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Results 351 - 400 of 3714
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Lakkireddy Dhanunjaya D KU Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital, Kansas City, - - 2014
Cocaine use is a known but rare cause of cardiac arrhythmias. Ventricular arrhythmias related to cocaine may not respond to antiarrhythmic drugs and may need treatment with radiofrequency ablation. We describe the clinical and electrophysiological characteristics of cocaine- related ventricular tachycardia (VT) from a multicenter registry. Subjects presenting with VT ...
van de Hoef Tim P TP AMC Heartcentre, Academic Medical Centre, University of Amsterdam, , Amsterdam, The - - 2014
Fractional flow reserve (FFR) aims to identify the extent of epicardial disease, but may be obscured by involvement of the coronary microvasculature. We documented the impact of hyperaemic stenosis resistance (HSR) and hyperaemic microvascular resistance (HMR) on FFR, and its relationship with myocardial ischaemia in patients with stable coronary artery ...
Maiolino Giuseppe G aDepartment of Medicine - DIMED - Internal Medicine 4 bDivisione di Cardiologia, Ospedale di Cittadella, Cittadella cDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, - - 2014
We tested the hypothesis that variations in the PLA2G7 gene encoding the lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme deemed to have proatherogenic activity, affect the Lp-PLA2 levels and predicts cardiovascular events. Using a prospective cohort study design, we investigated incident cardiovascular events as a function of the PLA2G7 gene for ...
McCormick Liam M LM Department of Cardiology, Papworth Hospital, - - 2014
Randomised trials have shown that direct stenting (DS) is associated with improved markers of reperfusion during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI). However, data evaluating its impact on long-term clinical outcomes are lacking. We set out to evaluate the effect of DS on mortality in ...
Callisaya Michele L ML Department of Medicine, Southern Clinical School, Monash Medical Centre, Monash University, Melbourne, Australia; Menzies Research Institute, University of Tasmania, Hobart, - - 2014
White matter hyperintensities increase the risk of multiple falls in older people, but the effect of sub-cortical infarcts is unknown. By pooling data from two Australian population-based studies, we aimed to investigate the association between sub-cortical infarcts and multiple falls and whether this relationship, and that of white matter hyperintensities, ...
Nishikura Tenjin T The Department of Medicine, Division of Cardiology, Showa University School of - - 2014
Aim: The aim of the present study was to investigate how small dense low-density lipoprotein cholesterol (sdLDL-C) compared with LDL-C affect the long-term prognosis in patients with stable coronary artery disease (CAD). Methods: sdLDL-C measured by heparin magnesium precipitation and LDL particle size measured by non-denatured gradient-gel electrophoresis were compared ...
Inci Sinan S Department of Cardiology, Faculty of Medicine, Atatürk University; Erzurum-Turkey. - - 2014
The aim of this study was to prospectively evaluate the effect of percutaneous coronary intervention in the acute period on left ventricular dyssynchrony in ST-segment elevation myocardial infarction patients by using Tissue Synchronization Imaging. Forty-four ST-segment elevation myocardial infarction (MI) patients (29 male, 15 female), who were admitted within the ...
Trifunovic Danijela - - 2014
Insulin resistance (IR) assessed by the Homeostatic Model Assessment (HOMA) index in the acute phase of myocardial infarction in non-diabetic patients was recently established as an independent predictor of intrahospital mortality. In this study we postulated that acute IR is a dynamic phenomenon associated with the development of myocardial and ...
Kenaan Mohamad M Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, - - 2014
Earlier studies suggest that administering statins prior to percutaneous coronary interventions (PCIs) is associated with lower risk of periprocedural myocardial infarction and contrast-induced nephropathy. Current American College of Cardiology/American Heart Association guidelines recommend routine use of statins prior to PCI. It is unclear how commonly this recommendation is followed in ...
Hou Jia J Division of Paediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who had undergone TOF repair ...
Mumma Bryn E BE Department of Emergency Medicine, University of California Davis, Sacramento, CA. Electronic address: - - 2014
Current guidelines recommend ≤90 minutes from first medical contact to percutaneous coronary intervention (FMC2B) for ST-segment-elevation myocardial infarction (STEMI) patients. We evaluated the relationship between patient home distance from a percutaneous coronary intervention (PCI) center, prehospital electrocardiogram (ECG) use, and FMC2B time among patients with STEMI. We performed a retrospective ...
