Search Results
Results 151 - 200 of 3844
1 2 3 4 5 6 7 8 9 10 >
Yuan Fei F Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, - - 2014
Drug-eluting stents (DES) with durable polymer have significantly reduced restenosis and target vessel revascularization compared with bare metal stents. Durable polymer has been linked with persistent inflammation of vessel wall and delayed endothelial healing that may increase the risk of late and very late stent thrombosis. This study sought to ...
Cortese Bernardo B Interventional Cardiology, A.O. Fatebenefratelli Milano, Milano, Italy. Electronic address: - - 2014
The risk of acute kidney injury (AKI) is a major issue after percutaneous coronary interventions (PCIs), especially in the setting of ST-elevation myocardial infarction. Preliminary data from large retrospective registries seem to show a reduction of AKI when a transradial (TR) approach for PCI is adopted. Little is known about ...
Khoo Valerie V National University Hospital Cardiac Department, Level 3, Main Building, National University Hospital, 5, Lower Kent Ridge Road, Singapore. - - 2014
We aimed to determine the incidence and predictors of side-branch compromise (SBC) in patients who underwent primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). Little data exist on SBC in AMI patients, especially in the drug-eluting stent era. We recruited 174 patients who underwent primary PCI over a ...
Bonios Michael J MJ Third Cardiology Department, Medical School, University of Athens, Athens, Greece Drs. Bonios and Kaladaridou contributed equally to this - - 2014
Left ventricular (LV) remodeling after acute myocardial infarction (AMI) is related to increased morbidity and mortality. The aim of the present study was to examine whether LV deformational and torsional parameters can predict LV remodeling in patients with AMI. Forty-two patients (age 57 ± 14 years) presenting with an anterior ...
Chen Xiaorong X 1 Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China ; 2 Department of Radiology, Jinhua Municipal Central Hospital, Jinhua Hospital of Zhejiang University, Jinhua 321000, - - 2014
The purpose of the study was to investigate the influence of late gadolinium enhancement (LGE) on the diastolic volume recovery of left ventricle in patients with hypertrophic cardiomyopathy (HCM). Twenty-four HCM patients were studied through report-card 4.0. The presence or absence of late gadolinium enhancement was recorded according to a ...
Iwano Hiroyuki H Division of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi, - - 2014
The effect of diastolic dysfunction (DD) on the timing of left ventricular (LV) diastolic longitudinal and circumferential expansion and their load dependence is not known. This study evaluated the timing of the peak early diastolic LV inflow velocity (E), mitral annular velocity (e'), and longitudinal and circumferential global strain rates ...
Andersson Charlotte C Framingham Heart Study, Mt Wayte Avenue 73, Suite 2, Framingham, MA 01702-5827, USA; Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, 801 Massachusetts Avenue, Suite 470, Boston, MA 02118, USA; Department of Cardiology, Gentofte Hospital, Niels Andersens vej 65, Hellerup 2900, Denmark. Electronic address: - - 2014
Heart failure with preserved ejection fraction (HFPEF) is a common condition, and the prevalence is projected to increase further. Studies differ in the reported incidence and mortality associated with this condition, although there is agreement that between a third and one-half of all patients with heart failure have HFPEF. Although ...
Guerchicoff Alejandra A Cardiovascular Research Foundation, New York, New - - 2014
Our aim was to study the impact of delay from symptom onset to first coronary device on infarct size and clinical outcomes at 30 days and 1 year in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention. Longer delay from symptom onset to reperfusion has been ...
Plakht Ygal Y Nursing Research Unit, Soroka University Medical Center, Beer-Sheva, Israel; Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Electronic address: - - 2014
Cardiovascular diseases are the leading cause of death in elderly people. Over the past decades medical advancements in the management of patients with acute myocardial infarction (AMI) led to improved survival and increased life expectancy. As short-term survival from AMI improves, more attention is being shifted toward understanding and improving ...
Martin Seth S SS Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, 600 N. Wolfe St, Carnegie 565-G, Baltimore, 21287 MD, USA - - 2014
High-density lipoprotein (HDL) is highly heterogeneous and the link of its subclasses to prognosis remains controversial. We aimed to rigorously examine the associations of HDL subclasses with prognosis in secondary prevention. We collaboratively analysed data from two, complementary prospective cohorts: the TRIUMPH study of 2465 acute myocardial infarction patients, and ...
