Search Results
Results 301 - 350 of 3784
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Gunn Jarmo J Heart Center, Turku University Hospital , Turku , - - 2014
Aim. This study was planned to compare the clinical characteristics and outcome of patients on warfarin treatment for atrial fibrillation (AF) undergoing coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). Methods. This is a retrospective analysis of 121 patients who underwent isolated CABG and 301 patients who underwent ...
Correia Luis Cláudio Lemos LC Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, - - 2014
Background: The incremental prognostic value of plasma levels of C-reactive protein (CRP) in relation to GRACE score has not been established in patients with acute coronary syndrome (ACS) with non-ST segment elevation. Objective: To test the hypothesis that CRP measurements at admission increases the prognostic value of GRACE score in ...
Minicucci Marcos F - - 2014
Background: The effects of modern therapy on functional recovery after acute myocardial infarction (AMI) are unknown. Objectives: To evaluate the predictors of systolic functional recovery after anterior wall AMI in patients undergoing modern therapy (reperfusion, aggressive platelet antiaggregant therapy, angiotensin-converting enzyme inhibitors and beta-blockers). Methods: A total of 94 consecutive ...
Criqui Michael H MH From the Department of Family and Preventive Medicine, University of California, San Diego, La Jolla (M.H.C., J.O.D., M.A.A., J.H.I.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle (R.M.); San Diego Veterans Affairs Healthcare System, CA (J.H.I); The Heart Center, Saint Francis Hospital, Roslyn, NY (A.G.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (K.P.C.); Geffen School of Medicine, University of California at Los Angeles (P.S., K.E.W.); and Division of Cardiology, University of California, Irvine - - 2014
To evaluate the predictive value of abdominal aortic calcium (AAC) for incident cardiovascular disease (CVD) independent of coronary artery calcium (CAC). We evaluated the association of AAC with CVD in 1974 men and women aged 45 to 84 years randomly selected from the Multi-Ethnic Study of Atherosclerosis participants who had ...
Acet Halit H 1Department of Cardiology, Dicle Universty Faculty of Medicine, Diyarbakır, - - 2014
The aim of this study was to evaluate the relationship between hematologic indices and the Global Registry of Acute Coronary Events (GRACE) score in patients with ST-segment elevation myocardial infarction (STEMI). A total of 800 patients who consecutively and retrospectively presented with STEMI within 12 hours of symptom onset. After ...
Lin Tsung-Hsien TH Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, No.100 Tzyou 1st Road, Kaohsiung, 80708, Taiwan, - - 2014
In-hospital bleeding (IHB) is associated with the risk of subsequent cardiovascular events (CVE) in acute coronary syndrome (ACS). We investigated whether increased risk of CVE by IHB is influenced by chronic kidney disease (CKD) or both have detrimental effects on CVE. In a Taiwan national-wide registry, 2819 ACS patients were ...
Koller L L Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, - - 2014
Heart failure with preserved ejection fraction (HFpEF) has a different pathophysiological background compared to heart failure with reduced ejection fraction (HFrEF). Tailored risk prediction in this separate heart failure group with a high mortality rate is of major importance. Inflammation may play an important role in the pathogenesis of HFpEF ...
Hammer-Hansen Sophia S Department of Health and Human Services, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 10 Center Drive, Bldg 10, RM B1D416, Bethesda, MD 20892-1061, - - 2014
Area-at-risk (AAR) measurements often rely on T2-weighted images, but subtle differences in T2 may be overlooked with this method. To determine the differences in oedema between salvaged and infarcted myocardium, we performed quantitative T2 mapping of the AAR. We also aimed to determine the impact of reperfusion time on T2 ...
Masoudi Frederick A - - 2014
Trials comparing implantable cardioverter-defibrillator (ICD) therapy with cardiac resynchronization therapy with a defibrillator (CRT-D) are limited to selected patients treated at centers with extensive experience. To compare outcomes after CRT-D versus ICD therapy in contemporary practice. Retrospective cohort study using the National Cardiovascular Data Registry's ICD Registry linked with Medicare ...
