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Legner D D Centre for Research in Computational and Applied Mechanics, University of Cape Town, Cape Town, South Africa; Computational Continuum Mechanics Group, Department of Civil Engineering, University of Cape Town, Cape Town, South - - 2013
Myocardial infarction is an increasing health problem worldwide. Because of an under-supply of blood, the cardiomyocytes in the affected region permanently lose their ability to contract. This in turn gradually weakens the overall heart function. A new therapeutic approach based on the injection of a gel into the infarcted area ...
López-Pérez Manuel M Cardiology Department, Complejo Hospitalario Universitario A Coruña, A Coruña, - - 2013
The presence of mitral regurgitation (MR) is associated with an impaired prognosis in patients with ischemic heart disease. However, data with regard to the impact of this condition in patients with ST-segment elevation myocardial infarction (STEMI) treated by means of primary percutaneous coronary intervention (PPCI) are lacking. Our aim was ...
Esposito Roberta R Echocardiography Laboratory, Department of Translational, Medical Sciences Federico II University, Naples, - - 2013
To investigate determinants of right ventricular (RV) function in competitive athletes by a combined assessment of speckle tracking (STE) and real time 3D echocardiography (RT3DE). Right ventricular function of 40 top-level rowers was compared to 43 sedentary normal controls by standard Doppler echocardiography, RT3DE, and STE. RV diameters and wall ...
Lee Ji-Hyun JH Department of Anesthesiology and Pain medicine, Seoul National University Hospital, Seoul, - - 2013
This study evaluated the prolongation of QT interval by the combination of sevoflurane and ondansetron in pediatric patients. Additionally, transmural dispersion of repolarization as interval between the peak and end of the T wave (Tp-e) and Tp-e/QT ratio was also measured to assess the risk of ventricular arrhythmia. The 3-lead ...
Burke Michael A MA 1Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, - - 2013
-Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome associated with multiple pathophysiologic abnormalities, including left ventricular (LV) diastolic dysfunction, longitudinal LV systolic dysfunction, abnormal ventricular-arterial coupling, pulmonary hypertension, and right ventricular (RV) remodeling/dysfunction. However, the relative prognostic significance of each of these pathophysiologic abnormalities in HFpEF is ...
Wilson Robert S - - 2013
Objective: Harm avoidance, a trait indicative of behavioral inhibition, is associated with disability and dementia in old age, but the basis of these associations is uncertain. We test the hypothesis that higher level of harm avoidance is associated with increased likelihood of cerebral infarction. Method: Older persons without dementia completed ...
Yang Bin B Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, - - 2013
To investigate the possible use of electrical impedance tomography (EIT) in monitoring focal cerebral infarction in a rabbit model. A model of focal cerebral infarction was established in eight New Zealand rabbits using a photochemical method without craniectomy. Focal cerebral infarction was confirmed by histopathological examination. Intracranial impedance variation was ...
van Horssen Pepijn P Academic Medical Center, Univ. of Amsterdam, - - 2013
Functional collateral vessels often stem from outward remodelling of pre-existing connections between perfusion territories. Knowledge of distribution and morphology of innate collateral connections may help identifying myocardial areas with protection against risk for ischemia. The coronary network of six healthy canine hearts was investigated with an imaging cryomicrotome. Innate collateral ...
Haddad Francois F Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, - - 2013
The objective of this study was to determine the factors independently associated with septal curvature in patients with pulmonary arterial hypertension (PAH). Eighty-five consecutive patients with PAH who had an echocardiogram and a right heart catheterization within 24 hours of each others were included in the study. Septal curvature was assessed ...
Brodie Bruce R BR The LeBauer Cardiovascular Research Foundation, Greensboro, North - - 2013
This study compares very late outcomes following primary percutaneous coronary intervention for ST-elevation myocardial infarction (STEMI) with stenting versus balloon angioplasty (BA). Stenting compared with BA for STEMI improves outcomes at 6-12 months, but comparisons beyond 6-12 months have not been studied. Recent studies have shown that stent thrombosis (ST) ...
