Search Results
Results 251 - 300 of 1689
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Song Ze-Zhou - - 2011
A 26-year-old man admitted with dysphasia and bilateral headache for three days. He had no known risk factors for stroke. Transthoracic two-dimensional echocardiography showed prominent trabeculations, with deep intertrabecular recesses in apex of the right ventricle. The multi-detector-row spiral cerebral computerized tomography revealed a little infarction in bilateral temporal and ...
Sato Shinsuke - - 2009
We encountered a case of head trauma with very unusual delayed events. A 68-year-old woman was admitted to our hospital after receiving a direct impact to her occiput in a traffic accident. Head CT scans showed a thin acute epidural hematoma in the posterior fossa corresponding to a linear fracture, ...
Benejam Bessy - - 2009
Malignant middle cerebral artery (MMCA) infarction is associated with a mortality rate of 80% under conservative treatment. Decompressive hemicraniectomy (DH) reduces mortality and improves the functional outcome of surviving patients. The purpose of this study was to examine quality of life (QoL) and neurobehavioral deficits in patients with space-occupying infarctions ...
Ralea I-C - - 2009
BACKGROUND AND PURPOSE: Although brain embolism is a uncommon complication of myocardial infarction, sequential treatment of cerebral and coronary artery occlusion within a 4-hour time window is unusual. SUMMARY: of case A 60 year-old man experienced successful intravenous recombinant thrombolysis (tPA) for acute middle cerebral artery (MCA) occlusion followed by ...
Kim Hyun-Ah - - 2009
OBJECTIVES: To document otolith dysfunction in patients with posterior inferior cerebellar artery (PICA) territory cerebellar infarction. METHODS: From March to October 2006, 14 consecutive patients with PICA territory cerebellar infarctions (brainstem spared) diagnosed by brain MRI from the acute stroke registry at the Keimyung University Dongsan Medical Center were enrolled ...
Liem M K - - 2009
BACKGROUND: Cognitive decline is one of the clinical hallmarks of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a cerebrovascular disease caused by NOTCH3 mutations. In this 7-year follow-up study, we aimed to determine whether there are associations between the different radiologic hallmarks in CADASIL and decline in ...
Kim Ji Soo - - 2009
OBJECTIVES: This paper aims to determine the frequency of isolated labyrinthine infarction as an initial manifestation of anterior inferior cerebellar artery (AICA) territory infarction and discuss its clinical implication. METHODS: We studied 54 consecutive patients with AICA infarction diagnosed by brain MRI from the acute stroke registry. RESULTS: We identified ...
Ohta Yasuyuki - - 2009
OBJECTIVE: Free radicals are important in causing neural cell injury during cerebral infarction. Although there was a randomized, placebo-controlled, double-blind study at multiple centers in Japan showing the efficacy of the free radical scavenger, edaravone, in acute cerebral infarction, to date the clinical studies are few. This study investigated the ...
Mori Shuji - - 2009
Ischemic brain infarction is high among th causes of death in Japan, and the medical and social burden by severe sequela is also extremely serious. In this symposium, we show that treatment with anti-high mobility group box 1 (HMGB1) monoclonal antibody (mAb) remarkably ameliorated brain infarction induced by 2-hour occlusion ...
Maher Kevin O - - 2009
OBJECTIVE: Report on the use of near infrared spectroscopy (NIRS) for the recognition of pericardial tamponade after neonatal congenital heart surgery. DESIGN: Case report. SETTING: Pediatric cardiac intensive care unit. PATIENT: Seven-day-old term infant with double inlet left ventricle, hypoplastic aortic arch, and ascending aorta, postoperative day (POD) 3 from ...
Park Jaechan - - 2009
Decompressive craniectomy procedures are used for malignant hemispheric infarctions. However, the temporal muscle and fascia are significant limiting factors for external herniation of an edematous brain. Therefore, the authors performed a decompressive craniectomy and expansive duraplasty combined with resection of the temporal muscle and fascia for 15 patients with a ...
Naess Halvor - - 2009
BACKGROUND: We hypothesized that patients with cerebral infarction on preadmission warfarin have less severe neurological deficits on admittance, less severe neurological deficits 1 week after the onset of cerebral infarction and a larger improvement as to neurological deficits within 1 week of acute cerebral infarction. METHODS: All patients with cerebral ...
