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James Owen Julian - - 2014
ABSTRACTObjective:Emergency department (ED) patients with symptoms of cardiac ischemia often require a second cardiac troponin (cTn) measurement to rule out non-ST elevation myocardial infarction. We measured the total turnaround time and the component event times following the ordering of the second cTn level to ED discharge to identify root causes ...
Pinelli Arnaldo A Research Unit "Iraklis Galatoulas" - Department of Medical Biotechnology and Translational Medicine, University of Milan, Via Vanvitelli 32, 20129 - Milan, Italy, - - 2014
Background/Aim: Acute myocardial infarction (AMI) is associated with increased coagulation which in the presence of unstable atheroma or endothelial damage leads to occlusive coronary vessel thrombosis. AMI is usually characterized by increased levels of catecholamines. It is possible there may be a link between catecholamines and hypercoagulation, but this still ...
Dedkov Eduard I EI Department of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Rockefeller Building, Room 215E, Northern Boulevard, Old Westbury, NY 11568-8000, USA. - - 2014
An increasing body of evidence indicates that left ventricular (LV) remodeling, especially the degree of reactive myocardial hypertrophy after myocardial infarction (MI), differs in males and females. Surprisingly, to date, the sex-specific post-MI alterations of the coronary vasculature remain undetermined. Therefore, we tested the hypothesis that adaptive coronary arteriolar and ...
Inci S S Department of Cardiology, Aksaray State Hospital, Aksaray, Turkey. - - 2014
Percutaneous and surgical reintervention after coronary artery bypass grafting (CABG) is frequent. The purpose of this study was to determine the predictors of reintervention in patients with symptoms of recurrent ischemia after coronary artery bypass graft surgery (CABG). The data of 20000 patients who had coronary angiography (CAG) from 2003 ...
Yetgin T T Department of Cardiology, Erasmus MC, Thoraxcentre, Room Ee-2355, Dr. Molewaterplein 50-60, 3015 GE, Rotterdam, The - - 2014
Medical discharge management of acute coronary syndromes (ACS) remains suboptimal outside randomised trials and constitutes an essential quality benchmark for ACS. We sought to evaluate the rates of key guideline-recommended pharmacological agents after ACS and characteristics associated with optimal treatment at discharge. The Rijnmond Collective Cardiology Research (CCR) registry is ...
Akkaya Mehmet M University of Utah, Carma (Comprehensive Arrhythmia Research and Management) Center, Salt Lake City, Utah, USA. - - 2014
Objectives: The extent of left atrial (LA) wall structural remodeling (fibrosis) detected by late gadolinium enhancement-magnetic resonance imaging (LGE-MRI) is correlated with advanced atrial fibrillation (AF). The concomitant occurrence of AF and left ventricular (LV) dysfunction is not uncommon. We studied the effect of LA fibrosis, a confounder of both ...
Westmoreland Andrew H AH Carrier Air Wing Seven, Naval Air Station Oceana, Virginia Beach, VA, USA. - - 2014
Coronary emergencies at sea requiring air evacuation are not uncommon. On board a Nimitz-class aircraft carrier while in a remote location, an active duty sailor suffered a myocardial infarction. A medical evacuation by helicopter was necessary. Transfer proved difficult due to the ship's location, poor flying conditions, and the patient's ...
Hsu Po-Chao PC Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan ; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan ; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, - - 2014
Patients with coronary ectasia (CE) usually have coexisting coronary stenosis resulting in myoischemia. Coronary collateral plays an important role in protecting myocardium from ischemia and reducing cardiovascular events. However, limited studies investigate the role of CE in coronary collaterals development. We evaluated 1020 consecutive patients undergoing coronary angiography and 552 ...
Xiao Junjie J Regeneration Lab and Experimental Center of Life Sciences, Shanghai University Shanghai 200444, China ; Shanghai Key Laboratory of Bio-Energy Crops, School of Life Science, Shanghai University Shanghai 200444, - - 2014
Acute myocardial infarction (AMI) is a most serious cardiovascular disease with high morbidity and mortality. Novel biomarkers for AMI are explored continuous. MicroRNAs (miRNAs, miRs) are present in the circulation in a consistent, stable, and reproducible manner, attracting major interest of using circulating miRNAs as biomarkers. In plasma, miR-208a and ...
