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Ziv Ohad O Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, - - 2012
Ventricular arrhythmias in the setting of a healed myocardial infarction have been studied to a much lesser degree than acute and subacute infarction, due to the pericardial scarring, which results from the traditional open-chest techniques used for myocardial infarction (MI) induction. We sought to develop a segmental MI with low ...
Pollak Scott J - - 2012
OBJECTIVE: The objective of this study was to evaluate the use of continuous catheter impedance monitoring prior to ablation to facilitate differentiation of the coronary sinus ostium (CSO) and the middle cardiac vein (MCV) from the right atrial posteroseptal region (RPS). BACKGROUND: Empiric observations have suggested that continuous catheter impedance ...
Farrell David H - - 2012
Abstract γ' fibrinogen is an isoform of fibrinogen that normally constitutes about 7% of total plasma fibrinogen, and arises from an alternative processing event in the γ chain mRNA. γ' fibrinogen is a newly-emerging cardiovascular disease (CVD) risk factor that appears to have an independent association with CVD from that ...
Neuzil Petr - - 2013
CardioARM, a highly flexible "snakelike" medical robotic system (Medrobotics, Raynham, MA), has been developed to allow physicians to view, access, and perform complex procedures intrapericardially on the beating heart through a single-access port. Transthoracic epicardial catheter mapping and ablation has emerged as a strategy to treat arrhythmias, particularly ventricular arrhythmias, ...
Yokokawa Miki - - 2012
BACKGROUND: -Intramural septal idiopathic ventricular arrhythmias have not been described systematically. METHODS AND RESULTS: -In a consecutive group of 93 patients with idiopathic ventricular arrhythmias referred for ablation, the site of origin of ventricular arrhythmias was assessed by activation mapping and pace-mapping. In 7/93 patients (8%), an intramural focus in ...
Mozos Ioana - - 2012
Aim: Ventricular remodeling causes left ventricular hypertrophy (LVH) in myocardial infarction patients. We hypothesized that LVH can be evaluated using isointegral body surface maps. Methods: Thirty-two patients with post-infarction stable chronic heart failure underwent a 64-electrode body surface mapping (isointegral QRS, QRST, ST and STT maps) and 2-D echocardiography. Results: ...
Brisinda Donatella - - 2012
To test the feasibility of a novel method to combine magnetocardiographic (MCG) estimate of ventricular repolarization (VR) and multiple monophasic action potential (MultiMAP) recording in spontaneously breathing rodents with percutaneous sub-xyphoid epicardial placement of a MCG-compatible amagnetic catheter (AC), ten Wistar rats (WRs) and ten guinea pigs (GPs) were studied. ...
Tung Roderick - - 2012
Myocardial scars harbor areas of slow conduction and display abnormal electrograms. Pace-mapping at these sites can generate a 12-lead ECG morphological match to a targeted ventricular tachycardia (VT), and in some instances, multiple exit morphologies can result. At times, this can also result in the initiation of VT, termed pace-mapped ...
Yokokawa Miki - - 2012
BACKGROUND: Post-infarction ventricular tachycardia (VT) typically involves the left ventricular endocardium. Right ventricular involvement in the arrhythmogenic substrate of post-infarction VT is considered unusual. The purpose of this study was to assess the role of right ventricular mapping and ablation in patients with prior septal myocardial infarction. METHODS AND RESULTS: ...
Tai Ching-Tai - - 2012
Background: The detail of biatrial activation during sustained atrial fibrillation (AF) has not been investigated until now. Methods: Five dogs with right ventricular pacing-induced congestive heart failure (CHF) and five normal dogs were included. Biatrial endocardiac mapping was performed using noncontact mapping system. Results: Noncontact mapping of the right atrium ...
Chung Hoe-Hoon - - 2012
Systemic sclerosis (SS) is a connective tissue disease and cardiac involvement is common. Primary cardiac involvement such as conduction system disturbances and arrhythmias can also occur. However, reports of sustained ventricular tachycardia (VT) are rare. We report a case of catheter ablation of sustained ventricular tachycardia in a patient with ...
Kerst Gunter - - 2012
BACKGROUND: Conventional catheter ablation of cardiac arrhythmias is associated with radiation risks for patients and laboratory personnel. However, nonfluoroscopic catheter guidance may increase the risk for inadvertent cardiac injury. A novel radiofrequency ablation catheter capable of real-time tissue-tip contact force measurements may compensate for nonfluoroscopic safety issues. OBJECTIVE: This study ...
