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Tanaka Komei K Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, - - 2014
-Despite the increasing prevalence of heart failure (HF) with preserved ejection fraction (HFpEF) in humans, there remains no therapeutic options for HFpEF. Adiponectin (APN), an adipocyte-derived cytokine exerts cardioprotective actions and its deficiency is implicated in the development of hypertension and HF with reduced ejection fraction. Similarly APN deficiency in ...
Wasmer Kristina K Division of Clinical and Experimental Electrophysiology, Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Germany, - - 2014
Atrial fibrillation (AF) is associated with increased risk for stroke, heart failure and mortality. The causality between worse prognosis and AF is not clear at this time and AF may just be expression of underlying heart disease that by itself is associated with increased morbidity and mortality. AF is characterized ...
Unai Shinya S Shinya Unai, Hitoshi Hirose, John WC Entwistle III, Louis E Samuels, Division of Cardiothoracic Surgery, Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, United - - 2014
A 50-year-old male who underwent a HeartMate II left ventricular assist device placement for ischemic cardiomyopathy presented with discolored urine and hemolysis 3 mo after the operation. His hemolysis was thought to be due to thrombosis within the pump. Imaging studies were not able to visualize a left ventricular thrombus. ...
Dariolli Rafael R Heart Institute (InCor), University of São Paulo Medical School, São Paulo, - - 2014
The objectives of this study were to develop a robust, homogeneous, viable and inexpensive model of closed-artery catheter-based model of myocardial infarction (MI) in pigs without major cardiac dysfunction. Suitable animal models that mimic human cardiovascular conditions are of paramount importance to understand the effects of novel therapeutic strategies to ...
Min Jooncheol J Department of Thoracic and Cardiovascular Surgery, SMG-SNU Boramae Medical - - 2014
Recurrent ventricular arrhythmia can be fatal and cause serious complications, particularly when it is caused immediately after an operation. Incorrect placement of a Swan-Ganz catheter can trigger life-threatening ventricular arrhythmia, but even intensive care specialists tend to miss this fact. Here, we report a case of recurrent ventricular arrhythmia causing ...
Dai Zixuan Z Cardiovascular Research Institute of Wuhan University, Renmin Hospital of Wuhan University, Wuhan City, - - 2014
Aims: This study sought to assess whether renal sympathetic denervation (RSD) could suppress ventricular substrate remodelling and attenuate heart failure (HF) progression. Methods and results: Nineteen dogs were randomised into three groups - seven sham-operated controls, six with right ventricular pacing to induce HF, and six with RSD followed eight ...
Rajappan Kim K Cardiac Department, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Headley Way, Headington, Oxford, OX3 9DU, - - 2014
Catheter ablation of atrial fibrillation (AF) is performed increasingly worldwide and with the development of new technologies the procedures have become safer and more effective after a single attempt, particularly with paroxysmal AF. However, success rates for persistent AF ablation remain far lower than paroxysmal AF and there is large ...
Sepehripour Amir H - - 2014
Off-pump coronary artery bypass surgery (OPCAB) has been hypothesised to be beneficial in the high-risk patient population undergoing re-operative coronary artery bypass graft surgery (CABG). In addition, this technique has been demonstrated to provide subtle benefits in end-organ function including heart, lungs and kidney. The aims of this study were ...
Donaldson Erin E EE Department of Family Medicine, Methodist Charlton Medical Center, Dallas, - - 2014
We describe a 47-year-old man who underwent heart transplantation (HT) for severe right-sided heart failure and periodic episodes of ventricular tachycardia (VT) 43 years after operative repair of tetralogy of Fallot (T of F). The right-ventricular outflow tract, the site where a patch had been placed 4 decades earlier, was aneurysmal. Such ...
Mocanu Valentin V Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, - - 2014
Complete revascularization (CR) has been suggested to provide benefits to both early and long-term outcomes, but the magnitude of the benefit and frequency of incomplete revascularization (IR) after coronary artery bypass graft operations is rarely explored and is the subject of the present study. All patients who underwent isolated bypass ...
Patel Hiren H Division of Internal Medicine Residency Program, University of Illinois, Chicago, - - 2014
With conflicting evidence regarding the usefulness of intraaortic balloon pump (IABP), reports of IABP use in the United States have been inconsistent. Our objective was to examine trends in IABP usage in percutaneous coronary intervention (PCI) in the United States and to evaluate the association of IABP use with mortality. ...
Khera Sahil S New York Medical College, Valhalla, - - 2014
The influence of admission source (nursing home [NH] versus community-dwelling) on treatment strategies and outcomes among elderly patients with ST-elevation myocardial infarction (STEMI) has not been investigated. Nationwide Inpatient Sample databases from 2003 to 2010 were used to identify 270,117 community-dwelling and 4082 NH patients 75 years of age or ...
