Search Results
Results 201 - 250 of 3214
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Hyler Stefan S The Intervention Centre, Rikshospitalet, Oslo University Hospital, Oslo, - - 2014
Preservation of left ventricular (LV) function is crucial for a beneficial outcome in high-risk patients undergoing cardiac surgery. The present study evaluated a motion sensor (accelerometer) for continuous monitoring of LV performance during changes in global and regional LV function. In 11 pigs, an accelerometer was sutured to the epicardium ...
Rhee June-Wha JW Department of Medicine, Stanford University Medical Center, Stanford, - - 2014
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular events following acute coronary syndrome (ACS). The underlying pathobiology and optimal treatments for this population continue to be evaluated. Patients with CKD will receive fewer evidence-based therapies and experience high rates of adverse cardiovascular events in both the ...
Kim Sung Eun SE Department of Internal Medicine, Kangdong Sacred Heart Hospital, Seoul, - - 2014
The non-invasive differentiation of ischemic and non-ischemic acute heart failure (AHF) not resulting from acute myocardial infarction is difficult and has therapeutic and prognostic implications. The aim of this study was to assess whether plasma B-type natriuretic peptide (BNP) can identify ischemic etiology in patients with stage 4-5 chronic kidney ...
Arini Pedro David PD Argentine Institute of Mathematics, 'Alberto P. Calderón' (CONICET), Saavedra 15, C1083ACA, Buenos Aires, Argentina, - - 2014
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices ...
Poller Wolfram C WC Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie (CCM), Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany, - - 2014
Cardiac resynchronization therapy (CRT) is an effective treatment for a large subgroup of chronic heart failure patients. Various attempts to improve the high non-responder rate of 30 % by preoperative asynchrony assessment have failed. We hypothesized that superior response to CRT is correlated with greater acute reduction of asynchrony and that ...
Akin I I Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Deutschland, - - 2014
Drug-eluting stents (DES) have substantially reduced target vessel revascularization (TVR) after percutaneous coronary interventions. Risk factors for clinical events need to be redefined with this treatment option. In the prospective DES.DE registry, baseline clinical and angiographic characteristics as well as in-hospital and follow-up events were recorded for all enrolled patients. ...
Lamberts Morten M Copenhagen University Hospital Gentofte, Hellerup, - - 2014
Optimal long-term antithrombotic treatment of patients with coexisting atrial fibrillation (AF) and stable coronary artery disease (CAD) is unresolved and commonly a single antiplatelet agent is added to oral anticoagulation. We investigated the effectiveness and safety of adding antiplatelet therapy to vitamin K antagonist (VKA) in AF patents with stable ...
Erlinge David D Department of Cardiology, Lund University, 221 85, Lund, Sweden. Electronic address: - - 2014
Hypothermia has been reported to reduce infarct size (IS) in patients with ST segment elevation myocardial infarction (STEMI). We aimed to confirm the cardioprotective effects of hypothermia using a combination of cold saline and endovascular cooling. In a multi-center study, 120 patients with STEMI (<6 hours) planned to undergo percutaneous ...
Khan Abdur Rahman AR Division of Cardiovascular Medicine, Department of Internal Medicine, University of Toledo Medical Center, Toledo, OH, - - 2014
The objective of this study is to evaluate the prevalence, geometric patterns, and factors associated with left ventricular remodeling in patients with renal artery stenosis (RAS). Demographic, clinical, and echocardiographic data were assessed in 77 patients with RAS prior to endovascular stenting. The left ventricular mass index (LVMI) and relative ...
Jiang Cuihua C Laboratory of Translational Medicine, Jiangsu Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu Province, - - 2014
The aim of this study was to investigate the necrosis avid agent hypericin as a potential indicator for determination of myocardial infarction (MI). Male Sprague-Dawley rats (n=30) weighing 350±20 g were subjected to acute reperfused MI. Animals were divided into 4 groups (n=6), in which hypericin was intravenously injected at ...
Lupi-Herrera Eulo E Eulo Lupi-Herrera, The American British Cowdray Medical Center I.A.P., Mexico City 14080, - - 2014
To investigate the impact of primary reperfusion therapy (RT) on early and late mortality in acute right ventricular infarction (RVI). RVI patients (n = 679) were prospectively classified as without right ventricular failure (RVF) (class A, n = 425, 64%), with RVF (class B, n = 158, 24%) or with ...
