Search Results
Results 401 - 450 of 3844
< 4 5 6 7 8 9 10 11 12 13 14 >
Nolte Froukje F Department of Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, The - - 2014
Aims: It has been argued that hyperaemic microvascular resistance (HMR), defined as the ratio of mean distal coronary pressure to flow velocity, is overestimated in the presence of a coronary stenosis compared to actual microvascular resistance (MR), due to neglecting collateral flow. We aimed to test the hypothesis that HMR ...
Saito Shigeru S Division of Cardiology, Shonan Kamakura General - - 2014
Background: Prasugrel is an antiplatelet agent that shows more prompt, potent, and consistent platelet inhibition than clopidogrel. The objective of this study was to confirm the efficacy and safety of prasugrel at loading/maintenance doses of 20/3.75mg. Methods and Results: Japanese patients (n=1,363) with acute coronary syndrome undergoing percutaneous coronary intervention were randomized ...
Stamboul Karim K Cardiology Department, University Hospital, Dijon, - - 2014
Silent atrial fibrillation (AF) has been suggested to be frequent after acute myocardial infarction (MI). Continuous ECG monitoring (CEM) has been shown to improve AF screening in patients at risk of stroke. We aimed to assess the incidence and prognosis of silent AF in patients with acute MI. All the ...
Liu Xinbing - - 2014
Objective: To compare the therapeutic warfarin and aspirin efficacies for treatments of atrial fibrillation (AF) complicated with stable coronary heart disease particularly in older Chinese patients. Methods: In our prospective study 101 patients with AF and stable coronary heart disease older than 80 years were randomized into two groups. One ...
Kukla Piotr P Department of Cardiology, Specialistic Hospital, Gorlice, - - 2014
A 72-year-old man with heart failure, left ventricular dysfunction (ejection fraction 20%), prior ischemic stroke, COPD, and exacerbation of chronic renal failure was admitted in our unit. Serum potassium was 6.1 mmol/L, calcium concentration was at the lower normal range 2.15 mmol/L, and NT-pro-BNP was 28,900 pg/mL. The surface 12-lead ...
Neven Kars K Dept. of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; Dept. of Rhythmology, Alfried Krupp Krankenhaus, Essen, Germany. Electronic address: - - 2014
Electroporation can be used as a non-thermal method to ablate myocardial tissue. However, like with all electrical ablation methods, determination of the energy supplied into the myocardium enhances the clinically required controllability over lesion creation. The purpose of this animal study was to investigate the relationship between magnitude of epicardial ...
Wieringa Wouter G WG Thoraxcenter, Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen , The Netherlands - - 2014
In patients with ST-segment elevation myocardial infarction (STEMI), the time of onset of ischemia has been associated with myocardial infarction (MI) size. Myocardial blush grade (MBG) reflects myocardial response to ischemia/reperfusion injury, which may differ according to time of the day. The aim of our study was to explore the ...
Puymirat Etienne E aAssistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou, Department of Cardiology, Paris, Université Paris-Descartes bINSERM U-970 cAP-HP, Hôpital Saint Antoine, Department of Clinical Pharmacology and Unité de Recherche Clinique (URCEST) dUniversité Pierre et Marie Curie (UPMC-Paris 06) eAP-HP, Hôpital Bichat fParis, France, Université Paris-Diderot, Sorbonne Paris-Cité gINSERM U-698, Paris hUniversity Hospital Jean Minjoz, Department of Cardiology, Besançon iUniversity Hospital of Lille, Department of Cardiology, Lille jUniversity hospital of Nantes, Nantes kUniversity hospital of Nancy, Nancy lToulouse Rangueil University Hospital, Department of Cardiology, UMR1027, INSERM, Toulouse, - - 2014
A shorter time delay between onset of symptoms and first call for medical attention would be expected in patients with a history of ischemic heart disease (IHD). We aimed to determine whether time to first call for an ST-elevation myocardial infarction (STEMI) differed between patients with or without history of ...
Tonelli Marcello M Department of Medicine, University of Alberta, Edmonton, Canada; Department of Public Health Sciences, University of Alberta, Edmonton, Canada. Electronic address: - - 2014
Elucidation of the relationship between age, kidney function, and absolute coronary risk would facilitate efforts to promote chronic kidney disease (CKD) as a high-risk state for future vascular events and justify current recommendations for statin treatment in CKD. Population-based study. 1,268,538 people with data for estimated glomerular filtration rate and ...
