Search Results
Results 501 - 550 of 3215
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Teraguchi Ikuko - - 2013
Background: It remains unclear whether glycemic fluctuation immediately after acute myocardial infarction (AMI) can affect myocardial damage. This study investigated the impact of glucose fluctuation on myocardial salvage following successful recanalization of primary AMI. Methods and Results: A total of 36 consecutive patients with AMI were studied. Glycemic variability, as indicated by ...
Kubo Shunsuke - - 2013
Background: Differences in long-term outcome between early stent thrombosis (EST), late stent thrombosis (LST), and very late stent thrombosis (VLST) are unknown. Methods and Results: A total of 152 patients who had undergone percutaneous coronary intervention for stent thrombosis between January 2001 and October 2011 were enrolled, and the clinical outcome compared ...
Parashar Susmita - - 2013
Atrial fibrillation (AF) is an independent predictor of mortality after acute myocardial infarction (AMI). We analyzed the relation between biomarkers linked to myocardial stretch (NT-pro-brain natriuretic peptide [NT-proBNP]), myocardial damage (Troponin-T [TnT]), and inflammation (high-sensitivity C-reactive protein [hs-CRP]) and new-onset AF during AMI to identify patients at high risk for ...
Delise Pietro - - 2013
The long-term outcome of athletes with frequent ventricular premature complexes (VPCs) and apparently normal heart has not been fully clarified. To evaluate the clinical and prognostic significance of VPCs and the influence of continuing sports activity during follow-up, we studied 120 healthy athletes (96 men; median age 16 years) in whom ...
Truong Thang V - - 2013
Left ventricular assist devices (LVADs) are blood pumps that augment the function of the failing heart to improve perfusion, resulting in improved survival. For LVADs to effectively unload the left ventricle, the inflow cannula (IC) should be unobstructed and ideally aligned with the heart's mitral valve (MV). We examined IC ...
Park Ji Young - - 2013
Purpose: High sensitive C-reactive protein (hs CRP) is well known as a strong risk factor of cardiovascular disease (CVD). The aim of this study is to evaluate the impact of elevated hs CRP on coronary artery spasm (CAS) as assessed by intracoronary acetylcholine (ACh) provocation test. Materials and Methods: A ...
Ernst Aleksander - - 2013
The objective of this study was to determine the long-term efficacy and dynamics of systolic and diastolic luminal changes within the bridged segments of coronary arteries after intracoronary stenting with drug-eluting stent (DES) in patients (pts) with symptomatic myocardial bridging (SMB) in the absence of coronary atherosclerosis. Although myocardial bridging ...
Radovanovic Dragana - - 2013
This study aimed to assess the impact of individual comorbid conditions as well as the weight assignment, predictive properties and discriminating power of the Charlson Comorbidity Index (CCI) on outcome in patients with acute coronary syndrome (ACS). A prospective multicentre observational study (AMIS Plus Registry) from 69 Swiss hospitals with ...
Joyce Emer - - 2013
-Myocardial infarct size is a major determinant of left ventricular (LV) remodeling after ST-segment elevation myocardial infarction (STEMI). We evaluated whether LV global longitudinal strain (GLS), proposed as a novel marker of infarct size, is associated with 3- and 6-month LV dilatation after STEMI. -In first STEMI patients treated with ...
Mlakar Polona - - 2013
Oxidative stress is an important nonclassical risk factor for myocardial infarction (MI), and thus, it seems extremely important to recognize factors that effectively reduce it. The aim of our study was to explore possible influences of short-term cardiac rehabilitation (CR) of only 2 weeks in duration on oxidative stress in ...
Hu Xiao-Ying - - 2013
Ventricular septal rupture (VSR) remains an infrequent but devastating complication of acute myocardial infarction (AMI). The best time to undergo surgical repair is controversial and there is currently no risk stratification for patients with VSR to guide treatment. The purpose of this study was to review the clinical outcomes of ...
Lin Lian-Yu - - 2013
This study evaluated whether the conductive channel (CC) identified by late gadolinium enhanced-cardiac magnetic resonance (LGE-CMR) is associated with ventricular tachycardia (VT) in patients with systolic heart failure (HF). One recent study demonstrated that the CC formed by heterogeneous tissue within the core scar could be detected by LGE-CMR and ...
Lujinović Almira - - 2013
Although some myocardial bridges can be asymptomatic, their presence often causes coronary disease either through direct compression of the "tunnel" segment or through stimulation and accelerated development of atherosclerosis in the segment proximally to the myocardial bridge. The studied material contained 30 human hearts received from the Department of Anatomy. ...
