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Uhm Jae-Sun JS Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Clinical significance of first-degree atrioventricular block (AVB) have not been known in patients with hypertension. This study was performed to elucidate long-term prognosis of first-degree AVB in patients with hypertension. We included 3816 patients (mean age, 61.0 ± 10.6 years; men, 47.2%) with hypertension. We reviewed their ECGs and measured the PR ...
Tabara Yasuharu Y aCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto bDepartment of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, - - 2014
Increasing blood pressure (BP) variability is reported to be a cardiovascular risk factor. However, the clinical implications of postprandial hypotension (PHYPO), a commonly observed BP variability in elderly persons, are poorly understood. Here, we investigated the possible associations between postprandial BP decline and asymptomatic cerebral damage in community residents. Study ...
Brouwer Emily S ES From the aDepartment of Pharmacy Practice and Science, Institute for Pharmaceutical Outcomes and Policy, University of Kentucky, Lexington, KY; bDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC; cDepartment of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC; and dDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, - - 2014
Cohort studies have demonstrated greater risk of myocardial infarction (MI) associated with specific antiretroviral use, while meta-analyses of randomized controlled trials (RCTs) have not. These differences may be due to inherent biases in the observational study design or to the limited duration of randomized trials. We conducted a new-user, active-comparator ...
Gao Xiao-Jin XJ Department of Cardiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167th Beilishilu Rd, Xicheng District, Beijing, 100037, - - 2014
The prevalence of myocardial perfusion and glucose metabolic abnormalities and their significance in patients with isolated left ventricular non-compaction (ILVNC) have not been well investigated. Seventeen ILVNC patients who underwent cardiac magnetic resonance (CMR) and (99m)Tc-sestamibi SPECT/fluorine-18 deoxyglucose ((18)F-FDG) PET imaging were included. Left ventricular non-compaction, regional wall motion abnormalities, ...
Lakkireddy Dhanunjaya D KU Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital, Kansas City, - - 2014
Cocaine use is a known but rare cause of cardiac arrhythmias. Ventricular arrhythmias related to cocaine may not respond to antiarrhythmic drugs and may need treatment with radiofrequency ablation. We describe the clinical and electrophysiological characteristics of cocaine- related ventricular tachycardia (VT) from a multicenter registry. Subjects presenting with VT ...
van de Hoef Tim P TP AMC Heartcentre, Academic Medical Centre, University of Amsterdam, , Amsterdam, The - - 2014
Fractional flow reserve (FFR) aims to identify the extent of epicardial disease, but may be obscured by involvement of the coronary microvasculature. We documented the impact of hyperaemic stenosis resistance (HSR) and hyperaemic microvascular resistance (HMR) on FFR, and its relationship with myocardial ischaemia in patients with stable coronary artery ...
McCormick Liam M LM Department of Cardiology, Papworth Hospital, - - 2014
Randomised trials have shown that direct stenting (DS) is associated with improved markers of reperfusion during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI). However, data evaluating its impact on long-term clinical outcomes are lacking. We set out to evaluate the effect of DS on mortality in ...
Callisaya Michele L ML Department of Medicine, Southern Clinical School, Monash Medical Centre, Monash University, Melbourne, Australia; Menzies Research Institute, University of Tasmania, Hobart, - - 2014
White matter hyperintensities increase the risk of multiple falls in older people, but the effect of sub-cortical infarcts is unknown. By pooling data from two Australian population-based studies, we aimed to investigate the association between sub-cortical infarcts and multiple falls and whether this relationship, and that of white matter hyperintensities, ...
Nishikura Tenjin T The Department of Medicine, Division of Cardiology, Showa University School of - - 2014
Aim: The aim of the present study was to investigate how small dense low-density lipoprotein cholesterol (sdLDL-C) compared with LDL-C affect the long-term prognosis in patients with stable coronary artery disease (CAD). Methods: sdLDL-C measured by heparin magnesium precipitation and LDL particle size measured by non-denatured gradient-gel electrophoresis were compared ...
Trifunovic Danijela - - 2014
Insulin resistance (IR) assessed by the Homeostatic Model Assessment (HOMA) index in the acute phase of myocardial infarction in non-diabetic patients was recently established as an independent predictor of intrahospital mortality. In this study we postulated that acute IR is a dynamic phenomenon associated with the development of myocardial and ...
