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Results 251 - 300 of 3215
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Dangas George D - - 2014
A periprocedural myocardial infarction, defined as the advent of new Q-waves or a creatine kinase-MB elevation >83 normal has been previously validated as predictive of subsequent mortality. We examined the effects of using this clinically relevant definition of periprocedural myocardial infarction instead of the original protocol definition on outcomes in ...
Smith Brandon M BM Division of Pediatric Cardiology, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan. Electronic address: - - 2014
Late gadolinium enhancement (LGE) on cardiovascular magnetic resonance imaging is associated with adverse events in adults with hypertrophic cardiomyopathy (HC). However, limited data exist on the extent and clinical significance of LGE in the pediatric population. In 30 patients (aged 14.1 ± 3.2 years) with clinically diagnosed HC who underwent cardiovascular ...
Wasfy Jason H JH From the Cardiology Division (J.H.W., C.O'B., R.W.Y.), Department of Medicine (J.H.W., C.O'B., R.W.Y., J.B.S.), and Laboratory of Computer Science (A.H.Z., J.L.), Massachusetts General Hospital, Harvard Medical School, Boston; Saint Luke's Mid America Heart Institute/UMKC, Kansas City, MO (K.F.K., J.A.S.); Department of Biostatistics, Harvard School of Public Health, Boston, MA (K.Z., S.-L.T.N.); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (L.M.); and Harvard Clinical Research Institute, Boston, MA (L.M., - - 2014
Rehospitalization within 30 days after an admission for percutaneous coronary intervention (PCI) is common, costly, and a future target for Medicare penalties. Causes of readmission after PCI are largely unknown. To illuminate the causes of PCI readmissions, patients with PCI readmitted within 30 days of discharge between 2007 and 2011 ...
Gianstefani Silvia S Department of Cardiology, King's College Hospital, Denmark Hill, London, United - - 2014
The aim of this study was to define the incidence of left ventricular thrombus (LVT) and its predictors in the contemporary era of primary percutaneous intervention (pPCI) and contrast echocardiography. We retrospectively analyzed 1,059 patients presenting with ST-elevation myocardial infarction (STEMI) to our tertiary cardiac center and treated with pPCI. ...
Meredith Ian T IT MonashHeart, Monash Health, Monash Medical Centre, Clayton, Victoria, Australia. Electronic address: - - 2014
In the randomized PLATINUM trial, the PROMUS Element platinum-chromium everolimus-eluting stent (PtCr-EES; Boston Scientific, Natick, Massachusetts) was noninferior to the XIENCE V cobalt-chromium everolimus-eluting stent (CoCr-EES; Boston Scientific and Abbott Vascular, Santa Clara, California) for the primary end point of 1-year target lesion failure. This study reports the 3-year outcomes. ...
Machado Carina C aDepartment of Cardiology, Santa Cruz Hospital, Lisbon bDepartment of Cardiology, Divino Espírito Santo Hospital, Ponta Delgada, - - 2014
Randomized trials and registries have shown that drug-eluting stents (DES) have an overall better performance than bare-metal stents in patients treated in the setting of both stent thrombosis (ST) and non-ST-segment elevation acute coronary syndromes, mainly by reducing restenosis. Whether or not the use of newer second-generation devices (vs. first-generation ...
Cona Marlein Miranda MM Department of Imaging and Pathology, Faculty of Medicine, Biomedical Sciences Group , KU Leuven, Leuven , Belgium - - 2014
Abstract Objectives: We determined whether sodium cholate (NaCh) could act as a solubilizing agent for the necrosis avid iodine-123-labeled hypericin ((123)I-Hyp) and investigated biodistribution and targetability of this formulation in rabbits with acute myocardial infarction (AMI). Materials and methods: Solubility of radioiodinated hypericin/hypericin (Hyp) in NaCh solutions was evaluated by ...
Abate Elena E Department of Cardiology, Leiden University Medical Center, Leiden, The - - 2014
The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) ...
Kristensen Steen D SD Department of Cardiology, Aarhus University Hospital, Brendstrupgaardsvej 100, Skejby, DK-8200 Aarhus N, - - 2014
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. A cross-sectional descriptive study ...