Wimmer Neil J NJ Brigham and Women's Hospital, Harvard Medical School, Boston, - - 2014
Randomized clinical trials (RCTs) suggest benefits for the transradial approach to percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). However, transradial PCI may delay reperfusion, leading to its avoidance. We sought to quantify the delay in reperfusion from transradial PCI ("transradial delay") that would need to be introduced to ...
Adlbrecht C - - 2014
Endothelin (ET)-1 is a pro-fibrotic vasoconstrictive peptide causing microvascular dysfunction and cardiac remodelling after acute ST-elevation myocardial infarction (STEMI). It acts via two distinct receptors, ET-A and ET-B, and is involved in inflammation and atherogenesis. Patients with posterior-wall STEMI were randomly assigned to intravenous BQ-123 at 400 nmol/minute (min) or ...
Taoka T T From the Department of Radiology (T.T., M.S., T.M., T.A., T.O., S.H., K.K.) and Critical Care Medicine (M.F.), Nara Medical University, Nara, Japan; Siemens Japan KK (M.U.), Tokyo Japan; and Siemens Medical Solutions USA (J.X.), New York, New - - 2014
Diffusion kurtosis is a statistical measure for quantifying the deviation of the water diffusion profile from a Gaussian distribution. The current study evaluated the time course of diffusion kurtosis in patients with cerebral infarctions, including perforator, white matter, cortical, and watershed infarctions. Subjects were 31 patients, representing 52 observations of ...
Roswell Robert O RO Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New - - 2014
The 2013 American College of Cardiology Foundation/American Heart Association ST-segment elevation myocardial infarction (STEMI) guidelines have shifted focus from door-to-balloon (D2B) time to the time from first medical contact to device activation (contact-to-device time [C2D] ). This study investigates the impact of prehospital wireless electrocardiogram transmission (PHT) on reperfusion times to ...
Gür Mustafa M Adana Numune Training and Research Hospital, Department of Cardiology, Adana, Turkey. Electronic address: - - 2014
Reperfusion and ischemic injuries are pathogenetic mechanisms of no-reflow. Oxidative stress plays a critical role during ischemia as well as during the reperfusion phase following ST elevation myocardial infarction (STEMI). We sought to investigate the relationship between no-reflow with paraoxonase-1 (PON-1) activity and oxidative stress markers (total antioxidant capacity (TAC), ...
Shen Lan L Duke Clinical Research Institute, Durham, NC; Shanghai Renji Hospital, Department of Cardiology, Shanghai, - - 2014
Prior myocardial infarction (MI) is a known risk factor for long-term mortality among acute MI patients; but its prevalence and implications for the short-term outcomes of patients with a new, acute MI remain uncertain. We studied a total of 319,152 consecutively enrolled ST-segment elevation MI (STEMI) and non-STEMI (NSTEMI) patients ...
Frommeyer Gerrit G Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, - - 2014
The most recent European Society of Cardiology (ESC) update on atrial fibrillation has introduced vernakalant (VER) for pharmacological cardioversion of atrial fibrillation. The aim of the present study was to investigate the safety profile of VER in a sensitive model of proarrhythmia.METHODS AND RESULTS: In 36 Langendorff-perfused rabbit hearts, VER ...
Rivera Santiago S Division of Cardiology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, - - 2014
Pseudo ischemic ST segment changes during supraventricular tachycardia (SVT) are not yet fully understood. Our aim was to determine whether venticulo-atrial (VA) conduction during SVT may be a possible mechanism for ST depression (STd) in SVT. Patients undergoing SVT ablation (2010-2012) were analyzed (n = 72).Typical atrioventricular node reentrant tachycardia ...
Shimizu Atsuya A Department of Cardiology, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Cardiology, Nagoya University, Nagoya, - - 2014
Cerebral white matter lesions (WML) are known to increase with age, as is left ventricular (LV) diastolic dysfunction with normal contraction. Although aging is a common risk factor, the link between these diseases is not fully understood. The aim was to clarify this relationship, using the ratio between early diastolic ...
