Search Results
Results 401 - 450 of 3215
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Imanishi Junichi - - 2013
Postoperative atrial fibrillation (POAF) is associated with increased risk of embolic events and heart failure, but its associated factors remains unknown. Left atrial (LA) subclinical mechanical dysfunction caused by the acute stress of surgery may be clinically manifested as POAF. The purpose of our study was therefore to test the ...
Biering-Sørensen Tor - - 2013
Doppler tissue imaging (DTI) detects early signs of left ventricular (LV) dysfunction; however, the prognostic significance of DTI after ST-segment elevation myocardial infarction (STEMI) is unknown. The aim of this study was to evaluate the prognostic value of DTI after STEMI in patients treated with primary percutaneous coronary intervention. In ...
Di Serafino Luigi - - 2013
Monocyte-platelet aggregates (MPA) are increased in patients with acute coronary syndrome. We investigated whether MPA are associated with the presence of functionally significant coronary stenoses or with coronary arterial endothelial dysfunction. One hundred forty five patients undergoing elective coronary angiography were prospectively enrolled. Functional significance of coronary stenosis was assessed ...
Alipour Fariborz - - 2013
Supraglottic compression is frequently observed in individuals with dysphonia. It is commonly interpreted as an indication of excessive circumlaryngeal muscular tension and ventricular medialization. The purpose of this study was to describe the aerodynamic and acoustic impact of varying ventricular medialization in a canine model. Subglottal air pressure, glottal airflow, ...
Moukarbel George V GV Division of Cardiovascular Medicine, Department of Internal Medicine, University of Toledo Medical Center, 3000 Arlington Avenue, Toledo, OH 43614, - - 2013
Renal dysfunction is associated with poor cardiovascular outcome. We investigated the relationship of kidney function and long-term cardiovascular outcomes in patients with high risk myocardial infarction. We studied 27 610 patients from four randomized trials of acute myocardial infarction complicated by heart failure and/or LV dysfunction (LVEF ≤40%). Two trials excluded ...
Reiter Ursula U From the Department of Radiology, Medical University of Graz, Auenbruggerplatz 9/P, A-8036 Graz, Austria (U.R., R.M., M.F.); Siemens, Healthcare Sector, Graz, Austria (G.R.); Department of Radiology, Feldbach Regional Hospital, Feldbach, Austria (K.D.); and Siemens, Healthcare Sector, Erlangen, Germany - - 2013
Purpose To introduce blood normalization for myocardial T1 values at magnetic resonance (MR) imaging and to evaluate regional differences between systolic and diastolic myocardial T1 values in healthy subjects. Materials and Methods This prospective study (ClinicalTrials.gov identification number, NCT01728597) was approved by the institutional review board, and volunteer informed consent ...
Morino Yoshihiro - - 2013
Clopidogrel in combination with aspirin has been a standard therapy for patients who have undergone percutaneous coronary intervention. The present study was conducted as a postmarketing surveillance, for the purpose of assessing the safety and efficacy of clopidogrel in real clinical practice in patients with non-ST-segment-elevation acute coronary syndrome (NSTE-ACS). ...
Meier Pascal - - 2013
We sought to assess the prognostic role of collaterals in a large population of patients presenting with an acute coronary syndrome (ACS). The coronary collateral circulation was assessed by an independent angiographic core laboratory using the Rentrop Score in patients enrolled in the randomised Acute Catheterization and Urgent Intervention Triage ...
Cullen Louise - - 2013
Concentrations of troponin measured with high sensitivity troponin assays are raised in a number of emergency department (ED) patients; however many are not diagnosed with acute myocardial infarction (AMI). Clinical comparisons between the early use (2h after presentation) of high sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI) assays for ...
Gao Zhaohui - - 2013
Animal studies indicate that alpha-adrenergic coronary vasoconstriction helps maintain left ventricular function during physiological stress. Whether this process occurs in humans is unknown. In the current study, we used transthoracic Doppler echocardiography to test the effect of lower body negative pressure (LBNP) on coronary blood flow velocity (CBV, left anterior ...
Chawla Lakhmir S - - 2013
AKI is associated with major adverse kidney events (MAKE): death, new dialysis, and worsened renal function. CKD (arising from worsened renal function) is associated with a higher risk of major adverse cardiac events (MACE): myocardial infarction (MI), stroke, and heart failure. Therefore, the study hypothesis was that veterans who develop ...
Tiroch Klaus K Department of Cardiology, Helios Klinikum Wuppertal, Universität Witten/Herdecke, Wuppertal, Germany. Electronic address: - - 2013
This study sought to evaluate the impact of anatomic and procedural variables on the outcome of the unprotected left main coronary artery (uLMCA) itself after drug-eluting stent (DES) implantation. There is a controversial debate regarding when and how to perform percutaneous coronary intervention (PCI) for an uLMCA stenosis. This analysis ...