Pahlm Ulrika U Department of Clinical Physiology and Nuclear Medicine, Lund University and Skåne University Hospital, Lund, - - 2014
In a patient with chest pain and suspected acute coronary syndrome, the electrocardiogram (ECG) is the only readily available diagnostic tool. It is important to maximize its usefulness to detect acute myocardial ischemia that may evolve to myocardial infarction unless the patient is treated expediently with reperfusion therapy. Since diagnostic ...
Baharvahdat Humain H Department of Neurosurgical, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, - - 2014
Intravenous recombinant tissue plasminogen activator (rt-PA) is an approved treatment for acute ischemic stroke within 4.5 h of symptoms onset. Decompressive craniectomy (DC) has been shown as an effective therapeutic modality in malignant middle cerebral artery (MCA) infarction. As rt-PA could result in hemorrhagic complication during or after any surgery ...
Rajagopalan Navin N University of Kentucky, 900 South Limestone Street, Lexington, KY 40536 USA. - - 2014
The Impella 5.0 is a minimally invasive heart assist device that can be used to stabilize patients with cardiogenic shock. We present the case of a 49-year-old female in cardiogenic shock who required left ventricular assist device placement, but was not an optimal candidate for surgery due to severe deconditioning ...
Sciahbasi Alessandro A Interventional Cardiology, Sandro Pertini Hospital - ASL RMB, Rome. Electronic address: - - 2014
Radiation absorbed by interventional cardiologists is a frequently under-evaluated important issue. Aim is to compare radiation dose absorbed by interventional cardiologists during percutaneous coronary procedures for acute coronary syndromes comparing transradial and transfemoral access. The randomized multicentre MATRIX (Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of ...
Stein Gideon Y GY Internal Medicine "B", Beilinson Hospital, Rabin Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel-Aviv, - - 2014
Type-II MI is defined as myocardial infarction (MI) secondary to ischemia due to either increased oxygen demand or decreased supply. This categorization has been used for the last five years, yet, little is known about patient characteristics and clinical outcomes. In the current work we assessed the epidemiology, causes, management ...
Wu Nan N Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, People's Republic of - - 2014
The aim of this study was to determine the effect of picroside II on myocardial ischemia reperfusion injury in rats and to explore its underlying mechanism. Isolated rat hearts underwent 30 minutes of global ischemia followed by 120 minutes of reperfusion. Different doses of picroside II (1 μM, 10 μM, ...
Cohen Arazi Hernán H Consejo de emergencias cardiovasculares Dr. Rafael Bullrich, Sociedad Argentina de Cardiología. E-mail: - - 2014
Investigators have raised doubts as to the safety of the Swan Ganz catheter (SGC). In order to define the point of view of cardiologists in our country, the Argentine Society of Cardiology's Emergency Council organized a meeting to analyze their views in different settings (non-cardiac surgery, cardiac surgery, acute coronary ...
Stenberg Thor Allan TA Cardiovascular Research Group, Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Cardiothoracic and Vascular Surgery, University Hospital of North Norway, Tromsø, - - 2014
The mechanisms contributing to multiorgan dysfunction during cardiogenic shock are poorly understood. Our goal was to characterize the microcirculatory and mitochondrial responses following ≥10 hours of severe left ventricular failure and cardiogenic shock. We employed a closed-chest porcine model of cardiogenic shock induced by left coronary microembolization (nā€Š=ā€Š12) and a ...
Baumann Stefan S First Department of Medicine, Faculty of Medicine Mannheim, University Medical Center Mannheim (UMM), University of Heidelberg, Mannheim, - - 2014
Takotsubo cardiomyopathy (TC) is characterized by the abrupt onset of cardiac dysfunction, with transient apical and midventricular hypo-/akinesia with a compensatory hypercontractility of the remaining segments. The clinical presentation appears to be similar to acute myocardial infarction (AMI). However, the myocardial dysfunction is reversible. We report on the case of ...
Rostagno C C Department of sperimental and clinical medicine, University of - - 2014
Postoperative atrial fibrillation after isolated coronary revascularization has been associated with increased morbidity and mortality. Aim of present investigation was to evaluate incidence of postoperative atrial fibrillation and its prognostic role in patients undergoing isolated coronary artery by-pass and disclose possible differences between off-pump and cardiopulmonary assisted revascularization. Prospective cohort ...
Kelly R P RP Department of Surgery, Dalhousie University, Halifax, - - 2014
A 58-year-old woman with vascular Ehlers-Danlos syndrome (EDS; type IV) presented to a Canadian tertiary care emergency department with a non-ST elevation myocardial infarction. The patient failed medical therapy and after careful consideration of the options, elected to undergo urgent coronary artery bypass (CABG) surgery. To the best of our ...