Velders M A MA Department of Cardiology, Medical Center Leeuwarden, PO Box 888, 8901 BR, Leeuwarden, the Netherlands, - - 2014
Everolimus-eluting stents (EES) were superior to sirolimus-eluting stents (SES) in a dedicated myocardial infarction trial, a finding that was not observed in trials with low percentages of ST-elevation myocardial infarction (STEMI). Therefore, this study sought to investigate the influence of clinical presentation on outcome after EES and SES implantation. A ...
Vural Murat M Department of Radiology, Ankara Numune Education and Research Hospital, Talatpasa Bulvarı, Sıhhiye, Ankara, Turkey, - - 2014
The aim of the present study was to evaluate the relationship between epicardial fat tissue (EFT) volume and left ventricular diastolic function. A total of 63 patients (29 male, 34 female, mean age 57.8 ± 10.9 years) were enrolled in the study. Multidetector computed tomography (MDCT) and 2D transthoracic echocardiography were performed in ...
Borde Laura L Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Boulevard de Colonster 20, B41, 4000, Liège, - - 2014
To assess the prognostic value of echocardiographic parameters of left ventricular (LV) function in horses with systemic inflammatory response syndrome (SIRS). Prospective observational study. Veterinary teaching hospital. Forty-one horses admitted for colic with clinical evidence of SIRS. All horses underwent Doppler echocardiographic examination on admission. LV echocardiographic parameters, including pulsed-wave ...
Hughes William S WS Medicine, Georgetown University, 3800 Resevoir Road NW, Washington, District of Columbia, 20037, - - 2014
Studies of autopsies of military members dying in three US wars indicate that the prevalence of atherosclerosis in successive cohorts of healthy young men and women has dramatically decreased over the past half century. The objective of this study was to compare the decline in the prevalence of atherosclerosis and ...
Zhang Qi Q Department of Cardiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Sirolimus-eluting stents (SES) with a biodegradable polymer coating have demonstrated promising results but have not been compared to SES with a durable polymer in high-risk patients. We compared the efficacy of these 2 stent types in patients with acute myocardial infarction (STEMI). One thousand one hundred ninety-two STEMI patients were ...
Mohammed Selma F SF Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Mayo Graduate School, Mayo Clinic, Rochester, - - 2014
This study sought to determine the frequency of left ventricular amyloid in heart failure with preserved ejection fraction (HFpEF). Left ventricular amyloid deposition can cause diastolic dysfunction and HFpEF. Autopsy of left ventricular specimens from patients with antemortem diagnosis of HFpEF without clinically apparent amyloid (n = 109) and from control ...
Lee Ki Hong KH 0000-0002-9938-3464 Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, - - 2014
We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n=270, 92.3±2.3 yr old) with octogenarian AMI patients (n=2,145, 83.5±2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, ...
Kim Jeong Hun JH 0000-0002-5637-1121 The Heart Center of Chonnam National University Hospital, Gwangju, Korea. ; Department of Public Health, Chonnam National University Medical School, Gwangju, - - 2014
The aim of this study was to evaluate whether the clinical outcomes were associated with socioeconomic status (SES) in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI). The author analyzed 2,358 patients (64.9 ± 12.3 yr old, 71.5% male) hospitalized with AMI between November 2005 and ...
Youn Jong-Chan JC 0000-0003-0998-503X Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, - - 2014
Heart failure (HF) complicating acute myocardial infarction (AMI) is common and is associated with poor clinical outcome. Limited data exist regarding the incidence and in-hospital mortality of AMI with HF (AMI-HF). We retrospectively analyzed 1,427 consecutive patients with AMI in the five major university hospitals in Korea at two time ...
Sarıkaya Savaş S Department of Cardiology, Bozok University and Cumhuriyet University Faculty of Medicine, Yozgat, Turkey. - - 2014
Objectives: Our aim was to determine whether there is a relationship between admission gamma-glutamyltransferase (GGT) and subsequent heart failure hospitalizations in patients with acute coronary syndrome. Study design: We selected 123 patients with newly diagnosed acute coronary syndrome of ejection fraction (EF) <45%. Patients were followed 15±10 months, and the ...