Sabaté Manel M University Hospital Clinic, IDIBAPS, Cardiology Department, Barcelona, Spain. Electronic address: - - 2013
This study sought to assess the 2-year outcomes of the population included in the EXAMINATION (Everolimus-Eluting Stents Versus Bare-Metal Stents in ST-Segment Elevation Myocardial Infarction) trial beyond the 1-year prescription period of dual antiplatelet therapy. The EXAMINATION trial compared the performance of everolimus-eluting stents (EES) versus bare-metal stents (BMS) in ...
Mocova Bilkova Dana D Charles University, Prague, Czech - - 2013
Subjective symptoms represent significant criteria of a patient's health condition; therefore, we focused on the long-term prevalence of heart failure symptoms and angina pectoris after myocardial infarction between two groups of patients in which two different therapeutic strategies were used during the acute phase of ST-elevation myocardial infarction (STEMI). The ...
Kmet Marko - - 2013
Glucometabolic status is an important predictor of prognosis in patients with acute myocardial infarction. Both plasma glucose levels and glycosylated hemoglobin A1c (HbA1c) were implicated as predictors of prognosis. However, previous data yielded conflicting results. We evaluated the prognostic role of plasma glucose levels and HbA1c in patients with non-ST ...
Verdoia Monica - - 2013
Periprocedural myocardial infarction (PMI) represents a frequent complication in patients undergoing percutaneous coronary revascularization. Despite great attention focused on pharmacological prevention of periprocedural damage, very little is known about using biomarkers to potentially predict the risk of PMI. Larger platelets have been associated with enhanced reactivity, increased cardiovascular risk, and ...
Umemura Toshitaka - - 2013
Albuminuria, a marker of chronic kidney disease, is associated with an increased risk of incident stroke and unfavorable long-term outcomes. However, the association of albuminuria with short-term outcomes and change in infarct volume in patients with acute small subcortical infarction remains unknown. We retrospectively reviewed 85 consecutive patients with acute ...
Celik Turgay - - 2013
Although mean platelet volume (MPV) is an independent correlate of impaired angiographic reperfusion and 6-month mortality in ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI), there is less data regarding the association between platelet distribution width (PDW) and in-hospital major adverse cardiovascular events (MACEs). A total ...
Schou Morten - - 2013
Renal dysfunction is associated with a variety of cardiac alterations including left ventricular (LV) hypertrophy, LV dilation, and reduction in systolic and diastolic function. It is common and associated with an increased mortality risk in heart failure (HF) patients. This study was designed to evaluate whether severe diastolic dysfunction contribute ...
Johnson Jonas J School for Technology and Health, Royal Institute of Technology, Stockholm, - - 2013
Tissue Doppler imaging (TDI) is a promising echocardiographic modality allowing quantification of myocardial performance. However, the prognostic potential of TDI in patients with acute myocardial infarction (AMI) is not yet investigated. We sought to explore the ability of TDI in identifying patients at risk for new cardiovascular events after AMI. ...
Jaguszewski Milosz - - 2013
Recently, it has been suggested that the type of stent used in primary percutaneous coronary interventions (pPCI) might impact on outcomes of patients with acute myocardial infarction (AMI). Indeed, drug-eluting stents (DES) reduce neointimal hyperplasia when compared to bare-metal stents (BMS); moreover the later generation DES due to its biocompatible ...
Stergiopoulos Kathleen - - 2013
IMPORTANCE Myocardial ischemia in patients with stable coronary artery disease (CAD) has been repeatedly associated with impaired survival. However, it is unclear if revascularization with percutaneous coronary intervention (PCI) to relieve ischemia improves outcomes compared with medical therapy (MT). OBJECTIVE The objective of this study was to compare the effect ...
Sipahi Ilke - - 2013
IMPORTANCE Recent trials of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) for multivessel disease were not designed to detect a difference in mortality and therefore were underpowered for this outcome. Consequently, the comparative effects of these 2 revascularization methods on long-term mortality are still unclear. In the ...
De Luca Giuseppe - - 2013
Hypertension is a well known risk factor for atherosclerosis. However, data on the impact of hypertension in patients with ST-segment elevation myocardial infarction (STEMI) are inconsistent, and mainly related to studies performed in the thrombolytic era, with very few data on patients undergoing primary angioplasty. The aim of the current ...
Bulhões Mendonça Kelminda Maria - - 2013
Coronary artery disease constitutes a public health issue involving high mortality rates. The objectives of this study were to evaluate the feelings and perception of patients hospitalized before myocardial revascularization and to explore doctor-patient interactions before cardiac surgery with special attention to existential challenges. A qualitative, exploratory study involving patients ...