Tsaousi Georgia G 0000-0003-3806-837X Department of Anesthesiology and ICU, Faculty of Medicine, Aristotle University of Thessaloniki, Stilponos Kiriakidi 1, 54636 Thessaloniki, - - 2014
Aim. To comparably assess the perioperative risk factors that differentiate off-pump coronary artery bypass (OPCAB) grafting cases from those sustaining unplanned conversion to on-pump beating heart (ONCAB/BH) approach, in patients with left ventricular ejection fraction (LVEF) < 40%. Methods. Perioperative variables were retrospectively assessed in 216 patients with LVEF < ...
Jin Pei-Yin PY Department of Cardiovascular Medicine, The People's Hospital of Anyang, Anyang, Henan, China. - - 2014
Glucose-insulin-potassium (GIK) has been advocated in the setting of acute coronary syndrome (ACS) to reduce ischemia-related arrhythmias and myocardial injury. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess whether the use of GIK infusions >3 or <3 hours after the onset of symptoms reduce mortality or cardiac ...
Vijayalakshmi I B - - 2013
Amplatzer Duct Occluder II (ADO II) is especially designed for closing long ducts in infants. The experience with off-label use of the ADO II in non-ductal positions is limited. Aim: To evaluate feasibility of use of ADO II in non-ductal positions, occurrence of complete heart block (CHB), advantages and disadvantages. ...
Lazar John F - - 2013
Right ventricular (RV) failure after the insertion of a left ventricular assist device (LVAD) historically results in poor outcomes. Patients requiring temporary RV support after LVAD insertion are a heterogeneous group of patients consisting of those in cardiogenic shock after myocardial infarction, to those with chronic decompensated heart failure. For ...
Zhou Zhichao - - 2013
We previously demonstrated that uridine adenosine tetraphosphate (Up4A) exerts a potent vasodilator effect in the healthy porcine coronary vasculature. Since the coronary microvascular effects of Up4A after myocardial infarction (MI) are unknown, the present study investigated the response to Up4A in coronary microvessels from post-MI remodeled porcine myocardium, and the ...
Núñez-Gil Iván J - - 2013
To assess the relationship between functional mitral regurgitation (MR) after a non-ST segment elevation acute coronary syndrome (NSTSEACS) and long-term prognosis, ventricular remodelling and further development of atrial fibrillation (AF), since functional MR is common after myocardial infarction. Prospective cohort study conducted in a tertiary referral centre. We prospectively studied ...
Minha Sa'ar - - 2013
The Food and Drug Administration held a Circulatory System Devices Advisory Panel meeting, December 5 and 6, 2012, to review the classification or potential reclassification of the following device types: external counterpulsation, intra-aortic balloon pump (IABP), and non-roller-type cardiopulmonary bypass blood pumps. These 3 devices are preamendment (Medical Device Amendments ...
Salick Muhammad Musa MM Department of Cardiothoracic Surgery, Aga Khan University Hospital, Karachi, - - 2013
improvements in nonsurgical revascularization have left a group of higher-risk patients presenting for operation in a later stage of coronary artery disease. We undertook this study to analyze temporal changes in demographic and clinical profiles and outcomes of cardiac surgical patients. we identified and retrieved preoperative, intraoperative, and postoperative variables ...
Sasaki Shunsuke - - 2013
BACKGROUND: Acute Stanford type A aortic dissection (AAD) with coronary involvement is associated with high mortality. However, coronary involvement is not always successfully visualized by computed tomography and two-dimensional (2D) transesophageal echocardiography (TEE). The aim of this study was to test the hypothesis that three-dimensional (3D) TEE can detect coronary ...
Moak Jeffrey P - - 2013
BACKGROUND: -Supraventricular arrhythmias (junctional ectopic tachycardia (JET) and atrial tachyarrhythmias (AT)) frequently complicate recovery from open heart surgery (OHS) in children and can be difficult to manage. Medical treatment of JET can result in significant morbidity. Our goal was to develop a non-pharmacologic approach using autonomic stimulation of selective fat ...
Hoashi Takaya - - 2013
BACKGROUND: The changes of left ventricular function after undergoing a Ross-Konno operation for pediatric patients with multiple-level left ventricular outflow tract obstruction are still unclear. METHODS: From 1996 to 2006, 14 patients younger than 20 years underwent a Ross-Konno operation. The mean age at the time of the operation was ...
Belway Dean - - 2013
Left ventricular assist device technology has improved such that mechanical malfunction, particularly with newer generation continuous flow devices, is a relatively rare event. We present a case of sudden power loss in a HeartMate II caused by intermittent contact of the battery terminals after a clip was dropped with the ...
