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Fan XiaoHan X State Key Laboratory of Cardiovascular Disease, Cardiac Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, - - 2014
To determine the incidence and predictors of sudden cardiac death (SCD) in the current era of revascularisation of myocardial infarction (MI) survivors with reduced LVEF. A prospective observational study was conducted in FuWai Hospital from 2004 to 2009. A total of 1018 consecutive patients who had an LVEF ≤35% and ...
Danzi Gian Battista GB Division of Cardiology, Ospedale "Santa - - 2014
Background:Permanent polymer coatings on drug-eluting stents (DES) surface have been identified as triggers of adverse events following percutaneous coronary intervention (PCI). However, efficacy and safety data for the Nobori biolimus-eluting stent (BES), a biodegradable polymer DES, are limited, so the aim of this study was to evaluate clinical outcomes associated ...
Kim Yong-Hyun YH Division of Cardiology, Department of Internal Medicine, Korea University Ansan - - 2014
Few studies have examined the variations in longitudinal/circumferential/radial strain (LS/CS/RS) and strain rate (LSr/CSr/RSr) in individual hearts when the left ventricular ejection fraction (LVEF) has changed. We hypothesized the relationships of strain/strain rate and LVEF are not linear, but vary with multiple inflection points (IPs) in individual hearts.Twenty-five patients with ...
Teh Andrew W AW Helmsley Electrophysiology Center, Mount Sinai School of Medicine, New York City, NY, USA; Monash University Eastern Health Cardiology Department, Victoria, Australia; Department of Cardiology, Austin Hospital, Victoria, - - 2014
Standard unipolar radiofrequency ablation (RFA) is typically successful in eliminating premature ventricular contractions (PVCs) originating from the ventricular outflow tract region. In a minority of cases, this approach may be ineffective. We report four cases where bipolar RFA was attempted after failed unipolar RFA. From a total of 73 consecutive ...
Wang Ying Y Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, 1#Yixueyuan Road, Chongqing 400016, - - 2014
Adiponectin is an adipose-secreting protein that shows atheroprotective property and has inverse relation with coronary artery disease (CAD). High-molecular weight (HMW) adiponectin is reported as the active form of adiponectin. In the present study, we aimed to investigate the association between total adiponectin, HMW adiponectin, HMW-total adiponectin ratio and the ...
Birkemeyer Ralf - - 2014
It is uncertain whether gender differences in outcome after primary percutaneous coronary intervention (PCI) are only attributable to different baseline characteristics or additional factors. Databases of two German myocardial infarction network registries were combined with a total of 1104 consecutive patients admitted with acute ST-elevation myocardial infarction (STEMI) and treated ...
Richmond Tyler T From the *Central Baptist Heart and Vascular Institute, Lexington, KY; †Division of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, IL; and ‡Department of Emergency Medicine, Rush University Medical Center, Chicago, - - 2014
There has been considerable emphasis on the care of patients with ST-elevation myocardial infarction (STEMI) with the wide implementation of protocols to quickly identify and triage them from the emergency department (ED) to a cardiac catheterization laboratory for percutaneous coronary intervention. However, a small but important number of patients with ...
Zhang Yaojun Y Thoraxcenter, Erasmus Medical Center, Rotterdam, 3015CE, The - - 2014
Drug eluting stents (DESs) made with biodegradable polymer have been developed in an attempt to improve clinical outcomes. However, the impact of biodegradable polymers on clinical events and stent thrombosis (ST) remains controversial. We searched Medline, the Cochrane Library and other internet sources, without language or date restrictions for articles ...
Ağaç Mustafa Tarık MT Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey. - - 2014
Objectives: The major determinant of final infarct size for a given coronary occlusion is the size of the myocardial area-at-risk. We propose herein a new index 'Relative Importance Index (RII)' to predict area-at-risk in patients with anterior myocardial infarction (MI). The aim of the study was to assess the predictive ...
Chen Kang K Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Outpatient Department, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, - - 2014
Objective: We are aimed to investigate whether right ventricular mid-septal pacing (RVMSP) is superior to conventional right ventricular apical pacing (RVAP) in improving clinical functional capacity and left ventricular ejection fraction (LVEF) for patients with high-degree atrio-ventricular block and moderately depressed left ventricle (LV) function. Methods: Ninety-two patients with high-degree ...
