healthy adult subjects prospectively included in 10 centres and a validation group of 377 patients with ...
Platonov Pyotr G PG Department of Cardiology, Clinical Sciences, Lund University, Lund 22185, Sweden Center for Integrative Electrocardiology at Lund University (CIEL), Lund 22185, Sweden - - 2014
Shortening of atrial refractory period during atrial fibrillation has been considered a hallmark of atrial electrical remodelling. The atrial fibrillatory cycle length, which is intimately related to the atrial fibrillatory rate (AFR), is generally accepted as a surrogate marker for local refractoriness. The value of using AFR to monitor the ...
Költő Gyöngyvér G Kaposi Mór Teaching Hospital, Somogy County, Kaposvar, Hungary. - - 2014
Cardiac involvement is an important determinant of prognosis in systemic sclerosis (SSc). The identification of patients with high risk is of great importance. Our aim was to investigate the diagnostic and prognostic value of circulating concentrations of N-terminal fragments of A- and B-type natriuretic peptides (NT-proANP and NT-proBNP) in patients ...
Mizuno Atsushi A Department of Cardiology, St. Luke's International Hospital, Tokyo, Japan. Electronic address: - - 2014
Contrast-induced acute kidney injury (CI-AKI) after percutaneous coronary intervention in patients with ST-elevation myocardial infarction (STEMI) is a common complication associated with worse outcome. Considering the prognostic predictive value of the red cell distribution width (RDW), we aimed to measure the usefulness of RDW for predicting CI-AKI. All consecutive STEMI ...
Ayça Burak B Department of Cardiology, Bağcilar Education and Research Hospital , Istanbul , Turkey - - 2014
Abstract We assessed the prognostic value of the platelet to lymphocyte ratio (PLR) in primary percutaneous coronary intervention (pPCI). Patients (n = 440) with acute myocardial infarction (AMI) who underwent pPCI were divided into 2 groups: low PLR (<137) and high PLR (>137). "Thrombolysis In Myocardial Infarction" (TIMI) flow grades and Syntax ...
Stankovic Ivan I Department of Cardiology, Clinical Hospital Centre Zemun, Faculty of Medicine, University of Belgrade, Vukova 9, Belgrade 11070, Serbia - - 2014
We sought to determine the prevalence of overt and subclinical LV dysfunction in patients with critical left anterior descending coronary artery (LAD) stenosis but without a history of myocardial infarction and to compare diagnostic value of routine echocardiographic parameters with myocardial strain analysis for detection of critical LAD stenosis. We ...
Toth Gabor G GG From the Cardiovascular Research Center Aalst, OLV-Ziekenhuis, Aalst, Belgium (G.G.T., B.T., F.D.V., L.D.S., S.P., D.R., G.D.G., M.P., E.B., C.V.M., G.R.H., B.D.B., W.W.); University Heart Center Graz, Medical University of Graz, Graz, Austria (G.G.T.); and Weatherhead PET Center, University of Texas Medical School, Houston - - 2014
Fractional flow reserve (FFR) measurement of intermediate coronary stenoses is recommended by guidelines when demonstration of ischemia by noninvasive testing is unavailable. The study aims to evaluate the penetration of this recommendation into current thinking about revascularization strategies for stable coronary artery disease. International Survey on Interventional Strategy was conducted ...
Caselli Stefano S Institute of Sports Medicine and Science, Rome, Italy. Electronic address: - - 2014
Whether morphologic left ventricular (LV) changes in elite athletes are associated with altered diastolic properties is undefined. The aim of this study was to investigate LV diastolic properties in a large population of Olympic athletes compared to untrained controls. A total of 1,145 Olympic athletes (61% men), and 154 controls, ...
Aoki Junya J Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
We investigated whether a computed tomography (CT)-based score could predict a large infarct (≥80 mL) on early diffusion-weighted magnetic resonance imaging (DWI). Acute stroke patients considered for endovascular therapy within 8 hours of the onset of symptoms were included. The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) was determined on noncontrast ...