Jensen Maria M MM Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, Herlev, - - 2014
Estimation of left ventricular ejection fraction (LVEF) with 99MTc-HSA equilibrium radionuclide angiography (RA) is frequently used for assessing cardiac function. The purpose of this study was to investigate the interstudy repeatability of left (LV) and right (RV) ventricular volume and ejection fraction estimations, using a cadmium-zinc-telluride (CZT) SPECT camera. Forty-six ...
Onuma Yoshinobu Y Thoraxcenter, Erasmus Medical Center, Rotterdam, The - - 2014
Aims: The reported rate of stent thrombosis (ST) after drug-eluting stent (DES) implantation varies among registries. To investigate differences in baseline characteristics and clinical outcome in European and Japanese all-comers registries, we performed a pooled analysis of patient-level data. Methods and results: The j-Cypher registry (JC) is a multicentre observational ...
Okada Munemasa M Department of Radiology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan. Electronic address: - - 2014
Sublingual nitroglycerin capsules or spray is routinely used to treat anginal attacks and to maximally dilate the epicardial coronary arteries during coronary angiography. These dilated coronary vessels have an advantage, but increased heart rates were disadvantageous for coronary computed tomography angiography (CTA). The influence of applying nitroglycerin was analyzed regarding ...
Gierula John J aLeeds Teaching Hospitals NHS Trust bDivision of Cardiovascular and Diabetes Research, Leeds Institute of Genetics, Health and Therapeutics, Multidisciplinary Cardiovascular Research Centre, University of Leeds cLeeds Institute of Health Sciences, Leeds, - - 2014
Patients with right ventricular pacemakers are at increased risk of left ventricular systolic dysfunction (LVSD). We aimed to establish the prevalence, degree and associations of LVSD in patients with long-term right ventricular pacemakers listed for pulse generator replacement (PGR). All patients listed for PGR at Leeds General Infirmary were invited ...
García-García Héctor M HM Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands; Cardialysis, Rotterdam, The Netherlands. Electronic address: - - 2014
Coronary plaque size modification, by either local (device) or systemic treatments, has been the target for many years. From ABSORB Cohort A (Absorb BVS 1.0), ABSORB Cohort B (Absorb BVS 1.1), SPIRIT FIRST (Multi-Link Vision vs. Xience V) & SPIRIT II (Xience V vs. Taxus), we calculated the total plaque ...
Sassi R R Roberto Sassi, Dipartimento di Informatica, Università degli Studi di Milano, Via Bramante 65, 26013 Crema (CR), Italy, E-mail: - - 2014
Objectives: We investigated if cardiac spatial repolarization heterogeneity might be associated with an increased risk of death in patients with chronic Chagas disease. Methods: Repolarization heterogeneity was assessed using the V-index, a recently introduced metric founded on a biophysical model of the ECG. This metric provides an estimate of the ...
Juhasz L L University of Szeged, Department of Pharmacology and Pharmacotherapy, Szeged, - - 2014
The aim of the present study was to assess nitric oxide synthase (NOS) activity during a 25 min coronary artery occlusion and following preconditioning (PC) in anaesthetized dogs. In three groups of control dogs (n=9), the hearts were removed following a) euthanasia, b) 5 min and c) 25 min occlusion ...
Van Hout G P J GP University Medical Center Utrecht, Division Heart and Lungs, Experimental Cardiology, Utrecht, - - 2014
Successful translation of pre-clinical treatment strategies into clinical therapies depends on reproducible, conclusive models. To date, two distinctive procedures for the induction of myocardial ischemia-reperfusion to test novel therapies for myocardial infarction (MI) are commonly used. The first method applies coronary artery ligation via an open chest procedure, requiring invasive ...
De Boer M M Erasmus Medical Center, Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Rotterdam, - - 2014
The prevalence of heart failure is increasing due to improved survival of cardiovascular disease in an aging population. Interestingly, the normal aging heart already undergoes structural and functional alterations which are reminiscent to the changes observed in the failing heart. These alterations may increase the vulnerability of the aging heart ...
Shin D I DI Catholic University of Korea, Seoul, Korea, Republic - - 2014
Vasospastic angina (VA) has been reported to be more frequent in the East than in the West. However, in Korea, a grand scale analysis has not been done yet. We planned to set the multi-center registry for Korean VA. Total 11 centers of 9 universities participated in prospective, web-based VA-KOREA ...
Shalaeva E E Tashkent Medical Academy, Tashkent, - - 2014
Objective of the study was to assess viable myocardium in patients with left ventricular aneurysm, according to myocardial perfusion scintigraphy with Tc 99m - technetril. 64 patients aged from 45 to 65 years (mean age 52 ± 12,5), 61 males and 1 female were examined in the Republican Specialized Center ...
