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Shen Lan L Duke Clinical Research Institute, Durham, NC; Shanghai Renji Hospital, Department of Cardiology, Shanghai, - - 2014
Prior myocardial infarction (MI) is a known risk factor for long-term mortality among acute MI patients; but its prevalence and implications for the short-term outcomes of patients with a new, acute MI remain uncertain. We studied a total of 319,152 consecutively enrolled ST-segment elevation MI (STEMI) and non-STEMI (NSTEMI) patients ...
Taoka T T From the Department of Radiology (T.T., M.S., T.M., T.A., T.O., S.H., K.K.) and Critical Care Medicine (M.F.), Nara Medical University, Nara, Japan; Siemens Japan KK (M.U.), Tokyo Japan; and Siemens Medical Solutions USA (J.X.), New York, New - - 2014
Diffusion kurtosis is a statistical measure for quantifying the deviation of the water diffusion profile from a Gaussian distribution. The current study evaluated the time course of diffusion kurtosis in patients with cerebral infarctions, including perforator, white matter, cortical, and watershed infarctions. Subjects were 31 patients, representing 52 observations of ...
Adlbrecht C - - 2014
Endothelin (ET)-1 is a pro-fibrotic vasoconstrictive peptide causing microvascular dysfunction and cardiac remodelling after acute ST-elevation myocardial infarction (STEMI). It acts via two distinct receptors, ET-A and ET-B, and is involved in inflammation and atherogenesis. Patients with posterior-wall STEMI were randomly assigned to intravenous BQ-123 at 400 nmol/minute (min) or ...
Gür Mustafa M Adana Numune Training and Research Hospital, Department of Cardiology, Adana, Turkey. Electronic address: - - 2014
Reperfusion and ischemic injuries are pathogenetic mechanisms of no-reflow. Oxidative stress plays a critical role during ischemia as well as during the reperfusion phase following ST elevation myocardial infarction (STEMI). We sought to investigate the relationship between no-reflow with paraoxonase-1 (PON-1) activity and oxidative stress markers (total antioxidant capacity (TAC), ...
Roswell Robert O RO Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New - - 2014
The 2013 American College of Cardiology Foundation/American Heart Association ST-segment elevation myocardial infarction (STEMI) guidelines have shifted focus from door-to-balloon (D2B) time to the time from first medical contact to device activation (contact-to-device time [C2D] ). This study investigates the impact of prehospital wireless electrocardiogram transmission (PHT) on reperfusion times to ...
Frommeyer Gerrit G Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, - - 2014
The most recent European Society of Cardiology (ESC) update on atrial fibrillation has introduced vernakalant (VER) for pharmacological cardioversion of atrial fibrillation. The aim of the present study was to investigate the safety profile of VER in a sensitive model of proarrhythmia.METHODS AND RESULTS: In 36 Langendorff-perfused rabbit hearts, VER ...
Rivera Santiago S Division of Cardiology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, - - 2014
Pseudo ischemic ST segment changes during supraventricular tachycardia (SVT) are not yet fully understood. Our aim was to determine whether venticulo-atrial (VA) conduction during SVT may be a possible mechanism for ST depression (STd) in SVT. Patients undergoing SVT ablation (2010-2012) were analyzed (n = 72).Typical atrioventricular node reentrant tachycardia ...
De Abreu Maximiliano M Grupo de Estudio, Docencia e Investigación Clínica, Investigadores del Registro Epi-Cardio, Buenos Aires, Argentina. Electronic address: - - 2014
Observational studies have reported a marked discrepancy between the risk estimated by scores and the use of an invasive strategy in patients with acute coronary syndromes. The objective is to describe the criteria used to decide an early invasive strategy and to determine the differences between those criteria and the ...
Muzaffar Tasneem T Department of Cardiovascular and Thoracic Surgery, Soura, Kashmir, - - 2014
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly which represents one of the most common causes of myocardial ischemia and infarction in children. This anomaly, if left untreated, results in a very high mortality rate within the first year of life. ...
Velders M A MA Department of Cardiology, Medical Center Leeuwarden, PO Box 888, 8901 BR, Leeuwarden, the Netherlands, - - 2014
Everolimus-eluting stents (EES) were superior to sirolimus-eluting stents (SES) in a dedicated myocardial infarction trial, a finding that was not observed in trials with low percentages of ST-elevation myocardial infarction (STEMI). Therefore, this study sought to investigate the influence of clinical presentation on outcome after EES and SES implantation. A ...