Casamian-Sorrosal Domingo D Langford Cardio-Respiratory Unit, Small Animal Hospital, Langford Veterinary Services, School of Veterinary Science, University of Bristol, Langford BS40 5DU, United Kingdom. Electronic address: - - 2014
The aim of the study was to report normal two-dimensional, M-mode, and Doppler echocardiographic findings from a large cohort of healthy, manually restrained, adult pet rabbits. Forty healthy pet rabbits [22 Dwarf Lops (DL), 14 French Lops (FL) and 4 Alaskan (AL)] underwent a full physical examination and conscious two-dimensional, ...
Lincoff A Michael AM Cleveland Clinic Coordinating Center for Clinical Research (C5Research), Cleveland, OH, - - 2014
Delcasertib is a selective inhibitor of delta-protein kinase C (delta-PKC), which reduced infarct size during ischaemia/reperfusion in animal models and diminished myocardial necrosis and improved reperfusion in a pilot study during primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI). A multicentre, double-blind trial was performed in patients ...
Laser Kai T KT Center for Congenital Heart Defects, Heart and Diabetes Center Northrhine-Westfalia, Ruhr-University of Bochum, Georgstr.11, Bad Oeynhausen 32545, - - 2014
Left ventricular rotation is an interesting mechanism to investigate patients with heart disease. In children, reference values have to be defined prior to assess pathology. One hundred and seventy-four healthy individuals (0-20 years) were investigated by two-dimensional speckle tracking echocardiography, percentiles were created addressing the amount and time-to-peak values (TTP) ...
Basuray Anupam A University Hospitals Case Medical Center, Harrington Heart and Vascular Institute, Cleveland, OH; Cleveland Clinic Foundation, Cleveland, - - 2014
We hypothesized that heart failure (HF) patients who recover left ventricular function (HF-Recovered) have a distinct clinical phenotype, biology and prognosis compared to HF with reduced ejection fraction (HF-REF) and HF with preserved ejection fraction (HF-PEF). The Penn Heart Failure Study (PHFS) is a prospective cohort of 1,821 chronic HF ...
Steiner Ivo I The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty, Hospital Hradec Králové, Czech Republic. Electronic address: - - 2014
Thrombus aspiration in the setting of primary percutaneous coronary intervention is a recently recommended technique that facilitates thrombus removal from the culprit lesions in acute myocardial infarction (AMI) patients. Thrombectomy specimens from 50 patients with symptoms of AMI lasting usually not more than 12 h were examined by methods of ...
Kim Eun Young EY Department of Radiology, Gachon University Gil Hospital, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760, - - 2014
Information about myocardial perfusion in healthy hearts is essential for evaluating patients with ischemic heart disease. The purpose of this study was to determine the range and regional variability of myocardial perfusion in normal volunteers on dynamic perfusion computed tomography (CT). Myocardial perfusion was assessed in 19 healthy volunteers (age ...
Shams Issac I Healthcare Systems Engineering Group, Wayne State University, Detroit, MI, 48201, USA, - - 2014
Hospital readmission has become a critical metric of quality and cost of healthcare. Medicare anticipates that nearly $17 billion is paid out on the 20 % of patients who are readmitted within 30 days of discharge. Although several interventions such as transition care management have been practiced in recent years, the effectiveness ...
Wolak Arik A Cardiology Department, Soroka University Medical Center, Beer-Sheva 84101, Israel; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, - - 2014
The negative predictive value of a normal myocardial perfusion image (MPI) for myocardial infarction or cardiac death is very high. However, it is unclear whether a normal MPI, reflecting non-compromised blood flow in the stable state, would have the same prognostic implications in smokers as in patients who do not ...
Ouyang Feifan F 1Askepios Klinik St. Georg, Hamburg, - - 2014
-VA originating from the anterosuperior left ventricular outflow tract (LVOT) represents a challenging location for catheter ablation. This study investigates mapping and ablation of ventricular arrythmias (VA) from anterosuperior LVOT via a transseptal approach. -This study included 27 patients with symptomatic VA, in whom 13 patients had previous failed ablations. ...
Harskamp Ralf E RE Duke Clinical Research Institute, Durham, North Carolina; Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: - - 2014
Hybrid coronary revascularization (HCR) combines minimally invasive left internal mammary artery-to-left anterior descending coronary artery grafting with percutaneous coronary intervention of non-left anterior descending coronary arteries. The safety and efficacy of HCR in patients ≥65 years of age is unknown. In this study, patients aged ≥65 years were included who ...
