Search Results
Results 551 - 600 of 3722
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de Waha Suzanne S University of Leipzig, Leipzig, - - 2014
Current ST-elevation myocardial infarction (STEMI) guidelines recommend initiation of clopidogrel treatment as early as possible before angiography, based on pharmacokinetic and positive registry data. However, the mechanisms of the beneficial effect of clopidogrel pretreatment are unclear. Aim of this study was to investigate the impact of upstream clopidogrel on infarct ...
Cansel Mehmet M Department of Cardiology, Faculty of Medicine, İnönü University; Malatya-Turkey. - - 2014
Ramadan fasting is one of the five fundamental rituals of Islam. Heart rate variability (HRV) is an independent predictor of increased mortality of patients with myocardial infarction and congestive heart failure. Although many patients in this region fast once a year, the effects of fasting on the HRV, which has ...
Kreutz Rolf P RP Krannert Institute of Cardiology, Indiana University School of Medicine, 1800 N. Capitol Ave, ME-400, Indianapolis, IN, 46202, USA, - - 2014
Factor XIII (FXIII) is necessary for cross linking of fibrin strands and generation of stable fibrin clot. FXIII Val34Leu is a common genetic single nucleotide polymorphism that has been associated with accelerated fibrin stabilization and reduced rate of fibrinolysis. The contribution of Val34Leu to long term risk of recurrent myocardial ...
Krishnasamy Rathika R Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, - - 2014
Left ventricular (LV) systolic dysfunction is an important predictor of cardiovascular death. Global longitudinal strain (GLS) is a widely available echocardiographic technique proven to be more sensitive than conventional ejection fraction (EF) in detecting subtle changes in LV function. However, the prognostic value of GLS in patients with chronic kidney ...
Kronborg Mads B MB Department of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, DK-8200 Aarhus, - - 2014
To compare left ventricular function after a long-term His or para-His pacing (HP) and right ventricular septal pacing (RVSP) in patients with atrioventricular block (AVB).METHODS AND RESULTS: We included consecutive patients with AVB, a narrow QRS < 120 ms, and a preserved left ventricular ejection fraction (LVEF) >0.40, in a ...
Mahaffey Kenneth W KW Duke Clinical Research Institute, Duke University, Durham, North Carolina; Department of Medicine, Stanford University, Stanford, California. Electronic address: - - 2014
This study reports the treatment effect of ticagrelor on myocardial infarction (MI) and the strategy for and impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial. In PLATO, ticagrelor reduced cardiovascular death, MI, or stroke in patients with acute coronary syndromes (ACS). A clinical events committee ...
Généreux Philippe P New York-Presbyterian Hospital and Columbia University Medical Center, New York, NY; Cardiovascular Research Foundation, New York, NY; Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montréal, Québec, - - 2014
We sought to determine the frequency and impact of coronary calcification among patients undergoing PCI for ACS. Small studies in patients with stable coronary artery disease have suggested a worse prognosis after percutaneous coronary intervention (PCI) of calcified compared to non-calcified lesions. Little is known about the impact of coronary ...
Ernande Laura L Service des Explorations Fonctionnelles Cardiovasculaires & Centre d'Investigation Clinique, Louis Pradel Hospital, Lyon, France; INSERM U955, Team 8, Faculté de Médecine de Créteil, Institut Mondor de Recherche Biomédicale, Université Paris-Est Créteil, Créteil, - - 2014
In normal subjects, left ventricular (LV) dimensions have been shown to decrease over time, while wall thickness is increasing. The aim of this study was to investigate LV remodeling in a cohort of patients with type 2 diabetes mellitus during a 3-year follow-up period and its potential association with decreased ...
Hannan Edward L EL University at Albany, State University of New York, Albany, New York. Electronic address: - - 2014
The goal of this study was to determine the utilization and outcomes for radial access for percutaneous coronary intervention (PCI) for ST-segment elevation acute myocardial infarction (STEMI) in common practice. Radial access for PCI has been studied considerably, but mostly in clinical trials. All patients undergoing PCI for STEMI in ...
Kobayashi Junpei J Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, - - 2014
Pontine infarcts can be classified into four regions based on the vascular anatomy: anteromedial, anterolateral, lateral and posterior. The purpose of this study was to determine if different etiological mechanisms are responsible for these four types of pontine infarcts. We studied consecutive patients within 7days of symptom onset who had ...
Akgun Taylan - - 2014
Objectives: The SYNTAX score (SXscore) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on the location and complexity of each lesion. The aim of this study was to evaluate whether the SXscore is an independent predictor of long-term cardiovascular outcomes in patients ...