Maskhulia L L Clinical Centra of Sports Medicine and Rehabilitation of Tbilisi State Medical University, Tbilisi, - - 2014
Athlete's heart should be differentiated from the hypertrophic cardiomyopathy (HCM)-leading cause of exercise related sudden cardiac death in young athletes. Some genetic variations of HCM are characterized by a benign clinical course and a delayed onset of the disease. Therefore, substantial increase of left ventricular wall thickness (LVWT) in adolescent ...
Hughes William S WS Medicine, Georgetown University, 3800 Resevoir Road NW, Washington, District of Columbia, 20037, - - 2014
Studies of autopsies of military members dying in three US wars indicate that the prevalence of atherosclerosis in successive cohorts of healthy young men and women has dramatically decreased over the past half century. The objective of this study was to compare the decline in the prevalence of atherosclerosis and ...
Arso Irsad A IA Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta, - - 2014
Aim: to compare the in-hospital major cardiovascular events between thrombolysis therapy and primary percutaneous coronary intervention (PCI) in patients with ST-elevation acute myocardial infarction (STEMI. Methods: the study design is retrospective cohort. Medical record of patients with STEMI onset <12 hour receiving thrombolysis treatment or primary PCI in Dr. Sardjito ...
Lee Ki Hong KH 0000-0002-9938-3464 Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, - - 2014
We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n=270, 92.3±2.3 yr old) with octogenarian AMI patients (n=2,145, 83.5±2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, ...
Kim Jeong Hun JH 0000-0002-5637-1121 The Heart Center of Chonnam National University Hospital, Gwangju, Korea. ; Department of Public Health, Chonnam National University Medical School, Gwangju, - - 2014
The aim of this study was to evaluate whether the clinical outcomes were associated with socioeconomic status (SES) in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI). The author analyzed 2,358 patients (64.9 ± 12.3 yr old, 71.5% male) hospitalized with AMI between November 2005 and ...
Romano Edson Renato ER Unidade de Terapia Intensiva, Hospital do Coração, São Paulo, SP, - - 2014
Background: Available predictive models for acute coronary syndromes (ACS) have limitations as they have been elaborated some years ago or limitations with applicability. Objectives: To develop scores for predicting adverse events in 30 days and 6 months in ST-segment elevation and non-ST-segment elevation ACS patients admitted to private tertiary hospital. ...
Shimizu Atsuya A Department of Cardiology, National Center for Geriatrics and Gerontology, Obu, Japan; Department of Cardiology, Nagoya University, Nagoya, - - 2014
Cerebral white matter lesions (WML) are known to increase with age, as is left ventricular (LV) diastolic dysfunction with normal contraction. Although aging is a common risk factor, the link between these diseases is not fully understood. The aim was to clarify this relationship, using the ratio between early diastolic ...
Shacham Yacov Y Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: - - 2014
Previous data reported worse outcomes in female patients after acute ST elevation myocardial infarction (STEMI), related at least in part to less aggressive and nonparallel treatment. We investigated the presence of gender differences in left ventricular (LV) systolic and diastolic function in patients presenting with first STEMI, treated with primary ...
Borde Laura L Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Boulevard de Colonster 20, B41, 4000, Liège, - - 2014
To assess the prognostic value of echocardiographic parameters of left ventricular (LV) function in horses with systemic inflammatory response syndrome (SIRS). Prospective observational study. Veterinary teaching hospital. Forty-one horses admitted for colic with clinical evidence of SIRS. All horses underwent Doppler echocardiographic examination on admission. LV echocardiographic parameters, including pulsed-wave ...
Vural Murat M Department of Radiology, Ankara Numune Education and Research Hospital, Talatpasa Bulvarı, Sıhhiye, Ankara, Turkey, - - 2014
The aim of the present study was to evaluate the relationship between epicardial fat tissue (EFT) volume and left ventricular diastolic function. A total of 63 patients (29 male, 34 female, mean age 57.8 ± 10.9 years) were enrolled in the study. Multidetector computed tomography (MDCT) and 2D transthoracic echocardiography were performed in ...