Zencirci Ertuğrul E Department of Cardiology, Acibadem Maslak Hospital, Buyukdere C. 40 Maslak/Sarıyer, 34457, Istanbul, Turkey, - - 2014
The relationship between epicardial adipose tissue (EAT) and coronary artery disease has been predominantly demonstrated in the last two decades. The aim of this study was to investigate the predictive value of EAT thickness on ST-segment resolution that reflects myocardial reperfusion in patients undergoing primary percutaneous coronary intervention (pPCI) for ...
Carlsson Marcus M Department of Clinical Physiology and Nuclear Medicine, Lund University Hospital, Lund University, Lund, - - 2014
Adenosine is widely used as a vasodilator agent in myocardial perfusion imaging. Caffeine inhibits the effect, but the time of caffeine abstinence needed is under discussion and varies from 12 to 24 h. Therefore, our aim was to examine whether the time of caffeine abstinence affects the hyperaemic response using quantification ...
Kocka Viktor V Cardiocenter, Third Faculty of Medicine, Charles University in Prague, University Hospital Kralovske Vinohrady, Srobarova 60, 100 34 Prague 10, Czech - - 2014
Bioresorbable vascular scaffolds (BVSs) have been studied in chronic coronary artery disease, but not in acute ST-segment elevation myocardial infarction (STEMI). This prospective multicentre study analysed the feasibility and safety of BVS implantation during primary percutaneous coronary intervention (p-PCI) in STEMI. Bioresorbable vascular scaffold implantation became the default strategy for ...
Erkol Ayhan A Department of Cardiology, Kocaeli Derince Education and Research Hospital, İbni Sina Bulvarı, Derince, Kocaeli, Turkey, - - 2014
D-dimer is a final product of fibrin degradation and gives an indirect estimation of the thrombotic burden. We aimed to investigate the value of plasma D-dimer levels on admission in predicting no-reflow after primary percutaneous coronary intervention (p-PCI) and long-term prognosis in patients with ST segment elevation myocardial infarction (STEMI). ...
Esen Zencirci Aycan A Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Training and Research Hospital. - - 2014
Clinical outcomes of patients with myocardial infarction are primarily determined by successful restoration of myocardial reperfusion and the severity of coronary atherosclerosis. The purpose of this study was to investigate the predictive value of Gensini score on ST-segment resolution (STR) in patients undergoing primary percutaneous coronary intervention (pPCI) for acute ...
Luca Botto Giovanni G S. Anna Hospital, Como, Italy. Electronic address: - - 2014
Several studies have shown that unnecessary right ventricular pacing has detrimental effects. We evaluated whether minimization of ventricular pacing improves clinical outcomes compared with standard dual chamber pacing (DDD) in patients referred for pacemaker or implantable cardioverter defibrillator (ICD) replacement. In a randomized single-blinded multi-center international trial we compared DDD ...
Naya Masanao M NonInvasive Cardiovascular Imaging Program, Departments of Medicine (Cardiology) and Radiology, Brigham and Women's Hospital, Boston, - - 2014
Myocardial perfusion imaging has limited sensitivity for the detection of high-risk coronary artery disease (CAD). We tested the hypothesis that a normal coronary flow reserve (CFR) would be helpful for excluding the presence of high-risk CAD on angiography. We studied 290 consecutive patients undergoing (82)Rb PET within 180 d of ...
Yadav Mayank M Cardiovascular Research Foundation, New York, NY; New York-Presbyterian Hospital/ Columbia University Medical Center, New York, - - 2014
Objective. We sought to investigate the relationship between the SYNTAX score (SS) and stent thrombosis (ST) in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) undergoing percutaneous coronary intervention (PCI). Background. The relationship between the SS and ST is undetermined. Methods. We stratified 2,627 patients undergoing PCI in the ACUITY ...
Ojji D B DB 1] Cardiology Unit, Department of Medicine, University of Abuja Teaching Hospital, Abuja, Nigeria [2] Faculty of Health Sciences, Department of Medicine, Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, Cape Town, South - - 2014
Soluble ST2 is a biomarker of cardiomyocyte stretch that is useful in the diagnosis and prognosis of coronary artery disease. Its role in the field of hypertension and hypertensive heart failure (HHF) has not yet been well investigated. We studied the effect of left ventricular remodelling on the concentration of ...
Park Hyo Eun - - 2014
Metabolic syndrome (MetS) is related with left ventricular diastolic dysfunction (LVDD) and poor cardiovascular outcome. Epicardial adipose tissue (EAT) thickness, measured by echocardiography, is increased in subjects with MetS. However, the association of EAT with LV diastolic function has not been evaluated in subjects with MetS. In this retrospective study, ...