Auffret Vincent V CHU de Rennes, Service de Cardiologie et Maladies Vasculaires, Rennes, France; INSERM, U1099, Rennes, France; Université de Rennes 1, LTSI, Rennes, France. Electronic address: - - 2014
Previous studies investigating prehospital use of glycoprotein IIb/IIIa inhibitors (GPIs) in patients with ST-segment elevation myocardial infarction reached conflicting conclusions. The benefit of this strategy in addition to in-ambulance loading of dual-antiplatelet therapy remains controversial. The aim of this study was to analyze data from a prospective registry of patients ...
Nairooz Ramez R Department of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas. Electronic address: - - 2014
This study sought to investigate the relative safety and efficacy of bivalirudin versus heparin plus glycoprotein (GP) IIb/IIIa inhibitors in patients undergoing percutaneous coronary intervention (PCI) and in those with ST-segment elevation myocardial infarction (STEMI). The safety of bivalirudin in PCI, particularly in patients with STEMI, continues to be debated. ...
Hira Ravi S RS Baylor College of Medicine, Houston, TX, - - 2014
Following reperfusion therapy, early T wave inversions (TWI) have been shown to be a marker of successful reperfusion. We aimed to evaluate the relationship of TWI on the presenting ECG with spontaneous reperfusion as assessed by coronary angiography in patients with ST elevation (STE) myocardial infarction (STEMI). Data of 146 ...
Lingman Markus M Institute of Medicine, Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Medicine, Halland Hospital, Varberg, Sweden. Electronic address: - - 2014
To study effects of ischemia-reperfusion on ventricular electrophysiology in humans by three-dimensional electrocardiography. Fifty-seven patients with first-time acute anterior ST elevation myocardial infarction were monitored from admission and >24h after symptom onset with continuous vectorcardiography (VCG; modified Frank orthogonal leads). Global ventricular depolarization and repolarization (VR) measures were compared at ...
Piccolo Raffaele R Department of Advanced Biomedical Sciences, Federico II University, Naples, - - 2014
We evaluated the relation between reperfusion indexes and right ventricular (RV) dysfunction in patients with inferior ST-segment elevation myocardial infarction (STEMI). We included patients with inferior STEMI undergoing percutaneous coronary intervention and right coronary artery as infarct-related artery. Myocardial reperfusion was evaluated by Thrombolysis In Myocardial Infarction (TIMI) flow, TIMI ...
Uhm Jae-Sun JS Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Clinical significance of first-degree atrioventricular block (AVB) have not been known in patients with hypertension. This study was performed to elucidate long-term prognosis of first-degree AVB in patients with hypertension. We included 3816 patients (mean age, 61.0 ± 10.6 years; men, 47.2%) with hypertension. We reviewed their ECGs and measured the PR ...
Tabara Yasuharu Y aCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto bDepartment of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, - - 2014
Increasing blood pressure (BP) variability is reported to be a cardiovascular risk factor. However, the clinical implications of postprandial hypotension (PHYPO), a commonly observed BP variability in elderly persons, are poorly understood. Here, we investigated the possible associations between postprandial BP decline and asymptomatic cerebral damage in community residents. Study ...
Brouwer Emily S ES From the aDepartment of Pharmacy Practice and Science, Institute for Pharmaceutical Outcomes and Policy, University of Kentucky, Lexington, KY; bDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC; cDepartment of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC; and dDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, - - 2014
Cohort studies have demonstrated greater risk of myocardial infarction (MI) associated with specific antiretroviral use, while meta-analyses of randomized controlled trials (RCTs) have not. These differences may be due to inherent biases in the observational study design or to the limited duration of randomized trials. We conducted a new-user, active-comparator ...
Charles Janice J Family Medicine Research Centre, University of Sydney, New South - - 2014
Cardiomyopathy is a disease that causes the heart muscle to become weak and ineffective, reducing the heart's ability to pump blood through the body and possibly leading to heart failure. The rate at which cardiomyopathy was recorded by general practitioner (GP) participants in the BEACH program has not changed significantly ...
Choudhry Niteesh K - - 2014
Substantial racial and ethnic disparities in cardiovascular care persist in the United States. For example, African Americans and Hispanics with cardiovascular disease are 10-40 percent less likely than whites to receive secondary prevention therapies, such as aspirin and beta-blockers. Lowering copayments for these therapies improves outcomes among all patients who have ...
