Search Results
Results 351 - 400 of 3844
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Shams Issac I Healthcare Systems Engineering Group, Wayne State University, Detroit, MI, 48201, USA, - - 2014
Hospital readmission has become a critical metric of quality and cost of healthcare. Medicare anticipates that nearly $17 billion is paid out on the 20 % of patients who are readmitted within 30 days of discharge. Although several interventions such as transition care management have been practiced in recent years, the effectiveness ...
Kim Eun Young EY Department of Radiology, Gachon University Gil Hospital, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760, - - 2014
Information about myocardial perfusion in healthy hearts is essential for evaluating patients with ischemic heart disease. The purpose of this study was to determine the range and regional variability of myocardial perfusion in normal volunteers on dynamic perfusion computed tomography (CT). Myocardial perfusion was assessed in 19 healthy volunteers (age ...
Piccolo Raffaele R Department of Advanced Biomedical Sciences, Federico II University, Naples, - - 2014
We evaluated the relation between reperfusion indexes and right ventricular (RV) dysfunction in patients with inferior ST-segment elevation myocardial infarction (STEMI). We included patients with inferior STEMI undergoing percutaneous coronary intervention and right coronary artery as infarct-related artery. Myocardial reperfusion was evaluated by Thrombolysis In Myocardial Infarction (TIMI) flow, TIMI ...
Harskamp Ralf E RE Duke Clinical Research Institute, Durham, North Carolina; Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: - - 2014
Hybrid coronary revascularization (HCR) combines minimally invasive left internal mammary artery-to-left anterior descending coronary artery grafting with percutaneous coronary intervention of non-left anterior descending coronary arteries. The safety and efficacy of HCR in patients ≥65 years of age is unknown. In this study, patients aged ≥65 years were included who ...
Wolak Arik A Cardiology Department, Soroka University Medical Center, Beer-Sheva 84101, Israel; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, - - 2014
The negative predictive value of a normal myocardial perfusion image (MPI) for myocardial infarction or cardiac death is very high. However, it is unclear whether a normal MPI, reflecting non-compromised blood flow in the stable state, would have the same prognostic implications in smokers as in patients who do not ...
Nairooz Ramez R Department of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas. Electronic address: - - 2014
This study sought to investigate the relative safety and efficacy of bivalirudin versus heparin plus glycoprotein (GP) IIb/IIIa inhibitors in patients undergoing percutaneous coronary intervention (PCI) and in those with ST-segment elevation myocardial infarction (STEMI). The safety of bivalirudin in PCI, particularly in patients with STEMI, continues to be debated. ...
Ouyang Feifan F 1Askepios Klinik St. Georg, Hamburg, - - 2014
-VA originating from the anterosuperior left ventricular outflow tract (LVOT) represents a challenging location for catheter ablation. This study investigates mapping and ablation of ventricular arrythmias (VA) from anterosuperior LVOT via a transseptal approach. -This study included 27 patients with symptomatic VA, in whom 13 patients had previous failed ablations. ...
Hira Ravi S RS Baylor College of Medicine, Houston, TX, - - 2014
Following reperfusion therapy, early T wave inversions (TWI) have been shown to be a marker of successful reperfusion. We aimed to evaluate the relationship of TWI on the presenting ECG with spontaneous reperfusion as assessed by coronary angiography in patients with ST elevation (STE) myocardial infarction (STEMI). Data of 146 ...
Lingman Markus M Institute of Medicine, Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Medicine, Halland Hospital, Varberg, Sweden. Electronic address: - - 2014
To study effects of ischemia-reperfusion on ventricular electrophysiology in humans by three-dimensional electrocardiography. Fifty-seven patients with first-time acute anterior ST elevation myocardial infarction were monitored from admission and >24h after symptom onset with continuous vectorcardiography (VCG; modified Frank orthogonal leads). Global ventricular depolarization and repolarization (VR) measures were compared at ...
Auffret Vincent V CHU de Rennes, Service de Cardiologie et Maladies Vasculaires, Rennes, France; INSERM, U1099, Rennes, France; Université de Rennes 1, LTSI, Rennes, France. Electronic address: - - 2014
Previous studies investigating prehospital use of glycoprotein IIb/IIIa inhibitors (GPIs) in patients with ST-segment elevation myocardial infarction reached conflicting conclusions. The benefit of this strategy in addition to in-ambulance loading of dual-antiplatelet therapy remains controversial. The aim of this study was to analyze data from a prospective registry of patients ...