Kawaguchi Naoto N Department of Radiology, Ehime University Graduate School of - - 2013
Background: The purpose of this study was to evaluate a personalized protocol with diluted contrast material (CM) for coronary computed tomography angiography (CTA). Methods and Results: One hundred patients with suspected coronary artery disease underwent retrospective electrocardiogram-gated coronary CTA on a 256-slice multidetector-row CT scanner. In the diluted CM protocol (n=50), the ...
Nam Julian J Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada. Electronic address: - - 2013
To present a review of out-of-hospital identification of ST-segment elevation myocardial infarction patients transported by emergency medical services with 12-lead ECG and advance notification versus standard or no cardiac monitoring. EMBASE, PubMed, and the Cochrane Library were searched, using controlled vocabulary and keywords. Randomized controlled trials and observational studies were ...
Fransson Eleonor I EI School of Health Sciences, Jönköping University, Jönköping, - - 2013
To describe and explore how partners rate their intimate relationship before and after the patients' first myocardial infarction. A further aim was to investigate the association between partners' rating of their intimate relationship and self-rated health. To date, information on how partners experience the intimate relationship before and after a ...
Freed Benjamin H - - 2013
Regadenoson is a vasodilator stress agent that selectively activates the A2A receptor. Compared to adenosine, regadenoson is easier to administer and results in fewer side effects. Although extensively studied in patients undergoing nuclear perfusion imaging (MPI), its use for perfusion cardiovascular magnetic resonance (CMR) is not well described. The aim ...
Hor Kan N - - 2013
Duchenne muscular dystrophy (DMD), an X-linked disorder affects approximately 1 in 5000 males, is universally associated with heart disease. We previously identified myocardial disease by late gadolinium enhancement (LGE) in DMD subjects at various stages of disease, but the true prevalence is unclear. Cardiovascular magnetic resonance (CMR) is well established ...
Nishi Hiroyuki H Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, - - 2013
Conventional coronary artery bypass grafting (CABG) using cardiopulmonary bypass and cardiac arrest is associated with higher mortality and morbidity rates in acute coronary syndrome (ACS) patients undergoing surgery. Although off-pump CABG (OPCAB) is beneficial for high-risk patients, its efficacy for ACS is unknown, with on-pump beating CABG an adjunctive method. ...
Mühlberger Volker V Department of Internal Medicine III (Cardiology), Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria, - - 2013
Concerning international comparison for the year 2011, Austria is situated under the top nations with 6,383 diagnostic coronary angiographies (CA), 2,407 percutaneous coronary interventions (PCI), and 47 transarterial aortic valve implantations (TAVI) per 1 million inhabitants in Europe. Although the number of TAVI increases rapidly since its first introduction in 2007 ...
Hashemi Nashmil N Department of Clinical Physiology, Karolinska University Hospital, Huddinge, Stockholm, - - 2013
Myocardial performance index (MPI) is a measure of combined systolic and diastolic myocardial function. In patients with coronary artery disease (CAD) an increase in MPI is consistent with myocardial dysfunction. The objectives of this study were to characterize the changes in MPI after coronary artery bypass graft (CABG) at rest ...
Makimoto Hisaki H 1Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, - - 2013
-The aim of this study was to evaluate in vivo contact force (CF), and the correlation of CF with impedance during left atrial (LA) 3D-electroanatomial mapping and ablation. -CF during point-by-point LA-mapping was assessed in 30 patients undergoing atrial fibrillation ablation. Operators were blinded to the real-time CF data. Data ...
Landesberg Giora G 1Division of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel. 2The Cardiovascular Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN. 3Division of Cardiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel. 4The Bio-Medical Engineering, The Technion, Haifa, - - 2013
Serum troponin concentrations predict mortality in almost every clinical setting they have been examined, including sepsis. However, the causes for troponin elevations in sepsis are poorly understood. We hypothesized that detailed investigation of myocardial dysfunction by echocardiography can provide insight into the possible causes of troponin elevation and its association ...