Martínez-Sellés M M Hospital General Universitario Gregorio Marañón, Madrid, Spain, - - 2013
The influence of new-onset atrial fibrillation (AF) on the long-term prognosis of nonagenarians who survive acute myocardial infarction (AMI) has not been demonstrated. Our aim was to study the association between new-onset AF and long-term prognosis of nonagenarians who survive AMI. From a total of 96 patients aged ≥89 years admitted ...
Yoon Hyun Ju HJ The Heart Center of Chonnam National University Hospital, Korea Cardiovascular Stent Research Institute of Chonnam National University, Gwangju, - - 2013
The purpose of this study is to identify the prevalence of progressive dilation in patients with acute myocardial infarction (AMI) combined with heart failure (HF) and determine the prognostic significance and associated factors with a geometric change of an infarcted heart. A total of 1310 AMI patients with HF (63.9±12.5 ...
Mulay Dnyaneshwar V DV Department of Medicine, Government Medical College, Aurangabad 431001, Maharashtra, India. Electronic address: - - 2013
ECG on admission has been used in predicting prognosis and risk stratification in ST segment elevation acute myocardial infarction (STEMI). To analyze the admission ECG in STEMI based on abnormality observed in terminal portion of QRS and its correlation to hospital mortality. 160 consecutive patients of STEMI were classified into ...
Mahendra Jaideep J Department of Periodontics, Meenakshi Ammal Dental College and Hospital, Chennai, - - 2013
The objective of the present study was to detect the presence of specific periodontopathogenic bacteria in the coronary plaque of patients with coronary artery disease and to find out the significant association between the periodontal status and the presence of pathogenic bacteria in the coronary plaque. The study population consisted ...
Sood Nitesh - - 2013
The aim of the present study was to assess a possible association between myocardial substrate, implantable cardioverter defibrillator (ICD) shocks, and subsequent mortality. Within the multicentre automatic defibrillator implantation trial-cardiac resynchronization therapy (MADIT-CRT) population (n = 1790), we investigated the association between myocardial substrate, ICD shocks and subsequent mortality using ...
Liu Zhonglin - - 2013
Soluble tumor necrosis factor (TNF) receptor-2 (TNFR2) and interleukin-1 receptor antagonist (IL-1ra) were fused to the Fc portion of IgG1 using recombinant DNA technology. The resulting dual-domain cytokine ligand, TNFR2-Fc-IL-1ra, specifically binds to TNF and to the type I IL-1 receptor (IL-1RI). This study was designed to characterize the kinetic ...
Kim Ung - - 2013
We aimed comparing two-year clinical outcomes of the Everolimus-Eluting Promus and Paclitaxel-Eluting TAXUS Liberte stents used in routine clinical practice. Patients with objective evidence of ischemia and coronary artery disease eligible for PCI were prospectively randomized to everolimus-eluting stent (EES) or paclitaxel-eluting stent (PES) groups. The primary end-point was ischemia-driven ...
Brener Sorin J - - 2013
We compared the outcomes of patients treated with everolimus-eluting stents (EES) versus paclitaxel-eluting stents (PES) at 3 years from the large-scale randomized SPIRIT IV trial. SPIRIT IV is the largest randomized trial comparing the outcomes of EES and PES. The present report represents the final long-term follow-up analysis from this ...
Carlsen Esben A EA Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: - - 2013
The reduction of left ventricular ejection fraction (LVEF) following ST-segment elevation myocardial infarction (STEMI) is a result of infarcted myocardium and may involve dysfunctional but viable myocardium. An index that may quantitatively determine whether LVEF is reduced beyond the expected value when considering only infarct size (IS) has previously been ...
Dahl Jordi S - - 2013
-In aortic stenosis (AS), the occurrence of heart failure symptoms does not always correlate with severity of valve stenosis and left ventricular (LV) function. Therefore we tested the hypothesis that symptomatic AS patients have impaired diastolic, longitudinal systolic function and left atrial (LA) dilatation compared to asymptomatic patients. -In a ...
Barasch Eddy - - 2013
Background: Many symptomatic patients with severe aortic stenosis (AS) and preserved left ventricular ejection fraction (LVEF) are denied surgery and have a grim prognosis with medical management. Methods and Results: Between 2003 and 2012, among 550 patients with severe isolated AS and preserved LVEF on transthoracic echocardiography, 241 did not undergo aortic ...
Nazif Tamim M - - 2013
Cardiac conduction disturbances, including a left bundle branch block (LBBB), occur frequently following transcatheter aortic valve replacement (TAVR) and may be associated with adverse clinical events. This analysis examines the incidence and implications of new onset, persistent LBBB in patients undergoing TAVR with a balloon-expandable valve. Patients undergoing TAVR in ...