Matoshvili Z Z Central University Clinic after N. Kipshidze, Tbilisi; Tbilisi State Medical University, Department of Internal Medicine №1, - - 2014
Early repolarization pattern is a common ECG pattern characterized by J-point and ST segment elevation in 2 or more contiguous leads. There are some opinions that early repolarization may be associated with some kind of arrhythmias (including life-threatening arrhythmias) Aim of this study was to declare correlation between early repolarization ...
Youn Jong-Chan JC 0000-0003-0998-503X Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, - - 2014
Heart failure (HF) complicating acute myocardial infarction (AMI) is common and is associated with poor clinical outcome. Limited data exist regarding the incidence and in-hospital mortality of AMI with HF (AMI-HF). We retrospectively analyzed 1,427 consecutive patients with AMI in the five major university hospitals in Korea at two time ...
Zhang Qi Q Department of Cardiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Sirolimus-eluting stents (SES) with a biodegradable polymer coating have demonstrated promising results but have not been compared to SES with a durable polymer in high-risk patients. We compared the efficacy of these 2 stent types in patients with acute myocardial infarction (STEMI). One thousand one hundred ninety-two STEMI patients were ...
Choi Woong Gil WG Division of Cardiology, Department of Internal Medicine, Konkuk University College of Medicine, Chungju, - - 2014
Functional mitral regurgitation (FMR) and myocardial dyssynchrony commonly occur in patients with dilated cardiomyopathy (DCM). The aim of this study was to elucidate changes in FMR in relation to those in left ventricular (LV) dyssynchrony as well as geometric parameters of the mitral valve (MV) in DCM patients during dobutamine ...
Mohammed Selma F SF Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Mayo Graduate School, Mayo Clinic, Rochester, - - 2014
This study sought to determine the frequency of left ventricular amyloid in heart failure with preserved ejection fraction (HFpEF). Left ventricular amyloid deposition can cause diastolic dysfunction and HFpEF. Autopsy of left ventricular specimens from patients with antemortem diagnosis of HFpEF without clinically apparent amyloid (n = 109) and from control ...
Alqarawi Wael A WA Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, Toronto, Canada; University of Toronto, Toronto, - - 2014
Although the adverse prognosis of Q-waves on electrocardiogram (ECG) has been demonstrated, the prognostic significance of prominent R wave (PRW) in V1 or V2 across a broad spectrum of acute coronary syndrome (ACS) has not been specifically studied. In the Global Registry of Acute Coronary Events (GRACE) and the Canadian ...
Sarıkaya Savaş S Department of Cardiology, Bozok University and Cumhuriyet University Faculty of Medicine, Yozgat, Turkey. - - 2014
Objectives: Our aim was to determine whether there is a relationship between admission gamma-glutamyltransferase (GGT) and subsequent heart failure hospitalizations in patients with acute coronary syndrome. Study design: We selected 123 patients with newly diagnosed acute coronary syndrome of ejection fraction (EF) <45%. Patients were followed 15±10 months, and the ...
Liu Yongxing - - 2014
Coronary artery perforation (CAP) is a rare, serious complication of percutaneous coronary intervention (PCI). Many studies have addressed the incidence, risk factors, and management of CAP in different countries except China. The aim of this study is to determine the risk factors and types of treatment for coronary perforation occurring ...
Conrotto Federico F Department of Cardiology, Città della Salute e della Scienza Hospital, Turin, Italy. Electronic address: - - 2014
Percutaneous coronary intervention (PCI) with drug-eluting stents is an accepted alternative to surgery for the treatment of unprotected left main coronary artery (ULMCA) disease, but the long-term outcome in elderly patients is unclear. Aim of our study was to compare the clinical outcomes of octogenarians with ULMCA disease treated either ...
Devereaux P J PJ The authors' affiliations are listed in the - - 2014
Marked activation of the sympathetic nervous system occurs during and after noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and death without inducing hemodynamic instability. We performed a blinded, randomized trial with a 2-by-2 factorial design to allow separate evaluation of low-dose clonidine versus ...
Shimokawahara Hiroto H Institute for Clinical Research and Division of Cardiology, National Hospital Organization Kagoshima Medical Center, Kagoshima, - - 2014
Although vascular endothelial growth factor (VEGF) is elevated in patients with acute myocardial infarction (AMI), the clinical significance of its elevation remains unclear. The present study was designed to determine the relationship between VEGF and left ventricular dimension in patients with AMI. Plasma VEGF levels were examined by enzyme-linked immunosorbent ...
