Search Results
Results 451 - 500 of 3682
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Tisminetzky Mayra M Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, - - 2014
Although acute myocardial infarction (AMI) occurs primarily in the elderly, this disease also affects young adults. Few studies have, however, presented data on relatively young patients hospitalized with AMI. The objectives of this population-based study were to examine recent trends in the magnitude, clinical characteristics, management, and in-hospital and long-term ...
Wang Ji-Hong JH Department of Cardiology, Beijing An-Zhen Hospital, Capital Medical University, Beijing 100029, China ; Department of Cardiology, Beijing Ji-Shui-Tan Hospital, the 4th Clinical College of Peking University Health Science Center, Beijing 100035, - - 2014
To investigate the procedure characteristics and long term follow-up of percutaneous coronary intervention (PCI) for saphaneous vein graft (SVG) lesions in the elderly patients. From December 2005 to December 2011, 84 graft lesions were treated percutaneously. Seventeen were located at proximal anastomosis, 48 were located at SVG body, 19 were ...
Bureekam Sangrawee - - 2014
Anatomical left atrial enlargement is associated with significant cardiovascular morbidity and mortality, heart failure, stroke, atrial fibrillation and diastolic dysfunction. This concept is more pronounced in hypertensive population, who have an especially increased risk of LA enlargement from diastolic dysfunction when compared to the general population. However left atrial enlargement ...
Praipaisarnkit Kreangkrai - - 2014
Cardiovascular disease is leading cause of death in the world and third order in Thailand. A number of large-scale clinical trials have demonstrated that statins reduce cardiovascular morbidity and mortality. Nevertheless, in clinical practice less than 50% of these patients could achieve the LDL-C goal based on NCEP ATP III ...
Zeraati Fatemeh F Department of Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, - - 2014
The door-to-needle-time (DNT) is considered a standard time for scheduling thrombolysis for acute ST-segment elevation of myocardial infarction and this time can be reduced by minimizing the delay in starting thrombolytic treatment once the patient has reached to the hospital. This study was carried out on a sample of Iranian ...
Vasilj Mirjana - - 2014
We assessed the diagnostic efficacy of plasma Myeloperoxidasis (MPO) alone or in combination with cardiac troponin I (cTnI) for detecting ACS in patients presenting with chest pain initiating within 24 h before the hospital admission. In this prospective cohort study were included all respondents who have visited outpatient clinic of ...
Moran Andrew E AE Division of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY, - - 2014
Ischemic Heart Disease (IHD) was the leading cause of disease burden worldwide in 2010. The majority of IHD burden affected middle income regions. We hypothesized that IHD burden may vary among countries, even within the same broad geographic region. Disability-adjusted life years (DALYs) due to IHD were estimated at the ...
Lam Ming Kai MK Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The - - 2014
Aims: To investigate the prognostic value of coronary dominance for various adverse clinical events following the implantation of drug-eluting stents. Methods and results: We assessed two-year follow-up data of 1,387 patients from the randomised TWENTE trial. Based on the origin of the posterior descending coronary artery, coronary circulation was categorised ...
Räber Lorenz L Department of Cardiology, Bern University Hospital, Bern, - - 2014
Pathology studies have shown delayed arterial healing in culprit lesions of patients with acute coronary syndrome (ACS) compared with stable coronary artery disease (CAD) after placement of drug-eluting stents (DES). It is unknown whether similar differences exist in-vivo during long-term follow-up. Using optical coherence tomography (OCT), we assessed differences in ...
Auger Dominique D Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands; Department of Cardiology, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, - - 2014
Right ventricular apical (RVA) pacing may induce left ventricular (LV) dyssynchrony. The long-term prognostic implications of induction of LV dyssynchrony were retrospectively evaluated in a cohort of patients who underwent RVA pacing. A total of 169 patients (62±13 years, 69% male) with high RVA pacing burden were included. Echocardiographic evaluation ...
Wang Tom Kai Ming TK Green Lane Cardiovascular Service, Auckland City Hospital, New - - 2014
Cardiac troponins are the preferred biomarkers for diagnosing myocardial infarction (MI). High-sensitivity troponin T (hs-TnT) assays have increased sensitivity and enable more rapid diagnosis of infarction. We assessed the prognostic utility of admission hs-TnT to detect outcomes after primary angioplasty for ST-elevation/new left bundle branch block myocardial infarction (STEMI). Patients ...
