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Results 351 - 400 of 3782
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Meijs Loek Petrus Bartholomeus LP Catharina - - 2014
Ischemic preconditioning is a form of intrinsic cardioprotection where an episode of sublethal ischemia protects against subsequent episodes of ischemia. Identifying a clinical biomarker of preconditioning could have important clinical implications and prior work has focused on the electrocardiographic (ECG) ST-segment. However, the electrophysiology biomarker of preconditioning is increased action ...
Feher Attila - - 2014
Conducted vasodilation is essential to coordinate vascular resistance along distances to ensure adequate tissue perfusion. We hypothesized that conducted vasodilation of coronary resistance arteries declines with age. Coronary arterioles were dissected from right atrial appendage of patients (n=27) undergoing cardiac surgery. Arterioles (~100μm) were cannulated and pressurized (80-mmHg), and developed ...
- - 2014
Objective To investigate whether myocardial bridging(MB)is independently associated with coronary atherosclerosis proximal to MB in the left anterior descending coronary artery(LAD)identified by computed tomographic coronary angiography(CCTA). Methods From March 2011 to December 2012,patients(n=9 862)with suspected coronary disease underwent CCTA using dual-source CT scanner. The baseline clinical characteristics(age,gender,smoking history,presence of hypertension,dyslipidemia,diabetes ...
Carney Robert M RM Department of Psychiatry, St Louis, MO; Washington University School of Medicine, St Louis, MO. Electronic address: - - 2014
The purposes of this study were to identify nocturnal patterns of heart rate (HR) in depressed and nondepressed patients after an acute myocardial infarction (MI) and to determine which patterns, if any, are associated with all-cause mortality or recurrent infarction. Functional data analysis and model-based clustering methods were used to ...
Dueholm Margit M Department of Obstetrics and Gynecology, Aarhus University Hospital, Brendstrupgaardsvej 100, Aarhus N, 8200, Denmark. Electronic address: - - 2014
To evaluate outcome of invasive gynecological re-interventions after uterine artery embolisation (UAE) in relation to leiomyoma characteristics. A cohort of 114 women with symptomatic myomas underwent UAE. Myoma characteristics were determined by contrast-enhanced magnetic resonance imaging (MRI) before and 6 months after treatment. The median follow-up time after UAE was ...
Kolb Christof C Deutsches Herzzentrum, Klinik für Herz- und Kreislauferkrankungen, Faculty of Medicine, Technische Universität München, Munich, Germany. Electronic address: - - 2014
Detrimental effects of right ventricular (RV) apical pacing have directed the interest toward alternative pacing sites such as the RV mid-septum. As safety data are scarce for implantable cardioverter defibrillator (ICD) recipients the study aims to evaluate ICD lead performance in the mid-septal position. A total of 299 ICD recipients ...
Ringborn Michael M Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden; Center for Integrative Electrocardiology at Lund University (CIEL), Lund, Sweden; Thoracic Center, Blekingesjukhuset, Karlskrona, Sweden. Electronic address: - - 2014
In STEMI, grade-3 ischemia (G3) on admission ECG predicts larger infarct size (IS) than grade-2 (G2). We evaluated whether pre-hospital G3 and its temporal behavior are associated with IS and salvage after pPCI. In 401 STEMI patients, pre-hospital and pre-PCI ECGs were classified as G3 or G2. IS was assessed ...
Pautasso Enrique E Centro de Cardiologia Nuclear, Argentina. Electronic address: - - 2014
To assess whether a cold pressor test (CPT) could help identify patients at a high risk of cardiovascular events in a population without known coronary artery disease (CAD) with a normal myocardial perfusion scintigraphy (MPS). Our population consisted of 870 patients with a mean age of 59.3years with several CAD ...
Edwards Fred H FH The Society of Thoracic Surgeons, Chicago, Illinois. Electronic address: - - 2014
Recent observational studies show that patients with multivessel coronary disease have a long-term survival advantage with coronary artery bypass grafting (CABG) compared with percutaneous coronary intervention (PCI). Important nonfatal outcomes may also affect optimal treatment recommendation. CABG was compared with percutaneous catheter intervention by using a composite of death, myocardial ...
Kim Soo-Han SH 0000-0002-0893-732X Department of Internal Medicine, Inha University Hospital, Incheon, - - 2014
We investigated whether the presence of J wave on the surface electrocardiography (sECG) could be a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction (AMI). We performed a retrospective study of 317 patients diagnosed with AMI in a single center from 2009 to 2012. Among the enrolled ...