Searle Julia J Department of Cardiology and Division of Emergency Medicine, Campus Virchow Klinikum (CVK) and Campus Mitte (CCM), Charité Universitätsmedizin Berlin, Germany - - 2014
Combined testing of copeptin and troponin at presentation to the emergency department (ED) has been shown to possess a high negative predictive value (NPV) for ruling out acute myocardial infarction (AMI) in patients with suspected acute coronary syndrome. The aim of this study was to evaluate the diagnostic performance of ...
Szymczyk Ewa E aDepartment of Cardiology, Medical University of Lodz bDepartment of Radiology, Barlicki Teaching Hospital, Medical University of Lodz, - - 2014
To assess whether quantitative resting assessment of local myocardial function by 2D speckle tracking echocardiography may be helpful for the evaluation of myocardial viability in patients after ST-elevation myocardial infarction (STEMI) and for the prediction of left ventricular function recovery after 12-month follow-up. The study group comprised 96 patients with ...
Danad Ibrahim I Department of Cardiology, VU University Medical Center, Amsterdam, the - - 2014
Recent studies have demonstrated improved diagnostic accuracy for detecting coronary artery disease (CAD) when myocardial blood flow (MBF) is quantified in absolute terms, but there are no uniformly accepted cutoff values for hemodynamically significant CAD. The goal of this study was to determine cutoff values for absolute MBF and to ...
Alonso Pau P Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain. Electronic address: - - 2014
Pulmonary regurgitation is a common complication in patients with repaired tetralogy of Fallot or congenital pulmonary stenosis. Electrocardiographic variables have been correlated with parameters used to evaluate right ventricular function. We aimed to analyze the diagnostic value of the width and fragmentation of the electrocardiogram in the identification of patients ...
Zeller Tanja - - 2014
Abstract Background: The 99th percentile of cardiac troponin levels, determined in a reference population, is accepted as threshold for diagnosis of acute myocardial infarction (AMI). However, there is no common consensus of how to define the reference population. The aim of the present study was to determine 99th percentile reference ...
Roghi Alberto A From the *CMR Unit, Department of Cardiology and Cardiac Surgery, Niguarda Ca' Granda Hospital; †Rare Diseases Center, Department of Medicine and Medical Specialities, Ca' Granda Foundation Ospedale Maggiore Policlinico IRCCS; and ‡Department of Clinical Sciences and Community Health, Ca' Granda Foundation Ospedale Maggiore Policlinico IRCCS, University of Milan, Milan, - - 2014
The aim of this study was to compare myocardial T2* assessment with region-based (RB) T2* multiecho technique (CMRtools) with the pixel-wise (PW) inline myocardial T2* mapping (Siemens) in patients with thalassemia major for myocardial iron characterization. Forty-three thalassemia major patients were examined on a 1.5-T scanner using conventional gradient multiecho ...
Bulbul Sen Bilge B Department of Dermatology, Mustafa Kemal University, School of Medicine, Hatay, - - 2014
Psoriasis is an inflammatory disorder, which has been reported to be associated with cardiovascular (CV) risks. Although increased CV risks in psoriasis are well established, there are no data about changes of contraction synchrony in psoriasis. Therefore, we aimed to study the left ventricular (LV) contraction synchrony in patients with ...
Marston Nicholas A NA University of California San Diego, San Diego, CA, - - 2014
The prognostic value of copeptin in acute chest pain is an area of rapid growth and research interest. Copeptin has already established a role in early diagnosis and rule out of acute myocardial infarction, but as its use increases much of the attention has been directed at the prognostic value ...
Kodali Bhavani Shankar BS Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, - - 2014
Capnography continues to be an important tool in measuring expired carbon dioxide (CO2). Most recent Advanced Cardiac Life Support (ACLS) guidelines now recommend using capnography to ascertain the effectiveness of chest compressions and duration of cardiopulmonary resuscitation (CPR). Based on an extensive review of available published literature, we selected all ...