Toelg Ralph R Herzzentrum Segeberger Kliniken GmbH, Bad Segeberg, - - 2013
Aims: Safety and efficacy of percutaneous coronary interventions using the Pantera Lux paclitaxel-coated balloon has been demonstrated in the PEPPER first-in-man trial. This prospective, multicentre, clinical registry aims to evaluate its safety and efficacy in an international real-world setting in a larger cohort of patients. Methods and results: Between April ...
Joyce Emer E Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands, - - 2013
Left ventricular (LV) twist is emerging as a marker of global LV contractility after acute myocardial infarction (AMI). This study aimed to describe stress-induced changes in LV twist during dobutamine stress echocardiography (DSE) after AMI and investigate their association with LV reverse remodeling at 6 months follow-up. In 82 consecutive first ...
Tomai Fabrizio F European Hospital, Rome, - - 2013
Percutaneous coronary interventions (PCI) in patients with chronic kidney disease (CKD) have shown suboptimal results. Drug-eluting stents (DES) might reduce the rate of target vessel revascularization compared to bare metal stent (BMS) in CKD patients. However, given the multiple concomitant individual variables present in such patients, the comparison of neointimal ...
Rimensberger Caroline C Division of Cardiovascular Prevention, Rehabilitation and Sports Medicine, Swiss Cardiovascular Centre Bern, Inselspital, University Hospital and University of Bern, - - 2013
Ultra-endurance sports are becoming increasingly popular in middle-aged amateur athletes. Right ventricular (RV) arrhythmogenic remodelling has been described in high-level endurance athletes, like professional cyclists. The clinical relevance for amateurs is unknown. We investigated male amateur runners of the 2011 Grand Prix of Bern, a popular 10-mile race in Switzerland. ...
Gianetti Jacopo J Operative Unit of Cardiology, Fondazione Gabriele Monasterio, Ospedale del Cuore "G. Pasquinucci", Via Aurelia Sud, 54100 Massa, - - 2013
Von Willebrand factor (VWF) is an emerging risk factor in acute coronary syndromes. Platelet Function Analyzer (PFA-100) with Collagen/Epinephrine (CEPI) is sensitive to functional alterations of VWF and also identifies patients with high on-treatment platelet reactivity (HPR). The objective of this study was to verify the effect of double dose ...
Chin Chee Tang CT Duke Clinical Research Institute, Durham, NC; National Heart Centre Singapore, Singapore. Electronic address: - - 2014
Little is known about percutaneous coronary intervention (PCI) outcomes among patients presenting with an acute myocardial infarction (MI) with a history of prior PCI. Outcomes may differ depending on whether PCI is performed on a previously treated or de novo culprit lesion. We examined ST-segment elevation myocardial infarction (STEMI) and ...
Hofmann Robin R Karolinska Institutet, Department of Clinical Science and Education, Division of Cardiology, Södersjukhuset, Stockholm, Sweden. Electronic address: - - 2014
The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is recommended in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world. However, to date there is no conclusive evidence from adequately designed and powered trials supporting this practice. Existing data ...
Bose Abhishek A From the Division of Cardiology, the Cardiac Arrhythmia Service; - - 2013
CRT recipients with ICM have scar segments that may limit ventricular resynchronization and clinical response. The impact of myocardial viability at the LV pacing site on CRT response is poorly elucidated. A retrospective cohort of 160 ICM patients with single photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) prior to device ...
Larsen Torben Bjerregaard TB Department of Cardiology, Aalborg AF Study Group, Aalborg University Hospital, Denmark; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Aalborg, Denmark. Electronic address: - - 2013
Dabigatran may provide less protection against myocardial infarction than vitamin K antagonists (VKAs) in patients with atrial fibrillation. This may be particularly evident among 'switchers' to dabigatran from VKA, as a result of discontinuation effects. We identified in nationwide Danish registries a cohort of VKA-naïve 'new starters' on dabigatran (110mg ...