Liu Yongxing - - 2014
Coronary artery perforation (CAP) is a rare, serious complication of percutaneous coronary intervention (PCI). Many studies have addressed the incidence, risk factors, and management of CAP in different countries except China. The aim of this study is to determine the risk factors and types of treatment for coronary perforation occurring ...
Choi Woong Gil WG Division of Cardiology, Department of Internal Medicine, Konkuk University College of Medicine, Chungju, - - 2014
Functional mitral regurgitation (FMR) and myocardial dyssynchrony commonly occur in patients with dilated cardiomyopathy (DCM). The aim of this study was to elucidate changes in FMR in relation to those in left ventricular (LV) dyssynchrony as well as geometric parameters of the mitral valve (MV) in DCM patients during dobutamine ...
Shacham Yacov Y Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: - - 2014
Previous data reported worse outcomes in female patients after acute ST elevation myocardial infarction (STEMI), related at least in part to less aggressive and nonparallel treatment. We investigated the presence of gender differences in left ventricular (LV) systolic and diastolic function in patients presenting with first STEMI, treated with primary ...
Conrotto Federico F Department of Cardiology, Città della Salute e della Scienza Hospital, Turin, Italy. Electronic address: - - 2014
Percutaneous coronary intervention (PCI) with drug-eluting stents is an accepted alternative to surgery for the treatment of unprotected left main coronary artery (ULMCA) disease, but the long-term outcome in elderly patients is unclear. Aim of our study was to compare the clinical outcomes of octogenarians with ULMCA disease treated either ...
De Abreu Maximiliano M Grupo de Estudio, Docencia e Investigación Clínica, Investigadores del Registro Epi-Cardio, Buenos Aires, Argentina. Electronic address: - - 2014
Observational studies have reported a marked discrepancy between the risk estimated by scores and the use of an invasive strategy in patients with acute coronary syndromes. The objective is to describe the criteria used to decide an early invasive strategy and to determine the differences between those criteria and the ...
Alqarawi Wael A WA Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, Toronto, Canada; University of Toronto, Toronto, - - 2014
Although the adverse prognosis of Q-waves on electrocardiogram (ECG) has been demonstrated, the prognostic significance of prominent R wave (PRW) in V1 or V2 across a broad spectrum of acute coronary syndrome (ACS) has not been specifically studied. In the Global Registry of Acute Coronary Events (GRACE) and the Canadian ...
Romano Edson Renato ER Unidade de Terapia Intensiva, Hospital do Coração, São Paulo, SP, - - 2014
Background: Available predictive models for acute coronary syndromes (ACS) have limitations as they have been elaborated some years ago or limitations with applicability. Objectives: To develop scores for predicting adverse events in 30 days and 6 months in ST-segment elevation and non-ST-segment elevation ACS patients admitted to private tertiary hospital. ...
Matoshvili Z Z Central University Clinic after N. Kipshidze, Tbilisi; Tbilisi State Medical University, Department of Internal Medicine №1, - - 2014
Early repolarization pattern is a common ECG pattern characterized by J-point and ST segment elevation in 2 or more contiguous leads. There are some opinions that early repolarization may be associated with some kind of arrhythmias (including life-threatening arrhythmias) Aim of this study was to declare correlation between early repolarization ...
Muzaffar Tasneem T Department of Cardiovascular and Thoracic Surgery, Soura, Kashmir, - - 2014
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly which represents one of the most common causes of myocardial ischemia and infarction in children. This anomaly, if left untreated, results in a very high mortality rate within the first year of life. ...
Arso Irsad A IA Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta, - - 2014
Aim: to compare the in-hospital major cardiovascular events between thrombolysis therapy and primary percutaneous coronary intervention (PCI) in patients with ST-elevation acute myocardial infarction (STEMI. Methods: the study design is retrospective cohort. Medical record of patients with STEMI onset <12 hour receiving thrombolysis treatment or primary PCI in Dr. Sardjito ...