Goo Ja-Jun JJ Department of Internal Medicine, Maryknoll Medical Center, Busan, - - 2014
With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-system (RAS) blockers, which are also used in a variety of cardiovascular disorders. This study evaluated the ...
Sherwood Matthew W MW Duke Clinical Research Institute, Durham, North - - 2014
Studies have shown variation in the use of red blood cell transfusion among patients with acute coronary syndromes. There are no definitive data for the efficacy of transfusion in improving outcomes, and concerning data exist about possible association with harm. Current transfusion practices in patients undergoing percutaneous coronary intervention (PCI) ...
Bamberg Fabian F Department of Clinical Radiology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 15, 81377, Munich, Germany, - - 2014
The purpose of the study is feasibility of dynamic CT perfusion imaging to detect and differentiate ischemic and infarcted myocardium in a large porcine model. 12 Country pigs completed either implantation of a 75 % luminal coronary stenosis in the left anterior descending coronary artery simulating ischemia or balloon-occlusion inducing infarction. ...
Tanındı Aslı - - 2014
Abstract Objectives: We investigate the association between non-invasively determined central pulse waveform characteristics and the extent and severity of coronary artery disease (CAD) in patients undergoing coronary angiography with the clinical diagnosis of CAD. Design: We included 145 consecutive patients with stable angina pectoris (SAP), unstable angina pectoris (USAP) or ...
Modolo Rodrigo R Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas , Campinas, SP , - - 2014
White-coat hypertension (WCH), commonly found in pseudoresistant hypertension, does not pose higher cardiovascular risk than hypertensive status. However, when the decrease of the out-of-office blood pressure does not reach normal levels - the white-coat effect (WCE) - the repercussions are still obscure. We investigated the repercussions of the WCE in ...
Tilz Roland Richard RR Department of Cardiology, Asklepios Klinik St Georg, Lohmuehlenstr 5, 20099 Hamburg, - - 2014
Catheter ablation can abolish clinical ventricular tachycardia (VT) in patients after myocardial infarction (MI). However, VT frequently recurs after ablation. The best ablation strategy is still unknown, particularly in patients with unmappable VTs. We hypothesized that isolation of the arrhythmogenic substrate would be a feasible and effective ablation strategy for ...
Ong Peter P Robert-Bosch-Krankenhaus, Stuttgart, - - 2014
Coronary spasm can cause myocardial ischemia and angina in patients with and those without obstructive coronary artery disease. However, provocation tests using intracoronary acetylcholine administration (ACH-test) are rarely performed in clinical routine in the US and Europe. Thus, we assessed the clinical usefulness, angiographic characteristics and safety of the ACH-test ...
Adlbrecht Christopher C Medical University of Vienna, Department of Internal Medicine II, Division of - - 2014
Ventricular arrhythmias are common after acute myocardial infarction (AMI). Endothelin (ET) is a mediator of microvascular dysfunction and cardiac remodeling with arrhythmogenic potential. The aim of this study was to assess safety and feasibility of selective ET-A receptor blockade in ST-elevation acute coronary syndrome (STE-ACS) within a larger randomized trial. ...
Velders Matthijs A MA Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden; Department of Cardiology, Leiden University Medical Center, Leiden, the - - 2014
Elderly patients constitute a growing part of the population presenting with ST-elevation myocardial infarction (STEMI). The use of primary percutaneous coronary intervention (PCI) in this high-risk population remains poorly investigated. Using the Swedish Coronary Angiography and Angioplasty Registry (SCAAR), we identified consecutive patients with STEMI 80 years or older undergoing ...
Tanındı Aslı A Department of Cardiology, Faculty of Medicine Ufuk University, Ankara-Turkey. - - 2014
Epicardial adipose tissue (EAT) is associated with the presence, severity and extent of atherosclerotic coronary artery disease (CAD) in addition to subclinical atherosclerosis. We investigated if EAT thickness is related to acute myocardial infarction in patients with CAD. We also searched for the association between EAT thickness and objective coronary ...
