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Results 201 - 250 of 3230
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Mujarić Ekrema E 1Department of Internal Medicine, Cantonal Hospital Zenica, 2Department of Internal Medicine, General Hospital Tešanj, 3Department of Anesthesiology and Intensive Care, Cantonal Hospital Zenica, 4Department of Surgery, Cantonal Hospital Zenica, 5Department of Laboratory Diagnostics, University Clinic Tuzla, 6Department of Gantroenterohepatology, University Clinical Center, Sarajevo; Bosnia and - - 2014
Aim To analyze a change of level of nautriuretic peptide (NT pro- BNP) caused by stress distension of myocardial wall in cases of acute myocardial infarction (AIM), as a possible predictor of early heart failure. Methods Patients with myocardial infarction were followed up. Standard clinical and laboratory examination, including NT ...
Huang Shao-Hong SH Department of Cardiothoracic Surgery, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, China, - - 2014
Intracellular calcium overload is a key factor for myocardial ischemia reperfusion injury (IR). However, there was no report for interstitial calcium concentration dynamics. We investigated the interstitial calcium dynamics in rat myocardial IR model in vivo. A microdialysis system was involved, and the time delay of the system and recovery ...
Brenner Roman R Division of Cardiology, Kantonsspital St. Gallen, Rorschacherstrasse 95, CH-9007 St. Gallen, - - 2014
Aim: Inflammatory processes may contribute to myocardial ischemia/reperfusion injury after myocardial infarction (MI). We aimed to evaluate the predictive value of complement factor concentrations for the occurrence of post-MI left ventricular (LV) dysfunction. Patients & methods: Fifty-five patients with acute MI were included. Complement factors and CRP were assessed at ...
Dores Hélder H 1 Hospital de Santa Cruz, Lisbon, Portugal ; 2 Hospital de Faro, Faro, Portugal ; 3 Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal ; 4 Hospital de São Bernardo, Setúbal, - - 2014
Although the proven efficacy of evidence-based therapy in patients with cardiovascular diseases, the recommendations are not always instituted. We aimed to analyse the compliance of non-ST-elevation acute coronary syndrome (NSTE-ACS) patients with treatment guidelines and to assess the impact of these measures in hospital death during the index hospitalization. All ...
Abbasnezhad Mohsen M Department of Cardiology, Tabriz University of Medical Sciences, Tabriz, IR - - 2014
Chest pain is one of the most common causes of the admission to the emergency departments. It, however, can be due to numerous diseases some of which are life threatening. In the current study, we evaluated the prognostic value of TIMI (Thrombolysis in Myocardial Infarction) and Modified TIMI risk scores ...
Bellam Naveen N Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Road NE, Room 529, Atlanta, GA, 30324, - - 2014
An impaired chronotropic response to exercise is an accepted risk marker but the relationship between heart rate reserve (HRR) with pharmacologic stress is less well-established. The primary aim of this analysis was to evaluate the prognostic significance of HRR in patients undergoing rest/stress myocardial perfusion positron emission tomography (PET) in ...
Liebetrau Christoph C Department of Cardiology, Kerckhoff Heart and Thorax Center, , Bad Nauheim, - - 2014
To determine the release kinetics of different biomarkers with potential as novel early ischaemic biomarkers in patients with acute coronary syndrome (ACS); it is difficult to establish the detailed release kinetics in patients with acute myocardial infarction (AMI). We analysed the release kinetics of soluble fms-like tyrosine kinase (sFlt-1), ischaemia ...
De Servi Stefano S aCardiovascular Department, AO 'Ospedale Civile', Legnano bDivision of Cardiology, Manzoni Hospital, Lecco cDivision of Cardiology, Misericordia e Dolce Hospital, Prato dDivision of Cardiology, AO 'Villa Scassi', Genova eDivision of Cardiology, Ospedali Riuniti, Treviglio fCardiology Unit, Spedali Civili, Brescia gDivision of Cardiology, St Antonio Abate Hospital, Gallarate hDivision of Cardiology, Desio Hospital, Desio iDivision of Cardiology, Terni Hospital, Terni jLaboratory Unit, AO 'Ospedale Civile' di Legnano, - - 2014
Serum cystatin C (Cys-C), a good marker of renal function, predicts prognosis in non-ST-elevation acute coronary syndromes (NSTE-ACS). However, no data are available on the time course of Cys-C values after discharge. In this study, Cys-C was measured during admission (ACS sample) and 6 weeks after discharge, and was correlated ...