Shimokawahara Hiroto H Institute for Clinical Research and Division of Cardiology, National Hospital Organization Kagoshima Medical Center, Kagoshima, - - 2014
Although vascular endothelial growth factor (VEGF) is elevated in patients with acute myocardial infarction (AMI), the clinical significance of its elevation remains unclear. The present study was designed to determine the relationship between VEGF and left ventricular dimension in patients with AMI. Plasma VEGF levels were examined by enzyme-linked immunosorbent ...
Devereaux P J PJ The authors' affiliations are listed in the - - 2014
Marked activation of the sympathetic nervous system occurs during and after noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and death without inducing hemodynamic instability. We performed a blinded, randomized trial with a 2-by-2 factorial design to allow separate evaluation of low-dose clonidine versus ...
Ter Haar C Cato CC Cardiology Department, Leiden University Medical Center, Leiden, The - - 2014
The ECG is important in diagnosis and triage in the initial phase of the acute coronary syndrome (ACS). The primary goal of making an ECG at first medical contact should be the reliable detection of cardiac ischemia, thus facilitating a correct triage by corroborating the diagnosis of ACS. Ischemia detection ...
Kali Avinash A 1Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA; Department of Bioengineering, University of California, Los Angeles, CA; Department of Radiology, Northwestern University, Chicago, - - 2014
-LGE CMR is a powerful method for characterizing MI, but the requisite gadolinium infusion is estimated to be contraindicated in nearly 20% of MI patients due to end-stage chronic kidney disease. The purpose of this study is to investigate whether T1 Cardiovascular-Magnetic-Resonance Imaging (CMR) obtained without contrast agents at 3T ...
Ricci Renato Pietro RP Department of Cardiology, San Filippo Neri Hospital, , Rome, - - 2014
Inappropriate implantable cardioverter defibrillators (ICD) therapies have been associated with multiple adverse effects, including worse quality of life and prognosis. We evaluated the possibility of predicting atrial fibrillation (AF)-related inappropriate ICD shocks through continuous monitoring of device diagnostics. 1404 ICD patients were prospectively followed in an observational research by 74 ...
Demidova Marina M MM Department of Cardiology, Lund University, Lund, Sweden; Federal Centre of Heart, Blood and Endocrinology, St. Petersburg, Russia. Electronic address: - - 2014
Certain types of the early repolarization (ER) phenomenon, previously considered to be benign, have been reported to be associated with ventricular fibrillation (VF), both in population-based studies and in the myocardial infarction (MI) settings. Our aim was to analyse whether QRS widening and appearance of J-wave-pattern in experimental MI settings ...
Inagawa Tetsuji T Department of Neurosurgery, Shimane Prefectural Central - - 2014
We studied the risk factors associated with cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH). The subjects were 370 patients with ruptured aneurysms who fulfilled all of the following criteria: admission by day 2 after onset, operation performed by day 3 by the same surgeon (T.I.), Hunt-Hess grade I-IV, availability of ...
Boles Usama - - 2014
Abstract Objective: To assess the relationship between hematological inflammatory signs, cardiovascular risk (CV) factors and prognosis in patients presenting with acute myocardial infarction (AMI) and coronary artery ectasia (CAE). Design: We investigated 3321 AMI patients who required urgent primary percutaneous intervention, in two centres in the United Kingdom between January ...
Chen Ming-Ren MR Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Junior College of Medicine Nursing and Management, Taipei, Taiwan; Mackay Medical College, Taipei, - - 2014
Myocardial iron overload leading to congestive heart failure (HF) or arrhythmias is a recognized complication in thalassemia patients undergoing chronic blood transfusion. The relationship between myocardial iron load, subclinical systolic dysfunction, and clinical events remains less well known. We studied a total of 77 subjects, comprising 37 thalassemia patients (mean ...
Ayça Burak B Bağcılar Education and Research Hospital. - - 2014
Syntax score (SxS) is demonstrated to predict long-term outcomes in stable patients with coronary artery disease. But, its prognostic value for patients with acute coronary syndrome remains unknown. Therefore, in this study we aimed to evaluate whether SxS could predict in-hospital outcomes for patients admitted with ST elevation myocardial infarction ...
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