Franks Michael J - - 2012
ABSTRACT: Traditionally, the diagnosis of acute myocardial infarction (AMI) in emergency departments is done through an assessment of history and presenting symptoms, 12-lead electrocardiogram (ECG), and cardiac biomarkers. The 12-lead ECG is not highly sensitive for detecting ECG changes, and some infarctions may be missed. Failure to identify patients in ...
Kaneko Yoshiaki - - 2012
A 68-year-old man died a few days after catheter ablation of drug-resistant, monomorphic ventricular tachycardia (VT) complicated with cardiac sarcoidosis. The diagnosis of mitral isthmus VT was made from electrophysiological observations, including electro-anatomical activation and voltage map, pace-mapping, entrainment mapping and ablation outcome. On autopsy of the heart, sarcoidic lesion ...
Houmsse Mahmoud - - 2012
Catheter ablation by radiofrequency (RF) energy has successfully eliminated cardiac tachyarrhythmias. RF ablation lesions are created by thermal energy. Electrode catheters with 4-mm-tips have been adequate to ablate arrhythmias located near the endocardium; however, the 4-mm-tip electrode does not readily ablate deeper tachyarrhythmia substrate. With 8- and 10-mm-tip RF electrodes, ...
Iglesias-Garriz Ignacio - - 2012
Right ventricular systolic dysfunction (RVSD) has been related to prognosis in patients with heart failure (HF) and/or left ventricular systolic dysfunction. However, most of the studies addressing this issue are not large enough, have different inclusion criteria, and use different methods to evaluate RV function to draw definite conclusions. We ...
Kostkiewicz Magdalena - - 2012
Normal exercise SPECT studies are associatedwith a low event rate. The association of the negative SPECTand positive coronary angiography with the results for the longtime follow up was determined. 45 patients were included intothe study. All patients had normal SPECT study and positiveangiography in the ≤ 6 months after SPECT. ...
Selvaraj Raja J - - 2012
A 35 year old female presented with recurrent ventricular tachycardia 5 years after she had undergone surgical repair of double chambered right ventricle. Electroanatomical mapping showed a localised scar in the apex with double potentials and good pace map. Ablation here resulted in non-inducibility of ventricular tachycardia. We hypothesise that ...
Taghavi Sharven - - 2012
Ischemic heart disease, despite advances in treatment, remains the major cause of mortality worldwide. NOGA 3D left ventricular electromechanical mapping allows accurate determination of cardiac function and precise identification of sites of injury. In a porcine model of ischemia-reperfusion injury, we validate the use of the NOGA mapping system for ...
Sadeghi Masoumeh - - 2012
Coronary artery disease (CAD) and myocardial infarction are the most common causes of mortality and morbidity all over the world. Aspirin resistance is an important part of therapeutic failure in patients who experience several atherosclerotic events despite aspirin therapy. Different studies have reported aspirin resistance between 5% and 45% all ...
Guo Xiaogang - - 2012
The function of the repolarization reserve in the prevention of ventricular arrhythmias during cardiac ischemia/reperfusion and the impact of ischemia on slowly activated delayed rectifier potassium current (I(Ks)) channel subunit expression are not well understood. The responses of monophasic action potential duration (MAPD) prolongation and triangulation were investigated following an ...
Vinegoni Claudio - - 2012
To date there is a lack of tools to map the spatio-temporal dynamics of diverse cells in experimental heart models. Conventional histology is labor intensive with limited coverage, whereas many imaging techniques do not have sufficiently high enough spatial resolution to map cell distributions. We have designed and built a ...
Shalganov Tchavdar N - - 2012
Focal right ventricular tachycardia is relatively uncommon. It usually arises from specific anatomic locations. A 59-year-old woman with a structurally normal heart and an automatic cardioverter-defibrillator implanted beforehand presented with drug-resistant incessant ventricular tachycardia for which 1786 anti-tachycardia pacing therapies and 119 shocks had been delivered. Electroanatomical mapping showed focal ...
Reithmann Christopher - - 2011
AimsThe purpose of the study was to evaluate the role of coronary venous mapping to identify epicardial ventricular tachycardia (VT) in patients with structural heart disease.Methods and resultsEpicardial mapping of the electrophysiological substrate through the coronary vein branches using a 2.2F, 16-pole microelectrode catheter was performed in 33 consecutive patients ...
Kozlíková K - - 2011
In this retrospective study we analysed changes of the ST segment in patients with arterial hypertension using multi-lead body surface mapping of the electric heart field as the ST segment often shows non-specific changes and is influenced by many different conditions. We constructed isointegral maps (IIM) of chosen intervals (the ...
