Search Results
Results 251 - 300 of 3237
< 1 2 3 4 5 6 7 8 9 10 11 >
Saaby Lotte L Department of Cardiology, Odense University Hospital, Odense, - - 2014
The classification of myocardial infarction into five types was introduced in 2007. The prognostic impact of this Universal definition with particular focus on type 2 myocardial infarction has not been prospectively studied in unselected hospital patients. During a one-year period all hospitalized patients having cardiac troponin I measured were considered. ...
Havranek Stepan S 1 Second Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University, Prague - Czech - - 2014
Background: The aim of our study was to analyze, in a pig model of prolonged ventricular fibrillation (VF) treated by veno-arterial extracorporeal membrane oxygenation (ECMO), the time dependent changes of VF wavelet frequency obtained from intracardial signals and its relations to return of spontaneous circulation (ROSC).Methods: 11 female pigs (50.3 ...
Distelmaier Klaus K Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria; Division of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN, - - 2014
Recent data suggest that acute coronary syndromes (ACS) and acute myocardial infarction (AMI) are characterized by an inflammatory subset of thrombosis. We have previously described the accumulation of neutrophils at the coronary culprit lesion site. In this work, we assessed the prognostic value of culprit site (CS) neutrophil accumulation on ...
Sarli B B Department of Cardiology, Kayseri Education and Research Hospital, 38010, Kayseri, Turkey, - - 2014
Preintervention thrombus burden in the infarct-related artery is an independent predictor of no-reflow and adverse outcomes in coronary artery disease. The role of D-dimers in the acute phase of ST-elevated myocardial infarction (STEMI) during primary percutaneous coronary intervention (PCI) has not been fully elucidated. We aimed to investigate the predictive ...
Korkmaz L L Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey, - - 2014
The"no-reflow" phenomenon is associated with a worse prognosis at follow-up for patients with acute ST-segment elevation myocardial infarction (STEMI). Predicting and preventing no-reflow is therefore a crucial step in improving the prognosis of STEMI patients. The purpose of this study was to investigate the association between aortic valve sclerosis (AVS) ...
Ullah Waqas W 1Cardiovascular Biomedical Research Unit, St. Bartholomew's Hospital, Barts Health NHS Trust, London, United - - 2014
-In animal studies of radiofrequency ablation, lesion sizes plateau as the maximum lesion size is reached for an ablation. Lesion parameters are not available in clinical ablations, but preclinical work suggests that these correlate with impedance drop and electrogram attenuation. Characterization of the relationship between catheter contact force (CF),ablation duration ...
Lidsky Michael E ME Department of Surgery, Duke University Medical Center, DUMC 3247, Durham, NC, 27710, USA, - - 2014
Coronary artery disease (CAD) is often considered a contraindication to hepatectomy despite a lack of data to support this practice. The purpose of this study is to evaluate the impact of CAD on postoperative outcomes in patients undergoing hepatectomy. A total of 1,206 consecutive patients undergoing hepatectomy from August 1995 ...
Okada Kazunori K Graduate School of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sapporo, 060-0812, - - 2014
Left ventricular (LV) diastolic dysfunction is often observed in healthy older subjects without structural heart disease, although its exact mechanisms have not been established. A decrease in the aorto-septal angle (ASA), an alteration of LV shape due to aortic elongation, is also frequently seen in elderly subjects. The objective of ...
Härle Tobias T Klinikum Oldenburg, Klinik für Kardiologie, Rahel-Straus-Str. 10, 26133, Oldenburg, Germany, - - 2014
Drug-eluting stents (DES) reduce the rate of in-stent restenosis (ISR) and target vessel revascularization significantly when compared with bare metal stents (BMS). Their beneficial effects have been demonstrated in patients with acute myocardial infarction also, but the use of DES in the latter population seems to be still limited in ...
Ngaage D L DL Lancashire Cardiac Centre, Blackpool Victoria Hospital, Whinney Heys Road, Blackpool, UK - - - 2014
Aim: The aim of this paper was to compare the clinical impact of the different myocardial protection strategies in coronary artery bypass grafting (CABG) patients to facilitate decision-making for use of on- or off-pump technique. Methods: Prospectively collected data for primary CABG patients between April 1, 1996 and December 30, ...
Imamura Teruhiko T Department of Cardiovascular Medicine, Graduate School of Medicine, University of - - 2014
Background: The continuous flow (CF) left ventricular assist device (LVAD) has replaced the pulsatile flow (PF) LVAD because of its advantages of better patient survival and higher quality of life. However, "late-onset right ventricular failure (RVF)" after CF LVAD implantation has emerged as an increasing concern, but little is known about ...