Fayssoil Abdallah A Réanimation médicale, Hôpital Raymond Poincaré (AP-HP), Université de Versailles SQY, 104 boulevard Raymond Poincaré, 92380, Garches, France, - - 2014
Sarcoglycanopathies are autosomic recessive muscular dystrophies, secondary to mutations of the sarcoglycan complex. Heart can be involved in sarcoglycanopathies. We sought to analyse left ventricular function in patients with alpha-sarcoglycanopathy and gamma-sarcoglycanopathy. We conducted a retrospective study that aimed to analyse clinical and echocardiographic data of patients with sarcoglycanopathies. Our ...
Nishi Hiroyuki H Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, - - 2014
We describe the first clinical experiences in Japan with the HeartWare ventricular assist device (HVAD: HeartWare Inc., Miami Lakes, FL, USA) in patients awaiting heart transplantation. Nine patients (6 males, 3 females; mean 33.5 ± 7.8 years; New York Heart Association class III or IV) received the HVAD as a bridge to transplantation ...
MÅ‚ynarska Agnieszka - - 2014
INTRODUCTION There is no research that evaluated the tendency to reduce the traditional cardiovascular risk in patients with different values of coronary artery calcium score (CACS). The aim of the study was to evaluate the influence of the CACS examination for the reduction of the global cardiovascular risk. PATIENTS AND METHODS Research ...
Martins Raphael P RP University of Michigan, Ann Arbor, - - 2014
Little is known about the mechanisms underlying the transition from paroxysmal to persistent atrial fibrillation (AF). In an ovine model of long-standing persistent AF (LS-PAF) we tested the hypothesis that the rate of electrical and/or structural remodeling, assessed by dominant frequency (DF) changes, determines the time at which AF becomes ...
Sugumar Hariharan H Department of Cardiology, Austin Hospital, Melbourne, Victoria, - - 2014
Comorbidities, such as diabetes, affect revascularization strategy for coronary disease. We sought to determine if the degree of renal impairment affected long-term mortality after percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) in patients with multi-vessel coronary disease (MVD). 8970 patients with MVD undergoing revascularization between 2004 ...
Saraf S S Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, UK, - - 2014
This study aimed at evaluating the outcome of Biolimus eluting stent (BES) implantation in the treatment of chronic total coronary occlusions (CTO). We identified patients who underwent successful angioplasty for a CTO lesion with ≥1 BES between June 2008 and March 2012. All patients were followed up for major adverse ...
Mogabgab Owen O VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, - - 2014
To assess the impact of viscosity on angioplasty balloon deflation times. Lower contrast viscosity could result in more rapid coronary balloon deflation times. We performed a bench comparison of coronary balloon deflation times using 2 contrast agents with different viscosity (ioxaglate and iodixanol), 3 contrast dilutions, and 2 inflation syringe ...
Kluz Krystyna K Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech - - 2014
Pre-infarction unstable angina pectoris (UAP) can be considered ischemic preconditioning. The aim of this study was to compare short and long term outcomes in patients with or without pre-infarction UAP and ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). 593 patients with STEMI (388 without and 205 ...
Sun Dian-Min DM aPeking Union Medical College, Chinese Academy of Medical Science bFuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing cTEDA International Cardiovascular Hospital, Tianjin, China dCardiac Signaling Center of USC, MUSC & Clemson University, Charleston, South Carolina eMetrowest Medical Center, Framingham, Massachusetts, - - 2014
New-onset postoperative atrial fibrillation (POAF) is one of the most common complications occurring in 10-40% of patients after coronary artery bypass graft (CABG) surgery. Recent studies suggest that dysmetabolism may contribute to the pathogenesis of atrial fibrillation; however, the putative mechanism in patients undergoing CABG surgery is unknown. Peroxisome proliferator-activated ...
Carol Antoni A Cardiology Service, Hospital Universitari Germans Trias i Pujol, Badalona. Electronic address: - - 2014
Autopsy studies show that dynamic coronary thrombosis leads to infarction. We studied intracoronary thrombus age in ST-segment elevation myocardial infarction (STEMI) and its relationship with clinical presentation and epicardial reperfusion grade. Intracoronary thrombectomy was performed in 131 STEMI patients within 24 h after symptom onset, and material sufficient for pathological ...