Reeves Ryan R RR Department of Medicine, Division of Cardiovascular Medicine, University of California, San - - 2014
Objectives: To characterize the prevalence of thrombus burden, collateral vessels to the infarct-related artery, epicardial coronary artery flow, and myocardial perfusion in patients with angiographically confirmed definite stent thrombosis (ST), and to define their relationship with associated treatments and outcomes. Background: Angiographic characteristics of ST are not well defined. Methods: ...
Moore Jeremy P JP Division of Pediatric Cardiology, UCLA Medical Center. Electronic address: - - 2014
Tachycardia-induced cardiomyopathy (TIC) carries significant risk of morbidity and mortality, although full recovery is possible. Little is known about the myocardial recovery pattern. To determine the time course and predictors of myocardial recovery in pediatric TIC. An international multicenter study of pediatric TIC was conducted. Children ≤18 years with incessant ...
Brisco Meredith A MA Department of Medicine, Cardiovascular Division, Medical University of South Carolina, Charleston, South - - 2014
Although atrial arrhythmias (AAs) are common in heart failure, the incidence of AAs subsequent to the placement of left ventricular assist devices (LVADs) has not been elucidated. Patients receiving a HeartMate II LVAD in the bridge to transplant (n = 490) and destination therapy (n = 634) trials were included (n = 1125). AAs requiring treatment ...
Randall D A DA Centre for Health Research, School of Medicine, Blg 3 Campbelltown Campus, University of Western Sydney, Locked Bag 1797, Penrith, NSW 2751, Australia. Electronic address: - - 2014
We investigated disparities in rates of acute myocardial infarction (AMI) between Aboriginal and non-Aboriginal people in the 199 Statistical Local Areas (SLAs) in New South Wales, Australia. Using routinely collected and linked hospital and mortality data from 2002 to 2007, we developed multilevel Poisson regression models to estimate the relative ...
Hirai Taishi T Department of Medicine, Loyola University Chicago, Stritch School of Medicine, Loyola University Medical Center, Maywood, - - 2014
It is unknown whether recurrence of atrial fibrillation (AF) is related to severity of left ventricular diastolic dysfunction (LVDD) before ablation in patients with preserved left ventricular ejection fraction (LVEF). We tested the hypothesis that the presence and/or severity of LVDD before catheter ablation are related to AF recurrence during ...
Seth Ashok A Chairman - Cardiovascular Sciences & Chief Cardiologist, Fortis Escorts Heart Institute, Okhla Road, New Delhi 110025, India. Electronic address: - - 2014
Cardiovascular disease in Asia has reached epidemic proportions in recent years. Use of drug eluting stents in Asians has rapidly expanded with varying penetration rates across different countries. The XIENCE V(®) INDIA Study included 'real world' patients who underwent XIENCE V(®) stent implantation to assess short and intermediate term outcomes ...
Hara Masahiko M Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, - - 2014
Few studies have investigated whether angiotensin II receptor blocker (ARB) is a practical alternative to angiotensin-converting enzyme inhibitor (ACEI) for long-term use after acute myocardial infarction (AMI) in real-world practice in the percutaneous coronary intervention era. We compared 5-year survival benefits of ACEI and ARB in patients with AMI registered ...
Krepp Joseph M JM Greenberg Division of - - 2014
Left ventricular (LV) diastolic dysfunction (DD) is a known predictor of poor cardiovascular outcomes. Although ECG LV hypertrophy (LVH) is strongly associated with LV systolic dysfunction and heart failure, the relation of LV DD to ECG LVH is unclear. ECG LVH by Cornell product (CP) criteria was examined in a ...
Lambert Lauri J LJ Institut National d'Excellence en Santé et en Services Sociaux (INESSS), Montreal, Quebec, - - 2014
Inter-hospital transfer of patients with ST-elevation myocardial infarction (STEMI) for primary percutaneous coronary intervention (PPCI) is associated with longer delays to reperfusion, related partly to turnaround ('door-in' to 'door-out', DIDO) time at the initial hospital. As part of a systematic, province-wide evaluation of STEMI care, we examined DIDO times and ...
Cavalcante João L JL Heart and Vascular Institute, University of Pittsburgh-UPMC, Pittsburgh, - - 2014
Cardiac magnetic resonance (CMR) identifies important prognostic variables in ischemic cardiomyopathy (ICM) patients such as left ventricular (LV) volumes, LV ejection fraction (LVEF), peri-infarct zone, and myocardial scar burden (MSB). It is unknown whether Doppler-based diastolic dysfunction (DDF) retains its prognostic value in ICM patients, in the context of current ...
