Search Results
Results 301 - 350 of 856
< 2 3 4 5 6 7 8 9 10 11 12 >
Sibilitz Kirstine L KL Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address: - - 2014
We tested the hypothesis that moderately elevated plasma creatinine levels and decreased levels of estimated glomerular filtration rate (eGFR) are associated with increased risk of myocardial infarction, ischemic heart disease, and early death in the general population. We studied 10,489 individuals with a plasma creatinine measurement and calculated eGFR from ...
Cadrin-Tourigny Julia J Electrophysiology Service, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, - - 2014
Despite amiodarone's established safety profile in the setting of heart failure, it is unknown whether its impact on cardiovascular outcomes in patients with atrial fibrillation is modulated by left ventricular function. A pooled analysis of 3307 patients (age 68.0±0.2 years; 31.1% female) enrolled in AFFIRM and AF-CHF trials was conducted ...
Pu Lijin - - 2014
To investigate the effect of cardiac resynchronization therapy (CRT) with right ventricular sense triggered left ventricular pacing for chronic heart failure (CHF). Thirty patients who were eligible for the Class I indication of CRT were enrolled and the informed consents were signed. Left ventricular ejection fraction (LVEF), diastolic mitral flow ...
Kamiński Rafał - - 2014
Background: Atrial fibrillation (AF) is a common arrhythmia in people in elderly and in many cases is responsible for stroke or pulmonary embolism. One of the factors facilitating atrial thrombus formation is anatomical morphology of atria, especially appendages. The pharmacological treatment of arrhythmia generally is focused on ventricular rate control. ...
Satoh Shinji S Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan, - - 2014
Atherosclerosis is a dise ase characterized by inflammation in the arterial wall. Atherogenesis is dependent on the innate immune response involving activation of Toll-like receptors (TLRs) and the expression of inflammatory proteins, those may lead to acute coronary syndrome (ACS). We investigated the expression level of TLR-4 in ACS, as ...
Sankaranarayanan R - - 2014
Atrial fibrillation (AF) continues to impose a significant burden upon healthcare resources. A sustained increase in the ageing population and better survival from conditions such as ischaemic heart disease have ensured that both the incidence and prevalence of AF continue to increase significantly. AF can lead to complications such as ...
Dumotier Berengere M - - 2014
The underlying mechanisms behind cardiac arrhythmias are described in this manuscript. In clinical practice, significant arrhythmias are unpredictable, and under some conditions, potentially life-threatening. How can basic science help improve our understanding of molecular entities and factors behind the arrhythmia to advance, develop, adapt or deliver available medications? Structural heart ...
Mc Ardle Brian A BA Department of Medicine (Division of Cardiology), University of Ottawa Heart Institute, Ottawa, Canada; National Cardiac PET Center, University of Ottawa Heart Institute, Ottawa, - - 2014
-Cardiac Allograft Vasculopathy (CAV) is a key prognostic determinant following heart transplant (HT). Detection and risk stratification of patients with CAV is problematic. Positron emission tomography (PET) using Rubidium-82 (Rb-82) allows quantification of absolute myocardial blood flow and may have utility for risk stratification in this population. -Patients with a ...
Bajaj Sharad S Departments of 1Cardiovascular Diseases and 2Electrophysiology, St. Michael's Medical Center, Newark, - - 2014
Brugada syndrome predisposes individuals to ventricular arrhythmias and sudden cardiac death, in the absence of structural heart disease. The typical Brugada electrocardiogram (ECG) phenotype is often concealed in affected population, and the existing genetic testing is capable of detecting just about 20% of cases. Therefore, the diagnosis largely requires various ...
Kotecha Dipak D University of Birmingham Centre for Cardiovascular Sciences, Birmingham, UK; Clinical Trials and Evaluation Unit, Royal Brompton and Harefield NHS Trust, London, UK; Centre of Cardiovascular Research and Education in Therapeutics, Monash University, Melbourne, VIC, Australia. Electronic address: - - 2014
Atrial fibrillation and heart failure often coexist, causing substantial cardiovascular morbidity and mortality. β blockers are indicated in patients with symptomatic heart failure with reduced ejection fraction; however, the efficacy of these drugs in patients with concomitant atrial fibrillation is uncertain. We therefore meta-analysed individual-patient data to assess the efficacy ...
