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Narula Amar A NYU Langone Medical Center, New York, NY, - - 2014
We sought to examine the short- and long-term outcomes of patients who developed contrast-induced acute kidney injury (CI-AKI; defined as an increase in serum creatinine of ≥0.5 mg/dL or a 25% relative rise within 48 h after contrast exposure) from the large-scale HORIZONS-AMI trial. Multivariable analyses were used to identify ...
Chrispin Jonathan J Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: - - 2014
To examine the association between LVH, defined by cardiovascular magnetic resonance (CMR) and electrocardiography (ECG), with incident AF. Previous studies of the association between atrial fibrillation (AF) and left ventricular hypertrophy (LVH) were based primarily on echocardiographic measures of LVH. The Multi-Ethnic Study of Atherosclerosis (MESA) study enrolled 4942 participants ...
Barta Kitti K Division of Nephrology, Department of Medicine, Medical and Health Science Centre, University of Debrecen, Pf. 19. Nagyerdei Krt. 98, Debrecen, 4012, - - 2014
The prolongation of the QT interval and dispersion could predict ventricular arrhythmias. It is not yet established whether there is a difference between the effects of hemodialysis and hemodiafiltration on QT interval duration and dispersion. Data of thirty patients was investigated while they were receiving hemodiafiltration over a period of ...
Ozcan Fırat F Cardiology Clinic, Türkiye Yüksek Ihtisas Training and Research Hospital, Ankara, - - 2014
Fragmented QRS complex (fQRS) is associated with worse outcomes in several cardiovascular conditions. However, alterations in fQRS in patients with ST elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI) and association of fQRS with myocardial blush grade (MBG) has not been investigated until now. In this study, ...
Filippatos Gerasimos G Department of Cardiology, Attikon University Hospital, University of Athens Medical School, - - 2014
Temporal trends of epidemiological data on acute heart failure (AHF) are limited. We sought to assess changes in epidemiology, clinical presentation and management of AHF in Greece using data from two international registries conducted three years apart. The Acute Heart Failure Global Registry of Standard Treatment (ALARM-HF) and the European ...
Rodriguez-Pascual Carlos C Departments of Geriatric - - 2014
Background-In older adults hospitalized for heart failure, a poor score on a comprehensive geriatric assessment (CGA) is associated with worse prognosis during hospitalization and at 1 month after discharge. However, the association between the CGA score and long-term mortality is uncertain.Methods and Results-This is a prospective study of 487 patients ...
Karimi Mohammad Taghi MT Rehabilitation Faculty, Isfahan University of Medical sciences, Isfahan, Iran. Tel.: +98 3117922021; Fax: +98 3116687270; E-mail: - - 2014
Heart rate is an accurate and easy to use method to represent the energy expenditure during walking, based on physiological cost index (PCI). However, in some conditions the heart rate during walking does not reach to a steady state. Therefore, it is not possible to determine the energy expenditure by ...
Zhou Tao T Department of Medical Imaging, Jinan Military General Hospital, No, 25, Shifan Road, Jinan, Shandong Province, China. - - 2014
The present meta-analysis illustrates the accuracy of myocardial perfusion SPECT (MPS) to diagnose functional stenotic coronary artery disease (CAD) with fractional flow reserve (FFR) as standard reference. All investigators screened and selected studies that compared MPS with FFR in symptomatic patients with suspected CAD. Patients and study characteristics were independently ...
Verdoia Monica M aDivision of Cardiology, Azienda Ospedaliera-Universitaria 'Maggiore della Carità', Eastern Piedmont University, Novara, Italy bDivision of Cardiology 'Azienda Ospedaliera Marche Nord', Pesaro, Italy cDepartment of Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy dDepartment of Cardiology, UMC St Radboud, Nijmegen, The Netherlands eBiochemistry, Department of Translational Medicine, Eastern Piedmont University, Novara, - - 2014
Acute coronary syndromes (ACSs) represent a high-risk condition, as enhanced platelet reactivity importantly influences myocardial perfusion and procedural results after percutaneous coronary intervention (PCI). In fact, higher rate of periprocedural myocardial infarction (PMI) and reduced event-free survival have been reported in these patients. The single nucleotide polymorphism Leu33Pro of platelet ...