Khosoosi Niaki Mohammadreza M Department of cardiology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, - - 2014
Background: Early diagnosis of right ventricle (RV) involvement in inferior myocardial infarction (Inf MI) is very critical. This study was performed to evaluate the clinical findings of Inf MI with or without RV infarction. Methods: From September 2010 to September 2012, 195 patients with definite diagnosis of Inf MI were ...
Showkathali Refai R aDepartment of Cardiology, The Essex Cardiothoracic Centre, Essex bAnglia Ruskin University, Chelmsford, - - 2014
Very few randomized trials have analysed the outcome of primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI) in very elderly patients (≥80 years). An observational study was performed to evaluate the outcome of PPCI in patients of at least 80 years of age who were admitted to ...
Al-Salam Suhail S Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, Abu Dhabi, United Arab - - 2014
Myocardial infarction (MI) is the most serious manifestation of coronary artery disease and the cause of significant mortality and morbidity worldwide. Galectin-1(GAL-1), a divalent 14.5-kDa protein, is present both inside and outside cells, and has both intracellular and extracellular functions. Hypoxia inducible factor-1 alpha (HIF-1α) is a transcription factor mediating ...
Honda Tsuyoshi T 0000-0003-0404-5452 Department of Cardiology, Cardiovascular Center, National Hospital Organization Kumamoto Medical Center, 1-5 Ninomaru, Chuo-ku, Kumamoto 860-0008, - - 2014
Background. Acute myocardial infarction (AMI) is accompanied by excessive production of catecholamines, which is characterized by a hypokalemic dip. A polymorphism of the adrenergic receptor has also been reported to be associated with target lesion revascularization (TLR) after coronary intervention. Subjects and Methods. We enrolled 276 consecutive patients with AMI ...
Maffei Silvia S 0000-0002-1900-5069 Department of Cardiology, University Hospital Azienda Ospedaliera Universitaria Senese (AOUS), Viale M. Bracci 16, 53100 Siena, - - 2014
Rett syndrome (RTT) is a devastating neurodevelopmental disorder with a 300-fold increased risk rate for sudden cardiac death. A subclinical myocardial biventricular dysfunction has been recently reported in RTT by our group and found to be associated with an enhanced oxidative stress (OS) status. Here, we tested the effects of ...
Jan Carmen C Gorgas Memorial Institute for Health Studies, Panamá City, - - 2014
To evaluate the association of a nationwide comprehensive smoking ban (CSB) and tobacco tax increase (TTI) on the risk of acute myocardial infarctions (AMI) in Panama for the period of 2006 - 2010 using hospital admissions data. Data of AMI cases was gathered from public and private hospitals in the ...
Hotchkiss Joel W JW School of Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, - - 2014
To quantify the contributions of prevention and treatment to the trends in mortality due to coronary heart disease in Scotland. Retrospective analysis using IMPACTSEC, a previously validated policy model, to apportion the recent decline in coronary heart disease mortality to changes in major cardiovascular risk factors and to increases in ...
Cesaroni Giulia G Department of Epidemiology, Lazio Regional Health Service, 00198 Rome, - - 2014
To study the effect of long term exposure to airborne pollutants on the incidence of acute coronary events in 11 cohorts participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Prospective cohort studies and meta-analysis of the results. Cohorts in Finland, Sweden, Denmark, Germany, and Italy. 100 ...
Cho Yun-Kyeong YK Department of Internal Medicine, Keimyung University School of Medicine, Daegu, - - 2014
While drug-eluting stents (DESs) have shown favorable outcomes in ST-segment elevation myocardial infarction (STEMI) compared to bare metal stents (BMSs), there are concerns about the risk of stent thrombosis (ST) with DESs. Because intravascular ultrasound (IVUS) guidance may help optimize stent placement and improve outcomes in percutaneous coronary intervention (PCI) ...
Subban Vijayakumar V Consultant, Department of Cardiology, Institute of Cardio-Vascular Diseases, Madras Medical Mission, Chennai, - - 2014
To assess the feasibility and outcomes of primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) in Indian Scenario. Between January 2005 and December 2012, consecutive STEMI patients who underwent PPCI within 12 h of onset of chest pain were prospectively enrolled in a PPCI registry. Patient demographics, risk ...
Koul Sasha S Department of Cardiology, Lund University, Skåne University Hospital Lund, - - 2014
Early reperfusion in the setting of an ST-elevation myocardial infarction (STEMI) is of utmost importance. However, the effects of early versus late reperfusion in this patient group undergoing primary percutaneous coronary intervention (PCI) have so far been inconsistent in previous studies. The purpose of this study was to evaluate in ...