Plicner Dariusz D Unit of Experimental Cardiac Surgery, Cardiology and Anesthesiology, Institute of Cardiology, Jagiellonian University School of Medicine , Krakow , Poland - - 2014
Abstract Perioperative myocardial infarction (PMI) following coronary artery bypass grafting (CABG) is associated with significant morbidity and mortality. The aim of this study was to assess platelet activation and oxidative stress in the setting of PMI in patients undergoing CABG. We studied 108 consecutive patients who stopped taking low-dose aspirin ...
Gale C P CP Division of Epidemiology and Biostatistics, University of Leeds, , Leeds, - - 2014
To investigate temporal changes in survival after acute myocardial infarction (AMI) by early invasive strategy. Accelerated failure time and 6-month relative survival analyses stratified by thrombolysis or primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI) and coronary angiography for non-STEMI (NSTEMI) encompassing 583 466 patients across 247 ...
Hyvelin Jean-Marc JM From the Bracco Suisse SA, Geneva, - - 2014
The diagnosis of acute coronary syndrome remains challenging especially in patients without clear symptoms or electrocardiographic and/or biomarker features. A hallmark of ischemia/reperfusion is activation of endothelial cells leading to altered expression of molecular markers, including selectins. In this context, we aimed to validate the value of ultrasound molecular imaging ...
Jamil-Copley Shahnaz S Department of cardiac electrophysiology, St.Mary's and Hammersmith Hospitals, Imperial College NHS Healthcare Trust and Imperial College London, United - - 2014
Localising the origin of outflow tract ventricular tachycardias (OTVT) is hampered by lack of accuracy of ECG algorithms and infrequent spontaneous premature ventricular complexes (PVC) during electrophysiological studies (EPS). This study aims to prospectively assess the performance of non-invasive electrocardiographic mapping (ECM) in the pre-/peri-procedural localisation of OTVT origin to ...
Pyxaras Stylianos A SA Cardiovascular Center Aalst, OLV Clinic, Aalst, - - 2014
Aim. To assess ACEF (age, creatinine, and ejection fraction) and Clinical SYNTAX (CSS) score in the risk stratification of patients with heavily calcified stenosis undergoing rotational atherectomy with stent implantation (rota-stenting). Methods and results. ACEF and CSS were calculated in 221 consecutive patients with stable angina undergoing rota-stenting. Mean age ...
Nishimura Masato M Cardiovascular Division, Toujinkai Hospital, Kyoto, - - 2014
Background/Aims: The assessment of myocardial fatty acid metabolism impairment by single-photon emission computed tomography (SPECT) using (123)I-β-methyliodophenyl-pentadecanoic acid (BMIPP) might predict the risk of cardiac death in hemodialysis patients. We investigated the potential of oral nicorandil to improve myocardial fatty acid metabolism after percutaneous coronary intervention (PCI) in this population. ...
Lupón Josep J Heart Failure Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain ; Department of Medicine, Autonomous University of Barcelona, Barcelona, - - 2014
A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF). A novel calculator (BCN Bio-HF calculator) incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch), high-sensitivity cardiac troponin T (hs-cTnT, a marker of ...
Dangas George D - - 2014
A periprocedural myocardial infarction, defined as the advent of new Q-waves or a creatine kinase-MB elevation >83 normal has been previously validated as predictive of subsequent mortality. We examined the effects of using this clinically relevant definition of periprocedural myocardial infarction instead of the original protocol definition on outcomes in ...
Smith Brandon M BM Division of Pediatric Cardiology, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan. Electronic address: - - 2014
Late gadolinium enhancement (LGE) on cardiovascular magnetic resonance imaging is associated with adverse events in adults with hypertrophic cardiomyopathy (HC). However, limited data exist on the extent and clinical significance of LGE in the pediatric population. In 30 patients (aged 14.1 ± 3.2 years) with clinically diagnosed HC who underwent cardiovascular ...