Mumma Bryn E BE From the *Department of Emergency Medicine, University of California Davis, Sacramento, CA; †University of California Davis School of Medicine, Sacramento, CA; ‡Department of Emergency Medicine, Northwestern University, Chicago, IL; and §Department of Emergency Medicine, Kaiser Permanente South Sacramento, Sacramento, - - 2014
Of patients with ST segment elevation myocardial infarction (STEMI), approximately two thirds present to a hospital not capable of percutaneous coronary intervention. Transfer to a STEMI-receiving center delays time to reperfusion in patients with STEMI, but factors that affect this delay have not been well studied. We performed a 3-round ...
Botto Fernando F From the Hamilton General Hospital, David Braley Cardiac, Vascular, and Stroke Research Institute, Population Health Research Institute, Hamilton, Ontario, Canada (P.J.D.); and Members of The VISION Writing Group and VISION Investigators, who are listed in appendix 1 and appendix 2, respectively. Population Health Research Institute, Hamilton, Ontario, Canada; Department of Clinical Research, Estudios Clinicos Latino America (ECLA), Rosario, Argentina Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil, Colombia St. John's Medical College and Research Institute, Bangalore, India Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hospital General Universitario Gregorio Maranon, Madrid, Spain University of Alberta, Edmonton, Alberta, Canada University of Malaya, Kuala Lampur, Malaysia Research Institute Hcor (Hospital do Coracao), Sao Paulo, Brazil Barts & The London School of Medicine and Dentistry, London, United Kingdom University of Kwazulu-Natal, Durban, South Africa Christian Medical College, Ludhiana, India Universidad PeruanaCayetano Heredia, Lima, Peru The George Institute for Global Health, University of Sydney, Sydney, Australia Population Health Research Institute, Hamilton, Ontario, Canada; University of Kwazulu-Natal, Durban, South Africa Department of Clinical Epidemiology and Biostatistics, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hospital de Clinicas de Porto Alegre, Universidade Federal de Rio Grande do Sul, Brazil Jagiellonian University Medical College, Krakow, Poland The Cleveland Clinic, Cleveland, Ohio Population Health Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, - - 2014
Myocardial injury after noncardiac surgery (MINS) was defined as prognostically relevant myocardial injury due to ischemia that occurs during or within 30 days after noncardiac surgery. The study's four objectives were to determine the diagnostic criteria, characteristics, predictors, and 30-day outcomes of MINS. In this international, prospective cohort study of ...
Gómez-Talavera Sandra S Cardiovascular Institute, San Carlos University Hospital, Cardiology , Madrid , - - 2014
Abstract Introduction: Conduction disorders in patients with ST-segment elevation myocardial infarction (STEMI) are associated with high mortality. Previous studies have analyzed the implications of AVB in acute coronary syndrome treated with fibrinolysis. However, the implications of AVB in patients with STEMI treated with primary angioplasty have not been sufficiently studied. ...
Shang Qing Q From the Division of Cardiology, and the Division of Rheumatology, Department of Medicine and Therapeutics, Prince of Wales Hospital and Institute of Vascular Medicine, The Chinese University of Hong Kong, Hong Kong, - - 2014
Although early cardiovascular (CV) involvement has been found in patients with psoriatic arthritis (PsA), few studies have related this to PsA disease activity. The aim of our study was to evaluate left ventricular (LV) mechanics using novel, more sensitive techniques based on assessment of LV rotation for the detection of ...