Jochmann Nicoline - - 2014
Experimental data suggests that exclusive heart rate reduction with ivabradine is associated with the amelioration of the endothelial function. Since it is presently unknown whether this also applies to humans, the aim of this pilot study was to investigate whether heart rate reduction with ivabradine modulates the endothelial function in ...
Taniwaki Masanori M Bern University Hospital, Bern, - - 2014
To investigate 4-year outcomes and predictors of repeat revascularization in patients treated with Resolute™ zotarolimus-eluting stent (R-ZES) and XIENCE V™ everolimus-eluting stent (EES) in the RESOLUTE All Comers trial. Data on long-term outcomes of new generation drug-eluting stents are limited, and predictors of repeat revascularization due to restenosis and/or progression ...
Figueras Jaume J Unitat Coronària, Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Electronic address: - - 2014
Occurrence of moderate-to-severe pericardial effusion (PE; ≥10 mm), cardiac tamponade (CT), and sudden electromechanical dissociation (EMD) was investigated in 4,361 patients with ST-elevation myocardial infarction from 1993 to 2011 in 3 different periods: 1993 to 2000 (n: 1,488); 2001 to 2008 (n: 1,844); and 2009 to 2011 (n: 1,014). Their predictors, ...
Moss Travis J TJ Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, - - 2014
Because alcohol septal ablation (ASA) for the treatment of symptomatic hypertrophic cardiomyopathy (HC) with left ventricular (LV) outflow tract (LVOT) obstruction results in a myocardial infarct of up to 10% of ventricular mass, LV systolic function could decline over time. We evaluated LV function during longitudinal follow-up in a cohort ...
Goebel Björn B 1st Department of Medicine, Division of Cardiology, University Hospital of Jena, Erlanger Allee 101, 07740, Jena, Germany, - - 2014
The aim of this prospective study was to assess the value of speckle tracking echocardiographic (2D-STE) parameters to predict response to heart failure therapy in patients with dilated cardiomyopathy (DCM). Eighty-seven patients (mean age 51 ± 13 years) with DCM, defined as ejection fraction (EF) <45 %, left ventricular (LV) end-diastolic diameter >112 % of ...
Lupi Alessandro A Hospital Cardiology, "Maggiore della Carità" Hospital, Novara, - - 2014
Objectives: to perform an updated meta-analysis comparing biodegradable (BP-DES) and durable (DP-DES) polymer drug eluting stents. Background: BP-DES have been suggested to reduce late stent thrombosis (LST) rates as compared to 1(st) generation DP-DES. Recently, 2(nd) generation DP-DES have replaced older DES, but comparisons of these stents with BP-DES has ...
Hyler Stefan S The Intervention Centre, Rikshospitalet, Oslo University Hospital, Oslo, - - 2014
Preservation of left ventricular (LV) function is crucial for a beneficial outcome in high-risk patients undergoing cardiac surgery. The present study evaluated a motion sensor (accelerometer) for continuous monitoring of LV performance during changes in global and regional LV function. In 11 pigs, an accelerometer was sutured to the epicardium ...
Rhee June-Wha JW Department of Medicine, Stanford University Medical Center, Stanford, - - 2014
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular events following acute coronary syndrome (ACS). The underlying pathobiology and optimal treatments for this population continue to be evaluated. Patients with CKD will receive fewer evidence-based therapies and experience high rates of adverse cardiovascular events in both the ...
Kim Sung Eun SE Department of Internal Medicine, Kangdong Sacred Heart Hospital, Seoul, - - 2014
The non-invasive differentiation of ischemic and non-ischemic acute heart failure (AHF) not resulting from acute myocardial infarction is difficult and has therapeutic and prognostic implications. The aim of this study was to assess whether plasma B-type natriuretic peptide (BNP) can identify ischemic etiology in patients with stage 4-5 chronic kidney ...
Arini Pedro David PD Argentine Institute of Mathematics, 'Alberto P. Calderón' (CONICET), Saavedra 15, C1083ACA, Buenos Aires, Argentina, - - 2014
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices ...
Poller Wolfram C WC Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie (CCM), Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany, - - 2014
Cardiac resynchronization therapy (CRT) is an effective treatment for a large subgroup of chronic heart failure patients. Various attempts to improve the high non-responder rate of 30 % by preoperative asynchrony assessment have failed. We hypothesized that superior response to CRT is correlated with greater acute reduction of asynchrony and that ...