Rehni Ashish K - - 2009
The present study was designed to pharmacologically investigate the possible role of nuclear factor kappa B (NF-kappaB) in the reversal of global cerebral injury induced by ischemia and reperfusion after ischemic postconditioning. Bilateral carotid artery occlusion for 17 min followed by reperfusion for 24 h was employed to produce ischemia- ...
Lee Eugene - - 2009
BACKGROUND AND PURPOSE: Although cardiac embolism has been shown to be the leading stroke mechanism of posterior cerebral artery (PCA) territory infarction, intrinsic PCA atherosclerotic disease may play a more important role in regions where intracranial diseases are prevalent. We aimed to assess the etiologies and stroke pattern of PCA ...
Nomura Shosaku - - 2009
AIM: Platelet-derived microparticles (PDMPs) play roles in normal hemostatic responses to vascular injury because they possess prothrombinase activity. Although the most widely used method for studying PDMP is flow cytometry, we previously developed an enzyme-linked immunosorbent assay (ELISA) method as an easier and more reproducible PDMP assay. The purpose of ...
Goto Atsuko - - 2009
OBJECTIVE: This study was performed to analyze the locomotion outcome of hemiplegic patients with stroke and to explore the factors influencing it. METHODS: A total of 247 patients (mean age 65.6 +/- 10.5 years) admitted to our hospital for rehabilitation were included in the study. Their cardinal neurologic sign was ...
Kishi Masahiko - - 2009
Isolated hemiataxia after a medullary infarct is rare. We describe a case of isolated hemiataxia after a small infarct localized at the ipsilateral dorsolateral medulla. An 83-year-old man developed acute onset of ataxia in the left arm and in both legs. Speech and extraocular movement were normal, and he did ...
Perez-Nellar Jesus - - 2009
INTRODUCTION: Malignant MCA infarction results in significant space occupying effect and intracranial pressure (ICP) increment. Due to the high mortality rate in such patients, the term malignant MCA infarction was coined. METHODS: We studied a patient who developed a sudden onset of slurred speech, right hemiplegia, and decreased level of ...
Arasaki Keisuke - - 2009
We examined the relationship between the degree to which motor unit number estimates (MUNEs) decrease in association with the clinical features of patients with the infarction. Using a multiple-point stimulation technique, we obtained the MUNE of the hypothenar muscle group in 13 age-matched control subjects and 30 patients with cerebral ...
Ling Li - - 2009
BACKGROUND: The study aimed to prospectively observe the clinical and neuroimaging features of pontine infarction with pure motor hemiparesis (PMH) or hemiplegia at early stage. METHODS: In 118 consecutive selected patients with the first-ever ischemic stroke within 6 hours after onset, fifty of them presented with PMH or hemiplegia and ...
Farooq Muhammad U - - 2009
Malignant cerebral infarction is a life-threatening condition with case fatality rates of approximately 80% in adults with malignant infarction of the middle cerebral artery. No medical treatment has been proven effective for this condition. Decompressive hemicraniectomy within 48 h of massive cerebral infarction significantly reduces mortality and improves outcome in ...
Lin Ke - - 2009
PURPOSE: Conventional noncontrast CT (NCCT) is insensitive to hyperacute cerebral infarction in the first 3 h. Our aim was to determine if CT perfusion (CTP) can improve diagnostic accuracy over NCCT for patients presenting with stroke symptoms in the 3-hour window. METHODS: Consecutive patients presenting to our emergency department with ...
Kim Jin-Seok - - 2009
BACKGROUND: There are conflicting evidences on endothelial function in lacunar infarction. This may be attributed to the effects of risk factors on the vascular smooth muscle. To test endothelial function only in patients with lacunar infarction, we evaluated the endothelium-dependent and -independent vasodilatation of the brachial artery. METHODS: We enrolled ...
Selakovic Vesna V Institute for Medical Research, MMA, Belgrade, - - 2009
The aim of this study was to define concentration changes of soluble adhesion molecules (sICAM-1, sVCAM-1 and sE-Selectin) in cerebrospinal fluid and plasma, as well as, number of peripheral blood leukocytes and the albumin coefficient in the patients with the acute brain infarction. We also, analyzed the correlation between the ...
Lee Hyung - - 2009
Antemortem diagnosis of isolated inner ear infarction remains a diagnostic challenge since current imaging techniques do not permit differentiation of isolated labyrinthine infarction from other more benign disorders involving the inner ear. An 81-year-old woman with diabetes, hypertension and hypercholesterolemia presented with vertigo and hearing loss. Initial examination revealed findings ...