Tagieva N N Russian Cardiology Research and Production Complex, Acute cardiac care, Moscow, Russian - - 2014
Title: Vulnerable index (VI) detected by virtual histology intravascular ultrasound (VH-IVUS) in diseased coronary segments in patients with acute myocardial infarction and stable angina pectoris. The present study examined the relationship between the clinical presentation of coronary artery disease and the plaque characteristics of nonculprit segment assessed by virtual histology ...
Krestjyaninov Mv M Ulyanovsk Regional Hospital of War Veterans, Functional diagnostics, Ulyanovsk, Russian - - 2014
It's well known that left ventricle (LV) geometry type is strongly associated with stroke and myocardial infarction in hypertensive patients. The most negative prognosis have persons with concentric hypertrophy of LV and concentric remodelling of LV. Both cardiomyocytes and extracellular matrix are involved in left ventricle remodelling process and their ...
Pickard J M J JM Hatter Cardiovascular Institute, London, United - - 2014
Remote ischaemic conditioning (RIC) is a phenomenon of great potential clinical significance, being a non-invasive method to limit lethal reperfusion injury. Moreover, the identity of the putative cardioprotective factor, released from the remote organ, has been the subject of many recent studies. In this regard, cardioprotection via transfer of coronary ...
Kranjec Igor I Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, - - 2014
The purpose of this study was to assess the incidence, predictors, and presentation of target vessel failure (TVF) after primary stenting for ST-segment elevation myocardial infarction (MI) as opposed to elective stenting. A total of 8237 consecutive patients undergoing urgent or elective percutaneous coronary intervention (PCI) were enrolled in our ...
Lowenstein Jorge A JA Investigaciones Médicas, Buenos Aires, Argentina. Electronic address: - - 2014
Coronary flow velocity reserve (CFVR) increases the diagnostic sensitivity of stress echocardiography. The aim of this study was to evaluate the prognostic value of CFVR in patients without new wall motion abnormalities during pharmacologic stress echocardiography. The outcomes of 651 patients with normal wall motion response during stress echocardiography with ...
Yossof M M A MM Mansoura Specialized Medical Hospital (MSMH), Mansoura, - - 2014
Atherosclerosis is the leading cause ofIHD. Toll-like receptors (TLRs) have been identified as innate immune receptors, expressed in the cardiovascular system and may be a link between cardiovascular diseases and the activation of the immune system. To prove the association of TLRs2 with the risk of ischemic heart diseases. Patients ...
Khan A A Beaumont Hospital, Dublin, - - 2014
Fractional Flow Reserve (FFR) is a guide wire-based procedure that can accurately measure flow through a specific part of the coronary artery by placing a pressure guidewire across the lesion and pharmacologically induced hyperaemia.The aim of our study was to determine the long term clinical cardiovascular outcome, of patients who ...
Shah Jms J Om Diabetes Clinics and Research Centres, Thane West, - - 2014
PEP ( Presystolic period) and PWV(Pulse wave velocity ) measurements to assess and predict early cardiac (sub clinical) involvement in asymptomatic diabetic patients. 610 diabetic patients coming to Om Diabetes Centers without known heart history or complaints - subjected to routine investigations like Colin vascular profiler 1000( U S FDA ...
Qi Xiaolong X Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine, Shanghai, - - 2014
We aim to compare the midterm outcomes between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in diabetic patients who had multivessel coronary artery diseases (CAD). A comprehensive literature search was conducted to identify the related clinical studies with a follow-up for 1 year at least. The endpoints ...
Te Rijdt Wp W University Medical Center Groningen, Cardiology, Groningen, - - 2014
To examine the gross and microscopic pathological features of complete heart specimens from patients carrying the phospholamban (PLN) p.Arg14del mutation and to test our hypothesis that this mutation leads to aggregation and autophagy of mutant PLN protein in cardiomyocytes. Sixteen hearts were studied, acquired from 8 male and 8 female ...
Gacon J J E. Szczeklik Hospital, Department of Invasive Cardiology, Tarnow, - - 2014
Objective Circulating microRNAs (miRNAs) are recognized as useful cardiovascular biomarkers in acute coronary syndrome (ACS). Vessel occlusion is not always manifested with ST-elevation; no specific biomarkers have been identified to differentiate ACS with patent or occluded infarct-related coronary artery (IRA). Methods Forty-four consecutive patients (mean age 57.5±9.9 years) with uncomplicated ...