Sheu Jiunn-Jye - - 2013
This study investigated the association between innate immune reaction and myocardial damage after acute myocardial infarction (AMI) and anti-inflammatory role of tacrolimus in reducing infarct size. Male mini-pigs (n=18) were equally categorized into sham control (SC), untreated AMI (by ligation of left anterior descending coronary artery), and AMI-Tacrolimus (AMI-Tac) (0.5 ...
Erkol Ayhan - - 2013
Spontaneous early patency of infarct-related artery (IRA) on arrival for primary percutaneous coronary intervention is associated with better short- and long-term prognosis in patients with ST-segment elevation myocardial infarction (STEMI). We aimed to investigate whether the hemographic parameters on admission are associated with spontaneous IRA patency. This was a retrospective ...
Santamarta Elena - - 2013
Two population-based studies have found an increased prevalence of posterior circulation territory (PCT) infarct-like lesions in migraine, which seemed to increase with attack frequency. To determine whether chronic migraine (CM) patients are at increased risk of PCT infarct-like lesions. We prospectively obtained brain MRIs from adult women fulfilling CM criteria. ...
Koch Mette B - - 2013
Mortality from ischaemic heart disease (IHD) including acute myocardial infarction (AMI) in Denmark peaked around 1977, after which a marked decline has occurred as a result of decreasing incidence and increasing effect of treatment. IHD is a chronic, relapsing condition, and the effect of these changes on the prevalence of ...
Tanaka Ryoichi - - 2013
We explore the feasibility of coronary calcium subtraction computed tomography angiography (CCTA) in patients with high calcium scores using invasive coronary angiography as the gold standard. Eleven patients with calcium scores of >400 underwent CCTA using a subtraction protocol followed by invasive coronary angiography. In addition to standard reconstructions, subtracted ...
Ohlow Marc-Alexander - - 2013
Drug-eluting stents (DES) constitute a major achievement in preventing re-stenosis, concerns remain regarding the increased inflammatory responses associated with the polymers used. This analysis focuses on outcomes in patients receiving the polymer-free sirolimus-eluting stent system YUKON-Choice (Yukon-DES, Translumina, Germany). From 01/2006-09/2008 all patients receiving Yukon-DES (≥2.5 mm diameter) were prospectively ...
Shen Lan - - 2013
Prior studies have observed that smokers have paradoxically favorable 1-year mortality rates after acute coronary syndromes, but it is unknown whether this association extends to long-term outcomes and to older patients. We identified 38,628 patients aged ≥65 years participating in the CRUSADE Registry between February 2003 and December 2006 with ...
Lee Michael S - - 2013
We evaluated the safety and efficacy of low-dose heparin (40 IU/kg) for elective percutaneous coronary intervention (PCI). Current guidelines recommend a 70-100 IU/kg bolus of heparin for elective PCI, but this dose may be associated with increased bleeding risk. Low-dose heparin may have an advantage in this regard, but has not been ...
Karabay Can Y - - 2013
Nonalcoholic fatty liver disease (NAFLD) encompasses a disease spectrum ranging from simple steatosis to nonalcoholic steatohepatitis (NASH). We aimed to evaluate left ventricular (LV) systolic function using two-dimensional speckle-tracking echocardiography (2D-STE) in patients with NAFLD and to investigate whether any changes exist among the subgroups of NAFLD. We included 55 ...
Kruk Mariusz - - 2013
The purpose of the Occluded Artery Trial (OAT) Biomarker substudy was to evaluate the impact of infarct related artery (IRA) revascularization on serial levels of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) and dynamics of other biomarkers related to left ventricular remodeling, fibrosis and angiogenesis. Patients were eligible for OAT-Biomarker ...
de Chillou Christian C CHU de Nancy, Département de Cardiologie, Vandœuvre lès-Nancy, F-54500, France; INSERM-IADI, U947, Vandœuvre lès-Nancy, F-54500, France. Electronic address: - - 2013
Most post-infarct ventricular tachycardias (VT) are sustained by a reentrant mechanism. The 'protected isthmus' of the reentrant circuit is critical for the maintenance of VTs and the target for catheter ablation. Various techniques, based upon conventional electrophysiology and/or detailed 3D reconstruction of the VT circuit are used to unmask this ...
Shin Dong Il - - 2013
The prognostic impact of occluded culprit arteries in non-ST-elevation myocardial infarction (NSTEMI) patients beyond 12 months has not been investigated. The impact of occluded culprit arteries on a composite of cardiac death (CD), recurrent nonfatal MI (RMI), and target vessel revascularization (TVR) in patients who presented with NSTEMI was investigated ...