Aunes Maria M AstraZeneca R&D, Mölndal, Sweden. Electronic address: - - 2013
Effects on the atrial fibrillatory rate (AFR) were studied during infusion with the combined potassium and sodium channel blocker AZD7009. Patients with persistent atrial fibrillation (AF) were randomized to AZD7009 or placebo. Thirty-five patients converted to sinus rhythm (SR) and were matched to 35 non-converters. The mean AFR before conversion ...
Shilane D D Department of Health Research and Policy Stanford University School of Medicine Palo Alto, CA, USA - - - 2013
Aim: Patients with end-stage renal disease (ESRD) on maintenance dialysis have a high burden of coronary disease. Prior studies in non-dialysis patients show better outcomes in coronary artery bypass surgery using the internal mammary artery (IMA) compared with the saphenous vein graft (SVG), but less is known about outcomes in ...
Cooper Chad - - 2013
Cocaine is a potent sympathomimetic agent associated with the development of possible fatal cardiovascular complications. Dysrhythmias, acute myocardial infarction, hypertension and dilated cardiomyopathy are just some of many cardiovascular effects related to the abuse of cocaine. A 38-year-old Hispanic male with a past medical history of hypertension presented with a ...
Simon Erin L EL Department of Emergency Medicine, Akron General Medical Center, Akron, - - 2013
Freestanding emergency departments (FEDs) introduce a challenge to physicians who care for the patient with an ST-segment elevation myocardial infarction (STEMI) because treatment is highly time dependent. FEDs have no percutaneous coronary intervention (PCI) capabilities, which necessitates transfer to a PCI-capable facility or fibrinolysis. Our aim was to determine the ...
Verbrugge Frederik H - - 2013
In ambulatory patients with heart failure (HF) and reduced ejection fraction (rEF), renin-angiotensin system (RAS) and β-blockers at guideline-recommended target dose reduce all-cause mortality and readmissions. Benefits in HF with preserved ejection fraction (pEF), as well as uptitration after a hospitalization, remain uncertain. This study assesses the impact of RAS- ...
Qazi Umair U Department of Surgery, The Johns Hopkins University, Baltimore, - - 2013
While patient eligibility for carotid artery stenting (CAS) is well established, the intraoperative technique remains widely varied. The decision to perform poststent ballooning (PSB) is operator-dependent and often influenced by the interpretation of poststent angiography. While visually creating a greater luminal diameter, it is unclear whether PSB has immediate risks ...
Sarr Moustapha - - 2013
Coronary heart disease remains the leading cause of death in developed countries. In Africa, the disease continues to rise with varying rates of progression in different countries. At present, there is little available work on its juvenile forms. The objective of this work was to study the epidemiological, clinical and ...
Karimova Ann A Cardiothoracic Unit, Great Ormond Street Hospital for Children, London, United Kingdom. Electronic address: - - 2013
To describe the incidence and severity of right ventricular dysfunction (RVD) in pediatric ventricular assist device (VAD) recipients and to identify the preoperative characteristics associated with RVD and their effect on outcomes. Children bridged to transplantation from 2004 to 2011 were included. RVD was defined as the use of a ...
Carlson Nicholas N Department of Cardiology, Copenhagen University Hospital Herlev, The Copenhagen City Heart Study, Copenhagen University Hospital , - - 2013
Background. Elevated resting heart rate (RHR) is associated with cardiovascular mortality and morbidity. Assessment of heart rate (HR) from Holter recording may afford a more precise estimate of the effect of RHR on cardiovascular risk, as compared to casual RHR. Comparative analysis was carried out in an age-stratified subsample of ...
Opdahl Anders A Cardiology Division, Johns Hopkins University, Baltimore, MD; Department of Cardiology, Rikshospitalet, Oslo University Hospital, and University of Oslo, Oslo, - - 2013
To investigate the relationship between baseline resting heart rate and incidence of heart failure (HF) and global and regional left ventricular (LV) dysfunction. The association of resting heart rate to HF and LV function is not well described in an asymptomatic multi-ethnic population. Participants in the Multi-Ethnic Study of Atherosclerosis ...