Mart Christopher Robin CR Division of Pediatric Cardiology, Department of Pediatrics, Primary Children's Hospital, University of Utah, 100 North Mario Capecchi Drive, Salt Lake, UT, 84113, USA, - - 2014
Neonates born with borderline left heart hypoplasia, or hypoplastic left heart complex, can undergo biventricular repair while those with severe left heart hypoplasia require single ventricle palliation. Deciding which patients are candidates for biventricular repair may be very difficult since there are no scoring systems to predict biventricular repair in ...
Elgendy Islam Y IY 1600 SW Archer Road, PO Box 100277 Gainesville, FL. 32610. - - 2014
Beta-adrenergic blockers remain one of the cornerstones in the management of coronary artery disease, both in chronic stable angina and myocardial infarction. These recommendations were based on studies conducted in the era prior to the establishment of the modern therapy for ischemic heart disease and myocardial infarction i.e. anti-platelet therapy, ...
Sanborn Timothy A TA NorthShore University HealthSystem, Evanston, IL, - - 2014
Objective: To assess the relationship of femoral vascular closure device (VCD) use to bleeding and ischemic events in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) via different anticoagulation strategies. Background: It is unknown whether femoral VCD reduce major bleeding after primary PCI for STEMI ...
Tchantchaleishvili Vakhtang V Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, USA - - 2014
Transcatheter device closure of atrial septal defects (ASDs) is a minimally invasive technique that offers an alternative to conventional surgical repair. There are risks imposed by this technique; however, they compare favourably with risks of surgical closure. Here, we present a case of a 59-year old male with late erosion ...
Hayward Robert M RM Division of Cardiology, Department of Medicine, University of California, San - - 2014
Late after surgical repair of complex congenital heart disease, atrial arrhythmias are a major cause of morbidity, and ventricular arrhythmias and sudden cardiac death are a major cause of mortality. The six cases in this article highlight common challenges in the management of arrhythmias in the adult congenital heart disease ...
Berti Sergio S Adult Cardiology Department, Ospedale del Cuore G. Pasquinucci, Fondazione Toscana G. Monasterio, Massa, Italy. Electronic address: - - 2014
This dual-center study sought to demonstrate the utility and safety of intracardiac echocardiography (ICE) in providing adequate imaging guidance as an alternative to transesophageal echocardiography (TEE) during Amplatzer Cardiac Plug device implantation. Over 90% of intracardiac thrombi in atrial fibrillation originate from the left atrial appendage (LAA). Patients with contraindications ...
Lim Siok P SP Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, Ottawa, Ontario, - - 2014
Heart failure presents a significant problem in industrialized countries, with a high prevalence, morbidity, and mortality, where it is most frequently caused by coronary artery disease. Revascularization in patients with symptomatic heart failure has been associated with improved cardiovascular outcomes. Predictors of outcome benefit from revascularization include the presence and ...
de Luna Antonio Bayés AB Santa Creu i Sant Pau Hospital, Cardiovascular Research Center, CSIC-ICCC, Barcelona, - - 2014
For many years was considered that negative T wave in ischemic heart disease represents ischemia and for many authors located in subepicardial area. We performed a review based in the literature and in the experience of the authors commenting the real significance of the presence of negative T wave in ...
Páll Alida A University of Debrecen Clinical Center, Institute of Medicine, Department of Gastroenterology, Debrecen, - - 2014
Hyperdynamic circulation, systolic and diastolic left ventricular dysfunction and certain electrophysiological abnormalities have been associated with cirrhosis and known for a long time. These clinical features have been introduced as cirrhotic cardiomyopathy (CCM), which is characterized by blunted myocardial contractile responsiveness to physical, physiological and pharmacological stress. Importantly, cardiac dysfunction ...
Diao Li-Wei LW Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, - - 2014
A large number of wearable and implantable electronic medical devices are widely used in clinic and playing an increasingly important role in diagnosis and treatment, but the limited battery capacity restricts their service life and function expansion. Piezoelectric nanogenerators can convert mechanical energy into electrical energy. Our experiment tries to ...
Wan Chun-Xiao CX Rehabilitation Medicine Center, Chinese PLA General Hospital, Beijing 100853, China ; Rehabilitation Medicine Department, Wuxi No.2 Hospital Affiliated with Nanjing Medical University, Nanjing 214002, Jiangsu Province, - - 2014
Previous studies showed that hypoxia preconditioning could protect cardiac function against subsequent myocardial infarction injury. However, the effect of hypoxia on left ventricular after myocardial infarction is still unclear. This study therefore aims to investigate the effects of hypoxia training on left ventricular remodeling in rabbits post myocardial infarction. ADULT ...