Kim Hack-Lyoung HL Cardiovascular Center, Seoul National University Boramae Medical Center, Seoul, - - 2014
This study was conducted to investigate the incremental prognostic value of sequential use of single-photon emission computed tomography (SPECT) and coronary computed tomography angiography (CCTA) in patients with suspected coronary artery disease (CAD). A total of 1295 patients with suspected CAD who underwent both CCTA and SPECT within 90 days ...
Kolettis Theofilos M TM Department of Cardiology, University of Ioannina, Ioannina, Greece; Cardiovascular Research Institute, Ioannina and Athens, Greece. Electronic address: - - 2014
We investigated the role of endothelin-B receptors on sympathetic activation originating from the adrenal gland or from the myocardium and its impact on arrhythmogenesis during acute myocardial infarction. We studied two groups of rats (n=120, 284±2g), namely wild-type and ETB-deficient. Myocardial infarction was induced by permanent ligation of the left ...
Santos Ana Rita AR Serviço de Cardiologia, Hospital do Espírito Santo, Évora, Portugal. Electronic address: - - 2014
Multivessel disease in ST-elevation myocardial infarction (STEMI) is associated with a worse prognosis. A multivessel approach at the time of primary percutaneous coronary intervention (PCI) is the subject of debate. To assess the impact of a multivessel approach on in-hospital morbidity and mortality in patients with STEMI undergoing primary PCI. ...
Motwani Manish M Multidisciplinary Cardiovascular Research Centre & The Division of Cardiovascular and Diabetes Research, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds LS2 9JT, - - 2014
This study compared the myocardial ischaemic burden (MIB) in patients with angiographic three-vessel coronary artery disease (3VD) using high-resolution and standard-resolution myocardial perfusion cardiovascular magnetic resonance (perfusion CMR) imaging. One hundred and five patients undergoing coronary angiography had two separate stress/rest perfusion CMR studies, one with standard-resolution (2.5 mm in-plane) ...
Lee Yasuharu Y Division of Cardiology, Osaka Rosai Hospital. 1179-3, Nagasone-cho, Sakai-city, Osaka 591-8025, Japan. - - 2014
Percutaneous coronary intervention (PCI) for severe calcified lesions is still challenging, and there are few studies of drug-eluting stent (DES) implantation for severe calcified lesions, especially regarding long-term results and hemodialysis patients. The study purpose was to clarify the factors, including DES strut thickness, that affect the long-term outcome of ...
Jiang Meng M Department of Cardiology, Renji Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China 200127. - - 2014
We aimed to determine the best time period for an early invasive intervention in non-ST elevation acute coronary syndrome (NSTEACS) patients. Studies assessing the timing of percutaneous coronary intervention (PCI) in patients with NSTEACS have failed to generate a consensus on when PCI should be performed in such patients. Literature ...
Hussain Sajjad S Department of Cardiology, Armed Forces Institute of Cardiology, National Institute of Heart Diseases, - - 2014
Objective: To study the effect of trans-radial approach (TRA) on achievement of a door-to-balloon time (DBT) of ² 90 minutes in primary PCI percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). Study Design: Case series. Place and Duration of Study: Armed Forces Institute of Cardiology - National Institute of ...
Kalavrouziotis Dimitri D Department of Thoracic and Cardiovascular Surgery, , Cleveland Clinic, - - 2014
The incidence of percutaneous lead failure among patients supported with a HeartMate II left ventricular assist device is unknown. All HeartMate II left ventricular assist device driveline dysfunctions reported to Thoratec Corporation were retrospectively reviewed. The location and severity of driveline failures and their association with adverse clinical outcomes were ...
Mujarić Ekrema E 1Department of Internal Medicine, Cantonal Hospital Zenica, 2Department of Internal Medicine, General Hospital Tešanj, 3Department of Anesthesiology and Intensive Care, Cantonal Hospital Zenica, 4Department of Surgery, Cantonal Hospital Zenica, 5Department of Laboratory Diagnostics, University Clinic Tuzla, 6Department of Gantroenterohepatology, University Clinical Center, Sarajevo; Bosnia and - - 2014
Aim To analyze a change of level of nautriuretic peptide (NT pro- BNP) caused by stress distension of myocardial wall in cases of acute myocardial infarction (AIM), as a possible predictor of early heart failure. Methods Patients with myocardial infarction were followed up. Standard clinical and laboratory examination, including NT ...