Rusu Alexandru A Applied Signal Processing Group, Swiss Federal Institute of Technology, CH-1015 Lausanne, - - 2014
Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate on the ability to capture AF when pacing the septum. Three ...
Verdoia Monica - - 2014
Periprocedural myocardial infarction still occurs in patients undergoing percutaneous coronary intervention. However, very little is known about the role of biomarkers possibly predicting this complication. Serum uric acid has been associated with enhanced inflammatory status, higher thrombotic risk and poorer outcome after percutaneous coronary intervention. We therefore, evaluated the association ...
Tabara Yasuharu Y aCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto bDepartment of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, - - 2014
Increasing blood pressure (BP) variability is reported to be a cardiovascular risk factor. However, the clinical implications of postprandial hypotension (PHYPO), a commonly observed BP variability in elderly persons, are poorly understood. Here, we investigated the possible associations between postprandial BP decline and asymptomatic cerebral damage in community residents. Study ...
Uhm Jae-Sun JS Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Clinical significance of first-degree atrioventricular block (AVB) have not been known in patients with hypertension. This study was performed to elucidate long-term prognosis of first-degree AVB in patients with hypertension. We included 3816 patients (mean age, 61.0 ± 10.6 years; men, 47.2%) with hypertension. We reviewed their ECGs and measured the PR ...
Silverman Michael G MG Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Baltimore, - - 2014
The aim of this study was to evaluate the impact of coronary artery calcium (CAC) burden and regional distribution on the need for and type of future coronary revascularization-percutaneous versus surgical (coronary artery bypass graft [CABG])-among asymptomatic subjects. The need for coronary revascularization and the chosen mode of revascularization are thought ...
Papaioannou Georgios I GI Athens Medical Center, Cardiac Catheterization Laboratory, Athens, - - 2014
The Hellenic Heart Registry on Percutaneous Coronary Interventions (HHR-PCI) was a prospective, observational registry of patients with stable angina or acute coronary syndromes who underwent percutaneous coronary intervention (PCI) between January 2008 and October 2010. HHR-PCI was a database that used a secure web-based interface for data entry by individual ...
Brouwer Emily S ES From the aDepartment of Pharmacy Practice and Science, Institute for Pharmaceutical Outcomes and Policy, University of Kentucky, Lexington, KY; bDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC; cDepartment of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC; and dDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, - - 2014
Cohort studies have demonstrated greater risk of myocardial infarction (MI) associated with specific antiretroviral use, while meta-analyses of randomized controlled trials (RCTs) have not. These differences may be due to inherent biases in the observational study design or to the limited duration of randomized trials. We conducted a new-user, active-comparator ...
Ozcan Sedat S Sedat Ozcan, Department of Cardiovascular Surgery, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, - - 2014
Atrial fibrillation (AF) is the most common arrhythmia seen after coronary artery surgery. The purpose this study was to determine incidence of AF that develops after coronary surgery and the factors affecting its development. Four hundred and forty eight patients who had coronary bypass surgery between February 2007 and September ...
Charles Janice J Family Medicine Research Centre, University of Sydney, New South - - 2014
Cardiomyopathy is a disease that causes the heart muscle to become weak and ineffective, reducing the heart's ability to pump blood through the body and possibly leading to heart failure. The rate at which cardiomyopathy was recorded by general practitioner (GP) participants in the BEACH program has not changed significantly ...
Assadpour Piranfar Mohammad M Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran - - 2014
The relationship between QT dispersion and myocardial ischemia is still controversial. Therefore, we aimed to investigate the relationship between QTd and the severity and extent of myocardial ischemia. In this cross-sectional study, 141 patients having symptoms of CAD who referred to our medical center during 2009-2010, and were examined with ...
Choudhry Niteesh K - - 2014
Substantial racial and ethnic disparities in cardiovascular care persist in the United States. For example, African Americans and Hispanics with cardiovascular disease are 10-40 percent less likely than whites to receive secondary prevention therapies, such as aspirin and beta-blockers. Lowering copayments for these therapies improves outcomes among all patients who have ...