Wang Yun Y From Qualidigm, Wethersfield (Y.W., M.L.M., N.R.V., T.P.M., M.M.P., J.M.F., S.-Y.H., D.G.), the Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington (M.L.M.), and the Center for Outcomes Research and Evaluation, Yale-New Haven Hospital (Y.W., H.M.K.), the Department of Health Policy and Management, Yale School of Public Health (H.M.K.), and the Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program (H.M.K.) and the Section of General Internal Medicine (T.P.M., D.G., H.M.K.), Department of Internal Medicine, Yale University School of Medicine, New Haven - all in Connecticut; the Department of Biostatistics, Harvard School of Public Health (Y.W.), and the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School (J.M.F.) - all in Boston; and the Agency for Healthcare Research and Quality, Department of Health and Human Services, Rockville (N.E., J.B.), and the Centers for Medicare and Medicaid Services, Department of Health and Human Services, Baltimore (R.E.K., N.S.) - both in - - 2014
Changes in adverse-event rates among Medicare patients with common medical conditions and conditions requiring surgery remain largely unknown. We used Medicare Patient Safety Monitoring System data abstracted from medical records on 21 adverse events in patients hospitalized in the United States between 2005 and 2011 for acute myocardial infarction, congestive ...
Goto Shinya S Department of Medicine (Cardiology), Tokai University School of Medicine, Isehara, Kanagawa, - - 2014
Patients with acute coronary syndrome (ACS) usually receive acetylsalicylic acid plus an adenosine diphosphate (ADP) receptor inhibitor to reduce the long-term risk of recurrent events. However, patients receiving standard antiplatelet prophylaxis still face a substantial risk of recurrent events. Strategies involving 3 antithrombotic agents with different modes of action have ...
Hübinette Clara C Department of Medicine, Karolinska Institutet, 171 77 Stockholm, - - 2014
Cardiac resynchronization therapy (CRT) and primary prophylactic implantable cardioverter-defibrillators (ICDs) are underutilized in heart failure (HF). This may originate from an unawareness of device benefits and indications among physicians responsible for HF care and referral. We aimed to describe the awareness of indications for device therapy in a generalized sample ...
Chung Sheng-Chia SC Farr Institute of Health Informatics Research at UCL Partners, University College London, London, - - 2014
International research for acute myocardial infarction lacks comparisons of whole health systems. We assessed time trends for care and outcomes in Sweden and the UK. We used data from national registries on consecutive patients registered between 2004 and 2010 in all hospitals providing care for acute coronary syndrome in Sweden ...
García-Alvarez Ana A University of Barcelona, Barcelona, - - 2014
Few studies have addressed the additional value of B-type natriuretic peptide (BNP) on risk stratification in non-ST-elevation acute coronary syndrome (NSTE-ACS). We aimed to evaluate whether BNP levels provide additional improvement on discrimination and reclassification of patients at risk of mortality during admission and follow up after a NSTE-ACS. BNP ...
Suncion Viky Y VY University of Miami Miller School of - - 2014
Transendocardial Stem Cell Injection (TESI) with mesenchymal stem cells improves remodeling in chronic ischemic cardiomyopathy, but the impact of the injection site remains unknown. To address whether TESI exerts its effects at the site of injection only or also in remote areas, we hypothesized that segmental myocardial scar and segmental ...
Russo Juan J JJ Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, , Toronto, Ontario, - - 2014
We evaluated the efficacy and safety of an early invasive strategy post-fibrinolysis in relation to glycoprotein (GP) IIb/IIIa inhibitor use. The Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI) randomised 1059 ST elevation myocardial infarction patients to an early invasive strategy or ...
Hao Kiyotaka K Department of Cardiovascular Medicine, Tohoku University Graduate School of - - 2014
Background: Although emergency care of acute myocardial infarction (AMI) could theoretically be improved through improved patient delay, this notion remains to be confirmed. Additionally, the influence of large earthquakes on the emergency care of AMI cases remains to be elucidated. The Great East Japan Earthquake (March 11, 2011) has enabled us ...