Mohite Prashant N PN Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, Harefield Hospital, Hill End Road, Harefield, Middlesex, London, UB9 6JH, UK, - - 2014
Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support. The aim of this study was to evaluate factors influencing survival during short-term ventricular assist support in PCCS. In total, 154 CentriMag(®) (Thoratec; CA, USA) devices were implanted for cardiogenic shock between 2004 ...
Phan Thanh T The James Cook University - - 2014
The response to cardiac resynchronisation therapy (CRT) can be heterogeneous. Most studies aim to improve patient selection in order to achieve better outcomes.However, the adjustment of device timing intervals in conjunction with optimisation of medical therapy may maximise the effectiveness of CRT. This approach provides a new paradigm in the ...
Levelt Eylem E OCand DPAG, University of Oxfor Technical - - 2014
Large, population based studies have shown that diabetes mellitus (DM) of long durationis associated with increased incidence of heart failure, independent of underlying hypertension and coronary artery disease. Cardiovascular magnetic resonance imaging (CMR) and magnetic resonance spectroscopy (MRS) provide comprehensive, non-invasive, multiparametric measures of the functional, structural and metabolic status ...
Ferreira Vanessa V University of - - 2014
Up to 10% of patients presenting with chest pain and elevated troponin levels demonstrate non-obstructive coronary arteries on angiography, posing a clinical challenge in diagnosis, prognosis and management. The final diagnosis has important implications for the patient, including prescription for treatment and fitness for permissible activities, occupation and medical insurance. ...
Malhotra Aneil A St. George's University of - - 2014
Hypertrophic cardiomyopathy (HCM) is the commonest cause of SCD in young athletes. The differentiation between physiological left ventricular hypertrophy (LVH) and morphologically mild hypertrophic cardiomyopathy (HCM) is crucial and an erroneous diagnosis has potentially serious consequences. Day to day clinical practice most commonly utilises transthoracic echocardiography (ECHO) for this purpose. ...
Wilson William W Royal Infirmary of - - 2014
Historical data suggest that patients with multi-vessel coronary disease involving the left main stem or proximal left anterior descending artery may gain prognostic benefit from coronary artery bypass grafting (CABG). Whether percutaneous coronary intervention (PCI) achieves similar outcomes remains unclear. We performed a retrospective linkage study to determine outcomes in ...
Chowdhury Anika A Ninewells Hospital and Medical - - 2014
Heart failure is a very common condition in the UK with a significant proportion of newly diagnosed patients dying within a year. The prognostic implications of surface electrocardiogram (ECG) markers in chronic heart failure (CHF) patients are not well characterised. This study aims to determine whether the presence of surface ...
Rauhalammi Samuli S BHF Glasgow Cardiovascular Research - - 2014
T1 and T2 cardiac magnetic resonance (CMR) mapping methods have shown promise for infarct characterisation in patients with acute ST-elevation myocardial infarction (STEMI). Non-ST elevation MI is typically a sub-acute problem with infarct characteristics that are less readily defined. We prospectively studied the diagnostic accuracy of two novel (T1, T2 ...
Ghattas Angie A University of Birmingham Centre for Cardiovascular - - 2014
Monocytes, with 3 different subsets, are implicated in the initiation and progression of the atherosclerotic plaque contributing to plaque instability and rupture. Mon1 are the "classical" monocytes with inflammatory action, whilst Mon3 are considered reparative with fibroblast deposition ability. The function of the newly described Mon2 subset is yet to ...
Spyridopoulos Ioakim I Newcastle University and Freeman - - 2014
: Early identification of higher risk patients presenting with ST-elevation myocardial infarction (STEMI) and undergoing primary percutaneous coronary intervention (PPCI) will allow a more aggressive strategy and approach. The aim of this study was to evaluate the shock index (ratio of heart rate/systolic blood pressure on admission) as a predictor ...
McGregor Kieran K BHF Centre for Cardiovascular Science, University of - - 2014
: Mice lacking the glucocorticoid regenerating enzyme 11β hydroxysteroid dehydrogenase type 1 (11βHSD1), responsible for local regeneration of corticosterone, have increased peri-infarct angiogenesis (Small et al ., 2005) and improved cardiac function (McSweeney et al ., 2010) following myocardial infarction (MI). The aim of the present study was to investigate ...