Vihonen Hanna - - 2014
The current study was to investigate the blood glucose changes in ultra-acute phase in patients with ST-elevation myocardial infarction (STEMI) and its associations with patient outcome. This study was a retrospective population-based observational study utilizing prospectively collected registry data complemented with laboratory data. All adult patients with STEMI treated by ...
Hong Young Joon YJ Division of Cardiology, Chonnam National University School of Medicine, Gwangju, - - 2014
We evaluated the two-year clinical outcomes in patients with angiographically intermediate lesions according to the plaque burden and treatment strategy. We prospectively enrolled patients with angiographically intermediate lesions (diameter stenosis 30-70%) with an intravascular ultrasound (IVUS) minimum lumen area (MLA) <4 mm(2) with 50-70% plaque burden of 16 Korean percutaneous ...
Brenyo Andrew A From the Cardiology Division of the Department of Medicine, University of Rochester Medical Center, NY (A. Brenyo, V.K., A.-C.R., M.R., W.Z., D.T.H., A.J.M., I.G., S.M.); Department of Cardiology, Greenville University Health System, SC (A. Brenyo); Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.-C.P., D.K., S.D.S.); Cardiology Department, Rabin Medical Center, Petah Tikva, Israel (A. Barsheshet); and Department of Cardiology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel (A. - - 2014
There are limited data regarding factors associated with spontaneous left ventricular reverse remodeling (S-LVRR) among mildly symptomatic heart failure (HF) patients and its prognostic implications on clinical outcomes. Best subsets logistic regression analysis was used to identify factors associated with S-LVRR (defined as ≥15% reduction in left ventricular end-systolic volume ...
Murthy Venkatesh L VL University of Michigan, Ann Arbor, MI; Brigham & Women's Hospital, Boston, - - 2014
Coronary microvascular dysfunction (CMD) is a prevalent and prognostically important finding in patients with symptoms suggestive of coronary artery disease (CAD). The relative extent to which CMD affects both genders is largely unknown. We investigated 405 men and 813 women referred for evaluation of suspected CAD with no previous history ...
Carlsen Esben A EA Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: - - 2014
In patients with ST-elevation myocardial infarction (STEMI) the amount of myocardial area at risk (MaR) indicates the maximal potential loss of myocardium if the coronary artery remains occluded. During the time course of infarct evolution ischemic MaR is replaced by necrosis, which results in a decrease in ST segment elevation ...
Cullington Damien D Department of Cardiology, Postgraduate Medical Institute, Hull York Medical School, University of Hull, Kingston upon Hull, United Kingdom. Electronic address: - - 2014
This study sought to investigate the relationship between resting ventricular rate and mortality in patients with chronic heart failure (CHF) and reduced left ventricular ejection fraction (LVEF) who were in sinus rhythm (SR) or atrial fibrillation (AF). Slower heart rates are associated with better survival in patients with CHF in ...
Ukena Christian C Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Kirrberger Str. 1, 66421, Homburg/Saar, Germany, - - 2014
Myocarditis might be associated with increased markers of myocardial injury. However, data on novel biomarkers, such as high-sensitive Troponin T (hs-TnT) or Copeptin, are lacking. This study aimed to determine the diagnostic and prognostic utility of biomarkers in patients with suspected myocarditis. Seventy patients with clinically suspected myocarditis (age 43.4 ± 14 years, ...
Guerra Elena E Deutsches Herzzentrum München, Technische Universität, Lazarettstrasse 36, 80636, Munich, - - 2014
The aim of the study was to assess the frequency and predictive factors of microvascular obstruction (MVO) in patients with non-ST-segment elevation myocardial infarction (NSTEMI). This study included 190 consecutive patients with NSTEMI who underwent percutaneous coronary intervention (PCI) within 24 h after admission and cardiac magnetic resonance (CMR) imaging, 4.1 days ...
Ogah Okechukwu S OS Division of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria; Soweto Cardiovascular Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: - - 2014
The aim of this study was to determine the contemporary profile, clinical characteristics, and intrahospital outcomes of acute heart failure (AHF) in an African urban community. There are limited data on the current burden and characteristics of AHF in Nigerian Africans. Comprehensive and detailed clinical and sociodemographic data were prospectively ...