Park Duk-Woo DW Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Periprocedural myocardial infarction (MI) can be induced by several angiographic mechanisms. However, there are limited data on whether these mechanisms differentially affect clinical outcomes. The purpose of our study was to investigate the impact of periprocedural MI on mortality according to the underlying angiographic mechanisms after drug-eluting stent (DES) implantation. ...
Imamura Tsuyoshi T Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
It has not been fully determined whether non-high-density lipoprotein cholesterol (non-HDLC) levels are involved in vascular events, especially stroke, in general Asian populations. We evaluated the association between non-HDLC levels and the risk of type-specific cardiovascular disease in a prospective cohort study in Japan. A total of 2452 community-dwelling Japanese ...
Saaby Lotte L Department of Cardiology, Odense University Hospital, Odense, - - 2014
The classification of myocardial infarction into five types was introduced in 2007. The prognostic impact of this Universal definition with particular focus on type 2 myocardial infarction has not been prospectively studied in unselected hospital patients. During a one-year period all hospitalized patients having cardiac troponin I measured were considered. ...
Havranek Stepan S 1 Second Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University, Prague - Czech - - 2014
Background: The aim of our study was to analyze, in a pig model of prolonged ventricular fibrillation (VF) treated by veno-arterial extracorporeal membrane oxygenation (ECMO), the time dependent changes of VF wavelet frequency obtained from intracardial signals and its relations to return of spontaneous circulation (ROSC).Methods: 11 female pigs (50.3 ...
Distelmaier Klaus K Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria; Division of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN, - - 2014
Recent data suggest that acute coronary syndromes (ACS) and acute myocardial infarction (AMI) are characterized by an inflammatory subset of thrombosis. We have previously described the accumulation of neutrophils at the coronary culprit lesion site. In this work, we assessed the prognostic value of culprit site (CS) neutrophil accumulation on ...
Sarli B B Department of Cardiology, Kayseri Education and Research Hospital, 38010, Kayseri, Turkey, - - 2014
Preintervention thrombus burden in the infarct-related artery is an independent predictor of no-reflow and adverse outcomes in coronary artery disease. The role of D-dimers in the acute phase of ST-elevated myocardial infarction (STEMI) during primary percutaneous coronary intervention (PCI) has not been fully elucidated. We aimed to investigate the predictive ...
Korkmaz L L Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey, - - 2014
The"no-reflow" phenomenon is associated with a worse prognosis at follow-up for patients with acute ST-segment elevation myocardial infarction (STEMI). Predicting and preventing no-reflow is therefore a crucial step in improving the prognosis of STEMI patients. The purpose of this study was to investigate the association between aortic valve sclerosis (AVS) ...
Ullah Waqas W 1Cardiovascular Biomedical Research Unit, St. Bartholomew's Hospital, Barts Health NHS Trust, London, United - - 2014
-In animal studies of radiofrequency ablation, lesion sizes plateau as the maximum lesion size is reached for an ablation. Lesion parameters are not available in clinical ablations, but preclinical work suggests that these correlate with impedance drop and electrogram attenuation. Characterization of the relationship between catheter contact force (CF),ablation duration ...
Lidsky Michael E ME Department of Surgery, Duke University Medical Center, DUMC 3247, Durham, NC, 27710, USA, - - 2014
Coronary artery disease (CAD) is often considered a contraindication to hepatectomy despite a lack of data to support this practice. The purpose of this study is to evaluate the impact of CAD on postoperative outcomes in patients undergoing hepatectomy. A total of 1,206 consecutive patients undergoing hepatectomy from August 1995 ...
Okada Kazunori K Graduate School of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sapporo, 060-0812, - - 2014
Left ventricular (LV) diastolic dysfunction is often observed in healthy older subjects without structural heart disease, although its exact mechanisms have not been established. A decrease in the aorto-septal angle (ASA), an alteration of LV shape due to aortic elongation, is also frequently seen in elderly subjects. The objective of ...
Härle Tobias T Klinikum Oldenburg, Klinik für Kardiologie, Rahel-Straus-Str. 10, 26133, Oldenburg, Germany, - - 2014
Drug-eluting stents (DES) reduce the rate of in-stent restenosis (ISR) and target vessel revascularization significantly when compared with bare metal stents (BMS). Their beneficial effects have been demonstrated in patients with acute myocardial infarction also, but the use of DES in the latter population seems to be still limited in ...