Rusu Alexandru A Applied Signal Processing Group, Swiss Federal Institute of Technology, CH-1015 Lausanne, - - 2014
Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate on the ability to capture AF when pacing the septum. Three ...
Verdoia Monica - - 2014
Periprocedural myocardial infarction still occurs in patients undergoing percutaneous coronary intervention. However, very little is known about the role of biomarkers possibly predicting this complication. Serum uric acid has been associated with enhanced inflammatory status, higher thrombotic risk and poorer outcome after percutaneous coronary intervention. We therefore, evaluated the association ...
Silverman Michael G MG Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Baltimore, - - 2014
The aim of this study was to evaluate the impact of coronary artery calcium (CAC) burden and regional distribution on the need for and type of future coronary revascularization-percutaneous versus surgical (coronary artery bypass graft [CABG])-among asymptomatic subjects. The need for coronary revascularization and the chosen mode of revascularization are thought ...
Papaioannou Georgios I GI Athens Medical Center, Cardiac Catheterization Laboratory, Athens, - - 2014
The Hellenic Heart Registry on Percutaneous Coronary Interventions (HHR-PCI) was a prospective, observational registry of patients with stable angina or acute coronary syndromes who underwent percutaneous coronary intervention (PCI) between January 2008 and October 2010. HHR-PCI was a database that used a secure web-based interface for data entry by individual ...
Vihonen Hanna - - 2014
The current study was to investigate the blood glucose changes in ultra-acute phase in patients with ST-elevation myocardial infarction (STEMI) and its associations with patient outcome. This study was a retrospective population-based observational study utilizing prospectively collected registry data complemented with laboratory data. All adult patients with STEMI treated by ...
Hong Young Joon YJ Division of Cardiology, Chonnam National University School of Medicine, Gwangju, - - 2014
We evaluated the two-year clinical outcomes in patients with angiographically intermediate lesions according to the plaque burden and treatment strategy. We prospectively enrolled patients with angiographically intermediate lesions (diameter stenosis 30-70%) with an intravascular ultrasound (IVUS) minimum lumen area (MLA) <4 mm(2) with 50-70% plaque burden of 16 Korean percutaneous ...
Assadpour Piranfar Mohammad M Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran - - 2014
The relationship between QT dispersion and myocardial ischemia is still controversial. Therefore, we aimed to investigate the relationship between QTd and the severity and extent of myocardial ischemia. In this cross-sectional study, 141 patients having symptoms of CAD who referred to our medical center during 2009-2010, and were examined with ...
Ozcan Sedat S Sedat Ozcan, Department of Cardiovascular Surgery, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, - - 2014
Atrial fibrillation (AF) is the most common arrhythmia seen after coronary artery surgery. The purpose this study was to determine incidence of AF that develops after coronary surgery and the factors affecting its development. Four hundred and forty eight patients who had coronary bypass surgery between February 2007 and September ...
Ukena Christian C Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Kirrberger Str. 1, 66421, Homburg/Saar, Germany, - - 2014
Myocarditis might be associated with increased markers of myocardial injury. However, data on novel biomarkers, such as high-sensitive Troponin T (hs-TnT) or Copeptin, are lacking. This study aimed to determine the diagnostic and prognostic utility of biomarkers in patients with suspected myocarditis. Seventy patients with clinically suspected myocarditis (age 43.4 ± 14 years, ...
Guerra Elena E Deutsches Herzzentrum München, Technische Universität, Lazarettstrasse 36, 80636, Munich, - - 2014
The aim of the study was to assess the frequency and predictive factors of microvascular obstruction (MVO) in patients with non-ST-segment elevation myocardial infarction (NSTEMI). This study included 190 consecutive patients with NSTEMI who underwent percutaneous coronary intervention (PCI) within 24 h after admission and cardiac magnetic resonance (CMR) imaging, 4.1 days ...
Murthy Venkatesh L VL University of Michigan, Ann Arbor, MI; Brigham & Women's Hospital, Boston, - - 2014
Coronary microvascular dysfunction (CMD) is a prevalent and prognostically important finding in patients with symptoms suggestive of coronary artery disease (CAD). The relative extent to which CMD affects both genders is largely unknown. We investigated 405 men and 813 women referred for evaluation of suspected CAD with no previous history ...