Berezin Alexander E AE State Medical University, Internal Medicine Department, Zaporozhye, Ukraine. Electronic address: - - 2014
Despite a high potential of endothelial progenitor cells (EPC) for diagnostic purposes, the EPC role in developing ischemic chronic heart failure (CHF) has not been determined obviously. The objective of the study is to assess the counts of CD45(+)CD34(+), CD45(-)CD34(+), CD14(+)CD309(+), and CD14(+)CD309(+)Tie2(+) phenotyped circulating EPC of various subpopulations in ...
Yan Xinhua X CardioVascular Research Center, GeneSys Research Institute, Boston, MA, - - 2014
Background: During the future Moon and Mars missions, astronauts will be exposed to space radiation (IR) for extended time. The majority of space flight-associated risks identified for the cardiovascular (CV) system to date were determined shortly after low Earth orbit (LEO) short- and long-duration space flights that include: serious cardiac ...
Liu Yangchun Y Department of Cardiology, First Affiliated Hospital of Guangxi Medical University, Guangxi Cardiovascular Institute, Nanning, Guangxi 530021, - - 2014
Tirofiban has been widely used as an adjunctive pharmacologic agent for revascularization in patients undergoing percutaneous coronary intervention, and the outcomes appear attractive. However, the potential benefits from early administration of tirofiban in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) remain unclear. We ...
Hayrapetyan Hamlet Grigori HG Department of Urgent Cardiology, Erebouni Medical Centre, Yerevan, Armenia. - - 2014
Objectives: We aimed to assess the combined estimator of left ventricular (LV) myocardial performance index (MPI) and tricuspid annular plane systolic excursion (TAPSE) as a pooled independent predictive factor for hospital mortality and one-year mortality and re-hospitalization in patients with primary LV inferior ST segment elevation myocardial infarction (STEMI). Study ...
Tisminetzky Mayra M Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, - - 2014
Although acute myocardial infarction (AMI) occurs primarily in the elderly, this disease also affects young adults. Few studies have, however, presented data on relatively young patients hospitalized with AMI. The objectives of this population-based study were to examine recent trends in the magnitude, clinical characteristics, management, and in-hospital and long-term ...
Lam Ming Kai MK Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The - - 2014
Aims: To investigate the prognostic value of coronary dominance for various adverse clinical events following the implantation of drug-eluting stents. Methods and results: We assessed two-year follow-up data of 1,387 patients from the randomised TWENTE trial. Based on the origin of the posterior descending coronary artery, coronary circulation was categorised ...
Räber Lorenz L Department of Cardiology, Bern University Hospital, Bern, - - 2014
Pathology studies have shown delayed arterial healing in culprit lesions of patients with acute coronary syndrome (ACS) compared with stable coronary artery disease (CAD) after placement of drug-eluting stents (DES). It is unknown whether similar differences exist in-vivo during long-term follow-up. Using optical coherence tomography (OCT), we assessed differences in ...
Auger Dominique D Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands; Department of Cardiology, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, - - 2014
Right ventricular apical (RVA) pacing may induce left ventricular (LV) dyssynchrony. The long-term prognostic implications of induction of LV dyssynchrony were retrospectively evaluated in a cohort of patients who underwent RVA pacing. A total of 169 patients (62±13 years, 69% male) with high RVA pacing burden were included. Echocardiographic evaluation ...
Wang Tom Kai Ming TK Green Lane Cardiovascular Service, Auckland City Hospital, New - - 2014
Cardiac troponins are the preferred biomarkers for diagnosing myocardial infarction (MI). High-sensitivity troponin T (hs-TnT) assays have increased sensitivity and enable more rapid diagnosis of infarction. We assessed the prognostic utility of admission hs-TnT to detect outcomes after primary angioplasty for ST-elevation/new left bundle branch block myocardial infarction (STEMI). Patients ...
Goo Ja-Jun JJ Department of Internal Medicine, Maryknoll Medical Center, Busan, - - 2014
With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-system (RAS) blockers, which are also used in a variety of cardiovascular disorders. This study evaluated the ...