Huang Shao-Hong SH Department of Cardiothoracic Surgery, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, China, - - 2014
Intracellular calcium overload is a key factor for myocardial ischemia reperfusion injury (IR). However, there was no report for interstitial calcium concentration dynamics. We investigated the interstitial calcium dynamics in rat myocardial IR model in vivo. A microdialysis system was involved, and the time delay of the system and recovery ...
Brenner Roman R Division of Cardiology, Kantonsspital St. Gallen, Rorschacherstrasse 95, CH-9007 St. Gallen, - - 2014
Aim: Inflammatory processes may contribute to myocardial ischemia/reperfusion injury after myocardial infarction (MI). We aimed to evaluate the predictive value of complement factor concentrations for the occurrence of post-MI left ventricular (LV) dysfunction. Patients & methods: Fifty-five patients with acute MI were included. Complement factors and CRP were assessed at ...
Dores Hélder H 1 Hospital de Santa Cruz, Lisbon, Portugal ; 2 Hospital de Faro, Faro, Portugal ; 3 Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal ; 4 Hospital de São Bernardo, Setúbal, - - 2014
Although the proven efficacy of evidence-based therapy in patients with cardiovascular diseases, the recommendations are not always instituted. We aimed to analyse the compliance of non-ST-elevation acute coronary syndrome (NSTE-ACS) patients with treatment guidelines and to assess the impact of these measures in hospital death during the index hospitalization. All ...
Abbasnezhad Mohsen M Department of Cardiology, Tabriz University of Medical Sciences, Tabriz, IR - - 2014
Chest pain is one of the most common causes of the admission to the emergency departments. It, however, can be due to numerous diseases some of which are life threatening. In the current study, we evaluated the prognostic value of TIMI (Thrombolysis in Myocardial Infarction) and Modified TIMI risk scores ...
Stergiopoulos Kathleen K Division of Cardiovascular Medicine, Department of Medicine, State University of New York-Stony Brook School of Medicine, Stony - - 2014
Myocardial ischemia in patients with stable coronary artery disease (CAD) has been repeatedly associated with impaired survival. However, it is unclear if revascularization with percutaneous coronary intervention (PCI) to relieve ischemia improves outcomes compared with medical therapy (MT). The objective of this study was to compare the effect of PCI ...
Bouhajja Bechir - - 2014
Background: Fibrinolysis during ST elevation myocardial infarction (STEMI) is feasible in the emergency departments (ED), and this reduces the delay from first medical contact to coronary reperfusion. The aim of the study is to: 1) Evaluate fibrinolysis with streptokinase (SK) in STEMI admitted to the ED. 2) identify clinical criteria ...
Sipahi Ilke I Department of Cardiology, Acibadem University Medical School, Istanbul, Turkey2Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, - - 2014
Recent trials of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) for multivessel disease were not designed to detect a difference in mortality and therefore were underpowered for this outcome. Consequently, the comparative effects of these 2 revascularization methods on long-term mortality are still unclear. In the absence ...
Bellam Naveen N Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Road NE, Room 529, Atlanta, GA, 30324, - - 2014
An impaired chronotropic response to exercise is an accepted risk marker but the relationship between heart rate reserve (HRR) with pharmacologic stress is less well-established. The primary aim of this analysis was to evaluate the prognostic significance of HRR in patients undergoing rest/stress myocardial perfusion positron emission tomography (PET) in ...
Liebetrau Christoph C Department of Cardiology, Kerckhoff Heart and Thorax Center, , Bad Nauheim, - - 2014
To determine the release kinetics of different biomarkers with potential as novel early ischaemic biomarkers in patients with acute coronary syndrome (ACS); it is difficult to establish the detailed release kinetics in patients with acute myocardial infarction (AMI). We analysed the release kinetics of soluble fms-like tyrosine kinase (sFlt-1), ischaemia ...
De Servi Stefano S aCardiovascular Department, AO 'Ospedale Civile', Legnano bDivision of Cardiology, Manzoni Hospital, Lecco cDivision of Cardiology, Misericordia e Dolce Hospital, Prato dDivision of Cardiology, AO 'Villa Scassi', Genova eDivision of Cardiology, Ospedali Riuniti, Treviglio fCardiology Unit, Spedali Civili, Brescia gDivision of Cardiology, St Antonio Abate Hospital, Gallarate hDivision of Cardiology, Desio Hospital, Desio iDivision of Cardiology, Terni Hospital, Terni jLaboratory Unit, AO 'Ospedale Civile' di Legnano, - - 2014
Serum cystatin C (Cys-C), a good marker of renal function, predicts prognosis in non-ST-elevation acute coronary syndromes (NSTE-ACS). However, no data are available on the time course of Cys-C values after discharge. In this study, Cys-C was measured during admission (ACS sample) and 6 weeks after discharge, and was correlated ...