Udholm Sebastian S 1 Department of Cardiothoracic & Vascular Surgery T, 2 Department of Cardiology, Cardiac Imaging Center, Aarhus University Hospital, DK-8200 Aarhus N, Denmark ; 3 Cardiac Imaging Center, Hospital Unit West, - - 2014
Assessment of ischemic but potentially viable myocardium plays an important role in the planning of coronary revascularization. Until now SPECT, PET, and MRI have been used to identify viable myocardium. Computed tomography (CT) is increasingly used to diagnose coronary atherosclerosis. To evaluate the feasibility of CT enhancement as a viability ...
Evensen Kristin - - 2014
Atherosclerosis is the underlying cause of the majority of myocardial infarctions and ischemic strokes. Carotid intima-media thickness (IMT) is a surrogate measure of atherosclerotic cardiovascular disease. Left ventricular (LV) function can be accurately assessed by 2D speckle-tracking strain echocardiography (2D-STE). The aim of this study was to assess the relationship ...
Storrow Alan B AB Dept. of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN. Electronic address: - - 2014
We investigated absolute and relative cardiac troponin I (TnI) delta changes, optimal sampling protocols, and decision thresholds for early diagnosis of myocardial infarction (MI). Serial cardiac biomarker values demonstrating a rise and/or fall define MI diagnosis; however the magnitude of change, timing, and diagnostic accuracy of absolute versus relative (percentage) ...
Meloni Antonella A CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, Pisa 56124, - - 2014
[Formula: see text] multislice multiecho cardiac magnetic resonance (CMR) allows quantification of the segmental distribution of myocardial iron overload (MIO). We evaluated whether a preferential pattern MIO was preserved between two CMR scans in regularly chelated thalassaemia major (TM) patients. We evaluated prospectively 259 TM patients enrolled in the MIO ...
Owais Khurram K Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, - - 2014
Before clinical manifestation of regurgitation, the tricuspid annulus dilates and flattens when right ventricular dysfunction is potentially reversible. That makes the case for a prophylactic tricuspid annuloplasty even in the absence of significant tricuspid regurgitation. Owing to the appreciation of the favorable prognostic value of tricuspid annuloplasty, the geometry of the normal tricuspid ...
Engels Elien B EB From the Departments of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the - - 2014
Chronic heart failure patients with a left ventricular (LV) conduction delay, mostly due to left bundle branch block (LBBB), generally derive benefit from cardiac resynchronization therapy (CRT). However, 30%-50% of patients do not show a clear response to CRT. We investigated whether T-wave analysis of the ECG can improve patient ...
Russo Cesare C Department of Medicine, Division of Cardiology, Columbia University Medical Center, 630 West 168th Street, New York, NY, 10032, - - 2014
Global longitudinal strain (GLS) assessed by speckle-tracking echocardiography has been proposed as a parameter able to reflect early changes in left ventricular systolic function at a stage when left ventricular ejection fraction (LVEF) is still normal. This study aimed at assessing prevalence and prognostic value of left ventricular systolic dysfunction ...
Cho Iksung I Division of Cardiology, Severance Cardiovascular Hospital and Severance Biomedical Science Institute, Yonsei University College of Medicine, Yonsei University Health System, 250 Seongsanno Seodaemungu, Seoul, South Korea Department of Radiology, NewYork-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY, - - 2014
Prior evidence observed no predictive utility of coronary CT angiography (CCTA) over the coronary artery calcium score (CACS) and the Framingham risk score (FRS), among asymptomatic individuals. Whether the prognostic value of CCTA differs for asymptomatic patients, when stratified by CACS severity, remains unknown. From a 12-centre, 6-country observational registry, ...
Storrow Alan B AB Dept. of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: - - 2014
To compare emergency department TnI serial sampling intervals, determine optimal diagnostic thresholds, and report representative diagnostic performance characteristics for early rule-in and rule-out of MI. We prospectively measured TnI (AccuTnI+3™, Beckman Coulter) at serial time intervals in 1929 subjects with chest pain or equivalent ischemic symptoms suggestive of acute coronary ...
Xia Rui R Molecular Imaging Laboratory, Department of Radiology, West China Hospital, Sichuan University, PR China Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, PR - - 2014
The common T2 mapping is not suitable for the use in rat heart with high heart rate, unless data are acquired in multiple cardiac cycles. To evaluate a simplified T2 mapping method for faster assessment of myocardial edema and area at risk in a rat model of myocardial infarction. The ...