Suzuki R - - 2013
OBJECTIVES: To evaluate left ventricular geometry in dogs with various stages of myxomatous mitral valve disease. METHODS: Ninety-seven dogs with myxomatous mitral valve disease classified by the International Small Animal Cardiac Health Council system and 20 weight- and age-matched healthy dogs. Left ventricular long-axis to short-axis ratio, sphericity index in ...
Sareyyupoglu Basar - - 2013
A 73-year-old patient supported by a HeartMate II ventricular assist device (VAD) (Thoratec Corp, Pleasanton, CA) experienced erosion of the outflow graft caused by the disconnection of the bend relief. He underwent successful surgical repair.
Ulas Turgay - - 2013
Contrast induced kidney injury is an acute renal dysfunction that is secondary to the administration of radio contrast media. The purpose of this study was to evaluate the levels of urotensin-II (UT-II) and endothelin-I (ET-I) after contrast media administration in patients undergoing percutaneous coronary interventions. In this prospective cohort study, ...
Hosseini Morteza Tavakkoli - - 2013
BACKGROUND: HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry. METHODS: The left ventricular end diastolic ...
Rohn V - - 2013
The incidence of post infarction ventricular septal rupture (PIVSR) is decreasing in the last years due to aggressive treatment of myocardial infarction with early percutaneous coronary interventions. As a consequence patients with PIVSR are referred to surgery more often with significant heart failure. The aim of this retrospective study was ...
Kurabayashi Manabu - - 2013
Calcium antagonists, nicorandil and long-acting nitrates are highly effective for preventing coronary spasm. The withdrawal of coronary vasodilators, especially calcium antagonists, is risky in cases of vasospastic angina. We herein present a case of cardiopulmonary arrest that occurred due to coronary spasm triggered by the discontinuation of coronary vasodilators during ...
Li Yongjun - - 2013
Loss of cardiomyocytes after myocardial infarction (MI) causes heart failure. In this study, we investigate whether the in situ cardiomyocytes can re-enter the cell cycle and to what extent cell division of cardiomyocytes occurs after acute MI (AMI) in rats. Sprague Dawley (SD) rats were used in this study; the ...
Pang Philip Yk - - 2013
To review the experience of surgical repair of post-infarction ventricular septal rupture (VSR) and analyze the associated outcomes and prognostic factors. Following approval from the Singhealth Centralised Institutional Review Board (reference: 2011/881/C), a retrospective review was performed on 38 consecutive patients who had undergone surgical repair of post-infarction VSR between ...
Barold S Serge - - 2012
Type I second-degree atrioventricular (AV) block describes visible, differing, and generally decremental AV conduction. The literature contains numerous differing definitions of second-degree AV block, especially Mobitz type II second-degree AV block. The widespread use of numerous disparate definitions of type II block appears primarily responsible for many of the diagnostic ...
Yang Wei - - 2012
To observe the expression of angiotensin converting enzyme (ACE), angiotensin II (Ang II), cardiac troponin (cTn I), creatine kinase isozymes (CK-MB) and muscle red protein(Myo) after cardiopulmonary bypass (CPB), and to investigate the association of polymorphisms in angiotensin converting enzyme genes and myocardial injury. Sixty-three patients suffered from rheumatic mitral ...
Mittal S R - - 2012
There is only scanty data on tissue Doppler imaging (TDI) of 'normal' adults. Twenty eight asymptomatic adults (20-45 yrs) without cardiovascular risk factors, clinic BP < or = 120/80mmHg and normal echocardiographic examination were evaluated by tissue Doppler imaging to find normal reference values in this population. There was significant ...
Moss Joshua D JD Department of Medicine, Section of Cardiology, University of Chicago, Chicago, Illinois 60614, USA. - - 2012
BACKGround : Left lateral accessory pathway (AP) location along the mitral annulus (MA) can influence ablation strategy, including choice of a transseptal or retrograde aortic approach and the use of deflectable sheaths and/or bidirectional catheters. We aimed to develop electrocardiographic (ECG) criteria to accurately localize a left lateral AP, hypothesizing ...
Devendran Vimalarani - - 2012
Ventricular septal defect (VSD) is a common congenital heart defect in children. Perimembranous VSD (Pm VSD), a defect involving the membranous septum and the adjacent portion of the muscular septum, accounts for about 70 % of cases. Transcatheter closure of Pm VSDs using the Amplatzer Pm VSD device, although successful in ...
Yu Chung-Hoon - - 2012
Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a ...
Tweet Marysia S - - 2012
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is an acute coronary event of uncertain etiology. Clinical features and prognosis remain insufficiently characterized. METHODS AND RESULTS: A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Incidence, clinical characteristics, treatment modalities, in-hospital outcomes and long-term risk of SCAD recurrence or ...
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