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Zhang Li L Lankenau Medical Center, Lankenau Institute for Medical Research, Jefferson Medical College, Philadelphia, Pennsylvania, USA. - - 2014
The ECG is abnormal in most patients with arrhythmogenic right ventricular dysplasia (ARVD). Right ventricular parietal block, reduced QRS amplitude, epsilon wave, T wave inversion in V1-3 and ventricular tachycardia in the morphology of left bundle branch block are the characteristic changes that reflect the underlying genetic predetermined pathology and ...
Johnson Jonathan N JN 1 Department of Pediatrics/Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota, United States of - - 2014
A 10-year-old boy with polyvalvular dysplasia and severe involvement of both atrioventricular valves presented with palpitations. Concern was raised for atrial tachyarrhythmia due to biatrial enlargement; however, ambulatory monitoring discovered a reentrant mechanism. Electrophysiology study revealed atypical atrioventricular nodal reentrant tachycardia involving two components of the slow pathway, with inputs ...
Gottschalk Byron B Division of Cardiology, Kingston General Hospital, Queen's University, Kingston, Ontario, - - 2014
We report a case of a 68-year-old man admitted to the emergency department with syncope preceded by rapid palpitations. His admission ECG demonstrated a sustained ventricular tachycardia (VT) originating from the right ventricular outflow tract (RVOT). This report highlights the importance of distinguishing ventricular tachycardia caused by arrhythmogenic right ventricular ...
Lin Ming-Chih MC 1 School of Medicine, National Yang-Ming University, Taipei, - - 2014
Acute myocardial infarction is rarely reported in children. Most of the cases are secondary to congenital anomalies or Kawasaki disease. Coronary artery total occlusion caused by fibromuscular dysplasia has never been reported in young children. Here we report a case of a 12-year-old boy with fibromuscular dysplasia, who underwent successful ...
Comelli Ivan I University Hospital of Parma, Italy. - - 2014
A paradigmatic case of aborted sudden cardiac death (SCD) in a young man is discussed, mirroring the challenge of diagnosing the various conditions potentially underlying this dramatic condition. Based on the clinical characteristics of our case, presenting some overlapping clinical features common to both the diseases, the discussion will be ...
Elhoury Motea E - - 2013
Geleophysic dysplasia is an extremely rare acromelic skeletal dysplasia resembling lysosomal storage disease. It is characterised by characteristic facial phenotype, short stature, micromelia, joint contracture, and early cardiac valvular involvement. It has been described worldwide in <40 patients. Herein, we describe the cardiac features in three Saudi sisters with proved ...
Kobayashi Taisei - - 2013
Hypertrophic cardiomyopathy (HCM) is histopathologically characterized by myocyte hypertrophy, disarray, interstitial fibrosis, and small intramural coronary arteriole dysplasia, which contribute to disease progression. Longitudinal systolic and early diastolic strain rate (SR) measurements by speckle tracking echocardiography are sensitive markers of regional myocardial function. We sought to determine the association between ...
Iyer V Ramesh - - 2013
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a progressive genetic cardiomyopathy characterized by progressive fatty and fibrous replacement of ventricular myocardium. The clinical presentation is marked by ventricular arrhythmias, some fatal. The disease has evolved from a primary electrical/electrophysiological disorder (in the 1980s-1990s) to a diagnostic imaging conundrum (in the 2000s) ...
Te Riele Anneline S J M - - 2013
In Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C), a normal electrocardiogram (ECG) is considered reassuring. However, some ARVD/C patients with ventricular arrhythmias have a normal ECG. 1) To estimate how often ARVD/C patients with ventricular arrhythmias have a normal ECG during sinus rhythm; and 2) To provide a clinical profile of these ...
Te Riele Anneline S J M - - 2013
The traditional description of the Triangle of Dysplasia in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) predates genetic testing and excludes biventricular phenotypes. We analyzed Cardiac Magnetic Resonance (CMR) studies of 74 mutation-positive ARVD/C patients for regional abnormalities on a 5-segment RV and 17-segment LV model. The location of electroanatomic endo- and ...
Tanawuttiwat Tanyanan - - 2013
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a disease characterized by fibro-fatty replacement of the right ventricular myocardium, generally considered to be based upon variations in desmosomal genes. However, its pathogenesis is not completely clear since myocarditis and high intensity athletics have both been postulated to contribute to the onset and ...