Wasfy Jason H JH From the Cardiology Division (J.H.W., C.O'B., R.W.Y.), Department of Medicine (J.H.W., C.O'B., R.W.Y., J.B.S.), and Laboratory of Computer Science (A.H.Z., J.L.), Massachusetts General Hospital, Harvard Medical School, Boston; Saint Luke's Mid America Heart Institute/UMKC, Kansas City, MO (K.F.K., J.A.S.); Department of Biostatistics, Harvard School of Public Health, Boston, MA (K.Z., S.-L.T.N.); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (L.M.); and Harvard Clinical Research Institute, Boston, MA (L.M., - - 2014
Rehospitalization within 30 days after an admission for percutaneous coronary intervention (PCI) is common, costly, and a future target for Medicare penalties. Causes of readmission after PCI are largely unknown. To illuminate the causes of PCI readmissions, patients with PCI readmitted within 30 days of discharge between 2007 and 2011 ...
Gianstefani Silvia S Department of Cardiology, King's College Hospital, Denmark Hill, London, United - - 2014
The aim of this study was to define the incidence of left ventricular thrombus (LVT) and its predictors in the contemporary era of primary percutaneous intervention (pPCI) and contrast echocardiography. We retrospectively analyzed 1,059 patients presenting with ST-elevation myocardial infarction (STEMI) to our tertiary cardiac center and treated with pPCI. ...
Meredith Ian T IT MonashHeart, Monash Health, Monash Medical Centre, Clayton, Victoria, Australia. Electronic address: - - 2014
In the randomized PLATINUM trial, the PROMUS Element platinum-chromium everolimus-eluting stent (PtCr-EES; Boston Scientific, Natick, Massachusetts) was noninferior to the XIENCE V cobalt-chromium everolimus-eluting stent (CoCr-EES; Boston Scientific and Abbott Vascular, Santa Clara, California) for the primary end point of 1-year target lesion failure. This study reports the 3-year outcomes. ...
Machado Carina C aDepartment of Cardiology, Santa Cruz Hospital, Lisbon bDepartment of Cardiology, Divino Espírito Santo Hospital, Ponta Delgada, - - 2014
Randomized trials and registries have shown that drug-eluting stents (DES) have an overall better performance than bare-metal stents in patients treated in the setting of both stent thrombosis (ST) and non-ST-segment elevation acute coronary syndromes, mainly by reducing restenosis. Whether or not the use of newer second-generation devices (vs. first-generation ...
Cona Marlein Miranda MM Department of Imaging and Pathology, Faculty of Medicine, Biomedical Sciences Group , KU Leuven, Leuven , Belgium - - 2014
Abstract Objectives: We determined whether sodium cholate (NaCh) could act as a solubilizing agent for the necrosis avid iodine-123-labeled hypericin ((123)I-Hyp) and investigated biodistribution and targetability of this formulation in rabbits with acute myocardial infarction (AMI). Materials and methods: Solubility of radioiodinated hypericin/hypericin (Hyp) in NaCh solutions was evaluated by ...
Abate Elena E Department of Cardiology, Leiden University Medical Center, Leiden, The - - 2014
The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) ...
Kristensen Steen D SD Department of Cardiology, Aarhus University Hospital, Brendstrupgaardsvej 100, Skejby, DK-8200 Aarhus N, - - 2014
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. A cross-sectional descriptive study ...
Zencirci Ertuğrul E Department of Cardiology, Acibadem Maslak Hospital, Buyukdere C. 40 Maslak/Sarıyer, 34457, Istanbul, Turkey, - - 2014
The relationship between epicardial adipose tissue (EAT) and coronary artery disease has been predominantly demonstrated in the last two decades. The aim of this study was to investigate the predictive value of EAT thickness on ST-segment resolution that reflects myocardial reperfusion in patients undergoing primary percutaneous coronary intervention (pPCI) for ...
Carlsson Marcus M Department of Clinical Physiology and Nuclear Medicine, Lund University Hospital, Lund University, Lund, - - 2014
Adenosine is widely used as a vasodilator agent in myocardial perfusion imaging. Caffeine inhibits the effect, but the time of caffeine abstinence needed is under discussion and varies from 12 to 24 h. Therefore, our aim was to examine whether the time of caffeine abstinence affects the hyperaemic response using quantification ...
Kocka Viktor V Cardiocenter, Third Faculty of Medicine, Charles University in Prague, University Hospital Kralovske Vinohrady, Srobarova 60, 100 34 Prague 10, Czech - - 2014
Bioresorbable vascular scaffolds (BVSs) have been studied in chronic coronary artery disease, but not in acute ST-segment elevation myocardial infarction (STEMI). This prospective multicentre study analysed the feasibility and safety of BVS implantation during primary percutaneous coronary intervention (p-PCI) in STEMI. Bioresorbable vascular scaffold implantation became the default strategy for ...