Manek Megha M Department of Family Medicine, Guthrie/Robert Packer Hospital, Sayre, Pennsylvania, - - 2014
A 20-year-old Caucasian male patient presented after a single episode of syncope. His heart rate was 40 beats per minute. ECG showed new onset complete heart block. A temporary pacer was placed. He had a macular rash on the body from past 2 weeks and was diagnosed with contact dermatitis. ...
Taghizadeh Asl Mina - - 2014
We prospectively studied a group of patients with myocardial infarction (MI), who were candidates for surgical revascularization, to compare the efficacy of dobutamine gated myocardial SPECT with dobutamine stress echocardiography (DSE) for the detection of myocardial viability. We investigated 224 segments from 14 patients with MI using resting echocardiography and ...
Ben-Amotz Ron R Department of Veterinary Clinical Sciences, The Ohio State University Columbus, OH, - - 2014
Bilirubin was previously considered a toxin byproduct of heme catabolism. However, a mounting body of evidence suggests that at physiological doses, bilirubin is a powerful antioxidant and anti-atherosclerotic agent. Recent clinical studies have shown that human beings with genetically-induced hyperbilirubinemia (Gilbert Syndrome) are protected against coronary heart disease. The purpose ...
Tarazón Estefanía E Cardiocirculatory Unit, Instituto de Investigación Sanitaria Hospital Universitario La Fe, Valencia, - - 2014
The atrium is the major site of ANP synthesis, which has been said to increase in heart failure as a result of increased production in the left ventricular (LV) myocardium. This is a key issue related to its diagnostic and prognostic capabilities. We aimed to evaluate protein levels of proANP ...
Hosseini Seyyed Mohsen SM Department of Statistics and Epidemiology, Isfahan University of Medical Sciences, Skin Diseases and Leishmaniasis Research Center, - - 2014
Cardiovascular diseases are the highest ranking cause of mortality. The prevalence of cardiovascular diseases is increasing among people in developed and developing countries. Since left ventricular hypertrophy is one of the risk factors leading to extremely dangerous heart diseases and even sudden death at early ages, investigating its contributing factors ...
Mobeirek Abdulelah Fahad AF Dr. Abdulelah Fahad Mobeirek, Cardiac Sciences, King Saud University,, PO Box 93254 Riyadh 11673,, Saudi Arabia, F: 966.11-4671158, - - 2014
To describe the distribution of body mass index (BMI) and its relationship with clinical features, management, and in-hospital outcomes of patients admitted with acute coronary syndromes (ACS). The Saudi Project for Assessment of Coronary Events is a prospective registry. ACS patients admitted to 17 hospitals from December 2005-2007 were included ...
Hess Connie N CN Duke Clinical Research Institute, Durham, - - 2014
Data regarding sex-based outcomes after percutaneous coronary intervention (PCI) for myocardial infarction are mixed. We sought to examine whether sex differences in outcomes exist in contemporary practice. We examined acute myocardial infarction patients undergoing PCI between April 2010 and October 2012 at 210 US hospitals participating in the Treatment with ...
Kolte Dhaval D Department of Medicine, New York Medical College, Valhalla, - - 2014
Limited information is available on the contemporary and potentially changing trends in the incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction (STEMI). We queried the 2003-2010 Nationwide Inpatient Sample databases to identify all patients ≥40 years of age with STEMI and cardiogenic shock. Overall and age-, sex-, ...
Ribeiro Antonio Luiz P AL Department of Internal Medicine, Medical School, Universidade Federal de Minas Gerais, - - 2014
Electrocardiography has been considered an important tool in the management of Chagas disease (ChD) patients, although its value in elderly infected patients is unknown. This study was designed to investigate the prevalence and prognostic value of electrocardiographic abnormalities in Trypanosoma cruzi infected and noninfected older adults. We studied 1462 participants ...
Huang Jian J Cardiac Rhythm Management Laboratory, Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, - - 2014
The mechanisms that maintain long duration ventricular fibrillation (LDVF) are unclear. The difference in distribution of the Purkinje system in dogs and pigs was explored to determine if Purkinje activation propagates to stimulate working myocardium (WM) during LDVF and WM pacing. In-vivo extracellular recordings were made from 1044 intramural plunge ...