Sherwood Matthew W MW Duke Clinical Research Institute, Durham, North - - 2014
Studies have shown variation in the use of red blood cell transfusion among patients with acute coronary syndromes. There are no definitive data for the efficacy of transfusion in improving outcomes, and concerning data exist about possible association with harm. Current transfusion practices in patients undergoing percutaneous coronary intervention (PCI) ...
Bamberg Fabian F Department of Clinical Radiology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 15, 81377, Munich, Germany, - - 2014
The purpose of the study is feasibility of dynamic CT perfusion imaging to detect and differentiate ischemic and infarcted myocardium in a large porcine model. 12 Country pigs completed either implantation of a 75 % luminal coronary stenosis in the left anterior descending coronary artery simulating ischemia or balloon-occlusion inducing infarction. ...
Tanındı Aslı - - 2014
Abstract Objectives: We investigate the association between non-invasively determined central pulse waveform characteristics and the extent and severity of coronary artery disease (CAD) in patients undergoing coronary angiography with the clinical diagnosis of CAD. Design: We included 145 consecutive patients with stable angina pectoris (SAP), unstable angina pectoris (USAP) or ...
Modolo Rodrigo R Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas , Campinas, SP , - - 2014
White-coat hypertension (WCH), commonly found in pseudoresistant hypertension, does not pose higher cardiovascular risk than hypertensive status. However, when the decrease of the out-of-office blood pressure does not reach normal levels - the white-coat effect (WCE) - the repercussions are still obscure. We investigated the repercussions of the WCE in ...
Tilz Roland Richard RR Department of Cardiology, Asklepios Klinik St Georg, Lohmuehlenstr 5, 20099 Hamburg, - - 2014
Catheter ablation can abolish clinical ventricular tachycardia (VT) in patients after myocardial infarction (MI). However, VT frequently recurs after ablation. The best ablation strategy is still unknown, particularly in patients with unmappable VTs. We hypothesized that isolation of the arrhythmogenic substrate would be a feasible and effective ablation strategy for ...
Ong Peter P Robert-Bosch-Krankenhaus, Stuttgart, - - 2014
Coronary spasm can cause myocardial ischemia and angina in patients with and those without obstructive coronary artery disease. However, provocation tests using intracoronary acetylcholine administration (ACH-test) are rarely performed in clinical routine in the US and Europe. Thus, we assessed the clinical usefulness, angiographic characteristics and safety of the ACH-test ...
Adlbrecht Christopher C Medical University of Vienna, Department of Internal Medicine II, Division of - - 2014
Ventricular arrhythmias are common after acute myocardial infarction (AMI). Endothelin (ET) is a mediator of microvascular dysfunction and cardiac remodeling with arrhythmogenic potential. The aim of this study was to assess safety and feasibility of selective ET-A receptor blockade in ST-elevation acute coronary syndrome (STE-ACS) within a larger randomized trial. ...
Kosiuk Jedrzej J Department of Electrophysiology, Heart Center, Leipzig, Strümpellstr. 39, 04289 Leipzig, - - 2014
Recurrence of atrial fibrillation (AF) is frequently observed after AF catheter ablation. However, the predictive value of echocardiographic parameters associated with left ventricular diastolic dysfunction (LVDD) has not been well studied.METHODS AND RESULTS: In 124 consecutive patients (mean age 61 ± 10 years, 60% male) with paroxysmal (n = 70) ...
Bilchick Kenneth C KC Department of Medicine, Cardiovascular Division, University of Virginia Health System, Charlottesville, VA. Electronic address: - - 2014
Using cardiac magnetic resonance (CMR), we sought to evaluate the relative influences of mechanical, electrical, and scar properties at the left ventricular (LV) lead position (LVLP) on CRT response and clinical events. CMR cine displacement encoding with stimulated echoes (DENSE) provides high quality strain for overall dyssynchrony (circumferential uniformity ratio ...