Chen Ying Y Emergency Department, First Hospital of Hebei Medical University, Hebei Medical University, No. 89 Donggang Road, Shijiazhuang 050032, Hebei Province, - - 2014
The relationship between lipids and coronary artery disease has been well established. However, this is not the case between lipids and heart failure. Ironically, high lipid levels are associated with better outcomes in heart failure, but the mechanisms underlying the phenomenon are not fully understood. This study was performed to ...
Lee Joowon J Department of Pediatrics, Seoul National University Children's Hospital, Seoul, - - 2014
Milrinone is often used in children to treat acute heart failure and prevent low cardiac output syndrome after cardiac surgery. Due to the lack of studies on the long-term milrinone use in children, the objective of this study was to assess the safety and efficacy of the current patterns of ...
Kharwar Rajiv Bharat RB Department of Cardiology, King Georges' Medical University, Lucknow, - - 2014
Peripartum cardiomyopathy is a cardiac condition characterized by development of heart failure during the last month of pregnancy or during the first five months of post partum period without any other identifiable cause of heart failure. The hypercoagulable state in the pregnancy along with left ventricular (LV) systolic dysfunction predisposes ...
Ganjehei Leila L Department of Cardiology, University of Cincinnati, Cincinnati, OH, - - 2014
ABSTRACT  ST elevation myocardial infarction (STEMI) remains a leading cause of morbidity, mortality and disability worldwide. Statistically, a trend towards improvements in morbidity and mortality has been consistent over the years, which is attributed primarily to the modification of risk factors, healthier lifestyles, treatment advances and better management of door-to-balloon ...
Arabia Francisco A FA Mechanical Circulatory Support Program, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Boulevard, Suite A3600, Los Angeles, CA 90048, - - 2014
ABSTRACT  The medical/surgical management of advanced heart failure has evolved rapidly over the last few decades. With better understanding of heart failure pathophysiology, new pharmacological agents have been introduced that have resulted in improvements in survival. For those patients that fail to improve, mechanical circulatory support with left ventricular assist ...
Yuan Shi-Min SM Teaching Hospital, Fujian Medical University, Putian, - - 2014
This article aims to present updated therapeutic options for fetal congenital heart diseases. Data source for the present study was based on comprehensive literature retrieval on fetal cardiac interventions in terms of indications, technical approaches and clinical outcomes. About 5% of fetal congenital heart diseases are critical and timely intrauterine ...
Juliani Paulo Sérgio PS Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, - - 2014
A feature of dilated cardiomyopathy is the deformation of ventricular cavity, which contributes to systolic dysfunction. Few studies have evaluated this deformation bearing in mind ventricular regions and segments of the ventricle, which could reveal important details of the remodeling process, supporting a better understanding of its role in functional ...
Gandolfo Fabrizio F Freeman Hospital, Newcastle Upon Tyne, NE7 7DN, - - 2014
There is no reliable published data on the overall prevalence or incidence of heart failure (HF) in children. However, the success of mechanical circulatory support (MCS) in management of HF has raised the prospect of a previously unavailable treatment modality. Orthotopic heart transplant (OHTx) remains the gold standard treatment, but ...
Tchantchaleishvili Vakhtang V 1 Division of Cardiothoracic Surgery, 2 Department of Cardiology, University of Rochester Medical Center, Rochester, NY 14642, - - 2014
Ventricular assist devices (VADs) are not fully biocompatible, and are therefore predisposed to device thrombosis and subsequent pump dysfunction. Clinically significant hemolysis in VADs most often occurs as a result of device thrombosis, but can also be caused by other factors. Herein we describe the evaluation and management of VAD ...
Zannad Faiez F Inserm, CIC 1433, Centre Hospitalier Universitaire, Department of Cardiology, Nancy University, Université de Lorraine, Nancy, France - - 2014
The neural cardiac therapy for heart failure (NECTAR-HF) was a randomized sham-controlled trial designed to evaluate whether a single dose of vagal nerve stimulation (VNS) would attenuate cardiac remodelling, improve cardiac function and increase exercise capacity in symptomatic heart failure patients with severe left ventricular (LV) systolic dysfunction despite guideline ...