Lamberts Morton M Department of Cardiology, Gentofte University Hospital, Hellerup, Copenhagen, Denmark. Electronic address: - - 2014
To investigate the impact of atrial fibrillation (AF) and antithrombotic treatment on prognosis in patients with heart failure (HF) as well as vascular disease. HF, vascular disease and AF are pathophysiological related and understanding antithrombotic treatment in these conditions is crucial. In hospitalized patients with HF and co-existing vascular disease ...
Sanders Robert A RA Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, - - 2014
To determine if the transesophageal atrial (A) wave amplitude or ventricular (V) wave amplitude can be used to guide optimal positioning of a transesophageal pacing catheter in dogs. Prospective clinical study. Fourteen client owned healthy dogs with a median weight of 15.4 kg (IQR = 10.6-22.4) and a median age of 12 months (IQR = 6-12). ...
Barone Raffaella R aStudy of Coronary Blood Flow Unit bInterventional Cardiology, Az. Ospedaliera San Camillo Forlanini, Rome, - - 2014
Stress-induced ischemia may cause a decrease in left ventricular ejection fraction (EF). We evaluated the variation in early postexercise EF (S-EF) compared with rest EF (R-EF) in different clinical settings to detect ventricular dysfunction. We also correlated ventricular dysfunction with an angiographic score, the Syntax score, in a subgroup of ...
Yalonetsky Sergey S Department of Cardiology, Rambam Medical Center, Haifa, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, - - 2014
Right ventricular (RV) infarction is associated with increased mortality. Functional mitral regurgitation (FMR) may complicate inferoposterior infarction with RV involvement leading to pulmonary hypertension and increased RV afterload, potentially exacerbating RV remodeling and dysfunction. We studied 179 patients with inferior wall left ventricular (LV) ST-elevation myocardial infarction and RV infarction. ...
Arnold Suzanne V SV Saint Luke's Mid America Heart Institute, Kansas City, MO, - - 2014
While patients with diabetes mellitus (DM) have more extensive coronary disease and worse survival after acute myocardial infarction (AMI) than patients without DM, data on whether they experience more angina are conflicting. We examined angina prevalence over the year following AMI among 3367 patients, including 1080 (32%) with DM, from ...
Angel Arenal A A Hospital General Universitario Gregorio Marañón, Madrid, - - 2014
Endo-epicardial substrate ablation reduces ventricular tachycardia (VT) recurrences, however not all patients in whom the epicardium is explored have VT substrate. Contrast-enhanced magnetic resonance imaging (ceMRI) is used to characterize VT substrate after myocardial infarction. To determine if epicardial VT substrate can be identified noninvasively by ceMRI based endo-epicardial signal ...
Renzi Cristina C 1Department of Epidemiology, Regional Health Service, Lazio Region, Rome, - - 2014
/st>To evaluate whether public reporting of performance data was associated with a change over time in quality indicators for acute myocardial infarction (AMI) in Italian hospitals. /st>Pre-post evaluation of AMI indicators in the Lazio region, before and after disclosure of the Regional Outcome Evaluation Program, and a comparative evaluation versus ...
Wijnbergen Inge I aDepartment of Cardiology, Catharina Hospital Eindhoven bDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven cAcademic Medical Center, University of Amsterdam, Amsterdam, the - - 2014
We aimed to investigate, in patients with ST-segment elevation myocardial infarction (STEMI), whether the previously reported clinical benefits of sirolimus-eluting stent(s) (SES) in terms of reducing a major adverse cardiac and cerebrovascular event (MACCE) compared with bare-metal stent(s) (BMS) were maintained over a 5-year time period. In the prospective single-centre ...
Quinn Tom T Faculty of Health and Medical Sciences, University of Surrey, , Guildford, - - 2014
To describe patterns of prehospital ECG (PHECG) use and determine its association with processes and outcomes of care in patients with ST-elevation myocardial infarction (STEMI) and non-STEMI. Population-based linked cohort study of a national myocardial infarction registry. 288 990 patients were admitted to hospitals via emergency medical services (EMS) between ...
Yoshino Satoshi S aDepartment of Cardiovascular Medicine and Hypertension, Kagoshima University Hospital, Sakuragaoka, Kagoshima, Japan bDepartment of Internal Medicine, Division of Cardiovascular Diseases cDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics dDepartment of Experimental Pathology and Laboratory Medicine, Division of Genomics Shared Resource eDepartment of Internal Medicine, Division of Nephrology, Mayo Clinic and College of Medicine, Rochester, Minnesota, USA fDepartment of Cardiology, Ajou University Medical Center, Suwon, - - 2014
Single nucleotide polymorphisms (SNPs) are the most common source of genetic variation. Although microvascular pathology is associated with cardiovascular events, genetic phenotypes causing microvascular disease remain largely unknown. This study identifies sex-specific SNPs associated with coronary microvascular dysfunction. Six hundred and forty-three patients without significant obstructive coronary heart disease were ...