Kosiuk Jedrzej J Department of Electrophysiology, Heart Center, Leipzig, Strümpellstr. 39, 04289 Leipzig, - - 2014
Recurrence of atrial fibrillation (AF) is frequently observed after AF catheter ablation. However, the predictive value of echocardiographic parameters associated with left ventricular diastolic dysfunction (LVDD) has not been well studied.METHODS AND RESULTS: In 124 consecutive patients (mean age 61 ± 10 years, 60% male) with paroxysmal (n = 70) ...
Bilchick Kenneth C KC Department of Medicine, Cardiovascular Division, University of Virginia Health System, Charlottesville, VA. Electronic address: - - 2014
Using cardiac magnetic resonance (CMR), we sought to evaluate the relative influences of mechanical, electrical, and scar properties at the left ventricular (LV) lead position (LVLP) on CRT response and clinical events. CMR cine displacement encoding with stimulated echoes (DENSE) provides high quality strain for overall dyssynchrony (circumferential uniformity ratio ...
Kraaier Karin K Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER, Enschede, The Netherlands, - - 2014
Microvolt T-wave alternans (MTWA) is an electrocardiographic marker for predicting sudden cardiac death. In this study, we aimed to study the relation between MTWA and scar assessed with cardiac magnetic resonance imaging (CMR) in patients with ischemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM). Sixty-eight patients with positive or negative MTWA ...
Brener Sorin J SJ New York Methodist Hospital, Brooklyn, NY, - - 2014
Aims: To determine the relation between thrombus aspiration (TA) and/or intra-lesion (IL) abciximab with pre-stent Thrombolysis In Myocardial Infarction (TIMI) flow grade and infarct size (IS) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Methods and results: The INFUSE-AMI trial randomised 452 patients with anterior ...
Tousek Petr P Cardiocenter, Charles University Prague, Third Faculty of Medicine, Prague, Czech - - 2014
The incidence and treatment strategies of acute coronary syndrome (ACS) vary by region. Additionally, the clinical spectrum of ACS is changing and outcomes are improving. We assessed the incidence, treatment strategies, and outcomes of ACS for a well-defined population within a well-established network of percutaneous coronary intervention (PCI) centers and ...
de Groote Pascal P 1Service de Cardiologie, Pôle Cardio-Vasculaire et Pulmonaire, Centre Hospitalier Régional et Universitaire de Lille, Lille, France; Inserm U744, Institut Pasteur de Lille, Université de Lille 2, Lille, - - 2014
-Some patients with left ventricular systolic dysfunction (LVSD) have a dramatic improvement in left ventricular ejection fraction (LVEF) after beta-blockade. No study has analyzed the long term echocardiographic and clinical follow-up of this subgroup of patients. -We included in this analysis 174 consecutive patients with LVSD who had a LVEF ...
Niu J M JM Department of Cardiology, Laiwu People's Hospital, Laiwu, Shandong, - - 2014
B-type natriuretic peptide (BNP) is widely used in the treatment of early-stage heart failure and coronary heart disease. In this study, the association of plasma BNP concentration with myocardial infarct (MI) size in patients with acute myocardial infarction (AMI) was investigated. Eighty patients with AMI were enrolled in the MI ...
Carrick David D BHF Glasgow Cardiovascular Research Center, Institute of Cardiovascular and Medical Sciences, University of Glasgow, New York City; West of Scotland Heart and Lung Center, Golden Jubilee National Hospital, New York - - 2014
To assess whether deferred stenting might reduce no-reflow and salvage myocardium in primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). No-reflow is associated with adverse outcomes in STEMI. A prospective single center randomized controlled proof-of-concept trial in reperfused STEMI patients with ≥ 1 risk factors for no-reflow. Randomization ...
Utriainen Karri T KT Turku University Hospital, - - 2014
Obstructive sleep apnoea (OSA) is associated with atherosclerosis and cardiovascular events. Peripheral arterial disease (PAD) represents severe atherosclerosis with a high mortality after vascular surgery. The role of OSA in the prognosis of these patients is not yet established.84 patients (aged 67±9 years) scheduled for sub-inguinal surgical revascularisation were enrolled ...