Li Min M Healthy Heart Program Prevention Clinic, St. Paul's Hospital, Vancouver, BC, - - 2014
We describe a patient with markedly elevated lipoprotein(a) (Lp(a)) without any other lipid abnormalities. After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much better response than usually reported.
Ter Haar C Cato CC Cardiology Department, Leiden University Medical Center, Leiden, The - - 2014
The ECG is important in diagnosis and triage in the initial phase of the acute coronary syndrome (ACS). The primary goal of making an ECG at first medical contact should be the reliable detection of cardiac ischemia, thus facilitating a correct triage by corroborating the diagnosis of ACS. Ischemia detection ...
Ricci Renato Pietro RP Department of Cardiology, San Filippo Neri Hospital, , Rome, - - 2014
Inappropriate implantable cardioverter defibrillators (ICD) therapies have been associated with multiple adverse effects, including worse quality of life and prognosis. We evaluated the possibility of predicting atrial fibrillation (AF)-related inappropriate ICD shocks through continuous monitoring of device diagnostics. 1404 ICD patients were prospectively followed in an observational research by 74 ...
Demidova Marina M MM Department of Cardiology, Lund University, Lund, Sweden; Federal Centre of Heart, Blood and Endocrinology, St. Petersburg, Russia. Electronic address: - - 2014
Certain types of the early repolarization (ER) phenomenon, previously considered to be benign, have been reported to be associated with ventricular fibrillation (VF), both in population-based studies and in the myocardial infarction (MI) settings. Our aim was to analyse whether QRS widening and appearance of J-wave-pattern in experimental MI settings ...
Kali Avinash A 1Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA; Department of Bioengineering, University of California, Los Angeles, CA; Department of Radiology, Northwestern University, Chicago, - - 2014
-LGE CMR is a powerful method for characterizing MI, but the requisite gadolinium infusion is estimated to be contraindicated in nearly 20% of MI patients due to end-stage chronic kidney disease. The purpose of this study is to investigate whether T1 Cardiovascular-Magnetic-Resonance Imaging (CMR) obtained without contrast agents at 3T ...
Ayça Burak B Bağcılar Education and Research Hospital. - - 2014
Syntax score (SxS) is demonstrated to predict long-term outcomes in stable patients with coronary artery disease. But, its prognostic value for patients with acute coronary syndrome remains unknown. Therefore, in this study we aimed to evaluate whether SxS could predict in-hospital outcomes for patients admitted with ST elevation myocardial infarction ...
Demyanets Svitlana S Department of Internal Medicine II, Medical University of Vienna, Währinger-Gürtel 18-20, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, Währinger-Gürtel 18-20, 1090 Vienna, Austria. Electronic address: - - 2014
The study aim was to determine the predictive value of interleukin (IL)-33, a recently described member of the IL-1 family of cytokines, for the development of in-stent restenosis (ISR). IL-33 serum levels were measured in 387 consecutive patients undergoing percutaneous coronary intervention (PCI) of whom 193 had stable angina, 93 ...
Inagawa Tetsuji T Department of Neurosurgery, Shimane Prefectural Central - - 2014
We studied the risk factors associated with cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH). The subjects were 370 patients with ruptured aneurysms who fulfilled all of the following criteria: admission by day 2 after onset, operation performed by day 3 by the same surgeon (T.I.), Hunt-Hess grade I-IV, availability of ...
Chen Ming-Ren MR Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Junior College of Medicine Nursing and Management, Taipei, Taiwan; Mackay Medical College, Taipei, - - 2014
Myocardial iron overload leading to congestive heart failure (HF) or arrhythmias is a recognized complication in thalassemia patients undergoing chronic blood transfusion. The relationship between myocardial iron load, subclinical systolic dysfunction, and clinical events remains less well known. We studied a total of 77 subjects, comprising 37 thalassemia patients (mean ...