Iijima Kenichi - - 2011
A 34-year-old woman presented with idiopathic premature ventricular complex (PVC) and ventricular tachycardia (VT) originating from the area called the left ventricular summit. Radiofrequency (RF) application both through the coronary sinus and to the epicardial surface transiently suppressed the VT/PVC. Radiofrequency with sufficient energy was only applicable from the endocardial ...
El-Damaty Ahmed - - 2011
Left atrial ablation has become more commonplace with the advent of catheter ablation for atrial fibrillation. A number of transseptal sheaths have been produced to enhance safe and efficient catheter manipulation in the left atrium (LA) for these procedures. Some of the sheaths have been subject to recall due to ...
Sayah Sima - - 2011
In this article, we report 2 young patients (a 15-year-old adolescent girl and a 25-year-old man) with drug-refractory palpitations. Admission electrocardiograms showed runs of ventricular tachycardia with left bundle-branch block morphology, left inferior axis, early precordial QRS transition, and positive QRS complex in lead I. In right ventricular mapping, the ...
Yoshida Kentaro - - 2011
The purpose of this study was to assess the prevalence of the re-entry circuit within the interventricular septum in post-infarction patients referred for ventricular tachycardia (VT) ablation. Post-infarction ventricular tachycardia can involve the endocardial myocardium, the intramural myocardium, the epicardium, or the His Purkinje system. Among 74 consecutive patients with ...
Augello Giuseppe - - 2011
Perisinusal atrial tachycardia may represent a challenging situation due to unsustained burst characterizing the arrhythmia, sensitivity to bumping, and potential complications including sinus node ablation. This case describes the use of a noncontact mapping system to map and ablates this arrhythmia. Benefit of this technology is described. (PACE 2011;1-4).
Erdem Alim - - 2011
OBJECTIVE: The difference of the conduction velocity (CV) around the tricuspid valve annulus between the counter-clockwise (CCW) atrial flutter and the clockwise (CW) atrial flutter has not been well clarified. This study was undertaken to evaluate the CV and the conducting area (CA) per millisecond around the tricuspid valve annulus ...
Giaccardi Marzia - - 2011
Situs viscerum inversus totalis (SVIT) is a congenital disorder characterized by mirror reversal of the thoracic and abdominal organs. Different studies have shown that the ablation procedure can be performed without fluoroscopy with safety and effectiveness, in the setting of supraventricular tachycardia. We successfully performed an anatomical map and a ...
Kim Ki-Hun - - 2011
Ablation Catheter Entrapment by Chordae Tendineae. We report on the entrapment of an ablation catheter by chordae tendineae in the mitral valve during radiofrequency (RF) ablation of ventricular tachycardia. The entrapped tip had to be removed via open surgery. Great care must be taken when performing radiofrequency ablation around the ...
Milberg Peter - - 2011
BACKGROUND: Molecular remodelling in heart failure includes slowing of repolarization, leading to proarrhythmia. OBJECTIVE: To evaluate the effects of NCX inhibition on repolarization as a novel antiarrhythmic concept in chronic heart failure (CHF). METHODS AND RESULTS: CHF was induced by rapid ventricular pacing in rabbits. LV function was assessed by ...
Bhargava Kartikeya - - 2011
Entrainment mapping of ischemic ventricular tachycardia at a site in the left ventricle where radiofrequency ablation was successful in terminating the tachycardia revealed a post-pacing interval shorter than the tachycardia cycle length. The reason for the same is explained in the current report.
Thavendiranathan Paaladinesh - - 2012
T2-weighted cardiac magnetic resonance imaging is useful in diagnosing acute inflammatory myocardial diseases, such as myocarditis and tako-tsubo cardiomyopathy (TTCM). We hypothesized that quantitative T2 mapping could better delineate myocardial involvement in these disorders versus T2-weighted imaging. Thirty patients with suspected myocarditis or TTCM, referred for cardiac magnetic resonance imaging, ...
Maul Timothy M - - 2011
The PediVAS blood pump is a magnetically levitated centrifugal pump designed for pediatric bridge-to-decision or bridge-to-recovery in pediatric patients from 3-20kg in weight. In preparation for submission of an investigational device exemption (IDE) application, we completed a final six-animal series of pre-clinical studies. The studies were conducted under controlled conditions ...
Yokokawa Miki - - 2011
BACKGROUND: The value of the 12-lead ECG to identify the exit site of post-infarction ventricular tachycardia (VT) has been questioned. The purpose of this study was to assess the accuracy of a computerized algorithm for identifying a VT exit site based on the 12-lead ECG. METHODS AND RESULTS: In 34 ...