Akin I I Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Deutschland, - - 2014
Drug-eluting stents (DES) have substantially reduced target vessel revascularization (TVR) after percutaneous coronary interventions. Risk factors for clinical events need to be redefined with this treatment option. In the prospective DES.DE registry, baseline clinical and angiographic characteristics as well as in-hospital and follow-up events were recorded for all enrolled patients. ...
Lamberts Morten M Copenhagen University Hospital Gentofte, Hellerup, - - 2014
Optimal long-term antithrombotic treatment of patients with coexisting atrial fibrillation (AF) and stable coronary artery disease (CAD) is unresolved and commonly a single antiplatelet agent is added to oral anticoagulation. We investigated the effectiveness and safety of adding antiplatelet therapy to vitamin K antagonist (VKA) in AF patents with stable ...
Erlinge David D Department of Cardiology, Lund University, 221 85, Lund, Sweden. Electronic address: - - 2014
Hypothermia has been reported to reduce infarct size (IS) in patients with ST segment elevation myocardial infarction (STEMI). We aimed to confirm the cardioprotective effects of hypothermia using a combination of cold saline and endovascular cooling. In a multi-center study, 120 patients with STEMI (<6 hours) planned to undergo percutaneous ...
Khan Abdur Rahman AR Division of Cardiovascular Medicine, Department of Internal Medicine, University of Toledo Medical Center, Toledo, OH, - - 2014
The objective of this study is to evaluate the prevalence, geometric patterns, and factors associated with left ventricular remodeling in patients with renal artery stenosis (RAS). Demographic, clinical, and echocardiographic data were assessed in 77 patients with RAS prior to endovascular stenting. The left ventricular mass index (LVMI) and relative ...
Jiang Cuihua C Laboratory of Translational Medicine, Jiangsu Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu Province, - - 2014
The aim of this study was to investigate the necrosis avid agent hypericin as a potential indicator for determination of myocardial infarction (MI). Male Sprague-Dawley rats (n=30) weighing 350±20 g were subjected to acute reperfused MI. Animals were divided into 4 groups (n=6), in which hypericin was intravenously injected at ...
Lupi-Herrera Eulo E Eulo Lupi-Herrera, The American British Cowdray Medical Center I.A.P., Mexico City 14080, - - 2014
To investigate the impact of primary reperfusion therapy (RT) on early and late mortality in acute right ventricular infarction (RVI). RVI patients (n = 679) were prospectively classified as without right ventricular failure (RVF) (class A, n = 425, 64%), with RVF (class B, n = 158, 24%) or with ...
Fayssoil Abdallah A Réanimation médicale, Hôpital Raymond Poincaré (AP-HP), Université de Versailles SQY, 104 boulevard Raymond Poincaré, 92380, Garches, France, - - 2014
Sarcoglycanopathies are autosomic recessive muscular dystrophies, secondary to mutations of the sarcoglycan complex. Heart can be involved in sarcoglycanopathies. We sought to analyse left ventricular function in patients with alpha-sarcoglycanopathy and gamma-sarcoglycanopathy. We conducted a retrospective study that aimed to analyse clinical and echocardiographic data of patients with sarcoglycanopathies. Our ...
Nishi Hiroyuki H Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, - - 2014
We describe the first clinical experiences in Japan with the HeartWare ventricular assist device (HVAD: HeartWare Inc., Miami Lakes, FL, USA) in patients awaiting heart transplantation. Nine patients (6 males, 3 females; mean 33.5 ± 7.8 years; New York Heart Association class III or IV) received the HVAD as a bridge to transplantation ...
Młynarska Agnieszka - - 2014
INTRODUCTION There is no research that evaluated the tendency to reduce the traditional cardiovascular risk in patients with different values of coronary artery calcium score (CACS). The aim of the study was to evaluate the influence of the CACS examination for the reduction of the global cardiovascular risk. PATIENTS AND METHODS Research ...
Martins Raphael P RP University of Michigan, Ann Arbor, - - 2014
Little is known about the mechanisms underlying the transition from paroxysmal to persistent atrial fibrillation (AF). In an ovine model of long-standing persistent AF (LS-PAF) we tested the hypothesis that the rate of electrical and/or structural remodeling, assessed by dominant frequency (DF) changes, determines the time at which AF becomes ...
Sugumar Hariharan H Department of Cardiology, Austin Hospital, Melbourne, Victoria, - - 2014
Comorbidities, such as diabetes, affect revascularization strategy for coronary disease. We sought to determine if the degree of renal impairment affected long-term mortality after percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) in patients with multi-vessel coronary disease (MVD). 8970 patients with MVD undergoing revascularization between 2004 ...