Hou Jia J Division of Paediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who had undergone TOF repair ...
Adlbrecht C - - 2014
Endothelin (ET)-1 is a pro-fibrotic vasoconstrictive peptide causing microvascular dysfunction and cardiac remodelling after acute ST-elevation myocardial infarction (STEMI). It acts via two distinct receptors, ET-A and ET-B, and is involved in inflammation and atherogenesis. Patients with posterior-wall STEMI were randomly assigned to intravenous BQ-123 at 400 nmol/minute (min) or ...
Taoka T T From the Department of Radiology (T.T., M.S., T.M., T.A., T.O., S.H., K.K.) and Critical Care Medicine (M.F.), Nara Medical University, Nara, Japan; Siemens Japan KK (M.U.), Tokyo Japan; and Siemens Medical Solutions USA (J.X.), New York, New - - 2014
Diffusion kurtosis is a statistical measure for quantifying the deviation of the water diffusion profile from a Gaussian distribution. The current study evaluated the time course of diffusion kurtosis in patients with cerebral infarctions, including perforator, white matter, cortical, and watershed infarctions. Subjects were 31 patients, representing 52 observations of ...
Roswell Robert O RO Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New - - 2014
The 2013 American College of Cardiology Foundation/American Heart Association ST-segment elevation myocardial infarction (STEMI) guidelines have shifted focus from door-to-balloon (D2B) time to the time from first medical contact to device activation (contact-to-device time [C2D] ). This study investigates the impact of prehospital wireless electrocardiogram transmission (PHT) on reperfusion times to ...
Frommeyer Gerrit G Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, - - 2014
The most recent European Society of Cardiology (ESC) update on atrial fibrillation has introduced vernakalant (VER) for pharmacological cardioversion of atrial fibrillation. The aim of the present study was to investigate the safety profile of VER in a sensitive model of proarrhythmia.METHODS AND RESULTS: In 36 Langendorff-perfused rabbit hearts, VER ...
Rivera Santiago S Division of Cardiology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, - - 2014
Pseudo ischemic ST segment changes during supraventricular tachycardia (SVT) are not yet fully understood. Our aim was to determine whether venticulo-atrial (VA) conduction during SVT may be a possible mechanism for ST depression (STd) in SVT. Patients undergoing SVT ablation (2010-2012) were analyzed (n = 72).Typical atrioventricular node reentrant tachycardia ...
Maskhulia L L Clinical Centra of Sports Medicine and Rehabilitation of Tbilisi State Medical University, Tbilisi, - - 2014
Athlete's heart should be differentiated from the hypertrophic cardiomyopathy (HCM)-leading cause of exercise related sudden cardiac death in young athletes. Some genetic variations of HCM are characterized by a benign clinical course and a delayed onset of the disease. Therefore, substantial increase of left ventricular wall thickness (LVWT) in adolescent ...
Shimizu Atsuya A Department of Cardiology, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Cardiology, Nagoya University, Nagoya, - - 2014
Cerebral white matter lesions (WML) are known to increase with age, as is left ventricular (LV) diastolic dysfunction with normal contraction. Although aging is a common risk factor, the link between these diseases is not fully understood. The aim was to clarify this relationship, using the ratio between early diastolic ...
Velders M A MA Department of Cardiology, Medical Center Leeuwarden, PO Box 888, 8901 BR, Leeuwarden, the Netherlands, - - 2014
Everolimus-eluting stents (EES) were superior to sirolimus-eluting stents (SES) in a dedicated myocardial infarction trial, a finding that was not observed in trials with low percentages of ST-elevation myocardial infarction (STEMI). Therefore, this study sought to investigate the influence of clinical presentation on outcome after EES and SES implantation. A ...
Vural Murat M Department of Radiology, Ankara Numune Education and Research Hospital, Talatpasa Bulvarı, Sıhhiye, Ankara, Turkey, - - 2014
The aim of the present study was to evaluate the relationship between epicardial fat tissue (EFT) volume and left ventricular diastolic function. A total of 63 patients (29 male, 34 female, mean age 57.8 ± 10.9 years) were enrolled in the study. Multidetector computed tomography (MDCT) and 2D transthoracic echocardiography were performed in ...