Santilli R A - - 2011
Objectives: To describe the electrocardiographic characteristics of ventricular tachycardia arising from the right ventricular outflow tract and the particular association between this arrhythmia and the presence of localised right ventricular outflow tract enlargement in English bulldogs. Methods: Five English bulldogs were referred with a history of syncope or cardiogenic shock. ...
Martinek Martin - - 2011
Criteria for Epicardial Origin in Ischemic VT. Objectives: We tested proposed algorithms for idiopathic and nonischemic tachycardias for their ability to identify epicardial LV-VT origins. Backgroud: Several ECG features have been reported to identify epicardial origins for left ventricular tachycardias (LV-VTs) in the absence of myocardial infarction. Only limited data ...
Nacif Marcelo Souto - - 2011
To evaluate the relationship between "Look-Locker" (LL) and modified Look-Locker Inversion recovery (MOLLI) approaches for T1 mapping of the myocardium. A total of 168 myocardial T1 maps using MOLLI and 165 maps using LL were obtained in human subjects at 1.5 Tesla. The T1 values of the myocardium were calculated ...
Jang Young-Ho - - 2012
Recent studies have shown that stromal cell derived factor-1 (SDF-1), first known as a cytokine involved in recruiting stem cells into injured organs, confers myocardial protection in myocardial infarction, which is not dependent on stem cell recruitment but related with modulation of ischemia-reperfusion (I/R) injury. However, the effect of SDF ...
Andreu David - - 2011
BACKGROUND: -Scar heterogeneity identified with contrast enhanced-Cardiac Magnetic Resonance (ce-CMR) has been related to its arrhythmogenic potential by using different algorithms. The purpose of the study was to identify the algorithm that best fits with the electroanatomical voltage maps (EAM) to guide ventricular tachycardia (VT) ablation. METHODS AND RESULTS: -Three-dimensional ...
Nakano Emi - - 2011
Identification of Ventricular Outflow Tract Tachycardia. Background: Reentrant ventricular outflow tract (OT) tachycardia is rare in patients with nonischemic heart disease. The mechanism of ventricular tachycardia (VT) arising from the region of the aortic sinus of Valsalva (ASOV) is usually focal, rather than reentrant. Consequently, less is known about reentrant circuits ...
Díaz Infante Ernesto - - 2011
Premature ventricular contractions originating in the right ventricular outflow tract may respond poorly to pharmacological treatment, and ablation using conventional fluoroscopically-guided systems may be complicated by the difficulty in inducing arrhythmias. We describe the use of a non-contact mapping system to ablate difficult-to-induce premature ventricular contractions originating in the right ...
Haas Sebastian - - 2011
BACKGROUND: Robotic-assisted laparoscopic prostatectomy (RALP) is usually performed in steep Trendelenburg position, which can be associated with cardiac impairment due to positioning and capnoperitoneum. This study investigated haemodynamic consequences and cardiac function in this type of surgery and evaluated the hypothesis that steep Trendelenburg position and capnoperitoneum results in haemodynamic ...
Kozlíková K - - 2011
The aim of our work was to study the opposite polarity of the PQ segment to the P wave body surface potential maps in different groups of patients. We constructed isointegral maps (IIM) in 26 healthy controls (C), 16 hypertensives (HT), 26 patients with arterial hypertension and left ventricular hypertrophy ...
Deneke Thomas - - 2011
A novel ablation system consisting of a duty-cycled phased radiofrequency generator and multielectrode mapping and ablation catheters has been introduced to provide ablation therapy in patients with symptomatic atrial fibrillation (AF). Contiguous lesions may be created using anatomically designed ablation catheters maneuvered under fluoroscopic guidance without the use of a ...
Shokrollahi E - - 2011
The arrhythmogenic substrate in patients with prior myocardial infarct (MI) is located at the border zone, BZ. In this study we correlated the BZ identified by two methods: electro-anatomical voltage mapping (EAVM) and a novel MRI method, multi-contrast late enhancement (MCLE). A pre-clinical porcine model with chronic MI was used ...
Valderrábano Miguel - - 2011
Catheter ablation of ventricular tachycardia (VT) can be technically challenging due to difficulty with catheter positioning in the left ventricle (LV) and achieving stable contact. The Hansen Sensei Robotic system (HRS) has been used in atrial fibrillation but its utility in VT is unclear. The purpose of this study was ...
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