Jochmann Nicoline - - 2014
Experimental data suggests that exclusive heart rate reduction with ivabradine is associated with the amelioration of the endothelial function. Since it is presently unknown whether this also applies to humans, the aim of this pilot study was to investigate whether heart rate reduction with ivabradine modulates the endothelial function in ...
Taniwaki Masanori M Bern University Hospital, Bern, - - 2014
To investigate 4-year outcomes and predictors of repeat revascularization in patients treated with Resolute™ zotarolimus-eluting stent (R-ZES) and XIENCE V™ everolimus-eluting stent (EES) in the RESOLUTE All Comers trial. Data on long-term outcomes of new generation drug-eluting stents are limited, and predictors of repeat revascularization due to restenosis and/or progression ...
Figueras Jaume J Unitat Coronària, Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Electronic address: - - 2014
Occurrence of moderate-to-severe pericardial effusion (PE; ≥10 mm), cardiac tamponade (CT), and sudden electromechanical dissociation (EMD) was investigated in 4,361 patients with ST-elevation myocardial infarction from 1993 to 2011 in 3 different periods: 1993 to 2000 (n: 1,488); 2001 to 2008 (n: 1,844); and 2009 to 2011 (n: 1,014). Their predictors, ...
Moss Travis J TJ Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, - - 2014
Because alcohol septal ablation (ASA) for the treatment of symptomatic hypertrophic cardiomyopathy (HC) with left ventricular (LV) outflow tract (LVOT) obstruction results in a myocardial infarct of up to 10% of ventricular mass, LV systolic function could decline over time. We evaluated LV function during longitudinal follow-up in a cohort ...
Goebel Björn B 1st Department of Medicine, Division of Cardiology, University Hospital of Jena, Erlanger Allee 101, 07740, Jena, Germany, - - 2014
The aim of this prospective study was to assess the value of speckle tracking echocardiographic (2D-STE) parameters to predict response to heart failure therapy in patients with dilated cardiomyopathy (DCM). Eighty-seven patients (mean age 51 ± 13 years) with DCM, defined as ejection fraction (EF) <45 %, left ventricular (LV) end-diastolic diameter >112 % of ...
Lupi Alessandro A Hospital Cardiology, "Maggiore della Carità" Hospital, Novara, - - 2014
Objectives: to perform an updated meta-analysis comparing biodegradable (BP-DES) and durable (DP-DES) polymer drug eluting stents. Background: BP-DES have been suggested to reduce late stent thrombosis (LST) rates as compared to 1(st) generation DP-DES. Recently, 2(nd) generation DP-DES have replaced older DES, but comparisons of these stents with BP-DES has ...
Hyler Stefan S The Intervention Centre, Rikshospitalet, Oslo University Hospital, Oslo, - - 2014
Preservation of left ventricular (LV) function is crucial for a beneficial outcome in high-risk patients undergoing cardiac surgery. The present study evaluated a motion sensor (accelerometer) for continuous monitoring of LV performance during changes in global and regional LV function. In 11 pigs, an accelerometer was sutured to the epicardium ...
Rhee June-Wha JW Department of Medicine, Stanford University Medical Center, Stanford, - - 2014
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular events following acute coronary syndrome (ACS). The underlying pathobiology and optimal treatments for this population continue to be evaluated. Patients with CKD will receive fewer evidence-based therapies and experience high rates of adverse cardiovascular events in both the ...
Kim Sung Eun SE Department of Internal Medicine, Kangdong Sacred Heart Hospital, Seoul, - - 2014
The non-invasive differentiation of ischemic and non-ischemic acute heart failure (AHF) not resulting from acute myocardial infarction is difficult and has therapeutic and prognostic implications. The aim of this study was to assess whether plasma B-type natriuretic peptide (BNP) can identify ischemic etiology in patients with stage 4-5 chronic kidney ...
Arini Pedro David PD Argentine Institute of Mathematics, 'Alberto P. Calderón' (CONICET), Saavedra 15, C1083ACA, Buenos Aires, Argentina, - - 2014
In this work, we studied the evolution of different electrocardiogram (ECG) indices of ventricular repolarization dispersion (VRD) during acute transmural myocardial ischemia in 95 patients undergoing percutaneous coronary intervention (PCI). We studied both temporal indices of VRD (T-VRD), based on the time intervals of the ECG wave, and spatial indices ...