Krummen David E DE University of California San Diego, San Diego, CA; Veterans Affairs San Diego Healthcare System, San Diego, CA. Electronic address: - - 2014
We mapped human ventricular fibrillation (VF) to define mechanistic differences between episodes requiring defibrillation versus those that spontaneously terminate. VF is a leading cause of mortality, yet episodes may also self-terminate. We hypothesized that the initial maintenance of human VF is dependent upon the formation and stability of VF rotors. ...
Taglieri Nevio N Istituto di Cardiologia, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Alma Mater Studiorum Università di Bologna, - - 2014
To evaluate the relationship between ECG patterns and infarct related artery (IRA) in an all-comer population with ST-segment elevation myocardial infarction (STEMI) and validate current criteria for identifying IRA (right coronary artery (RCA) versus left circumflex artery (LCA)) in inferior STEMI and for diagnosing left main (LM) or left anterior ...
Moens Didier D aEmergency Department bHelicopter Emergency Medical Service - Centre Médical Héliporté de Bra-Sur-Lienne, Liège University Hospital cDepartment of Medical Informatics and Biostatistics dDepartment of Public Health, University of Liege, Liège, - - 2014
Primary prehospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We designed a prospective study involving patients with acute myocardial infarction aimed at the evaluation of the potential benefit of such primary HEMS interventions as compared ...
Loo Germaine G Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, - - 2014
We aimed to determine the prognostic implications of obstructive sleep apnea (OSA) diagnosed during the recovery phase of acute coronary syndrome (ACS). Patients presenting with ACS and treated with percutaneous coronary intervention were recruited prospectively for a home-based sleep study within 30days of hospital discharge. Major adverse cardiac and cerebrovascular ...
Karius Philipp P Department of Radiology, Charite Medical School, Humboldt-Universität zu Berlin, Freie Universität Berlin, Chariteplatz 1, 10117 Berlin, - - 2014
Coronary computed tomography angiography (CCTA) is of growing importance in noninvasive diagnosis of coronary artery diseases. The CT data allow evaluation not only of coronary arteries but also of adjacent anatomical territories. Our objective was to review, to analyze, and to quantify the spectrum and the prevalence of extracardiac findings ...
Guo Donglin D Lankenau Institute for Medical Research, Wynnewood, PA; College of Life Science, South-Central University for Nationalities, Wuhan, China. Electronic address: - - 2014
The late sodium current (INa-L) contributes importantly to rate-dependent change in action potential duration (APD) and transmural dispersion of repolarization (TDR). However, little is known about the mechanisms of increased APD rate-dependence and amplified TDR in left ventricular hypertrophy (LVH) and failure. The purpose of this study was to investigate ...
Faludi Réka R Faculty of Medicine, Heart Institute, University of Pécs, Pécs, Hungary. Electronic address: - - 2014
In systemic sclerosis (SSc), left ventricular diastolic dysfunction reflects primary myocardial involvement of the disease. We aimed to assess the abnormalities of the diastolic function, analyze the characteristics of the disease progression, and investigate the prognostic value of diastolic dysfunction in SSc patients. A total of 34 SSc patients (57 ...
Kotsia Anna A VA North Texas Healthcare System and UT Southwestern Medical Center, Dallas, - - 2014
Extensive coronary artery disease (CAD) is associated with higher risk. In this substudy of the PLATO trial, we examined the effects of randomized treatment on outcome events and safety in relation to the extent of CAD. Patients were classified according to presence of extensive CAD (defined as 3-vessel disease, left ...
Maiolino Giuseppe G aDepartment of Medicine - DIMED - Internal Medicine 4 bDivisione di Cardiologia, Ospedale di Cittadella, Cittadella cDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, - - 2014
We tested the hypothesis that variations in the PLA2G7 gene encoding the lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme deemed to have proatherogenic activity, affect the Lp-PLA2 levels and predicts cardiovascular events. Using a prospective cohort study design, we investigated incident cardiovascular events as a function of the PLA2G7 gene for ...
van de Hoef Tim P TP AMC Heartcentre, Academic Medical Centre, University of Amsterdam, , Amsterdam, The - - 2014
Fractional flow reserve (FFR) aims to identify the extent of epicardial disease, but may be obscured by involvement of the coronary microvasculature. We documented the impact of hyperaemic stenosis resistance (HSR) and hyperaemic microvascular resistance (HMR) on FFR, and its relationship with myocardial ischaemia in patients with stable coronary artery ...