Castellan Raphael R University of - - 2014
: The neonatal murine heart has been shown to retain a capacity for regeneration following injury until 7 days after birth, after which injury is followed by scar formation (Porello et al ., 2011). However normal physiology and growth characteristics of the heart are poorly defined during this neonatal period. ...
Zhao Wei W Department of Cardiology, Peking University Third Hospital; Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, - - 2014
Recently, studies have disclosed soluble CD40 ligand (sCD40L) during atherosclerosis development and plaque destabilization. The objective of the present study was to test the hypothesis that sCD40L levels are higher in acute coronary syndrome (ACS) patients with a greater extent of angiographic coronary involvement. This cross-sectional study examined ACS patients ...
Neragi-Miandoab Siyamek S Department of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Albert-Einstein College of Medicine, Bronx, NY, - - 2014
Background: The TandemHeart device (THD) is a pump system that can be deployed percutaneously (PC) or via conventional surgical (CS) cannulation; it is capable of supporting one or both ventricles. It is a versatile system designed for use as a rescue device in acute heart failure and as a bridge ...
Navaravong Leenhapong L Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, - - 2014
Contrast-enhanced computed tomography angiography (CTA) of the coronaries allows identification of plaques. Limited data exists on the relationship between C-reactive protein (CRP) and the plaque type or plaque burden detected by CTA. We studied relationship between CRP and coronary atherosclerosis. 92 patients without history of coronary disease underwent coronary CTA ...
Akyildiz Zehra Ilke - - 2014
Cardiologists' approach to angina in outpatients with stable coronary artery disease (CAD) is unclear. Therefore, we analysed data from the national multicentre, observational PULSE study to evaluate the frequency of angina, clinical variables affecting angina frequency and the impact of frequent angina on quality of life (QoL) in outpatients with ...
Shmuely Haim - - 2014
The relationship between Helicobacter pylori infection and coronary artery disease (CAD) has as yet not been fully examined. The myocardial perfusion imaging (MPI) stress test has proven its efficacy as an integral part of diagnosing CAD. To investigate the association between CAD and H. pylori infection using MPI. This prospective ...
Khurshid Shaan S Cardiovascular Division, Electrophysiology and Heart Failure Sections, Hospital of the University of Pennsylvania, Philadelphia, - - 2014
Frequent right ventricular (RV) pacing can lead to a decline in LVEF. To identify incidence and predictors of RV pacing-induced cardiomyopathy (PICM). We retrospectively studied 1,750 consecutive patients undergoing pacemaker implantation between 2003 and 2012. Patients were included if baseline LVEF was normal, single chamber ventricular or dual chamber pacemaker ...
Dwyer Nathan B NB Department of Cardiac Sciences and Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada - - 2014
The purpose of this study was to determine whether ischemic postconditioning (IPC) could improve peripheral endothelial function in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Of 102 patients randomly assigned to an IPC or standard protocol to study infarct size utilizing cardiovascular magnetic ...
Ielasi Alfonso A Department of Cardiology, Azienda Ospedaliera 'Bolognini', Seriate (BG), Italy *Drs Ielasi and Silvestro contributed equally to the manuscript and are joint first - - 2014
Unprotected left main (ULM) related ST-segment elevation myocardial infarction (STEMI) is a severe event, often leading to circulatory failure and/or sudden cardiac death. Although high-risk ULM thrombosis populations treated by primary percutaneous coronary intervention (PPCI) have been previously described, very little is known regarding the outcomes following PPCI for ULM-related ...
Chen Jun J Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, 300, Guangzhou Road, Nanjing, 210029, - - 2014
The aim of this study was to obtain best estimates of the efficacy and safety of cilostazol-based triple antiplatelet therapy (TAPT: aspirin, clopidogrel and cilostazol) compared with dual antiplatelet therapy (DAPT: aspirin and clopidogrel) in patients undergoing coronary stent implantation. We searched the literature to identify all randomized clinical trials ...