Aburawi Elhadi H EH Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, United Arab Emirates; Departments of Pediatric Cardiology, Skåne University Hospital, Lund University, Sweden. Electronic address: - - 2014
To assess the possible effect of a stiff right ventricle on the coronary flow (CF) in patients with post-operative Tetralogy of Fallot (TOF). Right ventricular restrictive physiology i.e. forward flow during atrial contraction (RVRP), is characteristic to many patients with post-operative TOF. A total of 34 patients with TOF anatomically ...
Dieplinger Benjamin B Department of Laboratory Medicine, Konventhospital Barmherzige Brueder Linz, Linz, - - 2014
sST2 has emerged as a strong prognostic biomarker in patients with heart failure and myocardial infarction. The aim of this study was to evaluate the long-term prognostic value of sST2 in patients with stable coronary artery disease (CAD).METHODS: sST2 plasma concentrations were measured in 1345 patients with stable CAD referred ...
Antonio Manari M Interventional Cardiology Unit, Azienda Ospedaliera S. Maria Nuova - IRCCS, Reggio - - 2014
Objectives. To examine the differences in cardiac outcomes for patients with ST-elevation myocardial infarction (STEMI) and multivessel disease (MVD) as a function of whether they underwent culprit-only primary percutaneous coronary intervention (PPCI) or multivessel PCI, either during PPCI or as a staged procedure. Background. MVD occurs in about 40% of ...
Francia Pietro P Cardiology, Department of Clinical and Molecular Medicine, University Sapienza, Rome, - - 2014
Myocardial extracellular matrix remodelling provides electrical heterogeneity entailing ventricular tachycardia/fibrillation (VT/VF) in heart failure (HF) patients. Osteopontin (OPN) and Galectin-3 (Gal-3) are fibrosis markers and may reflect the extension of the arrhythmogenic substrate. We assessed whether plasma OPN and Gal-3 predict the risk of sustained VT/VF in a cohort of ...
Ikonomidis Ignatios I 2nd Cardiology Department, National and Kapodistrian University of Athens, Medical School, Attikon Hospital, Athens, Greece. Electronic address: - - 2014
Reduced coronary velocity flow reserve (CFR) is associated with poor outcome in patients with cardiovascular disease. We investigated whether CFR is associated with tissue ischemia and acidosis, impaired myocardial deformation and adverse outcome in patients with septic shock. In 70 mechanically-ventilated patients with septic shock, we examined: a) S' and ...
Yamamoto Hideya H Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, - - 2014
At least two-thirds of cases of acute coronary syndrome are caused by disruption of an atherosclerotic plaque. The natural history of individual plaques is unknown and needs to be established. The Plaque Registration and Evaluation Detected In Computed Tomography (PREDICT) registry is a prospective, multicenter, longitudinal, observational registry. This registry ...
Du Bulin B Department of Nuclear Medicine, The First Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, 110001, - - 2014
Patients with severe coronary artery disease (CAD) may present impaired mitochondrial function to enhance (99m)Tc-sestamibi (MIBI) washout from ischemic myocardium. In this study, we aimed to study the MIBI washout rate (WR) between patients with three-vessel CAD (3V-CAD) confirmed by invasive coronary angiography and healthy normal volunteers (HNV) to evaluate ...
Wang Jen-Yu JY Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, New Taipei City, - - 2014
This nationwide population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES) and mortality rates for acute myocardial infarction (AMI) in Taiwan. A population-based follow-up study included 23,568 patients diagnosed with AMI from 2004 to 2008. Each patient was monitored for 2years, or until their death, whichever came ...
Arroyo Diego - - 2014
Second-generation everolimus-eluting stents (EES) and third generation biolimus-eluting stents (BES) have been shown to be superior to first-generation paclitaxel-eluting stents (PES) and second-generation sirolimus-eluting stents (SES). However, neointimal proliferation and very late stent thrombosis is still an unresolved issue of drug-eluting stent (DES) implantation overall. The AbsorbTM (Abbott Vascular, Abbott ...
Naji Peyman P Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
Significant myxomatous mitral regurgitation (MR) leads to progressive left ventricular (LV) decline, resulting in congestive heart failure (CHF) and death. Such patients benefit from mitral valve (MV) surgery. Exercise echocardiography (ExEc) aids in risk stratification and helps decide surgical timing. We sought to assess predictors of outcomes in such patients ...