Poller Wolfram C WC Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie (CCM), Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany, - - 2014
Cardiac resynchronization therapy (CRT) is an effective treatment for a large subgroup of chronic heart failure patients. Various attempts to improve the high non-responder rate of 30 % by preoperative asynchrony assessment have failed. We hypothesized that superior response to CRT is correlated with greater acute reduction of asynchrony and that ...
Akin I I Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Deutschland, - - 2014
Drug-eluting stents (DES) have substantially reduced target vessel revascularization (TVR) after percutaneous coronary interventions. Risk factors for clinical events need to be redefined with this treatment option. In the prospective DES.DE registry, baseline clinical and angiographic characteristics as well as in-hospital and follow-up events were recorded for all enrolled patients. ...
Ozkan Gülsüm G Department of Nephrology, Faculty of Medicine, Karadeniz Technical University; Trabzon-Turkey. - - 2014
More cardiovascular events are seen in nephrotic syndrome (NS) patients than in the normal population. Fragmented QRS (fQRS) includes various RSR' patterns with different morphologies of the QRS complexes with or without the Q wave on a resting 12-lead ECG. A relationship between the presence of fQRS and myocardial function ...
Lamberts Morten M Copenhagen University Hospital Gentofte, Hellerup, - - 2014
Optimal long-term antithrombotic treatment of patients with coexisting atrial fibrillation (AF) and stable coronary artery disease (CAD) is unresolved and commonly a single antiplatelet agent is added to oral anticoagulation. We investigated the effectiveness and safety of adding antiplatelet therapy to vitamin K antagonist (VKA) in AF patents with stable ...
Erlinge David D Department of Cardiology, Lund University, 221 85, Lund, Sweden. Electronic address: - - 2014
Hypothermia has been reported to reduce infarct size (IS) in patients with ST segment elevation myocardial infarction (STEMI). We aimed to confirm the cardioprotective effects of hypothermia using a combination of cold saline and endovascular cooling. In a multi-center study, 120 patients with STEMI (<6 hours) planned to undergo percutaneous ...
Khan Abdur Rahman AR Division of Cardiovascular Medicine, Department of Internal Medicine, University of Toledo Medical Center, Toledo, OH, - - 2014
The objective of this study is to evaluate the prevalence, geometric patterns, and factors associated with left ventricular remodeling in patients with renal artery stenosis (RAS). Demographic, clinical, and echocardiographic data were assessed in 77 patients with RAS prior to endovascular stenting. The left ventricular mass index (LVMI) and relative ...
Jiang Cuihua C Laboratory of Translational Medicine, Jiangsu Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu Province, - - 2014
The aim of this study was to investigate the necrosis avid agent hypericin as a potential indicator for determination of myocardial infarction (MI). Male Sprague-Dawley rats (n=30) weighing 350±20 g were subjected to acute reperfused MI. Animals were divided into 4 groups (n=6), in which hypericin was intravenously injected at ...
Lupi-Herrera Eulo E Eulo Lupi-Herrera, The American British Cowdray Medical Center I.A.P., Mexico City 14080, - - 2014
To investigate the impact of primary reperfusion therapy (RT) on early and late mortality in acute right ventricular infarction (RVI). RVI patients (n = 679) were prospectively classified as without right ventricular failure (RVF) (class A, n = 425, 64%), with RVF (class B, n = 158, 24%) or with ...
Fayssoil Abdallah A Réanimation médicale, Hôpital Raymond Poincaré (AP-HP), Université de Versailles SQY, 104 boulevard Raymond Poincaré, 92380, Garches, France, - - 2014
Sarcoglycanopathies are autosomic recessive muscular dystrophies, secondary to mutations of the sarcoglycan complex. Heart can be involved in sarcoglycanopathies. We sought to analyse left ventricular function in patients with alpha-sarcoglycanopathy and gamma-sarcoglycanopathy. We conducted a retrospective study that aimed to analyse clinical and echocardiographic data of patients with sarcoglycanopathies. Our ...
Nishi Hiroyuki H Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, - - 2014
We describe the first clinical experiences in Japan with the HeartWare ventricular assist device (HVAD: HeartWare Inc., Miami Lakes, FL, USA) in patients awaiting heart transplantation. Nine patients (6 males, 3 females; mean 33.5 ± 7.8 years; New York Heart Association class III or IV) received the HVAD as a bridge to transplantation ...
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