Teng Zhongzhao Z 1Department of Radiology; Department of Engineering, University of Cambridge, United - - 2014
-Atherosclerotic plaques underlying most myocardial infarctions have thin fibrous caps and large necrotic cores; however these features alone do not reliably identify plaques that rupture. Rupture occurs when plaque structural stress (PSS) exceeds mechanical strength. We examined whether PSS could be calculated in vivo based on virtual histology intravascular ultrasound ...
Zhang Yao-Jun YJ Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Erasmus Medical Center, Rotterdam, The - - 2014
Everolimus-eluting stent (EES) are considered to have better clinical outcomes than other rapamycin derivative-eluting stents; however, the individual trials may not have sufficient power to prove it. This meta-analysis aimed to compare clinical outcomes of EES against other rapamycin derivative-eluting stents. We searched Medline, the Cochrane Library, and other internet ...
Kishimoto Ichiro I Department of Endocrinology and Metabolism, National Cerebral and Cardiovascular Center, Osaka, Japan. Electronic address: - - 2014
Diabetes is a major risk factor for heart failure (HF). We examined whether baseline HbA1c level predicts HF incidence independent of other HF risk factors, including baseline cardiac structural and functional abnormalities. In patients with type 2 diabetes, multivariable Cox regression models were constructed to examine the independent association between ...
Bligaard Niels - - 2014
Abstract Objective. Millions of patients were treated with the sirolimus-eluting Cypher™ and the paclitaxel-eluting Taxus™ coronary stents with potential late occurring increase in event rates. Therefore, the long-term outcome follow up is of major clinical interest. Design. In total, 2.098 unselected patients with ST-segment elevation myocardial infarction (STEMI), non-STEMI, stable ...
Micovic Slobodan S Department of Cardiac Surgery, Dedinje Cardiovascular Institute, University School of Medicine, Belgrade, - - 2014
Concomitant carotid and cardiac surgery carries an increased perioperative morbidity and mortality risk. Whether the hybrid procedure of carotid artery stenting (CAS) and coronary bypass surgery decreases the risk of stroke and other complications is still unknown. The aim of this study was to assess early outcomes after simultaneous hybrid ...
Okin Peter M PM Greenberg Division of Cardiology, Weill Cornell Medical College, New York, New - - 2014
Blacks have a higher prevalence of risk factors for atrial fibrillation (AF), such as hypertension, obesity, and heart failure, than nonblacks. Although population-based studies have demonstrated a lower prevalence and incidence of AF in blacks, the relationship of incident AF to race among hypertensive patients undergoing blood pressure lowering has ...
Pauriah Maheshwar M Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, , Dundee, - - 2014
To determine all-cause mortality in patients with a first myocardial infarct who were treated with simvastatin compared with high-potency statin and simvastatin/ezetimibe combination. Despite statin use, residual cardiovascular risk remains. Therapeutic options include more potent statins or addition of ezetimibe. There is no clinical outcome data on the use of ...
Raja Shahzad G SG From the Departments of *Cardiac Surgery, and †Quality and Safety, Harefield Hospital, London, - - 2014
Despite increasing recognition of the benefits of off-pump coronary artery bypass grafting (CABG), concerns persist regarding its impact on long-term mortality and freedom from reintervention. In this study, we assessed the impact of off-pump CABG on long-term outcomes. From January 2002 to December 2002, a total of 307 consecutive patients ...
Zhang Jiayin J From the Departments of Radiology (J.Z., Y.L., M.L.) and Cardiology (J.P., Z.L.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Rd, Shanghai 200233, - - 2014
Purpose To assess the correlation between the filling pattern of distal coronary vessels in patients with chronic total occlusion (CTO) observed at coronary computed tomographic (CT) angiography and the extent of downstream myocardial infarction (MI). Materials and Methods All patients gave written informed consent, and the institutional review board approved ...
Vujcic I I Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Visegradska 26a, 11000, Belgrade, Serbia, - - 2014
Living alone has been associated with higher risk of acute coronary syndrome in general population, but there are no consistent findings about its effect on prognosis after acute myocardial infarction (AMI). To analyse the relationships between living alone and other risk factors at baseline and long-term survival after AMI. One ...