Erkol Ayhan A Department of Cardiology, Kocaeli Derince Education and Research Hospital, İbni Sina Bulvarı, Derince, Kocaeli, Turkey, - - 2014
D-dimer is a final product of fibrin degradation and gives an indirect estimation of the thrombotic burden. We aimed to investigate the value of plasma D-dimer levels on admission in predicting no-reflow after primary percutaneous coronary intervention (p-PCI) and long-term prognosis in patients with ST segment elevation myocardial infarction (STEMI). ...
Esen Zencirci Aycan A Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Training and Research Hospital. - - 2014
Clinical outcomes of patients with myocardial infarction are primarily determined by successful restoration of myocardial reperfusion and the severity of coronary atherosclerosis. The purpose of this study was to investigate the predictive value of Gensini score on ST-segment resolution (STR) in patients undergoing primary percutaneous coronary intervention (pPCI) for acute ...
Luca Botto Giovanni G S. Anna Hospital, Como, Italy. Electronic address: - - 2014
Several studies have shown that unnecessary right ventricular pacing has detrimental effects. We evaluated whether minimization of ventricular pacing improves clinical outcomes compared with standard dual chamber pacing (DDD) in patients referred for pacemaker or implantable cardioverter defibrillator (ICD) replacement. In a randomized single-blinded multi-center international trial we compared DDD ...
Naya Masanao M NonInvasive Cardiovascular Imaging Program, Departments of Medicine (Cardiology) and Radiology, Brigham and Women's Hospital, Boston, - - 2014
Myocardial perfusion imaging has limited sensitivity for the detection of high-risk coronary artery disease (CAD). We tested the hypothesis that a normal coronary flow reserve (CFR) would be helpful for excluding the presence of high-risk CAD on angiography. We studied 290 consecutive patients undergoing (82)Rb PET within 180 d of ...
Yadav Mayank M Cardiovascular Research Foundation, New York, NY; New York-Presbyterian Hospital/ Columbia University Medical Center, New York, - - 2014
Objective. We sought to investigate the relationship between the SYNTAX score (SS) and stent thrombosis (ST) in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) undergoing percutaneous coronary intervention (PCI). Background. The relationship between the SS and ST is undetermined. Methods. We stratified 2,627 patients undergoing PCI in the ACUITY ...
Ojji D B DB 1] Cardiology Unit, Department of Medicine, University of Abuja Teaching Hospital, Abuja, Nigeria [2] Faculty of Health Sciences, Department of Medicine, Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, Cape Town, South - - 2014
Soluble ST2 is a biomarker of cardiomyocyte stretch that is useful in the diagnosis and prognosis of coronary artery disease. Its role in the field of hypertension and hypertensive heart failure (HHF) has not yet been well investigated. We studied the effect of left ventricular remodelling on the concentration of ...
Park Hyo Eun - - 2014
Metabolic syndrome (MetS) is related with left ventricular diastolic dysfunction (LVDD) and poor cardiovascular outcome. Epicardial adipose tissue (EAT) thickness, measured by echocardiography, is increased in subjects with MetS. However, the association of EAT with LV diastolic function has not been evaluated in subjects with MetS. In this retrospective study, ...
Aburawi Elhadi H EH Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, United Arab Emirates; Departments of Pediatric Cardiology, Skåne University Hospital, Lund University, Sweden. Electronic address: - - 2014
To assess the possible effect of a stiff right ventricle on the coronary flow (CF) in patients with post-operative Tetralogy of Fallot (TOF). Right ventricular restrictive physiology i.e. forward flow during atrial contraction (RVRP), is characteristic to many patients with post-operative TOF. A total of 34 patients with TOF anatomically ...
Dieplinger Benjamin B Department of Laboratory Medicine, Konventhospital Barmherzige Brueder Linz, Linz, - - 2014
sST2 has emerged as a strong prognostic biomarker in patients with heart failure and myocardial infarction. The aim of this study was to evaluate the long-term prognostic value of sST2 in patients with stable coronary artery disease (CAD).METHODS: sST2 plasma concentrations were measured in 1345 patients with stable CAD referred ...
Antonio Manari M Interventional Cardiology Unit, Azienda Ospedaliera S. Maria Nuova - IRCCS, Reggio - - 2014
Objectives. To examine the differences in cardiac outcomes for patients with ST-elevation myocardial infarction (STEMI) and multivessel disease (MVD) as a function of whether they underwent culprit-only primary percutaneous coronary intervention (PPCI) or multivessel PCI, either during PPCI or as a staged procedure. Background. MVD occurs in about 40% of ...