Schwartz Roy - - 2013
Previous studies demonstrated the superiority of primary percutaneous coronary intervention (PCI) over thrombolysis for treatment of ST-elevation myocardial infarction (STEMI); however, this advantage is less evident in low-risk populations. The aim of this study was to assess whether a strategy of thrombolysis followed by routine coronary angiography in patients with ...
Pereira-da-Silva Tiago - - 2013
To evaluate the long-term clinical outcomes following percutaneous coronary intervention (PCI) with the Genous stent in an unselected population. All patients admitted to a single center who underwent PCI using the GS exclusively, between May 2006 and May 2012, were enrolled, and a clinical follow-up of up to 60 months ...
Qin Xiao-Juan XJ Department of Medical Ultrasound, Huazhong University of Science and Technology, Wuhan, 430022, China, - - 2013
The function of the transplanted heart will be affected by acute allograft rejection, chronic rejection, high blood pressure and so on, which may induce the reconstruction of the left ventricle and the increase of left ventricular mass (LVM), and eventually lead to left ventricular hypertrophy that will significantly affect the ...
Naganuma Toru T Department of Cardio-Thoracic and Vascular Diseases, San Raffaele Scientific Institute, Milan, - - 2013
The aim of this study was to compare, in a large all-comer registry, the long-term clinical outcomes after percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for ostial/mid-shaft lesions versus distal bifurcation lesions in unprotected left main coronary artery (ULMCA) stenosis. Limited data are available regarding clinical outcomes following DES ...
Athappan Ganesh G Department of Cardiovascular Medicine, Heart & Vascular Institute, Case Western Reserve University, Cleveland, - - 2013
The goal of this study was to provide a systematic review comparing the long-term outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass graft surgery (CABG) for unprotected left main coronary artery (UPLM) stenosis. One-year outcomes from randomized controlled trials, observational studies, and pooled analyses ...
Dharma Surya S Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, - - 2013
Real-world data on acute coronary syndrome (ACS) patients who received intra-aortic balloon pump (IABP) support are limited. The objective of this study was to evaluate the characteristics of ACS patients who received IABP support from a real-world ACS registry. Patients with ACS (N = 121) who received IABP support were enrolled. Characteristics ...
Banović Marko M Department of Cardiology, University Clinical Centre of Serbia, Belgrade, Serbia. - - 2013
Early detection of left ventricle (LV) systolic dysfunction could be a clue for surgical treatment in patients with significant aortic stenosis (AS). Therefore, we evaluated LV peak of global longitudinal strain (PGLS) using speckle tracking imaging at rest and during low-dose dobutamine infusion in asymptomatic patients with moderate and severe ...
Rigolli Marzia M Awhina Health Campus, Waitakere Hospital, Waitemata District Health Board, Private Bag 93-503, Auckland, New Zealand ; Division of Cardiology, University of Verona, Ospedale Maggiore, Ple Stefani 1, 37126 Verona, - - 2013
Progressive aging of the population and prolongation of life expectancy have led to the rising prevalence of heart failure (HF). Despite the improvements in medical therapy, the mortality rate of this condition has remained unacceptably high, becoming the primary cause of death in the elderly population. Almost half of patients ...
Falcão Felipe José de Andrade FJ Department of Cardiology, Universidade Federal de São Paulo, São PauloSP, - - 2013
To identify predictors of in-hospital mortality in patients with acute myocardial infarction undergoing pharmacoinvasive treatment. This was an observational, prospective study that included 398 patients admitted to a tertiary center for percutaneous coronary intervention within 3 to 24 hours after thrombolysis with tenecteplase. ClinicalTrials.gov: NCT01791764 RESULTS: The overall in-hospital mortality ...
Camuglia A C - - 2013
Time to reperfusion is among the strongest predictors of clinical outcome in patients who present with ST elevation acute myocardial infarction. When time to access is equivalent, primary percutaneous coronary intervention has demonstrated superior outcomes to fibrinolysis. However, where significant delays exist in accessing percutaneous intervention, fibrinolysis has an important ...
Dehghani Farnaz F Department of Nursing, Physiology Research Center, Kerman University of Medical Sciences, Kerman, - - 2013
Despite some evidences about protective or triggering role of opium use in patients with coronary artery disease, the exact role of opium is still under question. The current study aimed to address the relation of opium dependence on the severity and extension of myocardial infarction (MI) and its related mortality. ...
Koç Zehra Pınar - - 2013
Since twenty-four-hour imaging by Tl-201 myocardial perfusion scintigraphy has been introduced as an effective additional procedure, the aim of this study was to compare this method's result with only rest redistribution procedure in the diagnosis of myocardial viability. Thirty patients (Seven female, 23 male; mean: 59.8 ± 10.7, 55.8-63.8 years ...