Borde Laura L Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Boulevard de Colonster 20, B41, 4000, Liège, - - 2014
To assess the prognostic value of echocardiographic parameters of left ventricular (LV) function in horses with systemic inflammatory response syndrome (SIRS). Prospective observational study. Veterinary teaching hospital. Forty-one horses admitted for colic with clinical evidence of SIRS. All horses underwent Doppler echocardiographic examination on admission. LV echocardiographic parameters, including pulsed-wave ...
Hughes William S WS Medicine, Georgetown University, 3800 Resevoir Road NW, Washington, District of Columbia, 20037, - - 2014
Studies of autopsies of military members dying in three US wars indicate that the prevalence of atherosclerosis in successive cohorts of healthy young men and women has dramatically decreased over the past half century. The objective of this study was to compare the decline in the prevalence of atherosclerosis and ...
Zhang Qi Q Department of Cardiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Sirolimus-eluting stents (SES) with a biodegradable polymer coating have demonstrated promising results but have not been compared to SES with a durable polymer in high-risk patients. We compared the efficacy of these 2 stent types in patients with acute myocardial infarction (STEMI). One thousand one hundred ninety-two STEMI patients were ...
Romano Edson Renato ER Unidade de Terapia Intensiva, Hospital do Coração, São Paulo, SP, - - 2014
Background: Available predictive models for acute coronary syndromes (ACS) have limitations as they have been elaborated some years ago or limitations with applicability. Objectives: To develop scores for predicting adverse events in 30 days and 6 months in ST-segment elevation and non-ST-segment elevation ACS patients admitted to private tertiary hospital. ...
Choi Woong Gil WG Division of Cardiology, Department of Internal Medicine, Konkuk University College of Medicine, Chungju, - - 2014
Functional mitral regurgitation (FMR) and myocardial dyssynchrony commonly occur in patients with dilated cardiomyopathy (DCM). The aim of this study was to elucidate changes in FMR in relation to those in left ventricular (LV) dyssynchrony as well as geometric parameters of the mitral valve (MV) in DCM patients during dobutamine ...
Mohammed Selma F SF Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Mayo Graduate School, Mayo Clinic, Rochester, - - 2014
This study sought to determine the frequency of left ventricular amyloid in heart failure with preserved ejection fraction (HFpEF). Left ventricular amyloid deposition can cause diastolic dysfunction and HFpEF. Autopsy of left ventricular specimens from patients with antemortem diagnosis of HFpEF without clinically apparent amyloid (n = 109) and from control ...
Devereaux P J PJ The authors' affiliations are listed in the - - 2014
Background Marked activation of the sympathetic nervous system occurs during and after noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and death without inducing hemodynamic instability. Methods We performed a blinded, randomized trial with a 2-by-2 factorial design to allow separate evaluation of low-dose ...
Shimokawahara Hiroto H Institute for Clinical Research and Division of Cardiology, National Hospital Organization Kagoshima Medical Center, Kagoshima, - - 2014
Although vascular endothelial growth factor (VEGF) is elevated in patients with acute myocardial infarction (AMI), the clinical significance of its elevation remains unclear. The present study was designed to determine the relationship between VEGF and left ventricular dimension in patients with AMI. Plasma VEGF levels were examined by enzyme-linked immunosorbent ...
Kali Avinash A 1Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA; Department of Bioengineering, University of California, Los Angeles, CA; Department of Radiology, Northwestern University, Chicago, - - 2014
-LGE CMR is a powerful method for characterizing MI, but the requisite gadolinium infusion is estimated to be contraindicated in nearly 20% of MI patients due to end-stage chronic kidney disease. The purpose of this study is to investigate whether T1 Cardiovascular-Magnetic-Resonance Imaging (CMR) obtained without contrast agents at 3T ...
Ricci Renato Pietro RP Department of Cardiology, San Filippo Neri Hospital, , Rome, - - 2014
Inappropriate implantable cardioverter defibrillators (ICD) therapies have been associated with multiple adverse effects, including worse quality of life and prognosis. We evaluated the possibility of predicting atrial fibrillation (AF)-related inappropriate ICD shocks through continuous monitoring of device diagnostics. 1404 ICD patients were prospectively followed in an observational research by 74 ...
Demidova Marina M MM Department of Cardiology, Lund University, Lund, Sweden; Federal Centre of Heart, Blood and Endocrinology, St. Petersburg, Russia. Electronic address: - - 2014
Certain types of the early repolarization (ER) phenomenon, previously considered to be benign, have been reported to be associated with ventricular fibrillation (VF), both in population-based studies and in the myocardial infarction (MI) settings. Our aim was to analyse whether QRS widening and appearance of J-wave-pattern in experimental MI settings ...