Chen Yequn Y 1First Affiliated Hospital of Shantou University Medical College, Shantou, - - 2014
-Non-O type of ABO blood group has been associated with predisposition to coronary heart disease. It is believed that this association is partly mediated by increased cholesterol levels in non-O type individuals. In this study, we sought to estimate the mediation effect size. -In a group of individuals (n=6476) undergoing ...
Diletti Roberto R Thoraxcenter, Erasmus MC, 's-Gravendijkwal 230, 3015 CE Rotterdam, the - - 2014
We evaluated the feasibility and the acute performance of the everolimus-eluting bioresorbable vascular scaffolds (BVS) for the treatment of patients presenting with ST-segment elevation myocardial infarction (STEMI). The present investigation is a prospective, single-arm, single-centre study, reporting data after the BVS implantation in STEMI patients. Quantitative coronary angiography and optical ...
Bonaca Marc P MP TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
P2Y12 receptor antagonist therapy is recommended in addition to ASA for up to 1 year after acute coronary syndrome to reduce ischemic events. In contrast, the benefit of long-term dual antiplatelet therapy beyond 1 year remains unclear. Ticagrelor is a potent, reversibly binding P2Y12 receptor-antagonist that has been shown to ...
Harayama Nobuya N Critical Care Medicine, University Hospital, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan, - - 2014
Nifekalant is a pure potassium channel blocker that has been used to treat ventricular tachyarrhythmias since 1999 in Japan. Intravenous amiodarone was approved later than nifekalant in Japan, and it is still unclear which of the two agents is superior. The aim of this study was to compare the efficacy ...
Baars Theodor T Institute for Pathophysiology, University of Essen Medical School, Essen, - - 2014
Ischemic postconditioning (PoCo) reduces infarct size following myocardial ischemia/reperfusion. To protect, PoCo must be performed early during reperfusion, and causal cardioprotective signaling must occur then. The role of microRNA (miRNA) in PoCo is unclear. Anesthetized pigs were subjected to 60 min left anterior descending coronary artery (LAD) occlusion and 180 min reperfusion. ...
Latus Heiner - - 2014
In patients with anomalous left coronary artery from the pulmonary artery (ALCAPA) left ventricular (LV) dilatation and dysfunction evolves due to diminished myocardial perfusion caused by coronary steal phenomenon. Using late gadolinium enhanced cardiovascular magnetic resonance (LGE-CMR) imaging, myocardial scarring has been shown in ALCAPA patients late after repair, however ...
Herendael Hugo Van HV Electrophysiology Section, Cardiovascular Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, - - 2014
Monomorphic ventricular premature depolarizations (VPDs) have been found to initiate ventricular fibrillation (VF) or polymorphic ventricular tachycardia (PMVT) in patients with and without structural heart disease. To describe and characterize sites of origin of VPDs triggering VF and PMVT METHODS: The distribution of mapping confirmed VPDs, electrophysiology laboratory findings and ...
Takaoka Naoko N Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, - - 2014
Some plaques lead to ST-segment elevation myocardial infarction (STEMI), whereas others cause non-ST-segment elevation acute coronary syndrome (NSTEACS). We used angiography and intravascular ultrasound (IVUS) to investigate the difference of culprit lesion morphologies in ACS. Consecutive 158 ACS patients whose culprit lesions were imaged by preintervention IVUS were enrolled (STEMI=81; ...
De Luca Giuseppe G Division of Cardiology, "Maggiore della Carità" Hospital, Eastern Piedmont University, Novara, Italy. Electronic address: - - 2014
Prior studies have found that smokers with STEMI have lower mortality rates and a more favorable response to fibrinolytic therapy than nonsmokers, phenomenon defined as "the smoker's paradox". Still poorly explored is the impact of cigarette smoking in patients undergoing primary percutaneous coronary intervention. Aim of the current study was ...
Brunetti Natale Daniele ND 1 Department of Cardiology, University of Foggia , Foggia, Italy - - 2014
Abstract Background: Heat waves have been reported as being associated with increased rates of hospitalizations and deaths. Materials and Methods: In July 2011, a heat wave hit southern Italy. We enrolled 9,282 consecutive patients who called the Apulia (southeastern Italy) regional free public emergency medical service (EMS) "118" number (out ...