Hansen Malene Kærslund - - 2013
The prognostic impact of acute kidney injury (AKI) on long-term clinical outcomes remains controversial. We examined the five-year risk of death, myocardial infarction, and stroke after elective cardiac surgery complicated by AKI. We conducted a cohort study among adult elective cardiac surgical patients without severe chronic kidney disease and/or previous ...
Komagamine Masahide M Department of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo - - - 2013
Purpose: Numerous difficulties remain associated with pediatric heart transplantation. Therefore, the development of a ventricular assist device (VAD) specific to these cases is extremely important for therapeutic effectiveness. We present 5 cases of severe heart failure that were managed by ventricular assist device implantation, as a bridge to transplantation.‚Ä©Methods: We ...
Gupta Navdeep N Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: - - 2013
Although cocaine ingestion may cause or contribute to myocardial infarction (MI), few contemporary data are available describing cocaine-associated MI. We describe the characteristics, management, and outcomes of patients with MI and recent cocaine use from the Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines (ACTION Registry-GWTG) program. ...
Shavelle David M DM Division of Cardiovascular Medicine, University of Southern California, Los Angeles, California. Electronic address: - - 2013
Primary percutaneous coronary intervention for ST elevation myocardial infarction (STEMI) is beneficial if performed in a timely manner. Self-transport patients with STEMI have prolonged treatment times compared with Emergency Medical Services-transported patients. This study evaluated self-transport patients with STEMI undergoing primary percutaneous coronary intervention to identify factors associated with prolonged ...
Moriel Mady M Department of Cardiology, Shaare Zedek Medical Center, The Hebrew University Hadassah Medical School, Jerusalem, Israel. Electronic address: - - 2013
We assessed the impact of aspiration thrombectomy (AT) in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention (PPCI) on major adverse cardiac events at 30 days and 1-year mortality in 517 consecutive patients who were included in the prospective, nationwide, multicenter, observational Acute Coronary Syndrome Israeli Survey ...
Mallat J - - 2013
Background: To investigate whether cardiac index (CI) and global end diastolic volume index (GEDVi) index determined from the same thermodilution curve are mathematically coupled during the infusion of an inotropic agent in critically ill patients. Methods: Seventeen patients were prospectively studied. CI and GEDVi were evaluated in triplicate by the ...
Gao Hang H Department of Cardiology, Liaocheng People's Hospital, Liaocheng 252000, PR - - 2013
This study was designed to investigate the predictive value of serum collagen biomarkers on the outcomes of acute ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI). Two hundred and ten patients with STEMI were successfully treated with PCI within 6 hrs ofthe onset of chest pain. The levels ...
Osadnik Tadeusz - - 2013
Data regarding the association between red cell distribution width (RDW) values and mortality in patients with stable coronary artery disease are scarce. We aimed to investigate the link between mortality and RDW in patients with stable coronary artery disease undergoing percutaneous coronary intervention (PCI). We analyzed 2550 consecutive patients with ...
O'Brien Emily C - - 2013
Background-Prior studies have found that obese patients have paradoxically lower in-hospital mortality after non-ST-segment-elevation myocardial infarction than their normal-weight counterparts, yet whether these associations persist long term is unknown.Methods and Results-We linked detailed clinical data for patients with non-ST-segment-elevation myocardial infarction aged ≥65 years in the Can Rapid Risk Stratification ...
Ahmed Mohamed M Heart, Lung and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, - - 2013
among patients with normal left ventricular (LV) ejection fraction (EF), the interposition of chronic, high-dose right ventricular apical (RVA) pacing may produce late EF decline. to test the hypothesis that LV dyssynchrony, defined echocardiographically and apparent early after interposition of pacing, would be greater among patients who subsequently demonstrated EF ...
Waldo Stephen W SW Department of Medicine, Division of Cardiology, Massachusetts General Hospital, Boston, MA. Electronic address: - - 2014
A posterior myocardial infarction (PMI) is associated with significant morbidity and delays in recognition may prevent the timely revascularization of these patients. The present study sought to evaluate the reperfusion times and in-hospital outcomes among patients with an isolated PMI. Clinical characteristics and reperfusion times were compared between those with ...
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