Bjerre Mette - - 2014
Abstract Objectives: High circulating levels of osteoprotegerin (OPG) carry prognostic impact in cohorts with various cardiovascular diagnoses. With the present study we aim to investigate the role of OPG within the scale of myocardial damage. Design: This study includes 219 consecutive patients with acute ST-elevation myocardial infarction (STEMI) randomized to ...
Cresci Sharon S 1Department of Medicine, Cardiovascular Division & Department of Genetics, Washington University School of Medicine, Saint Louis, - - 2014
-Clopidogrel is recommended after acute myocardial infarction (AMI) but has variable efficacy and safety, in part related to the effect of cytochrome P450 (CYP) polymorphisms on its metabolism. The effect of CYP polymorphisms on cardiovascular events among clopidogrel-treated patients after AMI remains controversial, and no studies to date have investigated ...
Nolte Froukje F Department of Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, The - - 2014
Aims: It has been argued that hyperaemic microvascular resistance (HMR), defined as the ratio of mean distal coronary pressure to flow velocity, is overestimated in the presence of a coronary stenosis compared to actual microvascular resistance (MR), due to neglecting collateral flow. We aimed to test the hypothesis that HMR ...
D'Ascenzo Fabrizio F Division of Cardiology, Department of Internal Medicine, Città Della Salute e Della Scienza, Turin, - - 2014
Aims: To establish the cardioprotective effect of remote ischaemic preconditioning (RIPC) in patients undergoing percutaneous coronary intervention (PCI). Methods and results: Pubmed (MEDLINE), Cochrane and Embase were systematically searched for randomised controlled trials of RIPC in patients undergoing PCI. Periprocedural myocardial infarction (PMI) was the primary endpoint (defined as troponin ...
Ho Hee Hwa HH Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore, - - 2014
Drug-eluting bioresorbable vascular scaffold (BVS) is a revolutionary treatment option for obstructive coronary artery disease in percutaneous coronary intervention. It restores blood flow to the myocardium but unlike permanent metallic stent, BVS dissolves in the body within 2 years. This allows the coronary vessel to regain its normal function and motion. ...
Lin Tsung-Hsien - - 2014
The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. In a Taiwan national-wide registry, 3093 ACS patients were enrolled. ...
Liu Xinbing - - 2014
Objective: To compare the therapeutic warfarin and aspirin efficacies for treatments of atrial fibrillation (AF) complicated with stable coronary heart disease particularly in older Chinese patients. Methods: In our prospective study 101 patients with AF and stable coronary heart disease older than 80 years were randomized into two groups. One ...
Saito Shigeru S Division of Cardiology, Shonan Kamakura General - - 2014
Background: Prasugrel is an antiplatelet agent that shows more prompt, potent, and consistent platelet inhibition than clopidogrel. The objective of this study was to confirm the efficacy and safety of prasugrel at loading/maintenance doses of 20/3.75mg. Methods and Results: Japanese patients (n=1,363) with acute coronary syndrome undergoing percutaneous coronary intervention were randomized ...
Stamboul Karim K Cardiology Department, University Hospital, Dijon, - - 2014
Silent atrial fibrillation (AF) has been suggested to be frequent after acute myocardial infarction (MI). Continuous ECG monitoring (CEM) has been shown to improve AF screening in patients at risk of stroke. We aimed to assess the incidence and prognosis of silent AF in patients with acute MI. All the ...
Wieringa Wouter G WG Thoraxcenter, Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen , The Netherlands - - 2014
In patients with ST-segment elevation myocardial infarction (STEMI), the time of onset of ischemia has been associated with myocardial infarction (MI) size. Myocardial blush grade (MBG) reflects myocardial response to ischemia/reperfusion injury, which may differ according to time of the day. The aim of our study was to explore the ...
Puymirat Etienne E aAssistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou, Department of Cardiology, Paris, Université Paris-Descartes bINSERM U-970 cAP-HP, Hôpital Saint Antoine, Department of Clinical Pharmacology and Unité de Recherche Clinique (URCEST) dUniversité Pierre et Marie Curie (UPMC-Paris 06) eAP-HP, Hôpital Bichat fParis, France, Université Paris-Diderot, Sorbonne Paris-Cité gINSERM U-698, Paris hUniversity Hospital Jean Minjoz, Department of Cardiology, Besançon iUniversity Hospital of Lille, Department of Cardiology, Lille jUniversity hospital of Nantes, Nantes kUniversity hospital of Nancy, Nancy lToulouse Rangueil University Hospital, Department of Cardiology, UMR1027, INSERM, Toulouse, - - 2014
A shorter time delay between onset of symptoms and first call for medical attention would be expected in patients with a history of ischemic heart disease (IHD). We aimed to determine whether time to first call for an ST-elevation myocardial infarction (STEMI) differed between patients with or without history of ...