Namgung June J Division of Cardiology, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of - - 2014
Electrocardiogram (ECG) manifestations of takotsubo cardiomyopathy (TC) produce ST-segment elevation or T-wave inversion, mimicking acute coronary syndrome (ACS). We describe the ECG manifestation of TC, including ECG evolution, and its different points from ACS. We studied 37 consecutive patients (age 67 ± 15 years, range 23-89, M:F = 12:25) from ...
Kim Yeongsic Y Departments of Laboratory Medicine, The Catholic University of Korea, Uijeongbu St. Mary's Hospital, 271, Cheon bo-Ro, Uijeong bu, Korea, 480-717; phone: 82 31 820 3159; fax: 82 31 847 6266; email: - - 2014
The amount of heart-type fatty acid-binding protein (FABP3) in cardiomyocytes may affect the prognosis of patients with coronary atherosclerosis. In this study, we examined whether single nucleotide polymorphisms (SNPs) of the FABP3 gene were prognostic factors in patients with coronary atherosclerosis. We enrolled 100 patients with myocardial infarction and coronary ...
Nadel James J University of Notre Dame Australia, - - 2014
Acute coronary syndrome (ACS) is a significant contributor to both morbidity and mortality in Australia. Generally speaking, sufferers of ACS who live in rural areas and are treated at rural hospitals have poorer outcomes than those living in metropolitan areas. To characterise the differences in the management and outcomes of ...
Wysocka Anna A Department of Cardiology, Medical University of Lublin, Lublin, - - 2014
Background The aim of this study was to evaluate whether -108C/T polymorphism of the paraoxonase 1 (PON1) gene and the plasma enzyme activity are risk factors for adverse cardiac events after coronary artery bypass grafting (CABG). Material and Methods Seventy-one patients with coronary heart disease (CHD) undergoing CABG were enrolled ...
Machaalany Jimmy - - 2014
Studies assessing ischemic mitral regurgitation (IMR) comprised of heterogeneous population and evaluated IMR in the subacute setting. The incidence of early IMR in the setting of primary PCI, its progression and clinical impact over time is still undetermined. We sought to determine the predictors and prognosis of early IMR after ...
Sattarzadeh R R Cardiology Department of Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, - - 2014
Estimation of left ventricular end-diastolic pressure (LVEDP) among patients with mitral valve disease may help to explain their symptoms. However, conventional Doppler measurements have limitations in predicting LVEDP in this group of patients. The aim of this study was to construct a Doppler-derived LVEDP prediction model based on the combined ...
Sherwood Matthew W MW Division of Cardiovascular Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, - - 2014
P2Y12 antagonist therapy improves outcomes in acute myocardial infarction (MI) patients. Novel agents in this class are now available in the US. We studied the introduction of prasugrel into contemporary MI practice to understand the appropriateness of its use and assess for changes in antiplatelet management practices. Using ACTION Registry-GWTG ...
Chan Kim H KH Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; The Heart Research Institute, Sydney, New South Wales, Australia; Sydney Medical School, The University of Sydney, Sydney, New South Wales, - - 2014
Endothelial progenitor cells (EPCs) are implicated in protection against vascular disease. However, studies using angiography alone have reported conflicting results when relating EPCs to epicardial coronary artery disease (CAD) severity. Moreover, the relationship between different EPC types and the coronary microcirculation is unknown. We therefore investigated the relationship between EPC ...
Hsu Heng-Jung HJ Department of Nephrology, Chang Gung Memorial Hospital, Keelung 20401, Taiwan ; The Graduate Institute of Clinical Medical Sciences, Chang Gung University Medical College, Taoyuan 33302, Taiwan ; Department of Medicine, Chang Gung University, Taoyuan 33302, - - 2014
The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Patients with vasospasm were older and had higher peripheral ...
Kormi Immi I Oral and Maxillofacial Department, Oulu University Hospital, Oulu, - - 2013
Serum matrix metalloproteinases (MMP-8, MMP-7) and their regulators may be associated with the risk of incident cardiovascular disease events. Doxycycline can be used as matrix metalloproteinase (MMP) inhibitor independent of its antimicrobial activity. We aimed to investigate serum inflammatory biomarkers during 4 months of doxycycline therapy in coronary bypass patients. Thirty-one ...