Thibert Ronald L - - 2009
Uncal herniation due to a large cerebral infarct is well-described in adults, with high rates of morbidity and mortality. This phenomenon, however, has not been previously reported in neonates. We present a newborn male delivered via cesarean section with difficult extraction who presented with frequent seizures. He was found to ...
Schmidt J Michael - - 2008
OBJECT: The authors sought to determine frequency, risk factors, and impact on outcome of asymptomatic cerebral infarction due to vasospasm after subarachnoid hemorrhage (SAH). METHODS: The authors prospectively studied 580 patients with SAH admitted to their center between July 1996 and May 2002. Delayed cerebral ischemia (DCI) from vasospasm was ...
Funayama Michitaka - - 2008
BACKGROUND: The relationship between hemispatial neglect and callosal lesions is not fully understood. METHOD: A 74-year-old woman exhibited destruction of the posterior part of the genu and the entire truncus of the corpus callosum and a part of the right cingulate sulcus after infarction of the right pericallosal artery. RESULTS: ...
Margolin Edward - - 2008
We describe a 73-year-old man who developed diplopia as the initial manifestation of a left thalamic infarction. By the time he reached the emergency department, clouded consciousness precluded localization of the lesion. Results of brain MRI were initially interpreted as negative. Ophthalmologic examination several hours later disclosed a small vertical ...
Thöne-Reineke Christa - - 2008
OBJECTIVE: Ceftriaxone has been reported to reduce neuronal damage in amyotrophic lateral sclerosis and in an in-vitro model of neuronal ischaemia through increased expression and activity of the glutamate transporter, GLT1. We tested the effects of ceftriaxone on mortality, neurological outcome, and infarct size in experimental stroke in rats and ...
Mentese A - - 2008
BACKGROUND: An increasing number of studies have shown that ischaemia-modified albumin (IMA) levels rise in a number of acute ischaemic conditions such as cerebral infarct, myocardial infarct, pulmonary infarct and mesenteric infarct, suggesting that IMA may be useful as a diagnostic marker. A study was undertaken to investigate the effect ...
Seidel Günter - - 2009
BACKGROUND AND PURPOSE: We conducted this prospective study to evaluate the time course of hemorrhagic transformation (HT) and arterial recanalization in the early phase of ischemic stroke using transcranial sonography (TCS). METHODS: Fifty-five patients with acute ischemic hemispheric stroke <32 hours after symptom onset were studied. A 2-MHz sector probe ...
Austinat Madeleine - - 2009
BACKGROUND AND PURPOSE: Brain edema is detrimental in ischemic stroke and its treatment options are limited. Kinins are proinflammatory peptides that are released during tissue injury. The effects of kinins are mediated by 2 different receptors (B1 and B2 receptor [B1R and B2R]) and comprise induction of edema formation and ...
Sasaki Toshihiro - - 2009
Suppression of peri-infarct depolarizations (PIDs) is one of the major mechanisms of hypothermic protection against transient focal cerebral ischemia. Previous studies have shown the lack of hypothermic protection against permanent focal ischemia. We hypothesized the lack of hypothermic protection was due to the poor efficacy in suppression of PIDs. To ...
Murkin John M - - 2008
This article will review the pathogenesis of perioperative neurological injury in patients undergoing coronary revascularization. The high percentage of such patients with diabetes or concomitant cerebrovascular disease renders this population particularly susceptible to injury as a consequence of both hypoperfusion and atheroemboli. The role of transesophageal echocardiography for assessment of ...
Huttner Hagen B - - 2008
The space-occupying so-called "malignant" middle cerebral artery infarction is-besides acute basilar artery occlusion-the most devastating form of ischemic stroke. Until recently, there was no proven treatment. In 2007, results from randomized controlled trials provided evidence for the benefit of early hemicraniectomy with respect to mortality after 3 months. This review ...
Solans-Laqué Roser - - 2008
Cerebrovascular accidents (CVAs) and multi-infarct dementia have rarely been reported as presenting symptoms of giant cell arteritis (GCA), although 3%-4% of patients with GCA may present with CVAs during the course of the disease. We describe 7 patients with biopsy-proven GCA who presented with stroke or multi-infarct dementia. Most of ...
Sacco Simona - - 2009
Different types of migraine have been reported in 20-40% of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). We describe a novel migrainous manifestation of CADASIL consisting in status migrainosus and persistent aura without infarction. The symptoms resolved after i.v. treatment with lorazepam and mannitol.