Kukla Piotr P Department of Cardiology, Specialistic Hospital, Gorlice, - - 2014
A 72-year-old man with heart failure, left ventricular dysfunction (ejection fraction 20%), prior ischemic stroke, COPD, and exacerbation of chronic renal failure was admitted in our unit. Serum potassium was 6.1 mmol/L, calcium concentration was at the lower normal range 2.15 mmol/L, and NT-pro-BNP was 28,900 pg/mL. The surface 12-lead ...
Neven Kars K Dept. of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; Dept. of Rhythmology, Alfried Krupp Krankenhaus, Essen, Germany. Electronic address: - - 2014
Electroporation can be used as a non-thermal method to ablate myocardial tissue. However, like with all electrical ablation methods, determination of the energy supplied into the myocardium enhances the clinically required controllability over lesion creation. The purpose of this animal study was to investigate the relationship between magnitude of epicardial ...
Reeves Ryan R RR Department of Medicine, Division of Cardiovascular Medicine, University of California, San - - 2014
Objectives: To characterize the prevalence of thrombus burden, collateral vessels to the infarct-related artery, epicardial coronary artery flow, and myocardial perfusion in patients with angiographically confirmed definite stent thrombosis (ST), and to define their relationship with associated treatments and outcomes. Background: Angiographic characteristics of ST are not well defined. Methods: ...
Moore Jeremy P JP Division of Pediatric Cardiology, UCLA Medical Center. Electronic address: - - 2014
Tachycardia-induced cardiomyopathy (TIC) carries significant risk of morbidity and mortality, although full recovery is possible. Little is known about the myocardial recovery pattern. To determine the time course and predictors of myocardial recovery in pediatric TIC. An international multicenter study of pediatric TIC was conducted. Children ≤18 years with incessant ...
Brisco Meredith A MA Department of Medicine, Cardiovascular Division, Medical University of South Carolina, Charleston, South - - 2014
Although atrial arrhythmias (AAs) are common in heart failure, the incidence of AAs subsequent to the placement of left ventricular assist devices (LVADs) has not been elucidated. Patients receiving a HeartMate II LVAD in the bridge to transplant (n = 490) and destination therapy (n = 634) trials were included (n = 1125). AAs requiring treatment ...
Tonelli Marcello M Department of Medicine, University of Alberta, Edmonton, Canada; Department of Public Health Sciences, University of Alberta, Edmonton, Canada. Electronic address: - - 2014
Elucidation of the relationship between age, kidney function, and absolute coronary risk would facilitate efforts to promote chronic kidney disease (CKD) as a high-risk state for future vascular events and justify current recommendations for statin treatment in CKD. Population-based study. 1,268,538 people with data for estimated glomerular filtration rate and ...
Randall D A DA Centre for Health Research, School of Medicine, Blg 3 Campbelltown Campus, University of Western Sydney, Locked Bag 1797, Penrith, NSW 2751, Australia. Electronic address: - - 2014
We investigated disparities in rates of acute myocardial infarction (AMI) between Aboriginal and non-Aboriginal people in the 199 Statistical Local Areas (SLAs) in New South Wales, Australia. Using routinely collected and linked hospital and mortality data from 2002 to 2007, we developed multilevel Poisson regression models to estimate the relative ...
Hara Masahiko M Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, - - 2014
Few studies have investigated whether angiotensin II receptor blocker (ARB) is a practical alternative to angiotensin-converting enzyme inhibitor (ACEI) for long-term use after acute myocardial infarction (AMI) in real-world practice in the percutaneous coronary intervention era. We compared 5-year survival benefits of ACEI and ARB in patients with AMI registered ...
Hirai Taishi T Department of Medicine, Loyola University Chicago, Stritch School of Medicine, Loyola University Medical Center, Maywood, - - 2014
It is unknown whether recurrence of atrial fibrillation (AF) is related to severity of left ventricular diastolic dysfunction (LVDD) before ablation in patients with preserved left ventricular ejection fraction (LVEF). We tested the hypothesis that the presence and/or severity of LVDD before catheter ablation are related to AF recurrence during ...
Seth Ashok A Chairman - Cardiovascular Sciences & Chief Cardiologist, Fortis Escorts Heart Institute, Okhla Road, New Delhi 110025, India. Electronic address: - - 2014
Cardiovascular disease in Asia has reached epidemic proportions in recent years. Use of drug eluting stents in Asians has rapidly expanded with varying penetration rates across different countries. The XIENCE V(®) INDIA Study included 'real world' patients who underwent XIENCE V(®) stent implantation to assess short and intermediate term outcomes ...