Bhuyan Soumitra Sudip SS Dept. of Health Services Research & Administration, UNMC College of Public Health, 984350 Nebraska Medical Center, Omaha, NE 68198-4350, - - 2013
Acute myocardial infarction (AMI) remains a major cause of death and disability in the United States and worldwide. Despite the importance of surveillance and secondary prevention, the incidence of and mortality from AMI are not continuously monitored, and little is known about survival outcomes after 30 days of AMI hospitalization ...
Shacham Yacov - - 2013
An elevated C-reactive protein (CRP) level is associated with adverse outcomes in patients with acute myocardial infarction (AMI). Although CRP levels have been shown to be associated with left ventricular (LV) systolic function and remodeling in AMI, little is known about their relation to early LV diastolic function. We retrospectively ...
Liebetrau Christoph - - 2013
N-terminal segment of B-type natriuretic peptide prohormone (NT-proBNP) is elevated in patients with acute myocardial infarction (AMI) thus providing both diagnostic information and prognostic information. The aim of the present study was to determine the time course of NT-proBNP release in patients undergoing transcoronary ablation of septal hypertrophy (TASH) a ...
Niccoli Giampaolo - - 2013
Parvovirus (PV) B19 DNA is detected in endothelial cells and may cause endothelial dysfunction which is involved in in-stent restenosis. We aimed at performing an exploratory analysis that evaluated if PVB19 DNA at the culprit coronary stenosis would be associated with an increased rate of major adverse cardiac events (MACE) ...
Brown David A - - 2013
We recently showed that Bendavia, a novel mitochondria-targeting peptide, reduced infarction and no-reflow across several experimental models. The purpose of this study was to determine the therapeutic timing and mechanism of action that underlie Bendavia's cytoprotective property. In rabbits exposed to in vivo ischemia/reperfusion (30/180 min), Bendavia administered 20 minutes ...
Bortnick Anna E AE Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New - - 2013
Management of coronary artery disease (CAD) has evolved over the past decade, but there are few prospective studies evaluating long-term outcomes in a real-world setting of evolving technical approaches and secondary prevention. The aim of this study was to determine how the mortality and morbidity of CAD has changed in ...
Mu Lingmin L Morphological Laboratory, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. - - 2014
The aim of the present study was to examine the expression of N-cadherin in the myocardial tissues of isoproterenol-induced myocardial hypertrophy in rats. In addition, the present study provided morphological data to investigate the signal transduction mechanisms of myocardial hypertrophy and reverse myocardial hypertrophy. A myocardial hypertrophy model was established ...
Gravning Jørgen - - 2013
-The incremental prognostic value of high-sensitive troponin T (hs-cTnT) in heart failure (HF) beyond that of hs-CRP and NT-proBNP is debated. We examined the prognostic value of hs-cTnT in a subgroup of patients from the CORONA study (Controlled Rosuvastatin Multinational Trial in HF). -Hs-cTnT as a risk factor for the ...
Paparella Domenico - - 2013
Myocardial damage occurs after valve surgery, but its prognostic implication has not been evaluated. The aim of the present study was to assess the influence of myocardial damage on mortality and morbidity in patients undergoing aortic surgery (AVS) and mitral valve surgery (MVS). In a prospective multicenter study from the ...
Close Glenn R GR Western Sydney Local Health District, - - 2013
Socioeconomic disadvantage is associated with an increased risk of developing heart failure and with inferior health outcomes following diagnosis. Data for hospitalisations and deaths due to heart failure in the Sydney metropolitan region were extracted from New South Wales hospital records and Australian Bureau of Statistics databases for 1999-2003. Standardised ...
Witzenbichler Bernhard - - 2013
Prior small to modest sized studies suggest a benefit of IVUS guidance in non-complex lesions. Whether IVUS guidance is associated with improved clinical outcomes after drug-eluting stent (DES) implantation in an unrestricted patient population is unknown. ADAPT-DES was a prospective, multicenter, non-randomized "all-comers" study of 8583 consecutive patients at 11 ...
Zeymer U - - 2013
This prospective registry assessed the safety and efficacy of paclitaxel coated balloon (PCB) angioplasty for small vessel coronary artery disease in Europe and Asia with the intention to treat lesions without additional stenting. The use of PCBs in small vessels seems to be associated with favourable outcomes; however, prospective data ...
Philip Femi - - 2013
BACKGROUND: THE RELATIVE SAFETY OF DRUG-ELUTING STENTS (DESS) AND BARE-METAL STENTS (BMSS) WITH RESPECT TO STENT THROMBOSIS (ST) CONTINUES TO BE DEBATED. THERE ARE LIMITED DATA COMPARING SAFETY AND EFFICACY OF SECOND-GENERATION DES TO BMS. WE COMPARED THE CLINICAL OUTCOMES BETWEEN SECOND-GENERATION DES AND BMS FOR PRIMARY PERCUTANEOUS CORONARY INTERVENTION ...
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