Fox Kim K From the National Heart and Lung Institute, Imperial College, Institute of Cardiovascular Medicine and Science, Royal Brompton Hospital, London (K.F., P.G.S.), and the Robertson Centre for Biostatistics, University of Glasgow, Glasgow (I.F.) - both in the United Kingdom; Département Hospitalo-Universitaire Fibrosis Inflammation Remodeling, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, INSERM Unité 1148, and Université Paris-Diderot, Sorbonne Paris Cité - all in Paris (P.G.S.); the Montreal Heart Institute Coordinating Centre, Université de Montréal, Montreal (J.-C.T.); the Third Division of Cardiology, Medical University of Silesia, Katowice, Poland (M.T.); and the Department of Cardiology and Laboratory for Technologies of Advanced Therapies Center, University Hospital of Ferrara and Maria Cecilia Hospital, GVM Care and Research, Ettore Sansavini Health Science Foundation, Cotignola, Italy - - 2014
Background An elevated heart rate is an established marker of cardiovascular risk. Previous analyses have suggested that ivabradine, a heart-rate-reducing agent, may improve outcomes in patients with stable coronary artery disease, left ventricular dysfunction, and a heart rate of 70 beats per minute or more. Methods We conducted a randomized, ...
Imbrogno S S Dept. of Biology, Ecology and Earth Sciences (B.E.ST), University of Calabria, Arcavacata di Rende (CS), Italy. Electronic address: - - 2014
Goldfish tolerate prolonged and severe hypoxia, thus representing a well-suited model to study the maintenance of cardiac function when O2 availability represents a limiting factor. Using a working heart preparation, we explored the role of the intracardiac nitric oxide synthase (NOS)-derived Nitric Oxide (NO) under normoxic and hypoxic conditions. Cardiac ...
Abe Hajime H Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan; Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahicho, Fuchu-shi, Tokyo 183-0003, Japan. Electronic address: - - 2014
Detecting the presence of coronary artery disease (CAD) is critically important in managing patients with heart failure of uncertain cause. The recently introduced (123)I-BMIPP/(201)TlCl dual myocardial single-photon emission computed tomography (dual SPECT) is potentially a non-invasive diagnostic tool in detecting ischemic heart disease. The aim of our study is to ...
Chudzik Michal M Department of Electrocardiology, Medical University of Lodz, - - 2014
There is no consensus on the length of ECG tracing that should be recorded to represent adequate rate control in patients with atrial fibrillation (AFib). The purpose of the study was to examine whether heart rate measurements based on short-term ECGs recorded at different periods of the day may correspond ...
Li Mengmeng M State Key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, 210029, - - 2014
Polychlorinated biphenyls (PCBs) are ubiquitous environmental pollutants that may pose significant health-risks to various organisms including humans. Although the mixed PCB Aroclor 1254 is widespread in the environment, its potential toxic effect on heart development and the mechanism underlying its developmental toxicity have not been previously studied. Here, we used ...
Huang Bing B Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, P.R. - - 2014
Recently, a beneficial effect of renal sympathetic denervation (RSD) has been seen in patients with ventricular electrical storm. However, the effect of RSD on ventricular electrophysiology remains unclear. Thirty-three mongrel dogs were included in the present study. RSD was performed by radiofrequency ablation of the adventitial surface of the renal ...
Allen Scott F SF Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA. Electronic address: - - 2014
A previously healthy 48-year-old woman was evaluated for lightheadedness and chest heaviness 2 weeks after starting the herbal supplement Garcinia cambogia. She was found to be hypotensive and had an elevated serum troponin level. The patient had a progressive clinical decline, ultimately experiencing fulminant heart failure and sustained ventricular arrhythmias, ...
Fang Jie J Department of Orthodontics, West China Hospital of Stomatology, State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, - - 2014
Molecular switches of myosin isoforms are known to occur in various conditions. Here, we demonstrated the result from fetal heart failure and its potential mechanisms. Fetal and adult heart failure rat models were induced by injections of isoproterenol as previously described, and Go6976 was given to heart failing fetuses. Real-time ...
Malakan Rad Elaheh E Section of Pediatric Cardiology, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, Tehran, - - 2014
Congenital left ventricular outpouchings (LVOs) are reported under five overlapping and poorly defined terms including left ventricular accessory chamber, left ventricular aneurysm (LVA), left ventricular diverticulum (LVD), double-chambered LV, and accessory left ventricle. Diagnostic criteria are frequently mixed and not mutually exclusive. They convey no information regarding treatment strategy and ...