Donal Erwan E Département de Cardiologie & CIC-IT U 804, Hôpital Pontchaillou, CHU de Rennes, rue Henri-Le-Guillou, 35000 Rennes, France; LTSI, Université Rennes 1, INSERM 1099, Rennes, France; Société française de cardiologie, Paris, France. Electronic address: - - 2013
Karolinska Rennes (KaRen) is a prospective observational study to characterize heart failure patients with preserved ejection fraction (HFpEF) and to identify prognostic factors for long-term mortality and morbidity. To report characteristics and echocardiography at entry and after 4-8weeks of follow-up. Patients were included following an acute heart failure presentation with ...
Johansson Isabelle I Cardiology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital Solna, N3:06, SE-171 76, Stockholm, - - 2013
To analyse the long-term outcome, risk factor panorama, and treatment pattern in patients with heart failure (HF) with and without type 2 diabetes (T2DM) from a daily healthcare perspective. Patients with (n = 8809) and without (n = 27 465) T2DM included in the Swedish Heart Failure Registry (S-HFR) 2003-2011 due to a physician-based HF ...
Cervinka Pavel P First Department of Internal Medicine-Cardioangiology, Faculty Hospital Hradec Králové, Hradec Králové, Czech Republic; Department of Cardiology, Krajská zdravotní a.s., Masaryk hospital and UJEP, Ústí nad Labem, Czech Republic. Electronic address: - - 2014
The objective of our study was to assess whether optical coherence tomography (OCT) guidance could guide intervention to avoid balloon angioplasty and stenting during primary percutaneous coronary intervention. One hundred patients with ST-segment elevation myocardial infarction and thrombus-containing lesion were enrolled in this study. Thrombus aspiration was performed in all ...
Suhail Mohammed Sa MS Mohammed SA Suhail, Mark W Wilson, Steven W Hetts, Maythem Saeed, Department of Radiology and Biomedical Imaging, School of Medicine, University of California San Francisco, CA 94107-5705, United - - 2013
To compare the acute changes in circumferential and longitudinal strain after exposing a coronary artery to various interventions in swine. Percutaneous balloon angioplasty catheter was guided to location aid device (LAD) under X-ray fluoroscopy to create different patterns of ischemic insults. Pigs (n = 32) were equally divided into 4 ...
Simpson Monica M Palm Beach Gardens Medical Center, Palm Beach Gardens, - - 2013
An evidence-based quality initiative to decrease heart failure 30-day readmissions was implemented at a hospital in Florida. Heart failure education and postdischarge telephone contact were provided to patients determined to be at high risk of readmission using risk stratification tools. The rate during the project decreased 13% as compared to ...
Cuschieri Justin R JR Louis Stokes VA Medical Center, Cleveland, Ohio, - - 2013
The use of antiplatelet agents for secondary prevention of cardiovascular events increases the risk of gastrointestinal (GI) bleeding. Our aim was to identify risk factors for acute GI bleeding in patients who have had a myocardial infarction and were prescribed clopidogrel following discharge from the hospital. Data was collected on ...
Gasevic Danijela - - 2013
Little is known on whether there are ethnic differences in outcomes following percutaneous coronary intervention (PCI) and coronary artery bypass grafting surgery (CABG) after acute myocardial infarction (AMI). We compared 30-day and long-term mortality, recurrent AMI, and congestive heart failure in South Asian, Chinese and White patients with AMI who ...
Lee Jun-Won JW Division of Cardiology, Yonsei University Wonju College of Medicine, Wonju, - - 2014
Recent studies suggest that the intracoronary administration of bone marrow (BM)-derived mesenchymal stem cells (MSCs) may improve left ventricular function in patients with acute myocardial infarction (AMI). However, there is still argumentative for the safety and efficacy of MSCs in the AMI setting. We thus performed a randomized pilot study ...
Chung Suryeun S Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
This study evaluated the outcomes of off-pump coronary artery bypass surgery (OPCAB) with severe left ventricular dysfunction using composite bilateral internal thoracic artery grafting. From January 2001 to December 2008, 1,842 patients underwent primary isolated OPCAB with composite bilateral internal thoracic artery grafting. A total of 131 of these patients ...
Gedik Nilguen N Institut für Pathophysiologie, Universitätsklinikum Essen, Essen, - - 2013
Ischemic postconditioning (PoCo) and cyclosporine A (CysA) given prior to reperfusion reduce myocardial infarct size after ischemia/reperfusion. Ischemic postconditioning's protection is characterized by better preservation of mitochondrial respiration and calcium retention capacity. Protection by CysA is not entirely clear. Cyclosporine A inhibits not only mitochondrial permeability transition pore (mPTP) opening ...
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