Skyschally A A University of Essen Medical School, Institute for Pathophysiology, Essen, - - 2014
Ischemic preconditioning (IPC), i.e. brief periods of ischemia/reperfusion (I/R) prior to prolonged ischemia, protects the myocardium from irreversible damage and reduces final infarct size. IPC is believed to act through reduction of reperfusion injury. We have now analyzed continuously recorded ECG-derived parameters, notably the time course of ST-segment deviation and ...
Casos K K University Hospital Vall d'Hebron, Department of Reparative Therapy of the Heart.Cardiac Surgery Department.Vall d'Hebron Research Inst, Barcelona, - - 2014
Ischemic heart disease is the major cause of death in developed countries and infarct size is the major determinant of prognosis. Ischemic postconditioning (IPostC), a sequence of short reperfusion-ischemia episodes after a prolonged ischemic period, has been proposed as a useful approach to reduce infarct size in all species, including ...
Krestjyaninov Mv M Ulyanovsk Regional Hospital of War Veterans, Functional diagnostics, Ulyanovsk, Russian - - 2014
Arrhythmias development determined by structural alterations of the heart, renin-angiotensin system activity and genetic factors. The purpose of our study was to evaluate angiotensin 2 receptor type 1 (AT2P1) gene polymorphism effect on development of arrhythmias in hypertensive patients. Were examined 125 patients with arterial hypertension (AH) 1-3 grade complicated ...
Oosterhoff P P Netherlands Heart Institute (ICIN), Utrecht, - - 2014
Pronounced beat-to-beat variability in cardiac repolarization duration (BVR) is associated with increased arrhythmic risk in patients, animal models and isolated cardiomyocytes. However, the mechanisms linking an enhanced BVR to arrhythmogenicity is unknown and may differ between single cells and the intact heart, since cellular coupling is known to attenuate repolarization ...
Kleinbongard P P University of Essen Medical School, Institute of Pathophysiology, Essen, - - 2014
In pigs, ivabradine reduced infarct size even when given only at reperfusion and in the absence of heart rate reduction (atrial pacing). The mechanism of such non-heart rate-related cardioprotection is unknown. Pentobarbital-anesthetized C57Bl/6J mice received ivabradine (1.7 mg/kg i.v. ± left atrial pacing) or placebo and were subjected to occlusion ...
Tribulova N N Slovak Academy of Sciences, Institute for Heart Research, Bratislava, Slovak - - 2014
Hypertension remains the most prevalent risk factor that increases propensity of the heart to the malignant arrhythmias due to myocardial remodeling. Data, including ours, suggest that hypertension is accompanied by melatonin and omega-3 FA deficiency but enhanced free radicals production. In turn, high BP was reduced in pts and/or animals ...
Sommer G G Graz University of Technology, Institute of Biomechanics, Graz, - - 2014
In the multidisciplinary field of heart research it is of utmost importance, for the description of phenomena like mechanoelectric feedback or heart wall thickening, to identify accurate myocardium material properties. Therefore this study aims to determine biaxial tensile and triaxial shear properties of the passive human ventricular myocardium. This novel ...
Gedik N N University Hospital of Essen (Ruhr), Institute of Pathophysiology, Essen, - - 2014
Remote ischemic preconditioning (RIPC) by repeated brief limb ischemia/reperfusion reduces myocardial injury in patients undergoing coronary artery bypass grafting (CABG). Activation of signal transducer and activator of transcription 5 (STAT5) in left ventricular (LV) myocardium at early reperfusion is associated with such protection. Autophagy, i.e., removal of dysfunctional cellular components ...
Postma S - - 2014
Pre-hospital infarct diagnosis gives the opportunity to start anti-platelet and anti-thrombotic agents before arrival at the PCI centre. However, more evidence is necessary to demonstrate whether high dose (HD) clopidogrel (600 mg) administered in the ambulance is associated with improved initial patency of the infarct related vessel (IRV) and/or clinical ...
Alameddine Abdallah K AK Division of Cardiac Surgery, Baystate Medical Center, Springfield, - - 2014
Red blood cell transfusion (Tx) induces a proinflammatory state. Inflammatory mediators are associated with an increased risk of postoperative atrial fibrillation (AF). Therefore, in this study we determined the association between AF and Tx after isolated coronary artery bypass graft surgery (CABG). Between January 2008 and December 2010, a total ...