Brenyo Andrew A 1Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, NY; Greenville University Health System, Greenville, - - 2014
-There are limited data regarding factors associated with spontaneous left ventricular reverse remodeling (S-LVRR) among mildly symptomatic heart failure (HF) patients and its prognostic implications on clinical outcomes. -Best subsets logistic regression analysis was used to identify factors associated with SLVRR (defined as ≥ 15% reduction in left ventricular end ...
Carlsen Esben A EA Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: - - 2014
In patients with ST-elevation myocardial infarction (STEMI) the amount of myocardial area at risk (MaR) indicates the maximal potential loss of myocardium if the coronary artery remains occluded. During the time course of infarct evolution ischemic MaR is replaced by necrosis, which results in a decrease in ST segment elevation ...
Cullington Damien D Department of Cardiology, Postgraduate Medical Institute, Hull York Medical School, University of Hull, Kingston upon Hull, United Kingdom. Electronic address: - - 2014
This study sought to investigate the relationship between resting ventricular rate and mortality in patients with chronic heart failure (CHF) and reduced left ventricular ejection fraction (LVEF) who were in sinus rhythm (SR) or atrial fibrillation (AF). Slower heart rates are associated with better survival in patients with CHF in ...
Ogah Okechukwu S OS Division of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria; Soweto Cardiovascular Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: - - 2014
The aim of this study was to determine the contemporary profile, clinical characteristics, and intrahospital outcomes of acute heart failure (AHF) in an African urban community. There are limited data on the current burden and characteristics of AHF in Nigerian Africans. Comprehensive and detailed clinical and sociodemographic data were prospectively ...
Schutt Robert C RC Department of Medicine, University of Virginia, Charlottesville, - - 2014
To determine the impact of coronary collaterals in stable angina. Whether spontaneously visible coronary collaterals are associated with long-term clinical outcomes in stable angina remains unclear. We prospectively enrolled patients with stable angina referred for coronary angiography and followed them clinically for 1 year. A total of 1,134 consecutive patients ...
Ikonomidis Ignatios I 12nd Cardiology Department, Attikon Hospital, University of Athens, Athens, - - 2014
-We investigated the effects of anakinra, an interleukin-1 (IL-1) receptor antagonist, on coronary and left ventricular (LV) function in coronary artery disease patients (CAD) with rheumatoid atrhritis (RA). - In a double-blind cross-over trial, 80 RA patients, (60 with CAD and 20 without) were randomized to a single injection of ...
Park Kyung Woo KW Seoul National University Hospital, Seoul, - - 2014
To test whether the newly developed platinum chromium-based everolimus-eluting stent (PtCr-EES) is noninferior to the cobalt chromium-based zotarolimus-eluting stent (CoCr-ZES) in all-comers receiving percutaneous coronary intervention (PCI). PtCr provides improved radial strength, conformability, and visibility compared to CoCr alloy, but PtCr-based stents have not been tested in a wide range ...
Almeida André Luiz Cerqueira de AL Johns Hopkins University, Baltimore, MD, - - 2014
Background: Subclinical cardiovascular disease is prevalent in patients with Metabolic Syndrome (MetSyn). Left ventricular (LV) circumferential strain (εCC) and longitudinal strain (εLL), assessed by Speckle Tracking Echocardiography (STE), are indices of systolic function: shortening is indicated by negative strain, and thus, the more negative the strain, the better the LV ...
Santos Paulo Cjl - - 2014
Polymorphisms in the LPA gene were associated with coronary artery disease (CAD). However, there are differences in the allelic frequencies, Lp(a) levels, and significant association with CAD according to ethnic groups. In this scenario, the main aim of this study was to assess the influence of the LPA polymorphisms on ...
Meijs Loek Petrus Bartholomeus LP Catharina - - 2014
Ischemic preconditioning is a form of intrinsic cardioprotection where an episode of sublethal ischemia protects against subsequent episodes of ischemia. Identifying a clinical biomarker of preconditioning could have important clinical implications and prior work has focused on the electrocardiographic (ECG) ST-segment. However, the electrophysiology biomarker of preconditioning is increased action ...
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