Saprungruang Ankavipar - - 2013
Electrocardiographic feature is included in the diagnostic criteria for arrthythmogenic right ventricular dysplasia (ARVD) based on the Revised Task Force criteria 2010. The epsilon wave, which reflects delayed conduction of the right ventricle, is considered to be one of the major diagnostic criteria. We reported a 13-year-old Thai boy with ...
Calkins Hugh - - 2013
Arrhythmogenic right ventricular dysplasia (ARVD) is an inherited cardiomyopathy and is also called ARVD/C. In most cases, ARVD is inherited in an autosomal-dominant pattern and clinically is characterized by ventricular arrhythmias with an increased risk of sudden death. Although it is prominently a disease of the right ventricle (RV), involvement ...
Ahmed Atif Ali - - 2013
We present an autopsy case of a male baby born at 35 weeks of gestation with pulmonary atresia with intact ventricular septum (PAIVS), who had coronary blood flow that was dependent on outflow from the right ventricle through the vessels described by Wearn. At 7 weeks of age, he underwent ...
Kashima Katsuro - - 2013
The subject was a 70 year-old man who survived for 31 years after being diagnosed with right ventricular cardiomyopathy, having undergone right ventricular (RV) aneurysmectomy at the age of 39. His arrhythmia and syncopal attacks were effectively abolished after the original aneurysmectomy. Although he frequently suffered from right heart failure, ...
GwizdaƂa Adrian - - 2013
Since arrhythmogenic right ventricular dysplasia is still an under-recognised clinical entity, its 'deceitful' course requires alertness of physicians, and - in particular - awareness of its less typical manifestations. Therefore, we present a case report of a 52-year-old male subject with signs and symptoms of right ventricular heart failure and ...
Le Trung Bao - - 2012
We study the formation of the mitral vortex ring during early diastolic filling in a patient-specific left ventricle using direct numerical simulation. The geometry of the left ventricle is reconstructed from Magnetic Resonance Imaging (MRI). The heart wall motion is modeled by a cell-based activation methodology, which yields physiologic kinematics ...
Saw Jacqueline - - 2012
Fibromuscular dysplasia (FMD) is a segmental non-atherosclerotic, non-inflammatory vasculopathy typically of small-medium muscular arteries. Coronary FMD (CFMD) is believed to be rare. However, we have found an association between spontaneous coronary artery dissection (SCAD) and FMD as the cause of myocardial infarction in ∼25% of young women age <50. It ...
Matsuno Yukihiro - - 2012
We describe a case of a 64-year-old man with constrictive pericarditis of unusual anatomy. Preoperative investigations revealed the thickened and calcified pericardial ring encircling the right and left ventricular cavity at the level of the atrioventricular (AV) groove and crossing the left anterior descending coronary artery, leading to strangulation of ...
Igarashi Takashi - - 2012
A 31-year-old male was diagnosed with congestive heart failure due to left ventricular noncompaction and coarctation of the aorta by echocardiography and computed tomography. He also developed mitral valve prolapse of the posteromedial commissural leaflet due to rupture of chordae tendineae. Segmental leaflet resection was performed with ring annuloplasty. Aorto-bifemoral ...
Aggarwal Gunjan - - 2012
Ischaemic mitral regurgitation after myocardial infarction results from geometric changes in left ventricular shape and displacement of papillary muscles with resultant tethering and incomplete leaflet coaptation of mitral leaflets. Post mitral valve repair, both valve apparatus related factors such as persistent leaflet tethering and progressive left ventricular adverse remodelling and ...
Hung Judy J Cardiac Ultrasound Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. - - 2012
Ischemic mitral regurgitation (IMR) often persists, despite annular ring reduction. It has been hypothesized that persistent IMR following ring annuloplasty was related to a continued tethering of the mitral leaflets, as defined by the distance by which the papillary muscles (PMs) were displaced outside the mitral annular ring. Seven sheep ...
Langer Frank - - 2012
OBJECTIVE: The MiCardia DYANA annuloplasty system (MiCardia Corp, Irvine, Calif) is a nitinol-based dynamic complete ring that allows modification of the septal-lateral diameter under transesophageal echocardiography guidance in the loaded beating heart after mitral valve repair. Shape alteration is induced by radiofrequency via detachable activation wires. This multicenter study reports ...
Lincoln Trent - - 2012
We report the unusual case of a 72-year-old woman with a primary presentation of right heart failure in the setting of recently diagnosed Ebstein's anomaly with concomitant atrial fibrillation (AF). The patient had New York Heart Association (NYHA) class III dyspnea for 12 months, with refractory right heart failure prior ...