Saraf S S Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, UK, - - 2014
This study aimed at evaluating the outcome of Biolimus eluting stent (BES) implantation in the treatment of chronic total coronary occlusions (CTO). We identified patients who underwent successful angioplasty for a CTO lesion with ≥1 BES between June 2008 and March 2012. All patients were followed up for major adverse ...
Mogabgab Owen O VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, - - 2014
To assess the impact of viscosity on angioplasty balloon deflation times. Lower contrast viscosity could result in more rapid coronary balloon deflation times. We performed a bench comparison of coronary balloon deflation times using 2 contrast agents with different viscosity (ioxaglate and iodixanol), 3 contrast dilutions, and 2 inflation syringe ...
Kluz Krystyna K Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech - - 2014
Pre-infarction unstable angina pectoris (UAP) can be considered ischemic preconditioning. The aim of this study was to compare short and long term outcomes in patients with or without pre-infarction UAP and ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). 593 patients with STEMI (388 without and 205 ...
Sun Dian-Min DM aPeking Union Medical College, Chinese Academy of Medical Science bFuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing cTEDA International Cardiovascular Hospital, Tianjin, China dCardiac Signaling Center of USC, MUSC & Clemson University, Charleston, South Carolina eMetrowest Medical Center, Framingham, Massachusetts, - - 2014
New-onset postoperative atrial fibrillation (POAF) is one of the most common complications occurring in 10-40% of patients after coronary artery bypass graft (CABG) surgery. Recent studies suggest that dysmetabolism may contribute to the pathogenesis of atrial fibrillation; however, the putative mechanism in patients undergoing CABG surgery is unknown. Peroxisome proliferator-activated ...
Carol Antoni A Cardiology Service, Hospital Universitari Germans Trias i Pujol, Badalona. Electronic address: - - 2014
Autopsy studies show that dynamic coronary thrombosis leads to infarction. We studied intracoronary thrombus age in ST-segment elevation myocardial infarction (STEMI) and its relationship with clinical presentation and epicardial reperfusion grade. Intracoronary thrombectomy was performed in 131 STEMI patients within 24 h after symptom onset, and material sufficient for pathological ...
Wang Yun Y From Qualidigm, Wethersfield (Y.W., M.L.M., N.R.V., T.P.M., M.M.P., J.M.F., S.-Y.H., D.G.), the Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington (M.L.M.), and the Center for Outcomes Research and Evaluation, Yale-New Haven Hospital (Y.W., H.M.K.), the Department of Health Policy and Management, Yale School of Public Health (H.M.K.), and the Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program (H.M.K.) and the Section of General Internal Medicine (T.P.M., D.G., H.M.K.), Department of Internal Medicine, Yale University School of Medicine, New Haven - all in Connecticut; the Department of Biostatistics, Harvard School of Public Health (Y.W.), and the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School (J.M.F.) - all in Boston; and the Agency for Healthcare Research and Quality, Department of Health and Human Services, Rockville (N.E., J.B.), and the Centers for Medicare and Medicaid Services, Department of Health and Human Services, Baltimore (R.E.K., N.S.) - both in - - 2014
Changes in adverse-event rates among Medicare patients with common medical conditions and conditions requiring surgery remain largely unknown. We used Medicare Patient Safety Monitoring System data abstracted from medical records on 21 adverse events in patients hospitalized in the United States between 2005 and 2011 for acute myocardial infarction, congestive ...
Goto Shinya S Department of Medicine (Cardiology), Tokai University School of Medicine, Isehara, Kanagawa, - - 2014
Patients with acute coronary syndrome (ACS) usually receive acetylsalicylic acid plus an adenosine diphosphate (ADP) receptor inhibitor to reduce the long-term risk of recurrent events. However, patients receiving standard antiplatelet prophylaxis still face a substantial risk of recurrent events. Strategies involving 3 antithrombotic agents with different modes of action have ...
Hübinette Clara C Department of Medicine, Karolinska Institutet, 171 77 Stockholm, - - 2014
Cardiac resynchronization therapy (CRT) and primary prophylactic implantable cardioverter-defibrillators (ICDs) are underutilized in heart failure (HF). This may originate from an unawareness of device benefits and indications among physicians responsible for HF care and referral. We aimed to describe the awareness of indications for device therapy in a generalized sample ...