Altekin Refik Emre RE Akdeniz University Faculty of Medicine, Department of Cardiology, Antalya, - - 2014
Cirrhosis is associated with certain abnormalities in left ventricular (LV) structure and function. Two-dimensional speckle-tracking echocardiography (2D-STE) enables a rapid and accurate analysis of regional LV systolic mechanics in the longitudinal, radial and circumferential directions. The aim of this study was to precisely assess the differences among the 3 directions ...
Al Moudi Mansour M Department of Medical Imaging and Nuclear Medicine, King Saud Medical City, Riyadh, Saudi Arabia ; Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, GPO Box U1987 Perth, Western Australia 6845, - - 2014
To investigate the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in the assessment of myocardial viability in patients with known coronary artery disease (CAD) when compared to (99m)Tc single photon emission computed tomography (SPECT) and echocardiography, with invasive coronary angiography as the gold standard. Thirty patients with diagnosed ...
van de Hoef Tim P TP AMC Heart Center, Academic Medical Center - University of Amsterdam, Amsterdam, The - - 2014
Aims: We sought to compare the diagnostic accuracy of basal stenosis resistance index (BSR), instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) for stenosis-specific myocardial ischaemia identified by means of a combined reference standard of myocardial perfusion scintigraphy and the hyperaemic stenosis resistance index. Methods and results: BSR and ...
Kono Atsushi K AK Department of Radiology, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan, - - 2014
To evaluate the details of myocardial dysfunction in dilated cardiomyopathy (DCM) patients using tagging images and the correlation of tagging imaging with tissue characteristics. Circumferential strain (Ecc) derived from tagging images was measured in 15 normal (NML) subjects (15 males; mean age 28.5 years) and 12 DCM patients (7 males; mean ...
Fragakis Nikolaos N Third Department of Cardiology, Hippokrateion Hospital, Aristotle University Medical School, Thessaloniki, - - 2014
Currently available agents for pharmacologic management of atrial fibrillation (AF) are limited by their suboptimal efficacy and nonnegligible proarrhythmic risk. Ranolazine (RN) is a novel antianginal agent with increasingly appreciated antiarrhythmic properties that can suppress ventricular and supraventricular arrhythmias including AF. In this review, we describe the electrophysiological properties of ...
Doi Masayuki M Department of Cardiology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, Kagawa 760-8557, Japan. Electronic address: - - 2014
We examined whether early loading of eicosapentaenoic acid (EPA) reduces clinical adverse events by 1month, accompanied by a decrease in C-reactive protein (CRP) values in patients with acute myocardial infarction (MI). Acute MI triggers an inflammatory reaction, which plays an important role in myocardial injury. EPA could attenuate the inflammatory ...
Jhamnani Sunny S Department of Medicine, Division of Cardiology, Georgetown University Hospital/Washington Hospital Center, Washington, DC 20010; Department of Medicine, Division of Cardiology, Yale University School of Medicine, New Haven, CT 06520. Electronic address: - - 2014
Descriptions of the significance of ST segment or QRS abnormalities in myocarditis are limited because documentation of the diagnosis has previously required myocardial biopsy. Late gadolinium enhancement (LGE) and T2 weighted imaging in the midventricular wall on cardiac magnetic resonance imaging (CMRI) has a very good positive predictive value for ...
Korley Frederick K FK Department of Emergency Medicine, Johns Hopkins University School of Medicine, Davis Building, Suite 3220, 5801 Smith Avenue, Baltimore, MD 21209, - - 2014
High-sensitivity troponin (hsTn) assays are used clinically in most parts of the world and are expected to be approved by the US FDA for clinical use in the USA soon. Clinical use of hsTn leads to improvements in the detection of myocardial injury, shorter time to ruling out acute myocardial ...
Saxena Pankaj P Department of Cardiothoracic Surgery, The Alfred Hospital, Melbourne, - - 2014
We report our experience with an adolescent patient who required complex management leading to retransplantation for coronary allograft vasculopathy and also review the role of ventricular assist device support in patients with this clinical entity.
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