Wong Vincent M - - 2012
Undersized mitral annuloplasty (MA) is the preferred surgical treatment for chronic ischemic mitral regurgitation. However, the preferred shape of undersized MA is unclear. A previously described finite element model of the left ventricle with mitral valve based on magnetic resonance images of a sheep with chronic ischemic mitral regurgitation after ...
Ohkubo Kimie - - 2012
The stepwise approach to radiofrequency (RF) ablation of atrial fibrillation (AF) can include ablation of the coronary sinus (CS) by RF delivery at the left atrium (LA) and/or within the CS. In both cases, the energy is applied between the tip electrode of a percutaneous catheter and a dispersive electrode ...
Kossaify Antoine - - 2012
An 80-year-old patient having a dual chamber DR pacer connected to a VDD lead presented with chronic lead dislodgment with the atrial ring displaced into the right ventricle. There was no ventricular capture at maximal ventricular output, and given the clinical settings, the condition was managed with a conservative approach, ...
Pagel Paul S - - 2011
OBJECTIVE: Transmitral blood flow during early left ventricular (LV) filling produces an intraventricular rotational body of fluid known as a "vortex ring" that enhances the hydraulic efficiency of early LV filling. The authors tested the hypothesis that exposure to cardiopulmonary bypass (CPB) attenuates intraventricular vortex formation time (VFT) in patients ...
Huizar Jose F - - 2012
Cardiac resynchronization therapy (CRT) demands high energy utilization due to continuous biventricular pacing. Current technology allows 6 pacing configurations for a bipolar left ventricular (LV) lead. Understanding the energy requirements for each configuration will allow optimization of pacing output. Pacing impedance, LV voltage threshold at 1.5 ms (rheobase) and 0.4 ...
Minamiguchi Hitoshi H Division of Cardiology, University of Occupational and Environmental Health, Kitakyushu, - - 2012
Although low atrial septal (LAS) pacing may prevent atrial tachyarrhythmias in selected patients, far-field R-wave (FFRW) sensing in this region seems more likely than in the right atrial appendage. We compared the clinical characteristics and prevalence of FFRW sensing in 31 recipients (mean age, 74 ± 10 years) of dual-chamber ...
Fujimoto Shinichiro - - 2012
Coronary computed tomographic angiography (CTA) is a promising noninvasive tool that allows the visualization of plaque morphology. Plaques characterized by positive remodeling, low attenuation, and napkin ring circular enhancement on contrast-enhanced coronary CTA have been regarded as rupture-prone vulnerable plaques, which account for about 60% of all vulnerable lesions and ...
Rosendal Christian - - 2011
BACKGROUND: The impact of mitral valve surgery on left ventricular outflow tract (LVOT) dimensions is unclear. Real-time three-dimensional transesophageal echocardiography permits excellent visualization of the LVOT and might improve standard two-dimensional measurements. In this study, LVOT area and shape were assessed before and after mitral valve surgery. METHODS: Thirty-five patients ...
Chen Jian - - 2011
AimsVentricular arrhythmias arising from the fibrous rings have been demonstrated, but knowledge about the aortomitral continuity (AMC) as a source of the arrhytmias is still limited.  The objective is to describe the characteristics of ventricular arrhythmias originating from the AMC in patients without structural heart disease.Methods and resultsTen patients with ...
Chen Jennifer - - 2011
A 59-year-old man had, over a period of 5 years, three different clinical scenarios which led to dynamic left ventricular outflow tract obstruction (LVOTO). Initially, this man who suffered from hypertrophic cardiomyopathy presented with asymmetric septal hypertrophy and systolic anterior motion (SAM) of the anterior mitral leaflet, along with mitral ...
Light Edward D ED Department of Biomedical Engineering Duke University Durham, NC 27708, USA. - - 2011
As a treatment for aortic stenosis, several companies have recently introduced prosthetic heart valves designed to be deployed through a catheter using an intravenous or transapical approach. This procedure can either take the place of open heart surgery with some ofthe devices or delay it with others. Real-time 3D ultrasound ...
Nishio Mayu - - 2011
Background Disrupted plaques are the major cause of acute coronary syndrome (ACS). Although the detection of vulnerable plaques by coronary CT (CCT) has been examined and reported, there has been no report on the detection of disrupted plaques by CCT. Objectives To test the ability of CCT to detect disrupted ...
Soleimani Behzad - - 2011
During implantation of the HeartMate II left ventricular assist device, the inflow cannula is typically inserted in such a way that the sewing ring is placed within the ventricular cavity in contact with the endocardium. We describe a novel implantation technique in which the sewing ring is secured to the ...