Gau Sören S From the Department of Cardiology, University of Erlangen, Erlangen, - - 2014
Recent studies have shown a significant correlation between increased epicardial fat volume (EFV) and mortality, coronary artery disease events, and measures of coronary atherosclerotic burden, for example, coronary calcium. Patients with chronic kidney disease on hemodialysis have an increased prevalence of coronary atherosclerosis and coronary calcium. The mechanisms underlying both ...
Fontenla Adolfo A Unidad de Arritmias, Servicio de Cardiología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address: - - 2014
Implantable cardioverter-defibrillators reduce mortality in some patients with heart disease. Battery replacement is a frequent occurrence in clinical practice and is required in up to 30% of implants. The benefit/risk ratio of defibrillators varies over time and should be reevaluated at the time of replacement. The aim of this study ...
Nørgaard Kirsten Schou - - 2014
Abstract Objectives. We investigated whether any change in the use of invasive coronary angiography and coronary revascularisation after CT coronary angiography in patients with a low to intermediate pre-test probability of coronary artery disease could be explained from alterations in patient characteristics. Design. A cohort study based on data samples ...
Yang Linfeng L Department of Medical Imaging, Jinan Military General Hospital, No, 25, Shifan Road, Jinan, Shandong Province, China, 250031, - - 2014
To investigate the diagnostic performance of coronary computed tomographic angiography (CCTA) with prospective electrocardiograph (ECG) gating based on step-and-shoot (SAS), Flash and volume imaging modes. We searched the electronic databases PubMed for all published studies regarding CCTA. We used an exact binomial rendition of the bivariate mixed-effects regression model developed ...
Zahid Wasim W Department of Cardiology and Center for Cardiological Innovation, Oslo University Hospital, Rikshospitalet, N-0027 Oslo, Norway The Intervention Center, Oslo University Hospital, Oslo, Norway University of Oslo, Oslo, - - 2014
Ischaemic myocardial segments tend to stretch as the intraventricular pressure rises steeply during the isovolemic contraction phase, before they contract during ejection. We hypothesized that the time they remain stretched, called duration of early systolic lengthening (DESL), correlates with final infarct size as defined by contrast enhanced magnetic resonance imaging ...
Wildgruber Moritz M From the *Institut für Diagnostische und Interventionelle Radiologie; †Klinik und Poliklinik für Vaskuläre und Endovaskuläre Chirurgie, ‡Institut für Medizinische Statistik und Epidemiologie, and §Zentrum für Prävention und Sportmedizin, Klinikum Rechts der Isar, Technische Universität München, Munich, - - 2014
The aim of this study was to compare the contrast-to-noise ratio (CNR) values of infarct and remote myocardium as well as infarct and blood after application of 0.1 mmol/kg gadobutrol and 0.1 mmol/kg gadobenate dimeglumine on late gadolinium enhancement magnetic resonance (MR) images. The study was a prospective randomized controlled ...
Khan Jamal N - - 2014
Microvascular obstruction (MVO) describes suboptimal tissue perfusion despite restoration of infarct-related artery flow. There are scarce data on Infarct Size (IS) and MVO in relation to the mode and timing of reperfusion. We sought to characterise the prevalence and extent of microvascular injury and IS using Cardiovascular magnetic resonance (CMR), ...
Andrade Pedro Beraldo de PB Santa Casa de Misericórdia de Marília, São Paulo, SP, - - 2014
Background: The radial access provides a lower risk of bleeding and vascular complications related to the puncture site in comparison to the femoral access. Recent studies have suggested a reduction in mortality associated with the radial access in patients with acute myocardial infarction undergoing percutaneous coronary intervention. Objective: To compare ...
Niccoli Giampaolo G Institute of Cardiology, Catholic University of the Sacred - - 2014
Background:Pre-infarction angina (PIA) has been shown to reduce the microvascular obstruction (MVO) rate in patients with ST-segment elevation myocardial infarction (STEMI). We sought to evaluate the potential modulator role of cardiovascular risk factors (CRFs) on this protective effect.Methods and Results:Two hundred patients with STEMI were enrolled. PIA was defined as typical chest ...