Nagao Michinobu M Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
Right ventricular (RV) failure and ventricular dyssynchrony are strong determinants of prognosis in patients with adult congenital heart disease (ACHD). The aim of this study was to investigate the relationship between interventricular dyssynchrony (IVD) using cine-tagged magnetic resonance imaging (MRI) and RV dysfunction in ACHD patients. Sixty-seven patients with ACHD ...
Korkmaz K K Department of Cardiovascular Surgery, Ankara Numune sResearch and Training Hospital, Ankara, Turkey. - - 2014
Left ventricular pseudo-aneurysms develop when cardiac rupture is contained by pericardial adhesions or scar tissue due to myocardial infarction, surgery, trauma or infection. Left ventricular pseudo-aneurysms are uncommon, difficult to diagnose and prone to cardiac rupture. Urgent surgical repair is recommended. Here we report on a case of a large ...
Haworth Thomas Eliot TE University of - - 2014
To extend our knowledge of fish cardiac excitability to a Chondrostei fish, we examined electrophysiological phenotype of the Siberian sturgeon (Acipenser baerii) heart. Epicardial ECG of A.baerii had typical waveform of vertebrate ECG with Q-T interval of 650 ± 30 ms and an intrinsic heart rate of 45.5 ± 5 ...
Gandhi Parul U PU Division of Cardiology, Massachusetts General Hospital, Boston, - - 2014
Insulin-like growth factor-binding protein 7 (IGFBP7) is a biomarker that has recently been associated with heart failure and cardiac hypertrophy. The aim of this study was to examine IGFBP7 relative to echocardiographic abnormalities reflecting diastolic dysfunction. One hundred twenty-four patients with ambulatory heart failure with reduced ejection fraction and baseline ...
Winchester David E DE Division of Cardiovascular Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, - - 2014
Considerable progress has been made over the last few decades in the management of clinically stable coronary heart disease (SCHD), including improvements in interventions (e.g., percutaneous revascularization), pharmacological management, and risk factor control (e.g., smoking, diet, activity level, hypercholesterolemia, hypertension). Although β blockers have long been used for the treatment of ...
Tomson Todd T TT Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, 676 North St. Claire, Suite 600, Chicago, IL 60611, - - 2014
Insertable cardiac monitors (ICMs) are leadless subcutaneous devices that continuously monitor the heart rhythm and record events over a timeframe measured in years, allowing for the diagnosis of infrequent rhythm abnormalities that can be the cause of palpitations, syncope and stroke. To date, ICMs have primarily been used in the ...
Chan Ngai-Yin NY Consultant, Princess Margaret Hospital, Hong - - 2014
A 64-year-old woman underwent left atrial appendage occlusion with an Amplatzer Cardiac Plug device. Displacement of the device was detected on day 1 with transeosophageal echocardiographic checking. The device became dislodged and flitted in the left atrium after unsuccessful retrieval with a snare and 12F steerable transseptal sheath. A double ...
Maroszyńska Iwona I 1Department of Intensive Care and Congenital Malformations of the Neonates and - - 2014
Congenital diaphragmatic hernia (CDH) is a malformation with a diverse clinical picture. Its severity can be assessed prenatally using the lung area to head circumference ratio (LHR). LHR lower than 1 as associated with high mortality is an indication for prenatal treatment involving occlusion of fetal trachea. Before such treatment ...
Lowalekar S K SK Cardiothoracic Surgery Division, Departments of Surgery, Harvard Medical School, Boston, MA; Brigham and Women's Hospital, Boston, MA; VA Boston Healthcare System, Boston, - - 2014
Organ preservation at 4°C results in temporally irreversible injury to cellular structure and function. This study was designed to evaluate the possibility of storing hearts at ambient temperatures in novel organ preservation solution Somah to prevent damage and preserve optimum function by maintaining cellular energy over the temperature range of ...
Haeusler Karl Georg KG - - 2014
"Lone" atrial fibrillation (AF) is generally used to refer to patients with AF in the absence of structural heart disease. When the decision for oral anticoagulation is discussed, "lone" AF refers to patients who do not have established stroke risk factors. Imaging is often used to rule out structural heart ...
< 2 3 4 5 6 7 8 9 10 11 12 >