Cho K-H - - 2009
BACKGROUND: Atherosclerotic middle cerebral artery (MCA) disease may produce subcortical infarction either in the upper part (corona radiata, CR) or in the lower area (internal capsule, IC) of the pyramidal tract. The study aimed to see whether the location of MCA stenosis (proximal vs distal) determines the location of subcortical ...
Foster Kelley A - - 2009
Vascular endothelial growth factor (VEGF) may mediate increases in vascular permeability and hence plasma extravasation and edema following cerebral ischemia. To better define the role of VEGF in edema, we examined the effectiveness of a novel small molecule KDR kinase inhibitor Compound-1 in reducing edema and infarct volume following focal ...
Koike Akira - - 2008
BACKGROUND: Recent investigations have demonstrated that cerebral oxyhemoglobin (O(2)Hb) decreases during exercise in patients with left ventricular dysfunction, reflecting a cerebral hypoxia. We sought to establish a prognostic value of decreased cerebral O(2)Hb during exercise in cardiac patients, and to compare it with those of indexes obtained from cardiopulmonary exercise ...
Bandt S Kathleen - - 2008
Benedikt syndrome is a rare but debilitating constellation of symptoms that manifests from infarction of the red nucleus, cerebral peduncle, oculomotor fascicles, and lower oculomotor nucleus. Clinically, it presents as ipsilateral cranial nerve III palsy, contralateral hemiataxia with intention tremor, contralateral hemiparesis, and hyperactive tendon reflexes. Commonly, the tremor upon ...
Math Ravi S - - 2008
A 50-year-old female developed cortical blindness 5 hours after coronary angiography. A non-contrast-enhanced computed tomographic scan of the brain revealed bilateral occipital and middle cerebral/posterior cerebral artery watershed territory infarcts with a possibility of subarachnoid hemorrhage (SAH). Magnetic resonance imaging of the brain revealed the above infarcts, but not SAH. ...
Zhao Honggang H Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198-5850, - - 2008
Intraluminal occlusion of the middle cerebral artery (MCA) is used extensively in cerebral ischemia research. We tested a modified nylon suture in a rat model of middle cerebral artery occlusion (MCAO) under two anesthesia regimens. Sprague-Dawley rats were divided into six groups (Group 1, Poly-L-lysine-coated suture under ketamine/xylazine anesthesia; Group ...
Hashimoto Junichiro - - 2008
Stiffening of large arteries increases pulsatile pressure and flow stresses, which extend to the microcirculation in vasodilated organs such as the brain and kidneys. Subclinical cerebral lacunar infarction and albuminuria, both of which are early manifestations of microvascular damage, have been shown to be potentially interrelated in hypertension and with ...
Lin Ke - - 2009
INTRODUCTION: We aimed to determine if volumetric mismatch between tissue at risk and tissue destined to infarct on computed tomography perfusion (CTP) can be described by the mismatch of Alberta Stroke Program Early CT Score (ASPECTS). MATERIALS AND METHODS: Forty patients with nonlacunar middle cerebral artery infarct <6 h old ...
Sundt Thoralf M TM - - 2008
BACKGROUND: The rapid evolution of endovascular approaches to arch reconstruction such as brachiocephalic debranching and endovascular stent grafting renders an accurate understanding of contemporary outcomes of conventional open arch surgery particularly relevant. METHODS: Cases of arch reconstruction were identified by search of the computerized cardiovascular surgical database. Perioperative (30-day) outcomes ...
Choi Jae-Hwan - - 2008
A 31-year-old woman developed bilateral posterior ischemic optic neuropathy and infarctions of the cerebral arterial border zones and spinal cord after correction of malignant hypertension. Although a few reports have described patients with neurologic abnormalities after treatment of malignant hypertension, full clinical and neuroimaging documentation of this combination of findings ...
Grogan Kelly - - 2008
Brain injury is a major source of patient morbidity after cardiac surgery, and is associated with prolonged hospitalization, excessive operative mortality, high hospital costs, and altered quality of life. Frequency and the clinical manifestations depend on multiple factors, including the completeness and timing of neurologic testing. Ischemic brain infarctions may ...
Springer Priscilla - - 2009
INTRODUCTION: Cerebral infarction is an important cause of neurological sequelae in childhood tuberculous meningitis (TBM). AIM: To investigate neurodevelopmental outcome and development of motor sequelae in TBM-related cerebral infarction. METHODS: A group of 64 children with TBM and computerized tomographic (CT) evidence of infarction were compared with regard to motor ...
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