Krepp Joseph M JM Greenberg Division of - - 2014
Left ventricular (LV) diastolic dysfunction (DD) is a known predictor of poor cardiovascular outcomes. Although ECG LV hypertrophy (LVH) is strongly associated with LV systolic dysfunction and heart failure, the relation of LV DD to ECG LVH is unclear. ECG LVH by Cornell product (CP) criteria was examined in a ...
Lambert Lauri J LJ Institut National d'Excellence en Santé et en Services Sociaux (INESSS), Montreal, Quebec, - - 2014
Inter-hospital transfer of patients with ST-elevation myocardial infarction (STEMI) for primary percutaneous coronary intervention (PPCI) is associated with longer delays to reperfusion, related partly to turnaround ('door-in' to 'door-out', DIDO) time at the initial hospital. As part of a systematic, province-wide evaluation of STEMI care, we examined DIDO times and ...
Sanders Robert A RA Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, - - 2014
To determine if the transesophageal atrial (A) wave amplitude or ventricular (V) wave amplitude can be used to guide optimal positioning of a transesophageal pacing catheter in dogs. Prospective clinical study. Fourteen client owned healthy dogs with a median weight of 15.4 kg (IQR = 10.6-22.4) and a median age of 12 months (IQR = 6-12). ...
Arnold Suzanne V SV Saint Luke's Mid America Heart Institute, Kansas City, MO, - - 2014
While patients with diabetes mellitus (DM) have more extensive coronary disease and worse survival after acute myocardial infarction (AMI) than patients without DM, data on whether they experience more angina are conflicting. We examined angina prevalence over the year following AMI among 3367 patients, including 1080 (32%) with DM, from ...
Barone Raffaella R aStudy of Coronary Blood Flow Unit bInterventional Cardiology, Az. Ospedaliera San Camillo Forlanini, Rome, - - 2014
Stress-induced ischemia may cause a decrease in left ventricular ejection fraction (EF). We evaluated the variation in early postexercise EF (S-EF) compared with rest EF (R-EF) in different clinical settings to detect ventricular dysfunction. We also correlated ventricular dysfunction with an angiographic score, the Syntax score, in a subgroup of ...
Lamberts Morton M Department of Cardiology, Gentofte University Hospital, Hellerup, Copenhagen, Denmark. Electronic address: - - 2014
To investigate the impact of atrial fibrillation (AF) and antithrombotic treatment on prognosis in patients with heart failure (HF) as well as vascular disease. HF, vascular disease and AF are pathophysiological related and understanding antithrombotic treatment in these conditions is crucial. In hospitalized patients with HF and co-existing vascular disease ...
Yalonetsky Sergey S Department of Cardiology, Rambam Medical Center, Haifa, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, - - 2014
Right ventricular (RV) infarction is associated with increased mortality. Functional mitral regurgitation (FMR) may complicate inferoposterior infarction with RV involvement leading to pulmonary hypertension and increased RV afterload, potentially exacerbating RV remodeling and dysfunction. We studied 179 patients with inferior wall left ventricular (LV) ST-elevation myocardial infarction and RV infarction. ...
Cavalcante João L JL Heart and Vascular Institute, University of Pittsburgh-UPMC, Pittsburgh, - - 2014
Cardiac magnetic resonance (CMR) identifies important prognostic variables in ischemic cardiomyopathy (ICM) patients such as left ventricular (LV) volumes, LV ejection fraction (LVEF), peri-infarct zone, and myocardial scar burden (MSB). It is unknown whether Doppler-based diastolic dysfunction (DDF) retains its prognostic value in ICM patients, in the context of current ...
Renzi Cristina C 1Department of Epidemiology, Regional Health Service, Lazio Region, Rome, - - 2014
/st>To evaluate whether public reporting of performance data was associated with a change over time in quality indicators for acute myocardial infarction (AMI) in Italian hospitals. /st>Pre-post evaluation of AMI indicators in the Lazio region, before and after disclosure of the Regional Outcome Evaluation Program, and a comparative evaluation versus ...
Angel Arenal A A Hospital General Universitario Gregorio Marañón, Madrid, - - 2014
Endo-epicardial substrate ablation reduces ventricular tachycardia (VT) recurrences, however not all patients in whom the epicardium is explored have VT substrate. Contrast-enhanced magnetic resonance imaging (ceMRI) is used to characterize VT substrate after myocardial infarction. To determine if epicardial VT substrate can be identified noninvasively by ceMRI based endo-epicardial signal ...