John Roy M - - 2013
Radiofrequency (RF) ablation of scar-mediated ventricular tachycardia is limited by the size of lesions achieved with conventional catheters. We examined the gross and histopathology characteristics of warm saline-enhanced radiofrequency ablation (SERF™) delivered to left ventricular (LV) infarction scars via a novel catheter employing an extendable infusion needle electrode. Yorkshire pigs ...
Hlatky Mark A MA Stanford University School of Medicine, Stanford, CA. Electronic address: - - 2014
Prognostic factors are usually evaluated by their statistical significance rather than by their clinical utility. Risk reclassification measures the extent to which a novel marker adds useful information to a prognostic model. The extent to which estimated glomerular filtration rate (eGFR) adds information about prognosis among patients with coronary heart ...
Guzik Przemyslaw - - 2013
Background: Heart rate asymmetry is caused by an unequal contribution of heart rate decelerations and accelerations to heart rate variability. This study evaluates the asymmetric properties of the variability of the AA, HH, VV, AH and HV intervals. Methods and Results: We recorded 50 1-min intracardiac ECG tracings from 10 patients (18-66 ...
Thorvaldsen Tonje - - 2013
To evaluate simple criteria for referral of patients from the general practitioner to a heart failure (HF) center BACKGROUND: In advanced HF, the criteria for heart transplantation (HTx), left ventricular assist device (LVAD) and palliative care are well known among HF specialists, but criteria for referral to an advanced HF ...
Palmerini Tullio - - 2013
We sought to investigate the relative safety and efficacy of bioabsorbable polymer (BP)-based biolimus-eluting stents (BES) vs durable-polymer (DP)-drug eluting stents (DES) and bare metal stents (BMS) by means of a network meta-analysis. Studies have suggested that BP-BES may reduce the risk of stent thrombosis (ST) and late adverse outcomes ...
Latib Azeem - - 2013
Stent underexpansion is a risk factor for in-stent restenosis and stent thrombosis. Existing techniques to optimize stent expansion are sometimes ineffective. The aim of this study was to evaluate the effectiveness and feasibility of Excimer Laser Coronary Angioplasty (ELCA) in improving stent expansion when high-pressure non-compliant balloon inflation was ineffective. ...
Fröhlich Georg M GM Cardiovascular Center, Cardiology and Cardiac Imaging, Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland; The Heart Hospital London, University College London, London, United - - 2013
It remains still unclear whether the use of modern noninvasive diagnostic modalities for evaluation of coronary artery disease (computed tomography coronary angiography (CTCA), nuclear myocardial perfusion imaging (MPI)) were able to change the "diagnostic yield" of invasive coronary angiography (ICA). The total number of ICA in the years 2000-2009 was ...
Szymanski Filip M - - 2013
Cardiovascular disease are the leading cause of death worldwide. One of the most important diseases in this group is myocardial infarction. According to the Universal Definition developed by the European Society of Cardiology (ESC) myocardial infarction is divided into five main types basing on its cause. Type 2 myocardial infarction ...
Cosansu Kahraman - - 2013
Apelin, is a novel endogenous peptide with inotropic and vasodilator properties. The aims of this study were to investigate the role of apelin in prognosis of acute coronary syndromes (ACS) and to assess the relationship between apelin and other diagnostic and prognostic markers. Seventy-six patients with ACS (mean age 62.1±10 ...
Prech Marek - - 2013
Studies on the treatment of patients with an acute ST-segment elevation myocardial infarction (STEMI) with primary percutaneous coronary intervention (PCI) showed a high rate of aborted MI despite a relatively long delay from the onset of symptoms to reperfusion. To assess predictors of aborted MI in patients undergoing primary PCI. ...
Sawant Abhishek C - - 2013
Several inflammation biomarkers have been implicated in the pathogenesis and prognosis of acute coronary syndromes (ACS). However, the prognostic role of the neutrophil-lymphocyte white cell interactive response to myocardial injury in predicting short and long-term mortality after ST elevation myocardial infarction (STEMI) remains poorly defined. We evaluated 250 consecutive STEMI ...
Shacham Yacov - - 2013
Diastolic dysfunction and elevated left ventricular (LV) filling pressure following acute myocardial infarction (AMI) are associated with adverse outcomes. Although time to reperfusion is a powerful prognostic marker following an AMI, little is known about its impact on diastolic function and LV filling pressure. We hypothesized that delayed time to ...
Kręcki Radosław - - 2013
Multivessel coronary artery disease (MCAD) is a common manifestation of advanced coronary atherosclerosis. The aim of this study was to determine clinical characteristics and long term follow up prognostic factors in patients with high risk, stable MCAD from a single institution. We include to the final analysis 270 patients with ...
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