Mamas Mamas A MA Manchester Heart Centre, Manchester Royal Infirmary, Oxford Road, Manchester, United Kingdom; Institute of Cardiovascular Sciences, University of Manchester, Oxford Road, Manchester, United Kingdom. Electronic address: - - 2014
Cardiogenic shock (CS) remains the leading cause of mortality in patients hospitalized with acute myocardial infarction (AMI). The transradial access site (TRA) has become increasingly adopted as a default access site for percutaneous coronary intervention (PCI); however, even in experienced centers that favor the radial artery as the primary access ...
Boles Usama - - 2014
Abstract Objective: To assess the relationship between hematological inflammatory signs, cardiovascular risk (CV) factors and prognosis in patients presenting with acute myocardial infarction (AMI) and coronary artery ectasia (CAE). Design: We investigated 3321 AMI patients who required urgent primary percutaneous intervention, in two centres in the United Kingdom between January ...
Zanon Francesco F 1Arrhythmia & EP Unit, Cardiology Department, Santa Maria Della Misericordia Hospital, Rovigo, - - 2014
-One of the reasons for patient non-response to cardiac resynchronization therapy (CRT) is a suboptimal left ventricular (LV) pacing site. LV electrical delay (Q-LV interval) has been indicated as a prognostic parameter of CRT response. This study evaluates the LV delay for optimization of the LV pacing site. -Thirty-two consecutive ...
Patel Akshay J AJ Department of Cardiac Surgery, St. George's Hospital, London, - - 2014
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, 'What is the optimal revascularization technique for isolated disease of the left anterior descending artery (LAD) in terms of patient survival, morbidity such as myocardial infarction (MI) and need for repeat target ...
Yingchoncharoen Teerapat T Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
Increased left ventricular (LV) dimensions are an indication for surgery in patients with asymptomatic mitral regurgitation, but M-mode or two-dimensional measurements have known limitations. The aim of this study was to determine the value of three-dimensional echocardiography in predicting postoperative outcomes after mitral surgery. Sixty-seven patients with severe asymptomatic or ...
Tigen Kursat K Department of Cardiology, Marmara University Faculty of Medicine, Istanbul, - - 2014
Severe mitral stenosis (MS) may impair left atrial (LA) pump function, and increase LA and pulmonary venous pressure resulting in right ventricular (RV) systolic dysfunction. The aim of this study was to evaluate biventricular and LA function after percutaneous mitral balloon valvuloplasty (PMBV) by tissue Doppler (TDI) and speckle tracking echocardiography ...
Calvert Patrick A PA University Hospitals Birmingham NHS Foundation Trust, Birmingham; University of Cambridge, Cambridge; Papworth Hospital NHS Foundation Trust, Cambridge, United - - 2014
Post-infarction ventricular septal defect (PIVSD) carries a grim prognosis. Surgical repair offers reasonable outcomes in patients who survive a healing phase. Percutaneous device implantation represents a potentially attractive early alternative. PIVSD closure was attempted in 53 patients from 11 centers (1997-2012) (age 72±11 years; 42% female). 19% had previous surgical ...
Cortigiani Lauro L Cardiology Division, Campo di Marte Hospital, Lucca, - - 2014
The prognostic value of Doppler-derived coronary flow velocity reserve (CFVR) of the left anterior descending coronary artery in patients with type 2 diabetes with preserved left ventricular systolic function and without flow-limiting stenoses on angiography remains undetermined. The study sample consisted of 144 patients with type 2 diabetes (82 men; ...
Zimmermann-Viehoff F F Department of Psychiatry and Psychotherapy, Charité University Medical School Berlin, Campus Benjamin Franklin, Berlin, - - 2014
Antidepressants reduce depressive symptoms in patients with coronary heart disease, but they may be associated with increased mortality. This study aimed to examine whether the use of tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRI) is associated with mortality in patients with coronary heart disease, and to determine whether ...
Ybarra Juan J aOverweight and Obesity Unit bDr Ballesta's Laparoscopic Surgical Center, Centro Médico Teknon, Barcelona, Spain cCleveland Clinic Foundation, Medina Hospital, Medina, Ohio, - - 2014
Alanine aminotransferase (ALT) is a marker of nonalcoholic fatty liver disease (NAFLD) and predicts type 2 diabetes mellitus (DM2) as well as coronary events independently of traditional risk factors and the features of the metabolic syndrome. The extent to which interventricular septum thickness (IVS) and left ventricular mass (LVM) are ...
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