Inagawa Tetsuji T Department of Neurosurgery, Shimane Prefectural Central - - 2014
We studied the risk factors associated with cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH). The subjects were 370 patients with ruptured aneurysms who fulfilled all of the following criteria: admission by day 2 after onset, operation performed by day 3 by the same surgeon (T.I.), Hunt-Hess grade I-IV, availability of ...
Boles Usama - - 2014
Abstract Objective: To assess the relationship between hematological inflammatory signs, cardiovascular risk (CV) factors and prognosis in patients presenting with acute myocardial infarction (AMI) and coronary artery ectasia (CAE). Design: We investigated 3321 AMI patients who required urgent primary percutaneous intervention, in two centres in the United Kingdom between January ...
Chen Ming-Ren MR Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Junior College of Medicine Nursing and Management, Taipei, Taiwan; Mackay Medical College, Taipei, - - 2014
Myocardial iron overload leading to congestive heart failure (HF) or arrhythmias is a recognized complication in thalassemia patients undergoing chronic blood transfusion. The relationship between myocardial iron load, subclinical systolic dysfunction, and clinical events remains less well known. We studied a total of 77 subjects, comprising 37 thalassemia patients (mean ...
Ayça Burak B Bağcılar Education and Research Hospital. - - 2014
Syntax score (SxS) is demonstrated to predict long-term outcomes in stable patients with coronary artery disease. But, its prognostic value for patients with acute coronary syndrome remains unknown. Therefore, in this study we aimed to evaluate whether SxS could predict in-hospital outcomes for patients admitted with ST elevation myocardial infarction ...
Demyanets Svitlana S Department of Internal Medicine II, Medical University of Vienna, Währinger-Gürtel 18-20, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, Währinger-Gürtel 18-20, 1090 Vienna, Austria. Electronic address: - - 2014
The study aim was to determine the predictive value of interleukin (IL)-33, a recently described member of the IL-1 family of cytokines, for the development of in-stent restenosis (ISR). IL-33 serum levels were measured in 387 consecutive patients undergoing percutaneous coronary intervention (PCI) of whom 193 had stable angina, 93 ...
Tigen Kursat K Department of Cardiology, Marmara University Faculty of Medicine, Istanbul, - - 2014
Severe mitral stenosis (MS) may impair left atrial (LA) pump function, and increase LA and pulmonary venous pressure resulting in right ventricular (RV) systolic dysfunction. The aim of this study was to evaluate biventricular and LA function after percutaneous mitral balloon valvuloplasty (PMBV) by tissue Doppler (TDI) and speckle tracking echocardiography ...
Calvert Patrick A PA University Hospitals Birmingham NHS Foundation Trust, Birmingham; University of Cambridge, Cambridge; Papworth Hospital NHS Foundation Trust, Cambridge, United - - 2014
Post-infarction ventricular septal defect (PIVSD) carries a grim prognosis. Surgical repair offers reasonable outcomes in patients who survive a healing phase. Percutaneous device implantation represents a potentially attractive early alternative. PIVSD closure was attempted in 53 patients from 11 centers (1997-2012) (age 72±11 years; 42% female). 19% had previous surgical ...
Patel Akshay J AJ Department of Cardiac Surgery, St. George's Hospital, London, - - 2014
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, 'What is the optimal revascularization technique for isolated disease of the left anterior descending artery (LAD) in terms of patient survival, morbidity such as myocardial infarction (MI) and need for repeat target ...
Zanon Francesco F 1Arrhythmia & EP Unit, Cardiology Department, Santa Maria Della Misericordia Hospital, Rovigo, - - 2014
-One of the reasons for patient non-response to cardiac resynchronization therapy (CRT) is a suboptimal left ventricular (LV) pacing site. LV electrical delay (Q-LV interval) has been indicated as a prognostic parameter of CRT response. This study evaluates the LV delay for optimization of the LV pacing site. -Thirty-two consecutive ...
Yingchoncharoen Teerapat T Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
Increased left ventricular (LV) dimensions are an indication for surgery in patients with asymptomatic mitral regurgitation, but M-mode or two-dimensional measurements have known limitations. The aim of this study was to determine the value of three-dimensional echocardiography in predicting postoperative outcomes after mitral surgery. Sixty-seven patients with severe asymptomatic or ...