Kraaier Karin K Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER, Enschede, The Netherlands, - - 2014
Microvolt T-wave alternans (MTWA) is an electrocardiographic marker for predicting sudden cardiac death. In this study, we aimed to study the relation between MTWA and scar assessed with cardiac magnetic resonance imaging (CMR) in patients with ischemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM). Sixty-eight patients with positive or negative MTWA ...
Brener Sorin J SJ New York Methodist Hospital, Brooklyn, NY, - - 2014
Aims: To determine the relation between thrombus aspiration (TA) and/or intra-lesion (IL) abciximab with pre-stent Thrombolysis In Myocardial Infarction (TIMI) flow grade and infarct size (IS) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Methods and results: The INFUSE-AMI trial randomised 452 patients with anterior ...
Tousek Petr P Cardiocenter, Charles University Prague, Third Faculty of Medicine, Prague, Czech - - 2014
The incidence and treatment strategies of acute coronary syndrome (ACS) vary by region. Additionally, the clinical spectrum of ACS is changing and outcomes are improving. We assessed the incidence, treatment strategies, and outcomes of ACS for a well-defined population within a well-established network of percutaneous coronary intervention (PCI) centers and ...
de Groote Pascal P 1Service de Cardiologie, Pôle Cardio-Vasculaire et Pulmonaire, Centre Hospitalier Régional et Universitaire de Lille, Lille, France; Inserm U744, Institut Pasteur de Lille, Université de Lille 2, Lille, - - 2014
-Some patients with left ventricular systolic dysfunction (LVSD) have a dramatic improvement in left ventricular ejection fraction (LVEF) after beta-blockade. No study has analyzed the long term echocardiographic and clinical follow-up of this subgroup of patients. -We included in this analysis 174 consecutive patients with LVSD who had a LVEF ...
Carrick David D BHF Glasgow Cardiovascular Research Center, Institute of Cardiovascular and Medical Sciences, University of Glasgow, New York City; West of Scotland Heart and Lung Center, Golden Jubilee National Hospital, New York - - 2014
To assess whether deferred stenting might reduce no-reflow and salvage myocardium in primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). No-reflow is associated with adverse outcomes in STEMI. A prospective single center randomized controlled proof-of-concept trial in reperfused STEMI patients with ≥ 1 risk factors for no-reflow. Randomization ...
Niu J M JM Department of Cardiology, Laiwu People's Hospital, Laiwu, Shandong, - - 2014
B-type natriuretic peptide (BNP) is widely used in the treatment of early-stage heart failure and coronary heart disease. In this study, the association of plasma BNP concentration with myocardial infarct (MI) size in patients with acute myocardial infarction (AMI) was investigated. Eighty patients with AMI were enrolled in the MI ...
Utriainen Karri T KT Turku University Hospital, - - 2014
Obstructive sleep apnoea (OSA) is associated with atherosclerosis and cardiovascular events. Peripheral arterial disease (PAD) represents severe atherosclerosis with a high mortality after vascular surgery. The role of OSA in the prognosis of these patients is not yet established.84 patients (aged 67±9 years) scheduled for sub-inguinal surgical revascularisation were enrolled ...
Teng Zhongzhao Z 1Department of Radiology; Department of Engineering, University of Cambridge, United - - 2014
-Atherosclerotic plaques underlying most myocardial infarctions have thin fibrous caps and large necrotic cores; however these features alone do not reliably identify plaques that rupture. Rupture occurs when plaque structural stress (PSS) exceeds mechanical strength. We examined whether PSS could be calculated in vivo based on virtual histology intravascular ultrasound ...
Zhang Yao-Jun YJ Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Erasmus Medical Center, Rotterdam, The - - 2014
Everolimus-eluting stent (EES) are considered to have better clinical outcomes than other rapamycin derivative-eluting stents; however, the individual trials may not have sufficient power to prove it. This meta-analysis aimed to compare clinical outcomes of EES against other rapamycin derivative-eluting stents. We searched Medline, the Cochrane Library, and other internet ...