Kim Hye-Seon - - 2011
We report a case of pseudo-pseudoaneurysm, which is a very rare complication of myocardial infarction. A 69-year-old man was admitted to our clinic with chest tightness and dyspnea. He had undergone aortic valve replacement with a pericardial bioprosthetic valve, ring mitral annuloplasty, and reconstruction of an aortic annular defect due ...
Myers P - - 2011
Evidence is mounting that mitral valve repair can improve symptoms in adults with dilated cardiomyopathy. Data is currently lacking for children with dilated cardiomyopathy and options for annuloplasty are limited in children. We report on the successful management of a 21 month-old child in heart failure from dilated cardiomyopathy and ...
Refaat Marwan - - 2011
A paced right bundle-branch block (RBBB) QRS morphology is present in most patients with biventricular pacing (BiVP) but is also present in some patients with right ventricular pacing (RVP). The aim of this study was to determine if there are electrocardiographic characteristics that distinguish BiVP from RVP in patients with ...
Harding Melissa E - - 2011
Dual site left ventricular pacing through two left ventricular pacing leads, located in discrete vessels, significantly lowered pacing thresholds from 6 V at 1 ms and 4.25 V at 0.5 ms through the leads individually, to 0.75 V at 0.5 ms by utilizing a Y-adaptor to connect the two leads.
Hara Masahiko - - 2011
Background: Chronic effect of right ventricular (RV) pacing on left ventricular (LV) rotational synchrony is unknown. The aim of this study is to assess chronic effect of RV pacing on LV rotational synchrony using two-dimensional ultrasound speckle tracking imaging. Methods and Results: Thirty-one patients who underwent dual-chamber pacemaker implantation for ...
Scharf Christoph - - 2011
For successful cardiac resynchronisation therapy (CRT) a spatial and electrical separation of right and left ventricular electrodes is essential. The spatial distribution of electrical delays within the coronary sinus (CS) tributaries has not yet been identified. Electrical delays within the CS are described during sinus rhythm (SR) and right ventricular ...
Patterson Cam C Division of Cardiology and McAllister Heart Institute, University of North Carolina at Chapel Hill, 8200 Medical Biomolecular Research Building, Chapel Hill, NC 27599-7126, USA. - - 2011
Cardiac hypertrophy develops in response to increases in afterload, most commonly as the result of hypertension. When left untreated, cardiac hypertrophy commonly progresses to heart failure, one of the leading causes of death in the US. A number of studies have shown that reversing cardiac hypertrophy can decrease the progression ...
Kapa Suraj - - 2010
While for decades right ventricular (RV) apical pacing has been the standard of care for patients requiring pacemaker or defibrillator lead placement, investigators have sought alternatives to achieve more physiologic electrical activation of the heart and reduce long-term pathologic effects of nonphysiologic apical pacing. These investigations have included attempts at ...
Oosterhoff Peter - - 2010
high-rate pacing may have an inhibitory effect on the initiation of Torsade de Pointes arrhythmias (TdP). However, permanent pacing is only indicated in high-risk patients. We performed a proof of concept study into automatic overdrive pacing for prevention of drug-induced TdP, using short-term variability of repolarization (STV) as a feedback ...
Zanon Francesco - - 2011
Introduction:  In the right ventricle, selective site pacing (SSP) has been shown to avoid detrimental hemodynamic effects induced by right ventricular apical pacing and, in the right atrium, to prevent the onset of atrial fibrillation and to slow down disease progression. The purpose of our multicenter observational study was to ...
Ji Ling - - 2010
Velocity vector imaging (VVI) allows noninvasive measurement of left ventricular (LV) strain and rotation angle-independently. We investigated strain, rotation and myocardial synchrony when pacing at different sites in the right ventricle to determine which site yields the most physiological pacing, as determined with VVI imaging. Thirty-one patients with normal LV ...
Qiao Qing - - 2010
BACKGROUND: Paced QRS duration, a good marker of ventricular asynchrony while pacing, has been accepted as a valuable predictor of new-onset heart failure in patients receiving right ventricular apical pacing. But nowadays we have little evidence for predicting paced QRS duration before the implantation. HYPOTHESIS: There might be relationships between ...
Qiao Qing - - 2010
Paced QRS duration, a good marker of ventricular asynchrony while pacing, has been accepted as a valuable predictor of new-onset heart failure in patients receiving right ventricular apical pacing. But nowadays we have little evidence for predicting paced QRS duration before the implantation. There might be relationships between paced QRS ...
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