Ngaage D L DL Lancashire Cardiac Centre, Blackpool Victoria Hospital, Whinney Heys Road, Blackpool, UK - - - 2014
Aim: The aim of this paper was to compare the clinical impact of the different myocardial protection strategies in coronary artery bypass grafting (CABG) patients to facilitate decision-making for use of on- or off-pump technique. Methods: Prospectively collected data for primary CABG patients between April 1, 1996 and December 30, ...
Imamura Teruhiko T Department of Cardiovascular Medicine, Graduate School of Medicine, University of - - 2014
Background: The continuous flow (CF) left ventricular assist device (LVAD) has replaced the pulsatile flow (PF) LVAD because of its advantages of better patient survival and higher quality of life. However, "late-onset right ventricular failure (RVF)" after CF LVAD implantation has emerged as an increasing concern, but little is known about ...
Plicner Dariusz D Unit of Experimental Cardiac Surgery, Cardiology and Anesthesiology, Institute of Cardiology, Jagiellonian University School of Medicine , Krakow , Poland - - 2014
Abstract Perioperative myocardial infarction (PMI) following coronary artery bypass grafting (CABG) is associated with significant morbidity and mortality. The aim of this study was to assess platelet activation and oxidative stress in the setting of PMI in patients undergoing CABG. We studied 108 consecutive patients who stopped taking low-dose aspirin ...
Gale C P CP Division of Epidemiology and Biostatistics, University of Leeds, , Leeds, - - 2014
To investigate temporal changes in survival after acute myocardial infarction (AMI) by early invasive strategy. Accelerated failure time and 6-month relative survival analyses stratified by thrombolysis or primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI) and coronary angiography for non-STEMI (NSTEMI) encompassing 583 466 patients across 247 ...
Hyvelin Jean-Marc JM From the Bracco Suisse SA, Geneva, - - 2014
The diagnosis of acute coronary syndrome remains challenging especially in patients without clear symptoms or electrocardiographic and/or biomarker features. A hallmark of ischemia/reperfusion is activation of endothelial cells leading to altered expression of molecular markers, including selectins. In this context, we aimed to validate the value of ultrasound molecular imaging ...
Jamil-Copley Shahnaz S Department of cardiac electrophysiology, St.Mary's and Hammersmith Hospitals, Imperial College NHS Healthcare Trust and Imperial College London, United - - 2014
Localising the origin of outflow tract ventricular tachycardias (OTVT) is hampered by lack of accuracy of ECG algorithms and infrequent spontaneous premature ventricular complexes (PVC) during electrophysiological studies (EPS). This study aims to prospectively assess the performance of non-invasive electrocardiographic mapping (ECM) in the pre-/peri-procedural localisation of OTVT origin to ...
Pyxaras Stylianos A SA Cardiovascular Center Aalst, OLV Clinic, Aalst, - - 2014
Aim. To assess ACEF (age, creatinine, and ejection fraction) and Clinical SYNTAX (CSS) score in the risk stratification of patients with heavily calcified stenosis undergoing rotational atherectomy with stent implantation (rota-stenting). Methods and results. ACEF and CSS were calculated in 221 consecutive patients with stable angina undergoing rota-stenting. Mean age ...
Nishimura Masato M Cardiovascular Division, Toujinkai Hospital, Kyoto, - - 2014
Background/Aims: The assessment of myocardial fatty acid metabolism impairment by single-photon emission computed tomography (SPECT) using (123)I-β-methyliodophenyl-pentadecanoic acid (BMIPP) might predict the risk of cardiac death in hemodialysis patients. We investigated the potential of oral nicorandil to improve myocardial fatty acid metabolism after percutaneous coronary intervention (PCI) in this population. ...
Lupón Josep J Heart Failure Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain ; Department of Medicine, Autonomous University of Barcelona, Barcelona, - - 2014
A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF). A novel calculator (BCN Bio-HF calculator) incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch), high-sensitivity cardiac troponin T (hs-cTnT, a marker of ...
Dangas George D - - 2014
A periprocedural myocardial infarction, defined as the advent of new Q-waves or a creatine kinase-MB elevation >83 normal has been previously validated as predictive of subsequent mortality. We examined the effects of using this clinically relevant definition of periprocedural myocardial infarction instead of the original protocol definition on outcomes in ...
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