Francia Pietro P Cardiology, Department of Clinical and Molecular Medicine, University Sapienza, Rome, - - 2014
Myocardial extracellular matrix remodelling provides electrical heterogeneity entailing ventricular tachycardia/fibrillation (VT/VF) in heart failure (HF) patients. Osteopontin (OPN) and Galectin-3 (Gal-3) are fibrosis markers and may reflect the extension of the arrhythmogenic substrate. We assessed whether plasma OPN and Gal-3 predict the risk of sustained VT/VF in a cohort of ...
Ikonomidis Ignatios I 2nd Cardiology Department, National and Kapodistrian University of Athens, Medical School, Attikon Hospital, Athens, Greece. Electronic address: - - 2014
Reduced coronary velocity flow reserve (CFR) is associated with poor outcome in patients with cardiovascular disease. We investigated whether CFR is associated with tissue ischemia and acidosis, impaired myocardial deformation and adverse outcome in patients with septic shock. In 70 mechanically-ventilated patients with septic shock, we examined: a) S' and ...
Yamamoto Hideya H Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, - - 2014
At least two-thirds of cases of acute coronary syndrome are caused by disruption of an atherosclerotic plaque. The natural history of individual plaques is unknown and needs to be established. The Plaque Registration and Evaluation Detected In Computed Tomography (PREDICT) registry is a prospective, multicenter, longitudinal, observational registry. This registry ...
Du Bulin B Department of Nuclear Medicine, The First Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, 110001, - - 2014
Patients with severe coronary artery disease (CAD) may present impaired mitochondrial function to enhance (99m)Tc-sestamibi (MIBI) washout from ischemic myocardium. In this study, we aimed to study the MIBI washout rate (WR) between patients with three-vessel CAD (3V-CAD) confirmed by invasive coronary angiography and healthy normal volunteers (HNV) to evaluate ...
Wang Jen-Yu JY Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, New Taipei City, - - 2014
This nationwide population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES) and mortality rates for acute myocardial infarction (AMI) in Taiwan. A population-based follow-up study included 23,568 patients diagnosed with AMI from 2004 to 2008. Each patient was monitored for 2years, or until their death, whichever came ...
Arroyo Diego - - 2014
Second-generation everolimus-eluting stents (EES) and third generation biolimus-eluting stents (BES) have been shown to be superior to first-generation paclitaxel-eluting stents (PES) and second-generation sirolimus-eluting stents (SES). However, neointimal proliferation and very late stent thrombosis is still an unresolved issue of drug-eluting stent (DES) implantation overall. The AbsorbTM (Abbott Vascular, Abbott ...
Naji Peyman P Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
Significant myxomatous mitral regurgitation (MR) leads to progressive left ventricular (LV) decline, resulting in congestive heart failure (CHF) and death. Such patients benefit from mitral valve (MV) surgery. Exercise echocardiography (ExEc) aids in risk stratification and helps decide surgical timing. We sought to assess predictors of outcomes in such patients ...
Chen Yequn Y 1First Affiliated Hospital of Shantou University Medical College, Shantou, - - 2014
-Non-O type of ABO blood group has been associated with predisposition to coronary heart disease. It is believed that this association is partly mediated by increased cholesterol levels in non-O type individuals. In this study, we sought to estimate the mediation effect size. -In a group of individuals (n=6476) undergoing ...
Diletti Roberto R Thoraxcenter, Erasmus MC, 's-Gravendijkwal 230, 3015 CE Rotterdam, the - - 2014
We evaluated the feasibility and the acute performance of the everolimus-eluting bioresorbable vascular scaffolds (BVS) for the treatment of patients presenting with ST-segment elevation myocardial infarction (STEMI). The present investigation is a prospective, single-arm, single-centre study, reporting data after the BVS implantation in STEMI patients. Quantitative coronary angiography and optical ...
Bonaca Marc P MP TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
P2Y12 receptor antagonist therapy is recommended in addition to ASA for up to 1 year after acute coronary syndrome to reduce ischemic events. In contrast, the benefit of long-term dual antiplatelet therapy beyond 1 year remains unclear. Ticagrelor is a potent, reversibly binding P2Y12 receptor-antagonist that has been shown to ...
< 1 2 3 4 5 6 7 8 9 10 11 >