Gao Xiao-Jin XJ Department of Cardiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167th Beilishilu Rd, Xicheng District, Beijing, 100037, - - 2014
The prevalence of myocardial perfusion and glucose metabolic abnormalities and their significance in patients with isolated left ventricular non-compaction (ILVNC) have not been well investigated. Seventeen ILVNC patients who underwent cardiac magnetic resonance (CMR) and (99m)Tc-sestamibi SPECT/fluorine-18 deoxyglucose ((18)F-FDG) PET imaging were included. Left ventricular non-compaction, regional wall motion abnormalities, ...
McCormick Liam M LM Department of Cardiology, Papworth Hospital, - - 2014
Randomised trials have shown that direct stenting (DS) is associated with improved markers of reperfusion during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI). However, data evaluating its impact on long-term clinical outcomes are lacking. We set out to evaluate the effect of DS on mortality in ...
Nishikura Tenjin T The Department of Medicine, Division of Cardiology, Showa University School of - - 2014
Aim: The aim of the present study was to investigate how small dense low-density lipoprotein cholesterol (sdLDL-C) compared with LDL-C affect the long-term prognosis in patients with stable coronary artery disease (CAD). Methods: sdLDL-C measured by heparin magnesium precipitation and LDL particle size measured by non-denatured gradient-gel electrophoresis were compared ...
Callisaya Michele L ML Department of Medicine, Southern Clinical School, Monash Medical Centre, Monash University, Melbourne, Australia; Menzies Research Institute, University of Tasmania, Hobart, - - 2014
White matter hyperintensities increase the risk of multiple falls in older people, but the effect of sub-cortical infarcts is unknown. By pooling data from two Australian population-based studies, we aimed to investigate the association between sub-cortical infarcts and multiple falls and whether this relationship, and that of white matter hyperintensities, ...
Inci Sinan S Department of Cardiology, Faculty of Medicine, Atatürk University; Erzurum-Turkey. - - 2014
The aim of this study was to prospectively evaluate the effect of percutaneous coronary intervention in the acute period on left ventricular dyssynchrony in ST-segment elevation myocardial infarction patients by using Tissue Synchronization Imaging. Forty-four ST-segment elevation myocardial infarction (MI) patients (29 male, 15 female), who were admitted within the ...
Kenaan Mohamad M Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, - - 2014
Earlier studies suggest that administering statins prior to percutaneous coronary interventions (PCIs) is associated with lower risk of periprocedural myocardial infarction and contrast-induced nephropathy. Current American College of Cardiology/American Heart Association guidelines recommend routine use of statins prior to PCI. It is unclear how commonly this recommendation is followed in ...
Trifunovic Danijela - - 2014
Insulin resistance (IR) assessed by the Homeostatic Model Assessment (HOMA) index in the acute phase of myocardial infarction in non-diabetic patients was recently established as an independent predictor of intrahospital mortality. In this study we postulated that acute IR is a dynamic phenomenon associated with the development of myocardial and ...
Mumma Bryn E BE Department of Emergency Medicine, University of California Davis, Sacramento, CA. Electronic address: - - 2014
Current guidelines recommend ≤90 minutes from first medical contact to percutaneous coronary intervention (FMC2B) for ST-segment-elevation myocardial infarction (STEMI) patients. We evaluated the relationship between patient home distance from a percutaneous coronary intervention (PCI) center, prehospital electrocardiogram (ECG) use, and FMC2B time among patients with STEMI. We performed a retrospective ...
Hou Jia J Division of Paediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who had undergone TOF repair ...
Wimmer Neil J NJ Brigham and Women's Hospital, Harvard Medical School, Boston, - - 2014
Randomized clinical trials (RCTs) suggest benefits for the transradial approach to percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). However, transradial PCI may delay reperfusion, leading to its avoidance. We sought to quantify the delay in reperfusion from transradial PCI ("transradial delay") that would need to be introduced to ...
Lolaty Hamideh Azimi HA Department of Psychiatric Nursing, School of Nursing & Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address: - - 2014
To investigate the effect of family-friend visits on anxiety, physiological indices and well-being of patients with acute myocardial infarction. A checklist was used to gather socio-demographic data and physiologic indices including blood pressure, heart rate, respiratory rate, and arterial oxygen saturation. The short-form of the Spielberger state anxiety inventory, a ...
< 4 5 6 7 8 9 10 11 12 13 14 >