Kishimoto Ichiro I Department of Endocrinology and Metabolism, National Cerebral and Cardiovascular Center, Osaka, Japan. Electronic address: - - 2014
Diabetes is a major risk factor for heart failure (HF). We examined whether baseline HbA1c level predicts HF incidence independent of other HF risk factors, including baseline cardiac structural and functional abnormalities. In patients with type 2 diabetes, multivariable Cox regression models were constructed to examine the independent association between ...
Bligaard Niels - - 2014
Abstract Objective. Millions of patients were treated with the sirolimus-eluting Cypher™ and the paclitaxel-eluting Taxus™ coronary stents with potential late occurring increase in event rates. Therefore, the long-term outcome follow up is of major clinical interest. Design. In total, 2.098 unselected patients with ST-segment elevation myocardial infarction (STEMI), non-STEMI, stable ...
Micovic Slobodan S Department of Cardiac Surgery, Dedinje Cardiovascular Institute, University School of Medicine, Belgrade, - - 2014
Concomitant carotid and cardiac surgery carries an increased perioperative morbidity and mortality risk. Whether the hybrid procedure of carotid artery stenting (CAS) and coronary bypass surgery decreases the risk of stroke and other complications is still unknown. The aim of this study was to assess early outcomes after simultaneous hybrid ...
Okin Peter M PM Greenberg Division of Cardiology, Weill Cornell Medical College, New York, New - - 2014
Blacks have a higher prevalence of risk factors for atrial fibrillation (AF), such as hypertension, obesity, and heart failure, than nonblacks. Although population-based studies have demonstrated a lower prevalence and incidence of AF in blacks, the relationship of incident AF to race among hypertensive patients undergoing blood pressure lowering has ...
Pauriah Maheshwar M Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, , Dundee, - - 2014
To determine all-cause mortality in patients with a first myocardial infarct who were treated with simvastatin compared with high-potency statin and simvastatin/ezetimibe combination. Despite statin use, residual cardiovascular risk remains. Therapeutic options include more potent statins or addition of ezetimibe. There is no clinical outcome data on the use of ...
Raja Shahzad G SG From the Departments of *Cardiac Surgery, and †Quality and Safety, Harefield Hospital, London, - - 2014
Despite increasing recognition of the benefits of off-pump coronary artery bypass grafting (CABG), concerns persist regarding its impact on long-term mortality and freedom from reintervention. In this study, we assessed the impact of off-pump CABG on long-term outcomes. From January 2002 to December 2002, a total of 307 consecutive patients ...
Zhang Jiayin J From the Departments of Radiology (J.Z., Y.L., M.L.) and Cardiology (J.P., Z.L.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Rd, Shanghai 200233, - - 2014
Purpose To assess the correlation between the filling pattern of distal coronary vessels in patients with chronic total occlusion (CTO) observed at coronary computed tomographic (CT) angiography and the extent of downstream myocardial infarction (MI). Materials and Methods All patients gave written informed consent, and the institutional review board approved ...
Vujcic I I Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Visegradska 26a, 11000, Belgrade, Serbia, - - 2014
Living alone has been associated with higher risk of acute coronary syndrome in general population, but there are no consistent findings about its effect on prognosis after acute myocardial infarction (AMI). To analyse the relationships between living alone and other risk factors at baseline and long-term survival after AMI. One ...
Lee Park Kay K Center for Outcomes Research, University of Massachusetts Medical School, Worcester, - - 2014
Current guidelines recommend early oral beta-blocker administration in the management of acute coronary syndromes for patients who are not at high risk of complications. Data from patients enrolled between 2000 and 2007 in the Global Registry of Acute Coronary Events (GRACE) were used to evaluate hospital outcomes in three cohorts ...
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