Sandoval Yader Y Division of Cardiology, Department of Medicine, Hennepin County Medical Center, Minneapolis, - - 2014
To determine the ability of serial cardiac troponin (cTnI) changes (delta) to distinguish type 1 and type 2 myocardial infarction (MI) (excluding all ST-segment elevation MIs (STEMIs)) and describe the diagnostic accuracy and 180-day mortality in MI versus no-MI patients. Serial cTnIs were measured in 1112 consecutive patients without STEMI ...
Phomakay Venusa V Department of Pediatrics, Arkansas Children's Hospital, Little Rock, - - 2014
Williams syndrome (WS) is a congenital, multisystem developmental disorder affecting 1 in 8000 live births. Cardiovascular abnormalities are present in 80% of WS patients. The present study sought to characterize fully the electrocardiographic findings in WS and correlate findings with anatomic pathology. A retrospective review was performed of the electrocardiograms ...
Ismail Tevfik F TF Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK Imperial College London, London, - - 2014
Myocardial fibrosis identified by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) in patients with hypertrophic cardiomyopathy (HCM) is associated with adverse cardiovascular events, but its value as an independent risk factor for sudden cardiac death (SCD) is unknown. We investigated the role of LGE-CMR in the risk stratification of ...
Repossini Alberto A University of Brescia, Medical School, Brescia, Italy. Electronic address: - - 2014
Hybrid coronary revascularization, meaning, left mammary artery on left anterior descending artery combined with non-left anterior descending artery percutaneous coronary intervention stenting, is considered a viable alternative to conventional coronary artery bypass graft surgery or to multivessel percutaneous coronary intervention, to perform a functionally complete revascularization. One hundred consecutive patients ...
Morley-Smith Andrew C AC National Institute for Health Research Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, UK; National Heart and Lung Institute, Imperial College London, London, UK; Institute of Molecular and Translational Therapeutic Strategies, Integrated Research and Treatment Center Transplantation, Hannover Medical School, Hannover, - - 2014
There are few non-invasive techniques to predict and monitor patients' responses to left ventricular assist device (LVAD) therapy. MicroRNAs (miRs) are small non-coding RNAs with intricate roles in cardiovascular disease. They are stable in the circulation, readily quantified, and may be useful as new biomarkers. This study sought to identify ...
Iqbal M Bilal MB From the Royal Brompton and Harefield NHS Foundation Trust, Harefield Hospital, Middlesex, United Kingdom (M.B.I., A. Arujuna, C.I., M.D.); UCL Hospitals NHS Foundation Trust, Heart Hospital, London, United Kingdom (T.C., P. Meier); Kings College Hospital, King's College Hospital NHS Foundation Trust, London, United Kingdom (S.K., P. MacCarthy); Barts Health NHS Trust, The London Chest Hospital, London, United Kingdom (A. Archbold, C.K., A.M., D.B., K.R., A.W.); St. George's Healthcare NHS Foundation Trust, St. George's Hospital, London, United Kingdom (S.F., P.L.); Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom (I.S.M.); Royal Free London NHS Foundation Trust, London, United Kingdom (R.D.R.); BHF Centre of Excellence, Kings College London, St. Thomas' Hospital, London, United Kingdom (S.R.); and London Ambulance Service, London, United Kingdom - - 2014
Compared with transfemoral access, transradial access (TRA) for percutaneous coronary intervention is associated with reduced risk of bleeding and vascular complications. Studies suggest that TRA may reduce mortality in patients with ST-segment-elevation myocardial infarction. However, there are few data on the effect of TRA on mortality, specifically, in patients with ...
Dahlviken Rønnaug M RM Institute of Nursing, Bergen University College, Bergen, Norway; Department of Cardiology, Oslo University Hospital, Oslo, - - 2014
Takotsubo cardiomyopathy is a reversible condition mimicking acute myocardial infarction. The phenomenon is associated with emotional and physical stressful trigger events. Evidence-based patient counselling should be based on disease-specific knowledge of patient experiences. The aim of the study was to describe women's experiences of Takotsubo cardiomyopathy in a short-term perspective. ...
Han Xiao X Department of Geography, Tourism and Environment College of Shaanxi Normal University, Xi'an, 710119 Shaanxi, China. Electronic address: - - 2014
The aim of this paper is to analyze the geographical distribution of reference value of aging people's left ventricular end systolic diameter (LVDs), and to provide a scientific basis for clinical examination. The study is focus on the relationship between reference value of left ventricular end systolic diameter of aging ...
1 2 3 4 5 6 7 8 9 10 >