Park Kyung Woo KW Seoul National University Hospital, Seoul, - - 2014
To test whether the newly developed platinum chromium-based everolimus-eluting stent (PtCr-EES) is noninferior to the cobalt chromium-based zotarolimus-eluting stent (CoCr-ZES) in all-comers receiving percutaneous coronary intervention (PCI). PtCr provides improved radial strength, conformability, and visibility compared to CoCr alloy, but PtCr-based stents have not been tested in a wide range ...
Schutt Robert C RC Department of Medicine, University of Virginia, Charlottesville, - - 2014
To determine the impact of coronary collaterals in stable angina. Whether spontaneously visible coronary collaterals are associated with long-term clinical outcomes in stable angina remains unclear. We prospectively enrolled patients with stable angina referred for coronary angiography and followed them clinically for 1 year. A total of 1,134 consecutive patients ...
Santos Paulo Cjl - - 2014
Polymorphisms in the LPA gene were associated with coronary artery disease (CAD). However, there are differences in the allelic frequencies, Lp(a) levels, and significant association with CAD according to ethnic groups. In this scenario, the main aim of this study was to assess the influence of the LPA polymorphisms on ...
Ikonomidis Ignatios I From the 2nd Cardiology Department (I.I., S.T., I.P., G.P., J.P., D.K., M.A.-N., J.L.) and 4th Department of Internal Medicine, Rheumatology Unit (P.K.), Attikon Hospital, University of Athens, Athens, Greece; and Department of Pharmaceutical Chemistry, University of Athens School of Pharmacy, Athens, Greece (I.A., C.K.). - - 2014
We investigated the effects of anakinra, an interleukin-1 receptor antagonist, on coronary and left ventricular function in coronary artery disease (CAD) patients with rheumatoid arthritis. In a double-blind crossover trial, 80 patients with rheumatoid arthritis (60 with CAD and 20 without) were randomized to a single injection of anakinra or ...
Almeida André Luiz Cerqueira de AL Johns Hopkins University, Baltimore, MD, - - 2014
Background: Subclinical cardiovascular disease is prevalent in patients with Metabolic Syndrome (MetSyn). Left ventricular (LV) circumferential strain (εCC) and longitudinal strain (εLL), assessed by Speckle Tracking Echocardiography (STE), are indices of systolic function: shortening is indicated by negative strain, and thus, the more negative the strain, the better the LV ...
Meijs Loek Petrus Bartholomeus LP Catharina - - 2014
Ischemic preconditioning is a form of intrinsic cardioprotection where an episode of sublethal ischemia protects against subsequent episodes of ischemia. Identifying a clinical biomarker of preconditioning could have important clinical implications and prior work has focused on the electrocardiographic (ECG) ST-segment. However, the electrophysiology biomarker of preconditioning is increased action ...
Feher Attila - - 2014
Conducted vasodilation is essential to coordinate vascular resistance along distances to ensure adequate tissue perfusion. We hypothesized that conducted vasodilation of coronary resistance arteries declines with age. Coronary arterioles were dissected from right atrial appendage of patients (n=27) undergoing cardiac surgery. Arterioles (~100μm) were cannulated and pressurized (80-mmHg), and developed ...
- - 2014
Objective To investigate whether myocardial bridging(MB)is independently associated with coronary atherosclerosis proximal to MB in the left anterior descending coronary artery(LAD)identified by computed tomographic coronary angiography(CCTA). Methods From March 2011 to December 2012,patients(n=9 862)with suspected coronary disease underwent CCTA using dual-source CT scanner. The baseline clinical characteristics(age,gender,smoking history,presence of hypertension,dyslipidemia,diabetes ...
Carney Robert M RM Department of Psychiatry, St Louis, MO; Washington University School of Medicine, St Louis, MO. Electronic address: - - 2014
The purposes of this study were to identify nocturnal patterns of heart rate (HR) in depressed and nondepressed patients after an acute myocardial infarction (MI) and to determine which patterns, if any, are associated with all-cause mortality or recurrent infarction. Functional data analysis and model-based clustering methods were used to ...
Dueholm Margit M Department of Obstetrics and Gynecology, Aarhus University Hospital, Brendstrupgaardsvej 100, Aarhus N, 8200, Denmark. Electronic address: - - 2014
To evaluate outcome of invasive gynecological re-interventions after uterine artery embolisation (UAE) in relation to leiomyoma characteristics. A cohort of 114 women with symptomatic myomas underwent UAE. Myoma characteristics were determined by contrast-enhanced magnetic resonance imaging (MRI) before and 6 months after treatment. The median follow-up time after UAE was ...