Taglieri Nevio N Istituto di Cardiologia, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Alma Mater Studiorum Università di Bologna, - - 2014
To evaluate the relationship between ECG patterns and infarct related artery (IRA) in an all-comer population with ST-segment elevation myocardial infarction (STEMI) and validate current criteria for identifying IRA (right coronary artery (RCA) versus left circumflex artery (LCA)) in inferior STEMI and for diagnosing left main (LM) or left anterior ...
Wijnbergen Inge I aDepartment of Cardiology, Catharina Hospital Eindhoven bDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven cAcademic Medical Center, University of Amsterdam, Amsterdam, the - - 2014
We aimed to investigate, in patients with ST-segment elevation myocardial infarction (STEMI), whether the previously reported clinical benefits of sirolimus-eluting stent(s) (SES) in terms of reducing a major adverse cardiac and cerebrovascular event (MACCE) compared with bare-metal stent(s) (BMS) were maintained over a 5-year time period. In the prospective single-centre ...
Yoshino Satoshi S aDepartment of Cardiovascular Medicine and Hypertension, Kagoshima University Hospital, Sakuragaoka, Kagoshima, Japan bDepartment of Internal Medicine, Division of Cardiovascular Diseases cDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics dDepartment of Experimental Pathology and Laboratory Medicine, Division of Genomics Shared Resource eDepartment of Internal Medicine, Division of Nephrology, Mayo Clinic and College of Medicine, Rochester, Minnesota, USA fDepartment of Cardiology, Ajou University Medical Center, Suwon, - - 2014
Single nucleotide polymorphisms (SNPs) are the most common source of genetic variation. Although microvascular pathology is associated with cardiovascular events, genetic phenotypes causing microvascular disease remain largely unknown. This study identifies sex-specific SNPs associated with coronary microvascular dysfunction. Six hundred and forty-three patients without significant obstructive coronary heart disease were ...
Moens Didier D aEmergency Department bHelicopter Emergency Medical Service - Centre Médical Héliporté de Bra-Sur-Lienne, Liège University Hospital cDepartment of Medical Informatics and Biostatistics dDepartment of Public Health, University of Liege, Liège, - - 2014
Primary prehospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We designed a prospective study involving patients with acute myocardial infarction aimed at the evaluation of the potential benefit of such primary HEMS interventions as compared ...
Krummen David E DE University of California San Diego, San Diego, CA; Veterans Affairs San Diego Healthcare System, San Diego, CA. Electronic address: - - 2014
We mapped human ventricular fibrillation (VF) to define mechanistic differences between episodes requiring defibrillation versus those that spontaneously terminate. VF is a leading cause of mortality, yet episodes may also self-terminate. We hypothesized that the initial maintenance of human VF is dependent upon the formation and stability of VF rotors. ...
Quinn Tom T Faculty of Health and Medical Sciences, University of Surrey, , Guildford, - - 2014
To describe patterns of prehospital ECG (PHECG) use and determine its association with processes and outcomes of care in patients with ST-elevation myocardial infarction (STEMI) and non-STEMI. Population-based linked cohort study of a national myocardial infarction registry. 288 990 patients were admitted to hospitals via emergency medical services (EMS) between ...
Loo Germaine G Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, - - 2014
We aimed to determine the prognostic implications of obstructive sleep apnea (OSA) diagnosed during the recovery phase of acute coronary syndrome (ACS). Patients presenting with ACS and treated with percutaneous coronary intervention were recruited prospectively for a home-based sleep study within 30days of hospital discharge. Major adverse cardiac and cerebrovascular ...
Guo Donglin D Lankenau Institute for Medical Research, Wynnewood, PA; College of Life Science, South-Central University for Nationalities, Wuhan, China. Electronic address: - - 2014
The late sodium current (INa-L) contributes importantly to rate-dependent change in action potential duration (APD) and transmural dispersion of repolarization (TDR). However, little is known about the mechanisms of increased APD rate-dependence and amplified TDR in left ventricular hypertrophy (LVH) and failure. The purpose of this study was to investigate ...
Faludi Réka R Faculty of Medicine, Heart Institute, University of Pécs, Pécs, Hungary. Electronic address: - - 2014
In systemic sclerosis (SSc), left ventricular diastolic dysfunction reflects primary myocardial involvement of the disease. We aimed to assess the abnormalities of the diastolic function, analyze the characteristics of the disease progression, and investigate the prognostic value of diastolic dysfunction in SSc patients. A total of 34 SSc patients (57 ...
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