Di Bari Mauro M Department of Experimental and Clinical Medicine, Research Unit of Medicine of Aging, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, - - 2014
Application of percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS) is suboptimal in older frail individuals. This study was conducted to verify if background risk is a risk factor for underuse and diminished effectiveness of PCI in older patients. An observational cohort study was conducted using data ...
Xu Qiu-Qin QQ Department of Pediatric Cardiology, Children's Hospital Affiliated of Soochow University, 303 Jingde Road, Suzhou, 215003, Jiangsu, - - 2014
The current study aimed to assess left ventricular (LV) longitudinal systolic strains in children with KD using two-dimensional speckle-tracking imaging and to analyze the relationship of LV myocardial deformation to coronary lesions and laboratory markers. The study enrolled 101 children with acute KD. An additional 50 age- and gender-matched normal ...
Jinatongthai Peerawat P Pharmacy Practice Division, Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, - - 2014
CRUSADE risk score stands out as a simple-to-use bleeding risk model. However, its use is still doubtful for Thai population. The aim of this study was to assess the prognostic value of CRUSADE in predicting risk of major bleeding among Thai patients with acute coronary syndrome (ACS) receiving enoxaparin. A ...
Gibson Michael C MC Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address: - - 2014
Significant improvements in door-to-balloon times have led to a reduction in mortality in ST-segment elevation myocardial infarction; however, mean symptom-to-door times remain at 2 to 3 hours. An intracardiac electrogram monitoring device may be beneficial in high-risk patients by alerting them to rapidly progressive ST-segment changes indicative of acute coronary ...
Martin Anne-Céline AC Cardiology Department, Military Hospital Val de Grâce, Paris, - - 2014
Cardiovascular diseases remain the most common cause of death in older adults. Guidelines state that advanced age alone should not limit the use of invasive therapy. However, coronary angiograms and subsequent revascularization are often not carried out in octogenarians. The benefit/risk balance of an invasive strategy and the decision-making process ...
Yamaki Takayoshi T Departments of Cardiology and Hematology,Fukushima Medical - - 2014
The incidence of cardiovascular disease (CVD) reportedly increases following a huge disaster. On March 11, 2011, the Great East Japan Earthquake hit a large area of eastern Japan. In Fukushima prefecture, many people suffered from the consequences of the earthquake, the subsequent tsunami, and especially the Fukushima Daiichi Nuclear Power ...
Kaneko Kazuyoshi K Department of Cardiology, Kitamurayama Municipal Hospital, 2-15-1 Onsen-machi, Higashine, Yamagata, 999-3792, Japan, - - 2014
To evaluate left atrial appendage (LAA) dysfunction using left atrial pulse-wave tissue Doppler imaging (PW-TDI) in acute cerebral embolism (ACE) patients with sinus rhythm (SR), transthoracic (TTE) and transesophageal echocardiograhy (TEE) were performed in 60 consecutive patients with SR without obvious left ventricular dysfunction within 2 weeks after ACE. Two groups ...
Nagayoshi Yasuhiro Y National Health Insurance Aso Central Hospital, Aso City, Japan; Department of Cerebrovascular and Acute Coronary Syndrome, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan. Electronic address: - - 2014
On July 12, 2012, heavy rains struck southwest Japan, particularly in the Mount Aso area. Huge mud slides in the mountains destroyed houses, and heavy rains caused severe flooding in the inhabited areas. We investigated the incidence of cardiovascular events after the disaster. We investigated patients who were admitted to ...
Hashimoto Ikuo I Department of Pediatrics, Toyama City - - 2014
Background:Many studies have investigated tricuspid annular plane systolic excursion (TAPSE) as a longitudinal right ventricular (RV) contraction. The aim of this study was to clarify the mechanism of RV systolic function compared with longitudinal and radial RV contractions in healthy children.Methods and Results:A total of 815 consecutive healthy children and adolescents were ...
Nakashima Hiroshi H Department of Cardiology, Nagasaki Citizens Hospital, Japan - - 2014
It is unclear whether obstructive sleep apnea (OSA) increases the recurrence of acute coronary syndrome (ACS) in patients with acute myocardial infarction (MI). We hypothesized that moderate-to-severe OSA increased the number of adverse cardiovascular events in patients who underwent primary percutaneous coronary intervention (PCI). This study included 272 patients with ...
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