Pautasso Enrique E Centro de Cardiologia Nuclear, Argentina. Electronic address: - - 2014
To assess whether a cold pressor test (CPT) could help identify patients at a high risk of cardiovascular events in a population without known coronary artery disease (CAD) with a normal myocardial perfusion scintigraphy (MPS). Our population consisted of 870 patients with a mean age of 59.3years with several CAD ...
Kolb Christof C Deutsches Herzzentrum, Klinik für Herz- und Kreislauferkrankungen, Faculty of Medicine, Technische Universität München, Munich, Germany. Electronic address: - - 2014
Detrimental effects of right ventricular (RV) apical pacing have directed the interest toward alternative pacing sites such as the RV mid-septum. As safety data are scarce for implantable cardioverter defibrillator (ICD) recipients the study aims to evaluate ICD lead performance in the mid-septal position. A total of 299 ICD recipients ...
Ringborn Michael M Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden; Center for Integrative Electrocardiology at Lund University (CIEL), Lund, Sweden; Thoracic Center, Blekingesjukhuset, Karlskrona, Sweden. Electronic address: - - 2014
In STEMI, grade-3 ischemia (G3) on admission ECG predicts larger infarct size (IS) than grade-2 (G2). We evaluated whether pre-hospital G3 and its temporal behavior are associated with IS and salvage after pPCI. In 401 STEMI patients, pre-hospital and pre-PCI ECGs were classified as G3 or G2. IS was assessed ...
Kim Soo-Han SH 0000-0002-0893-732X Department of Internal Medicine, Inha University Hospital, Incheon, - - 2014
We investigated whether the presence of J wave on the surface electrocardiography (sECG) could be a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction (AMI). We performed a retrospective study of 317 patients diagnosed with AMI in a single center from 2009 to 2012. Among the enrolled ...
Edwards Fred H FH The Society of Thoracic Surgeons, Chicago, Illinois. Electronic address: - - 2014
Recent observational studies show that patients with multivessel coronary disease have a long-term survival advantage with coronary artery bypass grafting (CABG) compared with percutaneous coronary intervention (PCI). Important nonfatal outcomes may also affect optimal treatment recommendation. CABG was compared with percutaneous catheter intervention by using a composite of death, myocardial ...
Cresci Sharon S 1Department of Medicine, Cardiovascular Division & Department of Genetics, Washington University School of Medicine, Saint Louis, - - 2014
-Clopidogrel is recommended after acute myocardial infarction (AMI) but has variable efficacy and safety, in part related to the effect of cytochrome P450 (CYP) polymorphisms on its metabolism. The effect of CYP polymorphisms on cardiovascular events among clopidogrel-treated patients after AMI remains controversial, and no studies to date have investigated ...
Bjerre Mette - - 2014
Abstract Objectives: High circulating levels of osteoprotegerin (OPG) carry prognostic impact in cohorts with various cardiovascular diagnoses. With the present study we aim to investigate the role of OPG within the scale of myocardial damage. Design: This study includes 219 consecutive patients with acute ST-elevation myocardial infarction (STEMI) randomized to ...
Lin Tsung-Hsien - - 2014
The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. In a Taiwan national-wide registry, 3093 ACS patients were enrolled. ...
Ho Hee Hwa HH Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore, - - 2014
Drug-eluting bioresorbable vascular scaffold (BVS) is a revolutionary treatment option for obstructive coronary artery disease in percutaneous coronary intervention. It restores blood flow to the myocardium but unlike permanent metallic stent, BVS dissolves in the body within 2 years. This allows the coronary vessel to regain its normal function and motion. ...
D'Ascenzo Fabrizio F Division of Cardiology, Department of Internal Medicine, Città Della Salute e Della Scienza, Turin, - - 2014
Aims: To establish the cardioprotective effect of remote ischaemic preconditioning (RIPC) in patients undergoing percutaneous coronary intervention (PCI). Methods and results: Pubmed (MEDLINE), Cochrane and Embase were systematically searched for randomised controlled trials of RIPC in patients undergoing PCI. Periprocedural myocardial infarction (PMI) was the primary endpoint (defined as troponin ...
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