Chung Sheng-Chia SC Farr Institute of Health Informatics Research at UCL Partners, University College London, London, - - 2014
International research for acute myocardial infarction lacks comparisons of whole health systems. We assessed time trends for care and outcomes in Sweden and the UK. We used data from national registries on consecutive patients registered between 2004 and 2010 in all hospitals providing care for acute coronary syndrome in Sweden ...
García-Alvarez Ana A University of Barcelona, Barcelona, - - 2014
Few studies have addressed the additional value of B-type natriuretic peptide (BNP) on risk stratification in non-ST-elevation acute coronary syndrome (NSTE-ACS). We aimed to evaluate whether BNP levels provide additional improvement on discrimination and reclassification of patients at risk of mortality during admission and follow up after a NSTE-ACS. BNP ...
Suncion Viky Y VY University of Miami Miller School of - - 2014
Transendocardial Stem Cell Injection (TESI) with mesenchymal stem cells improves remodeling in chronic ischemic cardiomyopathy, but the impact of the injection site remains unknown. To address whether TESI exerts its effects at the site of injection only or also in remote areas, we hypothesized that segmental myocardial scar and segmental ...
Russo Juan J JJ Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, , Toronto, Ontario, - - 2014
We evaluated the efficacy and safety of an early invasive strategy post-fibrinolysis in relation to glycoprotein (GP) IIb/IIIa inhibitor use. The Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI) randomised 1059 ST elevation myocardial infarction patients to an early invasive strategy or ...
Hao Kiyotaka K Department of Cardiovascular Medicine, Tohoku University Graduate School of - - 2014
Background: Although emergency care of acute myocardial infarction (AMI) could theoretically be improved through improved patient delay, this notion remains to be confirmed. Additionally, the influence of large earthquakes on the emergency care of AMI cases remains to be elucidated. The Great East Japan Earthquake (March 11, 2011) has enabled us ...
Park Duk-Woo DW Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Periprocedural myocardial infarction (MI) can be induced by several angiographic mechanisms. However, there are limited data on whether these mechanisms differentially affect clinical outcomes. The purpose of our study was to investigate the impact of periprocedural MI on mortality according to the underlying angiographic mechanisms after drug-eluting stent (DES) implantation. ...
Imamura Tsuyoshi T Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
It has not been fully determined whether non-high-density lipoprotein cholesterol (non-HDLC) levels are involved in vascular events, especially stroke, in general Asian populations. We evaluated the association between non-HDLC levels and the risk of type-specific cardiovascular disease in a prospective cohort study in Japan. A total of 2452 community-dwelling Japanese ...
Saaby Lotte L Department of Cardiology, Odense University Hospital, Odense, - - 2014
The classification of myocardial infarction into five types was introduced in 2007. The prognostic impact of this Universal definition with particular focus on type 2 myocardial infarction has not been prospectively studied in unselected hospital patients. During a one-year period all hospitalized patients having cardiac troponin I measured were considered. ...
Havranek Stepan S 1 Second Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University, Prague - Czech - - 2014
Background: The aim of our study was to analyze, in a pig model of prolonged ventricular fibrillation (VF) treated by veno-arterial extracorporeal membrane oxygenation (ECMO), the time dependent changes of VF wavelet frequency obtained from intracardial signals and its relations to return of spontaneous circulation (ROSC).Methods: 11 female pigs (50.3 ...
Distelmaier Klaus K Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria; Division of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN, - - 2014
Recent data suggest that acute coronary syndromes (ACS) and acute myocardial infarction (AMI) are characterized by an inflammatory subset of thrombosis. We have previously described the accumulation of neutrophils at the coronary culprit lesion site. In this work, we assessed the prognostic value of culprit site (CS) neutrophil accumulation on ...
Sarli B B Department of Cardiology, Kayseri Education and Research Hospital, 38010, Kayseri, Turkey, - - 2014
Preintervention thrombus burden in the infarct-related artery is an independent predictor of no-reflow and adverse outcomes in coronary artery disease. The role of D-dimers in the acute phase of ST-elevated myocardial infarction (STEMI) during primary percutaneous coronary intervention (PCI) has not been fully elucidated. We aimed to investigate the predictive ...
Korkmaz L L Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey, - - 2014
The"no-reflow" phenomenon is associated with a worse prognosis at follow-up for patients with acute ST-segment elevation myocardial infarction (STEMI). Predicting and preventing no-reflow is therefore a crucial step in improving the prognosis of STEMI patients. The purpose of this study was to investigate the association between aortic valve sclerosis (AVS) ...
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