Cortigiani Lauro L Cardiology Division, Campo di Marte Hospital, Lucca, - - 2014
The prognostic value of Doppler-derived coronary flow velocity reserve (CFVR) of the left anterior descending coronary artery in patients with type 2 diabetes with preserved left ventricular systolic function and without flow-limiting stenoses on angiography remains undetermined. The study sample consisted of 144 patients with type 2 diabetes (82 men; ...
Gupta Sunil S Heart Failure and Transplant Unit, St. Vincent's Hospital, Sydney, New South Wales, Australia; Faculty of Medicine, The University of New South Wales, Sydney, New South Wales, - - 2014
It is important to accurately monitor residual cardiac function in patients under long-term continuous-flow left ventricular assist device (cfLVAD) support. Two new measures of left ventricular (LV) chamber contractility in the cfLVAD-unloaded ventricle include IQ , a regression coefficient between maximum flow acceleration and flow pulsatility at different pump speeds; ...
Khoo Vanessa V aDepartment of Cardiology, National University Heart Centre bBiostatistics Unit, National University Health System cDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, - - 2014
We aimed to address the conflict over whether the underlying lesion that leads to acute myocardial infarction (AMI) is representative of low-grade or high-grade stenosis. Because the development of collateral vessels is an indication of ischemia, their presence was used as a surrogate marker for the existence of a high-grade ...
Chaikovsky Illya I aClinic of Cardiology, Main Military Clinical Hospital bDepartment of Chronic Coronary Artery Disease, National Cardiology Center 'N.D. Strazesko' cDepartment of Sensor Devises, Glushkov Institute of Cybernetics NASU, Main Military Clinical Hospital, Kiev, Ukraine dClinic of Cardiology, Catholic Hospitals Essen, University Witten Herdecke, Essen, - - 2014
The aim of this paper is to investigate the predictive value of the new integrated magnetocardiographic (MCG) index (CI) in the diagnosis of coronary artery disease (CAD) in patients with suspected CAD with intermediate pretest probability of the disease and uninformative results of routine tests. The study was carried out ...
Ichida Masaru M Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan. Electronic address: - - 2014
Some patients with hypertrophic cardiomyopathy (HCM) develop left ventricular apical aneurysm, leading to serious cardiovascular complications. The aims of this study were to identify the incidence and clinical course of HCM patients with apical aneurysms in Japan, and to evaluate the role of electrocardiography (ECG) as a screening test to ...
Ybarra Juan J aOverweight and Obesity Unit bDr Ballesta's Laparoscopic Surgical Center, Centro Médico Teknon, Barcelona, Spain cCleveland Clinic Foundation, Medina Hospital, Medina, Ohio, - - 2014
Alanine aminotransferase (ALT) is a marker of nonalcoholic fatty liver disease (NAFLD) and predicts type 2 diabetes mellitus (DM2) as well as coronary events independently of traditional risk factors and the features of the metabolic syndrome. The extent to which interventricular septum thickness (IVS) and left ventricular mass (LVM) are ...
Danchin Nicolas N Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris; INSERM U 970, Paris; Université Paris Descartes, Paris, - - 2014
Although primary percutaneous coronary intervention (pPCI) is the preferred reperfusion method for ST-elevation myocardial infarction (STEMI), it remains difficult to implement in many areas, and fibrinolytic therapy is still widely used. We assessed 5-year mortality in STEMI patients from the French registry of Acute ST-elevation or non-ST elevation Myocardial Infarction ...
Afridi Hassan Imran HI National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan, - - 2014
It has been speculated that trace elements may a play role in the pathogenesis of heart diseases. In the present study, we aimed to assess the levels of selenium (Se) and mercury (Hg) in biological samples (whole blood, urine, and scalp hair) of myocardial infarction (MI) patients of both genders ...
Glassy Matthew S MS Department of Internal Medicine, University of California, Irvine, 2141 Engineering Hall, Irvine, CA, 92697, - - 2014
Contrast enhanced echocardiography (CEE) is a technique for the improvement of suboptimal echocardiographic studies. While commonly performed at selected institutions, its value has only been shown qualitatively, and to this point no study has been directed at establishing a quantitative improvement in image quality compared with non-contrast enhanced echocardiography (non-CEE). ...
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