Peng Ya Guang YG State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, People's Republic of - - 2014
Prehospital delay is the most critical factor to prognosis of ST-elevation myocardial infarction (STEMI). Few study had examined a series of predictors of prehospital delay by multivariate analysis of sociodemographic and clinical characteristics, onset features, and symptom condition of STEMI in China. A total of 1088 hospitalized STEMI participants were ...
Jarman Julian W E JW Imperial College London, - - 2014
Localized rotors have been implicated in the mechanism of persistent atrial fibrillation (AF). Although regions of highest dominant frequency (DF) on spectral analysis of the left atrium (LA) have been said to identify rotors, other mechanisms such as wavefront collisions will sporadically also generate an inconsistent distribution of high DF. ...
Pennell Dudley J DJ Royal Brompton Hospital, London, United - - 2014
Transfusion-dependent patients are at risk of myocardial iron deposition. Randomized comparison data on the efficacy and safety of deferasirox for myocardial iron removal are lacking. CORDELIA was a prospective, randomized comparison of deferasirox (target dose 40mg/kg/day) vs subcutaneous deferoxamine (50-60mg/kg/day for 5-7 days/week) for myocardial iron removal in 197 beta-thalassemia ...
Citro Rodolfo R Department of Heart Sciences, Circolo Hospital and Macchi Foundation, University of Insubria, Varese, Italy; Heart Department, University Hospital San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy. Electronic address: - - 2014
To determine clinical and echocardiographic correlates of acute heart failure, cardiogenic shock and in-hospital mortality in a large cohort of tako-tsubo cardiomyopathy (TTC) patients. Despite good long-term prognosis, life-threatening complications due to hemodynamic instability can occur early in TTC patients. The study population consisted of 227 patients (66.2 ± 12.2 ...
Gardner Blake - - 2014
We and others have shown that increases in particulate air pollutant (PM) concentrations in the previous hours and days have been associated with increased risks of myocardial infarction, but little is known about the relationships between air pollution and specific subsets of myocardial infarction, such as ST-elevation myocardial infarction (STEMI) ...
Sako Edward Y EY University of Texas Health Science Center at San Antonio, San Antonio, Tex. Electronic address: - - 2014
Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) was a study of management strategies for diabetic patients with myocardial ischemia and coronary artery disease. In a 2 × 2 design, early revascularization versus medical management with or without late revascularization and insulin sensitization versus insulin provision were examined. No advantage for either ...
Tosu Aydın Rodi AR Clinic of Cardiology, Van Education and Research Hospital, Van-Turkey. - - 2014
Objective of this study was to investigate the correlation between P wave dispersion and left ventricular diastolic function, which are associated with the increased cardiovascular events in patients with dipper and non-dipper HT. Eighty sex and age matched patients with dipper and non-dipper HT, and 40 control subject were included ...
Hsiao Hao-Ming - - 2014
Longitudinal stent compression (LSC) is a new failure mode not previously observed in coronary stents. This phenomenon occurs when the physician tries to cross the deployed stent with other devices. While this phenomenon has been observed with a number of stent designs, it seems more common with the Element stent. ...
Zoroufian Arezoo A Department of Echocardiography, Tehran Heart Center, North Kargar Street, Tehran 14117 13138, Iran. - - 2014
Objectives- The purpose of this study was to investigate whether systolic mechanical dyssynchrony occurs in hypertensive patients with a normal coronary artery and a normal ejection fraction and its relationship with different degrees of left ventricular (LV) hypertrophy. Methods- A total of 125 angiographically normal coronary patients (42.4% male; mean ...
de Castro Brás Lisandra E LE UMMC, Physiology, Jackson, Mississippi, United States ; - - 2014
Aim: To evaluate the role of matrix metalloproteinase (MMP)-9 deletion on citrate synthase activity post-MI. Results: We fractionated left ventricle (LV) samples using a differential solubility-based approach. The insoluble protein fraction was analyzed by mass spectrometry, and we identified citrate synthase as a potential intracellular substrate of MMP-9 in the ...
Mozid Abdul M AM The Essex Cardiothoracic Centre, Nethermayne, Essex, SS16 5NL United Kingdom. - - 2014
We aimed to assess the impact of a non-infarct related artery (IRA) chronic total occlusion (CTO) on clinical outcomes following primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI) in a real-world cohort of patients. This is a retrospective observational study of 1435 patients treated at a large single ...
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