Lee Park Kay K Center for Outcomes Research, University of Massachusetts Medical School, Worcester, - - 2014
Current guidelines recommend early oral beta-blocker administration in the management of acute coronary syndromes for patients who are not at high risk of complications. Data from patients enrolled between 2000 and 2007 in the Global Registry of Acute Coronary Events (GRACE) were used to evaluate hospital outcomes in three cohorts ...
Tideman Philip A PA Country Health, Adelaide, SA, Australia. - - 2014
To evaluate the impact of the regionalised Integrated Cardiovascular Clinical Network (ICCNet) on 30-day mortality among patients with myocardial infarction (MI) in an Australian rural setting. An integrated cardiac support network incorporating standardised risk stratification, point-of-care troponin testing and cardiologist-supported decision making was progressively implemented in non-metropolitan areas of South ...
Osadchii Oleg E OE Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3, 2200, Copenhagen N, Denmark; Department of Health Science and Technology, University of Aalborg, Fredrik Bajers Vej 7E, 9220, Aalborg, - - 2014
Activation-repolarization coupling refers to the inverse relationship between action potential duration and activation time in myocardial regions along the path of ventricular excitation. This study examined if activation-repolarization coupling plays a role in coordinating repolarization times between the right ventricular (RV) and left ventricular (LV) chambers, and if impaired coordination ...
Wang Ricardo R Hospital Vera Cruz, Belo HorizonteMG, Brasil, Hospital Vera Cruz, Belo Horizonte, MG - - - 2014
Background: The recommendations in guidelines are based on evidence; however, there is a gap between recommendations and clinical practice. Objective: To describe the practice of prescribing evidence-based treatments for patients with acute coronary syndrome in Brazil. Methods: This study carried out a subanalysis of the ACCEPT registry, assessing epidemiological data ...
Ozcan Fırat F Cardiology Clinic, Türkiye Yüksek Ihtisas Training and Research Hospital, Ankara, - - 2014
Fragmented QRS complex (fQRS) is associated with cardiovascular outcomes in various patient populations. Although there were clinical studies investigating the association of fQRS with arrhythmic events in patients with systolic heart failure, the results were conflicting regarding the association of implantable cardioverter defibrillator (ICD) shocks and fQRS. In this study, ...
Maury Philippe P Department of Cardiology, University Hospital Rangueil, 31059 Toulouse Cedex 09, - - 2014
Patients with well-tolerated sustained monomorphic ventricular tachycardia (SMVT) and left ventricular ejection fraction (LVEF) over 30% may benefit from a primary strategy of VT ablation without immediate need for a 'back-up' implantable cardioverter-defibrillator (ICD). One hundred and sixty-six patients with structural heart disease (SHD), LVEF over 30%, and well-tolerated SMVT ...
Mahajan Deepa D Boston Scientific, St. Paul, - - 2014
Adjudication of thousands of implantable cardioverter defibrillator (ICD)-treated arrhythmia episodes is labor intensive and, as a result, is most often left undone. The objective of this study was to evaluate an automatic classification algorithm for adjudication of ICD-treated arrhythmia episodes. The algorithm uses a machine learning algorithm and was developed ...
Schulz Antonia A Charité Universitätsmedizin Berlin, Berlin, - - 2014
This observational study investigated the value of drug-coated balloons (DCB) only strategy in bifurcation lesions in a consecutive series of all comer percutaneous coronary intervention. Local application of paclitaxcel by DCB has clinical benefits in various settings including coronary bifurcations. While so far most bifurcation studies investigated sequential application of ...
Arık Osman Ziya OZ Gümüşhane State Hospital. - - 2014
Optimization of atrioventricular (AV) delay time has positive effects on left ventricular functions in patients with DDD pacemaker. However, the method used for optimization is still debated. In our study, we aimed to evaluate the effect of different AV delay times on variation of left ventricular systolic performance by using ...
Mitro Peter P P.J.Safarik University , Kosice , Slovakia. - - 2014
Overall response rate to cardiac resynchronisation therapy (CRT) is still not optimal. The aim of the study was to evaluate the influence of the regional myocardial contractile reserve during dobutamine infusion in the area of left ventricular (LV) electrode on the response rate and reverse remodelation of left ventricle in ...
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